Year |
Citation |
Score |
2020 |
Hewlett ED, Melenski E, Qiu FV, Leung HT, Jacobson M, Qiu F, Abou-Gharbia M, Childers W. Facile synthesis of the glucosylceramide synthase inhibitor GZ667161 Tetrahedron Letters. 61: 152352. DOI: 10.1016/J.Tetlet.2020.152352 |
0.338 |
|
2019 |
Childers W, Fan R, Martinez R, Colussi DJ, Melenski E, Liu Y, Gordon J, Abou-Gharbia M, Jacobson MA. Novel compounds that reverse the disease phenotype in Type 2 Gaucher disease patient-derived cells. Bioorganic & Medicinal Chemistry Letters. 126806. PMID 31757667 DOI: 10.1016/J.Bmcl.2019.126806 |
0.3 |
|
2018 |
Blass BE, Iyer P, Abou-Gharbia M, Childers WE, Gordon JC, Ramanjulu M, Morton G, Arumugam P, Boruwa J, Ellingboe J, Mitra S, Reddy Nimmareddy R, Paliwal S, Rajasekhar J, Shivakumar S, et al. Design and synthesis of functionalized piperazin-1yl-(E)-stilbenes as inhibitors of 17α-hydroxylase-C17,20-lyase (Cyp17). Bioorganic & Medicinal Chemistry Letters. PMID 29803730 DOI: 10.1016/J.Bmcl.2018.05.040 |
0.373 |
|
2018 |
Lounsbury N, Eidem T, Colquhoun J, Mateo G, Abou-Gharbia M, Dunman PM, Childers WE. Novel inhibitors of Staphylococcus aureus RnpA that synergize with mupirocin. Bioorganic & Medicinal Chemistry Letters. PMID 29463447 DOI: 10.1016/J.Bmcl.2018.01.022 |
0.301 |
|
2017 |
Al-Ashmawy AAK, Ragab FA, Elokely KM, Anwar MM, Perez-Leal O, Rico MC, Gordon J, Bichenkov E, Mateo G, Kassem EMM, Hegazy GH, Abou-Gharbia M, Childers W. Design, synthesis and SAR of new-di-substituted pyridopyrimidines as ATP-competitive dual PI3Kα/mTOR inhibitors. Bioorganic & Medicinal Chemistry Letters. PMID 28571824 DOI: 10.1016/J.Bmcl.2017.05.044 |
0.322 |
|
2017 |
Zhang H, Raynal NJ-, Sato T, Okamoto Y, Garriga J, Garcia B, Morton G, Childers W, Jacobson MA, Baylin SB, Graña X, Abou-Gharbia M, Issa JJ. Abstract 5064: Identifying novel potential epigenetic anti-cancer drugs from natural compounds using a phenotypic-based screening Cancer Research. 77: 5064-5064. DOI: 10.1158/1538-7445.Am2017-5064 |
0.304 |
|
2016 |
Zhang H, Raynal NJ-, Sato T, Okamoto Y, Garcia B, Morton G, Childers W, Jacobson MA, Baylin SB, Abou-Gharbia M, Issa JJ. Abstract B50: A phenotypic screen to identify novel potential epigenetic anticancer drugs from natural compounds Cancer Research. 76. DOI: 10.1158/1538-7445.Chromepi15-B50 |
0.306 |
|
2016 |
Zhang H, Raynal NJ-, Sato T, Okamoto Y, Garriga J, Morton G, Childers W, Jacobson MA, Baylin SB, Graña X, Abou-Gharbia M, Issa JJ. Abstract 4701: A phenotypic cell-based screen to identify novel potential epigenetic anti-cancer drugs from natural compounds Cancer Research. 76: 4701-4701. DOI: 10.1158/1538-7445.Am2016-4701 |
0.311 |
|
2015 |
Zhang H, Raynal N, Sato T, Okamoto Y, Henry R, Andrews AJ, Morton G, Childers W, Jacobson MA, Abou-Gharbia M, Issa JJ. Abstract 3519: A phenotypic screen to discover novel epigenetic anticancer drugs from natural compounds Cancer Research. 75: 3519-3519. DOI: 10.1158/1538-7445.Am2015-3519 |
