Sanford H. Leuba - Publications

Affiliations: 
University of Pittsburgh, Pittsburgh, PA, United States 
Area:
General Biophysics, Cell Biology, Molecular Biology

59 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Carrasco C, Pastrana CL, Aicart-Ramos C, Leuba SH, Khan SA, Moreno-Herrero F. Dynamics of DNA nicking and unwinding by the RepC-PcrA complex. Nucleic Acids Research. PMID 31930301 DOI: 10.1093/Nar/Gkz1200  0.511
2018 Chirico G, Gansen A, Leuba SH, Olins AL, Olins DE, Smith JC, Tóth K. Jörg Langowski: his scientific legacy and the future it promises. Bmc Biophysics. 11: 5. PMID 30026939 DOI: 10.1186/S13628-018-0045-1  0.341
2017 Carney SM, Gomathinayagam S, Leuba SH, Trakselis MA. Bacterial DnaB helicase interacts with the excluded strand to regulate unwinding. The Journal of Biological Chemistry. PMID 28939774 DOI: 10.1074/Jbc.M117.814178  0.493
2017 Pastrana CL, Carrasco C, Akthar P, Leuba SH, Khan SA, Moreno-Herrero F. Towards Rolling-Circle Replication at the Single-Molecule Level Biophysical Journal. 112: 372a. DOI: 10.1016/J.Bpj.2016.11.2019  0.347
2016 Pastrana CL, Carrasco C, Akhtar P, Leuba SH, Khan SA, Moreno-Herrero F. Force and twist dependence of RepC nicking activity on torsionally-constrained DNA molecules. Nucleic Acids Research. PMID 27488190 DOI: 10.1093/Nar/Gkw689  0.521
2016 Carney SM, Leuba SH, Trakselis MA. The Role of the Excluded Strand in Hexameric Helicase Unwinding Biophysical Journal. 110: 62a. DOI: 10.1016/J.Bpj.2015.11.402  0.465
2015 Carney SM, Leuba S, Trakselis M. Mechanistic Insights of Hexameric Helicase Function Provided by Single-Molecule FRET Biophysical Journal. 108: 67a. DOI: 10.1016/J.Bpj.2014.11.401  0.501
2014 Schauer GD, Huber KD, Leuba SH, Sluis-Cremer N. Mechanism of allosteric inhibition of HIV-1 reverse transcriptase revealed by single-molecule and ensemble fluorescence. Nucleic Acids Research. 42: 11687-96. PMID 25232099 DOI: 10.1093/Nar/Gku819  0.353
2014 Rodriguez-Collazo P, Leuba S, Karahanian E, Zlatanova J. Salt-urea, sulfopropyl-sepharose, and covalent chromatography methods for histone isolation and fractionation. Methods in Molecular Biology (Clifton, N.J.). 1094: 295-307. PMID 24162997 DOI: 10.1007/978-1-62703-706-8_23  0.347
2013 Schauer GD, Sluis-Cremer N, Leuba SH. Measurements of the Functional Dynamics of Wild Type and K103N HIV-1 Reverse Transcriptase Reveal the Mechanism of Efavirenz Resistance Biophysical Journal. 104: 420a-421a. DOI: 10.1016/J.Bpj.2012.11.2342  0.322
2012 Fagerburg MV, Schauer GD, Thickman KR, Bianco PR, Khan SA, Leuba SH, Anand SP. PcrA-mediated disruption of RecA nucleoprotein filaments--essential role of the ATPase activity of RecA. Nucleic Acids Research. 40: 8416-24. PMID 22743269 DOI: 10.1093/Nar/Gks641  0.748
2012 Lan L, Nakajima S, Kapetanaki MG, Hsieh CL, Fagerburg M, Thickman K, Rodriguez-Collazo P, Leuba SH, Levine AS, Rapi?-Otrin V. Monoubiquitinated histone H2A destabilizes photolesion-containing nucleosomes with concomitant release of UV-damaged DNA-binding protein E3 ligase. The Journal of Biological Chemistry. 287: 12036-49. PMID 22334663 DOI: 10.1074/Jbc.M111.307058  0.745
2012 Schauer GD, Sluis-Cremer N, Leuba SH. Direct Measurement of HIV-1 Reverse Transcriptase Binding Kinetics, One Complex at a Time Biophysical Journal. 102: 484a. DOI: 10.1016/J.Bpj.2011.11.2651  0.414
2011 Fagerburg MV, Leuba SH. Optimal practices for surface-tethered single molecule total internal reflection fluorescence resonance energy transfer analysis. Methods in Molecular Biology (Clifton, N.J.). 749: 273-89. PMID 21674379 DOI: 10.1007/978-1-61779-142-0_19  0.714
