| Year |
Citation |
Score |
| 2022 |
Peiris MN, Meyer AN, Warda D, Campos AR, Donoghue DJ. Proteomic analysis reveals dual requirement for Grb2 and PLCγ1 interactions for BCR-FGFR1-Driven 8p11 cell proliferation. Oncotarget. 13: 659-676. PMID 35574218 DOI: 10.18632/oncotarget.28228 |
0.301 |
|
| 2020 |
Li F, Meyer AN, Peiris MN, Nelson KN, Donoghue DJ. Oncogenic fusion protein FGFR2-PPHLN1: Requirements for biological activation, and efficacy of inhibitors. Translational Oncology. 13: 100853. PMID 32854034 DOI: 10.1016/J.Tranon.2020.100853 |
0.353 |
|
| 2020 |
Peiris MN, Li F, Meyer AN, Warda D, Donoghue DJ. Abstract 5933: Biochemical characterization of FGFR2-PPHLN1 and BCR-FGFR1, drivers of epithelial and hematological malignancies Cancer Research. 80: 5933-5933. DOI: 10.1158/1538-7445.Am2020-5933 |
0.46 |
|
| 2019 |
Li F, Peiris MN, Donoghue DJ. Functions of FGFR2 corrupted by translocations in intrahepatic cholangiocarcinoma. Cytokine & Growth Factor Reviews. PMID 31899106 DOI: 10.1016/J.Cytogfr.2019.12.005 |
0.351 |
|
| 2019 |
Peiris MN, Meyer AN, Nelson KN, Bisom-Rapp EW, Donoghue DJ. Oncogenic fusion protein BCR-FGFR1 requires BCR-mediated oligomerization and chaperonin Hsp90 for activation. Haematologica. PMID 31439673 DOI: 10.3324/Haematol.2019.220871 |
0.405 |
|
| 2019 |
Peiris MN, Li F, Donoghue DJ. BCR: a promiscuous fusion partner in hematopoietic disorders. Oncotarget. 10: 2738-2754. PMID 31105873 DOI: 10.18632/Oncotarget.26837 |
0.37 |
|
| 2018 |
Nelson KN, Meyer AN, Wang CG, Donoghue DJ. Oncogenic driver FGFR3-TACC3 is dependent on membrane trafficking and ERK signaling. Oncotarget. 9: 34306-34319. PMID 30344944 DOI: 10.18632/Oncotarget.26142 |
0.396 |
|
| 2018 |
Meyer AN, Gallo LH, Ko J, Cardenas G, Nelson KN, Siari A, Campos AR, Whisenant TC, Donoghue DJ. Oncogenic mutations in IKKβ function through global changes induced by K63-linked ubiquitination and result in autocrine stimulation. Plos One. 13: e0206014. PMID 30335863 DOI: 10.1371/Journal.Pone.0206014 |
0.387 |
|
| 2017 |
Upadhyay A, Arsi K, Wagle BR, Upadhyaya I, Shrestha S, Donoghue AM, Donoghue DJ. Trans-Cinnamaldehyde, Carvacrol, and Eugenol Reduce Campylobacter jejuni Colonization Factors and Expression of Virulence Genes in Vitro. Frontiers in Microbiology. 8: 713. PMID 28487683 DOI: 10.3389/Fmicb.2017.00713 |
0.314 |
|
| 2017 |
Gallo LH, Ko J, Donoghue DJ. The importance of regulatory ubiquitination in cancer and metastasis. Cell Cycle (Georgetown, Tex.). 0. PMID 28166483 DOI: 10.1080/15384101.2017.1288326 |
0.316 |
|
| 2016 |
Nelson KN, Peiris MN, Meyer AN, Siari A, Donoghue DJ. Receptor Tyrosine Kinases: Translocation Partners in Hematopoietic Disorders. Trends in Molecular Medicine. PMID 27988109 DOI: 10.1016/J.Molmed.2016.11.002 |
0.43 |
|
| 2016 |
Nelson KN, Meyer AN, Siari A, Campos AR, Motamedchaboki K, Donoghue DJ. Oncogenic Gene Fusion FGFR3-TACC3 is Regulated by Tyrosine Phosphorylation. Molecular Cancer Research : McR. PMID 26869289 DOI: 10.1158/1541-7786.Mcr-15-0497 |
0.427 |
|
| 2015 |
Gallo LH, Nelson KN, Meyer AN, Donoghue DJ. Functions of Fibroblast Growth Factor Receptors in cancer defined by novel translocations and mutations. Cytokine & Growth Factor Reviews. PMID 26003532 DOI: 10.1016/J.Cytogfr.2015.03.003 |