0.312 |
|
2014 |
Butts A, Koselny K, Chabrier-Roselló Y, Semighini CP, Brown JC, Wang X, Annadurai S, DiDone L, Tabroff J, Childers WE, Abou-Gharbia M, Wellington M, Cardenas ME, Madhani HD, Heitman J, et al. Estrogen receptor antagonists are anti-cryptococcal agents that directly bind EF hand proteins and synergize with fluconazole in vivo. Mbio. 5: e00765-13. PMID 24520056 DOI: 10.1128/Mbio.00765-13 |
0.308 |
|
2014 |
Munagala S, Sirasani G, Kokkonda P, Phadke M, Krynetskaia N, Lu P, Sharom FJ, Chaudhury S, Abdulhameed MD, Tawa G, Wallqvist A, Martinez R, Childers W, Abou-Gharbia M, Krynetskiy E, et al. Synthesis and evaluation of Strychnos alkaloids as MDR reversal agents for cancer cell eradication. Bioorganic & Medicinal Chemistry. 22: 1148-55. PMID 24405813 DOI: 10.1016/J.Bmc.2013.12.022 |
0.326 |
|
2014 |
Perez-Leal O, Abou-Gharbia M, Gordon J, Childers WE, Merali S. A novel assay platform for the detection of translation modulators of spermidine/spermine acetyltransferase. Current Pharmaceutical Design. 20: 245-52. PMID 23701549 DOI: 10.2174/13816128113199990035 |
0.313 |
|
2012 |
Annadurai S, Martinez R, Canney DJ, Eidem T, Dunman PM, Abou-Gharbia M. Design and synthesis of 2-aminothiazole based antimicrobials targeting MRSA. Bioorganic & Medicinal Chemistry Letters. 22: 7719-25. PMID 23116888 DOI: 10.1016/J.Bmcl.2012.09.095 |
0.324 |
|
2011 |
Ghidu VP, Ilies MA, Cullen T, Pollet R, Abou-Gharbia M. A new and efficient synthetic route for the anxiolytic agent CL285032. Bioorganic & Medicinal Chemistry Letters. 21: 259-61. PMID 21095124 DOI: 10.1016/J.Bmcl.2010.11.017 |
0.302 |
|
2004 |
Elokdah H, Abou-Gharbia M, Hennan JK, McFarlane G, Mugford CP, Krishnamurthy G, Crandall DL. Tiplaxtinin, a novel, orally efficacious inhibitor of plasminogen activator inhibitor-1: Design, synthesis, and preclinical characterization Journal of Medicinal Chemistry. 47: 3491-3494. PMID 15214776 DOI: 10.1021/Jm049766Q |
0.307 |
|
2004 |
Elokdah H, Sulkowski TS, Abou-Gharbia M, Butera JA, Chai SY, McFarlane GR, McKean ML, Babiak JL, Adelman SJ, Quinet EM. Design, synthesis, and biological evaluation of thio-containing compounds with serum HDL-cholesterol-elevating properties. Journal of Medicinal Chemistry. 47: 681-95. PMID 14736248 DOI: 10.1021/Jm030219Z |
0.305 |
|
1998 |
Mewshaw RE, Marquis KL, Shi X, McGaughey G, Stack G, Webb MB, Abou-Gharbia M, Wasik T, Scerni R, Spangler T, Brennan JA, Mazandarani H, Coupet J, Andree TH. New generation dopaminergic agents 4. Exploiting the 2-methyl chroman scaffold. Synthesis and evaluation of two novel series of 2-(aminomethyl)- 3,4,7,9-tetrahydro-2H-pyrano[2,3-e]indole and indol-8-one derivatives Tetrahedron. 54: 7081-7108. DOI: 10.1016/S0040-4020(98)00349-4 |
