Brian A. McCool, B.S., Ph.D. - Publications

Physiology & Pharmacology Wake Forest University School of Medicine, Winston-Salem, NC, United States 
Alcohol neurobiology

64 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Price ME, McCool BA. Chronic Alcohol Dysregulates Glutamatergic Function in the Basolateral Amygdala in a Projection-and Sex-Specific Manner. Frontiers in Cellular Neuroscience. 16: 857550. PMID 35496915 DOI: 10.3389/fncel.2022.857550  0.73
2021 Price ME, McCool BA. Structural, Functional, and Behavioral Significance of Sex and Gonadal Hormones in the Basolateral Amygdala: A Review of Preclinical Literature. Alcohol (Fayetteville, N.Y.). PMID 34371120 DOI: 10.1016/j.alcohol.2021.08.001  0.718
2020 Sizer SE, Parrish BC, McCool BA. Chronic ethanol exposure potentiates cholinergic neurotransmission in the basolateral amygdala. Neuroscience. PMID 33385490 DOI: 10.1016/j.neuroscience.2020.12.014  0.834
2020 McGinnis MM, Parrish BC, McCool BA. Withdrawal from chronic ethanol exposure increases postsynaptic glutamate function of insular cortex projections to the rat basolateral amygdala. Neuropharmacology. 172: 108129. PMID 32418906 DOI: 10.1016/J.Neuropharm.2020.108129  0.851
2019 McCool BA, McGinnis MM. Adolescent Vulnerability to Alcohol Use Disorder: Neurophysiological Mechanisms from Preclinical Studies. Handbook of Experimental Pharmacology. PMID 31595414 DOI: 10.1007/164_2019_296  0.79
2019 McGinnis MM, Parrish BC, Chappell AM, Alexander NJ, McCool BA. Chronic Ethanol Differentially Modulates Glutamate Release from Dorsal and Ventral Prefrontal Cortical Inputs onto Rat Basolateral Amygdala Principal Neurons. Eneuro. PMID 31548367 DOI: 10.1523/ENEURO.0132-19.2019  0.833
2019 Luessen DJ, Sun H, McGinnis MM, Hagstrom M, Marrs G, McCool BA, Chen R. Acute ethanol exposure reduces serotonin receptor 1A internalization by increasing ubiquitination and degradation of β-arrestin2. The Journal of Biological Chemistry. PMID 31366729 DOI: 10.1074/Jbc.Ra118.006583  0.807
2019 Frost ME, Peterson VL, Bird CW, McCool B, Hamilton DA. Effects of Ethanol Exposure and Withdrawal on Neuronal Morphology in the Agranular Insular and Prelimbic Cortices: Relationship with Withdrawal-Related Structural Plasticity in the Nucleus Accumbens. Brain Sciences. 9. PMID 31357611 DOI: 10.3390/Brainsci9080180  0.505
2018 Karkhanis AN, Leach AC, Yorgason JT, Uneri A, Barth S, Niere F, Alexander NJ, Weiner JL, McCool BA, Raab-Graham KF, Ferris MJ, Jones SR. Chronic social isolation stress during peri-adolescence alters presynaptic dopamine terminal dynamics via augmentation in accumbal dopamine availability. Acs Chemical Neuroscience. PMID 30284806 DOI: 10.1021/Acschemneuro.8B00360  0.319
2018 Alexander NJ, Rau AR, Jimenez VA, Daunais JB, Grant KA, McCool BA. SNARE Complex-associated Proteins in the Lateral Amygdala of Macaca mullatta Following Long-term Ethanol Drinking. Alcoholism, Clinical and Experimental Research. PMID 29944190 DOI: 10.1111/Acer.13821  0.523
2017 Morales M, McGinnis MM, Robinson SL, Chappell AM, McCool BA. Chronic Intermittent Ethanol Exposure Modulation of Glutamatergic Neurotransmission in Rat Lateral/Basolateral Amygdala is Duration-, Input-, and Sex-Dependent. Neuroscience. PMID 29237566 DOI: 10.1016/J.Neuroscience.2017.12.005  0.841
2017 Gioia DA, Alexander N, McCool BA. Ethanol Mediated Inhibition of Synaptic Vesicle Recycling at Amygdala Glutamate Synapses Is Dependent upon Munc13-2. Frontiers in Neuroscience. 11: 424. PMID 28785200 DOI: 10.3389/fnins.2017.00424  0.759
