Jonathan R. Beckwith - Publications

Affiliations: 
Harvard Medical School, Boston, MA, United States 
Area:
bacterial genetics
Website:
http://beck2.med.harvard.edu/people/people.htm

79 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Meehan BM, Landeta C, Boyd D, Beckwith J. The Disulfide Bond Formation Pathway is Essential for Anaerobic Growth of Escherichia coli. Journal of Bacteriology. PMID 28559299 DOI: 10.1128/Jb.00120-17  0.391
2015 Hatahet F, Blazyk JL, Martineau E, Mandela E, Zhao Y, Campbell RE, Beckwith J, Boyd D. Altered Escherichia coli membrane protein assembly machinery allows proper membrane assembly of eukaryotic protein vitamin K epoxide reductase. Proceedings of the National Academy of Sciences of the United States of America. PMID 26598701 DOI: 10.1073/Pnas.1521260112  0.394
2015 Williamson JA, Cho SH, Ye J, Collet JF, Beckwith JR, Chou JJ. Structure and multistate function of the transmembrane electron transporter CcdA. Nature Structural & Molecular Biology. PMID 26389738 DOI: 10.1038/Nsmb.3099  0.331
2014 Dwyer RS, Malinverni JC, Boyd D, Beckwith J, Silhavy TJ. Folding LacZ in the periplasm of Escherichia coli Journal of Bacteriology. 196: 3343-3350. DOI: 10.1128/JB.01843-14  0.77
2013 Beckwith J. Fifty years fused to lac Annual Review of Microbiology. 67: 1-19. PMID 24024632 DOI: 10.1146/Annurev-Micro-092412-155732  0.387
2012 Chng SS, Xue M, Garner RA, Kadokura H, Boyd D, Beckwith J, Kahne D. Disulfide rearrangement triggered by translocon assembly controls lipopolysaccharide export. Science (New York, N.Y.). 337: 1665-8. PMID 22936569 DOI: 10.1126/Science.1227215  0.383
2012 Chng SS, Dutton RJ, Denoncin K, Vertommen D, Collet JF, Kadokura H, Beckwith J. Overexpression of the rhodanese PspE, a single cysteine-containing protein, restores disulphide bond formation to an Escherichia coli strain lacking DsbA. Molecular Microbiology. 85: 996-1006. PMID 22809289 DOI: 10.1111/J.1365-2958.2012.08157.X  0.356
2012 Cho SH, Parsonage D, Thurston C, Dutton RJ, Poole LB, Collet JF, Beckwith J. A new family of membrane electron transporters and its substrates, including a new cell envelope peroxiredoxin, reveal a broadened reductive capacity of the oxidative bacterial cell envelope. Mbio. 3. PMID 22493033 DOI: 10.1128/Mbio.00291-11  0.403
2012 Feeney MA, Ke N, Beckwith J. Mutations at several loci cause increased expression of ribonucleotide reductase in Escherichia coli. Journal of Bacteriology. 194: 1515-22. PMID 22247510 DOI: 10.1128/Jb.05989-11  0.79
2011 Feeney MA, Veeravalli K, Boyd D, Gon S, Faulkner MJ, Georgiou G, Beckwith J. Repurposing lipoic acid changes electron flow in two important metabolic pathways of Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 108: 7991-6. PMID 21521794 DOI: 10.1073/Pnas.1105429108  0.766
2010 Huber D, Chaffotte A, Eser M, Planson AG, Beckwith J. Amino acid residues important for folding of thioredoxin are revealed only by study of the physiologically relevant reduced form of the protein. Biochemistry. 49: 8922-8. PMID 20873718 DOI: 10.1021/Bi100784H  0.677
2010 Beckwith J, Herskowitz I, Ptashne M, Signer E, Thomas R. Political discussions at gordon conference. Science (New York, N.Y.). 171: 752. PMID 17812018 DOI: 10.1126/Science.171.3973.752  0.609
