David A. Baker, Ph.D. - Publications

Affiliations: 
Marquette University Marquette University, Milwaukee, WI, United States 

237 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Vranjkovic O, Van Newenhizen E, Nordness ME, Blacktop JM, Urbanik LA, Mathy JC, McReynolds JR, Miller AM, Doncheck EM, Kloehn TM, Stinnett GS, Gerndt CH, Ketchesin KD, Baker DA, Seasholtz AF, et al. Enhanced CRFR1-dependent regulation of a ventral tegmental area to prelimbic cortex projection establishes susceptibility to stress-induced cocaine seeking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30355627 DOI: 10.1523/Jneurosci.2080-18.2018  0.454
2017 McReynolds JR, Doncheck EM, Li Y, Vranjkovic O, Graf EN, Ogasawara D, Cravatt BF, Baker DA, Liu QS, Hillard CJ, Mantsch JR. Stress Promotes Drug Seeking Through Glucocorticoid-Dependent Endocannabinoid Mobilization in the Prelimbic Cortex. Biological Psychiatry. PMID 29100630 DOI: 10.1016/J.Biopsych.2017.09.024  0.336
2017 Wheeler DS, Ebben AL, Kurtoglu B, Lovell ME, Bohn AT, Jasek IA, Baker DA, Mantsch JR, Gasser PJ, Wheeler RA. Corticosterone regulates both naturally occurring and cocaine-induced dopamine signaling by selectively decreasing dopamine uptake. The European Journal of Neuroscience. PMID 28965353 DOI: 10.1111/Ejn.13730  0.411
2016 McReynolds JR, Taylor A, Vranjkovic O, Ambrosius T, Derricks O, Nino B, Kurtoglu B, Wheeler RA, Baker DA, Gasser PJ, Mantsch JR. Corticosterone Potentiation of Cocaine-Induced Reinstatement of Conditioned Place Preference in Mice is Mediated by Blockade of the Organic Cation Transporter 3. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27604564 DOI: 10.1038/Npp.2016.187  0.449
2016 Hsia Y, Bale JB, Gonen S, Shi D, Sheffler W, Fong KK, Nattermann U, Xu C, Huang PS, Ravichandran R, Yi S, Davis TN, Gonen T, King NP, Baker D. Design of a hyperstable 60-subunit protein icosahedron. Nature. PMID 27309817 DOI: 10.1038/Nature18010  0.307
2016 Ovchinnikov S, Park H, Kim DE, Liu Y, Yu-Ruei Wang R, Baker D. Structure Prediction using sparse simulated NOE restraints with Rosetta in CASP11. Proteins. PMID 26857542 DOI: 10.1002/Prot.25006  0.301
2016 Kong L, Albano R, Madayag A, Raddatz N, Mantsch JR, Choi S, Lobner D, Baker DA. Pituitary Adenylate Cyclase-Activating Polypeptide Orchestrates Neuronal Regulation of the Astrocytic Glutamate Releasing Mechanism System xc. Journal of Neurochemistry. PMID 26851652 DOI: 10.1111/Jnc.13566  0.747
2016 Taylor ND, Garruss AS, Moretti R, Chan S, Arbing MA, Cascio D, Rogers JK, Isaacs FJ, Kosuri S, Baker D, Fields S, Church GM, Raman S. Engineering an allosteric transcription factor to respond to new ligands. Nature Methods. 13: 177-83. PMID 26689263 DOI: 10.1038/Nmeth.3696  0.304
2015 Ovchinnikov S, Kim DE, Wang RY, Liu Y, DiMaio F, Baker D. Improved de novo structure prediction in CASP11 by incorporating Co-evolution information into rosetta. Proteins. PMID 26677056 DOI: 10.1002/Prot.24974  0.306
2015 Brunette TJ, Parmeggiani F, Huang PS, Bhabha G, Ekiert DC, Tsutakawa SE, Hura GL, Tainer JA, Baker D. Exploring the repeat protein universe through computational protein design. Nature. PMID 26675729 DOI: 10.1038/Nature16162  0.341
2015 Blacktop JM, Vranjkovic O, Mayer M, Van Hoof M, Baker DA, Mantsch JR. Antagonism of GABA-B but not GABA-A receptors in the VTA prevents stress- and intra-VTA CRF-induced reinstatement of extinguished cocaine seeking in rats. Neuropharmacology. PMID 26596556 DOI: 10.1016/J.Neuropharm.2015.11.013  0.405
2015 Huang PS, Feldmeier K, Parmeggiani F, Fernandez Velasco DA, Höcker B, Baker D. De novo design of a four-fold symmetric TIM-barrel protein with atomic-level accuracy. Nature Chemical Biology. PMID 26595462 DOI: 10.1038/Nchembio.1966  0.308
2015 Bednar D, Beerens K, Sebestova E, Bendl J, Khare S, Chaloupkova R, Prokop Z, Brezovsky J, Baker D, Damborsky J. FireProt: Energy- and Evolution-Based Computational Design of Thermostable Multiple-Point Mutants. Plos Computational Biology. 11: e1004556. PMID 26529612 DOI: 10.1371/Journal.Pcbi.1004556  0.301
2015 McReynolds JR, Doncheck EM, Vranjkovic O, Ganzman GS, Baker DA, Hillard CJ, Mantsch JR. CB1 receptor antagonism blocks stress-potentiated reinstatement of cocaine seeking in rats. Psychopharmacology. PMID 26455361 DOI: 10.1007/S00213-015-4092-X  0.412
2015 Holstein CA, Chevalier A, Bennett S, Anderson CE, Keniston K, Olsen C, Li B, Bales B, Moore DR, Fu E, Baker D, Yager P. Immobilizing affinity proteins to nitrocellulose: a toolbox for paper-based assay developers. Analytical and Bioanalytical Chemistry. PMID 26427504 DOI: 10.1007/S00216-015-9052-0  0.301
2015 Lin YR, Koga N, Tatsumi-Koga R, Liu G, Clouser AF, Montelione GT, Baker D. Control over overall shape and size in de novo designed proteins. Proceedings of the National Academy of Sciences of the United States of America. PMID 26396255 DOI: 10.1073/Pnas.1509508112  0.317
2015 Ovchinnikov S, Kinch L, Park H, Liao Y, Pei J, Kim DE, Kamisetty H, Grishin NV, Baker D. Large scale determination of previously unsolved protein structures using evolutionary information. Elife. 4. PMID 26335199 DOI: 10.7554/Elife.09248  0.325
2015 Park H, DiMaio F, Baker D. CASP11 refinement experiments with ROSETTA. Proteins. PMID 26205421 DOI: 10.1002/Prot.24862  0.311
2015 Bale JB, Park RU, Liu Y, Gonen S, Gonen T, Cascio D, King NP, Yeates TO, Baker D. Structure of a designed tetrahedral protein assembly variant engineered to have improved soluble expression. Protein Science : a Publication of the Protein Society. PMID 26174163 DOI: 10.1002/Pro.2748  0.309
2015 Gonen S, DiMaio F, Gonen T, Baker D. PROTEIN DESIGN. Design of ordered two-dimensional arrays mediated by noncovalent protein-protein interfaces. Science (New York, N.Y.). 348: 1365-8. PMID 26089516 DOI: 10.1126/Science.Aaa9897  0.302
2015 Mantsch JR, Baker DA, Funk D, Lê AD, Shaham Y. Stress-Induced Reinstatement of Drug Seeking: 20 Years of Progress. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 25976297 DOI: 10.1038/Npp.2015.142  0.348
2015 Antala S, Ovchinnikov S, Kamisetty H, Baker D, Dempski RE. Computational modeling and functional studies provide a structural scaffold for the zinc transporter hZIP4. The Journal of Biological Chemistry. PMID 25971965 DOI: 10.1074/Jbc.M114.617613  0.317
2015 Park H, DiMaio F, Baker D. The origin of consistent protein structure refinement from structural averaging. Structure (London, England : 1993). 23: 1123-8. PMID 25960407 DOI: 10.1016/J.Str.2015.03.022  0.302
2015 Pearson AD, Mills JH, Song Y, Nasertorabi F, Han GW, Baker D, Stevens RC, Schultz PG. Transition states. Trapping a transition state in a computationally designed protein bottle. Science (New York, N.Y.). 347: 863-7. PMID 25700516 DOI: 10.1126/Science.Aaa2424  0.303
2015 Park K, Shen BW, Parmeggiani F, Huang PS, Stoddard BL, Baker D. Control of repeat-protein curvature by computational protein design. Nature Structural & Molecular Biology. 22: 167-74. PMID 25580576 DOI: 10.1038/Nsmb.2938  0.308
2015 Parmeggiani F, Huang PS, Vorobiev S, Xiao R, Park K, Caprari S, Su M, Seetharaman J, Mao L, Janjua H, Montelione GT, Hunt J, Baker D. A general computational approach for repeat protein design. Journal of Molecular Biology. 427: 563-75. PMID 25451037 DOI: 10.1016/J.Jmb.2014.11.005  0.317
2015 Rossi P, Shi L, Liu G, Barbieri CM, Lee HW, Grant TD, Luft JR, Xiao R, Acton TB, Snell EH, Montelione GT, Baker D, Lange OF, Sgourakis NG. A hybrid NMR/SAXS-based approach for discriminating oligomeric protein interfaces using Rosetta. Proteins. 83: 309-17. PMID 25388768 DOI: 10.1002/Prot.24719  0.325
