Hauke Werner, Ph.D. - Publications

Neurogenetics Max-Planck-Institute for Experimental Medicine, Göttingen, Germany 

67 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Steyer AM, Ruhwedel T, Nardis C, Werner HB, Nave KA, Möbius W. Pathology of myelinated axons in the PLP-deficient mouse model of spastic paraplegia type 2 revealed by volume imaging using focused ion beam-scanning electron microscopy. Journal of Structural Biology. 107492. PMID 32156581 DOI: 10.1016/j.jsb.2020.107492  1
2020 Wakhloo D, Scharkowski F, Curto Y, Javed Butt U, Bansal V, Steixner-Kumar AA, Wüstefeld L, Rajput A, Arinrad S, Zillmann MR, Seelbach A, Hassouna I, Schneider K, Qadir Ibrahim A, Werner HB, et al. Functional hypoxia drives neuroplasticity and neurogenesis via brain erythropoietin. Nature Communications. 11: 1313. PMID 32152318 DOI: 10.1038/s41467-020-15041-1  1
2020 Siems SB, Jahn O, Eichel MA, Kannaiyan N, Wu LMN, Sherman DL, Kusch K, Hesse D, Jung RB, Fledrich R, Sereda MW, Rossner MJ, Brophy PJ, Werner HB. Proteome profile of peripheral myelin in healthy mice and in a neuropathy model. Elife. 9. PMID 32130108 DOI: 10.7554/eLife.51406  0.84
2019 Werner HB, Nave KA. Enhanced Actin Dynamics: A Therapeutic Strategy for Axonal Regeneration? Neuron. 103: 949-950. PMID 31557454 DOI: 10.1016/j.neuron.2019.09.008  1
2019 Buscham TJ, Eichel MA, Siems SB, Werner HB. Turning to myelin turnover. Neural Regeneration Research. 14: 2063-2066. PMID 31397333 DOI: 10.4103/1673-5374.262569  0.52
2019 Joseph S, Vingill S, Jahn O, Fledrich R, Werner HB, Katona I, Möbius W, Mitkovski M, Huang Y, Weis J, Sereda MW, Schulz JB, Nave KA, Stegmüller J. Myelinating glia-specific deletion of Fbxo7 in mice triggers axonal degeneration in the central nervous system together with peripheral neuropathy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31085610 DOI: 10.1523/JNEUROSCI.3094-18.2019  1
2019 Erwig MS, Hesse D, Jung RB, Uecker M, Kusch K, Tenzer S, Jahn O, Werner HB. Myelin: Methods for Purification and Proteome Analysis. Methods in Molecular Biology (Clifton, N.J.). 1936: 37-63. PMID 30820892 DOI: 10.1007/978-1-4939-9072-6_3  0.52
2019 Erwig MS, Patzig J, Steyer AM, Dibaj P, Heilmann M, Heilmann I, Jung RB, Kusch K, Möbius W, Jahn O, Nave KA, Werner HB. Anillin facilitates septin assembly to prevent pathological outfoldings of central nervous system myelin. Elife. 8. PMID 30672734 DOI: 10.7554/eLife.43888  1
2019 Lüders KA, Nessler S, Kusch K, Patzig J, Jung RB, Möbius W, Nave KA, Werner HB. Maintenance of high proteolipid protein level in adult central nervous system myelin is required to preserve the integrity of myelin and axons. Glia. PMID 30637801 DOI: 10.1002/glia.23549  1
2018 Myllykoski M, Eichel MA, Jung RB, Kelm S, Werner HB, Kursula P. High-affinity heterotetramer formation between the large myelin-associated glycoprotein and the dynein light chain DYNLL1. Journal of Neurochemistry. PMID 30261098 DOI: 10.1111/jnc.14598  0.52
