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Huban Kutay, Ph.D. - Publications

Affiliations: 
2006 Ohio State University, Columbus, Columbus, OH 
Area:
Sciences Education, Sociology of Education, Bilingual and Multicultural Education
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34 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Ju C, Wang M, Tak E, Kim B, Emontzpohl C, Yang Y, Yuan X, Kutay H, Liang Y, Hall DR, Dar WA, Bynon JS, Carmeliet P, Ghoshal K, Eltzschig HK. Hypoxia-inducible factor-1α-dependent induction of miR122 enhances hepatic ischemia tolerance. The Journal of Clinical Investigation. 131. PMID 33792566 DOI: 10.1172/JCI140300  0.392
2018 Nasser MW, Datta J, Nuovo G, Kutay H, Motiwala T, Majumder S, Wang B, Suster S, Jacob ST, Ghoshal K. Down-regulation of micro-RNA-1 (miR-1) in lung cancer. Suppression of tumorigenic property of lung cancer cells and their sensitization to doxorubicin-induced apoptosis by miR-1. The Journal of Biological Chemistry. 293: 12945. PMID 30120149 DOI: 10.1074/Jbc.W118.004967  0.441
2016 Sun HL, Cui R, Zhou J, Teng KY, Hsiao YH, Nakanishi K, Fassan M, Luo Z, Shi G, Tili E, Kutay H, Lovat F, Vicentini C, Huang HL, Wang SW, et al. ERK Activation Globally Downregulates miRNAs through Phosphorylating Exportin-5. Cancer Cell. 30: 723-736. PMID 27846390 DOI: 10.1016/J.Ccell.2016.10.001  0.347
2016 Valdmanis PN, Gu S, Chu K, Jin L, Zhang F, Munding EM, Zhang Y, Huang Y, Kutay H, Ghoshal K, Lisowski L, Kay MA. RNA interference-induced hepatotoxicity results from loss of the first synthesized isoform of microRNA-122 in mice. Nature Medicine. PMID 27064447 DOI: 10.1038/Nm.4079  0.486
2016 Hsu SH, Delgado ER, Otero PA, Teng KY, Kutay H, Meehan KM, Moroney JB, Monga JK, Hand NJ, Friedman JR, Ghoshal K, Duncan AW. MicroRNA-122 Regulates Polyploidization in the Murine Liver. Hepatology (Baltimore, Md.). PMID 27016325 DOI: 10.1002/Hep.28573  0.475
2016 Valdmanis PN, Gu S, Chu K, Jin L, Zhang F, Munding EM, Zhang Y, Huang Y, Kutay H, Ghoshal K, Lisowski L, Kay MA. 737. RNAi Induced Hepatotoxicity Results from a Functional Depletion of the First Synthesized Isoform of miR-122 Molecular Therapy. 24: S290-S291. DOI: 10.1016/S1525-0016(16)33545-6  0.487
2015 Motiwala T, Kutay H, Zanesi N, Frissora FW, Mo X, Muthusamy N, Jacob ST. PTPROt-mediated regulation of p53/Foxm1 suppresses leukemic phenotype in a CLL mouse model. Leukemia. 29: 1350-9. PMID 25482129 DOI: 10.1038/Leu.2014.341  0.436
2014 Wang B, Hsu SH, Wang X, Kutay H, Bid HK, Yu J, Ganju RK, Jacob ST, Yuneva M, Ghoshal K. Reciprocal regulation of microRNA-122 and c-Myc in hepatocellular cancer: role of E2F1 and transcription factor dimerization partner 2. Hepatology (Baltimore, Md.). 59: 555-66. PMID 24038073 DOI: 10.1002/Hep.26712  0.524
2014 Motiwala T, Mustafa M, Kutay H, Sullivan RC, Teng K, Chowdhary V, Yu L, Ghoshal K, Jacob ST. Abstract 4359: Elucidation of the role of microRNA-155 in a murine model of non-alcoholic steatohepatitis Cancer Research. 74: 4359-4359. DOI: 10.1158/1538-7445.Am2014-4359  0.517
2013 Hsu SH, Wang B, Kutay H, Bid H, Shreve J, Zhang X, Costinean S, Bratasz A, Houghton P, Ghoshal K. Hepatic loss of miR-122 predisposes mice to hepatobiliary cyst and hepatocellular carcinoma upon diethylnitrosamine exposure. The American Journal of Pathology. 183: 1719-30. PMID 24113455 DOI: 10.1016/J.Ajpath.2013.08.004  0.504
2012 Kutay H, Klepper C, Wang B, Hsu SH, Datta J, Yu L, Zhang X, Majumder S, Motiwala T, Khan N, Belury M, McClain C, Jacob S, Ghoshal K. Reduced susceptibility of DNA methyltransferase 1 hypomorphic (Dnmt1N/+) mice to hepatic steatosis upon feeding liquid alcohol diet. Plos One. 7: e41949. PMID 22905112 DOI: 10.1371/Journal.Pone.0041949  0.323
