| Year |
Citation |
Score |
| 2023 |
Zhou J, Nie RC, He ZP, Cai XX, Chen JW, Lin WP, Yin YX, Xiang ZC, Zhu TC, Xie JJ, Zhang YC, Wang X, Lin P, Xie D, D'Andrea AD, et al. STAG2 Regulates Homologous Recombination Repair and Sensitivity to ATM Inhibition. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2302494. PMID 37985839 DOI: 10.1002/advs.202302494 |
0.358 |
|
| 2023 |
Swift ML, Zhou R, Syed A, Moreau LA, Tomasik B, Tainer JA, Konstantinopoulos PA, D'Andrea AD, He YJ, Chowdhury D. Dynamics of the DYNLL1-MRE11 complex regulate DNA end resection and recruitment of Shieldin to DSBs. Nature Structural & Molecular Biology. PMID 37696958 DOI: 10.1038/s41594-023-01074-9 |
0.406 |
|
| 2022 |
Iyer DR, Harada N, Clairmont C, Jiang L, Martignetti D, Nguyen H, He YJ, Chowdhury D, D'Andrea AD. CCAR2 functions downstream of the Shieldin complex to promote double-strand break end-joining. Proceedings of the National Academy of Sciences of the United States of America. 119: e2214935119. PMID 36442094 DOI: 10.1073/pnas.2214935119 |
0.382 |
|
| 2022 |
Li F, Sarangi P, Iyer DR, Feng H, Moreau L, Nguyen H, Clairmont C, D'Andrea AD. CHAMP1 binds to REV7/FANCV and promotes homologous recombination repair. Cell Reports. 40: 111297. PMID 36044844 DOI: 10.1016/j.celrep.2022.111297 |
0.358 |
|
| 2022 |
Patterson-Fortin J, Bose A, Tsai WC, Grochala CJ, Nguyen H, Zhou J, Parmar K, Lazaro JB, Liu JF, McQueen K, Shapiro GI, Kozono D, D'Andrea AD. Targeting DNA repair with combined inhibition of NHEJ and MMEJ induces synthetic lethality in TP53-mutant cancers. Cancer Research. PMID 35972384 DOI: 10.1158/0008-5472.CAN-22-1124 |
0.399 |
|
| 2021 |
Adeyemi RO, Willis NA, Elia AEH, Clairmont C, Li S, Wu X, D'Andrea AD, Scully R, Elledge SJ. The Protexin complex counters resection on stalled forks to promote homologous recombination and crosslink repair. Molecular Cell. PMID 34597596 DOI: 10.1016/j.molcel.2021.09.008 |
0.402 |
|
| 2021 |
Cleary JM, Wolpin BM, Dougan SK, Raghavan S, Singh H, Huffman B, Sethi NS, Nowak JA, Shapiro GI, Aguirre AJ, D'Andrea AD. Opportunities for Utilization of DNA Repair Inhibitors in Homologous Recombination Repair-Deficient and Proficient Pancreatic Adenocarcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 34285063 DOI: 10.1158/1078-0432.CCR-21-1367 |
0.376 |
|
| 2021 |
Shah RB, Kernan JL, van Hoogstraten A, Ando K, Li Y, Belcher AL, Mininger I, Bussenault AM, Raman R, Ramanagoudr-Bhojappa R, Huang TT, D'Andrea AD, Chandrasekharappa SC, Aggarwal AK, Thompson R, et al. FANCI functions as a repair/apoptosis switch in response to DNA crosslinks. Developmental Cell. PMID 34256011 DOI: 10.1016/j.devcel.2021.06.010 |
0.321 |
|
| 2021 |
Clairmont CS, D'Andrea AD. REV7 directs DNA repair pathway choice. Trends in Cell Biology. PMID 34147298 DOI: 10.1016/j.tcb.2021.05.009 |
0.384 |
|
| 2020 |
Tothova Z, Valton AL, Gorelov R, Vallurupalli M, Krill-Burger JM, Holmes A, Landers CC, Haydu JE, Malolepsza E, Hartigan CR, Donahue M, Popova KD, Koochaki SHJ, Venev SV, Rivera JF, et al. Cohesin mutations alter DNA damage repair and chromatin structure and create therapeutic vulnerabilities in MDS/AML. Jci Insight. PMID 33351783 DOI: 10.1172/jci.insight.142149 |
0.378 |
|
| 2020 |
Sarangi P, Clairmont CS, Galli LD, Moreau LA, D'Andrea AD. p31 promotes homologous recombination by inactivating REV7 through the TRIP13 ATPase. Proceedings of the National Academy of Sciences of the United States of America. PMID 33051298 DOI: 10.1073/pnas.2008830117 |
0.375 |
|
| 2020 |
Patterson-Fortin J, D'Andrea AD. Exploiting the Microhomology-Mediated End-Joining Pathway in Cancer Therapy. Cancer Research. PMID 32651257 DOI: 10.1158/0008-5472.Can-20-1672 |
0.447 |
|
| 2020 |
Konstantinopoulos PA, Cheng SC, Wahner Hendrickson AE, Penson RT, Schumer ST, Doyle LA, Lee EK, Kohn EC, Duska LR, Crispens MA, Olawaiye AB, Winer IS, Barroilhet LM, Fu S, McHale MT, et al. Berzosertib plus gemcitabine versus gemcitabine alone in platinum-resistant high-grade serous ovarian cancer: a multicentre, open-label, randomised, phase 2 trial. The Lancet. Oncology. PMID 32553118 DOI: 10.1016/S1470-2045(20)30180-7 |
0.328 |
|
| 2020 |
Carbone M, Arron ST, Beutler B, Bononi A, Cavenee W, Cleaver JE, Croce CM, D'Andrea A, Foulkes WD, Gaudino G, Groden JL, Henske EP, Hickson ID, Hwang PM, Kolodner RD, et al. Tumour predisposition and cancer syndromes as models to study gene-environment interactions. Nature Reviews. Cancer. PMID 32472073 DOI: 10.1038/S41568-020-0265-Y |
0.344 |
|
| 2020 |
Cleary JM, Aguirre AJ, Shapiro GI, D'Andrea AD. Biomarker-Guided Development of DNA Repair Inhibitors. Molecular Cell. PMID 32459988 DOI: 10.1016/j.molcel.2020.04.035 |
0.391 |
|
| 2020 |
Sarangi P, Clairmont CS, D'Andrea AD. Disassembly of the Shieldin Complex by TRIP13. Cell Cycle (Georgetown, Tex.). 1-11. PMID 32420796 DOI: 10.1080/15384101.2020.1758435 |
0.371 |
|
| 2020 |
Cai MY, Dunn CE, Chen W, Kochupurakkal BS, Nguyen H, Moreau LA, Shapiro GI, Parmar K, Kozono D, D'Andrea AD. Cooperation of the ATM and Fanconi Anemia/BRCA Pathways in Double-Strand Break End Resection. Cell Reports. 30: 2402-2415.e5. PMID 32075772 DOI: 10.1016/J.Celrep.2020.01.052 |
0.351 |
|
| 2020 |
Li N, Wang J, Wallace SS, Chen J, Zhou J, D'Andrea AD. Cooperation of the NEIL3 and Fanconi anemia/BRCA pathways in interstrand crosslink repair. Nucleic Acids Research. PMID 31980815 DOI: 10.1093/nar/gkaa038 |
0.354 |
|
| 2020 |
Clairmont CS, Sarangi P, Ponnienselvan K, Galli LD, Csete I, Moreau L, Adelmant G, Chowdhury D, Marto JA, D'Andrea AD. TRIP13 regulates DNA repair pathway choice through REV7 conformational change. Nature Cell Biology. 22: 87-96. PMID 31915374 DOI: 10.1038/S41556-019-0442-Y |
0.408 |
|
| 2020 |
Choudhury AD, Xie W, Parikh M, Lee D, Kessler ER, Einstein DJ, Kochupurakkal B, Mouw KW, Van Allen EM, Doyle LA, D'Andrea AD, Taplin M, Shapiro G. A phase II study of M6620 in combination with carboplatin compared with docetaxel in combination with carboplatin in metastatic castration-resistant prostate cancer. Journal of Clinical Oncology. 38: TPS5597-TPS5597. DOI: 10.1200/Jco.2020.38.15_Suppl.Tps5597 |
0.357 |
|
| 2020 |
Hill SJ, Lizotte P, Kesten N, Horowitz NS, Muto MG, Worley MJ, Feltmate CM, Berkowitz RS, Long H, Matulonis UA, Crum CP, Brown M, D'Andrea AD. Abstract PR06: Dissecting mechanisms of replication fork stabilization in patient-derived high-grade serous organoid cultures and their impact on therapeutic sensitivity and the immune-tumor interaction Clinical Cancer Research. 26. DOI: 10.1158/1557-3265.Ovca19-Pr06 |
0.387 |
|
| 2019 |
Pouliot GP, Degar J, Hinze L, Kochupurakkal B, Vo CD, Burns MA, Moreau L, Ganesa C, Roderick J, Peirs S, Menten B, Loh ML, Hunger SP, Silverman LB, Harris MH, et al. Fanconi-BRCA pathway mutations in childhood T-cell acute lymphoblastic leukemia. Plos One. 14: e0221288. PMID 31721781 DOI: 10.1371/Journal.Pone.0221288 |
0.343 |
|
| 2019 |
Parmar K, Kochupurakkal BS, Lazaro JB, Wang ZC, Palakurthi S, Kirschmeier PT, Yang C, Sambel LA, Färkkilä A, Reznichenko E, Reavis HD, Dunn CE, Zou L, Do KT, Konstantinopoulos PA, et al. The CHK1 Inhibitor Prexasertib Exhibits Monotherapy Activity in High-Grade Serous Ovarian Cancer Models and Sensitizes to PARP inhibition. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31409614 DOI: 10.1158/1078-0432.Ccr-19-0448 |
0.334 |
|
| 2019 |
Chan EM, Shibue T, McFarland JM, Gaeta B, Ghandi M, Dumont N, Gonzalez A, McPartlan JS, Li T, Zhang Y, Bin Liu J, Lazaro JB, Gu P, Piett CG, Apffel A, et al. WRN helicase is a synthetic lethal target in microsatellite unstable cancers. Nature. PMID 30971823 DOI: 10.1038/S41586-019-1102-X |
0.469 |
|
| 2019 |
Niraj J, Färkkilä A, D'Andrea AD. The Fanconi Anemia Pathway in Cancer. Annual Review of Cancer Biology. 3: 457-478. PMID 30882047 DOI: 10.1146/annurev-cancerbio-030617-050422 |
0.381 |
|
| 2019 |
Mengwasser KE, Adeyemi RO, Leng Y, Choi MY, Clairmont C, D'Andrea AD, Elledge SJ. Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets. Molecular Cell. PMID 30686591 DOI: 10.1016/J.Molcel.2018.12.008 |
0.323 |
|
| 2019 |
Waks AG, Cohen O, Kochupurakkal B, Kim D, Wander SA, Buendia-Buendia J, Helvie K, Matulonis UA, Krop IE, Tolaney SM, Winer EP, D'Andrea AD, Shapiro G, Lin NU, Wagle N. Reversion and non-reversion mechanisms of resistance (MoR) to PARP inhibitor (PARPi) or platinum chemotherapy (chemotx) in patients (pts) with BRCA1/2-mutant metastatic breast cancer (MBC). Journal of Clinical Oncology. 37: 1085-1085. DOI: 10.1200/Jco.2019.37.15_Suppl.1085 |
0.387 |
|
| 2019 |
Hill SJ, Decker B, Roberts EA, Yang C, Horowitz NS, Muto MG, Worley MJ, Feltmate CM, Nucci MR, Swisher EM, Morizane R, Kochupurakkal B, Do KT, Konstantinopoulos P, Liu JF, et al. Abstract AP10: REAL-TIME ASSESSMENT OF HGSC DNA DAMAGE REPAIR DEFECTS AND DEFECT-INDUCED RESPONSE TO THERAPY IN OVARIAN CANCER ORGANOIDS Clinical Cancer Research. 25. DOI: 10.1158/1557-3265.Ovcasymp18-Ap10 |
