Ian F. Harrison - Publications

Affiliations: 
Imperial College, London, London, England, United Kingdom 
Area:
Parkinson's Disease

25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Ohene Y, Harrison IF, Evans PG, Thomas DL, Lythgoe MF, Wells JA. Increased blood-brain barrier permeability to water in the aging brain detected using noninvasive multi-TE ASL MRI. Magnetic Resonance in Medicine. PMID 32910547 DOI: 10.1002/Mrm.28496  0.312
2020 Migdalska-Richards A, Wegrzynowicz M, Harrison IF, Verona G, Bellotti V, Spillantini MG, Schapira AHV. L444P Gba1 mutation increases formation and spread of α-synuclein deposits in mice injected with mouse α-synuclein pre-formed fibrils. Plos One. 15: e0238075. PMID 32833982 DOI: 10.1371/Journal.Pone.0238075  0.3
2020 Harrison IF, Ismail O, Machhada A, Colgan N, Ohene Y, Nahavandi P, Ahmed Z, Fisher A, Meftah S, Murray TK, Ottersen OP, Nagelhus EA, O'Neill MJ, Wells JA, Lythgoe MF. Impaired glymphatic function and clearance of tau in an Alzheimer's disease model. Brain : a Journal of Neurology. PMID 32705145 DOI: 10.1093/Brain/Awaa179  0.395
2019 Ismail O, Harrison IF, Wells JA, Nahavandi P, Ohene Y, Evans P, Ahmed Z, Sung K, Murray TK, O'Neill MJ, Wiseman FK, Fisher E, Lythgoe MF. Ic-P-019: Dynamic Contrast-Enhanced Mri To Assess Glymphatic Function In The Nl-F Mouse Model Of Alzheimer'S Disease Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.2477  0.329
2018 Harrison IF, Powell NM, Dexter DT. The Histone Deacetylase Inhibitor Nicotinamide Exacerbates Neurodegeneration in the Lactacystin Rat Model of Parkinson's Disease. Journal of Neurochemistry. PMID 30269333 DOI: 10.1111/Jnc.14599  0.687
2018 Hadjihambi A, Harrison IF, Costas-Rodríguez M, Vanhaecke F, Arias N, Gallego-Durán R, Mastitskaya S, Hosford PS, Olde Damink SWM, Davies N, Habtesion A, Lythgoe MF, Gourine AV, Jalan R. Impaired brain glymphatic flow in experimental hepatic encephalopathy. Journal of Hepatology. PMID 30201461 DOI: 10.1016/J.Jhep.2018.08.021  0.338
2018 Harrison IF, Siow B, Akilo AB, Evans PG, Ismail O, Ohene Y, Nahavandi P, Thomas DL, Lythgoe MF, Wells JA. Non-invasive imaging of CSF-mediated brain clearance pathways via assessment of perivascular fluid movement with DTI MRI. Elife. 7. PMID 30063207 DOI: 10.7554/Elife.34028  0.359
2018 Ismail O, Harrison IF, Wells JA, Nahavandi P, Ohene Y, Ahmed Z, Fisher A, Murray TK, O'Neill MJ, Wiseman FK, Fisher E, Lythgoe MF. Ic-P-052: Glymphatic Function During Early Stage Amyloid Pathology: Dynamic Contrast-Enhanced Mri In The J20 Mouse Model Of Alzheimer'S Disease Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.2117  0.34
2017 Harrison IF, Smith AD, Dexter DT. Pathological histone acetylation in Parkinson's disease: Neuroprotection and inhibition of microglial activation through SIRT 2 inhibition. Neuroscience Letters. 666: 48-57. PMID 29273397 DOI: 10.1016/J.Neulet.2017.12.037  0.673
2017 Colgan N, Ganeshan B, Harrison IF, Ismail O, Holmes HE, Wells JA, Powell NM, O'Callaghan JM, O'Neill MJ, Murray TK, Ahmed Z, Collins EC, Johnson RA, Groves A, Lythgoe MF. In Vivo Imaging of Tau Pathology Using Magnetic Resonance Imaging Textural Analysis. Frontiers in Neuroscience. 11: 599. PMID 29163005 DOI: 10.3389/Fnins.2017.00599  0.317
2017 O'Callaghan J, Holmes H, Powell N, Wells JA, Ismail O, Harrison IF, Siow B, Johnson R, Ahmed Z, Fisher A, Meftah S, O'Neill MJ, Murray TK, Collins EC, Shmueli K, et al. Tissue magnetic susceptibility mapping as a marker of tau pathology in Alzheimer's disease. Neuroimage. 159: 334-345. PMID 28797738 DOI: 10.1016/J.Neuroimage.2017.08.003  0.352
2017 Holmes HE, Powell NM, Ma D, Ismail O, Harrison IF, Wells JA, Colgan N, O'Callaghan JM, Johnson RA, Murray TK, Ahmed Z, Heggenes M, Fisher A, Cardoso MJ, Modat M, et al. Comparison of In Vivo and Ex Vivo MRI for the Detection of Structural Abnormalities in a Mouse Model of Tauopathy. Frontiers in Neuroinformatics. 11: 20. PMID 28408879 DOI: 10.3389/Fninf.2017.00020  0.391
