Alex Sigal, Ph.D. - Publications

Affiliations: 
2005 Weizmann Institute of Science, Rehovot, Israel 
Area:
Cell Biology, General Biophysics

25/90 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Moyano A, Lustig G, Rodel HE, Antal T, Sigal A. Interference with HIV infection of the first cell is essential for viral clearance at sub-optimal levels of drug inhibition. Plos Computational Biology. 16: e1007482. PMID 32017770 DOI: 10.1371/Journal.Pcbi.1007482  0.308
2019 Cromarty R, Sigal A, Liebenberg LJP, McKinnon LR, Abdool Karim SS, Passmore JS, Archary D. Diminished HIV Infection of Target CD4+ T Cells in a Toll-Like Receptor 4 Stimulated Model. Frontiers in Immunology. 10: 1705. PMID 31396221 DOI: 10.3389/Fimmu.2019.01705  0.31
2018 Barichievy S, Naidoo J, Boullé M, Scholefield J, Parihar SP, Coussens AK, Brombacher F, Sigal A, Mhlanga MM. Viral Apoptosis Evasion via the MAPK Pathway by Use of a Host Long Noncoding RNA. Frontiers in Cellular and Infection Microbiology. 8: 263. PMID 30123777 DOI: 10.3389/Fcimb.2018.00263  0.381
2018 Jackson L, Hunter J, Cele S, Ferreira IM, Young AC, Karim F, Madansein R, Dullabh KJ, Chen CY, Buckels NJ, Ganga Y, Khan K, Boulle M, Lustig G, Neher RA, ... Sigal A, et al. Incomplete inhibition of HIV infection results in more HIV infected lymph node cells by reducing cell death. Elife. 7. PMID 29555018 DOI: 10.7554/Elife.30134  0.367
2018 Kim JT, Chang E, Sigal A, Baltimore D. Dendritic cells efficiently transmit HIV to T Cells in a tenofovir and raltegravir insensitive manner. Plos One. 13: e0189945. PMID 29293546 DOI: 10.1371/Journal.Pone.0189945  0.389
2017 Mahamed D, Boulle M, Ganga Y, Mc Arthur C, Skroch S, Oom L, Catinas O, Pillay K, Naicker M, Rampersad S, Mathonsi C, Hunter J, Sreejit G, Pym AS, Lustig G, ... Sigal A, et al. Intracellular growth of Mycobacterium tuberculosis after macrophage cell death leads to serial killing of host cells. Elife. 6. PMID 28130921 DOI: 10.7554/Elife.22028  0.368
2017 Jackson L, Hunter J, Cele S, Ferreira IM, Young AC, Karim F, Madansein R, Dullabh KJ, Chen C, Buckels NJ, Ganga Y, Khan K, Boulle M, Lustig G, Neher RA, ... Sigal A, et al. Author response: Incomplete inhibition of HIV infection results in more HIV infected lymph node cells by reducing cell death Elife. DOI: 10.7554/Elife.30134.040  0.319
2016 Boullé M, Müller TG, Dähling S, Ganga Y, Jackson L, Mahamed D, Oom L, Lustig G, Neher RA, Sigal A. HIV Cell-to-Cell Spread Results in Earlier Onset of Viral Gene Expression by Multiple Infections per Cell. Plos Pathogens. 12: e1005964. PMID 27812216 DOI: 10.1371/Journal.Ppat.1005964  0.46
2014 Farkash-Amar S, Zimmer A, Eden E, Cohen A, Geva-Zatorsky N, Cohen L, Milo R, Sigal A, Danon T, Alon U. Noise genetics: inferring protein function by correlating phenotype with protein levels and localization in individual human cells. Plos Genetics. 10: e1004176. PMID 24603725 DOI: 10.1371/Journal.Pgen.1004176  0.644
2012 Farkash-Amar S, Eden E, Cohen A, Geva-Zatorsky N, Cohen L, Milo R, Sigal A, Danon T, Alon U. Dynamic proteomics of human protein level and localization across the cell cycle. Plos One. 7: e48722. PMID 23144944 DOI: 10.1371/Journal.Pone.0048722  0.701
2012 Sigal A, Baltimore D. As good as it gets? The problem of HIV persistence despite antiretroviral drugs. Cell Host & Microbe. 12: 132-8. PMID 22901535 DOI: 10.1016/J.Chom.2012.07.005  0.324
2012 Puliafito A, Hufnagel L, Neveu P, Streichan S, Sigal A, Fygenson DK, Shraiman BI. Collective and single cell behavior in epithelial contact inhibition. Proceedings of the National Academy of Sciences of the United States of America. 109: 739-44. PMID 22228306 DOI: 10.1073/Pnas.1007809109  0.496