2012 Hsu SH, Wang B, Kota J, Yu J, Costinean S, Kutay H, Yu L, Bai S, La Perle K, Chivukula RR, Mao H, Wei M, Clark KR, Mendell JR, Caligiuri MA, et al. Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver. The Journal of Clinical Investigation. 122: 2871-83. PMID 22820288 DOI: 10.1172/Jci63539  0.489
2012 Motiwala T, Zanesi N, Roy S, Mustafa M, Kutay H, You J, Frissora F, Lu Y, Muthusamy N, Freitas M, Croce CM, Jacob ST. Abstract 1351: Analysis of the in vivo tumor suppressive potential of PTPROt (truncated protein tyrosine phosphatase receptor-type O) in CLL using a transgenic mouse model Cancer Research. 72: 1351-1351. DOI: 10.1158/1538-7445.Am2012-1351  0.418
2011 Motiwala T, Zanesi N, Datta J, Roy S, Kutay H, Checovich AM, Kaou M, Zhong Y, Johnson AJ, Lucas DM, Heerema NA, Hagan J, Mo X, Jarjoura D, Byrd JC, et al. AP-1 elements and TCL1 protein regulate expression of the gene encoding protein tyrosine phosphatase PTPROt in leukemia. Blood. 118: 6132-40. PMID 22001392 DOI: 10.1182/Blood-2011-01-323147  0.431
2011 Hsu S, Wang B, Costinean S, Bai S, Kutay H, Yu L, Nuovo G, Jacob S, Ghoshal K. Abstract 2810: Loss of microRNA-122 in mice causes hepatic inflammation and hepatocarcinogenesis Cancer Research. 71: 2810-2810. DOI: 10.1158/1538-7445.Am2011-2810  0.489
2011 Motiwala T, Datta J, Kutay H, Roy S, Checovich A, Zanesi N, Kaou M, Johnson A, Hagan J, Byrd JC, Croce CM, Jacob ST. Abstract 276: Role of AP1 elements and TCL1 protein in regulation of the gene encoding PTPROt (protein tyrosine phosphatase receptor-type O) in chronic lymphocytic leukemia Cancer Research. 71: 276-276. DOI: 10.1158/1538-7445.Am2011-276  0.458
2010 Motiwala T, Datta J, Kutay H, Roy S, Jacob ST. Lyn kinase and ZAP70 are substrates of PTPROt in B-cells: Lyn inactivation by PTPROt sensitizes leukemia cells to VEGF-R inhibitor pazopanib. Journal of Cellular Biochemistry. 110: 846-56. PMID 20564182 DOI: 10.1002/Jcb.22593  0.362
2010 Ghoshal K, Motiwala T, Claus R, Yan P, Kutay H, Datta J, Majumder S, Bai S, Majumder A, Huang T, Plass C, Jacob ST. HOXB13, a target of DNMT3B, is methylated at an upstream CpG island, and functions as a tumor suppressor in primary colorectal tumors. Plos One. 5: e10338. PMID 20454457 DOI: 10.1371/Journal.Pone.0010338  0.348
2010 Wang B, Hsu SH, Majumder S, Kutay H, Huang W, Jacob ST, Ghoshal K. TGFbeta-mediated upregulation of hepatic miR-181b promotes hepatocarcinogenesis by targeting TIMP3. Oncogene. 29: 1787-97. PMID 20023698 DOI: 10.1038/Onc.2009.468  0.52
2009 Bai S, Nasser MW, Wang B, Hsu SH, Datta J, Kutay H, Yadav A, Nuovo G, Kumar P, Ghoshal K. MicroRNA-122 inhibits tumorigenic properties of hepatocellular carcinoma cells and sensitizes these cells to sorafenib. The Journal of Biological Chemistry. 284: 32015-27. PMID 19726678 DOI: 10.1074/Jbc.M109.016774  0.519
2009 Wang B, Majumder S, Nuovo G, Kutay H, Volinia S, Patel T, Schmittgen TD, Croce C, Ghoshal K, Jacob ST. Role of microRNA-155 at early stages of hepatocarcinogenesis induced by choline-deficient and amino acid-defined diet in C57BL/6 mice. Hepatology (Baltimore, Md.). 50: 1152-61. PMID 19711427 DOI: 10.1002/Hep.23100  0.527
2009 Ramaswamy B, Majumder S, Roy S, Ghoshal K, Kutay H, Datta J, Younes M, Shapiro CL, Motiwala T, Jacob ST. Estrogen-mediated suppression of the gene encoding protein tyrosine phosphatase PTPRO in human breast cancer: mechanism and role in tamoxifen sensitivity. Molecular Endocrinology (Baltimore, Md.). 23: 176-87. PMID 19095770 DOI: 10.1210/Me.2008-0211  0.382
2009 Motiwala T, Majumder S, Ghoshal K, Kutay H, Datta J, Roy S, Lucas DM, Jacob ST. PTPROt inactivates the oncogenic fusion protein BCR/ABL and suppresses transformation of K562 cells. The Journal of Biological Chemistry. 284: 455-64. PMID 18997174 DOI: 10.1074/Jbc.M802840200  0.393