2009 Eser M, Masip L, Kadokura H, Georgiou G, Beckwith J. Disulfide bond formation by exported glutaredoxin indicates glutathione's presence in the E. coli periplasm. Proceedings of the National Academy of Sciences of the United States of America. 106: 1572-7. PMID 19164554 DOI: 10.1073/Pnas.0812596106  0.344
2008 Robichon C, King GF, Goehring NW, Beckwith J. Artificial septal targeting of Bacillus subtilis cell division proteins in Escherichia coli: an interspecies approach to the study of protein-protein interactions in multiprotein complexes. Journal of Bacteriology. 190: 6048-59. PMID 18621900 DOI: 10.1128/Jb.00462-08  0.711
2008 Faulkner MJ, Veeravalli K, Gon S, Georgiou G, Beckwith J. Functional plasticity of a peroxidase allows evolution of diverse disulfide-reducing pathways. Proceedings of the National Academy of Sciences of the United States of America. 105: 6735-40. PMID 18456836 DOI: 10.1073/Pnas.0801986105  0.788
2008 Yamamoto Y, Ritz D, Planson AG, Jönsson TJ, Faulkner MJ, Boyd D, Beckwith J, Poole LB. Mutant AhpC peroxiredoxins suppress thiol-disulfide redox deficiencies and acquire deglutathionylating activity. Molecular Cell. 29: 36-45. PMID 18206967 DOI: 10.1016/J.Molcel.2007.11.029  0.768
2007 Goehring NW, Robichon C, Beckwith J. Role for the nonessential N terminus of FtsN in divisome assembly. Journal of Bacteriology. 189: 646-9. PMID 17071748 DOI: 10.1128/Jb.00992-06  0.7
2007 Goehring NW, Petrovska I, Boyd D, Beckwith J. Mutants, suppressors, and wrinkled colonies: mutant alleles of the cell division gene ftsQ point to functional domains in FtsQ and a role for domain 1C of FtsA in divisome assembly. Journal of Bacteriology. 189: 633-45. PMID 16980443 DOI: 10.1128/Jb.00991-06  0.723
2006 Huber D, Beckwith J. Phage display extends its reach. Nature Biotechnology. 24: 793-4. PMID 16841063 DOI: 10.1038/Nbt0706-793  0.637
2006 Goehring NW, Gonzalez MD, Beckwith J. Premature targeting of cell division proteins to midcell reveals hierarchies of protein interactions involved in divisome assembly. Molecular Microbiology. 61: 33-45. PMID 16824093 DOI: 10.1111/J.1365-2958.2006.05206.X  0.709
2006 Gon S, Faulkner MJ, Beckwith J. In vivo requirement for glutaredoxins and thioredoxins in the reduction of the ribonucleotide reductases of Escherichia coli. Antioxidants & Redox Signaling. 8: 735-42. PMID 16771665 DOI: 10.1089/ars.2006.8.735  0.773
2005 Huber D, Cha MI, Debarbieux L, Planson AG, Cruz N, López G, Tasayco ML, Chaffotte A, Beckwith J. A selection for mutants that interfere with folding of Escherichia coli thioredoxin-1 in vivo. Proceedings of the National Academy of Sciences of the United States of America. 102: 18872-7. PMID 16357193 DOI: 10.1073/Pnas.0509583102  0.699
2005 Goehring NW, Beckwith J. Diverse paths to midcell: assembly of the bacterial cell division machinery. Current Biology : Cb. 15: R514-26. PMID 16005287 DOI: 10.1016/J.Cub.2005.06.038  0.709
2005 Huber D, Boyd D, Xia Y, Olma MH, Gerstein M, Beckwith J. Use of thioredoxin as a reporter to identify a subset of Escherichia coli signal sequences that promote signal recognition particle-dependent translocation Journal of Bacteriology. 187: 2983-2991. PMID 15838024 DOI: 10.1128/Jb.187.9.2983-2991.2005  0.624
