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Magid Abou-Gharbia - Publications

Affiliations: 
Pharmaceutical Sciences Temple University, Philadelphia, PA, United States 
Area:
Pharmacology, Inorganic Chemistry, Pharmacy
Website:
https://moulder.temple.edu/about-us/director
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43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Hewlett ED, Melenski E, Qiu FV, Leung HT, Jacobson M, Qiu F, Abou-Gharbia M, Childers W. Facile synthesis of the glucosylceramide synthase inhibitor GZ667161 Tetrahedron Letters. 61: 152352. DOI: 10.1016/J.Tetlet.2020.152352  0.338
2019 Childers W, Fan R, Martinez R, Colussi DJ, Melenski E, Liu Y, Gordon J, Abou-Gharbia M, Jacobson MA. Novel compounds that reverse the disease phenotype in Type 2 Gaucher disease patient-derived cells. Bioorganic & Medicinal Chemistry Letters. 126806. PMID 31757667 DOI: 10.1016/J.Bmcl.2019.126806  0.3
2018 Blass BE, Iyer P, Abou-Gharbia M, Childers WE, Gordon JC, Ramanjulu M, Morton G, Arumugam P, Boruwa J, Ellingboe J, Mitra S, Reddy Nimmareddy R, Paliwal S, Rajasekhar J, Shivakumar S, et al. Design and synthesis of functionalized piperazin-1yl-(E)-stilbenes as inhibitors of 17α-hydroxylase-C17,20-lyase (Cyp17). Bioorganic & Medicinal Chemistry Letters. PMID 29803730 DOI: 10.1016/J.Bmcl.2018.05.040  0.373
2018 Lounsbury N, Eidem T, Colquhoun J, Mateo G, Abou-Gharbia M, Dunman PM, Childers WE. Novel inhibitors of Staphylococcus aureus RnpA that synergize with mupirocin. Bioorganic & Medicinal Chemistry Letters. PMID 29463447 DOI: 10.1016/J.Bmcl.2018.01.022  0.301
2017 Al-Ashmawy AAK, Ragab FA, Elokely KM, Anwar MM, Perez-Leal O, Rico MC, Gordon J, Bichenkov E, Mateo G, Kassem EMM, Hegazy GH, Abou-Gharbia M, Childers W. Design, synthesis and SAR of new-di-substituted pyridopyrimidines as ATP-competitive dual PI3Kα/mTOR inhibitors. Bioorganic & Medicinal Chemistry Letters. PMID 28571824 DOI: 10.1016/J.Bmcl.2017.05.044  0.322
2017 Zhang H, Raynal NJ-, Sato T, Okamoto Y, Garriga J, Garcia B, Morton G, Childers W, Jacobson MA, Baylin SB, Graña X, Abou-Gharbia M, Issa JJ. Abstract 5064: Identifying novel potential epigenetic anti-cancer drugs from natural compounds using a phenotypic-based screening Cancer Research. 77: 5064-5064. DOI: 10.1158/1538-7445.Am2017-5064  0.304
2016 Zhang H, Raynal NJ-, Sato T, Okamoto Y, Garcia B, Morton G, Childers W, Jacobson MA, Baylin SB, Abou-Gharbia M, Issa JJ. Abstract B50: A phenotypic screen to identify novel potential epigenetic anticancer drugs from natural compounds Cancer Research. 76. DOI: 10.1158/1538-7445.Chromepi15-B50  0.306
2016 Zhang H, Raynal NJ-, Sato T, Okamoto Y, Garriga J, Morton G, Childers W, Jacobson MA, Baylin SB, Graña X, Abou-Gharbia M, Issa JJ. Abstract 4701: A phenotypic cell-based screen to identify novel potential epigenetic anti-cancer drugs from natural compounds Cancer Research. 76: 4701-4701. DOI: 10.1158/1538-7445.Am2016-4701  0.311
