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Won-Sik Shim, Ph.D. - Publications

Affiliations: 
Pharmacy Gacheon University 
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27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Cha J, Ryu J, Rawal D, Lee WJ, Shim WS. Antipruritic effect of ursolic acid through MRGPRX2/MrgprB2-dependent inhibition of mast cell degranulation and reduced TSLP production. European Journal of Pharmacology. 176896. PMID 39147012 DOI: 10.1016/j.ejphar.2024.176896  0.337
2024 Kim H, Shim WS, Oh U. Anoctamin 1, a multi-modal player in pain and itch. Cell Calcium. 123: 102924. PMID 38964236 DOI: 10.1016/j.ceca.2024.102924  0.572
2024 Adhikari N, Lee WJ, Park S, Kim S, Shim WS. A phytosphingosine derivative mYG-II-6 inhibits histamine-mediated TRPV1 activation and MRGPRX2-dependent mast cell degranulation. International Immunopharmacology. 133: 112113. PMID 38657498 DOI: 10.1016/j.intimp.2024.112113  0.672
2022 Adhikari N, Shim WS. Caffeic acid phenethyl ester inhibits pseudo-allergic reactions via inhibition of MRGPRX2/MrgprB2-dependent mast cell degranulation. Archives of Pharmacal Research. PMID 36183260 DOI: 10.1007/s12272-022-01405-2  0.688
2022 Kim H, Kim H, Cho H, Lee B, Lu HJ, Kim K, Chung S, Shim WS, Shin YK, Dong X, Wood JN, Oh U. Anoctamin 1/TMEM16A in pruritoceptors is essential for Mas-related G protein receptor-dependent itch. Pain. PMID 35135993 DOI: 10.1097/j.pain.0000000000002611  0.589
2020 Choi DS, Ji Y, Jang Y, Lee WJ, Shim WS. Crotamiton, an Anti-Scabies Agent, Suppresses Histamine- and Chloroquine-Induced Itch Pathways in Sensory Neurons and Alleviates Scratching in Mice. Biomolecules & Therapeutics. PMID 32536619 DOI: 10.4062/Biomolther.2020.063  0.433
2019 Sanjel B, Maeng HJ, Shim WS. BAM8-22 and its receptor MRGPRX1 may attribute to cholestatic pruritus. Scientific Reports. 9: 10888. PMID 31350433 DOI: 10.1038/S41598-019-47267-5  0.38
2019 Kim BH, Lee WJ, Sanjel B, Cho K, Son YK, Park HY, Kim SY, Shim WS. Extracts of the leaves of Pyrus ussuriensis Maxim. Alleviate itch sensation via TSLP-dependent manner in mouse models of atopic dermatitis. Physiology & Behavior. 112624. PMID 31325512 DOI: 10.1016/J.Physbeh.2019.112624  0.378
2018 Lee WJ, Kim YS, Shim WS. Korean Red Ginseng extract and ginsenoside Rg3 have anti-pruritic effects on chloroquine-induced itch by inhibition of MrgprA3/TRPA1-mediated pathway. Journal of Ginseng Research. 42: 470-475. PMID 30337807 DOI: 10.1016/J.Jgr.2017.05.004  0.373
2018 Ji Y, Jang Y, Lee WJ, Yang YD, Shim WS. Different perception levels of histamine-induced itch sensation in young adult mice. Physiology & Behavior. PMID 29432788 DOI: 10.1016/J.Physbeh.2018.02.015  0.513
2018 Jang Y, Lee B, Kim EK, Shim WS, Yang YD, Kim SM. Involuntary swimming exercise in pregnant rats disturbs ERK1/2 signaling in embryonic neurons through increased cortisol in the amniotic fluid. Biochemical and Biophysical Research Communications. 495: 1208-1213. PMID 29183725 DOI: 10.1016/J.Bbrc.2017.11.153  0.489
2017 Afzal R, Shim WS. Glucosylsphingosine Activates Serotonin Receptor 2a and 2b: Implication of a Novel Itch Signaling Pathway. Biomolecules & Therapeutics. PMID 28208011 DOI: 10.4062/Biomolther.2016.207  0.397
2016 Venkatesan R, Shim WS, Yeo EJ, Kim SY. Lactucopicrin potentiates neuritogenesis and neurotrophic effects by regulating Ca(2+)/CaMKII/ATF1 signaling pathway. Journal of Ethnopharmacology. PMID 28011163 DOI: 10.1016/J.Jep.2016.12.035  0.307
