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Michael W. Klymkowsky - Publications

Affiliations: 
Molecular Cellular and Developmental Biology University of Colorado, Boulder, Boulder, CO, United States 
Area:
membrane-bound bacteriophage, electric fish & synaptic receptors, intermediate filaments, adhesion, gene regulation, germ layer specification and interactions
Website:
http://spot.colorado.edu/~klym/research.htm

55 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Klymkowsky MW. Filaments and phenotypes: cellular roles and orphan effects associated with mutations in cytoplasmic intermediate filament proteins. F1000research. 8. PMID 31602295 DOI: 10.12688/F1000Research.19950.1  0.329
2017 Lai MB, Zhang C, Shi J, Johnson V, Khandan L, McVey J, Klymkowsky MW, Chen Z, Junge HJ. TSPAN12 Is a Norrin Co-receptor that Amplifies Frizzled4 Ligand Selectivity and Signaling. Cell Reports. 19: 2809-2822. PMID 28658627 DOI: 10.1016/J.Celrep.2017.06.004  0.316
2017 McClure-Begley TD, Klymkowsky MW. Nuclear roles for cilia-associated proteins. Cilia. 6: 8. PMID 28560031 DOI: 10.1186/S13630-017-0052-X  0.322
2016 Zhao Y, Shi J, Winey M, Klymkowsky MW. Identifying domains of EFHC1 involved in ciliary localization, ciliogenesis, and the regulation of Wnt signaling. Developmental Biology. PMID 26783883 DOI: 10.1016/J.Ydbio.2016.01.004  0.412
2015 Shi J, Zhao Y, Vonderfecht T, Winey M, Klymkowsky MW. Centrin-2 (Cetn2) mediated regulation of FGF/FGFR gene expression in Xenopus. Scientific Reports. 5: 10283. PMID 26014913 DOI: 10.1038/Srep10283  0.335
2015 Square T, Romášek M, Jandzik D, Cattell MV, Klymkowsky M, Medeiros DM. CRISPR/Cas9-mediated mutagenesis in the sea lamprey petromyzon marinus: A powerful tool for understanding ancestral gene functions in vertebrates Development (Cambridge). 142: 4180-4187. DOI: 10.1242/Dev.125609  0.305
2014 Shi J, Zhao Y, Galati D, Winey M, Klymkowsky MW. Chibby functions in Xenopus ciliary assembly, embryonic development, and the regulation of gene expression. Developmental Biology. 395: 287-98. PMID 25220153 DOI: 10.1016/J.Ydbio.2014.09.008  0.398
2012 Shi J, Zhang H, Dowell RD, Klymkowsky MW. sizzled function and secreted factor network dynamics. Biology Open. 1: 286-94. PMID 23213419 DOI: 10.1242/Bio.2012019  0.377
2012 Cattell MV, Garnett AT, Klymkowsky MW, Medeiros DM. A maternally established SoxB1/SoxF axis is a conserved feature of chordate germ layer patterning. Evolution & Development. 14: 104-15. PMID 23016978 DOI: 10.1111/J.1525-142X.2011.00525.X  0.309
2011 Shi J, Severson C, Yang J, Wedlich D, Klymkowsky MW. Snail2 controls mesodermal BMP/Wnt induction of neural crest. Development (Cambridge, England). 138: 3135-45. PMID 21715424 DOI: 10.1242/Dev.064394  0.348
2011 Klymkowsky MW. Mitochondrial activity, embryogenesis, and the dialogue between the big and little brains of the cell. Mitochondrion. 11: 814-9. PMID 21134489 DOI: 10.1016/J.Mito.2010.11.002  0.319
2010 Hikasa H, Ezan J, Itoh K, Li X, Klymkowsky MW, Sokol SY. Regulation of TCF3 by Wnt-dependent phosphorylation during vertebrate axis specification. Developmental Cell. 19: 521-32. PMID 20951344 DOI: 10.1016/J.Devcel.2010.09.005  0.383
