| Year |
Citation |
Score |
| 2024 |
Stanton C, Sun J, Nutsch K, Rosarda JD, Nguyen T, Li-Ma C, Njomen E, Melillo B, Kutseikin S, Saez E, Cravatt BF, Teijaro JR, Wiseman RL, Bollong MJ. Covalent Targeting As a Common Mechanism for Inhibiting NLRP3 Inflammasome Assembly. Acs Chemical Biology. PMID 38198472 DOI: 10.1021/acschembio.3c00330 |
0.332 |
|
| 2023 |
Bulos ML, Grzelak EM, Li-Ma C, Chen E, Hull M, Johnson KA, Bollong MJ. Pharmacological inhibition of CLK2 activates YAP by promoting alternative splicing of AMOTL2. Elife. 12. PMID 38126343 DOI: 10.7554/eLife.88508 |
0.657 |
|
| 2023 |
Nutsch K, Song L, Chen E, Hull M, Chatterjee AK, Chen JJ, Bollong MJ. A covalent inhibitor of the YAP-TEAD transcriptional complex identified by high-throughput screening. Rsc Chemical Biology. 4: 894-905. PMID 37920398 DOI: 10.1039/d3cb00044c |
0.397 |
|
| 2023 |
You S, Bollong MJ. A high throughput screen for pharmacological inhibitors of the carbohydrate response element. Scientific Data. 10: 676. PMID 37794069 DOI: 10.1038/s41597-023-02596-z |
0.349 |
|
| 2023 |
Grzelak EM, Elshan NGRD, Shao S, Bulos ML, Joseph SB, Chatterjee AK, Chen JJ, Nguyên-Trân V, Schultz PG, Bollong MJ. Pharmacological YAP activation promotes regenerative repair of cutaneous wounds. Proceedings of the National Academy of Sciences of the United States of America. 120: e2305085120. PMID 37399395 DOI: 10.1073/pnas.2305085120 |
0.442 |
|
| 2023 |
Stanton C, Sun J, Nutsch K, Rosarda JD, Nguyen T, Li-Ma C, Kutseikin S, Saez E, Teijaro JR, Wiseman RL, Bollong MJ. Covalent targeting as a common mechanism for inhibiting NLRP3 inflammasome assembly. Biorxiv : the Preprint Server For Biology. PMID 37398499 DOI: 10.1101/2023.06.01.543248 |
0.341 |
|
| 2023 |
Ko Y, Hong M, Lee S, Kumar M, Ibrahim L, Nutsch K, Stanton C, Sondermann P, Sandoval B, Bulos ML, Iaconelli J, Chatterjee AK, Wiseman RL, Schultz PG, Bollong MJ. S-lactoyl modification of KEAP1 by a reactive glycolytic metabolite activates NRF2 signaling. Proceedings of the National Academy of Sciences of the United States of America. 120: e2300763120. PMID 37155889 DOI: 10.1073/pnas.2300763120 |
0.803 |
|
| 2023 |
Bulos ML, Grzelak EM, Li-Ma C, Chen E, Hull M, Johnson KA, Bollong MJ. "Pharmacological inhibition of CLK2 activates YAP by promoting alternative splicing of AMOTL2". Biorxiv : the Preprint Server For Biology. PMID 37131806 DOI: 10.1101/2023.04.19.537449 |
0.657 |
|
| 2023 |
Jo J, Kim J, Ibrahim L, Kumar M, Iaconelli J, So Tran C, Ryong Moon H, Jung Y, Luke Wiseman R, Lairson LL, Chatterjee AK, Bollong MJ, Yun H. Optimization of 3-aminotetrahydrothiophene 1,1-dioxides with improved potency and efficacy as non-electrophilic antioxidant response element (ARE) activators. Bioorganic & Medicinal Chemistry Letters. 129306. PMID 37116763 DOI: 10.1016/j.bmcl.2023.129306 |
0.776 |
|
| 2022 |
