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Janet E. Mertz - Publications

Affiliations: 
University of Wisconsin, Madison, Madison, WI 
Area:
Transcriptional regulation in DNA tumor viruses and breast cancer
Website:
https://cancerbiology.wisc.edu/bio/mertz_j.html

72 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Kraus RJ, Cordes BA, Sathiamoorthi S, Patel P, Yuan X, Iempridee T, Yu X, Lee DL, Lambert PF, Mertz JE. Reactivation of Epstein-Barr Virus By HIF-1α Requires p53. Journal of Virology. PMID 32641480 DOI: 10.1128/Jvi.00722-20  0.751
2017 Kraus RJ, Yu X, Cordes BA, Sathiamoorthi S, Iempridee T, Nawandar DM, Ma S, Romero-Masters JC, McChesney KG, Lin Z, Makielski KR, Lee DL, Lambert PF, Johannsen EC, Kenney SC, ... Mertz JE, et al. Hypoxia-inducible factor-1α plays roles in Epstein-Barr virus's natural life cycle and tumorigenesis by inducing lytic infection through direct binding to the immediate-early BZLF1 gene promoter. Plos Pathogens. 13: e1006404. PMID 28617871 DOI: 10.1371/Journal.Ppat.1006404  0.758
2017 Zou J, Jones RJ, Mertz JE, Wang H, Kuiatse I, Sullivan B, Fung L, Richard N, Erdman P, Torres E, Chourasia AH, Chan KW, Mercurio F, Stirling DI, Orlowski RZ. Protein Homeostatic Modulators, a Novel Class of Cereblon-Targeting Small Molecules As Potential Clinical Candidates in Multiple Myeloma Blood. 130: 4418-4418. DOI: 10.1182/Blood.V130.Suppl_1.4418.4418  0.333
2016 Jones RJ, Iempridee T, Wang X, Lee HC, Mertz JE, Kenney SC, Lin HY, Baladandayuthapani V, Dawson C, Shah J, Weber D, Orlowski RZ. Lenalidomide, Thalidomide, and Pomalidomide Reactivate the Epstein-Barr Virus Lytic Cycle Through Phosphoinositide 3-kinase Signaling and Ikaros Expression. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27297582 DOI: 10.1158/1078-0432.Ccr-15-2242  0.732
2015 Nawandar DM, Wang A, Makielski K, Lee D, Ma S, Barlow E, Reusch J, Jiang R, Wille CK, Greenspan D, Greenspan JS, Mertz JE, Hutt-Fletcher L, Johannsen EC, Lambert PF, et al. Differentiation-Dependent KLF4 Expression Promotes Lytic Epstein-Barr Virus Infection in Epithelial Cells. Plos Pathogens. 11: e1005195. PMID 26431332 DOI: 10.1371/Journal.Ppat.1005195  0.429
2015 Reusch JA, Nawandar DM, Wright KL, Kenney SC, Mertz JE. Cellular differentiation regulator BLIMP1 induces Epstein-Barr virus lytic reactivation in epithelial and B cells by activating transcription from both the R and Z promoters. Journal of Virology. 89: 1731-43. PMID 25410866 DOI: 10.1128/Jvi.02781-14  0.472
2014 Iempridee T, Reusch JA, Riching A, Johannsen EC, Dovat S, Kenney SC, Mertz JE. Epstein-Barr virus utilizes Ikaros in regulating its latent-lytic switch in B cells. Journal of Virology. 88: 4811-27. PMID 24522918 DOI: 10.1128/Jvi.03706-13  0.771
2014 Kenney SC, Mertz JE. Regulation of the latent-lytic switch in Epstein-Barr virus. Seminars in Cancer Biology. 26: 60-8. PMID 24457012 DOI: 10.1016/J.Semcancer.2014.01.002  0.388
2012 Das S, Becker BN, Hoffmann FM, Mertz JE. Reversal of transforming growth factor-β induced epithelial-to-mesenchymal transition and the ZEB proteins. Fibrogenesis & Tissue Repair. 5: S28. PMID 23259633 DOI: 10.1186/1755-1536-5-S1-S28  0.508