2011 Graham BW, Schauer GD, Leuba SH, Trakselis MA. Steric exclusion and wrapping of the excluded DNA strand occurs along discrete external binding paths during MCM helicase unwinding. Nucleic Acids Research. 39: 6585-95. PMID 21576224 DOI: 10.1093/Nar/Gkr345  0.51
2011 Schauer G, Pestov N, Fagerburg MV, Studitsky V, Leuba SH. Transcription in Chromatin: Single-Molecule Observation of Active Mononucleosomal Elongation Complexes Biophysical Journal. 100: 66a. DOI: 10.1016/J.Bpj.2010.12.558  0.741
2011 Fagerburg MV, Anand SP, Schauer G, Khan SA, Leuba SH. Holliday Junction as Single Molecule System for Studying Protein Binding Biophysical Journal. 100: 478a. DOI: 10.1016/J.Bpj.2010.12.2802  0.719
2010 Thickman KR, Leuba SH, Khan SA. DNA Structure Specificity of Bacillus Stearothermophilus PcrA Biophysical Journal. 98. DOI: 10.1016/J.Bpj.2009.12.415  0.478
2010 Leuba SH, Anand SP, Fagerburg M, Schauer G, Thickman K, Khan S. Following the Motions of a DNA Helicase on DNA in Real Time Biophysical Journal. 98: 591a. DOI: 10.1016/J.Bpj.2009.12.3216  0.753
2009 Cheng CM, Kim Y, Yang JM, Leuba SH, Leduc PR. Dynamics of individual polymers using microfluidic based microcurvilinear flow. Lab On a Chip. 9: 2339-47. PMID 19636465 DOI: 10.1039/B907860F  0.383
2009 Rodriguez-Collazo P, Leuba SH, Zlatanova J. Robust methods for purification of histones from cultured mammalian cells with the preservation of their native modifications. Nucleic Acids Research. 37: e81. PMID 19443446 DOI: 10.1093/Nar/Gkp273  0.405
2009 Leuba SH, Wheeler TB, Cheng CM, LeDuc PR, Fernández-Sierra M, Quiñones E. Structure and dynamics of single DNA molecules manipulated by magnetic tweezers and or flow. Methods (San Diego, Calif.). 47: 214-22. PMID 19015032 DOI: 10.1016/J.Ymeth.2008.10.022  0.431
2008 Leuba SH, Anand SP, Harp JM, Khan SA. Expedient placement of two fluorescent dyes for investigating dynamic DNA protein interactions in real time. Chromosome Research : An International Journal On the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology. 16: 451-67. PMID 18461484 DOI: 10.1007/S10577-008-1235-5  0.56
2007 Anand SP, Zheng H, Bianco PR, Leuba SH, Khan SA. DNA helicase activity of PcrA is not required for the displacement of RecA protein from DNA or inhibition of RecA-mediated strand exchange. Journal of Bacteriology. 189: 4502-9. PMID 17449621 DOI: 10.1128/Jb.00376-07  0.514
2007 Zheng H, Goldner LS, Leuba SH. Homebuilt single-molecule scanning confocal fluorescence microscope studies of single DNA/protein interactions. Methods (San Diego, Calif.). 41: 342-52. PMID 17309845 DOI: 10.1016/J.Ymeth.2006.11.008  0.469
2006 Zlatanova J, McAllister WT, Borukhov S, Leuba SH. Single-molecule approaches reveal the idiosyncrasies of RNA polymerases. Structure (London, England : 1993). 14: 953-66. PMID 16765888 DOI: 10.1016/J.Str.2006.03.016  0.409
2005 Pomerantz RT, Ramjit R, Gueroui Z, Place C, Anikin M, Leuba S, Zlatanova J, McAllister WT. A tightly regulated molecular motor based upon T7 RNA polymerase. Nano Letters. 5: 1698-703. PMID 16159208 DOI: 10.1021/Nl0509125  0.385
2005 Tomschik M, Zheng H, van Holde K, Zlatanova J, Leuba SH. Fast, long-range, reversible conformational fluctuations in nucleosomes revealed by single-pair fluorescence resonance energy transfer. Proceedings of the National Academy of Sciences of the United States of America. 102: 3278-83. PMID 15728351 DOI: 10.1073/Pnas.0500189102  0.568
2004 Leuba SH, Bennink ML, Zlatanova J. Single-molecule analysis of chromatin. Methods in Enzymology. 376: 73-105. PMID 14975300 DOI: 10.1016/S0076-6879(03)76006-6  0.319