2014 Liu DS, Nivón LG, Richter F, Goldman PJ, Deerinck TJ, Yao JZ, Richardson D, Phipps WS, Ye AZ, Ellisman MH, Drennan CL, Baker D, Ting AY. Computational design of a red fluorophore ligase for site-specific protein labeling in living cells. Proceedings of the National Academy of Sciences of the United States of America. 111: E4551-9. PMID 25313043 DOI: 10.1073/Pnas.1404736111  0.306
2014 Demers JP, Habenstein B, Loquet A, Kumar Vasa S, Giller K, Becker S, Baker D, Lange A, Sgourakis NG. High-resolution structure of the Shigella type-III secretion needle by solid-state NMR and cryo-electron microscopy. Nature Communications. 5: 4976. PMID 25264107 DOI: 10.1038/Ncomms5976  0.308
2014 Vranjkovic O, Gasser PJ, Gerndt CH, Baker DA, Mantsch JR. Stress-induced cocaine seeking requires a beta-2 adrenergic receptor-regulated pathway from the ventral bed nucleus of the stria terminalis that regulates CRF actions in the ventral tegmental area. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 12504-14. PMID 25209288 DOI: 10.1523/Jneurosci.0680-14.2014  0.348
2014 Resch JM, Albano R, Liu X, Hjelmhaug J, Lobner D, Baker DA, Choi S. Augmented cystine-glutamate exchange by pituitary adenylate cyclase-activating polypeptide signaling via the VPAC1 receptor. Synapse (New York, N.Y.). PMID 25066643 DOI: 10.1002/Syn.21772  0.304
2014 King NP, Bale JB, Sheffler W, McNamara DE, Gonen S, Gonen T, Yeates TO, Baker D. Accurate design of co-assembling multi-component protein nanomaterials. Nature. 510: 103-8. PMID 24870237 DOI: 10.1038/Nature13404  0.303
2014 Chen KY, Sun J, Salvo JS, Baker D, Barth P. High-resolution modeling of transmembrane helical protein structures from distant homologues. Plos Computational Biology. 10: e1003636. PMID 24854015 DOI: 10.1371/Journal.Pcbi.1003636  0.346
2014 King C, Garza EN, Mazor R, Linehan JL, Pastan I, Pepper M, Baker D. Removing T-cell epitopes with computational protein design. Proceedings of the National Academy of Sciences of the United States of America. 111: 8577-82. PMID 24843166 DOI: 10.1073/Pnas.1321126111  0.303
2014 Ovchinnikov S, Kamisetty H, Baker D. Robust and accurate prediction of residue-residue interactions across protein interfaces using evolutionary information. Elife. 3: e02030. PMID 24842992 DOI: 10.7554/Elife.02030  0.321
2014 Lutgen V, Resch J, Qualmann K, Raddatz NJ, Panhans C, Olander EM, Kong L, Choi S, Mantsch JR, Baker DA. Behavioral assessment of acute inhibition of system xc (-) in rats. Psychopharmacology. 231: 4637-47. PMID 24828877 DOI: 10.1007/S00213-014-3612-4  0.742
2014 McReynolds JR, Vranjkovic O, Thao M, Baker DA, Makky K, Lim Y, Mantsch JR. Beta-2 adrenergic receptors mediate stress-evoked reinstatement of cocaine-induced conditioned place preference and increases in CRF mRNA in the bed nucleus of the stria terminalis in mice. Psychopharmacology. 231: 3953-63. PMID 24696080 DOI: 10.1007/S00213-014-3535-0  0.302
2014 Khoury GA, Liwo A, Khatib F, Zhou H, Chopra G, Bacardit J, Bortot LO, Faccioli RA, Deng X, He Y, Krupa P, Li J, Mozolewska MA, Sieradzan AK, Smadbeck J, ... Baker D, et al. WeFold: a coopetition for protein structure prediction. Proteins. 82: 1850-68. PMID 24677212 DOI: 10.1002/Prot.24538  0.305
2014 Baker D. Protein folding, structure prediction and design Biochemical Society Transactions. 42: 225-229. PMID 24646222 DOI: 10.1042/Bst20130055  0.333
2014 Liu Y, Tan YL, Zhang X, Bhabha G, Ekiert DC, Genereux JC, Cho Y, Kipnis Y, Bjelic S, Baker D, Kelly JW. Small molecule probes to quantify the functional fraction of a specific protein in a cell with minimal folding equilibrium shifts. Proceedings of the National Academy of Sciences of the United States of America. 111: 4449-54. PMID 24591605 DOI: 10.1073/Pnas.1323268111  0.308
2014 Mao B, Tejero R, Baker D, Montelione GT. Protein NMR structures refined with Rosetta have higher accuracy relative to corresponding X-ray crystal structures. Journal of the American Chemical Society. 136: 1893-906. PMID 24392845 DOI: 10.1021/Ja409845W  0.309
2014 Conway P, Tyka MD, DiMaio F, Konerding DE, Baker D. Relaxation of backbone bond geometry improves protein energy landscape modeling. Protein Science : a Publication of the Protein Society. 23: 47-55. PMID 24265211 DOI: 10.1002/Pro.2389  0.311
2014 Kim DE, Dimaio F, Yu-Ruei Wang R, Song Y, Baker D. One contact for every twelve residues allows robust and accurate topology-level protein structure modeling Proteins: Structure, Function and Bioinformatics. 82: 208-218. PMID 23900763 DOI: 10.1002/Prot.24374  0.319
2014 Lutgen V, Kong L, Kau KS, Madayag A, Mantsch JR, Baker DA. Time course of cocaine-induced behavioral and neurochemical plasticity. Addiction Biology. 19: 529-38. PMID 22970924 DOI: 10.1111/J.1369-1600.2012.00493.X  0.78
2014 Terwilliger TC, DiMaio F, Read RJ, Baker D, Brunger AT, Adams PD, Afonine PV, Hung L. Combining Crystallographic and Structure-Modeling Approaches in Macromolecular Crystallography Biophysical Journal. 106: 34a. DOI: 10.1016/J.Bpj.2013.11.263  0.303
2014 Lai Y, King NP, Sheffler W, McNamara DE, Bale JB, Baker D, Yeates TO. Symmetry-Based Design and Structure of Self-Assembling Protein Cages and Nanomaterials Biophysical Journal. 106: 445a. DOI: 10.1016/J.Bpj.2013.11.2516  0.31
2013 Kamisetty H, Ovchinnikov S, Baker D. Assessing the utility of coevolution-based residue-residue contact predictions in a sequence- and structure-rich era Proceedings of the National Academy of Sciences of the United States of America. 110: 15674-15679. PMID 24009338 DOI: 10.1073/Pnas.1314045110  0.31
2013 Tinberg CE, Khare SD, Dou J, Doyle L, Nelson JW, Schena A, Jankowski W, Kalodimos CG, Johnsson K, Stoddard BL, Baker D. Computational design of ligand-binding proteins with high affinity and selectivity. Nature. 501: 212-6. PMID 24005320 DOI: 10.1038/Nature12443  0.301
2013 van der Schot G, Zhang Z, Vernon R, Shen Y, Vranken WF, Baker D, Bonvin AM, Lange OF. Improving 3D structure prediction from chemical shift data. Journal of Biomolecular Nmr. 57: 27-35. PMID 23912841 DOI: 10.1007/S10858-013-9762-6  0.315
2013 Moal IH, Moretti R, Baker D, Fernández-Recio J. Scoring functions for protein-protein interactions. Current Opinion in Structural Biology. 23: 862-7. PMID 23871100 DOI: 10.1016/J.Sbi.2013.06.017  0.328
2013 Graf EN, Wheeler RA, Baker DA, Ebben AL, Hill JE, McReynolds JR, Robble MA, Vranjkovic O, Wheeler DS, Mantsch JR, Gasser PJ. Corticosterone acts in the nucleus accumbens to enhance dopamine signaling and potentiate reinstatement of cocaine seeking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 11800-10. PMID 23864669 DOI: 10.1523/Jneurosci.1969-13.2013  0.367
2013 Procko E, Hedman R, Hamilton K, Seetharaman J, Fleishman SJ, Su M, Aramini J, Kornhaber G, Hunt JF, Tong L, Montelione GT, Baker D. Computational design of a protein-based enzyme inhibitor. Journal of Molecular Biology. 425: 3563-75. PMID 23827138 DOI: 10.1016/J.Jmb.2013.06.035  0.301
2013 Geibel S, Procko E, Hultgren SJ, Baker D, Waksman G. Structural and energetic basis of folded-protein transport by the FimD usher. Nature. 496: 243-6. PMID 23579681 DOI: 10.1038/Nature12007  0.303
2013 Nivón LG, Moretti R, Baker D. A Pareto-optimal refinement method for protein design scaffolds. Plos One. 8: e59004. PMID 23565140 DOI: 10.1371/Journal.Pone.0059004  0.324
2013 Demers JP, Sgourakis NG, Gupta R, Loquet A, Giller K, Riedel D, Laube B, Kolbe M, Baker D, Becker S, Lange A. The common structural architecture of Shigella flexneri and Salmonella typhimurium type three secretion needles. Plos Pathogens. 9: e1003245. PMID 23555258 DOI: 10.1371/Journal.Ppat.1003245  0.306