2008 Nasser MW, Datta J, Nuovo G, Kutay H, Motiwala T, Majumder S, Wang B, Suster S, Jacob ST, Ghoshal K. Down-regulation of micro-RNA-1 (miR-1) in lung cancer. Suppression of tumorigenic property of lung cancer cells and their sensitization to doxorubicin-induced apoptosis by miR-1. The Journal of Biological Chemistry. 283: 33394-405. PMID 18818206 DOI: 10.1074/Jbc.M804788200  0.514
2008 Datta J, Kutay H, Nasser MW, Nuovo GJ, Wang B, Majumder S, Liu CG, Volinia S, Croce CM, Schmittgen TD, Ghoshal K, Jacob ST. Methylation mediated silencing of MicroRNA-1 gene and its role in hepatocellular carcinogenesis. Cancer Research. 68: 5049-58. PMID 18593903 DOI: 10.1158/0008-5472.Can-07-6655  0.54
2007 Motiwala T, Majumder S, Kutay H, Smith DS, Neuberg DS, Lucas DM, Byrd JC, Grever M, Jacob ST. Methylation and silencing of protein tyrosine phosphatase receptor type O in chronic lymphocytic leukemia. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 3174-81. PMID 17545520 DOI: 10.1158/1078-0432.Ccr-06-1720  0.399
2007 Datta J, Majumder S, Kutay H, Motiwala T, Frankel W, Costa R, Cha HC, MacDougald OA, Jacob ST, Ghoshal K. Metallothionein expression is suppressed in primary human hepatocellular carcinomas and is mediated through inactivation of CCAAT/enhancer binding protein alpha by phosphatidylinositol 3-kinase signaling cascade. Cancer Research. 67: 2736-46. PMID 17363595 DOI: 10.1158/0008-5472.Can-06-4433  0.416
2007 Majumder S, Motiwala T, Ghoshal K, Kutay H, Datta J, Lucas D, Byrd JC, Jacob ST. Protein Tyrosine Phosphatase Receptor Type O (PTPRO) Exhibits Tumor Suppressor Properties in K562 Cells by Dephosphorylating Bcr-Abl. Blood. 110: 2914-2914. DOI: 10.1182/Blood.V110.11.2914.2914  0.41
2006 Kutay H, Bai S, Datta J, Motiwala T, Pogribny I, Frankel W, Jacob ST, Ghoshal K. Downregulation of miR-122 in the rodent and human hepatocellular carcinomas. Journal of Cellular Biochemistry. 99: 671-8. PMID 16924677 DOI: 10.1002/Jcb.20982  0.492
2006 Majumder S, Kutay H, Datta J, Summers D, Jacob ST, Ghoshal K. Epigenetic regulation of metallothionein-i gene expression: differential regulation of methylated and unmethylated promoters by DNA methyltransferases and methyl CpG binding proteins. Journal of Cellular Biochemistry. 97: 1300-16. PMID 16329111 DOI: 10.1002/Jcb.20738  0.349
2005 Datta J, Majumder S, Bai S, Ghoshal K, Kutay H, Smith DS, Crabb JW, Jacob ST. Physical and functional interaction of DNA methyltransferase 3A with Mbd3 and Brg1 in mouse lymphosarcoma cells. Cancer Research. 65: 10891-900. PMID 16322236 DOI: 10.1158/0008-5472.Can-05-1455  0.358
2005 Ghoshal K, Datta J, Majumder S, Bai S, Kutay H, Motiwala T, Jacob ST. 5-Aza-deoxycytidine induces selective degradation of DNA methyltransferase 1 by a proteasomal pathway that requires the KEN box, bromo-adjacent homology domain, and nuclear localization signal. Molecular and Cellular Biology. 25: 4727-41. PMID 15899874 DOI: 10.1128/Mcb.25.11.4727-4741.2005  0.357
2004 Motiwala T, Kutay H, Ghoshal K, Bai S, Seimiya H, Tsuruo T, Suster S, Morrison C, Jacob ST. Protein tyrosine phosphatase receptor-type O (PTPRO) exhibits characteristics of a candidate tumor suppressor in human lung cancer. Proceedings of the National Academy of Sciences of the United States of America. 101: 13844-9. PMID 15356345 DOI: 10.1073/Pnas.0405451101  0.373
2004 Motiwala T, Ghoshal K, Majumder S, Kutay H, Neuberg DS, Kitada S, Reed JC, Dewald GW, Flinn IW, Tallman MA, Liu T, Plass C, Lucas DM, Byrd JC, Jacob ST, et al. Methylation of the Tumor Suppressor Gene PTPRO (Receptor-Type Protein Tyrosine Phosphatase) Is Associated with Expression of Important Apoptosis-Related Proteins in Chronic Lymphocytic Leukemia (CLL). Blood. 104: 2804-2804. DOI: 10.1182/Blood.V104.11.2804.2804  0.395
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