2004 Zlatanova J, Leuba SH. Chromatin structure and dynamics: lessons from single molecule approaches New Comprehensive Biochemistry. 39: 369-396. DOI: 10.1016/S0167-7306(03)39014-3  0.369
2003 Zlatanova J, Leuba SH. Magnetic tweezers: a sensitive tool to study DNA and chromatin at the single-molecule level. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 81: 151-9. PMID 12897848 DOI: 10.1139/O03-048  0.449
2003 Zlatanova J, Leuba SH. Chromatin fibers, one-at-a-time. Journal of Molecular Biology. 331: 1-19. PMID 12875831 DOI: 10.1016/S0022-2836(03)00691-0  0.517
2003 Leuba SH, Karymov MA, Tomschik M, Ramjit R, Smith P, Zlatanova J. Assembly of single chromatin fibers depends on the tension in the DNA molecule: magnetic tweezers study. Proceedings of the National Academy of Sciences of the United States of America. 100: 495-500. PMID 12522259 DOI: 10.1073/Pnas.0136890100  0.386
2002 Zlatanova J, Leuba SH. Stretching and imaging single DNA molecules and chromatin. Journal of Muscle Research and Cell Motility. 23: 377-95. PMID 12785092 DOI: 10.1023/A:1023498120458  0.464
2002 Leuba SH, Zlatanova J. Single-molecule studies of chromatin fibers: a personal report. Archives of Histology and Cytology. 65: 391-403. PMID 12680455 DOI: 10.1679/Aohc.65.391  0.402
2002 An W, Palhan VB, Karymov MA, Leuba SH, Roeder RG. Selective requirements for histone H3 and H4 N termini in p300-dependent transcriptional activation from chromatin. Molecular Cell. 9: 811-21. PMID 11983172 DOI: 10.1016/S1097-2765(02)00497-5  0.379
2001 Tomschik M, Karymov MA, Zlatanova J, Leuba SH. The archaeal histone-fold protein HMf organizes DNA into bona fide chromatin fibers Structure. 9: 1201-1211. PMID 11738046 DOI: 10.1016/S0969-2126(01)00682-7  0.439
2001 Karymov MA, Tomschik M, Leuba SH, Caiafa P, Zlatanova J. DNA methylation-dependent chromatin fiber compaction in vivo and in vitro: Requirement for linker histone Faseb Journal. 15: 2631-2641. PMID 11726539 DOI: 10.1096/Fj.01-0345Com  0.455
2001 Bennink ML, Leuba SH, Leno GH, Zlatanova J, De Grooth BG, Greve J. Unfolding individual nucleosomes by stretching single chromatin fibers with optical tweezers Nature Structural Biology. 8: 606-610. PMID 11427891 DOI: 10.1038/89646  0.432
2001 Bennink M, Pope L, Leuba S, de Grooth B, Greve J. Single Chromatin Fibre Assembly Using Optical Tweezers Single Molecules. 2: 91-97. DOI: 10.1002/1438-5171(200107)2:2<91::Aid-Simo91>3.0.Co;2-S  0.512
2000 Leuba S, Zlatanova J, Karymov M, Bash R, Liu Y, Lohr D, Harrington R, Lindsay S. The Mechanical Properties of Single Chromatin Fibers Under Tension Single Molecules. 1: 185-192. DOI: 10.1002/1438-5171(200006)1:2<185::Aid-Simo185>3.0.Co;2-8  0.427
1999 Zlatanova J, Leuba SH, Van Holde K. Chromatin structure revisited Critical Reviews in Eukaryotic Gene Expression. 9: 245-255. PMID 10651241 DOI: 10.1615/Critreveukargeneexpr.V9.I3-4.90  0.393
1999 An W, Zlatanova J, Leuba SH, Van Holde K. The site of binding of linker histone to the nucleosome does not depend upon the amino termini of core histones Biochimie. 81: 727-732. PMID 10492019 DOI: 10.1016/S0300-9084(99)80130-8  0.429
1999 Liu YZ, Leuba SH, Lindsay SM. Relationship between stiffness and force in single molecule pulling experiments Langmuir. 15: 8547-8548. DOI: 10.1021/La990267F  0.306
1998 Zlatanova J, Yaneva J, Leuba SH. Proteins that specifically recognize cisplatin-damaged DNA: A clue to anticancer activity of cisplatin Faseb Journal. 12: 791-799. PMID 9657519 DOI: 10.1096/Fasebj.12.10.791  0.414
