| Year |
Citation |
Score |
| 2017 |
Roy S, Axup JY, Forsyth JS, Goswami RK, Hutchins BM, Bajuri KM, Kazane SA, Smider VV, Felding BH, Sinha SC. SMI-Ribosome inactivating protein conjugates selectively inhibit tumor cell growth. Chemical Communications (Cambridge, England). PMID 28357420 DOI: 10.1039/C7Cc00745K |
0.69 |
|
| 2016 |
Walseng E, Nelson CG, Qi J, Nanna AR, Roush WR, Goswami RK, Sinha SC, Burke TR, Rader C. Chemically programmed bispecific antibodies in diabody format. The Journal of Biological Chemistry. PMID 27445334 DOI: 10.1074/Jbc.M116.745588 |
0.728 |
|
| 2015 |
Liu Y, Goswami RK, Liu C, Sinha SC. Chemically Programmed Bispecific Antibody Targeting Legumain Protease and αvβ3 Integrin Mediates Strong Antitumor Effects. Molecular Pharmaceutics. 12: 2544-50. PMID 26024761 DOI: 10.1021/Acs.Molpharmaceut.5B00257 |
0.729 |
|
| 2013 |
Goswami RK, Liu Y, Liu C, Lerner RA, Sinha SC. Synthesis and evaluation of the aldolase antibody-derived chemical-antibodies targeting α5β1 integrin. Molecular Pharmaceutics. 10: 538-43. PMID 23102054 DOI: 10.1021/Mp3004463 |
0.725 |
|
| 2012 |
Axup JY, Bajjuri KM, Ritland M, Hutchins BM, Kim CH, Kazane SA, Halder R, Forsyth JS, Santidrian AF, Stafin K, Lu Y, Tran H, Seller AJ, Biroc SL, Szydlik A, ... ... Sinha SC, et al. Synthesis of site-specific antibody-drug conjugates using unnatural amino acids. Proceedings of the National Academy of Sciences of the United States of America. 109: 16101-6. PMID 22988081 DOI: 10.1073/Pnas.1211023109 |
0.437 |
|
| 2012 |
Liu Y, Bajjuri KM, Liu C, Sinha SC. Targeting cell surface alpha(v)beta(3) integrin increases therapeutic efficacies of a legumain protease-activated auristatin prodrug. Molecular Pharmaceutics. 9: 168-75. PMID 22044266 DOI: 10.1021/Mp200434N |
0.359 |
|
| 2011 |
Liu Y, Jiang P, Capkova K, Xue D, Ye L, Sinha SC, Mackman N, Janda KD, Liu C. Tissue factor-activated coagulation cascade in the tumor microenvironment is critical for tumor progression and an effective target for therapy. Cancer Research. 71: 6492-502. PMID 21880589 DOI: 10.1158/0008-5472.Can-11-1145 |
0.353 |
|
| 2011 |
Goswami RK, Bajjuri KM, Forsyth JS, Das S, Hassenpflug W, Huang ZZ, Lerner RA, Felding-Habermann B, Sinha SC. Chemically programmed antibodies targeting multiple alpha(v) integrins and their effects on tumor-related functions in vitro. Bioconjugate Chemistry. 22: 1535-44. PMID 21774545 DOI: 10.1021/Bc2000879 |
0.715 |
|
| 2011 |
Bajjuri KM, Liu Y, Liu C, Sinha SC. The legumain protease-activated auristatin prodrugs suppress tumor growth and metastasis without toxicity. Chemmedchem. 6: 54-9. PMID 21154805 DOI: 10.1002/Cmdc.201000478 |
0.438 |
|
| 2010 |
Mishra JK, Wipf P, Sinha SC. Studies toward a library of tetrahydrofurans: click and MCR products of mono- and bis-tetrahydrofurans. Journal of Combinatorial Chemistry. 12: 609-12. PMID 20614864 DOI: 10.1021/Cc1000709 |
0.338 |
|
| 2010 |
Bajjurri KM, Goswami RK, Erigala VR, Liu Y, Liu C, Sinha SC. Abstract 3715: Potent cytotoxins and their prodrugs Cancer Research. 70: 3715-3715. DOI: 10.1158/1538-7445.Am10-3715 |