2013 Lutgen V, Qualmann K, Resch J, Kong L, Choi S, Baker DA. Reduction in phencyclidine induced sensorimotor gating deficits in the rat following increased system xc⁻ activity in the medial prefrontal cortex. Psychopharmacology. 226: 531-40. PMID 23192314 DOI: 10.1007/S00213-012-2926-3  0.738
2012 Koga N, Tatsumi-Koga R, Liu G, Xiao R, Acton TB, Montelione GT, Baker D. Principles for designing ideal protein structures. Nature. 491: 222-7. PMID 23135467 DOI: 10.1038/Nature11600  0.339
2012 Alon A, Grossman I, Gat Y, Kodali VK, DiMaio F, Mehlman T, Haran G, Baker D, Thorpe C, Fass D. The dynamic disulphide relay of quiescin sulphydryl oxidase. Nature. 488: 414-8. PMID 22801504 DOI: 10.1038/Nature11267  0.302
2012 Bridges R, Lutgen V, Lobner D, Baker DA. Thinking outside the cleft to understand synaptic activity: contribution of the cystine-glutamate antiporter (System xc-) to normal and pathological glutamatergic signaling. Pharmacological Reviews. 64: 780-802. PMID 22759795 DOI: 10.1124/Pr.110.003889  0.746
2012 Lange OF, Rossi P, Sgourakis NG, Song Y, Lee HW, Aramini JM, Ertekin A, Xiao R, Acton TB, Montelione GT, Baker D. Determination of solution structures of proteins up to 40 kDa using CS-Rosetta with sparse NMR data from deuterated samples. Proceedings of the National Academy of Sciences of the United States of America. 109: 10873-8. PMID 22733734 DOI: 10.1073/Pnas.1203013109  0.311
2012 Loquet A, Sgourakis NG, Gupta R, Giller K, Riedel D, Goosmann C, Griesinger C, Kolbe M, Baker D, Becker S, Lange A. Atomic model of the type III secretion system needle Nature. 486: 276-279. PMID 22699623 DOI: 10.1038/Nature11079  0.302
2012 Thompson JM, Sgourakis NG, Liu G, Rossi P, Tang Y, Mills JL, Szyperski T, Montelione GT, Baker D. Accurate protein structure modeling using sparse NMR data and homologous structure information. Proceedings of the National Academy of Sciences of the United States of America. 109: 9875-80. PMID 22665781 DOI: 10.1073/Pnas.1202485109  0.327
2012 Vranjkovic O, Hang S, Baker DA, Mantsch JR. β-adrenergic receptor mediation of stress-induced reinstatement of extinguished cocaine-induced conditioned place preference in mice: roles for β1 and β2 adrenergic receptors. The Journal of Pharmacology and Experimental Therapeutics. 342: 541-51. PMID 22593095 DOI: 10.1124/Jpet.112.193615  0.322
2012 Fleishman SJ, Baker D. Role of the biomolecular energy gap in protein design, structure, and evolution. Cell. 149: 262-73. PMID 22500796 DOI: 10.1016/J.Cell.2012.03.016  0.306
2012 Thyme SB, Baker D, Bradley P. Improved modeling of side-chain--base interactions and plasticity in protein--DNA interface design. Journal of Molecular Biology. 419: 255-74. PMID 22426128 DOI: 10.1016/J.Jmb.2012.03.005  0.315
2012 Lange OF, Baker D. Resolution-adapted recombination of structural features significantly improves sampling in restraint-guided structure calculation. Proteins. 80: 884-95. PMID 22423358 DOI: 10.1002/Prot.23245  0.311
2012 Rosato A, Aramini JM, Arrowsmith C, Bagaria A, Baker D, Cavalli A, Doreleijers JF, Eletsky A, Giachetti A, Guerry P, Gutmanas A, Güntert P, He Y, Herrmann T, Huang YJ, et al. Blind testing of routine, fully automated determination of protein structures from NMR data. Structure (London, England : 1993). 20: 227-36. PMID 22325772 DOI: 10.1016/J.Str.2012.01.002  0.309
2012 Wojdyla JA, Fleishman SJ, Baker D, Kleanthous C. Structure of the ultra-high-affinity colicin E2 DNase--Im2 complex. Journal of Molecular Biology. 417: 79-94. PMID 22306467 DOI: 10.1016/J.Jmb.2012.01.019  0.334
2012 Handl J, Knowles J, Vernon R, Baker D, Lovell SC. The dual role of fragments in fragment-assembly methods for de novo protein structure prediction. Proteins. 80: 490-504. PMID 22095594 DOI: 10.1002/Prot.23215  0.313
2012 Strauch E, Fleishman SJ, Baker D. De Novo Design of Protein Binders: Targeting Human IgG (Fc) Biophysical Journal. 102: 189a. DOI: 10.1016/J.Bpj.2011.11.1033  0.322
2011 Gilski M, Kazmierczyk M, Krzywda S, Zábranská H, Cooper S, Popović Z, Khatib F, DiMaio F, Thompson J, Baker D, Pichová I, Jaskolski M. High-resolution structure of a retroviral protease folded as a monomer. Acta Crystallographica. Section D, Biological Crystallography. 67: 907-14. PMID 22101816 DOI: 10.1107/S0907444911035943  0.34
2011 Azoitei ML, Correia BE, Ban YE, Carrico C, Kalyuzhniy O, Chen L, Schroeter A, Huang PS, McLellan JS, Kwong PD, Baker D, Strong RK, Schief WR. Computation-guided backbone grafting of a discontinuous motif onto a protein scaffold. Science (New York, N.Y.). 334: 373-6. PMID 22021856 DOI: 10.1126/Science.1209368  0.301
2011 Fleishman SJ, Whitehead TA, Strauch EM, Corn JE, Qin S, Zhou HX, Mitchell JC, Demerdash ON, Takeda-Shitaka M, Terashi G, Moal IH, Li X, Bates PA, Zacharias M, Park H, ... Baker D, et al. Community-wide assessment of protein-interface modeling suggests improvements to design methodology. Journal of Molecular Biology. 414: 289-302. PMID 22001016 DOI: 10.1016/J.Jmb.2011.09.031  0.311
2011 Fleishman SJ, Corn JE, Strauch EM, Whitehead TA, Karanicolas J, Baker D. Hotspot-centric de novo design of protein binders. Journal of Molecular Biology. 413: 1047-62. PMID 21945116 DOI: 10.1016/J.Jmb.2011.09.001  0.304
2011 Khatib F, DiMaio F, Cooper S, Kazmierczyk M, Gilski M, Krzywda S, Zabranska H, Pichova I, Thompson J, Popović Z, Jaskolski M, Baker D. Crystal structure of a monomeric retroviral protease solved by protein folding game players. Nature Structural & Molecular Biology. 18: 1175-7. PMID 21926992 DOI: 10.1038/Nsmb.2119  0.319
2011 Huang PS, Ban YE, Richter F, Andre I, Vernon R, Schief WR, Baker D. RosettaRemodel: a generalized framework for flexible backbone protein design. Plos One. 6: e24109. PMID 21909381 DOI: 10.1371/Journal.Pone.0024109  0.301
2011 Wang RYR, Han Y, Krassovsky K, Sheffler W, Tyka M, Baker D. Modeling disordered regions in proteins using Rosetta Plos One. 6. PMID 21829444 DOI: 10.1371/Journal.Pone.0022060  0.301
2011 Blacktop JM, Seubert C, Baker DA, Ferda N, Lee G, Graf EN, Mantsch JR. Augmented cocaine seeking in response to stress or CRF delivered into the ventral tegmental area following long-access self-administration is mediated by CRF receptor type 1 but not CRF receptor type 2. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 11396-403. PMID 21813699 DOI: 10.1523/Jneurosci.1393-11.2011  0.366
2011 DiMaio F, Leaver-Fay A, Bradley P, Baker D, André I. Modeling symmetric macromolecular structures in Rosetta3. Plos One. 6: e20450. PMID 21731614 DOI: 10.1371/Journal.Pone.0020450  0.31
2011 Thompson J, Baker D. Incorporation of evolutionary information into Rosetta comparative modeling. Proteins. 79: 2380-8. PMID 21638331 DOI: 10.1002/Prot.23046  0.33
2011 DiMaio F, Terwilliger TC, Read RJ, Wlodawer A, Oberdorfer G, Wagner U, Valkov E, Alon A, Fass D, Axelrod HL, Das D, Vorobiev SM, Iwaï H, Pokkuluri PR, Baker D. Improved molecular replacement by density- and energy-guided protein structure optimization. Nature. 473: 540-3. PMID 21532589 DOI: 10.1038/Nature09964  0.329
2011 Sgourakis NG, Lange OF, DiMaio F, André I, Fitzkee NC, Rossi P, Montelione GT, Bax A, Baker D. Determination of the structures of symmetric protein oligomers from NMR chemical shifts and residual dipolar couplings. Journal of the American Chemical Society. 133: 6288-98. PMID 21466200 DOI: 10.1021/Ja111318M  0.324
2011 Karanicolas J, Corn JE, Chen I, Joachimiak LA, Dym O, Peck SH, Albeck S, Unger T, Hu W, Liu G, Delbecq S, Montelione GT, Spiegel CP, Liu DR, Baker D. A de novo protein binding pair by computational design and directed evolution. Molecular Cell. 42: 250-60. PMID 21458342 DOI: 10.1016/J.Molcel.2011.03.010  0.319