0.43 |
|
| 2019 |
Hill SJ, Lizotte P, Horowitz NS, Muto MG, Worley MJ, Feltmate CM, Kochupurakkal B, Do KT, Konstantinopoulos P, Nucci MR, Liu JF, Matulonis UA, Shapiro GI, Berkowitz RS, Crum CP, et al. Abstract 368A: Functional assessment of DNA damage repair defects and the anti-tumor immune response in high grade serous ovarian cancers using patient-derived organoids Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-368A |
0.425 |
|
| 2019 |
Do KT, Hill SJ, Kochupurakkal B, Supko JG, Gannon C, Anderson A, Muzikansky A, Wolanski A, Hedglin J, Parmar K, Lazaro J, Liu J, Campos S, Matulonis UA, D'Andrea AD, et al. Abstract CT232: Phase I combination study of the CHK1 inhibitor prexasertib (LY2606368) and olaparib in patients with high-grade serous ovarian cancer and other advanced solid tumors Cancer Research. 79. DOI: 10.1158/1538-7445.Am2019-Ct232 |
0.355 |
|
| 2018 |
Lim KS, Li H, Roberts EA, Gaudiano EF, Clairmont C, Sambel LA, Ponnienselvan K, Liu JC, Yang C, Kozono D, Parmar K, Yusufzai T, Zheng N, D'Andrea AD. USP1 Is Required for Replication Fork Protection in BRCA1-Deficient Tumors. Molecular Cell. 72: 925-941.e4. PMID 30576655 DOI: 10.1016/J.Molcel.2018.10.045 |
0.359 |
|
| 2018 |
He YJ, Meghani K, Caron MC, Yang C, Ronato DA, Bian J, Sharma A, Moore J, Niraj J, Detappe A, Doench JG, Legube G, Root DE, D'Andrea AD, Drané P, et al. DYNLL1 binds to MRE11 to limit DNA end resection in BRCA1-deficient cells. Nature. 563: 522-526. PMID 30464262 DOI: 10.1038/S41586-018-0670-5 |
0.377 |
|
| 2018 |
Przetocka S, Porro A, Bolck HA, Walker C, Lezaja A, Trenner A, von Aesch C, Himmels SF, D'Andrea AD, Ceccaldi R, Altmeyer M, Sartori AA. CtIP-Mediated Fork Protection Synergizes with BRCA1 to Suppress Genomic Instability upon DNA Replication Stress. Molecular Cell. PMID 30344097 DOI: 10.1016/j.molcel.2018.09.014 |
0.38 |
|
| 2018 |
Hill SJ, Decker B, Roberts EA, Horowitz NS, Muto MG, Worley MJ, Feltmate CM, Nucci MR, Swisher EM, Nguyen H, Yang C, Morizane R, Kochupurakkal BS, Do KT, Konstantinopoulos PA, et al. Prediction of DNA Repair Inhibitor Response in Short Term Patient-Derived Ovarian Cancer Organoids. Cancer Discovery. PMID 30213835 DOI: 10.1158/2159-8290.Cd-18-0474 |
0.449 |
|
| 2018 |
Li N, Ding L, Li B, Wang J, D'Andrea AD, Chen J. Functional Analysis of Fanconi Anemia Mutations in China. Experimental Hematology. PMID 30031030 DOI: 10.1016/J.Exphem.2018.07.003 |
0.356 |
|
| 2018 |
Li Q, Damish A, Frazier ZJ, Liu D, Reznichenko E, Kamburov A, Bell A, Zhao H, Jordan EJ, Gao SP, Ma J, Abbosh PH, Bellmunt J, Plimack ER, Lazaro JB, et al. ERCC2 Helicase Domain Mutations Confer Nucleotide Excision Repair Deficiency and Drive Cisplatin Sensitivity in Muscle-Invasive Bladder Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 29980530 DOI: 10.1158/1078-0432.Ccr-18-1001 |
0.369 |
|
| 2018 |
Andrews AM, McCartney HJ, Errington TM, D'Andrea AD, Macara IG. A senataxin-associated exonuclease SAN1 is required for resistance to DNA interstrand cross-links. Nature Communications. 9: 2592. PMID 29968717 DOI: 10.1038/S41467-018-05008-8 |
0.509 |
|
| 2018 |
Mouw KW, D'Andrea AD. DNA Repair Deficiency and Immunotherapy Response. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2018782425. PMID 29683789 DOI: 10.1200/Jco.2018.78.2425 |
0.322 |
|
| 2018 |
Tothova Z, Krill-Burger JM, Day DS, Haydu JE, Abraham BJ, Landers CC, Malolepsza E, Hartigan CR, Holmes A, Donahue M, Popova KD, Koochaki S, Rivera J, Seiler M, Hnisz D, et al. STAG2 Mutations Alter Cohesin Ring Function and Provide Therapeutic Vulnerabilities in Acute Myeloid Leukemia Blood. 132: 940-940. DOI: 10.1182/Blood-2018-99-117480 |
0.499 |
|
| 2018 |
D'Andrea AD. Abstract IA20: Targeting DNA repair in cancer therapy Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Tcm17-Ia20 |
0.483 |
|
| 2018 |
Deraska P, Reavis H, Labe S, D'Andrea A, Kozono D. Abstract 4287: Whole-genome CRISPR/Cas9 screen of the CHK1 inhibitor prexasertib implicates FAM122A loss as a potential resistance mechanism Cancer Research. 78: 4287-4287. DOI: 10.1158/1538-7445.Am2018-4287 |
0.379 |
|
| 2018 |
Lim KS, Li H, Roberts EA, Gaudiano EF, Clairmont C, Ponnienselvan K, Liu JC, Parmar K, Zheng N, D'Andrea A. Abstract 333: USP1 is required for replication fork stability in BRCA1-deficient tumors Cancer Research. 78: 333-333. DOI: 10.1158/1538-7445.Am2018-333 |
0.476 |
|
| 2018 |
Cai M, Reavis HD, Chen J, Ganesa C, Kochupurakkal B, Shapiro GI, D'Andrea AD. Abstract 1620: ATR inhibition for the treatment of ATM-deficient gastric cancer Cancer Research. 78: 1620-1620. DOI: 10.1158/1538-7445.Am2018-1620 |
0.344 |
|
| 2018 |
Farkkila A, Chopra SS, Lin J, Maliga Z, Koruchupakkal B, Strickland KC, Howitt BE, Santagata S, Matulonis UA, Elias K, Swisher EM, Konstantinopoulos PA, Sorger P, D'Andrea AD. Abstract 139: DNA damage and immunoprofiling with highly multiplexed tissue immunofluorescence (t-CycIF) in high-grade serous ovarian cancer Cancer Research. 78: 139-139. DOI: 10.1158/1538-7445.Am2018-139 |
0.447 |
|
| 2018 |
D'Andrea AD. Abstract CN05-02: Novel mechanisms of PARP inhibitor resistance Molecular Cancer Therapeutics. 17. DOI: 10.1158/1535-7163.Targ-17-Cn05-02 |
0.382 |
|
| 2017 |
Rodríguez A, D'Andrea A. Fanconi anemia pathway. Current Biology : Cb. 27: R986-R988. PMID 28950089 DOI: 10.1016/j.cub.2017.07.043 |
0.329 |
|
| 2017 |
Polak P, Kim J, Braunstein LZ, Karlic R, Haradhavala NJ, Tiao G, Rosebrock D, Livitz D, Kübler K, Mouw KW, Kamburov A, Maruvka YE, Leshchiner I, Lander ES, Golub TR, et al. A mutational signature reveals alterations underlying deficient homologous recombination repair in breast cancer. Nature Genetics. PMID 28825726 DOI: 10.1038/Ng.3934 |
0.302 |
|
| 2017 |
Mouw KW, Goldberg MS, Konstantinopoulos PA, D'Andrea AD. DNA Damage and Repair Biomarkers of Immunotherapy Response. Cancer Discovery. PMID 28630051 DOI: 10.1158/2159-8290.Cd-17-0226 |
0.421 |
|
| 2017 |
Pouliot GP, Burns MA, Degar J, Vo C, Moreau L, Roderick JE, Kochupurakkal B, Peirs S, Menten B, Loh ML, Hunger SP, Silverman LB, Sallan SE, Harris MH, Stevenson KE, et al. The Fanconi Pathway in Pediatric T-Cell Acute Lymphoblastic Leukemia Blood. 130: 2722-2722. DOI: 10.1182/Blood.V130.Suppl_1.2722.2722 |
0.334 |
|
| 2017 |
D'Andrea AD. Abstract IA12: Targeting DNA repair in cancer therapy Clinical Cancer Research. 23. DOI: 10.1158/1557-3265.Pmccavuln16-Ia12 |
0.482 |
|
| 2017 |
Mouw K, Lazaro J, Damish A, Reznichenko E, Frazier Z, Liu D, Kim J, Polak P, Garraway L, Getz G, Rosenberg J, Allen EV, D'Andrea A. Abstract PR18: Somatic ERCC2 mutations, nucleotide excision repair (NER) function, and cisplatin response in muscle-invasive bladder cancer (MIBC) Molecular Cancer Research. 15. DOI: 10.1158/1557-3125.Dnarepair16-Pr18 |
0.385 |
|
| 2017 |
D'Andrea AD. Abstract IA25: Novel mechanisms of PARP-inhibitor resistance in tumors with defects in the Fanconi Anemia/BRCA pathway Molecular Cancer Research. 15. DOI: 10.1158/1557-3125.Dnarepair16-Ia25 |
0.462 |
|
| 2017 |
D'Andrea AD. Abstract IA12: Targeting DNA repair in cancer therapy Cancer Research. 77. DOI: 10.1158/1538-7445.Newfront17-Ia12 |
0.482 |
|
| 2017 |
D'Andrea AD. Abstract SY29-02: Novel mechanisms of PARP inhibitor resistance Cancer Research. 77. DOI: 10.1158/1538-7445.Am2017-Sy29-02 |
0.383 |
|
| 2017 |
Shapiro GI, Do KT, Tolaney SM, Hilton JF, Cleary JM, Wolanski A, Beardslee B, Hassinger F, Bhushan K, Cai D, Downey E, Pruitt-Thompson S, Barry SM, Kochupurakkal B, Geradts J, et al. Abstract CT047: Phase 1 dose-escalation study of the CDK inhibitor dinaciclib in combination with the PARP inhibitor veliparib in patients with advanced solid tumors Cancer Research. 77. DOI: 10.1158/1538-7445.Am2017-Ct047 |
0.301 |
|
| 2017 |
Deraska PV, Reavis HD, Labe S, D'Andrea AD, Kozono D. Abstract 4189: Homologous recombination pathway-based biomarkers for treatment of non-small cell lung cancer with PARP inhibitors Cancer Research. 77: 4189-4189. DOI: 10.1158/1538-7445.Am2017-4189 |
0.386 |
|
| 2017 |
Kochupurakkal BS, Parmar K, Lazaro J, Unitt C, Zeng Q, Reavis H, Ganesa C, Zhou S, Liu J, Palakurthi S, Strickland K, Howitt B, Konstantinopoulos P, Kirschmeier P, Geradts J, et al. Abstract 2796: Development of a RAD51-based assay for determining homologous recombination proficiency and PARP inhibitor sensitivity Cancer Research. 77: 2796-2796. DOI: 10.1158/1538-7445.Am2017-2796 |
0.37 |
|
| 2016 |
Jo U, Cai W, Wang J, Kwon Y, D'Andrea AD, Kim H. PCNA-Dependent Cleavage and Degradation of SDE2 Regulates Response to Replication Stress. Plos Genetics. 12: e1006465. PMID 27906959 DOI: 10.1371/Journal.Pgen.1006465 |
0.377 |
|
| 2016 |