1998 Leuba SH, Bustamante C, Van Holde K, Zlatanova J. Linker histone tails and N-tails of histone H3 are redundant: Scanning force microscopy studies of reconstituted fibers Biophysical Journal. 74: 2830-2839. PMID 9635737 DOI: 10.1016/S0006-3495(98)77990-1  0.369
1998 Leuba SH, Bustamante C, Zlatanova J, Van Holde K. Contributions of linker histones and histone H3 to chromatin structure: Scanning force microscopy studies on trypsinized fibers Biophysical Journal. 74: 2823-2829. PMID 9635736 DOI: 10.1016/S0006-3495(98)77989-5  0.332
1998 Zlatanova J, Leuba SH, Van Holde K. Chromatin fiber structure: Morphology, molecular determinants, structural transitions Biophysical Journal. 74: 2554-2566. PMID 9591681 DOI: 10.1016/S0006-3495(98)77963-9  0.321
1998 An W, Leuba SH, Van Holde K, Zlatanova J. Linker histone protects linker DNA on only one side of the core particle and in a sequence-dependent manner Proceedings of the National Academy of Sciences of the United States of America. 95: 3396-3401. PMID 9520377 DOI: 10.1073/Pnas.95.7.3396  0.449
1997 Yaneva J, Leuba SH, Van Holde K, Zlatanova J. The major chromatin protein histone H1 binds preferentially to cis- platinum-damaged DNA Proceedings of the National Academy of Sciences of the United States of America. 94: 13448-13451. PMID 9391045 DOI: 10.1073/Pnas.94.25.13448  0.443
1997 Bustamante C, Zuccheri G, Leuba SH, Yang G, Samori B. Visualization and analysis of chromatin by scanning force microscopy. Methods (San Diego, Calif.). 12: 73-83. PMID 9169197 DOI: 10.1006/Meth.1997.0449  0.37
1994 Leuba SH, Zlatanova J, Van Holde K. On the location of linker DNA in the chromatin fiber: Studies with immobilized and soluble micrococcal nuclease Journal of Molecular Biology. 235: 871-880. PMID 8289325 DOI: 10.1006/Jmbi.1994.1045  0.389
1994 Zlatanova J, Leuba SH, Yang G, Bustamante C, Van Holde K. Linker DNA accessibility in chromatin fibers of different conformations: A revaluation Proceedings of the National Academy of Sciences of the United States of America. 91: 5277-5280. PMID 8202481 DOI: 10.1073/Pnas.91.12.5277  0.376
1994 Varga-Weisz P, Zlatanova J, Leuba SH, Schroth GP, Van Holde K. Binding of histones H1 and H5 and their globular domains to four-way junction DNA Proceedings of the National Academy of Sciences of the United States of America. 91: 3525-3529. PMID 8170940 DOI: 10.1073/Pnas.91.9.3525  0.436
1994 Leuba SH, Yang G, Robert C, Samori B, van Holde K, Zlatanova J, Bustamante C. Three-dimensional structure of extended chromatin fibers as revealed by tapping-mode scanning force microscopy. Proceedings of the National Academy of Sciences of the United States of America. 91: 11621-5. PMID 7972114 DOI: 10.1073/Pnas.91.24.11621  0.313
1994 Yang G, Leuba SH, Bustamante C, Zlatanova J, van Holde K. Role of linker histones in extended chromatin fibre structure Nature Structural Biology. 1: 761-763. PMID 7634084 DOI: 10.1038/Nsb1194-761  0.363
1993 Krylov D, Leuba S, Van Holde K, Zlatanova J. Histones H1 and H5 interact preferentially with crossovers of double-helical DNA Proceedings of the National Academy of Sciences of the United States of America. 90: 5052-5056. PMID 8506351  0.409
1993 Leuba SH, Zlatanova J, Van Holde K. On the location of histones H1 and H5 in the chromatin fiber: Studies with immobilized trypsin and chymotrypsin Journal of Molecular Biology. 229: 917-929. PMID 8445656 DOI: 10.1006/Jmbi.1993.1096  0.347
1992 Garcia-Ramirez M, Leuba SH, Ausio J. One-step fractionation method for isolating H1 histones from chromatin under nondenaturing conditions. Protein Expression and Purification. 1: 40-4. PMID 2152183 DOI: 10.1016/1046-5928(90)90043-X  0.323
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