2011 Fleishman SJ, Khare SD, Koga N, Baker D. Restricted sidechain plasticity in the structures of native proteins and complexes. Protein Science : a Publication of the Protein Society. 20: 753-7. PMID 21432939 DOI: 10.1002/Pro.604  0.324
2011 Kellogg EH, Leaver-Fay A, Baker D. Role of conformational sampling in computing mutation-induced changes in protein structure and stability. Proteins. 79: 830-8. PMID 21287615 DOI: 10.1002/Prot.22921  0.309
2011 Chen DH, Baker ML, Hryc CF, DiMaio F, Jakana J, Wu W, Dougherty M, Haase-Pettingell C, Schmid MF, Jiang W, Baker D, King JA, Chiu W. Structural basis for scaffolding-mediated assembly and maturation of a dsDNA virus. Proceedings of the National Academy of Sciences of the United States of America. 108: 1355-60. PMID 21220301 DOI: 10.1073/Pnas.1015739108  0.324
2011 Amen SL, Piacentine LB, Ahmad ME, Li SJ, Mantsch JR, Risinger RC, Baker DA. Repeated N-acetyl cysteine reduces cocaine seeking in rodents and craving in cocaine-dependent humans. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 871-8. PMID 21160464 DOI: 10.1038/Npp.2010.226  0.385
2011 Tyka MD, Keedy DA, André I, Dimaio F, Song Y, Richardson DC, Richardson JS, Baker D. Alternate states of proteins revealed by detailed energy landscape mapping. Journal of Molecular Biology. 405: 607-18. PMID 21073878 DOI: 10.1016/J.Jmb.2010.11.008  0.323
2010 Weerapana E, Wang C, Simon GM, Richter F, Khare S, Dillon MB, Bachovchin DA, Mowen K, Baker D, Cravatt BF. Quantitative reactivity profiling predicts functional cysteines in proteomes. Nature. 468: 790-5. PMID 21085121 DOI: 10.1038/Nature09472  0.311
2010 Tang Y, Schneider WM, Shen Y, Raman S, Inouye M, Baker D, Roth MJ, Montelione GT. Fully automated high-quality NMR structure determination of small (2)H-enriched proteins. Journal of Structural and Functional Genomics. 11: 223-32. PMID 20734145 DOI: 10.1007/S10969-010-9095-6  0.316
2010 Sheffler W, Baker D. RosettaHoles2: A volumetric packing measure for protein structure refinement and validation Protein Science. 19: 1991-1995. PMID 20665689 DOI: 10.1002/Pro.458  0.315
2010 Mantsch JR, Weyer A, Vranjkovic O, Beyer CE, Baker DA, Caretta H. Involvement of noradrenergic neurotransmission in the stress- but not cocaine-induced reinstatement of extinguished cocaine-induced conditioned place preference in mice: role for β-2 adrenergic receptors. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 2165-78. PMID 20613718 DOI: 10.1038/Npp.2010.86  0.36
2010 Meenan NA, Sharma A, Fleishman SJ, Macdonald CJ, Morel B, Boetzel R, Moore GR, Baker D, Kleanthous C. The structural and energetic basis for high selectivity in a high-affinity protein-protein interaction. Proceedings of the National Academy of Sciences of the United States of America. 107: 10080-5. PMID 20479265 DOI: 10.1073/Pnas.0910756107  0.313
2010 Zelter A, Hoopmann MR, Vernon R, Baker D, MacCoss MJ, Davis TN. Isotope signatures allow identification of chemically cross-linked peptides by mass spectrometry: A novel method to determine interresidue distances in protein structures through cross-linking Journal of Proteome Research. 9: 3583-3589. PMID 20476776 DOI: 10.1021/Pr1001115  0.308
2010 Raman S, Lange OF, Rossi P, Tyka M, Wang X, Aramini J, Liu G, Ramelot TA, Eletsky A, Szyperski T, Kennedy MA, Prestegard J, Montelione GT, Baker D. NMR structure determination for larger proteins using backbone-only data. Science (New York, N.Y.). 327: 1014-8. PMID 20133520 DOI: 10.1126/Science.1183649  0.309
2010 Wang C, Vernon R, Lange O, Tyka M, Baker D. Prediction of structures of zinc-binding proteins through explicit modeling of metal coordination geometry. Protein Science : a Publication of the Protein Society. 19: 494-506. PMID 20054832 DOI: 10.1002/Pro.327  0.311
2010 Madayag A, Kau KS, Lobner D, Mantsch JR, Wisniewski S, Baker DA. Drug-induced plasticity contributing to heightened relapse susceptibility: neurochemical changes and augmented reinstatement in high-intake rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 210-7. PMID 20053903 DOI: 10.1523/Jneurosci.1342-09.2010  0.779
2010 Shen Y, Bryan PN, He Y, Orban J, Baker D, Bax A. De novo structure generation using chemical shifts for proteins with high-sequence identity but different folds. Protein Science : a Publication of the Protein Society. 19: 349-56. PMID 19998407 DOI: 10.1002/Pro.303  0.318
2009 Das R, André I, Shen Y, Wu Y, Lemak A, Bansal S, Arrowsmith CH, Szyperski T, Baker D. Simultaneous prediction of protein folding and docking at high resolution. Proceedings of the National Academy of Sciences of the United States of America. 106: 18978-83. PMID 19864631 DOI: 10.1073/Pnas.0904407106  0.317
2009 Kidd BA, Baker D, Thomas WE. Computation of conformational coupling in allosteric proteins. Plos Computational Biology. 5: e1000484. PMID 19714199 DOI: 10.1371/Journal.Pcbi.1000484  0.322
2009 Kim DE, Blum B, Bradley P, Baker D. Sampling bottlenecks in de novo protein structure prediction. Journal of Molecular Biology. 393: 249-60. PMID 19646450 DOI: 10.1016/J.Jmb.2009.07.063  0.321
2009 Havranek JJ, Baker D. Motif-directed flexible backbone design of functional interactions. Protein Science : a Publication of the Protein Society. 18: 1293-305. PMID 19472357 DOI: 10.1002/Pro.142  0.315
2009 Murphy PM, Bolduc JM, Gallaher JL, Stoddard BL, Baker D. Alteration of enzyme specificity by computational loop remodeling and design. Proceedings of the National Academy of Sciences of the United States of America. 106: 9215-20. PMID 19470646 DOI: 10.1073/Pnas.0811070106  0.317
2009 Ashworth J, Baker D. Assessment of the optimization of affinity and specificity at protein-DNA interfaces. Nucleic Acids Research. 37: e73. PMID 19389725 DOI: 10.1093/Nar/Gkp242  0.302
2009 Barth P, Wallner B, Baker D. Prediction of membrane protein structures with complex topologies using limited constraints. Proceedings of the National Academy of Sciences of the United States of America. 106: 1409-14. PMID 19190187 DOI: 10.1073/Pnas.0808323106  0.327
2009 Sheffler W, Baker D. RosettaHoles: Rapid assessment of protein core packing for structure prediction, refinement, design, and validation Protein Science. 18: 229-239. PMID 19177366 DOI: 10.1002/Pro.8  0.312
2009 Shen Y, Vernon R, Baker D, Bax A. De novo protein structure generation from incomplete chemical shift assignments. Journal of Biomolecular Nmr. 43: 63-78. PMID 19034676 DOI: 10.1007/S10858-008-9288-5  0.301
2008 Kau KS, Madayag A, Mantsch JR, Grier MD, Abdulhameed O, Baker DA. Blunted cystine-glutamate antiporter function in the nucleus accumbens promotes cocaine-induced drug seeking. Neuroscience. 155: 530-7. PMID 18601982 DOI: 10.1016/J.Neuroscience.2008.06.010  0.405
2008 Keeble AH, Joachimiak LA, Maté MJ, Meenan N, Kirkpatrick N, Baker D, Kleanthous C. Experimental and computational analyses of the energetic basis for dual recognition of immunity proteins by colicin endonucleases. Journal of Molecular Biology. 379: 745-59. PMID 18471830 DOI: 10.1016/J.Jmb.2008.03.055  0.315
2008 Das R, Baker D. Macromolecular modeling with rosetta. Annual Review of Biochemistry. 77: 363-82. PMID 18410248 DOI: 10.1146/Annurev.Biochem.77.062906.171838  0.318
2008 Shen Y, Lange O, Delaglio F, Rossi P, Aramini JM, Liu G, Eletsky A, Wu Y, Singarapu KK, Lemak A, Ignatchenko A, Arrowsmith CH, Szyperski T, Montelione GT, Baker D, et al. Consistent blind protein structure generation from NMR chemical shift data. Proceedings of the National Academy of Sciences of the United States of America. 105: 4685-90. PMID 18326625 DOI: 10.1073/Pnas.0800256105  0.32