Johnson SF, Cruz C, Greifenberg AK, Dust S, Stover DG, Chi D, Primack B, Cao S, Bernhardy AJ, Coulson R, Lazaro JB, Kochupurakkal B, Sun H, Unitt C, Moreau LA, et al. CDK12 Inhibition Reverses De Novo and Acquired PARP Inhibitor Resistance in BRCA Wild-Type and Mutated Models of Triple-Negative Breast Cancer. Cell Reports. 17: 2367-2381. PMID 27880910 DOI: 10.1016/J.Celrep.2016.10.077 |
0.339 |
|
| 2016 |
Davis MI, Pragani R, Fox JT, Shen M, Parmar K, Gaudiano EF, Liu L, Tanega C, McGee L, Hall MD, McKnight C, Shinn P, Nelson H, Chattopadhyay D, D'Andrea AD, et al. Small Molecule Inhibition of the Ubiquitin-specific Protease USP2 Accelerates Cyclin D1 Degradation and Leads to Cell Cycle Arrest in Colorectal Cancer and Mantle Cell Lymphoma Models. The Journal of Biological Chemistry. PMID 27681596 DOI: 10.1074/Jbc.M116.738567 |
0.441 |
|
| 2016 |
Bluteau D, Masliah-Planchon J, Clairmont C, Rousseau A, Ceccaldi R, Dubois d'Enghien C, Bluteau O, Cuccuini W, Gachet S, Peffault de Latour R, Leblanc T, Socié G, Baruchel A, Stoppa-Lyonnet D, D'Andrea AD, et al. Biallelic inactivation of REV7 is associated with Fanconi anemia. The Journal of Clinical Investigation. PMID 27500492 DOI: 10.1172/JCI88010 |
0.402 |
|
| 2016 |
Kais Z, Rondinelli B, Holmes A, O'Leary C, Kozono D, D'Andrea AD, Ceccaldi R. FANCD2 Maintains Fork Stability in BRCA1/2-Deficient Tumors and Promotes Alternative End-Joining DNA Repair. Cell Reports. PMID 27264184 DOI: 10.1016/J.Celrep.2016.05.031 |
0.377 |
|
| 2016 |
Wang Y, Bernhardy AJ, Cruz C, Krais JJ, Nacson J, Nicolas E, Peri S, van der Gulden H, van der Heijden I, O'Brien SW, Zhang Y, Harrell MI, Johnson SF, Candido Dos Reis FJ, Pharoah PD, et al. The BRCA1-Δ11q Alternative Splice Isoform Bypasses Germline Mutations and Promotes Therapeutic Resistance to PARP Inhibition and Cisplatin. Cancer Research. 76: 2778-2790. PMID 27197267 DOI: 10.1158/0008-5472.Can-16-0186 |
0.321 |
|
| 2016 |
Ceccaldi R, Sarangi P, D'Andrea AD. The Fanconi anaemia pathway: new players and new functions. Nature Reviews. Molecular Cell Biology. PMID 27145721 DOI: 10.1038/Nrm.2016.48 |
0.434 |
|
| 2016 |
Kim J, Mouw KW, Polak P, Braunstein LZ, Kamburov A, Tiao G, Kwiatkowski DJ, Rosenberg JE, Van Allen EM, D'Andrea AD, Getz G. Somatic ERCC2 mutations are associated with a distinct genomic signature in urothelial tumors. Nature Genetics. PMID 27111033 DOI: 10.1038/Ng.3557 |
0.356 |
|
| 2016 |
Ceccaldi R, Rondinelli B, D'Andrea AD. Repair Pathway Choices and Consequences at the Double-Strand Break. Trends in Cell Biology. 26: 52-64. PMID 26437586 DOI: 10.1016/j.tcb.2015.07.009 |
0.322 |
|
| 2016 |
Pike JW, Mouw KW, Braunstein LZ, Martin NE, Mamon HJ, Hornick JL, Van Allen EM, D'Andrea AD. Genomic features of primary and recurrent anal squamous cell carcinoma. Journal of Clinical Oncology. 34: 556-556. DOI: 10.1200/Jco.2016.34.4_Suppl.556 |
0.304 |
|
| 2016 |
Konstantinopoulos P, Palakurthi S, Zeng Q, Zhou S, Liu JF, Ivanova E, Paweletz C, Kommajosyula N, D'Andrea AD, Shapiro G, Matulonis UA. In vivo synergism between PARP-inhibitor olaparib and HSP90-inhibitor AT13387 in high grade serous ovarian cancer patient derived xenografts. Journal of Clinical Oncology. 34: e17045-e17045. DOI: 10.1200/Jco.2016.34.15_Suppl.E17045 |
0.376 |
|
| 2016 |
O'Connor K, Vidal-Cardenas S, Zhang H, Rodriguez A, Moreau L, Yang C, Epperly MW, Grompe M, Shimamura A, Greenberger JS, Parmar K, D'Andrea AD. Hyperactive Non-Canonical TGF-β Pathway Signaling in Fanconi Anemia Bone Marrow Stromal Cells Contributes to Growth Suppression Blood. 128: 1039-1039. DOI: 10.1182/Blood.V128.22.1039.1039 |
0.346 |
|
| 2015 |
Konstantinopoulos PA, Ceccaldi R, Shapiro GI, D'Andrea AD. Homologous Recombination Deficiency: Exploiting the Fundamental Vulnerability of Ovarian Cancer. Cancer Discovery. 5: 1137-54. PMID 26463832 DOI: 10.1158/2159-8290.Cd-15-0714 |
0.404 |
|
| 2015 |
Xie J, Kim H, Moreau LA, Puhalla S, Garber J, Al Abo M, Takeda S, D'Andrea AD. RNF4-mediated polyubiquitination regulates the Fanconi anemia/BRCA pathway. The Journal of Clinical Investigation. 125: 1523-32. PMID 25751062 DOI: 10.1172/Jci79325 |
0.42 |
|
| 2015 |
Ceccaldi R, Liu JC, Amunugama R, Hajdu I, Primack B, Petalcorin MI, O'Connor KW, Konstantinopoulos PA, Elledge SJ, Boulton SJ, Yusufzai T, D'Andrea AD. Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair. Nature. 518: 258-62. PMID 25642963 DOI: 10.1038/Nature14184 |
0.41 |
|
| 2015 |
Ceccaldi R, O'Connor KW, Mouw KW, Li AY, Matulonis UA, D'Andrea AD, Konstantinopoulos PA. A unique subset of epithelial ovarian cancers with platinum sensitivity and PARP inhibitor resistance. Cancer Research. 75: 628-34. PMID 25634215 DOI: 10.1158/0008-5472.Can-14-2593 |
0.407 |
|
| 2015 |
Zhang H, Kozono D, O'Connor K, Rousseau A, Moreau L, Gaudiano E, Greenberger JS, Bagby GC, Soulier J, Grompe M, Parmar K, D'Andrea AD. TGF-β Pathway Inhibition Rescues the Function of Hematopoietic Stem and Progenitor Cells Derived from Patients with Fanconi Anemia Blood. 126: 297-297. DOI: 10.1182/Blood.V126.23.297.297 |
0.331 |
|
| 2015 |
Ceccaldi R, O'Connor K, Mouw KW, Li AY, Matulonis UA, D'Andrea AD, Konstantinopoulos PA. Abstract POSTER-BIOL-1331: Nucleotide excision repair mutations confer sensitivity to platinum but not PARP-inhibitors in epithelial ovarian cancer Clinical Cancer Research. 21. DOI: 10.1158/1557-3265.Ovcasymp14-Poster-Biol-1331 |
0.413 |
|
| 2015 |
O'Leary C, Deraska P, Sweeney C, D'Andrea A, Kozono D. Abstract 3336: NF-κB inhibition by DMAPT radiosensitizes non-small cell lung carcinoma by impairing DNA double strand break repair Cancer Research. 75: 3336-3336. DOI: 10.1158/1538-7445.Am2015-3336 |
0.38 |
|
| 2015 |
D'Andrea AD. Abstract PL05-02: Synthetic Lethal Interaction between Homologous Recombination Repair and POLQ-mediated Alternative End-Joining Molecular Cancer Therapeutics. 14. DOI: 10.1158/1535-7163.Targ-15-Pl05-02 |
0.493 |
|
| 2014 |
Wojtaszek JL, Wang S, Kim H, Wu Q, D'Andrea AD, Zhou P. Ubiquitin recognition by FAAP20 expands the complex interface beyond the canonical UBZ domain. Nucleic Acids Research. 42: 13997-4005. PMID 25414354 DOI: 10.1093/Nar/Gku1153 |
0.447 |
|
| 2014 |
Van Allen EM, Mouw KW, Kim P, Iyer G, Wagle N, Al-Ahmadie H, Zhu C, Ostrovnaya I, Kryukov GV, O'Connor KW, Sfakianos J, Garcia-Grossman I, Kim J, Guancial EA, Bambury R, et al. Somatic ERCC2 mutations correlate with cisplatin sensitivity in muscle-invasive urothelial carcinoma. Cancer Discovery. 4: 1140-53. PMID 25096233 DOI: 10.1158/2159-8290.Cd-14-0623 |
0.316 |
|
| 2014 |
Mouw KW, D'Andrea AD. Crosstalk between the nucleotide excision repair and Fanconi anemia/BRCA pathways. Dna Repair. 19: 130-4. PMID 24768451 DOI: 10.1016/J.Dnarep.2014.03.019 |
0.371 |
|
| 2014 |
Kim H, Dejsuphong D, Adelmant G, Ceccaldi R, Yang K, Marto JA, D'Andrea AD. Transcriptional repressor ZBTB1 promotes chromatin remodeling and translesion DNA synthesis. Molecular Cell. 54: 107-18. PMID 24657165 DOI: 10.1016/J.Molcel.2014.02.017 |
0.633 |
|
| 2014 |
Polito D, Cukras S, Wang X, Spence P, Moreau L, D'Andrea AD, Kee Y. The carboxyl terminus of FANCE recruits FANCD2 to the Fanconi Anemia (FA) E3 ligase complex to promote the FA DNA repair pathway. The Journal of Biological Chemistry. 289: 7003-10. PMID 24451376 DOI: 10.1074/Jbc.M113.533976 |
0.534 |
|
| 2014 |
Rosenberg JE, Van Allen EM, Mouw KW, Kim PH, Wagle N, Al-Ahmadie H, Zhu C, Ostrovnaya I, Iyer G, Signoretti S, Reuter VE, Getz G, Kantoff PW, Bochner BH, Choueiri TK, et al. Association of somatic ERCC2 mutations with cisplatin sensitivity in muscle-invasive urothelial carcinoma. Journal of Clinical Oncology. 32: 4510-4510. DOI: 10.1200/Jco.2014.32.15_Suppl.4510 |
0.333 |
|
| 2014 |
Zhang H, Kozono D, O'Connor K, Vidal-Cardenas S, Hamilton A, Gaudiano E, Greenberger JS, Grompe M, Parmar K, D'Andrea AD. Bone Marrow Failure in Fanconi Anemia from Hyperactive TGF-β Signaling Blood. 124: 356-356. DOI: 10.1182/Blood.V124.21.356.356 |
0.358 |
|
| 2014 |
D'Andrea AD. Abstract IA10: Fanconi anemia and novel drug targets Cancer Research. 74. DOI: 10.1158/1538-7445.Pedcan-Ia10 |
0.461 |
|
| 2014 |
Grompe M, Postlethwait J, D'Andrea A, Olson S, Zhang Q, Bagby G. Abstract IA05: Fanconi's anemia: Emerging therapeutic opportunities Cancer Research. 74. DOI: 10.1158/1538-7445.Cansusc14-Ia05 |
0.377 |
|
| 2014 |
Brown AL, Gray JX, Leo P, Zeya MK, Bassal M, Engler G, Bray S, Gardiner B, Marshall M, Tiong IS, Cummings N, Wei A, To B, Lewis I, D'Andrea A, et al. Abstract 23: Somatic mutation of cancer susceptibility genes in acute myeloid leukemia Cancer Research. 74: 23-23. DOI: 10.1158/1538-7445.Cansusc14-23 |
0.31 |
|
| 2014 |
Johnson S, Johnson N, Chi D, Primack B, Cruz C, Stover D, Greifenberg A, Cao S, O'Connor K, Baselga J, Balmaña J, Serra V, Geyer M, D'Andrea A, Lim E, et al. 238 Reversal of primary and acquired PARP-inhibitor resistance in BRCA-mutated triple-negative breast cancers by inhibition of transcriptional cyclin-dependent kinases (CDKs) European Journal of Cancer. 50: 80. DOI: 10.1016/S0959-8049(14)70364-8 |