0.384 |
|
| 2014 |
Gallo LH, Meyer AN, Motamedchaboki K, Nelson KN, Haas M, Donoghue DJ. Novel Lys63-linked ubiquitination of IKKβ induces STAT3 signaling. Cell Cycle (Georgetown, Tex.). 13: 3964-76. PMID 25486864 DOI: 10.4161/15384101.2014.988026 |
0.386 |
|
| 2014 |
Salazar L, Kashiwada T, Krejci P, Meyer AN, Casale M, Hallowell M, Wilcox WR, Donoghue DJ, Thompson LM. Fibroblast growth factor receptor 3 interacts with and activates TGFβ-activated kinase 1 tyrosine phosphorylation and NFκB signaling in multiple myeloma and bladder cancer. Plos One. 9: e86470. PMID 24466111 DOI: 10.1371/Journal.Pone.0086470 |
0.406 |
|
| 2014 |
Manickam K, Donoghue DJ, Meyer AN, Snyder PJ, Prior TW. Suppression of severe achondroplasia with developmental delay and acanthosis nigricans by the p.Thr651Pro mutation. American Journal of Medical Genetics. Part A. 164: 243-50. PMID 24352917 DOI: 10.1002/Ajmg.A.36236 |
0.315 |
|
| 2013 |
Meyer AN, Drafahl KA, McAndrew CW, Gilda JE, Gallo LH, Haas M, Brill LM, Donoghue DJ. Tyrosine phosphorylation allows integration of multiple signaling inputs by IKKβ. Plos One. 8: e84497. PMID 24386391 DOI: 10.1371/Journal.Pone.0084497 |
0.77 |
|
| 2013 |
Locascio LE, Donoghue DJ. KIDs rule: regulatory phosphorylation of RTKs. Trends in Biochemical Sciences. 38: 75-84. PMID 23312584 DOI: 10.1016/J.Tibs.2012.12.001 |
0.394 |
|
| 2011 |
Fidalgo da Silva E, Ansari SB, Maimaiti J, Barnes EA, Kong-Beltran M, Donoghue DJ, Porter LA. The tumor suppressor tuberin regulates mitotic onset through the cellular localization of cyclin B1. Cell Cycle (Georgetown, Tex.). 10: 3129-39. PMID 21900748 DOI: 10.4161/Cc.10.18.17296 |
0.553 |
|
| 2010 |
Drafahl KA, McAndrew CW, Meyer AN, Haas M, Donoghue DJ. The receptor tyrosine kinase FGFR4 negatively regulates NF-kappaB signaling. Plos One. 5: e14412. PMID 21203561 DOI: 10.1371/Journal.Pone.0014412 |
0.762 |
|
| 2010 |
Drafahl KA, McAndrew CW, Donoghue DJ. Signaling from fibroblast growth factor receptors in development and disease Handbook of Cell Signaling, 2/E. 2: 1939-1947. DOI: 10.1016/B978-0-12-374145-5.00237-0 |
0.729 |
|
| 2009 |
Ahier A, Rondard P, Gouignard N, Khayath N, Huang S, Trolet J, Donoghue DJ, Gauthier M, Pin JP, Dissous C. A new family of receptor tyrosine kinases with a venus flytrap binding domain in insects and other invertebrates activated by aminoacids. Plos One. 4: e5651. PMID 19461966 DOI: 10.1371/Journal.Pone.0005651 |
0.36 |
|
| 2009 |
Salazar L, Kashiwada T, Krejci P, Muchowski P, Donoghue D, Wilcox WR, Thompson LM. A novel interaction between fibroblast growth factor receptor 3 and the p85 subunit of phosphoinositide 3-kinase: activation-dependent regulation of ERK by p85 in multiple myeloma cells. Human Molecular Genetics. 18: 1951-61. PMID 19286672 DOI: 10.1093/Hmg/Ddp116 |
0.392 |
|
| 2009 |
McAndrew CW, Gastwirt RF, Donoghue DJ. The atypical CDK activator Spy1 regulates the intrinsic DNA damage response and is dependent upon p53 to inhibit apoptosis. Cell Cycle (Georgetown, Tex.). 8: 66-75. PMID 19106603 DOI: 10.4161/Cc.8.1.7451 |
0.771 |
|
| 2008 |
Meyer AN, McAndrew CW, Donoghue DJ. Nordihydroguaiaretic acid inhibits an activated fibroblast growth factor receptor 3 mutant and blocks downstream signaling in multiple myeloma cells. Cancer Research. 68: 7362-70. PMID 18794123 DOI: 10.1158/0008-5472.Can-08-0575 |