2012 Ma SD, Yu X, Mertz JE, Gumperz JE, Reinheim E, Zhou Y, Tang W, Burlingham WJ, Gulley ML, Kenney SC. An Epstein-Barr Virus (EBV) mutant with enhanced BZLF1 expression causes lymphomas with abortive lytic EBV infection in a humanized mouse model. Journal of Virology. 86: 7976-87. PMID 22623780 DOI: 10.1128/Jvi.00770-12  0.417
2012 Yu X, McCarthy PJ, Wang Z, Gorlen DA, Mertz JE. Shutoff of BZLF1 gene expression is necessary for immortalization of primary B cells by Epstein-Barr virus. Journal of Virology. 86: 8086-96. PMID 22623769 DOI: 10.1128/Jvi.00234-12  0.47
2012 Esch AM, Thompson NE, Lamberski JA, Mertz JE, Burgess RR. Production and characterization of monoclonal antibodies to estrogen-related receptor alpha (ERRα) and use in immunoaffinity chromatography. Protein Expression and Purification. 84: 47-58. PMID 22565152 DOI: 10.1016/J.Pep.2012.04.020  0.668
2011 Iempridee T, Das S, Xu I, Mertz JE. Transforming growth factor beta-induced reactivation of Epstein-Barr virus involves multiple Smad-binding elements cooperatively activating expression of the latent-lytic switch BZLF1 gene. Journal of Virology. 85: 7836-48. PMID 21593157 DOI: 10.1128/Jvi.01197-10  0.78
2011 Yu X, McCarthy PJ, Lim HJ, Iempridee T, Kraus RJ, Gorlen DA, Mertz JE. The ZIIR element of the Epstein-Barr virus BZLF1 promoter plays a central role in establishment and maintenance of viral latency. Journal of Virology. 85: 5081-90. PMID 21389123 DOI: 10.1128/Jvi.02615-10  0.764
2010 Ellis-Connell AL, Iempridee T, Xu I, Mertz JE. Cellular microRNAs 200b and 429 regulate the Epstein-Barr virus switch between latency and lytic replication. Journal of Virology. 84: 10329-43. PMID 20668090 DOI: 10.1128/Jvi.00923-10  0.731
2010 Ellis AL, Wang Z, Yu X, Mertz JE. Either ZEB1 or ZEB2/SIP1 can play a central role in regulating the Epstein-Barr virus latent-lytic switch in a cell-type-specific manner. Journal of Virology. 84: 6139-52. PMID 20375168 DOI: 10.1128/Jvi.02706-09  0.709
2010 Hagemeier SR, Dickerson SJ, Meng Q, Yu X, Mertz JE, Kenney SC. Sumoylation of the Epstein-Barr virus BZLF1 protein inhibits its transcriptional activity and is regulated by the virus-encoded protein kinase. Journal of Virology. 84: 4383-94. PMID 20181712 DOI: 10.1128/Jvi.02369-09  0.436
2010 Berg P, Mertz JE. Personal reflections on the origins and emergence of recombinant DNA technology. Genetics. 184: 9-17. PMID 20061565 DOI: 10.1534/Genetics.109.112144  0.454
2009 Das S, Becker BN, Hoffmann FM, Mertz JE. Complete reversal of epithelial to mesenchymal transition requires inhibition of both ZEB expression and the Rho pathway. Bmc Cell Biology. 10: 94. PMID 20025777 DOI: 10.1186/1471-2121-10-94  0.524
2007 Yu X, Wang Z, Mertz JE. ZEB1 regulates the latent-lytic switch in infection by Epstein-Barr virus. Plos Pathogens. 3: e194. PMID 18085824 DOI: 10.1371/Journal.Ppat.0030194  0.455
2007 Vu EH, Kraus RJ, Mertz JE. Phosphorylation-dependent sumoylation of estrogen-related receptor alpha1. Biochemistry. 46: 9795-804. PMID 17676930 DOI: 10.1021/Bi700316G  0.744