0.3 |
|
| 2013 |
Mistry H, Hsieh G, Buhrlage SJ, Huang M, Park E, Cuny GD, Galinsky I, Stone RM, Gray NS, D'Andrea AD, Parmar K. Small-molecule inhibitors of USP1 target ID1 degradation in leukemic cells. Molecular Cancer Therapeutics. 12: 2651-62. PMID 24130053 DOI: 10.1158/1535-7163.Mct-13-0103-T |
0.348 |
|
| 2013 |
Johnson N, Johnson SF, Yao W, Li YC, Choi YE, Bernhardy AJ, Wang Y, Capelletti M, Sarosiek KA, Moreau LA, Chowdhury D, Wickramanayake A, Harrell MI, Liu JF, D'Andrea AD, et al. Stabilization of mutant BRCA1 protein confers PARP inhibitor and platinum resistance. Proceedings of the National Academy of Sciences of the United States of America. 110: 17041-6. PMID 24085845 DOI: 10.1073/Pnas.1305170110 |
0.402 |
|
| 2013 |
Adelman CA, Lolo RL, Birkbak NJ, Murina O, Matsuzaki K, Horejsi Z, Parmar K, Borel V, Skehel JM, Stamp G, D'Andrea A, Sartori AA, Swanton C, Boulton SJ. HELQ promotes RAD51 paralogue-dependent repair to avert germ cell loss and tumorigenesis. Nature. 502: 381-4. PMID 24005329 DOI: 10.1038/Nature12565 |
0.513 |
|
| 2013 |
Park E, Kim JM, Primack B, Weinstock DM, Moreau LA, Parmar K, D'Andrea AD. Inactivation of Uaf1 causes defective homologous recombination and early embryonic lethality in mice. Molecular and Cellular Biology. 33: 4360-70. PMID 24001775 DOI: 10.1128/Mcb.00870-13 |
0.401 |
|
| 2013 |
D'Andrea AD. BRCA1: a missing link in the Fanconi anemia/BRCA pathway. Cancer Discovery. 3: 376-8. PMID 23580280 DOI: 10.1158/2159-8290.Cd-13-0044 |
0.311 |
|
| 2013 |
Price BD, D'Andrea AD. Chromatin remodeling at DNA double-strand breaks. Cell. 152: 1344-54. PMID 23498941 DOI: 10.1016/J.Cell.2013.02.011 |
0.361 |
|
| 2013 |
O'Connor KW, Dejsuphong D, Park E, Nicolae CM, Kimmelman AC, D'Andrea AD, Moldovan GL. PARI overexpression promotes genomic instability and pancreatic tumorigenesis. Cancer Research. 73: 2529-39. PMID 23436799 DOI: 10.1158/0008-5472.Can-12-3313 |
0.483 |
|
| 2013 |
Russell N, Taylor T, Parmar K, D'Andrea AD, Brasher BB, Melandri FD. Characterization Of Full-Length, Recombinant Amsh, USP9x, and USP1: Clinically-Relevant Deubiquitinases Involved In Hematological Malignancies Blood. 122: 4224-4224. DOI: 10.1182/Blood.V122.21.4224.4224 |
0.331 |
|
| 2013 |
Mistry H, Hsieh G, Buhrlage S, Huang M, Park E, Cuny G, Galinsky I, Stone RM, Gray NS, Parmar K, D'Andrea AD. Small Molecule Inhibitors of USP1 Target ID1 Degradation in Leukemic Cells and Cause Cytotoxicity Blood. 122: 2906-2906. DOI: 10.1182/Blood.V122.21.2906.2906 |
0.366 |
|
| 2013 |
Johnson SF, Johnson N, Chi D, Primack B, D'Andrea AD, Lim E, Shapiro GI. Abstract 1788: The CDK inhibitor dinaciclib sensitizes triple-negative breast cancer cells to PARP inhibition. Cancer Research. 73: 1788-1788. DOI: 10.1158/1538-7445.Am2013-1788 |
0.405 |
|
| 2013 |
Kommajosyula N, Cao Y, Moreau L, D'Andrea A, Shapiro GI. Abstract 1787: Identification of factors governing sensitivity of NSCLC cell lines to inhibition of Poly (ADP-Ribose) Polymerase (PARP). Cancer Research. 73: 1787-1787. DOI: 10.1158/1538-7445.Am2013-1787 |
0.381 |
|
| 2013 |
O'Connor K, Dejsuphong D, D'Andrea A, Moldovan G. Abstract 1764: Overexpression of the DNA repair regulator PARI in pancreatic cancers promotes genomic instability and tumorigenesis. Cancer Research. 73: 1764-1764. DOI: 10.1158/1538-7445.Am2013-1764 |
0.472 |
|
| 2013 |
Cron KR, Zhu K, Kushwaha D, Hsieh G, Merzon D, Monahan J, Chen CC, D'Andrea A, Kozono D. Abstract 1583: Proteasome inhibition as a strategy for non-small cell lung carcinoma via inhibition of DNA double strand break repair. Cancer Research. 73: 1583-1583. DOI: 10.1158/1538-7445.Am2013-1583 |
0.412 |
|
| 2013 |
D'Andrea AD. Abstract CN05-02: Targeting the Fanconi anemia/BRCA pathway. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-Cn05-02 |
0.516 |
|
| 2013 |
Johnson N, Johnson SF, Wang Y, Bernhardy A, Yao W, Choi Y, Capelletti M, Sarosiek K, Moreau L, Chowdhury D, Liu J, D'Andrea A, Miron A, Wickramanayake A, Harrell M, et al. Abstract C74: Stabilization of mutant BRCA1 confers PARP inhibitor and platinum resistance. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-C74 |
0.409 |
|
| 2013 |
Kozono DE, Cron K, Kushwaha D, D'Andrea AD. Proteasome Inhibitors Block DNA Repair and Radiosensitize Non-Small Cell Lung Cancer International Journal of Radiation Oncology Biology Physics. 87. DOI: 10.1016/J.Ijrobp.2013.06.060 |
0.402 |
|
| 2012 |
Wojtaszek J, Lee CJ, D'Souza S, Minesinger B, Kim H, D'Andrea AD, Walker GC, Zhou P. Structural basis of Rev1-mediated assembly of a quaternary vertebrate translesion polymerase complex consisting of Rev1, heterodimeric polymerase (Pol) ζ, and Pol κ. The Journal of Biological Chemistry. 287: 33836-46. PMID 22859295 DOI: 10.1074/Jbc.M112.394841 |
0.422 |
|
| 2012 |
Moldovan GL, D'Andrea AD. To the rescue: the Fanconi anemia genome stability pathway salvages replication forks. Cancer Cell. 22: 5-6. PMID 22789533 DOI: 10.1016/J.Ccr.2012.06.006 |
0.397 |
|
| 2012 |
Kim H, D'Andrea AD. Regulation of DNA cross-link repair by the Fanconi anemia/BRCA pathway. Genes & Development. 26: 1393-408. PMID 22751496 DOI: 10.1101/Gad.195248.112 |
0.503 |
|
| 2012 |
Ceccaldi R, Parmar K, Mouly E, Delord M, Kim JM, Regairaz M, Pla M, Vasquez N, Zhang QS, Pondarre C, Peffault de Latour R, Gluckman E, Cavazzana-Calvo M, Leblanc T, Larghero J, et al. Bone marrow failure in Fanconi anemia is triggered by an exacerbated p53/p21 DNA damage response that impairs hematopoietic stem and progenitor cells. Cell Stem Cell. 11: 36-49. PMID 22683204 DOI: 10.1016/J.Stem.2012.05.013 |
0.407 |
|
| 2012 |
Jacquemont C, Simon JA, D'Andrea AD, Taniguchi T. Non-specific chemical inhibition of the Fanconi anemia pathway sensitizes cancer cells to cisplatin. Molecular Cancer. 11: 26. PMID 22537224 DOI: 10.1186/1476-4598-11-26 |
0.423 |
|
| 2012 |
Bunting SF, Callén E, Kozak ML, Kim JM, Wong N, López-Contreras AJ, Ludwig T, Baer R, Faryabi RB, Malhowski A, Chen HT, Fernandez-Capetillo O, D'Andrea A, Nussenzweig A. BRCA1 functions independently of homologous recombination in DNA interstrand crosslink repair. Molecular Cell. 46: 125-35. PMID 22445484 DOI: 10.1016/J.Molcel.2012.02.015 |
0.495 |
|
| 2012 |
Müller LU, Milsom MD, Harris CE, Vyas R, Brumme KM, Parmar K, Moreau LA, Schambach A, Park IH, London WB, Strait K, Schlaeger T, Devine AL, Grassman E, D'Andrea A, et al. Overcoming reprogramming resistance of Fanconi anemia cells. Blood. 119: 5449-57. PMID 22371882 DOI: 10.1182/Blood-2012-02-408674 |
0.458 |
|
| 2012 |
Kim H, Yang K, Dejsuphong D, D'Andrea AD. Regulation of Rev1 by the Fanconi anemia core complex. Nature Structural & Molecular Biology. 19: 164-70. PMID 22266823 DOI: 10.1038/Nsmb.2222 |
0.679 |
|
| 2012 |
Kee Y, Huang M, Chang S, Moreau LA, Park E, Smith PG, D'Andrea AD. Inhibition of the Nedd8 system sensitizes cells to DNA interstrand cross-linking agents. Molecular Cancer Research : McR. 10: 369-77. PMID 22219386 DOI: 10.1158/1541-7786.Mcr-11-0497 |
0.48 |
|
| 2012 |
Moldovan GL, Dejsuphong D, Petalcorin MI, Hofmann K, Takeda S, Boulton SJ, D'Andrea AD. Inhibition of homologous recombination by the PCNA-interacting protein PARI. Molecular Cell. 45: 75-86. PMID 22153967 DOI: 10.1016/J.Molcel.2011.11.010 |
0.466 |
|
| 2012 |
Grompe M, Postlethwait J, D'Andrea AD, Olson SB, Zhang Q, Bagby GC. Fanconi Anemia: Emerging Therapeutic Opportunities Blood. 120: SCI-1-SCI-1. DOI: 10.1182/Blood.V120.21.Sci-1.Sci-1 |
0.369 |
|
| 2012 |
Kommajosyula N, Moreau L, D'Andrea AD, Shapiro GI. Abstract 2540: Identification of factors governing sensitivity of NSCLC cell lines to inhibition of Poly (ADP-Ribose) Polymerase (PARP) Cancer Research. 72: 2540-2540. DOI: 10.1158/1538-7445.Am2012-2540 |
0.404 |
|
| 2012 |
Zhu K, Kushwaha D, Cron K, Hsieh G, Merzon D, Evans D, Ng K, Chen CC, D'Andrea AD, Kozono D. Abstract 1448: Whole genome RNAi screen identifies proteasome inhibition as a strategy for NSCLC radiosensitization Cancer Research. 72: 1448-1448. DOI: 10.1158/1538-7445.Am2012-1448 |
0.32 |
|
| 2011 |
Ayrapetov MK, Xu C, Sun Y, Zhu K, Parmar K, D'Andrea AD, Price BD. Activation of Hif1α by the prolylhydroxylase inhibitor dimethyoxalyglycine decreases radiosensitivity. Plos One. 6: e26064. PMID 22016813 DOI: 10.1371/Journal.Pone.0026064 |
0.393 |
|
| 2011 |
Huang M, Kennedy R, Ali AM, Moreau LA, Meetei AR, D'Andrea AD, Chen CC. Human MutS and FANCM complexes function as redundant DNA damage sensors in the Fanconi Anemia pathway. Dna Repair. 10: 1203-12. PMID 21975120 DOI: 10.1016/j.dnarep.2011.09.006 |
0.402 |
|
| 2011 |
Hendel A, Krijger PH, Diamant N, Goren Z, Langerak P, Kim J, Reissner T, Lee KY, Geacintov NE, Carell T, Myung K, Tateishi S, D'Andrea A, Jacobs H, Livneh Z. PCNA ubiquitination is important, but not essential for translesion DNA synthesis in mammalian cells. Plos Genetics. 7: e1002262. PMID 21931560 DOI: 10.1371/Journal.Pgen.1002262 |