2011 Sigal A, Kim JT, Balazs AB, Dekel E, Mayo A, Milo R, Baltimore D. Cell-to-cell spread of HIV permits ongoing replication despite antiretroviral therapy. Nature. 477: 95-8. PMID 21849975 DOI: 10.1038/Nature10347  0.404
2010 Frenkel-Morgenstern M, Cohen AA, Geva-Zatorsky N, Eden E, Prilusky J, Issaeva I, Sigal A, Cohen-Saidon C, Liron Y, Cohen L, Danon T, Perzov N, Alon U. Dynamic Proteomics: a database for dynamics and localizations of endogenous fluorescently-tagged proteins in living human cells. Nucleic Acids Research. 38: D508-12. PMID 19820112 DOI: 10.1093/Nar/Gkp808  0.649
2009 Cohen-Saidon C, Cohen AA, Sigal A, Liron Y, Alon U. Dynamics and variability of ERK2 response to EGF in individual living cells. Molecular Cell. 36: 885-93. PMID 20005850 DOI: 10.1016/J.Molcel.2009.11.025  0.665
2009 Cohen AA, Kalisky T, Mayo A, Geva-Zatorsky N, Danon T, Issaeva I, Kopito RB, Perzov N, Milo R, Sigal A, Alon U. Protein dynamics in individual human cells: experiment and theory. Plos One. 4: e4901. PMID 19381343 DOI: 10.1371/Journal.Pone.0004901  0.702
2008 Cohen AA, Geva-Zatorsky N, Eden E, Frenkel-Morgenstern M, Issaeva I, Sigal A, Milo R, Cohen-Saidon C, Liron Y, Kam Z, Cohen L, Danon T, Perzov N, Alon U. Dynamic proteomics of individual cancer cells in response to a drug. Science (New York, N.Y.). 322: 1511-6. PMID 19023046 DOI: 10.1126/Science.1160165  0.66
2007 Sigal A, Danon T, Cohen A, Milo R, Geva-Zatorsky N, Lustig G, Liron Y, Alon U, Perzov N. Generation of a fluorescently labeled endogenous protein library in living human cells. Nature Protocols. 2: 1515-27. PMID 17571059 DOI: 10.1038/Nprot.2007.197  0.647
2006 Sigal A, Milo R, Cohen A, Geva-Zatorsky N, Klein Y, Liron Y, Rosenfeld N, Danon T, Perzov N, Alon U. Variability and memory of protein levels in human cells. Nature. 444: 643-6. PMID 17122776 DOI: 10.1038/Nature05316  0.736
2006 Sigal A, Milo R, Cohen A, Geva-Zatorsky N, Klein Y, Alaluf I, Swerdlin N, Perzov N, Danon T, Liron Y, Raveh T, Carpenter AE, Lahav G, Alon U. Dynamic proteomics in individual human cells uncovers widespread cell-cycle dependence of nuclear proteins. Nature Methods. 3: 525-31. PMID 16791210 DOI: 10.1038/Nmeth892  0.754
2006 Geva-Zatorsky N, Rosenfeld N, Itzkovitz S, Milo R, Sigal A, Dekel E, Yarnitzky T, Liron Y, Polak P, Lahav G, Alon U. Oscillations and variability in the p53 system. Molecular Systems Biology. 2: 2006.0033. PMID 16773083 DOI: 10.1038/Msb4100068  0.732
2004 Lahav G, Rosenfeld N, Sigal A, Geva-Zatorsky N, Levine AJ, Elowitz MB, Alon U. Dynamics of the p53-Mdm2 feedback loop in individual cells. Nature Genetics. 36: 147-50. PMID 14730303 DOI: 10.1038/Ng1293  0.71
2001 Sigal A, Matas D, Almog N, Goldfinger N, Rotter V. The C-terminus of mutant p53 is necessary for its ability to interfere with growth arrest or apoptosis. Oncogene. 20: 4891-8. PMID 11521201 DOI: 10.1038/Sj.Onc.1204724  0.339
2001 Seluanov A, Gorbunova V, Falcovitz A, Sigal A, Milyavsky M, Zurer I, Shohat G, Goldfinger N, Rotter V. Change of the death pathway in senescent human fibroblasts in response to DNA damage is caused by an inability to stabilize p53. Molecular and Cellular Biology. 21: 1552-64. PMID 11238892 DOI: 10.1128/Mcb.21.5.1552-1564.2001  0.38
2000 Sigal A, Bleijs DA, Grabovsky V, van Vliet SJ, Dwir O, Figdor CG, van Kooyk Y, Alon R. The LFA-1 integrin supports rolling adhesions on ICAM-1 under physiological shear flow in a permissive cellular environment. Journal of Immunology (Baltimore, Md. : 1950). 165: 442-52. PMID 10861083 DOI: 10.4049/Jimmunol.165.1.442  0.305