2005 Goehring NW, Gueiros-Filho F, Beckwith J. Premature targeting of a cell division protein to midcell allows dissection of divisome assembly in Escherichia coli. Genes & Development. 19: 127-37. PMID 15630023 DOI: 10.1101/Gad.1253805  0.713
2005 Or E, Boyd D, Gon S, Beckwith J, Rapoport T. The bacterial ATPase SecA functions as a monomer in protein translocation Journal of Biological Chemistry. 280: 9097-9105. PMID 15618215 DOI: 10.1074/Jbc.M413947200  0.413
2004 Ortenberg R, Gon S, Porat A, Beckwith J. Interactions of glutaredoxins, ribonucleotide reductase, and components of the DNA replication system of Escherichia coli Proceedings of the National Academy of Sciences of the United States of America. 101: 7439-7444. PMID 15123823 DOI: 10.1073/pnas.0401965101  0.32
2003 Brandon LD, Goehring N, Janakiraman A, Yan AW, Wu T, Beckwith J, Goldberg MB. IcsA, a polarly localized autotransporter with an atypical signal peptide, uses the Sec apparatus for secretion, although the Sec apparatus is circumferentially distributed. Molecular Microbiology. 50: 45-60. PMID 14507362 DOI: 10.1046/J.1365-2958.2003.03674.X  0.679
2003 Schierle CF, Berkmen M, Huber D, Kumamoto C, Boyd D, Beckwith J. The DsbA signal sequence directs efficient, cotranslational export of passenger proteins to the Escherichia coli periplasm via the signal recognition particle pathway. Journal of Bacteriology. 185: 5706-13. PMID 13129941 DOI: 10.1128/Jb.185.19.5706-5713.2003  0.775
2002 Buddelmeijer N, Judson N, Boyd D, Mekalanos JJ, Beckwith J. YgbQ, a cell division protein in Escherichia coli and Vibrio cholerae, localizes in codependent fashion with FtsL to the division site. Proceedings of the National Academy of Sciences of the United States of America. 99: 6316-21. PMID 11972052 DOI: 10.1073/Pnas.092128499  0.41
2002 Chen JC, Minev M, Beckwith J. Analysis of ftsQ mutant alleles in Escherichia coli: Complementation, septal localization, and recruitment of downstream cell division proteins Journal of Bacteriology. 184: 695-705. PMID 11790739  0.322
2001 Leeds JA, Boyd D, Huber DR, Sonoda GK, Luu HT, Engelman DM, Beckwith J. Genetic selection for and molecular dynamic modeling of a protein transmembrane domain multimerization motif from a random Escherichia coli genomic library. Journal of Molecular Biology. 313: 181-95. PMID 11601855 DOI: 10.1006/Jmbi.2001.5007  0.662
2001 Ritz D, Lim J, Reynolds CM, Poole LB, Beckwith J. Conversion of a peroxiredoxin into a disulfide reductase by a triplet repeat expansion. Science (New York, N.Y.). 294: 158-60. PMID 11588261 DOI: 10.1126/Science.1063143  0.347
1998 Rietsch A, Beckwith J. The genetics of disulfide bond metabolism. Annual Review of Genetics. 32: 163-184. PMID 9928478 DOI: 10.1146/Annurev.Genet.32.1.163  0.343
1997 Rietsch A, Bessette P, Georgiou G, Beckwith J. Reduction of the periplasmic disulfide bond isomerase, DsbC, occurs by passage of electrons from cytoplasmic thioredoxin Journal of Bacteriology. 179: 6602-6608. PMID 9352906 DOI: 10.1128/Jb.179.21.6602-6608.1997  0.413
1996 Rietsch A, Belin D, Martin N, Beckwith J. An in vivo pathway for disulfide bond isomerization in Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 93: 13048-53. PMID 8917542 DOI: 10.1073/Pnas.93.23.13048  0.393