2018 Weil MT, Heibeck S, Töpperwien M, Tom Dieck S, Ruhwedel T, Salditt T, Rodicio MC, Morgan JR, Nave KA, Möbius W, Werner HB. Axonal ensheathment in the nervous system of lamprey: Implications for the evolution of myelinating glia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29941446 DOI: 10.1523/JNEUROSCI.1034-18.2018  1
2017 Janova H, Arinrad S, Balmuth E, Mitjans M, Hertel J, Habes M, Bittner RA, Pan H, Goebbels S, Begemann M, Gerwig UC, Langner S, Werner HB, Kittel-Schneider S, Homuth G, et al. Microglia ablation alleviates myelin-associated catatonic signs in mice. The Journal of Clinical Investigation. PMID 29252214 DOI: 10.1172/JCI97032  1
2017 Wang L, Winnewisser J, Federle C, Jessberger G, Nave KA, Werner HB, Kyewski B, Klein L, Hinterberger M. Epitope-Specific Tolerance Modes Differentially Specify Susceptibility to Proteolipid Protein-Induced Experimental Autoimmune Encephalomyelitis. Frontiers in Immunology. 8: 1511. PMID 29170668 DOI: 10.3389/fimmu.2017.01511  1
2017 Lüders KA, Patzig J, Simons M, Nave KA, Werner HB. Genetic dissection of oligodendroglial and neuronal Plp1 function in a novel mouse model of spastic paraplegia type 2. Glia. PMID 28836307 DOI: 10.1002/glia.23193  1
2017 Kusch K, Uecker M, Liepold T, Möbius W, Hoffmann C, Neumann H, Werner HB, Jahn O. Partial Immunoblotting of 2D-Gels: A Novel Method to Identify Post-Translationally Modified Proteins Exemplified for the Myelin Acetylome. Proteomes. 5. PMID 28248254 DOI: 10.3390/proteomes5010003  0.72
2017 Snaidero N, Velte C, Myllykoski M, Raasakka A, Ignatev A, Werner HB, Erwig MS, Möbius W, Kursula P, Nave KA, Simons M. Antagonistic Functions of MBP and CNP Establish Cytosolic Channels in CNS Myelin. Cell Reports. 18: 314-323. PMID 28076777 DOI: 10.1016/j.celrep.2016.12.053  1
2016 Hu B, Arpag S, Zhang X, Möbius W, Werner H, Sosinsky G, Ellisman M, Zhang Y, Hamilton A, Chernoff J, Li J. Tuning PAK Activity to Rescue Abnormal Myelin Permeability in HNPP. Plos Genetics. 12: e1006290. PMID 27583434 DOI: 10.1371/journal.pgen.1006290  0.72
2016 Patzig J, Erwig MS, Tenzer S, Kusch K, Dibaj P, Möbius W, Goebbels S, Schaeren-Wiemers N, Nave KA, Werner HB. Septin/anillin filaments scaffold central nervous system myelin to accelerate nerve conduction. Elife. 5. PMID 27504968 DOI: 10.7554/eLife.17119  1
2016 Poggi G, Boretius S, Möbius W, Moschny N, Baudewig J, Ruhwedel T, Hassouna I, Wieser GL, Werner HB, Goebbels S, Nave KA, Ehrenreich H. Cortical network dysfunction caused by a subtle defect of myelination. Glia. PMID 27470661 DOI: 10.1002/glia.23039  1
2016 Thakurela S, Garding A, Jung RB, Müller C, Goebbels S, White R, Werner HB, Tiwari VK. The transcriptome of mouse central nervous system myelin. Scientific Reports. 6: 25828. PMID 27173133 DOI: 10.1038/srep25828  1
2016 Möbius W, Nave KA, Werner HB. Electron microscopy of myelin: structure preservation by high-pressure freezing. Brain Research. PMID 26920467 DOI: 10.1016/j.brainres.2016.02.027  1
2015 Patzig J, Kusch K, Fledrich R, Eichel MA, Lüders KA, Möbius W, Sereda MW, Nave KA, Martini R, Werner HB. Proteolipid protein modulates preservation of peripheral axons and premature death when myelin protein zero is lacking. Glia. PMID 26393339 DOI: 10.1002/glia.22922  1
