Benoit I. Giasson, Ph.D. - Publications

Pharmacology University of Pennsylvania, Philadelphia, PA, United States 
 Neuroscience University of Florida, Gainesville, Gainesville, FL, United States 
Neurodegeneration ,Parkinson’s disease, Neuronal Damage, Protein Aggregation,Kinases, Alpha-synuclein, Tau

211 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Lloyd GM, Long B, Quintin S, Sorrentino ZA, Gorion KM, Bell BM, Carrillo D, Sullivan P, Borchelt D, Giasson BI. Carboxyl truncation of α-synuclein occurs early and is influenced by human APOE genotype in transgenic mouse models of α-synuclein pathogenesis. Acta Neuropathologica Communications. 11: 119. PMID 37482615 DOI: 10.1186/s40478-023-01623-9  0.34
2023 Quintin S, Lloyd GM, Paterno G, Xia Y, Sorrentino Z, Bell BM, Gorion KM, Lee EB, Prokop S, Giasson BI. Cellular processing of α-synuclein fibrils results in distinct physiological C-terminal truncations with a major cleavage site at residue Glu 114. The Journal of Biological Chemistry. 104912. PMID 37307916 DOI: 10.1016/j.jbc.2023.104912  0.755
2023 Xia Y, Bell BM, Kim JD, Giasson BI. Tau mutation S356T in the three repeat isoform leads to microtubule dysfunction and promotes prion-like seeded aggregation. Frontiers in Neuroscience. 17: 1181804. PMID 37304025 DOI: 10.3389/fnins.2023.1181804  0.312
2023 Xia Y, Bell BM, Giasson BI. Tau Lysine Pseudomethylation Regulates Microtubule Binding and Enhances Prion-like Tau Aggregation. International Journal of Molecular Sciences. 24. PMID 37175990 DOI: 10.3390/ijms24098286  0.71
2022 Croft CL, Paterno G, Vause AR, Rowe LA, Ryu DH, Goodwin MS, Moran CA, Cruz PE, Giasson BI, Golde TE. Optical pulse labeling studies reveal exogenous seeding slows α-synuclein clearance. Npj Parkinson's Disease. 8: 173. PMID 36535953 DOI: 10.1038/s41531-022-00434-4  0.303
2022 Paterno G, Bell BM, Gorion KM, Prokop S, Giasson BI. Reassessment of Neuronal Tau Distribution in Adult Human Brain and Implications for Tau Pathobiology. Acta Neuropathologica Communications. 10: 94. PMID 35765058 DOI: 10.1186/s40478-022-01394-9  0.739
2022 Sorrentino ZA, Hass E, Vijayaraghavan N, Gorion KM, Riffe CJ, Dhillon JS, Giasson BI. Corrigendum to "Carboxy-terminal truncation and phosphorylation of α-synuclein elongates survival in a prion-like seeding mouse model of synucleinopathy" [Neurosci. Lett. 732 (2020) 1-11/135017]. Neuroscience Letters. 783: 136719. PMID 35717861 DOI: 10.1016/j.neulet.2022.136719  0.719
2022 Xia Y, Prokop S, Bell BM, Gorion KM, Croft CL, Nasif L, Xu G, Riffe CJ, Manaois AN, Strang KH, Quintin SS, Paterno G, Tansey MG, Borchelt DR, Golde TE, ... Giasson BI, et al. Pathogenic tau recruits wild-type tau into brain inclusions and induces gut degeneration in transgenic SPAM mice. Communications Biology. 5: 446. PMID 35550593 DOI: 10.1038/s42003-022-03373-1  0.831
2022 Moore BD, Levites Y, Xu G, Hampton H, Adamo MF, Croft CL, Futch HS, Moran C, Fromholt S, Janus C, Prokop S, Dickson D, Lewis J, Giasson BI, Golde TE, et al. Soluble brain homogenates from diverse human and mouse sources preferentially seed diffuse Aβ plaque pathology when injected into newborn mouse hosts. Free Neuropathology. 3. PMID 35494163 DOI: 10.17879/freeneuropathology-2022-3766  0.737