2015 Zhang H, Raynal N, Sato T, Okamoto Y, Henry R, Andrews AJ, Morton G, Childers W, Jacobson MA, Abou-Gharbia M, Issa JJ. Abstract 3519: A phenotypic screen to discover novel epigenetic anticancer drugs from natural compounds Cancer Research. 75: 3519-3519. DOI: 10.1158/1538-7445.Am2015-3519  0.312
2014 Butts A, Koselny K, Chabrier-Roselló Y, Semighini CP, Brown JC, Wang X, Annadurai S, DiDone L, Tabroff J, Childers WE, Abou-Gharbia M, Wellington M, Cardenas ME, Madhani HD, Heitman J, et al. Estrogen receptor antagonists are anti-cryptococcal agents that directly bind EF hand proteins and synergize with fluconazole in vivo. Mbio. 5: e00765-13. PMID 24520056 DOI: 10.1128/Mbio.00765-13  0.308
2014 Munagala S, Sirasani G, Kokkonda P, Phadke M, Krynetskaia N, Lu P, Sharom FJ, Chaudhury S, Abdulhameed MD, Tawa G, Wallqvist A, Martinez R, Childers W, Abou-Gharbia M, Krynetskiy E, et al. Synthesis and evaluation of Strychnos alkaloids as MDR reversal agents for cancer cell eradication. Bioorganic & Medicinal Chemistry. 22: 1148-55. PMID 24405813 DOI: 10.1016/J.Bmc.2013.12.022  0.326
2014 Perez-Leal O, Abou-Gharbia M, Gordon J, Childers WE, Merali S. A novel assay platform for the detection of translation modulators of spermidine/spermine acetyltransferase. Current Pharmaceutical Design. 20: 245-52. PMID 23701549 DOI: 10.2174/13816128113199990035  0.313
2012 Annadurai S, Martinez R, Canney DJ, Eidem T, Dunman PM, Abou-Gharbia M. Design and synthesis of 2-aminothiazole based antimicrobials targeting MRSA. Bioorganic & Medicinal Chemistry Letters. 22: 7719-25. PMID 23116888 DOI: 10.1016/J.Bmcl.2012.09.095  0.324
2011 Ghidu VP, Ilies MA, Cullen T, Pollet R, Abou-Gharbia M. A new and efficient synthetic route for the anxiolytic agent CL285032. Bioorganic & Medicinal Chemistry Letters. 21: 259-61. PMID 21095124 DOI: 10.1016/J.Bmcl.2010.11.017  0.302
2004 Elokdah H, Abou-Gharbia M, Hennan JK, McFarlane G, Mugford CP, Krishnamurthy G, Crandall DL. Tiplaxtinin, a novel, orally efficacious inhibitor of plasminogen activator inhibitor-1: Design, synthesis, and preclinical characterization Journal of Medicinal Chemistry. 47: 3491-3494. PMID 15214776 DOI: 10.1021/Jm049766Q  0.307
2004 Elokdah H, Sulkowski TS, Abou-Gharbia M, Butera JA, Chai SY, McFarlane GR, McKean ML, Babiak JL, Adelman SJ, Quinet EM. Design, synthesis, and biological evaluation of thio-containing compounds with serum HDL-cholesterol-elevating properties. Journal of Medicinal Chemistry. 47: 681-95. PMID 14736248 DOI: 10.1021/Jm030219Z  0.305