Low-probability matches (unlikely to be authored by this person)
2001 Matas D, Sigal A, Stambolsky P, Milyavsky M, Weisz L, Schwartz D, Goldfinger N, Rotter V. Integrity of the N-terminal transcription domain of p53 is required for mutant p53 interference with drug-induced apoptosis. The Embo Journal. 20: 4163-72. PMID 11483519 DOI: 10.1093/Emboj/20.15.4163  0.288
2007 Lavelle C, Sigal A. Systems biology meets chromatin function: a report on the Fourth Elmau Conference on Nuclear Organization. Chromosome Research : An International Journal On the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology. 15: 247-56. PMID 17279452 DOI: 10.1007/S10577-006-1118-6  0.285
2022 Meng B, Abdullahi A, Ferreira IATM, Goonawardane N, Saito A, Kimura I, Yamasoba D, Gerber PP, Fatihi S, Rathore S, Zepeda SK, Papa G, Kemp SA, Ikeda T, Toyoda M, ... ... Sigal A, et al. Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts tropism and fusogenicity. Nature. PMID 35104837 DOI: 10.1038/s41586-022-04474-x  0.278
2017 Mahamed D, Boulle M, Ganga Y, Mc Arthur C, Skroch S, Oom L, Catinas O, Pillay K, Naicker M, Rampersad S, Mathonsi C, Hunter J, Wong EB, Suleman M, Sreejit G, ... ... Sigal A, et al. Correction: Intracellular growth of Mycobacterium tuberculosis after macrophage cell death leads to serial killing of host cells. Elife. 6. PMID 28475039 DOI: 10.7554/eLife.28205  0.272
2022 Nkosi T, Chasara C, Papadopoulos AO, Nguni TL, Karim F, Moosa MS, Gazy I, Jambo K, Hanekom W, Sigal A, Ndhlovu ZM. Unsuppressed HIV infection impairs T cell responses to SARS-CoV-2 infection and abrogates T cell cross-recognition. Elife. 11. PMID 35880744 DOI: 10.7554/eLife.78374  0.252
2014 Costiniuk CT, Sigal A, Jenabian MA, Nijs P, Wilson D. Short communication: Lower baseline CD4 count is associated with a greater propensity toward virological failure in a cohort of South African HIV patients. Aids Research and Human Retroviruses. 30: 531-4. PMID 24803320 DOI: 10.1089/Aid.2014.0011  0.248
2022 Lustig G, Ganga Y, Rodel H, Tegally H, Jackson L, Cele S, Khan K, Jule Z, Reedoy K, Karim F, Bernstein M, Moosa MS, Archary D, de Oliveira T, Lessells R, ... ... Sigal A, et al. SARS-CoV-2 evolves increased infection elicited cell death and fusion in an immunosuppressed individual. Medrxiv : the Preprint Server For Health Sciences. PMID 36451879 DOI: 10.1101/2022.11.23.22282673  0.239
2022 Keeton R, Tincho MB, Ngomti A, Baguma R, Benede N, Suzuki A, Khan K, Cele S, Bernstein M, Karim F, Madzorera SV, Moyo-Gwete T, Mennen M, Skelem S, Adriaanse M, ... ... Sigal A, et al. T cell responses to SARS-CoV-2 spike cross-recognize Omicron. Nature. PMID 35102311 DOI: 10.1038/s41586-022-04460-3  0.233
2022 Reuschl AK, Mesner D, Shivkumar M, Whelan MVX, Pallett LJ, Guerra-Assunção JA, Madansein R, Dullabh KJ, Sigal A, Thornhill JP, Herrera C, Fidler S, Noursadeghi M, Maini MK, Jolly C. HIV-1 Vpr drives a tissue residency-like phenotype during selective infection of resting memory T cells. Cell Reports. 39: 110650. PMID 35417711 DOI: 10.1016/j.celrep.2022.110650  0.232
2020 Naicker N, Sigal A, Naidoo K. Metformin as Host-Directed Therapy for TB Treatment: Scoping Review. Frontiers in Microbiology. 11: 435. PMID 32411100 DOI: 10.3389/Fmicb.2020.00435  0.215
2024 Ng'uni TL, Musale V, Nkosi T, Mandolo J, Mvula M, Michelo C, Karim F, Moosa MYS, Khan K, Jambo KC, Hanekom W, Sigal A, Kilembe W, Ndhlovu ZM. Low pre-existing endemic human coronavirus (HCoV-NL63)-specific T cell frequencies are associated with impaired SARS-CoV-2-specific T cell responses in people living with HIV. Frontiers in Immunology. 14: 1291048. PMID 38343437 DOI: 10.3389/fimmu.2023.1291048  0.21