2017 Jluessen D, Sun H, McGinnis MM, McCool BA, Chen R. Chronic intermittent ethanol exposure selectively alters the expression of Gα subunit isoforms and RGS subtypes in rat prefrontal cortex. Brain Research. PMID 28736108 DOI: 10.1016/J.Brainres.2017.07.014  0.808
2017 Gioia DA, McCool BA. Strain-Dependent Effects of Acute Alcohol on Synaptic Vesicle Recycling and Post-Tetanic Potentiation In Medial Glutamate Inputs to the Mouse Basolateral Amygdala. Alcoholism, Clinical and Experimental Research. PMID 28118494 DOI: 10.1111/acer.13343  0.726
2017 McGinnis MM, Morales MM, Alexander NJ, McCool BA. Effects of chronic ethanol exposure and withdrawal on glutamatergic signaling at two afferent projections into the rat lateral/basolateral amygdala Alcohol. 60: 232. DOI: 10.1016/J.Alcohol.2017.02.307  0.829
2016 Gioia DA, Alexander NJ, McCool BA. Differential Expression of Munc13-2 Produces Unique Synaptic Phenotypes in the Basolateral Amygdala of C57BL/6J and DBA/2J Mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 10964-10977. PMID 27798178 DOI: 10.1523/JNEUROSCI.1785-16.2016  0.639
2015 Robinson SL, Alexander NJ, Bluett RJ, Patel S, McCool BA. Acute and Chronic Ethanol Exposure Differentially Regulate CB1 Receptor Function at Glutamatergic Synapses in the Rat Basolateral Amygdala. Neuropharmacology. PMID 26707595 DOI: 10.1016/J.Neuropharm.2015.12.005  0.711
2015 Rose JH, Karkhanis A, Chen R, Gioia D, Lopez MF, Becker HC, McCool BA, Jones SR. Supersensitive kappa opioid receptors promotes ethanol withdrawal-related behaviors and reduced dopamine signaling in the nucleus accumbens. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). PMID 26625893 DOI: 10.1093/Ijnp/Pyv127  0.706
2015 Morales M, McGinnis MM, McCool BA. Chronic ethanol exposure increases voluntary home cage intake in adult male, but not female, Long-Evans rats. Pharmacology, Biochemistry, and Behavior. 139: 67-76. PMID 26515190 DOI: 10.1016/J.Pbb.2015.10.016  0.825
2015 Robinson SL, McCool BA. Microstructural analysis of rat ethanol and water drinking patterns using a modified operant self-administration model. Physiology & Behavior. 149: 119-130. PMID 26037631 DOI: 10.1016/j.physbeh.2015.05.034  0.626
2015 Karkhanis AN, Alexander NJ, McCool BA, Weiner JL, Jones SR. Chronic social isolation during adolescence augments catecholamine response to acute ethanol in the basolateral amygdala. Synapse (New York, N.Y.). 69: 385-95. PMID 25963724 DOI: 10.1002/Syn.21826  0.463
2015 Peterson VL, McCool BA, Hamilton DA. Effects of ethanol exposure and withdrawal on dendritic morphology and spine density in the nucleus accumbens core and shell. Brain Research. 1594: 125-35. PMID 25452024 DOI: 10.1016/J.Brainres.2014.10.036  0.494
2014 Karkhanis AN, Locke JL, McCool BA, Weiner JL, Jones SR. Social isolation rearing increases nucleus accumbens dopamine and norepinephrine responses to acute ethanol in adulthood. Alcoholism, Clinical and Experimental Research. 38: 2770-9. PMID 25421514 DOI: 10.1111/Acer.12555  0.433
2014 McCool BA, Christian DT, Fetzer JA, Chappell AM. Lateral/basolateral amygdala serotonin type-2 receptors modulate operant self-administration of a sweetened ethanol solution via inhibition of principal neuron activity. Frontiers in Integrative Neuroscience. 8: 5. PMID 24523680 DOI: 10.3389/fnint.2014.00005  0.758
2013 Abrahao KP, Ariwodola OJ, Butler TR, Rau AR, Skelly MJ, Carter E, Alexander NP, McCool BA, Souza-Formigoni ML, Weiner JL. Locomotor sensitization to ethanol impairs NMDA receptor-dependent synaptic plasticity in the nucleus accumbens and increases ethanol self-administration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 4834-42. PMID 23486954 DOI: 10.1523/Jneurosci.5839-11.2013  0.833