0.794 |
|
| 2008 |
Golipour A, Myers D, Seagroves T, Murphy D, Evan GI, Donoghue DJ, Moorehead RA, Porter LA. The Spy1/RINGO family represents a novel mechanism regulating mammary growth and tumorigenesis. Cancer Research. 68: 3591-600. PMID 18483240 DOI: 10.1158/0008-5472.Can-07-6453 |
0.4 |
|
| 2007 |
McAndrew CW, Gastwirt RF, Meyer AN, Porter LA, Donoghue DJ. Spy1 enhances phosphorylation and degradation of the cell cycle inhibitor p27. Cell Cycle (Georgetown, Tex.). 6: 1937-45. PMID 17671428 DOI: 10.4161/Cc.6.15.4520 |
0.769 |
|
| 2007 |
Gastwirt RF, McAndrew CW, Donoghue DJ. Speedy/RINGO regulation of CDKs in cell cycle, checkpoint activation and apoptosis. Cell Cycle (Georgetown, Tex.). 6: 1188-93. PMID 17507798 DOI: 10.4161/Cc.6.10.4252 |
0.78 |
|
| 2006 |
Gastwirt RF, Slavin DA, McAndrew CW, Donoghue DJ. Spy1 expression prevents normal cellular responses to DNA damage: inhibition of apoptosis and checkpoint activation. The Journal of Biological Chemistry. 281: 35425-35. PMID 16951407 DOI: 10.1074/Jbc.M604720200 |
0.78 |
|
| 2005 |
Chen J, Williams IR, Lee BH, Duclos N, Huntly BJ, Donoghue DJ, Gilliland DG. Constitutively activated FGFR3 mutants signal through PLCgamma-dependent and -independent pathways for hematopoietic transformation. Blood. 106: 328-37. PMID 15784730 DOI: 10.1182/Blood-2004-09-3686 |
0.413 |
|
| 2005 |
Barnes EA, Heidtman KJ, Donoghue DJ. Constitutive activation of the shh-ptc1 pathway by a patched1 mutation identified in BCC. Oncogene. 24: 902-15. PMID 15592520 DOI: 10.1038/Sj.Onc.1208240 |
0.626 |
|
| 2004 |
Meyer AN, Gastwirt RF, Schlaepfer DD, Donoghue DJ. The cytoplasmic tyrosine kinase Pyk2 as a novel effector of fibroblast growth factor receptor 3 activation. The Journal of Biological Chemistry. 279: 28450-7. PMID 15105428 DOI: 10.1074/Jbc.M403335200 |
0.809 |
|
| 2003 |
Porter LA, Kong-Beltran M, Donoghue DJ. Spy1 interacts with p27Kip1 to allow G1/S progression. Molecular Biology of the Cell. 14: 3664-74. PMID 12972555 DOI: 10.1091/Mbc.E02-12-0820 |
0.447 |
|
| 2003 |
Barnes EA, Porter LA, Lenormand JL, Dellinger RW, Donoghue DJ. Human Spy1 promotes survival of mammalian cells following DNA damage. Cancer Research. 63: 3701-7. PMID 12839962 |
0.736 |
|
| 2002 |
Peter M, Le Peuch C, Labbé JC, Meyer AN, Donoghue DJ, Dorée M. Initial activation of cyclin-B1-cdc2 kinase requires phosphorylation of cyclin B1. Embo Reports. 3: 551-6. PMID 12034754 DOI: 10.1093/Embo-Reports/Kvf111 |
0.412 |
|
| 2002 |
Porter LA, Dellinger RW, Tynan JA, Barnes EA, Kong M, Lenormand JL, Donoghue DJ. Human Speedy: a novel cell cycle regulator that enhances proliferation through activation of Cdk2. The Journal of Cell Biology. 157: 357-66. PMID 11980914 DOI: 10.1083/Jcb.200109045 |
0.776 |
|
| 2002 |
Kong M, Wang CS, Donoghue DJ. Interaction of fibroblast growth factor receptor 3 and the adapter protein SH2-B. A role in STAT5 activation. The Journal of Biological Chemistry. 277: 15962-70. PMID 11827956 DOI: 10.1074/Jbc.M102777200 |
0.416 |
|
| 2001 |
Barnes EA, Kong M, Ollendorff V, Donoghue DJ. Patched1 interacts with cyclin B1 to regulate cell cycle progression. The Embo Journal. 20: 2214-23. PMID 11331587 DOI: 10.1093/Emboj/20.9.2214 |