2017 Hadjihambi A, Harrison I, Rizzo G, Macnaughtan J, Beaton N, Davies N, Habtesion A, Jalan R. Brain glymphatic clearance is impaired in a rat model of cirrhosis Journal of Hepatology. 66. DOI: 10.1016/S0168-8278(17)30560-3  0.335
2017 Hadjihambi A, Harrison I, Rizzo G, Macnaughtan J, Beaton N, Davies N, Habtetion A, Jalan R. Brain Glymphatic Clearance is Impaired in a Rat Model of Cirrhosis Journal of Clinical and Experimental Hepatology. 7. DOI: 10.1016/J.Jceh.2017.01.069  0.335
2016 Holmes HE, Colgan N, Ismail O, Ma D, Powell NM, O'Callaghan JM, Harrison IF, Johnson RA, Murray TK, Ahmed Z, Heggenes M, Fisher A, Cardoso MJ, Modat M, Walker-Samuel S, et al. Imaging the accumulation and suppression of tau pathology using multiparametric MRI. Neurobiology of Aging. 39: 184-94. PMID 26923415 DOI: 10.1016/J.Neurobiolaging.2015.12.001  0.386
2015 Harrison IF, Anis HK, Dexter DT. Associated Degeneration of Ventral Tegmental Area Dopaminergic Neurons in the Rat Nigrostriatal Lactacystin Model of Parkinsonism and their Neuroprotection by Valproate. Neuroscience Letters. PMID 26742637 DOI: 10.1016/J.Neulet.2015.12.052  0.648
2015 Colgan N, Siow B, O'Callaghan JM, Harrison IF, Wells JA, Holmes HE, Ismail O, Richardson S, Alexander DC, Collins EC, Fisher EM, Johnson R, Schwarz AJ, Ahmed Z, O'Neill MJ, et al. Application of neurite orientation dispersion and density imaging (NODDI) to a tau pathology model of Alzheimer's disease. Neuroimage. PMID 26505297 DOI: 10.1016/J.Neuroimage.2015.10.043  0.366
2015 Harrison IF, Crum WR, Vernon AC, Dexter DT. Neurorestoration Induced by the HDAC Inhibitor Sodium Valproate in the Lactacystin Model of Parkinson's is Associated with Histone Acetylation and Upregulation of Neurotrophic Factors. British Journal of Pharmacology. PMID 26040297 DOI: 10.1111/Bph.13208  0.689
2015 Di Fruscia P, Zacharioudakis E, Liu C, Moniot S, Laohasinnarong S, Khongkow M, Harrison IF, Koltsida K, Reynolds CR, Schmidtkunz K, Jung M, Chapman KL, Steegborn C, Dexter DT, Sternberg MJ, et al. The discovery of a highly selective 5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one SIRT2 inhibitor that is neuroprotective in an in vitro Parkinson's disease model. Chemmedchem. 10: 69-82. PMID 25395356 DOI: 10.1002/Cmdc.201402431  0.613
2015 Pienaar IS, Harrison IF, Elson JL, Bury A, Woll P, Simon AK, Dexter DT. An animal model mimicking pedunculopontine nucleus cholinergic degeneration in Parkinson's disease. Brain Structure & Function. 220: 479-500. PMID 24292256 DOI: 10.1007/S00429-013-0669-5  0.654
2015 Harrison IF, Machhada A, Colgan N, Ismail O, O'Callaghan JM, Holmes H, Wells JA, Gourine AV, Murray TK, Ahmed Z, Johnson RA, Collins EC, O'Neill MJ, Lythgoe MF. Glymphatic clearance impaired in a mouse model of tauopathy: Captured using contrast-enhanced MRI Alzheimers & Dementia. 11: 544. DOI: 10.1016/J.Jalz.2015.06.688  0.324
2015 Ismail O, Holmes H, Colgan N, Ma D, Wells JA, Powell NM, O'Callaghan JM, Harrison IF, Walker-Samuel S, Cardoso JM, Modat M, Fisher E, Ourselin S, Murray TK, Ahmed Z, et al. A multiscale MRI approach to investigate novel drug treatment strategies in mouse models of Alzheimer's disease Alzheimers & Dementia. 11: 226. DOI: 10.1016/J.Jalz.2015.06.181  0.365
2013 Harrison IF, Dexter DT. Epigenetic targeting of histone deacetylase: therapeutic potential in Parkinson's disease? Pharmacology & Therapeutics. 140: 34-52. PMID 23711791 DOI: 10.1016/J.Pharmthera.2013.05.010  0.663
2013 Katsouri L, Vizcaychipi MP, McArthur S, Harrison I, Suárez-Calvet M, Lleo A, Lloyd DG, Ma D, Sastre M. Prazosin, an α(1)-adrenoceptor antagonist, prevents memory deterioration in the APP23 transgenic mouse model of Alzheimer's disease. Neurobiology of Aging. 34: 1105-15. PMID 23063647 DOI: 10.1016/J.Neurobiolaging.2012.09.010  0.359
2011 Harrison I, Dexter D. Magnetic Resonance Imaging as a tool for longitudinal monitoring in the lactacystin model of Parkinson's disease and studying the neuroprotective effects of valproate F1000research. 2. DOI: 10.7490/F1000Research.1089305.1  0.678
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