2008 Mantsch JR, Baker DA, Francis DM, Katz ES, Hoks MA, Serge JP. Stressor- and corticotropin releasing factor-induced reinstatement and active stress-related behavioral responses are augmented following long-access cocaine self-administration by rats. Psychopharmacology. 195: 591-603. PMID 17899015 DOI: 10.1007/S00213-007-0950-5  0.349
2008 Baker DA, Madayag A, Kristiansen LV, Meador-Woodruff JH, Haroutunian V, Raju I. Contribution of cystine-glutamate antiporters to the psychotomimetic effects of phencyclidine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 1760-72. PMID 17728701 DOI: 10.1038/Sj.Npp.1301532  0.764
2008 Mantsch JR, Baker DA, Serge JP, Hoks MA, Francis DM, Katz ES. Surgical adrenalectomy with diurnal corticosterone replacement slows escalation and prevents the augmentation of cocaine-induced reinstatement in rats self-administering cocaine under long-access conditions. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 814-26. PMID 17534378 DOI: 10.1038/Sj.Npp.1301464  0.352
2008 Raman S, Qian B, Baker D, Walker RC. Advances in Rosetta protein structure prediction on massively parallel systems Ibm Journal of Research and Development. 52: 7-18. DOI: 10.1147/Rd.521.0007  0.33
2007 Madayag A, Lobner D, Kau KS, Mantsch JR, Abdulhameed O, Hearing M, Grier MD, Baker DA. Repeated N-acetylcysteine administration alters plasticity-dependent effects of cocaine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 13968-76. PMID 18094234 DOI: 10.1523/Jneurosci.2808-07.2007  0.783
2007 André I, Bradley P, Wang C, Baker D. Prediction of the structure of symmetrical protein assemblies. Proceedings of the National Academy of Sciences of the United States of America. 104: 17656-61. PMID 17978193 DOI: 10.1073/Pnas.0702626104  0.323
2007 Qian B, Raman S, Das R, Bradley P, McCoy AJ, Read RJ, Baker D. High-resolution structure prediction and the crystallographic phase problem. Nature. 450: 259-64. PMID 17934447 DOI: 10.1038/Nature06249  0.32
2007 Barth P, Schonbrun J, Baker D. Toward high-resolution prediction and design of transmembrane helical protein structures. Proceedings of the National Academy of Sciences of the United States of America. 104: 15682-7. PMID 17905872 DOI: 10.1073/Pnas.0702515104  0.317
2007 Wang C, Bradley P, Baker D. Protein-protein docking with backbone flexibility. Journal of Molecular Biology. 373: 503-19. PMID 17825317 DOI: 10.1016/J.Jmb.2007.07.050  0.325
2007 Mantsch JR, Cullinan WE, Tang LC, Baker DA, Katz ES, Hoks MA, Ziegler DR. Daily cocaine self-administration under long-access conditions augments restraint-induced increases in plasma corticosterone and impairs glucocorticoid receptor-mediated negative feedback in rats. Brain Research. 1167: 101-11. PMID 17689506 DOI: 10.1016/J.Brainres.2007.05.080  0.342
2007 Wang C, Schueler-Furman O, Andre I, London N, Fleishman SJ, Bradley P, Qian B, Baker D. RosettaDock in CAPRI rounds 6-12. Proteins. 69: 758-63. PMID 17671979 DOI: 10.1002/Prot.21684  0.338
2007 Malmström L, Riffle M, Strauss CEM, Chivian D, Davis TN, Bonneau R, Baker D. Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology Plos Biology. 5. PMID 17373854 DOI: 10.1371/Journal.Pbio.0050076  0.314
2007 Mantsch JR, Li SJ, Risinger R, Awad S, Katz E, Baker DA, Yang Z. Levo-tetrahydropalmatine attenuates cocaine self-administration and cocaine-induced reinstatement in rats. Psychopharmacology. 192: 581-91. PMID 17361394 DOI: 10.1007/S00213-007-0754-7  0.341
2007 Watters AL, Deka P, Corrent C, Callender D, Varani G, Sosnick T, Baker D. The highly cooperative folding of small naturally occurring proteins is likely the result of natural selection. Cell. 128: 613-24. PMID 17289578 DOI: 10.1016/J.Cell.2006.12.042  0.313
2007 Dantas G, Corrent C, Reichow SL, Havranek JJ, Eletr ZM, Isern NG, Kuhlman B, Varani G, Merritt EA, Baker D. High-resolution structural and thermodynamic analysis of extreme stabilization of human procarboxypeptidase by computational protein design. Journal of Molecular Biology. 366: 1209-21. PMID 17196978 DOI: 10.1016/J.Jmb.2006.11.080  0.323
2007 Wollacott AM, Zanghellini A, Murphy P, Baker D. Prediction of structures of multidomain proteins from structures of the individual domains. Protein Science : a Publication of the Protein Society. 16: 165-75. PMID 17189483 DOI: 10.1110/Ps.062270707  0.313
2006 Baker ML, Jiang W, Wedemeyer WJ, Rixon FJ, Baker D, Chiu W. Ab initio modeling of the herpesvirus VP26 core domain assessed by CryoEM density. Plos Computational Biology. 2: e146. PMID 17069457 DOI: 10.1371/Journal.Pcbi.0020146  0.315
2006 Meiler J, Baker D. ROSETTALIGAND: protein-small molecule docking with full side-chain flexibility. Proteins. 65: 538-48. PMID 16972285 DOI: 10.1002/Prot.21086  0.312
2006 Chivian D, Baker D. Homology modeling using parametric alignment ensemble generation with consensus and energy-based model selection Nucleic Acids Research. 34. PMID 16971460 DOI: 10.1093/Nar/Gkl480  0.308
2006 Dantas G, Watters AL, Lunde BM, Eletr ZM, Isern NG, Roseman T, Lipfert J, Doniach S, Tompa M, Kuhlman B, Stoddard BL, Varani G, Baker D. Mis-translation of a computationally designed protein yields an exceptionally stable homodimer: implications for protein engineering and evolution. Journal of Molecular Biology. 362: 1004-24. PMID 16949611 DOI: 10.1016/J.Jmb.2006.07.092  0.34
2006 Joachimiak LA, Kortemme T, Stoddard BL, Baker D. Computational design of a new hydrogen bond network and at least a 300-fold specificity switch at a protein-protein interface. Journal of Molecular Biology. 361: 195-208. PMID 16831445 DOI: 10.1016/J.Jmb.2006.05.022  0.314
2006 Ashworth J, Havranek JJ, Duarte CM, Sussman D, Monnat RJ, Stoddard BL, Baker D. Computational redesign of endonuclease DNA binding and cleavage specificity. Nature. 441: 656-9. PMID 16738662 DOI: 10.1038/Nature04818  0.301
2006 Dobson N, Dantas G, Baker D, Varani G. High-resolution structural validation of the computational redesign of human U1A protein. Structure (London, England : 1993). 14: 847-56. PMID 16698546 DOI: 10.1016/J.Str.2006.02.011  0.328
2006 Misura KM, Chivian D, Rohl CA, Kim DE, Baker D. Physically realistic homology models built with ROSETTA can be more accurate than their templates. Proceedings of the National Academy of Sciences of the United States of America. 103: 5361-6. PMID 16567638 DOI: 10.1073/Pnas.0509355103  0.302
2006 Arakaki T, Le Trong I, Phizicky E, Quartley E, DeTitta G, Luft J, Lauricella A, Anderson L, Kalyuzhniy O, Worthey E, Myler PJ, Kim D, Baker D, Hol WG, Merritt EA. Structure of Lmaj006129AAA, a hypothetical protein from Leishmania major. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 62: 175-9. PMID 16511295 DOI: 10.1107/S1744309106005902  0.318
2006 Baker DA, Kalivas PW. Chapter 1.3 Insights into glutamate physiology: contribution of studies utilizing in vivo microdialysis Handbook of Behavioral Neuroscience. 16: 33-46. DOI: 10.1016/S1569-7339(06)16003-8  0.486
2005 Schueler-Furman O, Wang C, Bradley P, Misura K, Baker D. Progress in modeling of protein structures and interactions. Science (New York, N.Y.). 310: 638-42. PMID 16254179 DOI: 10.1126/Science.1112160  0.304
2005 Cheng G, Qian B, Samudrala R, Baker D. Improvement in protein functional site prediction by distinguishing structural and functional constraints on protein family evolution using computational design. Nucleic Acids Research. 33: 5861-7. PMID 16224101 DOI: 10.1093/Nar/Gki894  0.312
2005 Bradley P, Misura KM, Baker D. Toward high-resolution de novo structure prediction for small proteins. Science (New York, N.Y.). 309: 1868-71. PMID 16166519 DOI: 10.1126/Science.1113801  0.321