Martínez-Peña F, Pearson AD, Tang EL, Kuburich NA, Mani SA, Schultz PG, Bollong MJ, Lairson LL. Synthesis and biological evaluation of novel FiVe1 derivatives as potent and selective agents for the treatment of mesenchymal cancers. European Journal of Medicinal Chemistry. 242: 114638. PMID 36001933 DOI: 10.1016/j.ejmech.2022.114638 |
0.79 |
|
| 2021 |
Shalhout SZ, Yang PY, Grzelak EM, Nutsch K, Shao S, Zambaldo C, Iaconelli J, Ibrahim L, Stanton C, Chadwick SR, Chen E, DeRan M, Li S, Hull M, Wu X, ... ... Bollong MJ, et al. YAP-dependent proliferation by a small molecule targeting annexin A2. Nature Chemical Biology. PMID 33723431 DOI: 10.1038/s41589-021-00755-0 |
0.802 |
|
| 2021 |
Jo J, Ibrahim L, Iaconelli J, Kwak J, Kumar M, Jung Y, Lairson LL, Chatterjee AK, Schultz PG, Bollong MJ, Yun H. Discovery and SAR studies of 3-amino-4-(phenylsulfonyl)tetrahydrothiophene 1,1-dioxides as non-electrophilic antioxidant response element (ARE) activators. Bioorganic Chemistry. 108: 104614. PMID 33508678 DOI: 10.1016/j.bioorg.2020.104614 |
0.783 |
|
| 2021 |
Koh M, Ahmad I, Ko Y, Zhang Y, Martinez TF, Diedrich JK, Chu Q, Moresco JJ, Erb MA, Saghatelian A, Schultz PG, Bollong MJ. A short ORF-encoded transcriptional regulator. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33468658 DOI: 10.1073/pnas.2021943118 |
0.765 |
|
| 2020 |
Zambaldo C, Vinogradova EV, Qi X, Iaconelli J, Suciu RM, Koh M, Senkane K, Chadwick SR, Sanchez BB, Chen JS, Chatterjee AK, Liu P, Schultz PG, Cravatt BF, Bollong MJ. 2-Sulfonyl pyridines as tunable, cysteine-reactive electrophiles. Journal of the American Chemical Society. PMID 32302104 DOI: 10.1021/Jacs.0C02721 |
0.801 |
|
| 2020 |
Kuburich NA, Rosolen M, Martinez F, Hollander Pd, Bollong MJ, Soundararajan R, Lairson LL, Mani SA. Abstract 5043: A vimentin binding small molecule (FiVe1) is a novel candidate to target CSC-rich TNBC Cancer Research. 80: 5043-5043. DOI: 10.1158/1538-7445.Am2020-5043 |
0.716 |
|
| 2019 |
Iaconelli J, Chen E, Hull M, Schultz PG, Bollong M. Small molecule stimulators of NRF1 transcriptional activity. Chembiochem : a European Journal of Chemical Biology. PMID 31596542 DOI: 10.1002/Cbic.201900487 |
0.59 |
|
| 2019 |
Lucki NC, Villa GR, Vergani N, Bollong MJ, Beyer BA, Lee JW, Anglin JL, Spangenberg SH, Chin EN, Sharma A, Johnson K, Sander PN, Gordon P, Skirboll SL, Wurdak H, et al. A cell type-selective apoptosis-inducing small molecule for the treatment of brain cancer. Proceedings of the National Academy of Sciences of the United States of America. PMID 30846550 DOI: 10.1073/Pnas.1816626116 |
0.796 |
|
| 2019 |
Grandjean JMD, Plate L, Morimoto RI, Bollong MJ, Powers ET, Wiseman RL. Deconvoluting Stress-Responsive Proteostasis Signaling Pathways for Pharmacologic Activation using Targeted RNA-sequencing. Acs Chemical Biology. PMID 30821953 DOI: 10.1021/Acschembio.9B00134 |
0.409 |
|
| 2018 |