2009 Zhang C, Klymkowsky MW. Unexpected functional redundancy between Twist and Slug (Snail2) and their feedback regulation of NF-kappaB via Nodal and Cerberus. Developmental Biology. 331: 340-9. PMID 19389392 DOI: 10.1016/J.Ydbio.2009.04.016  0.333
2007 Zhang C, Klymkowsky MW. The Sox axis, Nodal signaling, and germ layer specification. Differentiation; Research in Biological Diversity. 75: 536-45. PMID 17608734 DOI: 10.1111/J.1432-0436.2007.00190.X  0.372
2006 Zhang C, Carl TF, Trudeau ED, Simmet T, Klymkowsky MW. An NF-kappaB and slug regulatory loop active in early vertebrate mesoderm. Plos One. 1: e106. PMID 17205110 DOI: 10.1371/Journal.Pone.0000106  0.336
2005 Zhang C, Basta T, Klymkowsky MW. SOX7 and SOX18 are essential for cardiogenesis in Xenopus. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 234: 878-91. PMID 16193513 DOI: 10.1002/Dvdy.20565  0.412
2005 Klymkowsky MW. beta-catenin and its regulatory network. Human Pathology. 36: 225-7. PMID 15791565 DOI: 10.1016/J.Humpath.2005.02.002  0.329
2005 Zhang C, Basta T, Fawcett SR, Klymkowsky MW. SOX7 is an immediate-early target of VegT and regulates Nodal-related gene expression in Xenopus. Developmental Biology. 278: 526-41. PMID 15680368 DOI: 10.1016/J.Ydbio.2004.11.008  0.345
2004 Zhang C, Basta T, Hernandez-Lagunas L, Simpson P, Stemple DL, Artinger KB, Klymkowsky MW. Repression of nodal expression by maternal B1-type SOXs regulates germ layer formation in Xenopus and zebrafish. Developmental Biology. 273: 23-37. PMID 15302595 DOI: 10.1016/J.Ydbio.2004.05.019  0.379
2004 Fawcett SR, Klymkowsky MW. Embryonic expression of Xenopus laevis SOX7. Gene Expression Patterns : Gep. 4: 29-33. PMID 14678825 DOI: 10.1016/J.Modgep.2003.08.003  0.365
2003 Zhang C, Basta T, Jensen ED, Klymkowsky MW. The beta-catenin/VegT-regulated early zygotic gene Xnr5 is a direct target of SOX3 regulation. Development (Cambridge, England). 130: 5609-24. PMID 14522872 DOI: 10.1242/Dev.00798  0.4
2003 Haubold K, Herrmann H, Langer SJ, Evans RM, Leinwand LA, Klymkowsky MW. Acute effects of desmin mutations on cytoskeletal and cellular integrity in cardiac myocytes. Cell Motility and the Cytoskeleton. 54: 105-21. PMID 12529857 DOI: 10.1002/Cm.10090  0.311
2001 Hanken J, Carl TF, Richardson MK, Olsson L, Schlosser G, Osabutey CK, Klymkowsky MW. Limb development in a "nonmodel" vertebrate, the direct-developing frog Eleutherodactylus coqui. The Journal of Experimental Zoology. 291: 375-88. PMID 11754016 DOI: 10.1002/Jez.1136  0.308
2001 St Amand AL, Klymkowsky MW. Cadherins and catenins, Wnts and SOXs: embryonic patterning in Xenopus. International Review of Cytology. 203: 291-355. PMID 11131519 DOI: 10.1016/S0074-7696(01)03010-8  0.443
2000 Williams BO, Barish GD, Klymkowsky MW, Varmus HE. A comparative evaluation of beta-catenin and plakoglobin signaling activity. Oncogene. 19: 5720-8. PMID 11126358 DOI: 10.1038/Sj.Onc.1203921  0.401
1999 Zorn AM, Barish GD, Williams BO, Lavender P, Klymkowsky MW, Varmus HE. Regulation of Wnt signaling by Sox proteins: XSox17 alpha/beta and XSox3 physically interact with beta-catenin. Molecular Cell. 4: 487-98. PMID 10549281 DOI: 10.1016/S1097-2765(00)80200-2  0.406
1999 Klymkowsky MW, Williams BO, Barish GD, Varmus HE, Vourgourakis YE. Membrane-anchored plakoglobins have multiple mechanisms of action in Wnt signaling. Molecular Biology of the Cell. 10: 3151-69. PMID 10512857 DOI: 10.1091/Mbc.10.10.3151  0.595