2007 Feng WH, Kraus RJ, Dickerson SJ, Lim HJ, Jones RJ, Yu X, Mertz JE, Kenney SC. ZEB1 and c-Jun levels contribute to the establishment of highly lytic Epstein-Barr virus infection in gastric AGS cells. Journal of Virology. 81: 10113-22. PMID 17626078 DOI: 10.1128/Jvi.00692-07  0.406
2007 Ariazi EA, Kraus RJ, Farrell ML, Jordan VC, Mertz JE. Estrogen-related receptor alpha1 transcriptional activities are regulated in part via the ErbB2/HER2 signaling pathway. Molecular Cancer Research : McR. 5: 71-85. PMID 17259347 DOI: 10.1158/1541-7786.Mcr-06-0227  0.424
2005 Guang S, Felthauser AM, Mertz JE. Binding of hnRNP L to the pre-mRNA processing enhancer of the herpes simplex virus thymidine kinase gene enhances both polyadenylation and nucleocytoplasmic export of intronless mRNAs. Molecular and Cellular Biology. 25: 6303-13. PMID 16024770 DOI: 10.1128/Mcb.25.15.6303-6313.2005  0.615
2005 Guang S, Mertz JE. Pre-mRNA processing enhancer (PPE) elements from intronless genes play additional roles in mRNA biogenesis than do ones from intron-containing genes. Nucleic Acids Research. 33: 2215-26. PMID 15843684 DOI: 10.1093/Nar/Gki506  0.623
2003 Yu X, Mertz JE. Distinct modes of regulation of transcription of hepatitis B virus by the nuclear receptors HNF4alpha and COUP-TF1. Journal of Virology. 77: 2489-99. PMID 12551987 DOI: 10.1128/Jvi.77.4.2489-2499.2003  0.434
2003 Kraus RJ, Perrigoue JG, Mertz JE. ZEB negatively regulates the lytic-switch BZLF1 gene promoter of Epstein-Barr virus. Journal of Virology. 77: 199-207. PMID 12477825 DOI: 10.1128/Jvi.77.1.199-207.2003  0.475
2002 Farrell ML, Mertz JE. Hormone response element in SV40 late promoter directly affects synthesis of early as well as late viral RNAs. Virology. 297: 307-18. PMID 12083829 DOI: 10.1006/Viro.2002.1478  0.447
2002 Farrell ML, Mertz JE. Cell type-specific replication of simian virus 40 conferred by hormone response elements in the late promoter. Journal of Virology. 76: 6762-70. PMID 12050389 DOI: 10.1128/Jvi.76.13.6762-6770.2002  0.454
2002 Kraus RJ, Ariazi EA, Farrell ML, Mertz JE. Estrogen-related receptor alpha 1 actively antagonizes estrogen receptor-regulated transcription in MCF-7 mammary cells. The Journal of Biological Chemistry. 277: 24826-34. PMID 11986328 DOI: 10.1074/Jbc.M202952200  0.402
2001 Yu X, Mertz JE. Critical roles of nuclear receptor response elements in replication of hepatitis B virus. Journal of Virology. 75: 11354-64. PMID 11689616 DOI: 10.1128/Jvi.75.23.11354-11364.2001  0.422
2001 Kraus RJ, Shadley L, Mertz JE. Nuclear factor 1 family members mediate repression of the BK virus late promoter. Virology. 287: 89-104. PMID 11504545 DOI: 10.1006/Viro.2001.1024  0.439
2001 Kraus RJ, Mertz JE. Cell-free transcription of SV40. Methods in Molecular Biology (Clifton, N.J.). 165: 69-85. PMID 11217396 DOI: 10.1385/1-59259-117-5:69  0.372
2001 Kraus RJ, Mirocha SJ, Stephany HM, Puchalski JR, Mertz JE. Identification of a novel element involved in regulation of the lytic switch BZLF1 gene promoter of Epstein-Barr virus. Journal of Virology. 75: 867-77. PMID 11134300 DOI: 10.1128/Jvi.75.2.867-877.2001  0.477