2023 Krause RGE, Moyo-Gwete T, Richardson SI, Makhado Z, Manamela NP, Hermanus T, Mkhize NN, Keeton R, Benede N, Mennen M, Skelem S, Karim F, Khan K, Riou C, Ntusi NAB, ... ... Sigal A, et al. Infection pre-Ad26.COV2.S-vaccination primes greater class switching and reduced CXCR5 expression by SARS-CoV-2-specific memory B cells. Npj Vaccines. 8: 119. PMID 37573434 DOI: 10.1038/s41541-023-00724-9  0.204
2021 Rodel HE, Ferreira IATM, Ziegler CGK, Ganga Y, Bernstein M, Hwa SH, Nargan K, Lustig G, Kaplan G, Noursadeghi M, Shalek AK, Steyn AJC, Sigal A. Aggregated Enhances the Inflammatory Response. Frontiers in Microbiology. 12: 757134. PMID 34925266 DOI: 10.3389/fmicb.2021.757134  0.202
2022 Krause R, Snyman J, Shi-Hsia H, Muema D, Karim F, Ganga Y, Ngoepe A, Zungu Y, Gazy I, Bernstein M, Khan K, Mazibuko M, Mthabela N, Ramjit D, Limbo O, ... ... Sigal A, et al. HIV skews the SARS-CoV-2 B cell response toward an extrafollicular maturation pathway. Elife. 11. PMID 36300787 DOI: 10.7554/eLife.79924  0.198
2021 Lustig G, Cele S, Karim F, Derache A, Ngoepe A, Khan K, Gosnell BI, Moosa MS, Ntshuba N, Marais S, Jeena PM, Govender K, Adamson J, Kløverpris H, Gupta RK, ... ... Sigal A, et al. T cell derived HIV-1 is present in the CSF in the face of suppressive antiretroviral therapy. Plos Pathogens. 17: e1009871. PMID 34555123 DOI: 10.1371/journal.ppat.1009871  0.192
2023 Khan K, Lustig G, Römer C, Reedoy K, Jule Z, Karim F, Ganga Y, Bernstein M, Baig Z, Jackson L, Mahlangu B, Mnguni A, Nzimande A, Stock N, Kekana D, ... ... Sigal A, et al. Evolution and neutralization escape of the SARS-CoV-2 BA.2.86 subvariant. Nature Communications. 14: 8078. PMID 38057313 DOI: 10.1038/s41467-023-43703-3  0.192
2023 Lustig G, Ganga Y, Rodel HE, Tegally H, Khairallah A, Jackson L, Cele S, Khan K, Jule Z, Reedoy K, Karim F, Bernstein M, Ndung'u T, Moosa MS, Archary D, ... ... Sigal A, et al. SARS-CoV-2 infection in immunosuppression evolves sub-lineages which independently accumulate neutralization escape mutations. Virus Evolution. 10: vead075. PMID 38361824 DOI: 10.1093/ve/vead075  0.187
2022 Keeton R, Tincho MB, Ngomti A, Baguma R, Benede N, Suzuki A, Khan K, Cele S, Bernstein M, Karim F, Madzorera SV, Moyo-Gwete T, Mennen M, Skelem S, Adriaanse M, ... ... Sigal A, et al. Author Correction: T cell responses to SARS-CoV-2 spike cross-recognize Omicron. Nature. PMID 35396582 DOI: 10.1038/s41586-022-04708-y  0.185
2024 Karim F, Riou C, Bernstein M, Jule Z, Lustig G, van Graan S, Keeton RS, Upton JL, Ganga Y, Khan K, Reedoy K, Mazibuko M, Govender K, Thambu K, Ngcobo N, ... ... Sigal A, et al. Clearance of persistent SARS-CoV-2 associates with increased neutralizing antibodies in advanced HIV disease post-ART initiation. Nature Communications. 15: 2360. PMID 38491050 DOI: 10.1038/s41467-024-46673-2  0.173
2023 Hysenaj L, Little S, Kulhanek K, Magnen M, Bahl K, Gbenedio OM, Prinz M, Rodriguez L, Andersen C, Rao AA, Shen A, Lone JC, Lupin-Jimenez LC, Bonser LR, Serwas NK, ... ... Sigal A, et al. SARS-CoV-2 infection of airway organoids reveals conserved use of Tetraspanin-8 by Ancestral, Delta, and Omicron variants. Stem Cell Reports. PMID 36827975 DOI: 10.1016/j.stemcr.2023.01.011  0.161
2023 Naicker N, Rodel H, Perumal R, Ganga Y, Bernstein M, Benede N, Abdool Karim S, Padayacthi N, Sigal A, Naidoo K. Metformin Increases Cell Viability and Regulates Pro-Inflammatory Response to Mtb. Infection and Drug Resistance. 16: 3629-3638. PMID 37309381 DOI: 10.2147/IDR.S401403  0.145