0.486 |
|
| 2011 |
Yang K, Moldovan GL, Vinciguerra P, Murai J, Takeda S, D'Andrea AD. Regulation of the Fanconi anemia pathway by a SUMO-like delivery network. Genes & Development. 25: 1847-58. PMID 21896657 DOI: 10.1101/Gad.17020911 |
0.665 |
|
| 2011 |
Vaezi A, Wang X, Buch S, Gooding W, Wang L, Seethala RR, Weaver DT, D'Andrea AD, Argiris A, Romkes M, Niedernhofer LJ, Grandis JR. XPF expression correlates with clinical outcome in squamous cell carcinoma of the head and neck. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 5513-22. PMID 21737503 DOI: 10.1158/1078-0432.Ccr-11-0086 |
0.408 |
|
| 2011 |
Johnson N, Li YC, Walton ZE, Cheng KA, Li D, Rodig SJ, Moreau LA, Unitt C, Bronson RT, Thomas HD, Newell DR, D'Andrea AD, Curtin NJ, Wong KK, Shapiro GI. Compromised CDK1 activity sensitizes BRCA-proficient cancers to PARP inhibition. Nature Medicine. 17: 875-82. PMID 21706030 DOI: 10.1038/Nm.2377 |
0.398 |
|
| 2011 |
Kao WH, Riker AI, Kushwaha DS, Ng K, Enkemann SA, Jove R, Buettner R, Zinn PO, Sánchez NP, Villa JL, D'Andrea AD, Sánchez JL, Kennedy RD, Chen CC, Matta JL. Upregulation of Fanconi anemia DNA repair genes in melanoma compared with non-melanoma skin cancer. The Journal of Investigative Dermatology. 131: 2139-42. PMID 21697891 DOI: 10.1038/Jid.2011.181 |
0.392 |
|
| 2011 |
Moldovan GL, D'Andrea AD. DNA damage discrimination at stalled replication forks by the Rad5 homologs HLTF and SHPRH. Molecular Cell. 42: 141-3. PMID 21504827 DOI: 10.1016/J.Molcel.2011.03.018 |
0.439 |
|
| 2011 |
Murai J, Yang K, Dejsuphong D, Hirota K, Takeda S, D'Andrea AD. The USP1/UAF1 complex promotes double-strand break repair through homologous recombination. Molecular and Cellular Biology. 31: 2462-9. PMID 21482670 DOI: 10.1128/Mcb.05058-11 |
0.703 |
|
| 2011 |
Mueller L, Milsom MD, Harris C, Vyas R, Brumme K, Parmar K, Schambach A, Grassman E, Park I, Wendy L, Strait K, Schlaeger T, Devine AL, D'Andrea AD, Daley GQ, et al. Gene-Correction Rescues Reprogramming of Fanconi Anemia Fibroblasts and Enables Hematopoietic Differentiation of FA Induced Pluripotent Stem Cells in Vitro and In Vivo Blood. 118: 672-672. DOI: 10.1182/Blood.V118.21.672.672 |
0.379 |
|
| 2011 |
Yang K, Moldovan G, Vinciguerra P, Murai J, Takeda S, D'Andrea AD. Abstract PR4: Regulation of the Fanconi anemia pathway by a SUMO-like delivery network Cancer Research. 71. DOI: 10.1158/1538-7445.Fbcr11-Pr4 |
0.678 |
|
| 2011 |
D'Andrea AD. Abstract IA9: Targeting the Fanconi anemia/BRCA pathway in cancer therapy Cancer Research. 71. DOI: 10.1158/1538-7445.Fbcr11-Ia9 |
0.519 |
|
| 2011 |
Johnson N, Li Y, Walton Z, Li D, Moreau L, Rodig SJ, D'Andrea AD, Thomas H, Newell DR, Curtin NJ, Wong KK, Shapiro GI. Abstract 2979: Combined cdk1 and PARP inhibition results in tumor regression in a KrasG12D p53L/L murine lung adenocarcinoma model Cancer Research. 71: 2979-2979. DOI: 10.1158/1538-7445.Am2011-2979 |
0.357 |
|
| 2011 |
Kang J, D'Andrea A, Kozono D. Abstract 2751: Fanconi anemia pathway and DNA repair-based prognostic signatures in ovarian cancer Epidemiology. 71: 2751-2751. DOI: 10.1158/1538-7445.Am2011-2751 |
0.438 |
|
| 2011 |
D'Andrea AD. Abstract CN05-02: Targeting the Fanconi anemia/BRCA pathway in cancer therapy. Molecular Cancer Therapeutics. 10. DOI: 10.1158/1535-7163.Targ-11-Cn05-02 |
0.519 |
|
| 2010 |
Alexander BM, Sprott K, Farrow DA, Wang X, D'Andrea AD, Schnitt SJ, Collins LC, Weaver DT, Garber JE. DNA repair protein biomarkers associated with time to recurrence in triple-negative breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 5796-804. PMID 21138871 DOI: 10.1158/1078-0432.Ccr-10-0292 |
0.383 |
|
| 2010 |
D'Andrea AD. Targeting DNA repair pathways in AML. Best Practice & Research. Clinical Haematology. 23: 469-73. PMID 21130409 DOI: 10.1016/j.beha.2010.09.005 |
0.393 |
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| 2010 |
Vinciguerra P, Godinho SA, Parmar K, Pellman D, D'Andrea AD. Cytokinesis failure occurs in Fanconi anemia pathway-deficient murine and human bone marrow hematopoietic cells. The Journal of Clinical Investigation. 120: 3834-42. PMID 20921626 DOI: 10.1172/Jci43391 |
0.312 |
|
| 2010 |
Kee Y, D'Andrea AD. Expanded roles of the Fanconi anemia pathway in preserving genomic stability. Genes & Development. 24: 1680-94. PMID 20713514 DOI: 10.1101/Gad.1955310 |
0.499 |
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| 2010 |
Huang M, D'Andrea AD. A new nuclease member of the FAN club. Nature Structural & Molecular Biology. 17: 926-8. PMID 20683477 DOI: 10.1038/Nsmb0810-926 |
0.489 |
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| 2010 |
Huang M, Kim JM, Shiotani B, Yang K, Zou L, D'Andrea AD. The FANCM/FAAP24 complex is required for the DNA interstrand crosslink-induced checkpoint response. Molecular Cell. 39: 259-68. PMID 20670894 DOI: 10.1016/J.Molcel.2010.07.005 |
0.685 |
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| 2010 |
Nitta M, Kozono D, Kennedy R, Stommel J, Ng K, Zinn PO, Kushwaha D, Kesari S, Inda MM, Wykosky J, Furnari F, Hoadley KA, Chin L, DePinho RA, Cavenee WK, et al. Targeting EGFR induced oxidative stress by PARP1 inhibition in glioblastoma therapy. Plos One. 5: e10767. PMID 20532243 DOI: 10.1371/Journal.Pone.0010767 |
0.387 |
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| 2010 |
Parmar K, Kim J, Sykes SM, Shimamura A, Stuckert P, Zhu K, Hamilton A, Deloach MK, Kutok JL, Akashi K, Gilliland DG, D'andrea A. Hematopoietic stem cell defects in mice with deficiency of Fancd2 or Usp1. Stem Cells (Dayton, Ohio). 28: 1186-95. PMID 20506303 DOI: 10.1002/Stem.437 |
0.304 |
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| 2010 |
D'Andrea AD. Susceptibility pathways in Fanconi's anemia and breast cancer. The New England Journal of Medicine. 362: 1909-19. PMID 20484397 DOI: 10.1056/Nejmra0809889 |
0.451 |
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| 2010 |
Yang K, Moldovan GL, D'Andrea AD. RAD18-dependent recruitment of SNM1A to DNA repair complexes by a ubiquitin-binding zinc finger. The Journal of Biological Chemistry. 285: 19085-91. PMID 20385554 DOI: 10.1074/Jbc.M109.100032 |
0.672 |
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| 2010 |
Kee Y, Yang K, Cohn MA, Haas W, Gygi SP, D'Andrea AD. WDR20 regulates activity of the USP12 x UAF1 deubiquitinating enzyme complex. The Journal of Biological Chemistry. 285: 11252-7. PMID 20147737 DOI: 10.1074/Jbc.M109.095141 |
0.609 |
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| 2010 |
Lee KY, Yang K, Cohn MA, Sikdar N, D'Andrea AD, Myung K. Human ELG1 regulates the level of ubiquitinated proliferating cell nuclear antigen (PCNA) through Its interactions with PCNA and USP1. The Journal of Biological Chemistry. 285: 10362-9. PMID 20147293 DOI: 10.1074/Jbc.M109.092544 |
0.637 |
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| 2010 |
Moldovan GL, Madhavan MV, Mirchandani KD, McCaffrey RM, Vinciguerra P, D'Andrea AD. DNA polymerase POLN participates in cross-link repair and homologous recombination. Molecular and Cellular Biology. 30: 1088-96. PMID 19995904 DOI: 10.1128/Mcb.01124-09 |
0.804 |
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| 2010 |
Vaezi AE, Wang X, Buch SC, Farrow D, Weaver DT, D'Andrea AD, Seethala RR, Romkes M, Niedernhofer LJ, Grandis JR. Use of XPF expression in tumors and XPF single nucleotide polymorphisms to predict clinical outcome in head and neck cancer. Journal of Clinical Oncology. 28: 5520-5520. DOI: 10.1200/Jco.2010.28.15_Suppl.5520 |
0.329 |
|
| 2010 |
Parmar K, Vinciguerra P, Godinho S, Hamilton A, Pellman D, D'Andrea AD. Cytokinesis Failure In Fanconi Anemia Pathway Deficient Hematopoietic Cells Blood. 116: 878-878. DOI: 10.1182/Blood.V116.21.878.878 |
0.404 |
|
| 2010 |
Mueller L, Milsom MD, Brumme K, Harris C, Parmar K, Zhu K, Wendy L, Strait K, D'Andrea AD, Daley GQ, Williams DA. Mechanisms of Resistance to Reprogramming of Cells Defective In the Fanconi Anemia DNA Repair Pathway Blood. 116: 196-196. DOI: 10.1182/Blood.V116.21.196.196 |
0.438 |
|
| 2010 |
Johnson N, Li Y, Moreau LA, Thomas HD, Newell DR, D'andrea AD, Curtin NJ, Shapiro GI. Abstract 3882: Compromised Cdk1 activity sensitizes BRCA-proficient cancer cells to inhibition of Poly(ADP-ribose) polymerase Cancer Research. 70: 3882-3882. DOI: 10.1158/1538-7445.Am10-3882 |
0.441 |
|
| 2010 |
Kozono D, Ng K, Hsieh G, Merzon D, Nitta M, Zinn PO, Kahle K, Elledge S, D'Andrea A, Chen CC. Abstract 1318: Proteasome and Fanconi Anemia/BRCA pathways as prognostic determinants of glioblastoma response to radiation and temozolomide: a proposed clinical trial Cancer Research. 70: 1318-1318. DOI: 10.1158/1538-7445.Am10-1318 |
0.363 |
|
| 2009 |