1995 Economou A, Pogliano JA, Beckwith J, Oliver DB, Wickner W. SecA membrane cycling at SecYEG is driven by distinct ATP binding and hydrolysis events and is regulated by SecD and SecF. Cell. 83: 1171-81. PMID 8548804 DOI: 10.1016/0092-8674(95)90143-4  0.612
1990 Ehrmann M, Boyd D, Beckwith J. Genetic analysis of membrane protein topology by a sandwich gene fusion approach. Proceedings of the National Academy of Sciences of the United States of America. 87: 7574-7578. PMID 2170984 DOI: 10.1073/Pnas.87.19.7574  0.649
1985 Silhavy TJ, Beckwith JR. Uses of lac fusions for the study of biological problems. Microbiological Reviews. 49: 398-418. PMID 3005818 DOI: 10.1128/Mmbr.49.4.398-418.1985  0.544
1984 Lopilato JE, Garwin JL, Emr SD, Silhavy TJ, Beckwith JR. D-ribose metabolism in Escherichia coli K-12: genetics, regulation, and transport. Journal of Bacteriology. 158: 665-73. PMID 6327616 DOI: 10.1128/Jb.158.2.665-673.1984  0.755
1983 Silhavy TJ, Beckwith J. [2] Isolation and characterization of mutants of Escherichia coli K12 affected in protein localization Methods in Enzymology. 97: 11-40. DOI: 10.1016/0076-6879(83)97115-X  0.694
1983 Beckwith J, Silhavy TJ. [1] Genetic analysis of protein export in Escherichia coli Methods in Enzymology. 97: 3-11. DOI: 10.1016/0076-6879(83)97114-8  0.688
1981 Ito K, Beckwith JR. Role of the mature protein sequence of maltose-binding protein in its secretion across the E. coli cytoplasmic membrane. Cell. 25: 143-50. PMID 7023692 DOI: 10.1016/0092-8674(81)90238-5  0.398
1980 Wu AM, Chapman AB, Platt T, Guarente LP, Beckwith J. Deletions of distal sequence affect termination of transcription at the end of the tryptophan operon in E. coli Cell. 19: 829-836. PMID 6991123 DOI: 10.1016/0092-8674(80)90073-2  0.566
1980 Shuman HA, Silhavy TJ, Beckwith JR. Labeling of proteins with beta-galactosidase by gene fusion. Identification of a cytoplasmic membrane component of the Escherichia coli maltose transport system. The Journal of Biological Chemistry. 255: 168-74. PMID 6765939  0.623
1980 Bassford P, Beckwith J, Berman M, Brickman E, Casadaban M, Guarente L, Saint-Girons I, Sarthy A, Schwartz M, Shuman H, Silhavy T. Genetic Fusions of the lac Operon: A New Approach to the Study of Biological Processes Cold Spring Harbor Monograph Archive. 7: 245-261. DOI: 10.1101/087969133.7.245  0.77
1979 Silhavy TJ, Brickman E, Bassford PJ, Casadaban MJ, Shuman HA, Schwartz V, Guarente L, Schwartz M, Beckwith JR. Structure of the malB region in Escherichia coli K12. II. Genetic map of the malE,F,G operon. Molecular & General Genetics : Mgg. 174: 249-59. PMID 384167 DOI: 10.1007/BF00267797  0.777
1979 Bassford PJ, Silhavy TJ, Beckwith JR. Use of gene fusion to study secretion of maltose-binding protein into Escherichia coli periplasm. Journal of Bacteriology. 139: 19-31. PMID 110778 DOI: 10.1128/Jb.139.1.19-31.1979  0.668
1979 Brickman E, Silhavy TJ, Bassford PJ, Shuman HA, Beckwith JR. Sites within gene lacZ of Escherichia coli for formation of active hybrid beta-galactosidase molecules. Journal of Bacteriology. 139: 13-8. PMID 110776 DOI: 10.1128/Jb.139.1.13-18.1979  0.64