0.602 |
|
| 2001 |
Hart KC, Robertson SC, Donoghue DJ. Identification of tyrosine residues in constitutively activated fibroblast growth factor receptor 3 involved in mitogenesis, Stat activation, and phosphatidylinositol 3-kinase activation. Molecular Biology of the Cell. 12: 931-42. PMID 11294897 DOI: 10.1091/Mbc.12.4.931 |
0.441 |
|
| 2000 |
Bellus GA, Spector EB, Speiser PW, Weaver CA, Garber AT, Bryke CR, Israel J, Rosengren SS, Webster MK, Donoghue DJ, Francomano CA. Distinct missense mutations of the FGFR3 lys650 codon modulate receptor kinase activation and the severity of the skeletal dysplasia phenotype. American Journal of Human Genetics. 67: 1411-21. PMID 11055896 DOI: 10.1086/316892 |
0.345 |
|
| 2000 |
Bell CA, Tynan JA, Hart KC, Meyer AN, Robertson SC, Donoghue DJ. Rotational coupling of the transmembrane and kinase domains of the Neu receptor tyrosine kinase. Molecular Biology of the Cell. 11: 3589-99. PMID 11029057 DOI: 10.1091/Mbc.11.10.3589 |
0.362 |
|
| 2000 |
Hart KC, Robertson SC, Kanemitsu MY, Meyer AN, Tynan JA, Donoghue DJ. Transformation and Stat activation by derivatives of FGFR1, FGFR3, and FGFR4. Oncogene. 19: 3309-20. PMID 10918587 DOI: 10.1038/Sj.Onc.1203650 |
0.445 |
|
| 2000 |
Hart KC, Robertson SC, Donoghue DJ. Activation of H-ras61L-specific signaling pathways does not require posttranslational processing of H-ras. Experimental Cell Research. 257: 89-100. PMID 10854057 DOI: 10.1006/Excr.2000.4874 |
0.316 |
|
| 2000 |
Robertson SC, Tynan JA, Donoghue DJ. RTK mutations and human syndromeswhen good receptors turn bad. Trends in Genetics : Tig. 16: 265-71. PMID 10827454 DOI: 10.1016/S0168-9525(00)02021-7 |
0.301 |
|
| 2000 |
Kong M, Barnes EA, Ollendorff V, Donoghue DJ. Cyclin F regulates the nuclear localization of cyclin B1 through a cyclin-cyclin interaction. The Embo Journal. 19: 1378-88. PMID 10716937 DOI: 10.1093/Emboj/19.6.1378 |
0.578 |
|
| 1999 |
Lenormand JL, Dellinger RW, Knudsen KE, Subramani S, Donoghue DJ. Speedy: a novel cell cycle regulator of the G2/M transition. The Embo Journal. 18: 1869-77. PMID 10202150 DOI: 10.1093/Emboj/18.7.1869 |
0.739 |
|
| 1999 |
Tavormina PL, Bellus GA, Webster MK, Bamshad MJ, Fraley AE, McIntosh I, Szabo J, Jiang W, Jabs EW, Wilcox WR, Wasmuth JJ, Donoghue DJ, Thompson LM, Francomano CA. A novel skeletal dysplasia with developmental delay and acanthosis nigricans is caused by a Lys650Met mutation in the fibroblast growth factor receptor 3 gene. American Journal of Human Genetics. 64: 722-31. PMID 10053006 DOI: 10.1086/302275 |
0.319 |
|
| 1998 |
Robertson SC, Meyer AN, Hart KC, Galvin BD, Webster MK, Donoghue DJ. Activating mutations in the extracellular domain of the fibroblast growth factor receptor 2 function by disruption of the disulfide bond in the third immunoglobulin-like domain. Proceedings of the National Academy of Sciences of the United States of America. 95: 4567-72. PMID 9539778 DOI: 10.1073/Pnas.95.8.4567 |
0.338 |
|
| 1997 |
Li J, Meyer AN, Donoghue DJ. Phosphorylation makes cyclin (B)eeline for the nucleus. Trends in Cell Biology. 7: 181. PMID 17708941 DOI: 10.1016/S0962-8924(97)84083-4 |
0.33 |
|
| 1997 |