0.721 |
|
| 2009 |
Li LS, Sinha SC. Studies toward the duocarmycin prodrugs for the antibody prodrug therapy approach. Tetrahedron Letters. 50: 2933-2935. PMID 20160897 DOI: 10.1016/J.Tetlet.2009.03.205 |
0.427 |
|
| 2009 |
Gavrilyuk JI, Wuellner U, Salahuddin S, Goswami RK, Sinha SC, Barbas CF. An efficient chemical approach to bispecific antibodies and antibodies of high valency Bioorganic and Medicinal Chemistry Letters. 19: 3716-3720. PMID 19497743 DOI: 10.1016/J.Bmcl.2009.05.047 |
0.716 |
|
| 2009 |
Goswami RK, Huang ZZ, Forsyth JS, Felding-Habermann B, Sinha SC. Multiple catalytic aldolase antibodies suitable for chemical programming. Bioorganic & Medicinal Chemistry Letters. 19: 3821-4. PMID 19428247 DOI: 10.1016/J.Bmcl.2009.04.041 |
0.736 |
|
| 2009 |
Popkov M, Gonzalez B, Sinha SC, Barbas CF. Instant immunity through chemically programmable vaccination and covalent self-assembly. Proceedings of the National Academy of Sciences of the United States of America. 106: 4378-83. PMID 19255430 DOI: 10.1073/Pnas.0900147106 |
0.335 |
|
| 2009 |
Chen Z, Sinha SC. Synthesis of 10 stereochemically distinct bis-tetrahydrofuran intermediates for creating a library of 64 asimicin stereoisomers Tetrahedron Letters. 50: 6398-6401. DOI: 10.1016/J.Tetlet.2009.08.082 |
0.337 |
|
| 2008 |
Sinha SC, Chen Z, Huang ZZ, Nakamaru-Ogiso E, Pietraszkiewicz H, Edelstein M, Valeriote F. Alteration of the bis-tetrahydrofuran core stereochemistries in asimicin can affect the cytotoxicity. Journal of Medicinal Chemistry. 51: 7045-8. PMID 18975929 DOI: 10.1021/Jm801028C |
0.31 |
|
| 2008 |
Chen Z, Sinha SC. Total synthesis of 27-hydroxy-bullatacin and its C-15 epimer, and studies on their inhibitory effect on bovine heart mitochondrial complex I functions Tetrahedron. 64: 1603-1611. DOI: 10.1016/J.Tet.2007.11.089 |
0.347 |
|
| 2007 |
Das S, Abraham S, Sinha SC. Studies toward the total synthesis of sorangiolides and their analogues. A convergent stereoselective synthesis of the macrocyclic lactone precursors. Organic Letters. 9: 2273-6. PMID 17503834 DOI: 10.1021/Ol070517G |
0.355 |
|
| 2007 |
Sinha SC, Das S, Li LS, Lerner RA, Barbas CF. Preparation of integrin alpha(v)beta3-targeting Ab 38C2 constructs. Nature Protocols. 2: 449-56. PMID 17406606 DOI: 10.1038/Nprot.2007.3 |
0.391 |
|
| 2007 |
Abraham S, Guo F, Li LS, Rader C, Liu C, Barbas CF, Lerner RA, Sinha SC. Synthesis of the next-generation therapeutic antibodies that combine cell targeting and antibody-catalyzed prodrug activation. Proceedings of the National Academy of Sciences of the United States of America. 104: 5584-9. PMID 17372220 DOI: 10.1073/Pnas.0700223104 |
0.439 |
|
| 2006 |
Guo F, Das S, Mueller BM, Barbas CF, Lerner RA, Sinha SC. Breaking the one antibody-one target axiom. Proceedings of the National Academy of Sciences of the United States of America. 103: 11009-14. PMID 16822849 DOI: 10.1073/Pnas.0603822103 |
0.451 |
|
| 2006 |