2015 Maus F, Sakry D, Binamé F, Karram K, Rajalingam K, Watts C, Heywood R, Krüger R, Stegmüller J, Werner HB, Nave KA, Krämer-Albers EM, Trotter J. The NG2 Proteoglycan Protects Oligodendrocyte Precursor Cells against Oxidative Stress via Interaction with OMI/HtrA2. Plos One. 10: e0137311. PMID 26340347 DOI: 10.1371/journal.pone.0137311  1
2015 Epplen DB, Prukop T, Nientiedt T, Albrecht P, Arlt FA, Stassart RM, Kassmann CM, Methner A, Nave KA, Werner HB, Sereda MW. Curcumin therapy in a Plp1 transgenic mouse model of Pelizaeus-Merzbacher disease. Annals of Clinical and Translational Neurology. 2: 787-96. PMID 26339673 DOI: 10.1002/acn3.219  1
2015 Dere E, Winkler D, Ritter C, Ronnenberg A, Poggi G, Patzig J, Gernert M, Müller C, Nave KA, Ehrenreich H, Werner HB. Gpm6b deficiency impairs sensorimotor gating and modulates the behavioral response to a 5-HT2A/C receptor agonist. Behavioural Brain Research. 277: 254-63. PMID 24768641 DOI: 10.1016/j.bbr.2014.04.021  1
2015 Heuer M, Lichtenberg G, Pfeiffer S, Schlarb H, Werner H. Plant modeling for observer-based control of the link stabilizing units at the European X-ray Free-Electron Laser Proceedings of the American Control Conference. 2015: 5483-5488. DOI: 10.1109/ACC.2015.7172197  0.4
2014 Nave KA, Werner HB. Myelination of the nervous system: mechanisms and functions. Annual Review of Cell and Developmental Biology. 30: 503-33. PMID 25288117 DOI: 10.1146/annurev-cellbio-100913-013101  1
2014 Muneer Z, Wiesinger C, Voigtländer T, Werner HB, Berger J, Forss-Petter S. Abcd2 is a strong modifier of the metabolic impairments in peritoneal macrophages of ABCD1-deficient mice. Plos One. 9: e108655. PMID 25255441 DOI: 10.1371/journal.pone.0108655  1
2014 Mita S, de Monasterio-Schrader P, Fünfschilling U, Kawasaki T, Mizuno H, Iwasato T, Nave KA, Werner HB, Hirata T. Transcallosal Projections Require Glycoprotein M6-Dependent Neurite Growth and Guidance. Cerebral Cortex (New York, N.Y. : 1991). PMID 24917275 DOI: 10.1093/cercor/bhu129  1
2014 Prukop T, Epplen DB, Nientiedt T, Wichert SP, Fledrich R, Stassart RM, Rossner MJ, Edgar JM, Werner HB, Nave KA, Sereda MW. Progesterone antagonist therapy in a Pelizaeus-Merzbacher mouse model. American Journal of Human Genetics. 94: 533-46. PMID 24680886 DOI: 10.1016/j.ajhg.2014.03.001  1
2014 Mostowy S, Bi E, Füchtbauer EM, Goryachev AB, Montagna C, Nagata K, Trimble WS, Werner HB, Yao X, Zieger B, Spiliotis ET. Highlight: the 5th International Workshop on Septin Biology. Biological Chemistry. 395: 119-21. PMID 24334412 DOI: 10.1515/hsz-2013-0291  1
2014 Patzig J, Dworschak MS, Martens AK, Werner HB. Septins in the glial cells of the nervous system. Biological Chemistry. 395: 143-9. PMID 24047595 DOI: 10.1515/hsz-2013-0240  1
2014 Heuer M, Lichtenberg G, Pfeiffer S, Schlarb H, Schmidt C, Werner H. Modeling of the master laser oscillator phase noise for the European XFEL using fractional order systems Ifac Proceedings Volumes (Ifac-Papersonline). 19: 9235-9240.  0.4