Vinciguerra P, D'Andrea AD. FANCM: A landing pad for the Fanconi Anemia and Bloom's Syndrome complexes. Molecular Cell. 36: 916-7. PMID 20064455 DOI: 10.1016/J.Molcel.2009.12.007 |
0.357 |
|
| 2009 |
Moldovan GL, D'Andrea AD. FANCD2 hurdles the DNA interstrand crosslink. Cell. 139: 1222-4. PMID 20064367 DOI: 10.1016/J.Cell.2009.12.006 |
0.435 |
|
| 2009 |
Bhagwat N, Olsen AL, Wang AT, Hanada K, Stuckert P, Kanaar R, D'Andrea A, Niedernhofer LJ, McHugh PJ. XPF-ERCC1 participates in the Fanconi anemia pathway of cross-link repair. Molecular and Cellular Biology. 29: 6427-37. PMID 19805513 DOI: 10.1128/Mcb.00086-09 |
0.511 |
|
| 2009 |
Moldovan GL, D'Andrea AD. How the fanconi anemia pathway guards the genome. Annual Review of Genetics. 43: 223-49. PMID 19686080 DOI: 10.1146/Annurev-Genet-102108-134222 |
0.512 |
|
| 2009 |
Johnson N, Cai D, Kennedy RD, Pathania S, Arora M, Li YC, D'Andrea AD, Parvin JD, Shapiro GI. Cdk1 participates in BRCA1-dependent S phase checkpoint control in response to DNA damage. Molecular Cell. 35: 327-39. PMID 19683496 DOI: 10.1016/J.Molcel.2009.06.036 |
0.47 |
|
| 2009 |
Chen CC, Kennedy RD, Sidi S, Look AT, D'Andrea A. CHK1 inhibition as a strategy for targeting Fanconi Anemia (FA) DNA repair pathway deficient tumors. Molecular Cancer. 8: 24. PMID 19371427 DOI: 10.1186/1476-4598-8-24 |
0.481 |
|
| 2009 |
Kee Y, Kim JM, D'Andrea AD, D'Andrea A. Regulated degradation of FANCM in the Fanconi anemia pathway during mitosis. Genes & Development. 23: 555-60. PMID 19270156 DOI: 10.1101/Gad.1761309 |
0.452 |
|
| 2009 |
Kim JM, Parmar K, Huang M, Weinstock DM, Ruit CA, Kutok JL, D'Andrea AD. Inactivation of murine Usp1 results in genomic instability and a Fanconi anemia phenotype. Developmental Cell. 16: 314-20. PMID 19217432 DOI: 10.1016/J.Devcel.2009.01.001 |
0.512 |
|
| 2009 |
Cohn MA, Kee Y, Haas W, Gygi SP, D'Andrea AD. UAF1 is a subunit of multiple deubiquitinating enzyme complexes. The Journal of Biological Chemistry. 284: 5343-51. PMID 19075014 DOI: 10.1074/Jbc.M808430200 |
0.351 |
|
| 2009 |
Vinciguerra P, Godinho S, Parmar K, Pellman D, D'Andrea A. Cytokinesis Failure in Fanconi Anemia Pathway Deficient Murine Hematopoietic Stem Cells. Blood. 114: 495-495. DOI: 10.1182/Blood.V114.22.495.495 |
0.463 |
|
| 2009 |
Alexander B, Sprott K, Wang X, D'Andrea A, Schnitt S, Collins L, Weaver D, Garber J. DNA repair protein biomarkers in triple negative breast cancer. Cancer Research. 69: 1064. DOI: 10.1158/0008-5472.Sabcs-1064 |
0.38 |
|
| 2008 |
Cohn MA, D'Andrea AD. Chromatin recruitment of DNA repair proteins: lessons from the fanconi anemia and double-strand break repair pathways. Molecular Cell. 32: 306-12. PMID 18995829 DOI: 10.1016/J.Molcel.2008.10.009 |
0.499 |
|
| 2008 |
Mirchandani KD, McCaffrey RM, D'Andrea AD. The Fanconi anemia core complex is required for efficient point mutagenesis and Rev1 foci assembly. Dna Repair. 7: 902-11. PMID 18448394 DOI: 10.1016/J.Dnarep.2008.03.001 |
0.815 |
|
| 2008 |
Kim JM, Kee Y, Gurtan A, D'Andrea AD. Cell cycle-dependent chromatin loading of the Fanconi anemia core complex by FANCM/FAAP24. Blood. 111: 5215-22. PMID 18174376 DOI: 10.1182/Blood-2007-09-113092 |
0.804 |
|
| 2008 |
Alexander B, Glickman J, Wang X, Weaver D, D'Andrea A, Mamon H. DNA Repair Biomarkers in Rectal Cancer International Journal of Radiation Oncology*Biology*Physics. 72: S248. DOI: 10.1016/J.Ijrobp.2008.06.639 |
0.424 |
|
| 2007 |
Cohn MA, Kowal P, Yang K, Haas W, Huang TT, Gygi SP, D'Andrea AD. A UAF1-containing multisubunit protein complex regulates the Fanconi anemia pathway. Molecular Cell. 28: 786-97. PMID 18082604 DOI: 10.1016/J.Molcel.2007.09.031 |
0.668 |
|
| 2007 |
Kennedy RD, Chen CC, Stuckert P, Archila EM, De la Vega MA, Moreau LA, Shimamura A, D'Andrea AD. Fanconi anemia pathway-deficient tumor cells are hypersensitive to inhibition of ataxia telangiectasia mutated. The Journal of Clinical Investigation. 117: 1440-9. PMID 17431503 DOI: 10.1172/JCI31245 |
0.358 |
|
| 2007 |
Smogorzewska A, Matsuoka S, Vinciguerra P, McDonald ER, Hurov KE, Luo J, Ballif BA, Gygi SP, Hofmann K, D'Andrea AD, Elledge SJ. Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair. Cell. 129: 289-301. PMID 17412408 DOI: 10.1016/J.Cell.2007.03.009 |
0.504 |
|
| 2007 |
Wang X, Kennedy RD, Ray K, Stuckert P, Ellenberger T, D'Andrea AD. Chk1-mediated phosphorylation of FANCE is required for the Fanconi anemia/BRCA pathway Molecular and Cellular Biology. 27: 3098-3108. PMID 17296736 DOI: 10.1128/Mcb.02357-06 |
0.512 |
|
| 2007 |
Chen CC, Taniguchi T, D'Andrea A. The Fanconi anemia (FA) pathway confers glioma resistance to DNA alkylating agents Journal of Molecular Medicine. 85: 497-509. PMID 17221219 DOI: 10.1007/S00109-006-0153-2 |
0.347 |
|
| 2007 |
Kowal P, Gurtan AM, Stuckert P, D'Andrea AD, Ellenberger T. Structural determinants of human FANCF protein that function in the assembly of a DNA damage signaling complex Journal of Biological Chemistry. 282: 2047-2055. PMID 17082180 DOI: 10.1074/Jbc.M608356200 |
0.802 |
|
| 2007 |
Chen CC, D'Andrea A. Targeting Epidermal Growth Factor Receptor Overexpression in Glioblastoma Multiforme by Inhibition of DNA Repair Neurosurgery. 61: 219-220. DOI: 10.1227/01.Neu.0000279954.96762.18 |
0.372 |
|
| 2007 |
Kennedy RD, Stuckert P, Archila E, De LaVega M, Chen C, Moreau L, D'Andrea A. Sensitivity of tumor cells deficient in the fanconi anemia pathway to inhibition of ataxia telangiectasia mutated (ATM) Journal of Clinical Oncology. 25: 10509-10509. DOI: 10.1200/Jco.2007.25.18_Suppl.10509 |
0.482 |
|
| 2006 |
Huang TT, D'Andrea AD. HAUSP hunting the FOX(O) Nature Cell Biology. 8: 1043-1045. PMID 17013413 DOI: 10.1038/Ncb1006-1043 |
0.301 |
|
| 2006 |
Ho GP, Margossian S, Taniguchi T, D'Andrea AD. Phosphorylation of FANCD2 on two novel sites is required for mitomycin C resistance. Molecular and Cellular Biology. 26: 7005-15. PMID 16943440 DOI: 10.1128/Mcb.02018-05 |
0.427 |
|
| 2006 |
Machida YJ, Machida Y, Chen Y, Gurtan AM, Kupfer GM, D'Andrea AD, Dutta A. UBE2T is the E2 in the Fanconi anemia pathway and undergoes negative autoregulation. Molecular Cell. 23: 589-96. PMID 16916645 DOI: 10.1016/J.Molcel.2006.06.024 |
0.815 |
|
| 2006 |
Kennedy RD, D'Andrea AD. DNA repair pathways in clinical practice: lessons from pediatric cancer susceptibility syndromes. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 24: 3799-808. PMID 16896009 DOI: 10.1200/Jco.2005.05.4171 |
0.477 |
|
| 2006 |
Mirchandani KD, D'Andrea AD. The Fanconi anemia/BRCA pathway: a coordinator of cross-link repair. Experimental Cell Research. 312: 2647-53. PMID 16859679 DOI: 10.1016/J.Yexcr.2006.06.014 |
0.806 |
|
| 2006 |
Gurtan AM, D'Andrea AD. Dedicated to the core: understanding the Fanconi anemia complex. Dna Repair. 5: 1119-25. PMID 16784902 DOI: 10.1016/J.Dnarep.2006.05.009 |
0.821 |
|
| 2006 |
Chirnomas D, Taniguchi T, de la Vega M, Vaidya AP, Vasserman M, Hartman AR, Kennedy R, Foster R, Mahoney J, Seiden MV, D'Andrea AD. Chemosensitization to cisplatin by inhibitors of the Fanconi anemia/BRCA pathway. Molecular Cancer Therapeutics. 5: 952-61. PMID 16648566 DOI: 10.1158/1535-7163.Mct-05-0493 |
0.433 |
|
| 2006 |
Huang TT, D'Andrea AD. Regulation of DNA repair by ubiquitylation. Nature Reviews. Molecular Cell Biology. 7: 323-34. PMID 16633336 DOI: 10.1038/Nrm1908 |
0.497 |
|
| 2006 |
Huang TT, Nijman SM, Mirchandani KD, Galardy PJ, Cohn MA, Haas W, Gygi SP, Ploegh HL, Bernards R, D'Andrea AD. Regulation of monoubiquitinated PCNA by DUB autocleavage. Nature Cell Biology. 8: 339-47. PMID 16531995 DOI: 10.1038/Ncb1378 |
0.795 |
|
| 2006 |
Taniguchi T, D'Andrea AD. Molecular pathogenesis of Fanconi anemia: recent progress. Blood. 107: 4223-33. PMID 16493006 DOI: 10.1182/Blood-2005-10-4240 |
0.484 |
|
| 2006 |
Andreassen PR, Ho GP, D'Andrea AD. DNA damage responses and their many interactions with the replication fork. Carcinogenesis. 27: 883-92. PMID 16490739 DOI: 10.1093/Carcin/Bgi319 |
0.47 |
|
| 2006 |
Gurtan AM, Stuckert P, D'Andrea AD. The WD40 repeats of FANCL are required for Fanconi anemia core complex assembly. The Journal of Biological Chemistry. 281: 10896-905. PMID 16474167 DOI: 10.1074/Jbc.M511411200 |
0.788 |
|
| 2006 |
Mankad A, Taniguchi T, Cox B, Akkari Y, Rathbun RK, Lucas L, Bagby G, Olson S, D'Andrea A, Grompe M. Natural gene therapy in monozygotic twins with Fanconi anemia. Blood. 107: 3084-90. PMID 16397136 DOI: 10.1182/Blood-2005-07-2638 |
0.341 |
|
| 2006 |
Howlett NG, Scuric Z, D'Andrea AD, Schiestl RH. Impaired DNA double strand break repair in cells from Nijmegen breakage syndrome patients. Dna Repair. 5: 251-7. PMID 16309973 DOI: 10.1016/J.Dnarep.2005.10.004 |
0.387 |
|
| 2005 |
Kennedy RD, D'Andrea AD. The Fanconi Anemia/BRCA pathway: new faces in the crowd. Genes & Development. 19: 2925-40. PMID 16357213 DOI: 10.1101/Gad.1370505 |
0.495 |
|
| 2005 |