Popkov M, Rader C, Gonzalez B, Sinha SC, Barbas CF. Small molecule drug activity in melanoma models may be dramatically enhanced with an antibody effector. International Journal of Cancer. Journal International Du Cancer. 119: 1194-207. PMID 16570283 DOI: 10.1002/Ijc.21924 |
0.481 |
|
| 2005 |
Das S, Li LS, Abraham S, Chen Z, Sinha SC. A bidirectional approach to the synthesis of a complete library of adjacent-bis-THF annonaceous acetogenins. The Journal of Organic Chemistry. 70: 5922-31. PMID 16018687 DOI: 10.1021/Jo050697C |
0.339 |
|
| 2005 |
Saphier S, Hu Y, Sinha SC, Houk KN, Keinan E. Origin of selectivity in the antibody 20F10-catalyzed Yang cyclization. Journal of the American Chemical Society. 127: 132-45. PMID 15631463 DOI: 10.1021/Ja045419U |
0.385 |
|
| 2004 |
Li LS, Rader C, Matsushita M, Das S, Barbas CF, Lerner RA, Sinha SC. Chemical adaptor immunotherapy: design, synthesis, and evaluation of novel integrin-targeting devices. Journal of Medicinal Chemistry. 47: 5630-40. PMID 15509162 DOI: 10.1021/Jm049666K |
0.431 |
|
| 2004 |
Sinha SC, Li LS, Watanabe S, Kaltgrad E, Tanaka F, Rader C, Lerner RA, Barbas CF. Aldolase antibody activation of prodrugs of potent aldehyde-containing cytotoxics for selective chemotherapy. Chemistry (Weinheim An Der Bergstrasse, Germany). 10: 5467-72. PMID 15378729 DOI: 10.1002/Chem.200400419 |
0.378 |
|
| 2004 |
Han H, Sinha MK, D'Souza LJ, Keinan E, Sinha SC. Total synthesis of 34-hydroxyasimicin and its photoactive derivative for affinity labeling of the mitochondrial complex I. Chemistry (Weinheim An Der Bergstrasse, Germany). 10: 2149-58. PMID 15112203 DOI: 10.1002/Chem.200305557 |
0.37 |
|
| 2004 |
Sinha SC, Li LS, Miller GP, Dutta S, Rader C, Lerner RA. Prodrugs of dynemicin analogs for selective chemotherapy mediated by an aldolase catalytic Ab. Proceedings of the National Academy of Sciences of the United States of America. 101: 3095-9. PMID 14981258 DOI: 10.1073/Pnas.0307319101 |
0.409 |
|
| 2004 |
Li LS, Das S, Sinha SC. Efficient one-step aldol-type reaction of ketones with acetals and ketals mediated by dibutylboron triflate/diisopropylethyl amine. Organic Letters. 6: 127-30. PMID 14703367 DOI: 10.1021/Ol030108U |
0.336 |
|
| 2004 |
Das S, Li LS, Sinha SC. Stereoselective aldol-type cyclization reaction mediated by dibutylboron triflate/diisopropylethylamine. Organic Letters. 6: 123-6. PMID 14703366 DOI: 10.1021/Ol036229B |
0.323 |
|
| 2003 |
Rader C, Turner JM, Heine A, Shabat D, Sinha SC, Wilson IA, Lerner RA, Barbas CF. A humanized aldolase antibody for selective chemotherapy and adaptor immunotherapy. Journal of Molecular Biology. 332: 889-99. PMID 12972259 DOI: 10.1016/S0022-2836(03)00992-6 |
0.447 |
|
| 2003 |
Rader C, Sinha SC, Popkov M, Lerner RA, Barbas CF. Chemically programmed monoclonal antibodies for cancer therapy: adaptor immunotherapy based on a covalent antibody catalyst. Proceedings of the National Academy of Sciences of the United States of America. 100: 5396-400. PMID 12702756 DOI: 10.1073/Pnas.0931308100 |