1999 Carl TF, Dufton C, Hanken J, Klymkowsky MW. Inhibition of neural crest migration in Xenopus using antisense slug RNA. Developmental Biology. 213: 101-15. PMID 10452849 DOI: 10.1006/Dbio.1999.9320  0.315
1999 Klymkowsky MW. Plakophilin, armadillo repeats, and nuclear localization. Microscopy Research and Technique. 45: 43-54. PMID 10206153 DOI: 10.1002/(Sici)1097-0029(19990401)45:1<43::Aid-Jemt4>3.0.Co;2-C  0.329
1997 Merriam JM, Rubenstein AB, Klymkowsky MW. Cytoplasmically anchored plakoglobin induces a WNT-like phenotype in Xenopus. Developmental Biology. 185: 67-81. PMID 9169051 DOI: 10.1006/Dbio.1997.8550  0.415
1997 Rubenstein A, Merriam J, Klymkowsky MW. Localizing the adhesive and signaling functions of plakoglobin. Developmental Genetics. 20: 91-102. PMID 9144920 DOI: 10.1002/(Sici)1520-6408(1997)20:2<91::Aid-Dvg2>3.0.Co;2-3  0.372
1996 Bachant JB, Klymkowsky MW. A nontetrameric species is the major soluble form of keratin in Xenopus oocytes and rabbit reticulocyte lysates. The Journal of Cell Biology. 132: 153-65. PMID 8567720 DOI: 10.1083/Jcb.132.1.153  0.696
1995 Klymkowsky MW. Intermediate filament organization, reorganization, and function in the clawed frog Xenopus. Current Topics in Developmental Biology. 31: 455-86. PMID 8746673 DOI: 10.1016/S0070-2153(08)60236-7  0.361
1995 Karnovsky A, Klymkowsky MW. Anterior axis duplication in Xenopus induced by the over-expression of the cadherin-binding protein plakoglobin. Proceedings of the National Academy of Sciences of the United States of America. 92: 4522-6. PMID 7753837 DOI: 10.1073/Pnas.92.10.4522  0.384
1995 Klymkowsky MW. Intermediate filaments: new proteins, some answers, more questions. Current Opinion in Cell Biology. 7: 46-54. PMID 7538773 DOI: 10.1016/0955-0674(95)80044-1  0.315
1995 Klymkowsky MW, Evans RM. Chapter 7 Intermediate filaments: A medical overview Principles of Medical Biology. 2: 147-188. DOI: 10.1016/S1569-2582(06)80040-1  0.301
1994 Seufert DW, Hanken J, Klymkowsky MW. Type II collagen distribution during cranial development in Xenopus laevis. Anatomy and Embryology. 189: 81-9. PMID 8192239 DOI: 10.1007/Bf00193131  0.303
1994 Doedens J, Maynell LA, Klymkowsky MW, Kirkegaard K. Secretory pathway function, but not cytoskeletal integrity, is required in poliovirus infection. Archives of Virology. Supplementum. 9: 159-72. PMID 8032247 DOI: 10.1007/978-3-7091-9326-6_16  0.318
1994 Klymkowsky MW, Karnovsky A. Morphogenesis and the cytoskeleton: studies of the Xenopus embryo. Developmental Biology. 165: 372-84. PMID 7525386 DOI: 10.1006/Dbio.1994.1260  0.335
1994 Cary RB, Klymkowsky MW. Differential organization of desmin and vimentin in muscle is due to differences in their head domains. The Journal of Cell Biology. 126: 445-56. PMID 7518466 DOI: 10.1083/Jcb.126.2.445  0.335
1992 Dent JA, Cary RB, Bachant JB, Domingo A, Klymkowsky MW. Host cell factors controlling vimentin organization in the Xenopus oocyte. The Journal of Cell Biology. 119: 855-66. PMID 1429840 DOI: 10.1083/Jcb.119.4.855  0.708