2005 Schueler-Furman O, Wang C, Baker D. Progress in protein-protein docking: atomic resolution predictions in the CAPRI experiment using RosettaDock with an improved treatment of side-chain flexibility. Proteins. 60: 187-94. PMID 15981249 DOI: 10.1002/Prot.20556  0.307
2005 Wang C, Schueler-Furman O, Baker D. Improved side-chain modeling for protein-protein docking. Protein Science : a Publication of the Protein Society. 14: 1328-39. PMID 15802647 DOI: 10.1110/Ps.041222905  0.315
2005 Meiler J, Baker D. The fumarate sensor DcuS: progress in rapid protein fold elucidation by combining protein structure prediction methods with NMR spectroscopy. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 173: 310-6. PMID 15780923 DOI: 10.1016/J.Jmr.2004.11.031  0.322
2005 Misura KM, Baker D. Progress and challenges in high-resolution refinement of protein structure models. Proteins. 59: 15-29. PMID 15690346 DOI: 10.1002/Prot.20376  0.325
2005 Saunders CT, Baker D. Recapitulation of protein family divergence using flexible backbone protein design. Journal of Molecular Biology. 346: 631-44. PMID 15670610 DOI: 10.1016/J.Jmb.2004.11.062  0.313
2005 Jiang L, Kuhlman B, Kortemme T, Baker D. A "solvated rotamer" approach to modeling water-mediated hydrogen bonds at protein-protein interfaces. Proteins. 58: 893-904. PMID 15651050 DOI: 10.1002/Prot.20347  0.306
2005 Baker DA, Kalivas PW. Sensitization and relapse dopamine-glutamate interactions Dopamine and Glutamate in Psychiatric Disorders. 355-369. DOI: 10.1007/978-1-59259-852-6_15  0.411
2004 Havranek JJ, Duarte CM, Baker D. A simple physical model for the prediction and design of protein-DNA interactions. Journal of Molecular Biology. 344: 59-70. PMID 15504402 DOI: 10.1016/J.Jmb.2004.09.029  0.312
2004 Misura KM, Morozov AV, Baker D. Analysis of anisotropic side-chain packing in proteins and application to high-resolution structure prediction. Journal of Molecular Biology. 342: 651-64. PMID 15327962 DOI: 10.1016/J.Jmb.2004.07.038  0.329
2004 Kim DE, Chivian D, Baker D. Protein structure prediction and analysis using the Robetta server. Nucleic Acids Research. 32: W526-31. PMID 15215442 DOI: 10.1093/Nar/Gkh468  0.334
2004 Rohl CA, Strauss CE, Chivian D, Baker D. Modeling structurally variable regions in homologous proteins with rosetta. Proteins. 55: 656-77. PMID 15103629 DOI: 10.1002/Prot.10629  0.33
2004 Kuhlman B, Baker D. Exploring folding free energy landscapes using computational protein design. Current Opinion in Structural Biology. 14: 89-95. PMID 15102454 DOI: 10.1016/J.Sbi.2004.01.002  0.332
2004 Watters AL, Baker D. Searching for folded proteins in vitro and in silico. European Journal of Biochemistry / Febs. 271: 1615-22. PMID 15096200 DOI: 10.1111/J.1432-1033.2004.04072.X  0.323
2004 Scalley-Kim M, Baker D. Characterization of the folding energy landscapes of computer generated proteins suggests high folding free energy barriers and cooperativity may be consequences of natural selection. Journal of Molecular Biology. 338: 573-83. PMID 15081814 DOI: 10.1016/J.Jmb.2004.02.055  0.313
2004 Rohl CA, Strauss CE, Misura KM, Baker D. Protein structure prediction using Rosetta. Methods in Enzymology. 383: 66-93. PMID 15063647 DOI: 10.1016/S0076-6879(04)83004-0  0.33
2004 Kortemme T, Baker D. Computational design of protein-protein interactions. Current Opinion in Chemical Biology. 8: 91-7. PMID 15036162 DOI: 10.1016/J.Cbpa.2003.12.008  0.314
2004 Kortemme T, Joachimiak LA, Bullock AN, Schuler AD, Stoddard BL, Baker D. Computational redesign of protein-protein interaction specificity. Nature Structural & Molecular Biology. 11: 371-9. PMID 15034550 DOI: 10.1038/Nsmb749  0.316
2004 Ginalski K, Rychlewski L, Baker D, Grishin NV. Protein structure prediction for the male-specific region of the human Y chromosome. Proceedings of the National Academy of Sciences of the United States of America. 101: 2305-10. PMID 14983005 DOI: 10.1073/Pnas.0306306101  0.313
2004 Kortemme T, Kim DE, Baker D. Computational alanine scanning of protein-protein interfaces. Science's Stke : Signal Transduction Knowledge Environment. 2004: pl2. PMID 14872095 DOI: 10.1126/Stke.2192004Pl2  0.33
2003 Hazbun TR, Malmström L, Anderson S, Graczyk BJ, Fox B, Riffle M, Sundin BA, Aranda JD, McDonald WH, Chiu CH, Snydsman BE, Bradley P, Muller EG, Fields S, Baker D, et al. Assigning function to yeast proteins by integration of technologies. Molecular Cell. 12: 1353-65. PMID 14690591 DOI: 10.1016/S1097-2765(03)00476-3  0.306
2003 Moran MM, Melendez R, Baker D, Kalivas PW, Seamans JK. Cystine/glutamate antiporter regulation of vesicular glutamate release. Annals of the New York Academy of Sciences. 1003: 445-7. PMID 14684484 DOI: 10.1196/Annals.1300.048  0.463
2003 Baker DA, McFarland K, Lake RW, Shen H, Toda S, Kalivas PW. N-acetyl cysteine-induced blockade of cocaine-induced reinstatement. Annals of the New York Academy of Sciences. 1003: 349-51. PMID 14684458 DOI: 10.1196/Annals.1300.023  0.465
2003 Kalivas PW, McFarland K, Bowers S, Szumlinski K, Xi ZX, Baker D. Glutamate transmission and addiction to cocaine. Annals of the New York Academy of Sciences. 1003: 169-75. PMID 14684444 DOI: 10.1196/Annals.1300.009  0.515
2003 Meiler J, Baker D. Rapid protein fold determination using unassigned NMR data. Proceedings of the National Academy of Sciences of the United States of America. 100: 15404-9. PMID 14668443 DOI: 10.1073/Pnas.2434121100  0.322
2003 Kuhlman B, Dantas G, Ireton GC, Varani G, Stoddard BL, Baker D. Design of a novel globular protein fold with atomic-level accuracy. Science (New York, N.Y.). 302: 1364-8. PMID 14631033 DOI: 10.1126/Science.1089427  0.333
2003 Xi ZX, Shen H, Baker DA, Kalivas PW. Inhibition of non-vesicular glutamate release by group III metabotropic glutamate receptors in the nucleus accumbens. Journal of Neurochemistry. 87: 1204-12. PMID 14622100 DOI: 10.1046/J.1471-4159.2003.02093.X  0.412
2003 Chivian D, Kim DE, Malmström L, Bradley P, Robertson T, Murphy P, Strauss CE, Bonneau R, Rohl CA, Baker D. Automated prediction of CASP-5 structures using the Robetta server. Proteins. 53: 524-33. PMID 14579342 DOI: 10.1002/Prot.10529  0.306
2003 Bradley P, Chivian D, Meiler J, Misura KM, Rohl CA, Schief WR, Wedemeyer WJ, Schueler-Furman O, Murphy P, Schonbrun J, Strauss CE, Baker D. Rosetta predictions in CASP5: successes, failures, and prospects for complete automation. Proteins. 53: 457-68. PMID 14579334 DOI: 10.1002/Prot.10552  0.315
2003 Meiler J, Baker D. Coupled prediction of protein secondary and tertiary structure. Proceedings of the National Academy of Sciences of the United States of America. 100: 12105-10. PMID 14528006 DOI: 10.1073/Pnas.1831973100  0.302
2003 Sadreyev RI, Baker D, Grishin NV. Profile-profile comparisons by COMPASS predict intricate homologies between protein families. Protein Science : a Publication of the Protein Society. 12: 2262-72. PMID 14500884 DOI: 10.1110/Ps.03197403  0.312
2003 Dantas G, Kuhlman B, Callender D, Wong M, Baker D. A large scale test of computational protein design: folding and stability of nine completely redesigned globular proteins. Journal of Molecular Biology. 332: 449-60. PMID 12948494 DOI: 10.1016/S0022-2836(03)00888-X  0.333
2003 Tsai J, Bonneau R, Morozov AV, Kuhlman B, Rohl CA, Baker D. An improved protein decoy set for testing energy functions for protein structure prediction. Proteins. 53: 76-87. PMID 12945051 DOI: 10.1002/Prot.10454  0.317
2003 Ivankov DN, Garbuzynskiy SO, Alm E, Plaxco KW, Baker D, Finkelstein AV. Contact order revisited: influence of protein size on the folding rate. Protein Science : a Publication of the Protein Society. 12: 2057-62. PMID 12931003 DOI: 10.1110/Ps.0302503  0.301