Ollendorff V, Donoghue DJ. The serine/threonine phosphatase PP5 interacts with CDC16 and CDC27, two tetratricopeptide repeat-containing subunits of the anaphase-promoting complex. The Journal of Biological Chemistry. 272: 32011-8. PMID 9405394 DOI: 10.1074/Jbc.272.51.32011 |
0.351 |
|
| 1997 |
Webster MK, Donoghue DJ. Enhanced signaling and morphological transformation by a membrane-localized derivative of the fibroblast growth factor receptor 3 kinase domain. Molecular and Cellular Biology. 17: 5739-47. PMID 9315632 DOI: 10.1128/Mcb.17.10.5739 |
0.438 |
|
| 1997 |
Webster MK, Donoghue DJ. FGFR activation in skeletal disorders: too much of a good thing. Trends in Genetics : Tig. 13: 178-82. PMID 9154000 DOI: 10.1016/S0168-9525(97)01131-1 |
0.352 |
|
| 1997 |
Chen LI, Webster MK, Meyer AN, Donoghue DJ. Transmembrane domain sequence requirements for activation of the p185c-neu receptor tyrosine kinase. The Journal of Cell Biology. 137: 619-31. PMID 9151669 DOI: 10.1083/Jcb.137.3.619 |
0.343 |
|
| 1997 |
Li J, Meyer AN, Donoghue DJ. Nuclear localization of cyclin B1 mediates its biological activity and is regulated by phosphorylation. Proceedings of the National Academy of Sciences of the United States of America. 94: 502-7. PMID 9012813 DOI: 10.1073/Pnas.94.2.502 |
0.447 |
|
| 1996 |
Galvin BD, Hart KC, Meyer AN, Webster MK, Donoghue DJ. Constitutive receptor activation by Crouzon syndrome mutations in fibroblast growth factor receptor (FGFR)2 and FGFR2/Neu chimeras. Proceedings of the National Academy of Sciences of the United States of America. 93: 7894-9. PMID 8755573 DOI: 10.1073/Pnas.93.15.7894 |
0.371 |
|
| 1996 |
Webster MK, D'Avis PY, Robertson SC, Donoghue DJ. Profound ligand-independent kinase activation of fibroblast growth factor receptor 3 by the activation loop mutation responsible for a lethal skeletal dysplasia, thanatophoric dysplasia type II. Molecular and Cellular Biology. 16: 4081-7. PMID 8754806 DOI: 10.1128/Mcb.16.8.4081 |
0.394 |
|
| 1996 |
Robertson SC, Donoghue DJ. Identification of an autoinhibitory region in the activation loop of the Mos protein kinase. Molecular and Cellular Biology. 16: 3472-9. PMID 8668163 DOI: 10.1128/Mcb.16.7.3472 |
0.432 |
|
| 1996 |
Webster MK, Donoghue DJ. Constitutive activation of fibroblast growth factor receptor 3 by the transmembrane domain point mutation found in achondroplasia. The Embo Journal. 15: 520-7. PMID 8599935 DOI: 10.1002/J.1460-2075.1996.Tb00384.X |
0.378 |
|
| 1995 |
Li J, Meyer AN, Donoghue DJ. Requirement for phosphorylation of cyclin B1 for Xenopus oocyte maturation. Molecular Biology of the Cell. 6: 1111-24. PMID 8534910 DOI: 10.1091/Mbc.6.9.1111 |
0.402 |
|
| 1994 |
Meyer AN, Xu YF, Webster MK, Smith AE, Donoghue DJ. Cellular transformation by a transmembrane peptide: structural requirements for the bovine papillomavirus E5 oncoprotein. Proceedings of the National Academy of Sciences of the United States of America. 91: 4634-8. PMID 8197111 DOI: 10.1073/Pnas.91.11.4634 |
0.351 |
|
| 1994 |
Pickham KM, Donoghue DJ. Mutants at Ser277 of Xenopus cdc2 protein kinase induce oocyte maturation in the absence of the positive regulatory phosphorylation site Thr161. Molecular Biology of the Cell. 5: 587-96. PMID 7919539 DOI: 10.1091/Mbc.5.5.587 |
0.399 |
|
| 1994 |