2013 Christian DT, Alexander NJ, Diaz MR, McCool BA. Thalamic glutamatergic afferents into the rat basolateral amygdala exhibit increased presynaptic glutamate function following withdrawal from chronic intermittent ethanol. Neuropharmacology. 65: 134-42. PMID 22982568 DOI: 10.1016/j.neuropharm.2012.09.004  0.854
2013 Chappell AM, Carter E, McCool BA, Weiner JL. Adolescent rearing conditions influence the relationship between initial anxiety-like behavior and ethanol drinking in male Long Evans rats. Alcoholism, Clinical and Experimental Research. 37: E394-403. PMID 22924742 DOI: 10.1111/J.1530-0277.2012.01926.X  0.373
2012 Christian DT, Alexander NJ, Diaz MR, Robinson S, McCool BA. Chronic intermittent ethanol and withdrawal differentially modulate basolateral amygdala AMPA-type glutamate receptor function and trafficking. Neuropharmacology. 62: 2430-9. PMID 22387532 DOI: 10.1016/J.Neuropharm.2012.02.017  0.837
2011 Diaz MR, Chappell AM, Christian DT, Anderson NJ, McCool BA. Dopamine D3-like receptors modulate anxiety-like behavior and regulate GABAergic transmission in the rat lateral/basolateral amygdala. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 1090-103. PMID 21270771 DOI: 10.1038/npp.2010.246  0.801
2011 Diaz MR, Christian DT, Anderson NJ, McCool BA. Chronic ethanol and withdrawal differentially modulate lateral/basolateral amygdala paracapsular and local GABAergic synapses. The Journal of Pharmacology and Experimental Therapeutics. 337: 162-70. PMID 21209156 DOI: 10.1124/jpet.110.177121  0.849
2010 McCool BA, Christian DT, Diaz MR, Läck AK. Glutamate plasticity in the drunken amygdala: the making of an anxious synapse. International Review of Neurobiology. 91: 205-33. PMID 20813244 DOI: 10.1016/S0074-7742(10)91007-6  0.809
2009 Silberman Y, Bajo M, Chappell AM, Christian DT, Cruz M, Diaz MR, Kash T, Lack AK, Messing RO, Siggins GR, Winder D, Roberto M, McCool BA, Weiner JL. Neurobiological mechanisms contributing to alcohol-stress-anxiety interactions. Alcohol (Fayetteville, N.Y.). 43: 509-19. PMID 19913194 DOI: 10.1016/J.Alcohol.2009.01.002  0.822
2009 Läck AK, Christian DT, Diaz MR, McCool BA. Chronic ethanol and withdrawal effects on kainate receptor-mediated excitatory neurotransmission in the rat basolateral amygdala. Alcohol (Fayetteville, N.Y.). 43: 25-33. PMID 19185207 DOI: 10.1016/j.alcohol.2008.11.002  0.835
2008 Läck AK, Ariwodola OJ, Chappell AM, Weiner JL, McCool BA. Ethanol inhibition of kainate receptor-mediated excitatory neurotransmission in the rat basolateral nucleus of the amygdala. Neuropharmacology. 55: 661-8. PMID 18617194 DOI: 10.1016/J.Neuropharm.2008.05.026  0.852
2007 Läck AK, Diaz MR, Chappell A, DuBois DW, McCool BA. Chronic ethanol and withdrawal differentially modulate pre- and postsynaptic function at glutamatergic synapses in rat basolateral amygdala. Journal of Neurophysiology. 98: 3185-96. PMID 17898152 DOI: 10.1152/jn.00189.2007  0.842
2007 Budygin EA, Oleson EB, Mathews TA, Läck AK, Diaz MR, McCool BA, Jones SR. Effects of chronic alcohol exposure on dopamine uptake in rat nucleus accumbens and caudate putamen. Psychopharmacology. 193: 495-501. PMID 17492432 DOI: 10.1007/S00213-007-0812-1  0.789
2007 Anderson NJ, Daunais JB, Friedman DP, Grant KA, McCool BA. Long-term ethanol self-administration by the nonhuman primate, Macaca fascicularis, decreases the benzodiazepine sensitivity of amygdala GABA(A) receptors. Alcoholism, Clinical and Experimental Research. 31: 1061-70. PMID 17428292 DOI: 10.1111/J.1530-0277.2007.00394.X  0.548