2013 Werner HB. Do we have to reconsider the evolutionary emergence of myelin? Frontiers in Cellular Neuroscience. 7: 217. PMID 24298238 DOI: 10.3389/fncel.2013.00217  1
2013 Nawaz S, Schweitzer J, Jahn O, Werner HB. Molecular evolution of myelin basic protein, an abundant structural myelin component. Glia. 61: 1364-77. PMID 24040667 DOI: 10.1002/glia.22520  1
2013 de Monasterio-Schrader P, Patzig J, Möbius W, Barrette B, Wagner TL, Kusch K, Edgar JM, Brophy PJ, Werner HB. Uncoupling of neuroinflammation from axonal degeneration in mice lacking the myelin protein tetraspanin-2. Glia. 61: 1832-47. PMID 24038504 DOI: 10.1002/glia.22561  1
2013 El-Kordi A, Kästner A, Grube S, Klugmann M, Begemann M, Sperling S, Hammerschmidt K, Hammer C, Stepniak B, Patzig J, de Monasterio-Schrader P, Strenzke N, Flügge G, Werner HB, Pawlak R, et al. A single gene defect causing claustrophobia. Translational Psychiatry. 3: e254. PMID 23632458 DOI: 10.1038/tp.2013.28  1
2013 Werner HB, Krämer-Albers EM, Strenzke N, Saher G, Tenzer S, Ohno-Iwashita Y, De Monasterio-Schrader P, Möbius W, Moser T, Griffiths IR, Nave KA. A critical role for the cholesterol-associated proteolipids PLP and M6B in myelination of the central nervous system. Glia. 61: 567-86. PMID 23322581 DOI: 10.1002/glia.22456  1
2013 Jahn O, Tenzer S, Werner HB. Molecular neurobiology: Proteome analysis of myelin, the insulating layer of the nerve | Proteomanalyse des Myelins, der Isolierschicht der Nerven: Molekulare Neurobiologie Biospektrum. 19: 263-265. DOI: 10.1007/s12268-013-0305-1  1
2013 Jahn O, Tenzer S, Bartsch N, Patzig J, Werner HB. Myelin proteome analysis: Methods and implications for the myelin cytoskeleton Neuromethods. 79: 335-353. DOI: 10.1007/978-1-62703-266-7-15  1
2012 Gazzerro E, Baldassari S, Giacomini C, Musante V, Fruscione F, La Padula V, Biancheri R, Scarfì S, Prada V, Sotgia F, Duncan ID, Zara F, Werner HB, Lisanti MP, Nobbio L, et al. Hyccin, the molecule mutated in the leukodystrophy hypomyelination and congenital cataract (HCC), is a neuronal protein. Plos One. 7: e32180. PMID 22461884 DOI: 10.1371/journal.pone.0032180  1
2012 de Monasterio-Schrader P, Jahn O, Tenzer S, Wichert SP, Patzig J, Werner HB. Systematic approaches to central nervous system myelin. Cellular and Molecular Life Sciences : Cmls. 69: 2879-94. PMID 22441408 DOI: 10.1007/s00018-012-0958-9  1
2011 Patzig J, Jahn O, Tenzer S, Wichert SP, de Monasterio-Schrader P, Rosfa S, Kuharev J, Yan K, Bormuth I, Bremer J, Aguzzi A, Orfaniotou F, Hesse D, Schwab MH, Möbius W, ... ... Werner HB, et al. Quantitative and integrative proteome analysis of peripheral nerve myelin identifies novel myelin proteins and candidate neuropathy loci. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 16369-86. PMID 22072688 DOI: 10.1523/JNEUROSCI.4016-11.2011  1
2011 Brendel C, Belakhov V, Werner H, Wegener E, Gärtner J, Nudelman I, Baasov T, Huppke P. Readthrough of nonsense mutations in Rett syndrome: evaluation of novel aminoglycosides and generation of a new mouse model. Journal of Molecular Medicine (Berlin, Germany). 89: 389-98. PMID 21120444 DOI: 10.1007/s00109-010-0704-4  1