2021 Snyman J, Hwa SH, Krause R, Muema D, Reddy T, Ganga Y, Karim F, Leslie A, Sigal A, Ndung'u T. Similar antibody responses against SARS-CoV-2 in HIV uninfected and infected individuals on antiretroviral therapy during the first South African infection wave. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 34472583 DOI: 10.1093/cid/ciab758  0.14
2021 Karim F, Gazy I, Cele S, Zungu Y, Krause R, Bernstein M, Khan K, Ganga Y, Rodel HE, Mthabela N, Mazibuko M, Muema D, Ramjit D, Ndung'u T, Hanekom W, ... ... Sigal A, et al. HIV status alters disease severity and immune cell responses in beta variant SARS-CoV-2 infection wave. Elife. 10. PMID 34608862 DOI: 10.7554/eLife.67397  0.139
2023 Mühlemann B, Wilks SH, Baracco L, Bekliz M, Carreño JM, Corman VM, Davis-Gardner ME, Dejnirattisai W, Diamond MS, Douek DC, Drosten C, Eckerle I, Edara VV, Ellis M, Fouchier RAM, ... ... Sigal A, et al. Comparative Analysis of SARS-CoV-2 Antigenicity across Assays and in Human and Animal Model Sera. Biorxiv : the Preprint Server For Biology. PMID 37808679 DOI: 10.1101/2023.09.27.559689  0.125
2021 Kolloli A, Kumar R, Singh P, Narang A, Kaplan G, Sigal A, Subbian S. Aggregation state of Mycobacterium tuberculosis impacts host immunity and augments pulmonary disease pathology. Communications Biology. 4: 1256. PMID 34732811 DOI: 10.1038/s42003-021-02769-9  0.12
2021 Cele S, Jackson L, Khan K, Khoury DS, Moyo-Gwete T, Tegally H, Scheepers C, Amoako D, Karim F, Bernstein M, Lustig G, Archary D, Smith M, Ganga Y, Jule Z, ... ... Sigal A, et al. SARS-CoV-2 Omicron has extensive but incomplete escape of Pfizer BNT162b2 elicited neutralization and requires ACE2 for infection. Medrxiv : the Preprint Server For Health Sciences. PMID 34909788 DOI: 10.1101/2021.12.08.21267417  0.106
2021 Khan K, Lustig G, Bernstein M, Archary D, Cele S, Karim F, Smith M, Ganga Y, Jule Z, Reedoy K, Miya Y, Mthabela N, Magula NP, Lessells R, de Oliveira T, ... ... Sigal A, et al. Immunogenicity of SARS-CoV-2 infection and Ad26.CoV2.S vaccination in people living with HIV. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 34893824 DOI: 10.1093/cid/ciab1008  0.103
2021 Skelly DT, Harding AC, Gilbert-Jaramillo J, Knight ML, Longet S, Brown A, Adele S, Adland E, Brown H, Tipton T, Stafford L, Mentzer AJ, Johnson SA, Amini A, ... ... Sigal A, et al. Two doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern. Nature Communications. 12: 5061. PMID 34404775 DOI: 10.1038/s41467-021-25167-5  0.101
2021 Tegally H, Wilkinson E, Lessells RJ, Giandhari J, Pillay S, Msomi N, Mlisana K, Bhiman JN, von Gottberg A, Walaza S, Fonseca V, Allam M, Ismail A, Glass AJ, Engelbrecht S, ... ... Sigal A, et al. Sixteen novel lineages of SARS-CoV-2 in South Africa. Nature Medicine. PMID 33531709 DOI: 10.1038/s41591-021-01255-3  0.1
2021 Tegally H, Wilkinson E, Giovanetti M, Iranzadeh A, Fonseca V, Giandhari J, Doolabh D, Pillay S, San EJ, Msomi N, Mlisana K, von Gottberg A, Walaza S, Allam M, Ismail A, ... ... Sigal A, et al. Emergence of a SARS-CoV-2 variant of concern with mutations in spike glycoprotein. Nature. PMID 33690265 DOI: 10.1038/s41586-021-03402-9  0.099
2021 Khan K, Karim F, Cele S, San JE, Lustig G, Tegally H, Bernstein M, Ganga Y, Jule Z, Reedoy K, Ngcobo N, Mazibuko M, Mthabela N, Mhlane Z, Mbatha N, ... ... Sigal A, et al. Omicron infection enhances neutralizing immunity against the Delta variant. Medrxiv : the Preprint Server For Health Sciences. PMID 34981076 DOI: 10.1101/2021.12.27.21268439  0.097