Hart KC, Xu YF, Meyer AN, Lee BA, Donoghue DJ. The v-sis oncoprotein loses transforming activity when targeted to the early Golgi complex. The Journal of Cell Biology. 127: 1843-57. PMID 7806564 DOI: 10.1083/Jcb.127.6.1843 |
0.335 |
|
| 1993 |
Xu YF, Meyer AN, Webster MK, Lee BA, Donoghue DJ. The v-sis protein retains biological activity as a type II membrane protein when anchored by various signal-anchor domains, including the hydrophobic domain of the bovine papilloma virus E5 oncoprotein. The Journal of Cell Biology. 123: 549-60. PMID 8227125 DOI: 10.1083/Jcb.123.3.549 |
0.336 |
|
| 1992 |
Freeman RS, Meyer AN, Li J, Donoghue DJ. Phosphorylation of conserved serine residues does not regulate the ability of mosxe protein kinase to induce oocyte maturation or function as cytostatic factor. The Journal of Cell Biology. 116: 725-35. PMID 1530949 DOI: 10.1083/Jcb.116.3.725 |
0.625 |
|
| 1992 |
Pickham KM, Meyer AN, Li J, Donoghue DJ. Requirement of mosXe protein kinase for meiotic maturation of Xenopus oocytes induced by a cdc2 mutant lacking regulatory phosphorylation sites. Molecular and Cellular Biology. 12: 3192-203. PMID 1377775 DOI: 10.1128/Mcb.12.7.3192 |
0.421 |
|
| 1992 |
Lee BA, Donoghue DJ. Intracellular retention of membrane-anchored v-sis protein abrogates autocrine signal transduction. The Journal of Cell Biology. 118: 1057-70. PMID 1324943 DOI: 10.1083/Jcb.118.5.1057 |
0.363 |
|
| 1992 |
Lee MS, Ogg S, Xu M, Parker LL, Donoghue DJ, Maller JL, Piwnica-Worms H. cdc25+ encodes a protein phosphatase that dephosphorylates p34cdc2. Molecular Biology of the Cell. 3: 73-84. PMID 1312880 DOI: 10.1091/Mbc.3.1.73 |
0.428 |
|
| 1991 |
Freeman RS, Donoghue DJ. Protein kinases and protooncogenes: biochemical regulators of the eukaryotic cell cycle. Biochemistry. 30: 2293-302. PMID 2001361 DOI: 10.1021/Bi00223A001 |
0.602 |
|
| 1991 |
Lee BA, Donoghue DJ. Membrane-anchored form of v-SIS/PDGF-B induces mitogenesis without detectable PDGF receptor autophosphorylation Journal of Cell Biology. 113: 361-370. PMID 1849139 DOI: 10.1083/Jcb.113.2.361 |
0.362 |
|
| 1991 |
Freeman RS, Ballantyne SM, Donoghue DJ. Meiotic induction by Xenopus cyclin B is accelerated by coexpression with mosXe. Molecular and Cellular Biology. 11: 1713-7. PMID 1825350 DOI: 10.1128/Mcb.11.3.1713 |
0.561 |
|
| 1991 |
Kanki JP, Donoghue DJ. Progression from meiosis I to meiosis II in Xenopus oocytes requires de novo translation of the mosxe protooncogene Proceedings of the National Academy of Sciences of the United States of America. 88: 5794-5798. PMID 1648231 DOI: 10.1073/Pnas.88.13.5794 |
0.357 |
|
| 1990 |
Freeman RS, Kanki JP, Ballantyne SM, Pickham KM, Donoghue DJ. Effects of the v-mos oncogene on Xenopus development: meiotic induction in oocytes and mitotic arrest in cleaving embryos. The Journal of Cell Biology. 111: 533-41. PMID 2143197 DOI: 10.1083/Jcb.111.2.533 |
0.586 |
|
| 1989 |
Maher DW, Lee BA, Donoghue DJ. The alternatively spliced exon of the platelet-derived growth factor A chain encodes a nuclear targeting signal Molecular and Cellular Biology. 9: 2251-2253. PMID 2747650 DOI: 10.1128/Mcb.9.5.2251 |
0.314 |
|
| 1989 |
Hannink M, Donoghue DJ. Structure and function of platelet-derived growth factor (PDGF) and related proteins Bba - Reviews On Cancer. 989: 1-10. PMID 2546599 DOI: 10.1016/0304-419X(89)90031-0 |