2022 Lloyd GM, Sorrentino ZA, Quintin S, Gorion KM, Bell BM, Paterno G, Long B, Prokop S, Giasson BI. Unique seeding profiles and prion-like propagation of synucleinopathies are highly dependent on the host in human α-synuclein transgenic mice. Acta Neuropathologica. PMID 35488930 DOI: 10.1007/s00401-022-02425-4  0.829
2022 Williams T, Ruiz AJ, Ruiz AM, Vo Q, Tsering W, Xu G, McFarland K, Giasson BI, Sullivan P, Borchelt DR, Chakrabarty P. Impact of APOE genotype on prion-type propagation of tauopathy. Acta Neuropathologica Communications. 10: 57. PMID 35440098 DOI: 10.1186/s40478-022-01359-y  0.316
2021 Xia Y, Lloyd GM, Giasson BI. Targeted proteolytic products of τ and α-synuclein in neurodegeneration. Essays in Biochemistry. 65: 905-912. PMID 34846537 DOI: 10.1042/EBC20210028  0.826
2021 Koller EJ, Ibanez KR, Vo Q, McFarland KN, Gonzalez De La Cruz E, Zobel L, Williams T, Xu G, Ryu D, Patel P, Giasson BI, Prokop S, Chakrabarty P. Combinatorial model of amyloid β and tau reveals synergy between amyloid deposits and tangle formation. Neuropathology and Applied Neurobiology. PMID 34825397 DOI: 10.1111/nan.12779  0.725
2021 Lloyd GM, Dhillon JS, Gorion KM, Riffe C, Fromholt SE, Xia Y, Giasson BI, Borchelt DR. Collusion of α-Synuclein and Aβ aggravating co-morbidities in a novel prion-type mouse model. Molecular Neurodegeneration. 16: 63. PMID 34503546 DOI: 10.1186/s13024-021-00486-9  0.838
2021 Hass EW, Sorrentino ZA, Xia Y, Lloyd GM, Trojanowski JQ, Prokop S, Giasson BI. Disease-, region- and cell type specific diversity of α-synuclein carboxy terminal truncations in synucleinopathies. Acta Neuropathologica Communications. 9: 146. PMID 34454615 DOI: 10.1186/s40478-021-01242-2  0.832
2021 Xia Y, Bell BM, Giasson BI. Tau K321/K353 pseudoacetylation within KXGS motifs regulates tau-microtubule interactions and inhibits aggregation. Scientific Reports. 11: 17069. PMID 34426645 DOI: 10.1038/s41598-021-96627-7  0.743
2021 Dagra A, Miller DR, Lin M, Gopinath A, Shaerzadeh F, Harris S, Sorrentino ZA, Støier JF, Velasco S, Azar J, Alonge AR, Lebowitz JJ, Ulm B, Bu M, Hansen CA, ... ... Giasson BI, et al. α-Synuclein-induced dysregulation of neuronal activity contributes to murine dopamine neuron vulnerability. Npj Parkinson's Disease. 7: 76. PMID 34408150 DOI: 10.1038/s41531-021-00210-w  0.724
2021 Ferreira N, Richner M, van der Laan A, Bergholdt Jul Christiansen I, Vægter CB, Nyengaard JR, Halliday GM, Weiss J, Giasson BI, Mackenzie IR, Jensen PH, Jan A. Prodromal neuroinvasion of pathological α-synuclein in brainstem reticular nuclei and white matter lesions in a model of α-synucleinopathy. Brain Communications. 3: fcab104. PMID 34136810 DOI: 10.1093/braincomms/fcab104  0.304
2021 Ferreira N, Richner M, van der Laan A, Bergholdt Jul Christiansen I, Vægter CB, Nyengaard JR, Halliday GM, Weiss J, Giasson BI, Mackenzie IR, Jensen PH, Jan A. Prodromal neuroinvasion of pathological α-synuclein in brainstem reticular nuclei and white matter lesions in a model of α-synucleinopathy. Brain Communications. 3: fcab104. PMID 34136810 DOI: 10.1093/braincomms/fcab104  0.304