Park WH, Margossian S, Horwitz AA, Simons AM, D'Andrea AD, Parvin JD. Direct DNA binding activity of the Fanconi anemia D2 protein. The Journal of Biological Chemistry. 280: 23593-8. PMID 15849361 DOI: 10.1074/Jbc.M503730200 |
0.45 |
|
| 2005 |
Nijman SM, Huang TT, Dirac AM, Brummelkamp TR, Kerkhoven RM, D'Andrea AD, Bernards R. The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway. Molecular Cell. 17: 331-9. PMID 15694335 DOI: 10.1016/J.Molcel.2005.01.008 |
0.517 |
|
| 2005 |
Howlett NG, Taniguchi T, Durkin SG, D'Andrea AD, Glover TW. The Fanconi anemia pathway is required for the DNA replication stress response and for the regulation of common fragile site stability. Human Molecular Genetics. 14: 693-701. PMID 15661754 DOI: 10.1093/Hmg/Ddi065 |
0.506 |
|
| 2005 |
Nakanishi K, Yang YG, Pierce AJ, Taniguchi T, Digweed M, D'Andrea AD, Wang ZQ, Jasin M. Human Fanconi anemia monoubiquitination pathway promotes homologous DNA repair. Proceedings of the National Academy of Sciences of the United States of America. 102: 1110-5. PMID 15650050 DOI: 10.1073/Pnas.0407796102 |
0.527 |
|
| 2005 |
New HV, Cale CM, Tischkowitz M, Jones A, Telfer P, Veys P, D'Andrea A, Mathew CG, Hann I. Nijmegen breakage syndrome diagnosed as fanconi anaemia Pediatric Blood and Cancer. 44: 494-499. PMID 15593232 DOI: 10.1002/Pbc.20271 |
0.372 |
|
| 2005 |
Montes de Oca R, Andreassen PR, Margossian SP, Gregory RC, Taniguchi T, Wang X, Houghtaling S, Grompe M, D'Andrea AD. Regulated interaction of the Fanconi anemia protein, FANCD2, with chromatin. Blood. 105: 1003-9. PMID 15454491 DOI: 10.1182/Blood-2003-11-3997 |
0.406 |
|
| 2005 |
Soulier J, Leblanc T, Larghero J, Dastot H, Shimamura A, Guardiola P, Esperou H, Ferry C, Jubert C, Feugeas JP, Henri A, Toubert A, Socié G, Baruchel A, Sigaux F, et al. Detection of somatic mosaicism and classification of Fanconi anemia patients by analysis of the FA/BRCA pathway. Blood. 105: 1329-36. PMID 15383454 DOI: 10.1182/Blood-2004-05-1852 |
0.361 |
|
| 2004 |
Andreassen PR, D'Andrea AD, Taniguchi T. ATR couples FANCD2 monoubiquitination to the DNA-damage response. Genes & Development. 18: 1958-63. PMID 15314022 DOI: 10.1101/Gad.1196104 |
0.47 |
|
| 2004 |
Wang X, D'Andrea AD. The interplay of Fanconi anemia proteins in the DNA damage response. Dna Repair. 3: 1063-9. PMID 15279794 DOI: 10.1016/j.dnarep.2004.04.005 |
0.376 |
|
| 2004 |
Wang X, Andreassen PR, D'Andrea AD. Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin. Molecular and Cellular Biology. 24: 5850-62. PMID 15199141 DOI: 10.1128/Mcb.24.13.5850-5862.2004 |
0.495 |
|
| 2004 |
Hirsch B, Shimamura A, Moreau L, Baldinger S, Hag-alshiekh M, Bostrom B, Sencer S, D'Andrea AD. Association of biallelic BRCA2/FANCD1 mutations with spontaneous chromosomal instability and solid tumors of childhood. Blood. 103: 2554-9. PMID 14670928 DOI: 10.1182/Blood-2003-06-1970 |
0.303 |
|
| 2003 |
Liu TX, Howlett NG, Deng M, Langenau DM, Hsu K, Rhodes J, Kanki JP, D'Andrea AD, Look AT. Knockdown of zebrafish Fancd2 causes developmental abnormalities via p53-dependent apoptosis. Developmental Cell. 5: 903-14. PMID 14667412 DOI: 10.1016/S1534-5807(03)00339-3 |
0.367 |
|
| 2003 |
Tischkowitz M, Ameziane N, Waisfisz Q, De Winter JP, Harris R, Taniguchi T, D'Andrea A, Hodgson SV, Mathew CG, Joenje H. Bi-allelic silencing of the Fanconi anaemia gene FANCF in acute myeloid leukaemia. British Journal of Haematology. 123: 469-71. PMID 14617007 DOI: 10.1046/J.1365-2141.2003.04640.X |
0.32 |
|
| 2003 |
Shimamura A, D'Andrea AD. Subtyping of Fanconi anemia patients: implications for clinical management. Blood. 102: 3459. PMID 14568911 DOI: 10.1182/Blood-2003-04-1297 |
0.306 |
|
| 2003 |
Jin S, Mao H, Schnepp RW, Sykes SM, Silva AC, D'Andrea AD, Hua X. Menin associates with FANCD2, a protein involved in repair of DNA damage. Cancer Research. 63: 4204-10. PMID 12874027 |
0.352 |
|
| 2003 |
Taniguchi T, Tischkowitz M, Ameziane N, Hodgson SV, Mathew CG, Joenje H, Mok SC, D'Andrea AD. Disruption of the Fanconi anemia-BRCA pathway in cisplatin-sensitive ovarian tumors. Nature Medicine. 9: 568-74. PMID 12692539 DOI: 10.1038/Nm852 |
0.347 |
|
| 2003 |
D'Andrea AD, Grompe M. The Fanconi anaemia/BRCA pathway. Nature Reviews. Cancer. 3: 23-34. PMID 12509764 DOI: 10.1038/Nrc970 |
0.502 |
|
| 2003 |
Gregory RC, Taniguchi T, D'Andrea AD. Regulation of the Fanconi anemia pathway by monoubiquitination. Seminars in Cancer Biology. 13: 77-82. PMID 12507559 DOI: 10.1016/S1044-579X(02)00102-5 |
0.398 |
|
| 2002 |
Nakanishi K, Taniguchi T, Ranganathan V, New HV, Moreau LA, Stotsky M, Mathew CG, Kastan MB, Weaver DT, D'Andrea AD. Interaction of FANCD2 and NBS1 in the DNA damage response. Nature Cell Biology. 4: 913-20. PMID 12447395 DOI: 10.1038/Ncb879 |
0.421 |
|
| 2002 |
Adachi D, Oda T, Yagasaki H, Nakasato K, Taniguchi T, D'Andrea AD, Asano S, Yamashita T. Heterogeneous activation of the Fanconi anemia pathway by patient-derived FANCA mutants. Human Molecular Genetics. 11: 3125-34. PMID 12444097 DOI: 10.1093/Hmg/11.25.3125 |
0.459 |
|
| 2002 |
Shimamura A, Montes de Oca R, Svenson JL, Haining N, Moreau LA, Nathan DG, D'Andrea AD. A novel diagnostic screen for defects in the Fanconi anemia pathway. Blood. 100: 4649-54. PMID 12393398 DOI: 10.1182/Blood-2002-05-1399 |
0.317 |
|
| 2002 |
Folias A, Matkovic M, Bruun D, Reid S, Hejna J, Grompe M, D'Andrea A, Moses R. BRCA1 interacts directly with the Fanconi anemia protein FANCA Human Molecular Genetics. 11: 2591-2597. PMID 12354784 DOI: 10.1093/Hmg/11.21.2591 |
0.454 |
|
| 2002 |
Taniguchi T, D'Andrea AD. The Fanconi anemia protein, FANCE, promotes the nuclear accumulation of FANCC. Blood. 100: 2457-62. PMID 12239156 DOI: 10.1182/Blood-2002-03-0860 |
0.423 |
|
| 2002 |
Taniguchi T, Garcia-Higuera I, Andreassen PR, Gregory RC, Grompe M, D'Andrea AD. S-phase-specific interaction of the Fanconi anemia protein, FANCD2, with BRCA1 and RAD51. Blood. 100: 2414-20. PMID 12239151 DOI: 10.1182/Blood-2002-01-0278 |
0.478 |
|
| 2002 |
Taniguchi T, Garcia-Higuera I, Xu B, Andreassen PR, Gregory RC, Kim ST, Lane WS, Kastan MB, D'Andrea AD. Convergence of the fanconi anemia and ataxia telangiectasia signaling pathways. Cell. 109: 459-72. PMID 12086603 DOI: 10.1016/S0092-8674(02)00747-X |
0.389 |
|
| 2002 |
Howlett NG, Taniguchi T, Olson S, Cox B, Waisfisz Q, De Die-Smulders C, Persky N, Grompe M, Joenje H, Pals G, Ikeda H, Fox EA, D'Andrea AD. Biallelic inactivation of BRCA2 in Fanconi anemia. Science (New York, N.Y.). 297: 606-9. PMID 12065746 DOI: 10.1126/Science.1073834 |
0.372 |
|
| 2002 |
Yagasaki H, Adachi D, Oda T, Garcia-Higuera I, Tetteh N, D'Andrea AD, Futaki M, Asano S, Yamashita T. A cytoplasmic serine protein kinase binds and may regulate the Fanconi anemia protein FANCA. Blood. 98: 3650-7. PMID 11739169 DOI: 10.1182/Blood.V98.13.3650 |
0.406 |
|
| 2002 |
D'Andrea AD. Cellular function of the Fanconi anemia pathway. Nature Medicine. 7: 1259-60. PMID 11726938 DOI: 10.1038/Nm1201-1259A |
0.313 |
|
| 2001 |
Wilson JB, Johnson MA, Stuckert AP, Trueman KL, May S, Bryant PE, Meyn RE, D'Andrea AD, Jones NJ. The Chinese hamster FANCG/XRCC9 mutant NM3 fails to express the monoubiquitinated form of the FANCD2 protein, is hypersensitive to a range of DNA damaging agents and exhibits a normal level of spontaneous sister chromatid exchange. Carcinogenesis. 22: 1939-46. PMID 11751423 DOI: 10.1093/Carcin/22.12.1939 |
0.488 |
|
| 2001 |
Siddique MA, Nakanishi K, Taniguchi T, Grompe M, D'Andrea AD. Function of the Fanconi anemia pathway in Fanconi anemia complementation group F and D1 cells. Experimental Hematology. 29: 1448-55. PMID 11750104 DOI: 10.1016/S0301-472X(01)00754-8 |
0.391 |
|
| 2001 |
Akkari YM, Bateman RL, Reifsteck CA, D'Andrea AD, Olson SB, Grompe M. The 4N cell cycle delay in Fanconi anemia reflects growth arrest in late S phase. Molecular Genetics and Metabolism. 74: 403-12. PMID 11749045 DOI: 10.1006/Mgme.2001.3259 |
0.451 |
|
| 2001 |
Yang Y, Kuang Y, Montes De Oca R, Hays T, Moreau L, Lu N, Seed B, D'Andrea AD. Targeted disruption of the murine Fanconi anemia gene, Fancg/Xrcc9. Blood. 98: 3435-40. PMID 11719385 DOI: 10.1182/Blood.V98.12.3435 |
0.357 |
|
| 2001 |
Migone T, Humbert M, Rascle A, Sanden D, D'Andrea A, Johnston JA. The deubiquitinating enzyme DUB-2 prolongs cytokine-induced signal transducers and activators of transcription activation and suppresses apoptosis following cytokine withdrawal Blood. 98: 1935-1941. PMID 11535532 DOI: 10.1182/Blood.V98.6.1935 |
0.302 |
|
| 2001 |
Baek KH, Mondoux MA, Jaster R, Fire-Levin E, D'Andrea AD. DUB-2A, a new member of the DUB subfamily of hematopoietic deubiquitinating enzymes. Blood. 98: 636-42. PMID 11468161 DOI: 10.1182/Blood.V98.3.636 |
0.32 |
|
| 2001 |
Nakanishi K, Moran A, Hays T, Kuang Y, Fox E, Garneau D, Montes de Oca R, Grompe M, D'Andrea AD. Functional analysis of patient-derived mutations in the Fanconi anemia gene, FANCG/XRCC9. Experimental Hematology. 29: 842-9. PMID 11438206 DOI: 10.1016/S0301-472X(01)00663-4 |