1992 Klymkowsky MW, Shook DR, Maynell LA. Evidence that the deep keratin filament systems of the Xenopus embryo act to ensure normal gastrulation. Proceedings of the National Academy of Sciences of the United States of America. 89: 8736-40. PMID 1382297 DOI: 10.1073/Pnas.89.18.8736  0.311
1991 Klymkowsky MW, Maynell LA, Nislow C. Cytokeratin phosphorylation, cytokeratin filament severing and the solubilization of the maternal mRNA Vg1. The Journal of Cell Biology. 114: 787-97. PMID 1714462 DOI: 10.1083/Jcb.114.4.787  0.313
1989 Marazzi G, Bard F, Klymkowsky MW, Rubin LL. Microinjection of a monoclonal antibody against a 37-kD protein (tropomyosin 2) prevents the formation of new acetylcholine receptor clusters. The Journal of Cell Biology. 109: 2337-44. PMID 2808531 DOI: 10.1083/Jcb.109.5.2337  0.44
1989 Klymkowsky MW, Bachant JB, Domingo A. Functions of intermediate filaments. Cell Motility and the Cytoskeleton. 14: 309-31. PMID 2684432 DOI: 10.1002/Cm.970140302  0.709
1989 Chu DT, Klymkowsky MW. The appearance of acetylated alpha-tubulin during early development and cellular differentiation in Xenopus. Developmental Biology. 136: 104-17. PMID 2680681 DOI: 10.1016/0012-1606(89)90134-6  0.305
1989 Klymkowsky MW, Maynell LA. MPF-induced breakdown of cytokeratin filament organization in the maturing Xenopus oocyte depends upon the translation of maternal mRNAs. Developmental Biology. 134: 479-85. PMID 2472987 DOI: 10.1016/0012-1606(89)90121-8  0.346
1985 Rubin LL, Chalfin NA, Adamo A, Klymkowsky MW. Cellular and secreted forms of acetylcholinesterase in mouse muscle cultures. Journal of Neurochemistry. 45: 1932-40. PMID 4056799 DOI: 10.1111/J.1471-4159.1985.Tb10553.X  0.444
1985 Klymkowsky MW, Plummer DJ. Giant axonal neuropathy: a conditional mutation affecting cytoskeletal organization. The Journal of Cell Biology. 100: 245-50. PMID 3880753 DOI: 10.1083/Jcb.100.1.245  0.303
1983 Klymkowsky MW, Miller RH, Lane EB. Morphology, behavior, and interaction of cultured epithelial cells after the antibody-induced disruption of keratin filament organization. The Journal of Cell Biology. 96: 494-509. PMID 6187752 DOI: 10.1083/Jcb.96.2.494  0.329
1982 Kistler J, Stroud RM, Klymkowsky MW, Lalancette RA, Fairclough RH. Structure and function of an acetylcholine receptor. Biophysical Journal. 37: 371-83. PMID 7055628 DOI: 10.1016/S0006-3495(82)84685-7  0.448
1981 Klymkowsky MW. Intermediate filaments in 3T3 cells collapse after intracellular injection of a monoclonal anti-intermediate filament antibody. Nature. 291: 249-51. PMID 6785655 DOI: 10.1038/291249A0  0.317
1980 Klymkowsky MW, Heuser JE, Stroud RM. Protease effects on the structure of acetylcholine receptor membranes from Torpedo californica. The Journal of Cell Biology. 85: 823-38. PMID 6993498 DOI: 10.1083/Jcb.85.3.823  0.462
1979 Klymkowsky MW, Stroud RM. Immunospecific identification and three-dimensional structure of a membrane-bound acetylcholine receptor from Torpedo californica. Journal of Molecular Biology. 128: 319-34. PMID 439138 DOI: 10.1016/0022-2836(79)90091-3  0.451
1977 Ross MJ, Klymkowsky MW, Agard DA, Stroud RM. Structural studies of a membrane-bound acetylcholine receptor from Torpedo californica. Journal of Molecular Biology. 116: 635-59. PMID 563472 DOI: 10.1016/0022-2836(77)90264-9  0.563
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