2022 Cele S, Karim F, Lustig G, San JE, Hermanus T, Tegally H, Snyman J, Moyo-Gwete T, Wilkinson E, Bernstein M, Khan K, Hwa SH, Tilles SW, Singh L, Giandhari J, ... ... Sigal A, et al. SARS-CoV-2 prolonged infection during advanced HIV disease evolves extensive immune escape. Cell Host & Microbe. 30: 154-162.e5. PMID 35120605 DOI: 10.1016/j.chom.2022.01.005  0.094
2022 Khan K, Karim F, Cele S, Reedoy K, San JE, Lustig G, Tegally H, Rosenberg Y, Bernstein M, Jule Z, Ganga Y, Ngcobo N, Mazibuko M, Mthabela N, Mhlane Z, ... ... Sigal A, et al. Omicron infection enhances Delta antibody immunity in vaccinated persons. Nature. PMID 35523247 DOI: 10.1038/s41586-022-04830-x  0.089
2022 Khan K, Karim F, Ganga Y, Bernstein M, Jule Z, Reedoy K, Cele S, Lustig G, Amoako D, Wolter N, Samsunder N, Sivro A, San JE, Giandhari J, Tegally H, ... ... Sigal A, et al. Omicron BA.4/BA.5 escape neutralizing immunity elicited by BA.1 infection. Nature Communications. 13: 4686. PMID 35948557 DOI: 10.1038/s41467-022-32396-9  0.088
2022 Scheepers C, Everatt J, Amoako DG, Tegally H, Wibmer CK, Mnguni A, Ismail A, Mahlangu B, Lambson BE, Martin DP, Wilkinson E, San JE, Giandhari J, Manamela N, Ntuli N, ... ... Sigal A, et al. Emergence and phenotypic characterization of the global SARS-CoV-2 C.1.2 lineage. Nature Communications. 13: 1976. PMID 35396511 DOI: 10.1038/s41467-022-29579-9  0.087
2023 Allué-Guardia A, Torrelles JB, Sigal A. Tuberculosis and COVID-19 in the elderly: factors driving a higher burden of disease. Frontiers in Immunology. 14: 1250198. PMID 37841265 DOI: 10.3389/fimmu.2023.1250198  0.082
2023 Hao L, Hsiang TY, Dalmat RR, Ireton R, Morton JF, Stokes C, Netland J, Hale M, Thouvenel C, Wald A, Franko NM, Huden K, Chu HY, Sigal A, Greninger AL, et al. Dynamics of SARS-CoV-2 VOC Neutralization and Novel mAb Reveal Protection against Omicron. Viruses. 15. PMID 36851745 DOI: 10.3390/v15020530  0.077
2021 Cele S, Karim F, Lustig G, San JE, Hermanus T, Tegally H, Snyman J, Moyo-Gwete T, Wilkinson E, Bernstein M, Khan K, Hwa SH, Tilles SW, Singh L, Giandhari J, ... ... Sigal A, et al. SARS-CoV-2 evolved during advanced HIV disease immunosuppression has Beta-like escape of vaccine and Delta infection elicited immunity. Medrxiv : the Preprint Server For Health Sciences. PMID 34909798 DOI: 10.1101/2021.09.14.21263564  0.071
2008 Schroeder A, Sigal A, Turjeman K, Barenholz Y. Using PEGylated nano-liposomes to target tissue invaded by a foreign body. Journal of Drug Targeting. 16: 591-5. PMID 18686129 DOI: 10.1080/10611860802228939  0.07
2022 Hwa SH, Snyman J, Bernstein M, Ganga Y, Cele S, Muema D, Tan CW, Khan K, Karim F, Hanekom W, Bernstein L, Kaufmann SHE, Wang LF, Ndung'u T, Sigal A. HIV viremia is associated with compromised SARS-CoV-2 Beta variant neutralization. The Journal of Infectious Diseases. PMID 35975942 DOI: 10.1093/infdis/jiac343  0.069
2022 Martin DP, Lytras S, Lucaci AG, Maier W, Grüning B, Shank SD, Weaver S, MacLean OA, Orton RJ, Lemey P, Boni MF, Tegally H, Harkins G, Scheepers C, Bhiman JN, ... ... Sigal A, et al. Selection analysis identifies unusual clustered mutational changes in Omicron lineage BA.1 that likely impact Spike function. Biorxiv : the Preprint Server For Biology. PMID 35075456 DOI: 10.1101/2022.01.14.476382  0.069
2022 Tan CW, Chia WN, Zhu F, Young BE, Chantasrisawad N, Hwa SH, Yeoh AY, Lim BL, Yap WC, Pada SKMS, Tan SY, Jantarabenjakul W, Toh LK, Chen S, Zhang J, ... ... Sigal A, et al. SARS-CoV-2 Omicron variant emerged under immune selection. Nature Microbiology. PMID 36195753 DOI: 10.1038/s41564-022-01246-1  0.068