0.345 |
|
| 2001 |
Garcia-Higuera I, Taniguchi T, Ganesan S, Meyn MS, Timmers C, Hejna J, Grompe M, D'Andrea AD. Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway. Molecular Cell. 7: 249-62. PMID 11239454 DOI: 10.1016/S1097-2765(01)00173-3 |
0.491 |
|
| 2001 |
Timmers C, Taniguchi T, Hejna J, Reifsteck C, Lucas L, Bruun D, Thayer M, Cox B, Olson S, D'Andrea AD, Moses R, Grompe M. Positional cloning of a novel Fanconi anemia gene, FANCD2. Molecular Cell. 7: 241-8. PMID 11239453 DOI: 10.1016/S1097-2765(01)00172-1 |
0.344 |
|
| 2001 |
Noll M, Bateman RL, D'Andrea AD, Grompe M. Preclinical protocol for in vivo selection of hematopoietic stem cells corrected by gene therapy in Fanconi anemia group C. Molecular Therapy : the Journal of the American Society of Gene Therapy. 3: 14-23. PMID 11162306 DOI: 10.1006/Mthe.2000.0226 |
0.314 |
|
| 2000 |
Garcia-Higuera I, Kuang Y, Denham J, D'Andrea AD. The Fanconi anemia proteins FANCA and FANCG stabilize each other and promote the nuclear accumulation of the Fanconi anemia complex Blood. 96: 3224-3230. DOI: 10.1182/Blood.V96.9.3224.H8003224_3224_3230 |
0.434 |
|
| 2000 |
Kuang Y, Garcia-Higuera I, Moran A, Mondoux M, Digweed M, D'Andrea AD. Carboxy terminal region of the Fanconi anemia protein, FANCG/XRCC9, is required for functional activity Blood. 96: 1625-1632. DOI: 10.1182/Blood.V96.5.1625.H8001625A_1625_1632 |
0.376 |
|
| 1998 |
D'Andrea A, Pellman D. Deubiquitinating enzymes: a new class of biological regulators. Critical Reviews in Biochemistry and Molecular Biology. 33: 337-52. PMID 9827704 DOI: 10.1080/10409239891204251 |
0.307 |
|
| 1998 |
Pulsipher M, Kupfer GM, Naf D, Suliman A, Lee JS, Jakobs P, Grompe M, Joenje H, Sieff C, Guinan E, Mulligan R, D'Andrea AD. Subtyping analysis of Fanconi anemia by immunoblotting and retroviral gene transfer Molecular Medicine. 4: 468-479. PMID 9713825 DOI: 10.1007/Bf03401752 |
0.325 |
|
| 1997 |
Kupfer GM, Näf D, Suliman A, Pulsipher M, D'Andrea AD. The Fanconi anaemia proteins, FAA and FAC, interact to form a nuclear complex. Nature Genetics. 17: 487-90. PMID 9398857 DOI: 10.1038/Ng1297-487 |
0.438 |
|
| 1997 |
Okuda K, D'Andrea A, Etten RA, Griffin JD. A chimeric receptor/oncogene that can be regulated by a ligand in vitro and in vivo. Journal of Clinical Investigation. 100: 1708-1715. PMID 9312168 DOI: 10.1172/Jci119695 |
0.322 |
|
| 1997 |
Jaster R, Zhu Y, Pless M, Bhattacharya S, Mathey-Prevot B, D'Andrea AD. JAK2 is required for induction of the murine DUB-1 gene. Molecular and Cellular Biology. 17: 3364-72. PMID 9154835 DOI: 10.1128/Mcb.17.6.3364 |
0.306 |
|
| 1997 |
Barber DL, Mason JM, Fukazawa T, Reedquist KA, Druker BJ, Band H, D'Andrea AD. Erythropoietin and interleukin-3 activate tyrosine phosphorylation of CBL and association with CRK adaptor proteins. Blood. 89: 3166-74. PMID 9129019 DOI: 10.1182/Blood.V89.9.3166 |
0.338 |
|
| 1997 |
Luo H, Rose P, Barber D, Hanratty WP, Lee S, Roberts TM, D'Andrea AD, Dearolf CR. Mutation in the Jak kinase JH2 domain hyperactivates Drosophila and mammalian Jak-Stat pathways. Molecular and Cellular Biology. 17: 1562-71. PMID 9032284 DOI: 10.1128/Mcb.17.3.1562 |
0.321 |
|
| 1997 |
Zhu Y, Lambert K, Corless C, Copeland NG, Gilbert DJ, Jenkins NA, D'Andrea AD. DUB-2 is a member of a novel family of cytokine-inducible deubiquitinating enzymes. The Journal of Biological Chemistry. 272: 51-7. PMID 8995226 DOI: 10.1074/Jbc.272.1.51 |
0.334 |
|
| 1997 |
Kupfer GM, Yamashita T, Naf D, Suliman A, Asano S, D'Andrea AD. The Fanconi Anemia Polypeptide, FAC, Binds to the Cyclin-Dependent Kinase, cdc2 Blood. 90: 1047-1054. DOI: 10.1182/Blood.V90.3.1047.1047_1047_1054 |
0.386 |
|
| 1996 |
D'Andrea AD. Fanconi anaemia forges a novel pathway. Nature Genetics. 14: 240-2. PMID 8896546 DOI: 10.1038/Ng1196-240 |
0.302 |
|
| 1996 |
Zhu Y, Pless M, Inhorn R, Mathey-Prevot B, D'Andrea AD. The murine DUB-1 gene is specifically induced by the betac subunit of interleukin-3 receptor. Molecular and Cellular Biology. 16: 4808-17. PMID 8756639 DOI: 10.1128/Mcb.16.9.4808 |
0.321 |
|
| 1996 |
Zhu Y, Carroll M, Papa FR, Hochstrasser M, D'Andrea AD. DUB-1, a deubiquitinating enzyme with growth-suppressing activity Proceedings of the National Academy of Sciences of the United States of America. 93: 3275-3279. PMID 8622927 DOI: 10.1073/Pnas.93.8.3275 |
0.344 |
|
| 1996 |
Kupfer GM, D'Andrea AD. THE FANCONI ANEMIA POLYPEPTIDE, FAC, NORMALIZES p53 INDUCTION IN A TRANSFECTED HEMATOPOIETIC CELL LINE. • 930 Pediatric Research. 39: 157-157. DOI: 10.1203/00006450-199604001-00952 |
0.357 |
|
| 1996 |
Kupfer G, D'Andrea A. The effect of the Fanconi anemia polypeptide, FAC, upon p53 induction and G2 checkpoint regulation Blood. 88: 1019-1025. DOI: 10.1182/Blood.V88.3.1019.Bloodjournal8831019 |
0.363 |
|
| 1996 |
Yamashita T, Wu N, Kupfer G, Corless C, Joenje H, Grompe M, D'Andrea A. Clinical variability of Fanconi anemia (type C) results from expression of an amino terminal truncated Fanconi anemia complementation group C polypeptide with partial activity Blood. 87: 4424-4432. DOI: 10.1182/Blood.V87.10.4424.Bloodjournal87104424 |
0.313 |
|
| 1994 |
Yamashita T, Barber DL, Zhu Y, Wu N, D'Andrea AD. The Fanconi anemia polypeptide FACC is localized to the cytoplasm Proceedings of the National Academy of Sciences of the United States of America. 91: 6712-6716. PMID 7517562 DOI: 10.1073/Pnas.91.14.6712 |
0.342 |
|
| 1993 |
Galson DL, Hensold JO, Bishop TR, Schalling M, D'Andrea AD, Jones C, Auron PE, Housman DE. Mouse beta-globin DNA-binding protein B1 is identical to a proto-oncogene, the transcription factor Spi-1/PU.1, and is restricted in expression to hematopoietic cells and the testis. Molecular and Cellular Biology. 13: 2929-41. PMID 8474451 DOI: 10.1128/Mcb.13.5.2929 |
0.393 |
|
| 1992 |
Migliaccio AR, Migliaccio G, D'Andrea A, Baiocchi M, Crotta S, Nicolis S, Ottolenghi S, Adamson JW. Response to erythropoietin in erythroid subclones of the factor-dependent cell line 32D is determined by translocation of the erythropoietin receptor to the cell surface. Proceedings of the National Academy of Sciences of the United States of America. 88: 11086-90. PMID 1722318 DOI: 10.1073/Pnas.88.24.11086 |
0.308 |
|
| 1992 |
Linnekin D, Evans GA, D'Andrea A, Farrar WL. Association of the erythropoietin receptor with protein tyrosine kinase activity. Proceedings of the National Academy of Sciences of the United States of America. 89: 6237-6241. PMID 1378622 DOI: 10.1073/Pnas.89.14.6237 |
0.301 |
|
| 1992 |
Showers MO, D'Andrea AD. Subunit structure and transmembrane signaling of the erythropoietin receptor International Review of Cytology. 137: 99-120. PMID 1336006 DOI: 10.1016/S0074-7696(08)62601-7 |
0.323 |
|
| 1992 |
Emanuel P, Eaves C, Broudy V, Papayannopoulou T, Moore M, D'Andrea A, Prchal J, Eaves A, Prchal J. Familial and congenital polycythemia in three unrelated families Blood. 79: 3019-3030. DOI: 10.1182/Blood.V79.11.3019.3019 |
0.301 |
|
| 1990 |
Youssoufian H, Zon LI, Orkin SH, D'Andrea AD, Lodish HF. Structure and transcription of the mouse erythropoietin receptor gene. Molecular and Cellular Biology. 10: 3675-82. PMID 2162479 DOI: 10.1128/Mcb.10.7.3675 |
0.325 |
|
| 1989 |
Tsai SF, Martin DI, Zon LI, D'Andrea AD, Wong GG, Orkin SH. Cloning of cDNA for the major DNA-binding protein of the erythroid lineage through expression in mammalian cells. Nature. 339: 446-51. PMID 2725678 DOI: 10.1038/339446A0 |
0.41 |
|
| 1983 |
D'Andrea AD, Tantravahi U, Lalande M, Perle MA, Latt SA. High resolution analysis of the timing of replication of specific DNA sequences during S phase of mammalian cells. Nucleic Acids Research. 11: 4753-74. PMID 6192392 DOI: 10.1093/Nar/11.14.4753 |
0.414 |
|
| 1980 |
Haseltine WA, Lo KM, D'Andrea AD. Preferred sites of strand scission in DNA modified by andi-diol epoxide of benzo[a]pyrene. Science (New York, N.Y.). 209: 929-31. PMID 7403858 DOI: 10.1126/Science.7403858 |
0.387 |
|
| 1980 |
Haseltine WA, Lindan CP, D'Andrea AD, Johnsrud L. The use of DNA fragments of defined sequence for the study of DNA damage and repair. Methods in Enzymology. 65: 235-48. PMID 6246348 DOI: 10.1016/S0076-6879(80)65033-2 |
0.456 |
|
| 1978 |
D'Andrea AD, Haseltine WA. Sequence specific cleavage of DNA by the antitumor antibiotics neocarzinostatin and bleomycin. Proceedings of the National Academy of Sciences of the United States of America. 75: 3608-12. PMID 80799 DOI: 10.1073/Pnas.75.8.3608 |
0.418 |
|
| 1978 |
D'Andrea AD, Haseltine WA. Modification of DNA by aflatoxin B1 creates alkali-labile lesions in DNA at positions of guanine and adenine. Proceedings of the National Academy of Sciences of the United States of America. 75: 4120-4. PMID 30083 DOI: 10.1073/Pnas.75.9.4120 |
0.402 |
|
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