1998 Mewshaw RE, Marquis KL, Shi X, McGaughey G, Stack G, Webb MB, Abou-Gharbia M, Wasik T, Scerni R, Spangler T, Brennan JA, Mazandarani H, Coupet J, Andree TH. New generation dopaminergic agents 4. Exploiting the 2-methyl chroman scaffold. Synthesis and evaluation of two novel series of 2-(aminomethyl)- 3,4,7,9-tetrahydro-2H-pyrano[2,3-e]indole and indol-8-one derivatives Tetrahedron. 54: 7081-7108. DOI: 10.1016/S0040-4020(98)00349-4  0.328
1995 Abou-Gharbia M, Moyer JA, Nielsen ST, Webb M, Patel U. New antihistamines: substituted piperazine and piperidine derivatives as novel H1-antagonists. Journal of Medicinal Chemistry. 38: 4026-32. PMID 7562938 DOI: 10.1021/Jm00020A018  0.306
1989 Abou-Gharbia M, Moyer JA, Patel U, Webb M, Schiehser G, Andree T, Haskins JT. Synthesis and structure-activity relationship of substituted tetrahydro- and hexahydro-1,2-benzisothiazol-3-one 1,1-dioxides and thiadiazinones: potential anxiolytic agents. Journal of Medicinal Chemistry. 32: 1024-33. PMID 2565399 DOI: 10.1021/Jm00125A016  0.328
1988 Abou-Gharbia M, Patel UR, Webb MB, Moyer JA, Andree TH, Muth EA. Polycyclic aryl- and heteroarylpiperazinyl imides as 5-HT1A receptor ligands and potential anxiolytic agents: synthesis and structure-activity relationship studies. Journal of Medicinal Chemistry. 31: 1382-92. PMID 2898533 DOI: 10.1021/Jm00402A023  0.317
1987 Abou-Gharbia M, Patel UR, Webb MB, Moyer JA, Andree TH, Muth EA. Antipsychotic activity of substituted gamma-carbolines. Journal of Medicinal Chemistry. 30: 1818-23. PMID 2888898 DOI: 10.1021/Jm00393A023  0.306
1987 Abou-Gharbia M, Patel UR, Moyer JA, Muth EA. Psychotropic agents: synthesis and antipsychotic activity of substituted beta-carbolines. Journal of Medicinal Chemistry. 30: 1100-5. PMID 2884314 DOI: 10.1021/Jm00389A022  0.302
1986 Abou-Gharbia M. Synthesis of Novel Hexahydroquinolines and Hexahydroacridines Heterocycles. 24: 1347-1353. DOI: 10.1002/Chin.198641240  0.366
1985 Abou-Gharbia M, Hoffman BR. A New Synthesis Of 2-Bromo-1-(9-Phenanthryl)Ethane Organic Preparations and Procedures International. 16: 195-198. DOI: 10.1080/00304948509355500  0.346
1984 Abou-Gharbia MA, Joullié MM. Structural elucidation of isomeric Oxazolidinones and Isoxazolidinones by13C N. M. R. Journal FüR Praktische Chemie. 326: 1008-1010. DOI: 10.1002/prac.19843260622  0.371
1983 Ketcha DM, Abou-Gharbia M, Smith FX, Swern D. Reaction of N-acylsulfilimines with diphenyl ketene. A new synthesis of 2-oxazolin-4-ones Tetrahedron Letters. 24: 2811-2814. DOI: 10.1016/S0040-4039(00)88030-2  0.351
1981 Abou-Gharbia MA, Terwilliger DT, Joullie MM, Srivastava RM. Mass spectra of nitrones. Electron impact mass spectra of fluorenone nitrones Journal of Chemical & Engineering Data. 26: 216-218. DOI: 10.1021/je00024a038  0.35
1981 ABOU-GHARBIA MA, TERWILLIGER DT, JOULLIE MM, SRIVASTAVA RM. ChemInform Abstract: MASS SPECTRA OF NITRONES. ELECTRON IMPACT MASS SPECTRA OF FLUORENONE NITRONES Chemischer Informationsdienst. 12. DOI: 10.1002/chin.198129068  0.359