0.581 |
|
| 1989 |
Freeman RS, Donoghue DJ. Transforming mutant v-mos protein kinases that are deficient in in vitro autophosphorylation. Molecular and Cellular Biology. 9: 4087-90. PMID 2528689 DOI: 10.1128/Mcb.9.9.4087 |
0.608 |
|
| 1989 |
Freeman RS, Pickham KM, Kanki JP, Lee BA, Pena SV, Donoghue DJ. Xenopus homolog of the mos protooncogene transforms mammalian fibroblasts and induces maturation of Xenopus oocytes. Proceedings of the National Academy of Sciences of the United States of America. 86: 5805-9. PMID 2527365 DOI: 10.1073/Pnas.86.15.5805 |
0.609 |
|
| 1988 |
Singh B, Wittenberg C, Hannink M, Reed SI, Donoghue DJ, Arlinghaus RB. The histidine-221 to tyrosine substitution in v-mos abolishes its biological function and its protein kinase activity. Virology. 164: 114-20. PMID 2966489 DOI: 10.1016/0042-6822(88)90626-5 |
0.674 |
|
| 1988 |
Sauer MK, Donoghue DJ. Identification of nonessential disulfide bonds and altered conformations in the v-sis protein, a homolog of the B chain of platelet-derived growth factor Molecular and Cellular Biology. 8: 1011-1018. PMID 2835654 DOI: 10.1128/Mcb.8.3.1011 |
0.332 |
|
| 1988 |
Hannink M, Donoghue DJ. Autocrine stimulation by the v-sis gene product requires a ligand-receptor interaction at the cell surface Journal of Cell Biology. 107: 287-298. PMID 2455725 DOI: 10.1083/Jcb.107.1.287 |
0.63 |
|
| 1987 |
Lee BA, Maher DW, Hannink M, Donoghue DJ. Identification of a signal for nuclear targeting in platelet-derived-growth-factor-related molecules Molecular and Cellular Biology. 7: 3527-3537. PMID 3316980 DOI: 10.1128/Mcb.7.10.3527 |
0.636 |
|
| 1986 |
Hannink M, Sauer MK, Donoghue DJ. Deletions in the C-terminal coding region of the v-sis gene: Dimerization is required for transformation Molecular and Cellular Biology. 6: 1304-1314. PMID 3785165 DOI: 10.1128/Mcb.6.4.1304 |
0.598 |
|
| 1986 |
Hannink M, Donoghue DJ. Biosynthesis of the v-sis gene product: Signal sequence cleavage, glycosylation, and proteolytic processing Molecular and Cellular Biology. 6: 1343-1348. PMID 3537701 DOI: 10.1128/Mcb.6.4.1343 |
0.613 |
|
| 1986 |
Hannink M, Donoghue DJ. Cell surface expression of membrane-anchored v-sis gene products: Glycosylation is not required for cell surface transport Journal of Cell Biology. 103: 2311-2322. PMID 3536965 DOI: 10.1083/Jcb.103.6.2311 |
0.614 |
|
| 1986 |
Sauer MK, Hannink M, Donoghue DJ. Deletions in the N-terminal coding region of the v-sis gene: Determination of the minimal transforming region Journal of Virology. 59: 292-300. PMID 3525855 DOI: 10.1128/Jvi.59.2.292-300.1986 |
0.608 |
|
| 1986 |
Singh B, Hannink M, Donoghue DJ, Arlinghaus RB. p37mos-associated serine/threonine protein kinase activity correlates with the cellular transformation function of v-mos. Journal of Virology. 60: 1148-1152. DOI: 10.1128/jvi.60.3.1148-1152.1986 |
0.612 |
|
| 1985 |
Bold RJ, Donoghue DJ. Biologically active mutants with deletions in the v-mos oncogene assayed with retroviral vectors Molecular and Cellular Biology. 5: 3131-3138. PMID 3018503 DOI: 10.1128/Mcb.5.11.3131 |
0.345 |
|
| 1985 |