0.445 |
|
| 2003 |
Saphier S, Sinha SC, Keinan E. Antibody-catalyzed enantioselective Norrish type II cyclization. Angewandte Chemie (International Ed. in English). 42: 1378-81. PMID 12671973 DOI: 10.1002/Anie.200390353 |
0.337 |
|
| 2002 |
Sun J, Sinha SC. Stereoselective total synthesis of epothilones by the metathesis approach involving C9-C10 bond formation. Angewandte Chemie (International Ed. in English). 41: 1381-3. PMID 19750771 DOI: 10.1002/1521-3773(20020415)41:8<1381::Aid-Anie1381>3.0.Co;2-O |
0.301 |
|
| 2002 |
Keinan E, Sinha SC. Oxidative polycyclizations with rhenium(VII) oxides Pure and Applied Chemistry. 74: 93-105. DOI: 10.1351/Pac200274010093 |
0.325 |
|
| 2001 |
Sinha SC, Sun J, Wartmann M, Lerner RA. Synthesis of epothilone analogues by antibody-catalyzed resolution of thiazole aldol synthons on a multigram scale. Biological consequences of C-13 alkylation of epothilones. Chembiochem : a European Journal of Chemical Biology. 2: 656-65. PMID 11828502 DOI: 10.1002/1439-7633(20010903)2:9<656::Aid-Cbic656>3.0.Co;2-3 |
0.405 |
|
| 2001 |
Sinha SC, Sun J, Miller GP, Wartmann M, Lerner RA. Catalytic antibody route to the naturally occurring epothilones: total synthesis of epothilones A-F. Chemistry (Weinheim An Der Bergstrasse, Germany). 7: 1691-702. PMID 11349910 DOI: 10.1002/1521-3765(20010417)7:8<1691::Aid-Chem16910>3.0.Co;2-9 |
0.429 |
|
| 2001 |
D'Souza LJ, Sinha SC, Lu S, Keinan E, Sinha SC. Oxidative polycyclization with rhenium(VII) oxides: application of the stereoselectivity rules in the total synthesis of rollidecins C and D Tetrahedron. 57: 5255-5262. DOI: 10.1016/S0040-4020(01)00381-7 |
0.334 |
|
| 2000 |
Sinha SC, Dutta S, Sun J. Regioselective synthesis of fluoroaldols. Studies toward fluoroepothilones syntheses via antibody catalysis Tetrahedron Letters. 41: 8243-8246. DOI: 10.1016/S0040-4039(00)01469-6 |
0.387 |
|
| 1999 |
Sinha SC, Sun J, Miller G, Barbas CF, Lerner RA. Sets of aldolase antibodies with antipodal reactivities. Formal synthesis of epothilone E by large-scale antibody-catalyzed resolution of thiazole aldol. Organic Letters. 1: 1623-6. PMID 10836025 DOI: 10.1021/Ol990261H |
0.366 |
|
| 1999 |
Sinha A, Sinha SC, Sinha SC, Keinan E. Total Synthesis of Trilobin Journal of Organic Chemistry. 64: 2381-2386. DOI: 10.1021/Jo982110I |
0.345 |
|
| 1998 |
Zhong G, Shabat D, List B, Anderson J, Sinha SC, Lerner RA, Barbas Iii CF. Catalytic Enantioselective Retro-Aldol Reactions: Kinetic Resolution of β-Hydroxyketones with Aldolase Antibodies. Angewandte Chemie (International Ed. in English). 37: 2481-2484. PMID 29711357 DOI: 10.1002/(Sici)1521-3773(19981002)37:18<2481::Aid-Anie2481>3.0.Co;2-T |
0.401 |
|
| 1998 |
Yazbak A, Sinha SC, Keinan E. Total Synthesis of Uvaricin. The Journal of Organic Chemistry. 63: 5863-5868. PMID 11672188 DOI: 10.1021/Jo980453A |
0.321 |
|
| 1998 |
Sinha SC, Barbas CF, Lerner RA. The antibody catalysis route to the total synthesis of epothilones. Proceedings of the National Academy of Sciences of the United States of America. 95: 14603-8. PMID 9843936 DOI: 10.1073/Pnas.95.25.14603 |