2011 Avnir Y, Turjeman K, Tulchinsky D, Sigal A, Kizelsztein P, Tzemach D, Gabizon A, Barenholz Y. Fabrication principles and their contribution to the superior in vivo therapeutic efficacy of nano-liposomes remote loaded with glucocorticoids. Plos One. 6: e25721. PMID 21998684 DOI: 10.1371/journal.pone.0025721  0.068
2022 Martin DP, Lytras S, Lucaci AG, Maier W, Grüning B, Shank SD, Weaver S, MacLean OA, Orton RJ, Lemey P, Boni MF, Tegally H, Harkins GW, Scheepers C, Bhiman JN, ... ... Sigal A, et al. Selection analysis identifies clusters of unusual mutational changes in Omicron lineage BA.1 that likely impact Spike function. Molecular Biology and Evolution. PMID 35325204 DOI: 10.1093/molbev/msac061  0.067
2021 Cele S, Jackson L, Khoury DS, Khan K, Moyo-Gwete T, Tegally H, San JE, Cromer D, Scheepers C, Amoako DG, Karim F, Bernstein M, Lustig G, Archary D, Smith M, ... ... Sigal A, et al. Omicron extensively but incompletely escapes Pfizer BNT162b2 neutralization. Nature. PMID 35016196 DOI: 10.1038/s41586-021-04387-1  0.066
2024 Tomasicchio M, Jaumdally S, Wilson L, Kotze A, Semple L, Meier S, Pooran A, Esmail A, Pillay K, Roberts R, Kriel R, Meldau R, Oelofse S, Mandviwala C, Burns J, ... ... Sigal A, et al. SARS-CoV-2 Viral Replication Persists in the Human Lung for Several Weeks after Symptom Onset. American Journal of Respiratory and Critical Care Medicine. PMID 38226855 DOI: 10.1164/rccm.202308-1438OC  0.063
2021 Garcia-Beltran WF, Lam EC, Denis KS, Nitido AD, Garcia ZH, Hauser BM, Feldman J, Pavlovic MN, Gregory DJ, Poznansky MC, Sigal A, Schmidt AG, Iafrate AJ, Naranbhai V, Balazs AB. Circulating SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity. Medrxiv : the Preprint Server For Health Sciences. PMID 33619506 DOI: 10.1101/2021.02.14.21251704  0.063
2021 Garcia-Beltran WF, Lam EC, St Denis K, Nitido AD, Garcia ZH, Hauser BM, Feldman J, Pavlovic MN, Gregory DJ, Poznansky MC, Sigal A, Schmidt AG, Iafrate AJ, Naranbhai V, Balazs AB. Multiple SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity. Cell. PMID 33743213 DOI: 10.1016/j.cell.2021.03.013  0.053
2012 Ulmansky R, Turjeman K, Baru M, Katzavian G, Harel M, Sigal A, Naparstek Y, Barenholz Y. Glucocorticoids in nano-liposomes administered intravenously and subcutaneously to adjuvant arthritis rats are superior to the free drugs in suppressing arthritis and inflammatory cytokines. Journal of Controlled Release : Official Journal of the Controlled Release Society. 160: 299-305. PMID 22226777 DOI: 10.1016/j.jconrel.2011.12.024  0.051
2022 Khan K, Karim F, Ganga Y, Bernstein M, Jule Z, Reedoy K, Cele S, Lustig G, Amoako D, Wolter N, Samsunder N, Sivro A, San JE, Giandhari J, Tegally H, ... ... Sigal A, et al. Author Correction: Omicron BA.4/BA.5 escape neutralizing immunity elicited by BA.1 infection. Nature Communications. 13: 6057. PMID 36229444 DOI: 10.1038/s41467-022-33371-0  0.049
2022 Sigal A, Milo R, Jassat W. Estimating disease severity of Omicron and Delta SARS-CoV-2 infections. Nature Reviews. Immunology. PMID 35414124 DOI: 10.1038/s41577-022-00720-5  0.048
2022 Greaney AJ, Starr TN, Eguia RT, Loes AN, Khan K, Karim F, Cele S, Bowen JE, Logue JK, Corti D, Veesler D, Chu HY, Sigal A, Bloom JD. A SARS-CoV-2 variant elicits an antibody response with a shifted immunodominance hierarchy. Plos Pathogens. 18: e1010248. PMID 35134084 DOI: 10.1371/journal.ppat.1010248  0.048
2021 Greaney AJ, Starr TN, Eguia RT, Loes AN, Khan K, Karim F, Cele S, Bowen JE, Logue JK, Corti D, Veesler D, Chu HY, Sigal A, Bloom JD. A SARS-CoV-2 variant elicits an antibody response with a shifted immunodominance hierarchy. Biorxiv : the Preprint Server For Biology. PMID 34671768 DOI: 10.1101/2021.10.12.464114  0.048