2021 Xia Y, Prokop S, Giasson BI. "Don't Phos Over Tau": recent developments in clinical biomarkers and therapies targeting tau phosphorylation in Alzheimer's disease and other tauopathies. Molecular Neurodegeneration. 16: 37. PMID 34090488 DOI: 10.1186/s13024-021-00460-5  0.817
2021 Ferreira N, Gram H, Sorrentino ZA, Gregersen E, Schmidt SI, Reimer L, Betzer C, Perez-Gozalbo C, Beltoja M, Nagaraj M, Wang J, Nowak JS, Dong M, Willén K, Cholak E, ... ... Giasson BI, et al. Multiple system atrophy-associated oligodendroglial protein p25α stimulates formation of novel α-synuclein strain with enhanced neurodegenerative potential. Acta Neuropathologica. PMID 33978813 DOI: 10.1007/s00401-021-02316-0  0.74
2021 Hass EW, Sorrentino ZA, Lloyd GM, McFarland NR, Prokop S, Giasson BI. Robust α-synuclein pathology in select brainstem neuronal populations is a potential instigator of multiple system atrophy. Acta Neuropathologica Communications. 9: 80. PMID 33941284 DOI: 10.1186/s40478-021-01173-y  0.832
2021 Krumm ZA, Lloyd GM, Francis CP, Nasif LH, Mitchell DA, Golde TE, Giasson BI, Xia Y. Precision therapeutic targets for COVID-19. Virology Journal. 18: 66. PMID 33781287 DOI: 10.1186/s12985-021-01526-y  0.767
2021 Xia Y, Nasif L, Giasson BI. Pathogenic MAPT mutations Q336H and Q336R have isoform-dependent differences in aggregation propensity and microtubule dysfunction. Journal of Neurochemistry. PMID 33772783 DOI: 10.1111/jnc.15358  0.712
2021 Croft CL, Goodwin MS, Ryu DH, Lessard CB, Tejeda G, Marrero M, Vause AR, Paterno G, Cruz PE, Lewis J, Giasson BI, Golde TE. Photodynamic studies reveal rapid formation and appreciable turnover of tau inclusions. Acta Neuropathologica. PMID 33496840 DOI: 10.1007/s00401-021-02264-9  0.353
2021 Xia Y, Chen Z, Xu G, Borchelt DR, Ayers JI, Giasson BI. Novel SOD1 monoclonal antibodies against the electrostatic loop preferentially detect misfolded SOD1 aggregates. Neuroscience Letters. 742: 135553. PMID 33346076 DOI: 10.1016/j.neulet.2020.135553  0.669
2020 Henrich MT, Geibl FF, Lakshminarasimhan H, Stegmann A, Giasson BI, Mao X, Dawson VL, Dawson TM, Oertel WH, Surmeier DJ. Determinants of seeding and spreading of α-synuclein pathology in the brain. Science Advances. 6. PMID 33177086 DOI: 10.1126/sciadv.abc2487  0.328
2020 Goodwin MS, Sinyavskaya O, Burg F, O'Neal V, Ceballos-Diaz C, Cruz PE, Lewis J, Giasson BI, Davies P, Golde TE, Levites Y. Anti-tau scFvs Targeted to the Cytoplasm or Secretory Pathway Variably Modify Pathology and Neurodegenerative Phenotypes. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 33128896 DOI: 10.1016/j.ymthe.2020.10.007  0.33
2020 Williams T, Sorrentino Z, Weinrich M, Giasson BI, Chakrabarty P. Differential cross-seeding properties of tau and α-synuclein in mouse models of tauopathy and synucleinopathy. Brain Communications. 2: fcaa090. PMID 33094280 DOI: 10.1093/braincomms/fcaa090  0.767
2020 Trejo-Lopez JA, Sorrentino ZA, Riffe CJ, Lloyd GM, Labuzan SA, Dickson DW, Yachnis AT, Prokop S, Giasson BI. Novel Monoclonal Antibodies Targeting the RRM2 domain of Human TDP-43 Protein. Neuroscience Letters. 135353. PMID 32905837 DOI: 10.1016/J.Neulet.2020.135353  0.806