2010 Werner HB, Jahn O. Myelin matters: proteomic insights into white matter disorders. Expert Review of Proteomics. 7: 159-64. PMID 20377380 DOI: 10.1586/epr.09.105  1
2009 Edgar JM, McLaughlin M, Werner HB, McCulloch MC, Barrie JA, Brown A, Faichney AB, Snaidero N, Nave KA, Griffiths IR. Early ultrastructural defects of axons and axon-glia junctions in mice lacking expression of Cnp1. Glia. 57: 1815-24. PMID 19459211 DOI: 10.1002/glia.20893  1
2009 Jahn O, Tenzer S, Werner HB. Myelin proteomics: molecular anatomy of an insulating sheath. Molecular Neurobiology. 40: 55-72. PMID 19452287 DOI: 10.1007/s12035-009-8071-2  1
2009 Nawaz S, Kippert A, Saab AS, Werner HB, Lang T, Nave KA, Simons M. Phosphatidylinositol 4,5-bisphosphate-dependent interaction of myelin basic protein with the plasma membrane in oligodendroglial cells and its rapid perturbation by elevated calcium. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 4794-807. PMID 19369548 DOI: 10.1523/JNEUROSCI.3955-08.2009  1
2009 Schardt A, Brinkmann BG, Mitkovski M, Sereda MW, Werner HB, Nave KA. The SNARE protein SNAP-29 interacts with the GTPase Rab3A: Implications for membrane trafficking in myelinating glia. Journal of Neuroscience Research. 87: 3465-79. PMID 19170188 DOI: 10.1002/jnr.22005  1
2009 Corbeil D, Joester A, Fargeas CA, Jászai J, Garwood J, Hellwig A, Werner HB, Huttner WB. Expression of distinct splice variants of the stem cell marker prominin-1 (CD133) in glial cells. Glia. 57: 860-74. PMID 19053060 DOI: 10.1002/glia.20812  1
2009 Buser AM, Erne B, Werner HB, Nave KA, Schaeren-Wiemers N. The septin cytoskeleton in myelinating glia. Molecular and Cellular Neurosciences. 40: 156-66. PMID 19026747 DOI: 10.1016/j.mcn.2008.10.002  1
2008 Möbius W, Patzig J, Nave KA, Werner HB. Phylogeny of proteolipid proteins: divergence, constraints, and the evolution of novel functions in myelination and neuroprotection. Neuron Glia Biology. 4: 111-27. PMID 19497142 DOI: 10.1017/S1740925X0900009X  1
2008 Cooper B, Werner HB, Flügge G. Glycoprotein M6a is present in glutamatergic axons in adult rat forebrain and cerebellum. Brain Research. 1197: 1-12. PMID 18241840 DOI: 10.1016/j.brainres.2007.11.066  1
2008 Chatterjee N, Stegmüller J, Schätzle P, Karram K, Koroll M, Werner HB, Nave KA, Trotter J. Interaction of syntenin-1 and the NG2 proteoglycan in migratory oligodendrocyte precursor cells. The Journal of Biological Chemistry. 283: 8310-7. PMID 18218632 DOI: 10.1074/jbc.M706074200  1
2007 Kassmann CM, Lappe-Siefke C, Baes M, Brügger B, Mildner A, Werner HB, Natt O, Michaelis T, Prinz M, Frahm J, Nave KA. Axonal loss and neuroinflammation caused by peroxisome-deficient oligodendrocytes. Nature Genetics. 39: 969-76. PMID 17643102 DOI: 10.1038/ng2070  1
2007 Werner HB, Kuhlmann K, Shen S, Uecker M, Schardt A, Dimova K, Orfaniotou F, Dhaunchak A, Brinkmann BG, Möbius W, Guarente L, Casaccia-Bonnefil P, Jahn O, Nave KA. Proteolipid protein is required for transport of sirtuin 2 into CNS myelin. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 7717-30. PMID 17634366 DOI: 10.1523/JNEUROSCI.1254-07.2007  1