0.432 |
|
| 1998 |
Neogi P, Doundoulakis T, Yazbak A, Sinha SC, Keinan E. Total synthesis of mucocin Journal of the American Chemical Society. 120: 11279-11284. DOI: 10.1021/Ja981302S |
0.349 |
|
| 1997 |
Sinha SC, Keinan E. Total Synthesis of (+)-Aspicilin. The Naked Carbon Skeleton Strategy vs the Bioorganic Approach. The Journal of Organic Chemistry. 62: 377-386. PMID 11671413 DOI: 10.1021/Jo9614811 |
0.352 |
|
| 1997 |
Keinan E, Sinha A, Yazbak A, Sinha SC, Sinha SC. Towards chemical libraries of annonaceous acetogenins Pure and Applied Chemistry. 69: 423-430. DOI: 10.1351/Pac199769030423 |
0.367 |
|
| 1997 |
Sinha SC, Sinha A, Sinha aSC, Keinan E. Tandem Oxidative Cyclization With Rhenium Oxide. Total Synthesis Of 17,18-Bisepi-Goniocin Journal of the American Chemical Society. 119: 12014-12015. DOI: 10.1021/Ja964273Z |
0.328 |
|
| 1996 |
Sinha SC, Sinha A, Yazbak A, Keinan E. Toward Chemical Libraries of Annonaceous Acetogenins. Total Synthesis of Trilobacin. The Journal of Organic Chemistry. 61: 7640-7641. PMID 11667706 DOI: 10.1021/Jo961286M |
0.334 |
|
| 1996 |
Keinan E, Sinha SC, Shabat D, Itzhaky H, Reymond JL. Asymmetric organic synthesis with catalytic antibodies. Acta Chemica Scandinavica (Copenhagen, Denmark : 1989). 50: 679-87. PMID 8756356 DOI: 10.3891/ACTA.CHEM.SCAND.50-0679 |
0.333 |
|
| 1996 |
Ghosh P, Shabat D, Kumar S, Sinha SC, Grynszpan F, Li J, Noodleman L, Keinan E. Using antibodies to perturb the coordination sphere of a transition metal complex. Nature. 382: 339-41. PMID 8684461 DOI: 10.1038/382339A0 |
0.314 |
|
| 1996 |
Sinha SC, Keinan E. α‐Multistriatin: The First Total Synthesis of a Natural Product via Antibody Catalysis Israel Journal of Chemistry. 36: 185-193. DOI: 10.1002/Ijch.199600025 |
0.441 |
|
| 1996 |
Shabat D, Sinha SC, Reymond JL, Keinan E. Catalytic antibodies as probes of evolution: Modeling of a primordial glycosidase Angewandte Chemie - International Edition in English. 35: 2628-2630. DOI: 10.1002/Anie.199626281 |
0.363 |
|
| 1995 |
Sinha SC, Keinan E. Catalytic Antibodies In Organic Synthesis. Asymmetric Synthesis Of (-)-Alpha -Multistriatin Journal of the American Chemical Society. 117: 3653-3654. DOI: 10.1021/Ja00117A051 |
0.358 |
|
| 1995 |
Kido F, Yamaji K, Sinha SC, Abiko T, Kato M. Carbocyclic construction by the [2,3]sigmatropic rearrangement of cyclic sulfonium ylides. a new entry for the stereoselective synthesis of substituted cyclohexanones Tetrahedron. 51: 7697-7714. DOI: 10.1016/0040-4020(95)00409-2 |
0.34 |
|
| 1994 |
Kido F, Yamaji K, Sinha SC, Yoshikoshi A, Kato M. Steric control based on alkyl substituents in the [2,3]sigmatropic rearrangement of nine-membered allylsulfonium ylides. A new entry to the stereoselective synthesis of elemane-type sesquiterpenoids Journal of the Chemical Society, Chemical Communications. 789-790. DOI: 10.1039/C39940000789 |
0.305 |
|
| 1994 |