1997 Yu X, Mertz JE. Differential regulation of the pre-C and pregenomic promoters of human hepatitis B virus by members of the nuclear receptor superfamily. Journal of Virology. 71: 9366-74. PMID 9371596 DOI: 10.1128/Jvi.71.12.9366-9374.1997  0.41
1997 Johnston SD, Liu X, Zuo F, Eisenbraun TL, Wiley SR, Kraus RJ, Mertz JE. Estrogen-related receptor alpha 1 functionally binds as a monomer to extended half-site sequences including ones contained within estrogen-response elements. Molecular Endocrinology (Baltimore, Md.). 11: 342-52. PMID 9058380 DOI: 10.1210/Mend.11.3.9897  0.368
1997 Zuo F, Kraus RJ, Gulick T, Moore DD, Mertz JE. Direct modulation of simian virus 40 late gene expression by thyroid hormone and its receptor. Journal of Virology. 71: 427-36. PMID 8985367  0.317
1996 Yu X, Mertz JE. Promoters for synthesis of the pre-C and pregenomic mRNAs of human hepatitis B virus are genetically distinct and differentially regulated. Journal of Virology. 70: 8719-26. PMID 8970999 DOI: 10.1128/Jvi.70.12.8719-8726.1996  0.439
1996 Liu X, Mertz JE. Sequence of the polypyrimidine tract of the 3'-terminal 3' splicing signal can affect intron-dependent pre-mRNA processing in vivo. Nucleic Acids Research. 24: 1765-73. PMID 8649998 DOI: 10.1093/Nar/24.9.1765  0.343
1996 Kraus RJ, Murray EE, Wiley SR, Zink NM, Loritz K, Gelembiuk GW, Mertz JE. Experimentally determined weight matrix definitions of the initiator and TBP binding site elements of promoters. Nucleic Acids Research. 24: 1531-9. PMID 8628688 DOI: 10.1093/Nar/24.8.1531  0.365
1996 Johnston SD, Yu XM, Mertz JE. The major transcriptional transactivation domain of simian virus 40 large T antigen associates nonconcurrently with multiple components of the transcriptional preinitiation complex. Journal of Virology. 70: 1191-202. PMID 8551580 DOI: 10.1128/Jvi.70.2.1191-1202.1996  0.387
1995 Zuo F, Mertz JE. Simian virus 40 late gene expression is regulated by members of the steroid/thyroid hormone receptor superfamily. Proceedings of the National Academy of Sciences of the United States of America. 92: 8586-90. PMID 7567979 DOI: 10.1073/Pnas.92.19.8586  0.452
1995 Liu X, Mertz JE. HnRNP L binds a cis-acting RNA sequence element that enables intron-dependent gene expression. Genes & Development. 9: 1766-80. PMID 7542615 DOI: 10.1101/Gad.9.14.1766  0.369
1993 Liu X, Mertz JE. Polyadenylation site selection cannot occur in vivo after excision of the 3'-terminal intron. Nucleic Acids Research. 21: 5256-63. PMID 8255783 DOI: 10.1093/Nar/21.22.5256  0.354
1993 Wiley SR, Kraus RJ, Zuo F, Murray EE, Loritz K, Mertz JE. SV40 early-to-late switch involves titration of cellular transcriptional repressors. Genes & Development. 7: 2206-19. PMID 8224847 DOI: 10.1101/Gad.7.11.2206  0.462
1992 Wiley SR, Kraus RJ, Mertz JE. Functional binding of the "TATA" box binding component of transcription factor TFIID to the -30 region of TATA-less promoters. Proceedings of the National Academy of Sciences of the United States of America. 89: 5814-8. PMID 1321424 DOI: 10.1073/Pnas.89.13.5814  0.39