2003 Gray JJ, Moughon S, Wang C, Schueler-Furman O, Kuhlman B, Rohl CA, Baker D. Protein-protein docking with simultaneous optimization of rigid-body displacement and side-chain conformations. Journal of Molecular Biology. 331: 281-99. PMID 12875852 DOI: 10.1016/S0022-2836(03)00670-3  0.331
2003 Kinch LN, Baker D, Grishin NV. Deciphering a novel thioredoxin-like fold family. Proteins. 52: 323-31. PMID 12866046 DOI: 10.1002/Prot.10425  0.31
2003 Schueler-Furman O, Baker D. Conserved residue clustering and protein structure prediction. Proteins. 52: 225-35. PMID 12833546 DOI: 10.1002/Prot.10365  0.312
2003 Baker DA, McFarland K, Lake RW, Shen H, Tang XC, Toda S, Kalivas PW. Neuroadaptations in cystine-glutamate exchange underlie cocaine relapse. Nature Neuroscience. 6: 743-9. PMID 12778052 DOI: 10.1038/Nn1069  0.507
2003 Petzold A, Baker D, Pryce G, Keir G, Thompson EJ, Giovannoni G. Quantification of neurodegeneration by measurement of brain-specific proteins. Journal of Neuroimmunology. 138: 45-8. PMID 12742652 DOI: 10.1016/S0165-5728(03)00092-4  0.306
2003 Chivian D, Robertson T, Bonneau R, Baker D. Ab initio methods Methods of Biochemical Analysis. 44: 547-557. PMID 12647404 DOI: 10.1002/0471721204.Ch27  0.301
2003 Kortemme T, Morozov AV, Baker D. An orientation-dependent hydrogen bonding potential improves prediction of specificity and structure for proteins and protein-protein complexes. Journal of Molecular Biology. 326: 1239-59. PMID 12589766 DOI: 10.1016/S0022-2836(03)00021-4  0.307
2003 Kalivas PW, Toda S, Bowers MS, Baker DA, Ghasemzadeh MB. The temporal sequence of changes in gene expression by drugs of abuse. Methods in Molecular Medicine. 79: 3-11. PMID 12506686 DOI: 10.1385/1-59259-358-5:03  0.36
2002 Baker D. Progress in AB Initio Protein Structure Prediction. The Scientific World Journal. 2: 31-31. PMID 29973789 DOI: 10.1100/Tsw.2002.15  0.342
2002 Nauli S, Kuhlman B, Le Trong I, Stenkamp RE, Teller D, Baker D. Crystal structures and increased stabilization of the protein G variants with switched folding pathways NuG1 and NuG2. Protein Science : a Publication of the Protein Society. 11: 2924-31. PMID 12441390 DOI: 10.1110/Ps.0216902  0.317
2002 Chevalier BS, Kortemme T, Chadsey MS, Baker D, Monnat RJ, Stoddard BL. Design, activity, and structure of a highly specific artificial endonuclease. Molecular Cell. 10: 895-905. PMID 12419232 DOI: 10.1016/S1097-2765(02)00690-1  0.312
2002 Xi ZX, Ramamoorthy S, Baker DA, Shen H, Samuvel DJ, Kalivas PW. Modulation of group II metabotropic glutamate receptor signaling by chronic cocaine. The Journal of Pharmacology and Experimental Therapeutics. 303: 608-15. PMID 12388642 DOI: 10.1124/Jpet.102.039735  0.566
2002 Baker DA, Xi ZX, Shen H, Swanson CJ, Kalivas PW. The origin and neuronal function of in vivo nonsynaptic glutamate. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 9134-41. PMID 12388621 DOI: 10.1523/Jneurosci.22-20-09134.2002  0.654
2002 Kortemme T, Baker D. A simple physical model for binding energy hot spots in protein-protein complexes. Proceedings of the National Academy of Sciences of the United States of America. 99: 14116-21. PMID 12381794 DOI: 10.1073/Pnas.202485799  0.318
2002 Baker DA, Shen H, Kalivas PW. Cystine/glutamate exchange serves as the source for extracellular glutamate: modifications by repeated cocaine administration. Amino Acids. 23: 161-2. PMID 12373531 DOI: 10.1007/s00726-001-0122-6  0.499
2002 Alm E, Morozov AV, Kortemme T, Baker D. Simple physical models connect theory and experiment in protein folding kinetics. Journal of Molecular Biology. 322: 463-76. PMID 12217703 DOI: 10.1016/S0022-2836(02)00706-4  0.316
2002 Bonneau R, Strauss CE, Rohl CA, Chivian D, Bradley P, Malmström L, Robertson T, Baker D. De novo prediction of three-dimensional structures for major protein families. Journal of Molecular Biology. 322: 65-78. PMID 12215415 DOI: 10.1016/S0022-2836(02)00698-8  0.325
2002 Bonneau R, Ruczinski I, Tsai J, Baker D. Contact order and ab initio protein structure prediction. Protein Science : a Publication of the Protein Society. 11: 1937-44. PMID 12142448 DOI: 10.1110/Ps.3790102  0.323
2002 Schonbrun J, Wedemeyer WJ, Baker D. Protein structure prediction in 2002. Current Opinion in Structural Biology. 12: 348-54. PMID 12127454 DOI: 10.1016/S0959-440X(02)00336-6  0.318
2002 Ruczinski I, Kooperberg C, Bonneau R, Baker D. Distributions of beta sheets in proteins with application to structure prediction Proteins: Structure, Function and Genetics. 48: 85-97. PMID 12012340 DOI: 10.1002/Prot.10123  0.308
2002 Walters CE, Pryce G, Hankey DJ, Sebti SM, Hamilton AD, Baker D, Greenwood J, Adamson P. Inhibition of Rho GTPases with protein prenyltransferase inhibitors prevents leukocyte recruitment to the central nervous system and attenuates clinical signs of disease in an animal model of multiple sclerosis. Journal of Immunology (Baltimore, Md. : 1950). 168: 4087-94. PMID 11937568 DOI: 10.4049/Jimmunol.168.8.4087  0.307
2002 Rohl CA, Baker D. De novo determination of protein backbone structure from residual dipolar couplings using Rosetta. Journal of the American Chemical Society. 124: 2723-9. PMID 11890823 DOI: 10.1021/Ja016880E  0.338
2002 Larson SM, Ruczinski I, Davidson AR, Baker D, Plaxco KW. Residues participating in the protein folding nucleus do not exhibit preferential evolutionary conservation. Journal of Molecular Biology. 316: 225-33. PMID 11851333 DOI: 10.1006/Jmbi.2001.5344  0.322
2002 Kuhlman B, O'Neill JW, Kim DE, Zhang KY, Baker D. Accurate computer-based design of a new backbone conformation in the second turn of protein L. Journal of Molecular Biology. 315: 471-7. PMID 11786026 DOI: 10.1006/Jmbi.2001.5229  0.315
2002 Xi ZX, Baker DA, Shen H, Carson DS, Kalivas PW. Group II metabotropic glutamate receptors modulate extracellular glutamate in the nucleus accumbens. The Journal of Pharmacology and Experimental Therapeutics. 300: 162-71. PMID 11752112 DOI: 10.1124/Jpet.300.1.162  0.49
2001 Bonneau R, Tsai J, Ruczinski I, Chivian D, Rohl C, Strauss CE, Baker D. Rosetta in CASP4: progress in ab initio protein structure prediction. Proteins. 119-26. PMID 11835488 DOI: 10.1002/Prot.1170  0.32
2001 Lee MR, Tsai J, Baker D, Kollman PA. Molecular dynamics in the endgame of protein structure prediction. Journal of Molecular Biology. 313: 417-30. PMID 11800566 DOI: 10.1006/Jmbi.2001.5032  0.318
2001 Swanson CJ, Baker DA, Carson D, Worley PF, Kalivas PW. Repeated cocaine administration attenuates group I metabotropic glutamate receptor-mediated glutamate release and behavioral activation: a potential role for Homer. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 9043-52. PMID 11698615 DOI: 10.1523/Jneurosci.21-22-09043.2001  0.702
2001 Baker D, Sali A. Protein Structure Prediction and Structural Genomics Science. 294: 93-96. PMID 11588250 DOI: 10.1126/Science.1065659  0.32
2001 Bonneau R, Tsai J, Ruczinski I, Baker D. Functional inferences from blind ab initio protein structure predictions. Journal of Structural Biology. 134: 186-90. PMID 11551178 DOI: 10.1006/Jsbi.2000.4370  0.314
2001 Nauli S, Kuhlman B, Baker D. Computer-based redesign of a protein folding pathway. Nature Structural Biology. 8: 602-5. PMID 11427890 DOI: 10.1038/89638  0.308
2001 Baker DA, Tran-Nguyen TL, Fuchs RA, Neisewander JL. Influence of individual differences and chronic fluoxetine treatment on cocaine-seeking behavior in rats. Psychopharmacology. 155: 18-26. PMID 11374332 DOI: 10.1007/S002130000676  0.752
2001 O'Neill JW, Kim DE, Baker D, Zhang KY. Structures of the B1 domain of protein L from Peptostreptococcus magnus with a tyrosine to tryptophan substitution. Acta Crystallographica. Section D, Biological Crystallography. 57: 480-7. PMID 11264576 DOI: 10.1107/S0907444901000373  0.311