2021 Faulkner N, Ng KW, Wu MY, Harvey R, Margaritis M, Paraskevopoulou S, Houlihan C, Hussain S, Greco M, Bolland W, Warchal S, Heaney J, Rickman H, Spyer M, Frampton D, ... ... Sigal A, et al. Reduced antibody cross-reactivity following infection with B.1.1.7 than with parental SARS-CoV-2 strains. Elife. 10. PMID 34323691 DOI: 10.7554/eLife.69317  0.042
2023 Riou C, Bhiman JN, Ganga Y, Sawry S, Ayres F, Baguma R, Balla SR, Benede N, Bernstein M, Besethi AS, Cele S, Crowther C, Dhar M, Geyer S, Gill K, ... ... Sigal A, et al. Safety and immunogenicity of booster vaccination and fractional dosing with Ad26.COV2.S or BNT162b2 in Ad26.COV2.S-vaccinated participants. Medrxiv : the Preprint Server For Health Sciences. PMID 38045321 DOI: 10.1101/2023.11.20.23298785  0.04
2021 Cele S, Gazy I, Jackson L, Hwa SH, Tegally H, Lustig G, Giandhari J, Pillay S, Wilkinson E, Naidoo Y, Karim F, Ganga Y, Khan K, Bernstein M, Balazs AB, ... ... Sigal A, et al. Escape of SARS-CoV-2 501Y.V2 from neutralization by convalescent plasma. Nature. PMID 33780970 DOI: 10.1038/s41586-021-03471-w  0.039
2022 Greaney AJ, Eguia RT, Starr TN, Khan K, Franko N, Logue JK, Lord SM, Speake C, Chu HY, Sigal A, Bloom JD. The SARS-CoV-2 Delta variant induces an antibody response largely focused on class 1 and 2 antibody epitopes. Plos Pathogens. 18: e1010592. PMID 35767821 DOI: 10.1371/journal.ppat.1010592  0.038
2022 Greaney AJ, Eguia RT, Starr TN, Khan K, Franko N, Logue JK, Lord SM, Speake C, Chu HY, Sigal A, Bloom JD. The SARS-CoV-2 Delta variant induces an antibody response largely focused on class 1 and 2 antibody epitopes. Biorxiv : the Preprint Server For Biology. PMID 35313588 DOI: 10.1101/2022.03.12.484088  0.038
2023 Kaufmann SHE, Sigal A, Sawitzki B, Sher A. Editorial: The Covid-19 and TB syndemic: differences and similarities. Frontiers in Immunology. 14: 1340231. PMID 38094299 DOI: 10.3389/fimmu.2023.1340231  0.036
2022 Wells G, Glasgow JN, Nargan K, Lumamba K, Madansein R, Maharaj K, Perumal LY, Matthew M, Hunter RL, Pacl H, Peabody Lever JE, Stanford DD, Singh SP, Bajpai P, Manne U, ... ... Sigal A, et al. A high-resolution 3D atlas of the spectrum of tuberculous and COVID-19 lung lesions. Embo Molecular Medicine. e16283. PMID 36285507 DOI: 10.15252/emmm.202216283  0.035
2009 Kizelsztein P, Ovadia H, Garbuzenko O, Sigal A, Barenholz Y. Pegylated nanoliposomes remote-loaded with the antioxidant tempamine ameliorate experimental autoimmune encephalomyelitis. Journal of Neuroimmunology. 213: 20-5. PMID 19564052 DOI: 10.1016/J.Jneuroim.2009.05.019  0.035
2021 Garcia-Beltran WF, Lam EC, St Denis K, Nitido AD, Garcia ZH, Hauser BM, Feldman J, Pavlovic MN, Gregory DJ, Poznansky MC, Sigal A, Schmidt AG, Iafrate AJ, Naranbhai V, Balazs AB. Multiple SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity. Cell. 184: 2523. PMID 33930298 DOI: 10.1016/j.cell.2021.04.006  0.028
2023 Sigal A. Boosting in the age of Omicron. Elife. 12. PMID 37066867 DOI: 10.7554/eLife.87358  0.024
2022 Sigal A. Milder disease with Omicron: is it the virus or the pre-existing immunity? Nature Reviews. Immunology. 22: 69-71. PMID 35046570 DOI: 10.1038/s41577-022-00678-4  0.024
2021 Madhi SA, Baillie V, Cutland CL, Voysey M, Koen AL, Fairlie L, Padayachee SD, Dheda K, Barnabas SL, Bhorat QE, Briner C, Kwatra G, Ahmed K, Aley P, Bhikha S, ... ... Sigal A, et al. Efficacy of the ChAdOx1 nCoV-19 Covid-19 Vaccine against the B.1.351 Variant. The New England Journal of Medicine. PMID 33725432 DOI: 10.1056/NEJMoa2102214  0.023
Hide low-probability matches.