Sinha SC, Keinan E. Short Synthesis of (+)-Aspicilin via Asymmetric Hexahydroxylation of a Triene Journal of Organic Chemistry. 59: 949-951. DOI: 10.1021/Jo00084A006 |
0.304 |
|
| 1993 |
Sinha SC, Keinan E, Reymond J. Antibody-catalyzed reversal of chemoselectivity. Proceedings of the National Academy of Sciences of the United States of America. 90: 11910-11913. PMID 8265647 DOI: 10.1073/Pnas.90.24.11910 |
0.428 |
|
| 1993 |
Sinha SC, Sinha-Bagchi A, Keinan E. A general approach to enantiomerically pure methylcarbinols. Asymmetric synthesis of antibiotic (-)-A26771B and the WCR sex pheromone Journal of Organic Chemistry. 58: 7789-7796. DOI: 10.1021/Jo00079A024 |
0.342 |
|
| 1993 |
Sinha SC, Keinan E, Reymond JL. Antibody-catalyzed enantioselective epoxide hydrolysis Journal of the American Chemical Society. 115: 4893-4894. DOI: 10.1021/Ja00064A061 |
0.404 |
|
| 1993 |
Sinha SC, Keinan E. Total synthesis of naturally occurring acetogenins : solamin and reticulatacin Journal of the American Chemical Society. 115: 4891-4892. DOI: 10.1021/Ja00064A060 |
0.306 |
|
| 1992 |
Keinan E, Sinha SC, Sinha-Bagchi A. Thermostable enzymes in organic synthesis. 7. Total synthesis of the western corn rootworm sex pheromone 8-methyldec-2-yl propanoate using a TBADH-generated C2-bifunctional chiron Journal of Organic Chemistry. 57: 3631-3636. DOI: 10.1021/Jo00039A023 |
0.315 |
|
| 1992 |
Keinan E, Benory E, Sinha SC, Sinha-Bagchi A, Eren D, Eshhar Z, Green BS. Catalytic antibodies. Circular dichroism and UV-vis studies of antibody-metalloporphyrin interactions Inorganic Chemistry. 31: 5433-5438. DOI: 10.1021/Ic00052A019 |
0.346 |
|
| 1992 |
Keinan E, Sinha SC, Sinha-Bagchi A, Zhi-Min W, Xiu-Lian Z, Sharpless KB. Synthesis of all four isomers of disparlure using osmium-catalyzed asymmetric dihydroxylation Tetrahedron Letters. 33: 6411-6414. DOI: 10.1016/S0040-4039(00)79002-2 |
0.313 |
|
| 1991 |
Keinan E, Sinha SC, Sinha-Bagchi A. Thermostable enzymes in organic synthesis, Part 6. Total synthesis of (S)–(–)-zearalenone using a TBADH-generated trifunctional chiron Journal of the Chemical Society-Perkin Transactions 1. 3333-3339. DOI: 10.1039/P19910003333 |
0.315 |
|
| 1991 |
Keinan E, Sinha SC, Singh SP. Thermostable enzymes in organic synthesis, 5. Total synthesis of S-(+)-Z-dodec-3-en-11-olide (ferrulactone II) using a tbadh-generated bifunctional chiron. Tetrahedron. 47: 4631-4638. DOI: 10.1016/S0040-4020(01)86469-3 |
0.308 |
|
| 1990 |
Keinan E, Sinha SC, Sinha-Bagchi A, Benory E, Ghozi MC, Eshhar Z, Green BS. Towards antibody-mediated metallo-porphyrin chemistry Pure and Applied Chemistry. 62: 2013-2019. DOI: 10.1351/Pac199062102013 |
0.4 |
|
| 1990 |
Kido F, Sinha SC, Abiko T, Watanabe M, Yoshikoshi A. Stereoselectivity in the sigmatropic rearrangement of eight- and nine-membered cyclic allylsulfonium ylides. synthesis of vinyl- substituted butyro- and valerolactones Tetrahedron. 46: 4887-4906. DOI: 10.1016/S0040-4020(01)85601-5 |
0.323 |
|
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