2001 Simons KT, Strauss C, Baker D. Prospects for ab initio protein structural genomics. Journal of Molecular Biology. 306: 1191-9. PMID 11237627 DOI: 10.1006/Jmbi.2000.4459  0.339
2001 Grantcharova V, Alm EJ, Baker D, Horwich AL. Mechanisms of protein folding. Current Opinion in Structural Biology. 11: 70-82. PMID 11179895 DOI: 10.1016/S0959-440X(00)00176-7  0.313
2000 Bowers PM, Strauss CE, Baker D. De novo protein structure determination using sparse NMR data. Journal of Biomolecular Nmr. 18: 311-8. PMID 11200525 DOI: 10.1023/A:1026744431105  0.33
2000 Plaxco KW, Simons KT, Ruczinski I, Baker D. Topology, stability, sequence, and length: defining the determinants of two-state protein folding kinetics. Biochemistry. 39: 11177-83. PMID 10985762 DOI: 10.1021/Bi000200N  0.328
2000 McCallister EL, Alm E, Baker D. Critical role of β-hairpin formation in protein G folding Nature Structural Biology. 7: 669-673. PMID 10932252 DOI: 10.1038/77971  0.303
2000 Bystroff C, Thorsson V, Baker D. HMMSTR: a hidden Markov model for local sequence-structure correlations in proteins. Journal of Molecular Biology. 301: 173-90. PMID 10926500 DOI: 10.1006/Jmbi.2000.3837  0.318
2000 Baker D. A surprising simplicity to protein folding. Nature. 405: 39-42. PMID 10811210 DOI: 10.1038/35011000  0.327
2000 Plaxco KW, Larson S, Ruczinski I, Riddle DS, Thayer EC, Buchwitz B, Davidson AR, Baker D. Evolutionary conservation in protein folding kinetics. Journal of Molecular Biology. 298: 303-12. PMID 10764599 DOI: 10.1006/Jmbi.1999.3663  0.308
2000 Neisewander JL, Baker DA, Fuchs RA, Tran-Nguyen LT, Palmer A, Marshall JF. Fos protein expression and cocaine-seeking behavior in rats after exposure to a cocaine self-administration environment. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 798-805. PMID 10632609 DOI: 10.1523/Jneurosci.20-02-00798.2000  0.753
1999 Alm E, Baker D. Prediction of protein-folding mechanisms from free-energy landscapes derived from native structures. Proceedings of the National Academy of Sciences of the United States of America. 96: 11305-10. PMID 10500172 DOI: 10.1073/Pnas.96.20.11305  0.311
1999 Tran-Nguyen LT, Baker DA, Grote KA, Solano J, Neisewander JL. Serotonin depletion attenuates cocaine-seeking behavior in rats. Psychopharmacology. 146: 60-6. PMID 10485965 DOI: 10.1007/S002130051088  0.616
1999 Baker DA, Fuchs RA, Tran-Nguyen LT, Palmer AJ, Marshall JF, McPherson RJ, Neisewander JL. Cocaine-seeking behavior and Fos expression in the amygdala produced by cocaine or a cocaine self-administration environment. Annals of the New York Academy of Sciences. 877: 796-9. PMID 10415707 DOI: 10.1111/J.1749-6632.1999.Tb09325.X  0.746
1999 Simons KT, Ruczinski I, Kooperberg C, Fox BA, Bystroff C, Baker D. Improved recognition of native-like protein structures using a combination of sequence-dependent and sequence-independent features of proteins. Proteins. 34: 82-95. PMID 10336385 DOI: 10.1002/(Sici)1097-0134(19990101)34:1<82::Aid-Prot7>3.0.Co;2-A  0.308
1999 Alm E, Baker D. Matching theory and experiment in protein folding. Current Opinion in Structural Biology. 9: 189-96. PMID 10322214 DOI: 10.1016/S0959-440X(99)80027-X  0.324
1999 Simons KT, Bonneau R, Ruczinski I, Baker D. Ab initio protein structure prediction of CASP III targets using ROSETTA Proteins: Structure, Function, and Genetics. 37: 171-176. DOI: 10.1002/(Sici)1097-0134(1999)37:3+<171::Aid-Prot21>3.0.Co;2-Z  0.316
1998 Kim DE, Yi Q, Gladwin ST, Goldberg JM, Baker D. The single helix in protein L is largely disrupted at the rate-limiting step in folding. Journal of Molecular Biology. 284: 807-15. PMID 9826517 DOI: 10.1006/Jmbi.1998.2200  0.305
1998 Khroyan TV, Baker DA, Fuchs RA, Manders N, Neisewander JL. Differential effects of 7-OH-DPAT on amphetamine-induced stereotypy and conditioned place preference. Psychopharmacology. 139: 332-41. PMID 9809854 DOI: 10.1007/S002130050724  0.727
1998 Shortle D, Simons KT, Baker D. Clustering of low-energy conformations near the native structures of small proteins. Proceedings of the National Academy of Sciences of the United States of America. 95: 11158-62. PMID 9736706 DOI: 10.1073/Pnas.95.19.11158  0.319
1998 Baker DA, Fuchs RA, Specio SE, Khroyan TV, Neisewander JL. Effects of intraaccumbens administration of SCH-23390 on cocaine-induced locomotion and conditioned place preference. Synapse (New York, N.Y.). 30: 181-93. PMID 9723788 DOI: 10.1002/(Sici)1098-2396(199810)30:2<181::Aid-Syn8>3.0.Co;2-8  0.753
1998 Baker DA, Specio SE, Tran-Nguyen LT, Neisewander JL. Amphetamine infused into the ventrolateral striatum produces oral stereotypies and conditioned place preference. Pharmacology, Biochemistry, and Behavior. 61: 107-11. PMID 9715812 DOI: 10.1016/S0091-3057(98)00070-7  0.595
1998 Bystroff C, Baker D. Prediction of local structure in proteins using a library of sequence-structure motifs. Journal of Molecular Biology. 281: 565-77. PMID 9698570 DOI: 10.1006/Jmbi.1998.1943  0.301
1998 Tran-Nguyen LT, Fuchs RA, Coffey GP, Baker DA, O'Dell LE, Neisewander JL. Time-dependent changes in cocaine-seeking behavior and extracellular dopamine levels in the amygdala during cocaine withdrawal. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 19: 48-59. PMID 9608576 DOI: 10.1016/S0893-133X(97)00205-4  0.789
1998 Kim DE, Gu H, Baker D. The sequences of small proteins are not extensively optimized for rapid folding by natural selection. Proceedings of the National Academy of Sciences of the United States of America. 95: 4982-6. PMID 9560214 DOI: 10.1073/Pnas.95.9.4982  0.314
1998 Plaxco KW, Riddle DS, Grantcharova V, Baker D. Simplified proteins: minimalist solutions to the 'protein folding problem'. Current Opinion in Structural Biology. 8: 80-5. PMID 9519299 DOI: 10.1016/S0959-440X(98)80013-4  0.321
1997 Khroyan TV, Fuchs RA, Baker DA, Neisewander JL. Effects of D3-preferring agonists 7-OH-PIPAT and PD-128,907 on motor behaviors and place conditioning. Behavioural Pharmacology. 8: 65-74. PMID 9833002 DOI: 10.1097/00008877-199702000-00007  0.71
1997 Riddle DS, Santiago JV, Bray-Hall ST, Doshi N, Grantcharova VP, Yi Q, Baker D. Functional rapidly folding proteins from simplified amino acid sequences. Nature Structural Biology. 4: 805-9. PMID 9334745 DOI: 10.1038/Nsb1097-805  0.313
1997 Simons KT, Kooperberg C, Huang E, Baker D. Assembly of protein tertiary structures from fragments with similar local sequences using simulated annealing and Bayesian scoring functions. Journal of Molecular Biology. 268: 209-25. PMID 9149153 DOI: 10.1006/Jmbi.1997.0959  0.315
1996 Baker DA, Khroyan TV, O'Dell LE, Fuchs RA, Neisewander JL. Differential effects of intra-accumbens sulpiride on cocaine-induced locomotion and conditioned place preference. The Journal of Pharmacology and Experimental Therapeutics. 279: 392-401. PMID 8859018  0.792
1995 Khroyan TV, Baker DA, Neisewander JL. Dose-dependent effects of the D3-preferring agonist 7-OH-DPAT on motor behaviors and place conditioning. Psychopharmacology. 122: 351-7. PMID 8657832 DOI: 10.1007/Bf02246265  0.579
1995 Gu H, Yi Q, Bray ST, Riddle DS, Shiau AK, Baker D. A phage display system for studying the sequence determinants of protein folding. Protein Science : a Publication of the Protein Society. 4: 1108-17. PMID 7549875 DOI: 10.1002/Pro.5560040609  0.301
1994 Baker D, Agard DA. Kinetics versus thermodynamics in protein folding. Biochemistry. 33: 7505-9. PMID 8011615 DOI: 10.1021/Bi00190A002  0.308
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