1977 Silhavy TJ, Shuman HA, Beckwith J, Schwartz M. Use of gene fusions to study outer membrane protein localization in Escherichia coli Proceedings of the National Academy of Sciences of the United States of America. 74: 5411-5415. PMID 414221 DOI: 10.1073/Pnas.74.12.5411  0.665
1976 Silhavy TJ, Casadaban MJ, Shuman HA, Beckwith JR. Conversion of beta-galactosidase to a membrane-bound state by gene fusion. Proceedings of the National Academy of Sciences of the United States of America. 73: 3423-7. PMID 790385 DOI: 10.1073/Pnas.73.10.3423  0.769
1976 Mitchell DH, Reznikoff WS, Beckwith J. Genetic fusions that help define a transcription termination region in Escherichia coli Journal of Molecular Biology. 101: 441-457. PMID 772220 DOI: 10.1016/0022-2836(76)90239-4  0.567
1975 Mitchell DH, Reznikoff WS, Beckwith JR. Genetic fusions defining trp and lac operon regulatory elements. Journal of Molecular Biology. 93: 331-50. PMID 1095760 DOI: 10.1016/0022-2836(75)90281-8  0.563
1970 Miller JH, Reznikoff WS, Silverstone AE, Ippen K, Signer ER, Beckwith JR. Fusions of the lac and trp Regions of the Escherichia coli Chromosome. Journal of Bacteriology. 104: 1273-9. PMID 16559103 DOI: 10.1128/Jb.104.3.1273-1279.1970  0.76
1970 Beckwith JR. Chapter II: Lac: The Genetic System Cold Spring Harbor Monograph Archive. 1: 5-26. DOI: 10.1101/087969100.1.5  0.353
1970 Schwartz D, Beckwith JR. Research Article 16: Mutants Missing a Factor Necessary for the Expression of Catabolite-Sensitive Operons in E. coli Cold Spring Harbor Monograph Archive. 1: 417-424. DOI: 10.1101/087969100.1.417  0.33
1970 Eron L, Beckwith JR, Jacob F. Research Article 11: Deletion of Translational Start Signals in the lac Operon of E. coli Cold Spring Harbor Monograph Archive. 1: 353-358. DOI: 10.1101/087969100.1.353  0.357
1969 Gottesman S, Beckwith JR. Directed transposition of the arabinose operon: a technique for the isolation of specialized transducing bacteriophages for any Escherichia coli gene. Journal of Molecular Biology. 44: 117-27. PMID 4897798 DOI: 10.1016/0022-2836(69)90408-2  0.581
1969 Reznikoff WS, Beckwith JR. Genetic evidence that the operator locus is distinct from the the z gene in the lac operon of Escherichia coli. Journal of Molecular Biology. 43: 215-8. PMID 4897792 DOI: 10.1016/0022-2836(69)90090-4  0.578
1969 Reznikoff WS, Miller JH, Scaife JG, Beckwith JR. A mechanism for repressor action. Journal of Molecular Biology. 43: 201-13. PMID 4897791 DOI: 10.1016/0022-2836(69)90089-8  0.681
1969 Silverstone AE, Magasanik B, Reznikoff WS, Miller JH, Beckwith JR. Catabolite sensitive site of the lac operon. Nature. 221: 1012-4. PMID 4886742 DOI: 10.1038/2211012B0  0.655
1968 Miller JH, Ippen K, Scaife JG, Beckwith JR. The promoter-operator region of the lac operon of Escherichia coli. Journal of Molecular Biology. 38: 413-20. PMID 4887877 DOI: 10.1016/0022-2836(68)90395-1  0.508
1968 Ippen K, Miller JH, Scaife J, Beckwith J. New controlling element in the Lac operon of E. coli. Nature. 217: 825-7. PMID 4867974 DOI: 10.1038/217825A0  0.55
1968 Dubnau D, Kanan E, Mindich L, Novick R, Smith I, Darnell J, Hurwitz J, Rubin H, Abbott J, Holtzman E, Zipser D, Beckwith J, Gorini L, Sager R, Duerksen J, et al. A Moral Duty Bioscience. 18: 367-368. DOI: 10.2307/1294112  0.629