1991 Yu XM, Gelembiuk GW, Wang CY, Ryu WS, Mertz JE. Expression from herpesvirus promoters does not relieve the intron requirement for cytoplasmic accumulation of human beta-globin mRNA. Nucleic Acids Research. 19: 7231-4. PMID 1662815 DOI: 10.1093/Nar/19.25.7231  0.418
1990 Sedman SA, Gelembiuk GW, Mertz JE. Translation initiation at a downstream AUG occurs with increased efficiency when the upstream AUG is located very close to the 5' cap. Journal of Virology. 64: 453-7. PMID 2152833 DOI: 10.1128/Jvi.64.1.453-457.1990  0.317
1989 Ryu WS, Mertz JE. Simian virus 40 late transcripts lacking excisable intervening sequences are defective in both stability in the nucleus and transport to the cytoplasm. Journal of Virology. 63: 4386-94. PMID 2550672 DOI: 10.1128/Jvi.63.10.4386-4394.1989  0.383
1989 Sedman SA, Good PJ, Mertz JE. Leader-encoded open reading frames modulate both the absolute and relative rates of synthesis of the virion proteins of simian virus 40. Journal of Virology. 63: 3884-93. PMID 2548004 DOI: 10.1128/Jvi.63.9.3884-3893.1989  0.365
1988 Hertz GZ, Mertz JE. The enhancer elements and GGGCGG boxes of SV40 provide similar functions in bidirectionally promoting transcription. Virology. 163: 579-90. PMID 2833024 DOI: 10.1016/0042-6822(88)90299-1  0.388
1988 Good PJ, Welch RC, Barkan A, Somasekhar MB, Mertz JE. Both VP2 and VP3 are synthesized from each of the alternative spliced late 19S RNA species of simian virus 40. Journal of Virology. 62: 944-53. PMID 2828689 DOI: 10.1128/Jvi.62.3.944-953.1988  0.334
1988 Good PJ, Welch RC, Ryu WS, Mertz JE. The late spliced 19S and 16S RNAs of simian virus 40 can be synthesized from a common pool of transcripts. Journal of Virology. 62: 563-71. PMID 2826816 DOI: 10.1128/Jvi.62.2.563-571.1988  0.336
1987 Barkan A, Welch RC, Mertz JE. Missense mutations in the VP1 gene of simian virus 40 that compensate for defects caused by deletions in the viral agnogene. Journal of Virology. 61: 3190-8. PMID 3041040 DOI: 10.1128/Jvi.61.10.3190-3198.1987  0.375
1986 Hertz GZ, Mertz JE. Bidirectional promoter elements of simian virus 40 are required for efficient replication of the viral DNA. Molecular and Cellular Biology. 6: 3513-22. PMID 3025597  0.307
1985 Somasekhar MB, Mertz JE. Exon mutations that affect the choice of splice sites used in processing the SV40 late transcripts. Nucleic Acids Research. 13: 5591-609. PMID 2994004 DOI: 10.1093/Nar/13.15.5591  0.385
1984 Mertz JE. A detailed genetic analysis of the late complementation groups of simian virus 40. Virology. 132: 173-85. PMID 6320531 DOI: 10.1016/0042-6822(84)90101-6  0.361
1982 Mertz JE. Linear DNA does not form chromatin containing regularly spaced nucleosomes. Molecular and Cellular Biology. 2: 1608-18. PMID 14582201 DOI: 10.1128/Mcb.2.12.1608  0.339
1982 Miller TJ, Mertz JE. Template structural requirements for transcription in vivo by RNA polymerase II. Molecular and Cellular Biology. 2: 1595-607. PMID 14582200 DOI: 10.1128/Mcb.2.12.1595  0.395
1982 Miller TJ, Stephens DL, Mertz JE. Kinetics of accumulation and processing of simian virus 40 RNA in Xenopus laevis oocytes injected with simian virus 40 DNA. Molecular and Cellular Biology. 2: 1581-94. PMID 14582199 DOI: 10.1128/Mcb.2.12.1581  0.374