2006 Hemby SE, O'connor JA, Acosta G, Floyd D, Anderson N, McCool BA, Friedman D, Grant KA. Ethanol-induced regulation of GABA-A subunit mRNAs in prefrontal fields of cynomolgus monkeys. Alcoholism, Clinical and Experimental Research. 30: 1978-85. PMID 17117962 DOI: 10.1111/J.1530-0277.2006.00254.X  0.423
2006 DuBois DW, Perlegas A, Floyd DW, Weiner JL, McCool BA. Distinct functional characteristics of the lateral/basolateral amygdala GABAergic system in C57BL/6J and DBA/2J mice. The Journal of Pharmacology and Experimental Therapeutics. 318: 629-40. PMID 16651400 DOI: 10.1124/jpet.105.100552  0.633
2005 Läck AK, Floyd DW, McCool BA. Chronic ethanol ingestion modulates proanxiety factors expressed in rat central amygdala. Alcohol (Fayetteville, N.Y.). 36: 83-90. PMID 16396741 DOI: 10.1016/j.alcohol.2005.07.004  0.846
2004 Farroni JS, McCool BA. Extrinsic factors regulate partial agonist efficacy of strychnine-sensitive glycine receptors. Bmc Pharmacology. 4: 16. PMID 15301692 DOI: 10.1186/1471-2210-4-16  0.758
2004 Floyd DW, Friedman DP, Daunais JB, Pierre PJ, Grant KA, McCool BA. Long-term ethanol self-administration by cynomolgus macaques alters the pharmacology and expression of GABAA receptors in basolateral amygdala. The Journal of Pharmacology and Experimental Therapeutics. 311: 1071-9. PMID 15280440 DOI: 10.1124/Jpet.104.072025  0.522
2004 Ariwodola OJ, Davenport AT, Grant KA, Daunais JB, Friedman DP, McCool BA, Weiner JL. THE EFFECT OF LONG-TERM VOLUNTARY ETHANOL CONSUMPTION ON THE GABAA RECEPTOR SYSTEM IN THE MONKEY CNS. Alcoholism: Clinical & Experimental Research. 28: 73A. DOI: 10.1097/00000374-200408002-00401  0.476
2004 Ariwodola OJ, Bryant V, Chappel A, Legg B, McCool BA, Valenzuela CF, Weiner JL. ETHANOL, ANXIETY, AND AMYGDALA KAINATE RECEPTORS. Alcoholism: Clinical & Experimental Research. 28: 41A. DOI: 10.1097/00000374-200408002-00204  0.706
2003 Floyd DW, Jung KY, McCool BA. Chronic ethanol ingestion facilitates N-methyl-D-aspartate receptor function and expression in rat lateral/basolateral amygdala neurons. The Journal of Pharmacology and Experimental Therapeutics. 307: 1020-9. PMID 14534353 DOI: 10.1124/jpet.103.057505  0.571
2003 Botting SK, Frye GD, Pulido MD, McCool BA. Effects of chronic alcohol ingestion on rat lateral/basolateral amygdala ligand-gated chloride channels. Annals of the New York Academy of Sciences. 985: 479-80. PMID 12724181 DOI: 10.1111/J.1749-6632.2003.Tb07104.X  0.852
2003 McCool BA, Frye GD, Pulido MD, Botting SK. Effects of chronic ethanol consumption on rat GABA(A) and strychnine-sensitive glycine receptors expressed by lateral/basolateral amygdala neurons. Brain Research. 963: 165-77. PMID 12560122 DOI: 10.1016/S0006-8993(02)03966-5  0.845
2002 Hsiao SH, Parrish AR, Nahm SS, Abbott LC, McCool BA, Frye GD. Effects of early postnatal ethanol intubation on GABAergic synaptic proteins. Brain Research. Developmental Brain Research. 138: 177-85. PMID 12354645 DOI: 10.1016/S0165-3806(02)00470-4  0.677
2001 McCool BA, Farroni JS. Subunit composition of strychnine-sensitive glycine receptors expressed by adult rat basolateral amygdala neurons. The European Journal of Neuroscience. 14: 1082-90. PMID 11683900 DOI: 10.1046/j.0953-816X.2001.01730.x  0.758
2001 McCool BA, Farroni JS. A1 adenosine receptors inhibit multiple voltage-gated Ca2+ channel subtypes in acutely isolated rat basolateral amygdala neurons. British Journal of Pharmacology. 132: 879-88. PMID 11181429 DOI: 10.1038/sj.bjp.0703884  0.758