0.328 |
|
1995 |
Abou-Gharbia M, Moyer JA, Nielsen ST, Webb M, Patel U. New antihistamines: substituted piperazine and piperidine derivatives as novel H1-antagonists. Journal of Medicinal Chemistry. 38: 4026-32. PMID 7562938 DOI: 10.1021/Jm00020A018 |
0.306 |
|
1989 |
Abou-Gharbia M, Moyer JA, Patel U, Webb M, Schiehser G, Andree T, Haskins JT. Synthesis and structure-activity relationship of substituted tetrahydro- and hexahydro-1,2-benzisothiazol-3-one 1,1-dioxides and thiadiazinones: potential anxiolytic agents. Journal of Medicinal Chemistry. 32: 1024-33. PMID 2565399 DOI: 10.1021/Jm00125A016 |
0.328 |
|
1988 |
Abou-Gharbia M, Patel UR, Webb MB, Moyer JA, Andree TH, Muth EA. Polycyclic aryl- and heteroarylpiperazinyl imides as 5-HT1A receptor ligands and potential anxiolytic agents: synthesis and structure-activity relationship studies. Journal of Medicinal Chemistry. 31: 1382-92. PMID 2898533 DOI: 10.1021/Jm00402A023 |
0.317 |
|
1987 |
Abou-Gharbia M, Patel UR, Webb MB, Moyer JA, Andree TH, Muth EA. Antipsychotic activity of substituted gamma-carbolines. Journal of Medicinal Chemistry. 30: 1818-23. PMID 2888898 DOI: 10.1021/Jm00393A023 |
0.306 |
|
1987 |
Abou-Gharbia M, Patel UR, Moyer JA, Muth EA. Psychotropic agents: synthesis and antipsychotic activity of substituted beta-carbolines. Journal of Medicinal Chemistry. 30: 1100-5. PMID 2884314 DOI: 10.1021/Jm00389A022 |
0.302 |
|
1986 |
Abou-Gharbia M. Synthesis of Novel Hexahydroquinolines and Hexahydroacridines Heterocycles. 24: 1347-1353. DOI: 10.1002/Chin.198641240 |
0.366 |
|
1985 |
Abou-Gharbia M, Hoffman BR. A New Synthesis Of 2-Bromo-1-(9-Phenanthryl)Ethane Organic Preparations and Procedures International. 16: 195-198. DOI: 10.1080/00304948509355500 |
0.346 |
|
1984 |
Abou-Gharbia MA, Joullié MM. Structural elucidation of isomeric Oxazolidinones and Isoxazolidinones by13C N. M. R. Journal FüR Praktische Chemie. 326: 1008-1010. DOI: 10.1002/prac.19843260622 |
0.371 |
|
1983 |
Ketcha DM, Abou-Gharbia M, Smith FX, Swern D. Reaction of N-acylsulfilimines with diphenyl ketene. A new synthesis of 2-oxazolin-4-ones Tetrahedron Letters. 24: 2811-2814. DOI: 10.1016/S0040-4039(00)88030-2 |
0.351 |
|
1981 |
Abou-Gharbia MA, Terwilliger DT, Joullie MM, Srivastava RM. Mass spectra of nitrones. Electron impact mass spectra of fluorenone nitrones Journal of Chemical & Engineering Data. 26: 216-218. DOI: 10.1021/je00024a038 |
0.35 |
|
1981 |
ABOU-GHARBIA MA, TERWILLIGER DT, JOULLIE MM, SRIVASTAVA RM. ChemInform Abstract: MASS SPECTRA OF NITRONES. ELECTRON IMPACT MASS SPECTRA OF FLUORENONE NITRONES Chemischer Informationsdienst. 12. DOI: 10.1002/chin.198129068 |
0.359 |
|
1980 |
Abou-Gharbia M, Joullie M. Additions and Corrections - Cyclo-additions of Ketenes with N-Fluorenylidenealklamine and -arylamine Oxides. Synthesis of Spirooxazolidinones and Spiroisoxazolidinones The Journal of Organic Chemistry. 45: 5432-5432. DOI: 10.1021/Jo01314A605 |