2015 Hwang E, Lee TH, Lee WJ, Shim WS, Yeo EJ, Kim S, Kim SY. A novel synthetic Piper amide derivative NED-180 inhibits hyperpigmentation by activating the PI3K and ERK pathways and by regulating Ca(2+) influx via TRPM1 channels. Pigment Cell & Melanoma Research. PMID 26459162 DOI: 10.1111/Pcmr.12430  0.407
2015 Jang Y, Lee WJ, Hong GS, Shim WS. Red ginseng extract blocks histamine-dependent itch by inhibition of H1R/TRPV1 pathway in sensory neurons. Journal of Ginseng Research. 39: 257-64. PMID 26199558 DOI: 10.1016/J.Jgr.2015.01.004  0.447
2015 Pradhananga S, Shim WS. Caffeic acid exhibits anti-pruritic effects by inhibition of multiple itch transmission pathways in mice. European Journal of Pharmacology. 762: 313-21. PMID 26057691 DOI: 10.1016/J.Ejphar.2015.06.006  0.406
2015 Sundaramoorthy P, Sim JJ, Jang YS, Mishra SK, Jeong KY, Mander P, Chul OB, Shim WS, Oh SH, Nam KY, Kim HM. Modulation of intracellular calcium levels by calcium lactate affects colon cancer cell motility through calcium-dependent calpain. Plos One. 10: e0116984. PMID 25629974 DOI: 10.1371/Journal.Pone.0116984  0.342
2013 Kim KS, Shim WS, dela Peña IC, Seo EK, Kim WY, Jin HE, Kim DD, Chung SJ, Cheong JH, Shim CK. Smooth muscle relaxation activity of an aqueous extract of dried immature fruit of Poncirus trifoliata (PF-W) on an isolated strip of rat ileum. Natural Product Communications. 8: 1143-8. PMID 24079189 DOI: 10.1177/1934578X1300800829  0.308
2013 Jang Y, Kim SW, Oh J, Hong GS, Seo EK, Oh U, Shim WS. Ghrelin receptor is activated by naringin and naringenin, constituents of a prokinetic agent Poncirus fructus. Journal of Ethnopharmacology. 148: 459-65. PMID 23639361 DOI: 10.1016/J.Jep.2013.04.039  0.58
2012 Kwak EY, Choi MK, Yang SG, Shim CK, Shim WS. Investigation into the Efficacy of Val-SN-38, a Valine-Ester Prodrug of the Anti-Cancer Agent SN-38. Biomolecules & Therapeutics. 20: 326-31. PMID 24130931 DOI: 10.4062/Biomolther.2012.20.3.326  0.313
2010 Shim WS, Back H, Jung SW, Kim JW, Jang Y, Lee B, Seo EK, Oh U, Shim CK. An aqueous extract of Poncirus fructus activates the prokinetic activity of 5-HT receptor subtype 4 without hERG interaction. Journal of Ethnopharmacology. 132: 328-33. PMID 20736054 DOI: 10.1016/J.Jep.2010.08.042  0.604
2008 Yang YD, Cho H, Koo JY, Tak MH, Cho Y, Shim WS, Park SP, Lee J, Lee B, Kim BM, Raouf R, Shin YK, Oh U. TMEM16A confers receptor-activated calcium-dependent chloride conductance. Nature. 455: 1210-5. PMID 18724360 DOI: 10.1038/Nature07313  0.658
2008 Shim WS, Oh U. Histamine-induced itch and its relationship with pain. Molecular Pain. 4: 29. PMID 18667087 DOI: 10.1186/1744-8069-4-29  0.571
2007 Shim WS, Tak MH, Lee MH, Kim M, Kim M, Koo JY, Lee CH, Kim M, Oh U. TRPV1 mediates histamine-induced itching via the activation of phospholipase A2 and 12-lipoxygenase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 2331-7. PMID 17329430 DOI: 10.1523/Jneurosci.4643-06.2007  0.623
2006 Kim S, Kang C, Shin CY, Hwang SW, Yang YD, Shim WS, Park MY, Kim E, Kim M, Kim BM, Cho H, Shin Y, Oh U. TRPV1 recapitulates native capsaicin receptor in sensory neurons in association with Fas-associated factor 1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 2403-12. PMID 16510717 DOI: 10.1523/Jneurosci.4691-05.2006  0.679
2004 Kim BM, Lee SH, Shim WS, Oh U. Histamine-induced Ca(2+) influx via the PLA(2)/lipoxygenase/TRPV1 pathway in rat sensory neurons. Neuroscience Letters. 361: 159-62. PMID 15135918 DOI: 10.1016/J.Neulet.2004.01.019  0.594
2003 Cho H, Kim MS, Shim WS, Yang YD, Koo J, Oh U. Calcium-activated cationic channel in rat sensory neurons. The European Journal of Neuroscience. 17: 2630-8. PMID 12823470 DOI: 10.1046/J.1460-9568.2003.02706.X  0.733
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