1982 Johnson AD, Barkan A, Mertz JE. Nucleotide sequence analysis of the recombinant joints in 16 naturally arising deletion mutants of simian virus 40. Virology. 123: 464-9. PMID 6294985 DOI: 10.1016/0042-6822(82)90281-1  0.322
1982 Ghosh PK, Piatak M, Mertz JE, Weissman SM, Lebowitz P. Altered utilization of splice sites and 5' termini in late RNAs produced by leader region mutants of simian virus 40. Journal of Virology. 44: 610-24. PMID 6292521 DOI: 10.1128/Jvi.44.2.610-624.1982  0.354
1981 Ghosh PK, Roy P, Barkan A, Mertz JE, Weissman SM, Lebowitz P. Unspliced functional late 19S mRNAs containing intervening sequences are produced by a late leader mutant of simian virus 40. Proceedings of the National Academy of Sciences of the United States of America. 78: 1386-90. PMID 6262793 DOI: 10.1073/Pnas.78.3.1386  0.366
1978 Kinniburgh AJ, Mertz JE, Ross J. The precursor of mouse beta-globin messenger RNA contains two intervening RNA sequences. Cell. 14: 681-93. PMID 688388 DOI: 10.1016/0092-8674(78)90251-9  0.304
1978 Laskey RA, Honda BM, Mills AD, Morris NR, Wyllie AH, Mertz JE, De Roberts EM, Gurdon JB. Chromatin assembly and transcription in eggs and oocytes of Xenopus laevis. Cold Spring Harbor Symposia On Quantitative Biology. 42: 171-8. PMID 209936 DOI: 10.1101/Sqb.1978.042.01.019  0.637
1977 de Robertis EM, Gurdon JB, Partington GA, Mertz JE, Laskey RA. Injected amphibian oocytes: a living test tube for the study of eukaryotic gene transcription? Biochemical Society Symposium. 181-91. PMID 339919  0.718
1977 De Robertis EM, Mertz JE. Coupled transcription-translation of DNA injected into Xenopus oocytes. Cell. 12: 175-82. PMID 198138 DOI: 10.1016/0092-8674(77)90195-7  0.583
1977 Mertz JE, Gurdon JB. Purified DNAs are transcribed after microinjection into Xenopus oocytes. Proceedings of the National Academy of Sciences of the United States of America. 74: 1502-6. PMID 193103 DOI: 10.1073/Pnas.74.4.1502  0.546
1975 Mertz JE, Carbon J, Herzberg M, Davis RW, Berg P. Isolation and characterization of individual clones of simian virus 40 mutants containing deletions duplications and insertions in their DNA. Cold Spring Harbor Symposia On Quantitative Biology. 39: 69-84. PMID 169098 DOI: 10.1101/Sqb.1974.039.01.012  0.518
1974 Berg DE, Jackson DA, Mertz JE. Isolation of a lambda dv plasmid carrying the bacterial gal operon. Journal of Virology. 14: 1063-9. PMID 4610174 DOI: 10.1128/Jvi.14.5.1063-1069.1974  0.318
1974 Mertz JE, Berg P. Viable deletion mutants of simian virus 40: selective isolation by means of a restriction endonuclease from Hemophilus parainfluenzae. Proceedings of the National Academy of Sciences of the United States of America. 71: 4879-83. PMID 4373732 DOI: 10.1073/Pnas.71.12.4879  0.523
1974 Mertz JE, Berg P. Defective simian virus 40 genomes: isolation and growth of individual clones. Virology. 62: 112-24. PMID 4370797 DOI: 10.1016/0042-6822(74)90307-9  0.496
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