2006 Schweitzer J, Becker T, Schachner M, Nave KA, Werner H. Evolution of myelin proteolipid proteins: gene duplication in teleosts and expression pattern divergence. Molecular and Cellular Neurosciences. 31: 161-77. PMID 16289898 DOI: 10.1016/j.mcn.2005.10.007  1
2005 Itoh T, Erdmann KS, Roux A, Habermann B, Werner H, De Camilli P. Dynamin and the actin cytoskeleton cooperatively regulate plasma membrane invagination by BAR and F-BAR proteins. Developmental Cell. 9: 791-804. PMID 16326391 DOI: 10.1016/j.devcel.2005.11.005  1
2005 Nave KA, Werner H. Mutations of Myelination-Associated Genes that Affect Axonal Integrity Multiple Sclerosis as a Neuronal Disease. 305-315. DOI: 10.1016/B978-012738761-1/50022-5  1
2004 Morgan JR, Di Paolo G, Werner H, Shchedrina VA, Pypaert M, Pieribone VA, De Camilli P. A role for talin in presynaptic function. The Journal of Cell Biology. 167: 43-50. PMID 15479735 DOI: 10.1083/jcb.200406020  1
2003 Rodemer C, Thai TP, Brugger B, Kaercher T, Werner H, Nave KA, Wieland F, Gorgas K, Just WW. Inactivation of ether lipid biosynthesis causes male infertility, defects in eye development and optic nerve hypoplasia in mice. Human Molecular Genetics. 12: 1881-95. PMID 12874108 DOI: 10.1093/hmg/ddg191  1
2003 Stegmüller J, Werner H, Nave KA, Trotter J. The proteoglycan NG2 is complexed with alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors by the PDZ glutamate receptor interaction protein (GRIP) in glial progenitor cells. Implications for glial-neuronal signaling. The Journal of Biological Chemistry. 278: 3590-8. PMID 12458226 DOI: 10.1074/jbc.M210010200  1
2001 Werner H, Dimou L, Klugmann M, Pfeiffer S, Nave KA. Multiple splice isoforms of proteolipid M6B in neurons and oligodendrocytes. Molecular and Cellular Neurosciences. 18: 593-605. PMID 11749036 DOI: 10.1006/mcne.2001.1044  1
1999 Dimou L, Klugmann M, Werner H, Jung M, Griffiths IR, Nave KA. Dysmyelination in mice and the proteolipid protein gene family. Advances in Experimental Medicine and Biology. 468: 261-71. PMID 10635035  1
1998 Werner H, Jung M, Klugmann M, Sereda M, Griffiths IR, Nave KA. Mouse models of myelin diseases. Brain Pathology (Zurich, Switzerland). 8: 771-93. PMID 9804383  1
1998 Vouyiouklis DA, Werner H, Griffiths IR, Stewart GJ, Armin-Nave K, Thomson CE. Molecular cloning and transfection studies of M6b-2, a novel splice variant of a member of the PLP-DM20/M6 gene family Journal of Neuroscience Research. 52: 633-640. PMID 9669312 DOI: 10.1002/(SICI)1097-4547(19980615)52:6<633::AID-JNR2>3.0.CO;2-9  1
1997 Forss-Petter S, Werner H, Berger J, Lassmann H, Molzer B, Schwab MH, Bernheimer H, Zimmermann F, Nave KA. Targeted inactivation of the X-linked adrenoleukodystrophy gene in mice. Journal of Neuroscience Research. 50: 829-43. PMID 9418970 DOI: 10.1002/(SICI)1097-4547(19971201)50:5<829::AID-JNR19>3.0.CO;2-W  1
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