2000 McCool BA, Botting SK. Characterization of strychnine-sensitive glycine receptors in acutely isolated adult rat basolateral amygdala neurons. Brain Research. 859: 341-51. PMID 10719083 DOI: 10.1016/S0006-8993(00)02026-6  0.75
1998 McCool BA, Pin JP, Harpold MM, Brust PF, Stauderman KA, Lovinger DM. Rat group I metabotropic glutamate receptors inhibit neuronal Ca2+ channels via multiple signal transduction pathways in HEK 293 cells. Journal of Neurophysiology. 79: 379-91. PMID 9425207 DOI: 10.1152/Jn.1998.79.1.379  0.507
1997 McCool BA, Harpold MM, Stauderman KA, Brust PF, Lovinger DM. Relative contributions of G protein, channel, and receptor to voltage-dependent inhibition of neuronal N-type and P/Q-type calcium channels in HEK 293 cell lines. Neuroscience Letters. 239: 89-92. PMID 9469663 DOI: 10.1016/S0304-3940(97)00893-8  0.507
1997 Lakhlani PP, MacMillan LB, Guo TZ, McCool BA, Lovinger DM, Maze M, Limbird LE. Substitution of a mutant alpha2a-adrenergic receptor via "hit and run" gene targeting reveals the role of this subtype in sedative, analgesic, and anesthetic-sparing responses in vivo. Proceedings of the National Academy of Sciences of the United States of America. 94: 9950-5. PMID 9275232 DOI: 10.1073/pnas.94.18.9950  0.54
1996 McCool BA, Pin JP, Brust PF, Harpold MM, Lovinger DM. Functional coupling of rat group II metabotropic glutamate receptors to an omega-conotoxin GVIA-sensitive calcium channel in human embryonic kidney 293 cells. Molecular Pharmacology. 50: 912-22. PMID 8863837  0.447
1996 McCool B, Pin J, Harpold M, Brust P, Slaudennan K, Lovinger D. Rat group I mGluRs inhibit calcium channels via multiple, convergent signal transduction pathways Neuropharmacology. 35: A20. DOI: 10.1016/0028-3908(96)84724-1  0.507
1995 Singleton CK, Pekovich SR, McCool BA, Martin PR. The thiamine-dependent hysteretic behavior of human transketolase: implications for thiamine deficiency. The Journal of Nutrition. 125: 189-94. PMID 7861245 DOI: 10.1093/Jn/125.2.189  0.51
1995 Lovinger DM, McCool BA. Metabotropic glutamate receptor-mediated presynaptic depression at corticostriatal synapses involves mGLuR2 or 3. Journal of Neurophysiology. 73: 1076-83. PMID 7608756 DOI: 10.1152/Jn.1995.73.3.1076  0.507
1995 Martin PR, McCool BA, Singleton CK. Molecular genetics of transketolase in the pathogenesis of the Wernicke-Korsakoff syndrome. Metabolic Brain Disease. 10: 45-55. PMID 7596328 DOI: 10.1007/BF01991782  0.538
1995 McCool BA, Lovinger DM. Ifenprodil inhibition of the 5-hydroxytryptamine3 receptor. Neuropharmacology. 34: 621-9. PMID 7566498 DOI: 10.1016/0028-3908(95)00030-A  0.507
1995 Ikeda SR, Lovinger DM, McCool BA, Lewis DL. Heterologous expression of metabotropic glutamate receptors in adult rat sympathetic neurons: subtype-specific coupling to ion channels. Neuron. 14: 1029-38. PMID 7538309 DOI: 10.1016/0896-6273(95)90341-0  0.534
1994 Martin PR, Pekovich SR, McCool BA, Whetsell WO, Singleton CK. Thiamine utilization in the pathogenesis of alcohol-induced brain damage. Alcohol and Alcoholism (Oxford, Oxfordshire). Supplement. 2: 273-9. PMID 8974347  0.517
1993 Martin PR, McCool BA, Singleton CK. Genetic sensitivity to thiamine deficiency and development of alcoholic organic brain disease. Alcoholism, Clinical and Experimental Research. 17: 31-7. PMID 8452206 DOI: 10.1111/J.1530-0277.1993.Tb00722.X  0.574
1993 McCool BA, Plonk SG, Martin PR, Singleton CK. Cloning of human transketolase cDNAs and comparison of the nucleotide sequence of the coding region in Wernicke-Korsakoff and non-Wernicke-Korsakoff individuals. The Journal of Biological Chemistry. 268: 1397-404. PMID 8419340  0.446
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