1980 Abou-Gharbia M, Joullie M. Additions and Corrections - Cyclo-additions of Ketenes with N-Fluorenylidenealklamine and -arylamine Oxides. Synthesis of Spirooxazolidinones and Spiroisoxazolidinones The Journal of Organic Chemistry. 45: 5432-5432. DOI: 10.1021/Jo01314A605  0.496
1980 Abou-Gharbia MA, Joullié MM. The mass spectra of fluorenone nitrones Organic Mass Spectrometry. 15: 489-490. DOI: 10.1002/oms.1210150915  0.346
1980 ABOU-GHARBIA MA, JOULLIE MM. ChemInform Abstract: REACTION OF TERT-BUTYLCYANOKETENE WITH 2′-CYCLOHEXYLSPIRO(FLUORENE-9,3′-OXAZIRIDINE) Chemischer Informationsdienst. 11. DOI: 10.1002/chin.198025210  0.427
1979 Abou-Gharbia MA, Joullié MM. AN IMPROVED SYNTHESIS OF FLUORENONE METHYLNITRONE Organic Preparations and Procedures International. 11: 95-96. DOI: 10.1080/00304947909354848  0.449
1979 Abou-Gharbia MA, Joullie MM. Cycloaddition of ketenes with N-fluorenylidenealkylamine and -arylamine oxides. Synthesis of spirooxazolidinones and spiroisoxazolidinones The Journal of Organic Chemistry. 44: 2961-2966. DOI: 10.1021/jo01331a002  0.437
1979 ABOU-GHARBIA MA, JOULLIE MM. ChemInform Abstract: SYNTHESIS OF SPIROFLUORENES VIA KETENE ADDUCTS Chemischer Informationsdienst. 10. DOI: 10.1002/chin.197948114  0.481
1979 ABOU-GHARBIA MA, JOULLIE MM. ChemInform Abstract: REACTIONS OF NITRONES WITH KETENES Chemischer Informationsdienst. 10. DOI: 10.1002/chin.197944370  0.393
1979 ABOU-GHARBIA MA, JOULLIE MM. ChemInform Abstract: AN IMPROVED SYNTHESIS OF FLUORENONE METHYLNITRONE Chemischer Informationsdienst. 10. DOI: 10.1002/chin.197942198  0.462
1978 Abou-Gharbia MA, Su TT, Joullié MM. Synthesis of spirofluorenes of biological interest. Journal of Pharmaceutical Sciences. 67: 953-6. PMID 660513 DOI: 10.1002/jps.2600670721  0.5
1978 ABOU-GHARBIA MA, SU TT, JOULLIE MM. ChemInform Abstract: SYNTHESIS OF SPIROFLUORENES OF BIOLOGICAL INTEREST Chemischer Informationsdienst. 9. DOI: 10.1002/chin.197847160  0.475
1978 ABOU-GHARBIA MA, JOULLIE MM, MIURA I. ChemInform Abstract: THE REGIOSELECTIVITY OF THE CYCLOADDITIONS OF KETENES WITH N-ALKYL- AND N-ARYLNITRONES Chemischer Informationsdienst. 9. DOI: 10.1002/chin.197837222  0.414
1978 ABOU-GHARBIA M, JOULLIE MM. ChemInform Abstract: SYNTHESIS AND HYDROLYSIS OF FLUORENE-9-SPIRO-2′-(N-ARYL-3′,3′-DICHLOROAZIRIDINES) Chemischer Informationsdienst. 9. DOI: 10.1002/Chin.197816166  0.53
1977 Abou-Gharbia M, Joullié MM. Synthesis and hydrolysis of fluorene-9-spiro-2'-(N-aryl-3' ,3'-dichloroaziridines) Journal of Pharmaceutical Sciences. 66: 1653-5. PMID 915756 DOI: 10.1002/Jps.2600661146  0.523
1977 ABOU-GHARBIA M, JOULLIÉ MM. A New Synthesis of Nitrones Synthesis. 1977: 318-320. DOI: 10.1055/S-1977-24378  0.513
1977 ABOU-GHARBIA M, JOULLIE MM. ChemInform Abstract: A NEW SYNTHESIS OF NITRONES Chemischer Informationsdienst. 8: no-no. DOI: 10.1002/chin.197735173  0.469
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