0.496 |
|
1980 |
Abou-Gharbia MA, Joullié MM. The mass spectra of fluorenone nitrones Organic Mass Spectrometry. 15: 489-490. DOI: 10.1002/oms.1210150915 |
0.346 |
|
1980 |
ABOU-GHARBIA MA, JOULLIE MM. ChemInform Abstract: REACTION OF TERT-BUTYLCYANOKETENE WITH 2′-CYCLOHEXYLSPIRO(FLUORENE-9,3′-OXAZIRIDINE) Chemischer Informationsdienst. 11. DOI: 10.1002/chin.198025210 |
0.427 |
|
1979 |
Abou-Gharbia MA, Joullié MM. AN IMPROVED SYNTHESIS OF FLUORENONE METHYLNITRONE Organic Preparations and Procedures International. 11: 95-96. DOI: 10.1080/00304947909354848 |
0.449 |
|
1979 |
Abou-Gharbia MA, Joullie MM. Cycloaddition of ketenes with N-fluorenylidenealkylamine and -arylamine oxides. Synthesis of spirooxazolidinones and spiroisoxazolidinones The Journal of Organic Chemistry. 44: 2961-2966. DOI: 10.1021/jo01331a002 |
0.437 |
|
1979 |
ABOU-GHARBIA MA, JOULLIE MM. ChemInform Abstract: SYNTHESIS OF SPIROFLUORENES VIA KETENE ADDUCTS Chemischer Informationsdienst. 10. DOI: 10.1002/chin.197948114 |
0.481 |
|
1979 |
ABOU-GHARBIA MA, JOULLIE MM. ChemInform Abstract: REACTIONS OF NITRONES WITH KETENES Chemischer Informationsdienst. 10. DOI: 10.1002/chin.197944370 |
0.393 |
|
1979 |
ABOU-GHARBIA MA, JOULLIE MM. ChemInform Abstract: AN IMPROVED SYNTHESIS OF FLUORENONE METHYLNITRONE Chemischer Informationsdienst. 10. DOI: 10.1002/chin.197942198 |
0.462 |
|
1978 |
Abou-Gharbia MA, Su TT, Joullié MM. Synthesis of spirofluorenes of biological interest. Journal of Pharmaceutical Sciences. 67: 953-6. PMID 660513 DOI: 10.1002/jps.2600670721 |
0.5 |
|
1978 |
ABOU-GHARBIA MA, SU TT, JOULLIE MM. ChemInform Abstract: SYNTHESIS OF SPIROFLUORENES OF BIOLOGICAL INTEREST Chemischer Informationsdienst. 9. DOI: 10.1002/chin.197847160 |
0.475 |
|
1978 |
ABOU-GHARBIA MA, JOULLIE MM, MIURA I. ChemInform Abstract: THE REGIOSELECTIVITY OF THE CYCLOADDITIONS OF KETENES WITH N-ALKYL- AND N-ARYLNITRONES Chemischer Informationsdienst. 9. DOI: 10.1002/chin.197837222 |
0.414 |
|
1978 |
ABOU-GHARBIA M, JOULLIE MM. ChemInform Abstract: SYNTHESIS AND HYDROLYSIS OF FLUORENE-9-SPIRO-2′-(N-ARYL-3′,3′-DICHLOROAZIRIDINES) Chemischer Informationsdienst. 9. DOI: 10.1002/Chin.197816166 |
0.53 |
|
1977 |
Abou-Gharbia M, Joullié MM. Synthesis and hydrolysis of fluorene-9-spiro-2'-(N-aryl-3' ,3'-dichloroaziridines) Journal of Pharmaceutical Sciences. 66: 1653-5. PMID 915756 DOI: 10.1002/Jps.2600661146 |
0.523 |
|
1977 |
ABOU-GHARBIA M, JOULLIÉ MM. A New Synthesis of Nitrones Synthesis. 1977: 318-320. DOI: 10.1055/S-1977-24378 |
0.513 |
|
1977 |
ABOU-GHARBIA M, JOULLIE MM. ChemInform Abstract: A NEW SYNTHESIS OF NITRONES Chemischer Informationsdienst. 8: no-no. DOI: 10.1002/chin.197735173 |
0.469 |
|
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