Bollong MJ, Lee G, Coukos JS, Yun H, Zambaldo C, Chang JW, Chin EN, Ahmad I, Chatterjee AK, Lairson LL, Schultz PG, Moellering RE. A metabolite-derived protein modification integrates glycolysis with KEAP1-NRF2 signalling. Nature. PMID 30323285 DOI: 10.1038/S41586-018-0622-0 |
0.762 |
|
| 2017 |
Bollong MJ, Pietilä M, Pearson AD, Sarkar TR, Ahmad I, Soundararajan R, Lyssiotis CA, Mani SA, Schultz PG, Lairson LL. A vimentin binding small molecule leads to mitotic disruption in mesenchymal cancers. Proceedings of the National Academy of Sciences of the United States of America. PMID 29087350 DOI: 10.1073/Pnas.1716009114 |
0.795 |
|
| 2017 |
Bollong MJ, Yang B, Vergani N, Beyer BA, Chin EN, Zambaldo C, Wang D, Chatterjee AK, Lairson LL, Schultz PG. Small molecule-mediated inhibition of myofibroblast transdifferentiation for the treatment of fibrosis. Proceedings of the National Academy of Sciences of the United States of America. 114: 4679-4684. PMID 28416697 DOI: 10.1073/Pnas.1702750114 |
0.786 |
|
| 2017 |
Yu S, Pearson A, Lim R, Rodgers D, Li S, Parker H, Weglarz M, Hampton E, Bollong M, Shen J, Zumbaldo C, Wang D, Woods A, Wright T, Schultz P, et al. P-262 A PDE4 Inhibitor-antibody Conjugate for Treating Ulcerative Colitis Inflammatory Bowel Diseases. 23. DOI: 10.1097/01.Mib.0000512805.98510.C0 |
0.715 |
|
| 2016 |
Yu S, Pearson AD, Lim RK, Rodgers DT, Li S, Parker HB, Weglarz M, Hampton EN, Bollong MJ, Shen J, Zambaldo C, Wang D, Woods AK, Wright TM, Schultz PG, et al. Targeted delivery of an anti-inflammatory PDE4 inhibitor to immune cells via an antibody-drug conjugate. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 27731313 DOI: 10.1038/Mt.2016.175 |
0.73 |
|
| 2015 |
Bollong MJ, Yun H, Sherwood L, Woods AK, Lairson LL, Schultz PG. A Small Molecule Inhibits Deregulated NRF2 Transcriptional Activity in Cancer. Acs Chemical Biology. 10: 2193-8. PMID 26270491 DOI: 10.1021/Acschembio.5B00448 |
0.815 |
|
| 2013 |
Chatterjee A, Xiao H, Bollong M, Ai HW, Schultz PG. Efficient viral delivery system for unnatural amino acid mutagenesis in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 110: 11803-8. PMID 23818609 DOI: 10.1073/Pnas.1309584110 |
0.762 |
|
| 2011 |
Staerk J, Lyssiotis CA, Medeiro LA, Bollong M, Foreman RK, Zhu S, Garcia M, Gao Q, Bouchez LC, Lairson LL, Charette BD, Supekova L, Janes J, Brinker A, Cho CY, et al. Pan-Src family kinase inhibitors replace Sox2 during the direct reprogramming of somatic cells. Angewandte Chemie (International Ed. in English). 50: 5734-6. PMID 21547985 DOI: 10.1002/Anie.201101042 |
0.747 |
|
| 2009 |
Lyssiotis CA, Foreman RK, Staerk J, Garcia M, Mathur D, Markoulaki S, Hanna J, Lairson LL, Charette BD, Bouchez LC, Bollong M, Kunick C, Brinker A, Cho CY, Schultz PG, et al. Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4. Proceedings of the National Academy of Sciences of the United States of America. 106: 8912-7. PMID 19447925 DOI: 10.1073/Pnas.0903860106 |
0.767 |
|
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