Hannink M, Donoghue DJ. Lysine residue 121 in the proposed ATP-binding site of the v-mos protein is required for transformation Proceedings of the National Academy of Sciences of the United States of America. 82: 7894-7898. PMID 2999782 DOI: 10.1073/Pnas.82.23.7894 |
0.65 |
|
| 1984 |
Donoghue DJ, Anderson C, Hunter T, Kaplan PL. Transmission of the polyoma virus middle T gene as the oncogene of a murine retrovirus. Nature. 308: 748-50. PMID 6325917 DOI: 10.1038/308748A0 |
0.436 |
|
| 1984 |
Hannink M, Donoghue DJ. Requirement for a signal sequence in biological expression of the v-sis oncogene Science. 226: 1197-1199. PMID 6095451 DOI: 10.1126/Science.6095451 |
0.616 |
|
| 1983 |
Donoghue DJ, Hunter T. Recombinational junctions of variants of Moloney murine sarcoma virus: generation and divergence of a mammalian transforming gene. Journal of Virology. 45: 607-17. PMID 6300424 DOI: 10.1128/Jvi.45.2.607-617.1983 |
0.435 |
|
| 1982 |
Donoghue DJ, Hunter T. A generalized method of subcloning DNA fragments by restriction site reconstruction: application to sequencing the amino-terminal coding region of the transforming gene of Gazdar murine sarcoma virus. Nucleic Acids Research. 10: 2549-64. PMID 6281735 DOI: 10.1093/Nar/10.8.2549 |
0.36 |
|
| 1982 |
Donoghue DJ, Hunter T. Expression of transforming region of Moloney murine sarcoma virus in Escherichia coli as a fusion protein with small tumor antigen of polyoma virus. Proceedings of the National Academy of Sciences of the United States of America. 79: 800-4. PMID 6278495 DOI: 10.1073/Pnas.79.3.800 |
0.449 |
|
| 1980 |
Donoghue DJ, Goldfarb MP, Sharp PA, Weinberg RA. Organization of murine sarcoma virus genomes. Cold Spring Harbor Symposia On Quantitative Biology. 44: 721-6. PMID 6253206 DOI: 10.1101/Sqb.1980.044.01.077 |
0.319 |
|
| 1979 |
Donoghue DJ, Sharp PA, Weinberg RA. An MSV-specific subgenomic mRNA in MSV-transformed G8-124 cells. Cell. 17: 53-63. PMID 556552 DOI: 10.1016/0092-8674(79)90294-0 |
0.345 |
|
| 1979 |
Donoghue DJ, Sharp PA, Weinberg RA. Comparative study of different isolates of murine sarcoma virus. Journal of Virology. 32: 1015-27. PMID 229256 DOI: 10.1128/Jvi.32.3.1015-1027.1979 |
0.375 |
|
| 1979 |
Donoghue DJ, Sharp PA, Weinberg RA. Comparative study of different isolates of murine sarcoma virus. Journal of Virology. 32: 1015-1027. DOI: 10.1128/jvi.32.3.1015-1027.1979 |
0.33 |
|
| 1978 |
Donoghue DJ, Sharp PA. Construction of a hybrid bacteriophage-plasmid recombinant DNA vector. Journal of Bacteriology. 136: 1192-6. PMID 363694 DOI: 10.1128/Jb.136.3.1192-1196.1978 |
0.371 |
|
| 1978 |
Donoghue DJ, Sharp PA. Replication of colicin E1 plasmid DNA in vivo requires no plasmid-encoded proteins. Journal of Bacteriology. 133: 1287-94. PMID 346567 DOI: 10.1128/Jb.133.3.1287-1294.1978 |
0.386 |
|
| 1978 |
Donoghue DJ, Rothenberg E, Hopkins N, Baltimore D, Sharp PA. Heteroduplex analysis of the nonhomology region between Moloney MuLV and the dual host range derivative HIX virus. Cell. 14: 959-70. PMID 210960 DOI: 10.1016/0092-8674(78)90350-1 |
0.355 |
|
| 1977 |
Donoghue DJ, Sharp PA. An improved bacteriophage lambda vector: construction of model recombinants coding for kanamycin resistance. Gene. 1: 209-27. PMID 338417 DOI: 10.1016/0378-1119(77)90046-4 |
0.38 |
|
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