1967 Beckwith JR. Regulation of the lac operon. Recent studies on the regulation of lactose metabolism in Escherichia coli support the operon model. Science (New York, N.Y.). 156: 597-604. PMID 5337175 DOI: 10.1126/Science.156.3775.597  0.301
1966 Fox CF, Beckwith JR, Epstein W, Signer ER. Transposition of the lac region of Escherichia coli. II. On the role of thiogalactoside transacetylase in lactose metabolism. Journal of Molecular Biology. 19: 576-9. PMID 5338859 DOI: 10.1016/S0022-2836(66)80025-6  0.614
1966 Beckwith JR, Signer ER. Transposition of the lac region of Escherichia coli. I. Inversion of the lac operon and transduction of lac by phi80. Journal of Molecular Biology. 19: 254-65. PMID 5338856 DOI: 10.1016/S0022-2836(66)80003-7  0.642
1966 Beckwith JR, Signer ER, Epstein W. Transposition of the Lac region of E. coli. Cold Spring Harbor Symposia On Quantitative Biology. 31: 393-401. PMID 4866389 DOI: 10.1101/Sqb.1966.031.01.051  0.619
1966 Signer ER, Beckwith JR. Transposition of the lac region of Escherichia coli. III. The mechanism of attachment of bacteriophage φ80 to the bacterial chromosome Journal of Molecular Biology. 22: 33-51. DOI: 10.1016/0022-2836(66)90178-1  0.63
1965 Newton WA, Beckwith JR, Zipser D, Brenner S. Nonsense mutants and polarity in the lac operon of Escherichia coli. Journal of Molecular Biology. 14: 290-6. PMID 5327654 DOI: 10.1016/S0022-2836(65)80250-9  0.54
1965 Signer ER, Beckwith JR, Brenner S. Mapping of suppressor loci in Escherichia coli. Journal of Molecular Biology. 14: 153-66. PMID 5327649 DOI: 10.1016/S0022-2836(65)80237-6  0.672
1964 TAYLOR AL, BECKWITH JR, PARDEE AB, AUSTRIAN R, JACOB F. THE CHROMOSOMAL LOCATION OF THE STRUCTURAL GENE FOR OROTIDYLIC ACID PYROPHOSPHORYLASE IN ESCHERICHIA COLI. Journal of Molecular Biology. 8: 771. PMID 14187401 DOI: 10.1016/S0022-2836(64)80124-8  0.582
1964 BECKWITH JR. A DELETION ANALYSIS OF THE LAC OPERATOR REGION IN ESCHERICHIA COLI. Journal of Molecular Biology. 8: 427-30. PMID 14168696 DOI: 10.1016/S0022-2836(64)80206-0  0.312
1963 BECKWITH JR, HAGER LP. BIOLOGICAL CHLORINATION. VIII. LATE INTERMEDIATES IN THE BIOSYNTHESIS OF CALDARIOMYCIN. The Journal of Biological Chemistry. 238: 3091-4. PMID 14081930  0.475
1963 BECKWITH JR, CLARK R, HAGER LP. BIOLOGICAL CHLORINATION. VII. STUDIES ON THE BIOSYNTHESIS OF CALDARIOMYCIN. The Journal of Biological Chemistry. 238: 3086-90. PMID 14081929  0.469
1962 PARDEE AB, BECKWITH JR. Genetic determination of constitutive enzyme levels. Biochimica Et Biophysica Acta. 60: 452-4. PMID 14483809 DOI: 10.1016/0006-3002(62)90435-3  0.401
1962 BECKWITH JR, PARDEE AB, AUSTRIAN R, JACOB F. Coordination of the synthesis of the enzymes in the pyrimidine pathway of E. coli. Journal of Molecular Biology. 5: 618-34. PMID 13970180 DOI: 10.1016/S0022-2836(62)80090-4  0.579
1961 Beckwith JR, Hager LP. Synthesis of D,L-caldariomycin Journal of Organic Chemistry. 26: 5206-5208. DOI: 10.1021/Jo01070A515  0.428
1959 SHAW PD, BECKWITH JR, HAGER LP. Biological chlorination. II. The biosynthesis of 5-chlorolevulinic acid. The Journal of Biological Chemistry. 234: 2560-4. PMID 14445651  0.455
Show low-probability matches.