2020 Butkovich LM, Houser MC, Chalermpalanupap T, Porter-Stransky KA, Iannitelli AF, Boles JS, Lloyd GM, Coomes AS, Eidson LN, De Sousa Rodrigues ME, Oliver DL, Kelly SD, Chang J, Bengoa-Vergniory N, Wade-Martins R, ... Giasson BI, et al. Transgenic mice expressing human alpha-synuclein in noradrenergic neurons develop locus coeruleus pathology and non-motor features of Parkinson's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32868457 DOI: 10.1523/Jneurosci.1468-19.2020  0.819
2020 Chu WT, DeSimone JC, Riffe CJ, Liu H, Chakrabarty P, Giasson BI, Vedam-Mai V, Vaillancourt DE. Alpha-synuclein induces progressive changes in brain microstructure and sensory-evoked brain function that precedes locomotor decline. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32669353 DOI: 10.1523/Jneurosci.0189-20.2020  0.414
2020 Xia Y, Prokop S, Gorion KM, Kim JD, Sorrentino ZA, Bell BM, Manaois AN, Chakrabarty P, Davies P, Giasson BI. Tau Ser208 phosphorylation promotes aggregation and reveals neuropathologic diversity in Alzheimer's disease and other tauopathies. Acta Neuropathologica Communications. 8: 88. PMID 32571418 DOI: 10.1186/S40478-020-00967-W  0.83
2020 Sorrentino ZA, Giasson BI. The emerging role of α-synuclein truncation in aggregation and disease. The Journal of Biological Chemistry. PMID 32424039 DOI: 10.1074/Jbc.Rev120.011743  0.794
2020 Sorrentino ZA, Hass E, Vijayaraghavan N, Gorion KM, Riffe CJ, Dhillon JS, Giasson BI. Carboxy-terminal truncation and phosphorylation of α-synuclein elongates survival in a prion-like seeding mouse model of synucleinopathy. Neuroscience Letters. 135017. PMID 32371157 DOI: 10.1016/J.Neulet.2020.135017  0.781
2020 Lloyd GM, Trejo-Lopez JA, Xia Y, McFarland KN, Lincoln SJ, Ertekin-Taner N, Giasson BI, Yachnis AT, Prokop S. Prominent amyloid plaque pathology and cerebral amyloid angiopathy in APP V717I (London) carrier - phenotypic variability in autosomal dominant Alzheimer's disease. Acta Neuropathologica Communications. 8: 31. PMID 32164763 DOI: 10.1186/S40478-020-0891-3  0.809
2020 Trejo-Lopez JA, Sorrentino ZA, Riffe CJ, Prokop S, Dickson DW, Yachnis AT, Giasson BI. Generation and Characterization of Novel Monoclonal Antibodies Targeting p62/sequestosome-1 Across Human Neurodegenerative Diseases. Journal of Neuropathology and Experimental Neurology. PMID 32106300 DOI: 10.1093/Jnen/Nlaa007  0.817
2020 Sorrentino ZA, Xia Y, Gorion KM, Hass E, Giasson BI. Carboxy-terminal truncations of mouse alpha-synuclein alter aggregation and prion-like seeding. Febs Letters. PMID 31912891 DOI: 10.1002/1873-3468.13728  0.844
2019 Sacino AN, Prokop S, Walsh MA, Adamson J, Subramony SH, Krans A, Todd PK, Giasson BI, Yachnis AT. Fragile X-associated tremor ataxia syndrome with co-occurrent progressive supranuclear palsy-like neuropathology. Acta Neuropathologica Communications. 7: 158. PMID 31665069 DOI: 10.1186/S40478-019-0818-Z  0.823
2019 Xia Y, Sorrentino ZA, Kim JD, Strang KH, Riffe CJ, Giasson BI. Impaired tau-microtubule interactions are prevalent among pathogenic tau variants arising from missense mutations. The Journal of Biological Chemistry. PMID 31653695 DOI: 10.1074/Jbc.Ra119.010178  0.829
2019 Mavroeidi P, Arvanitaki F, Karakitsou AK, Vetsi M, Kloukina I, Zweckstetter M, Giller K, Becker S, Sorrentino ZA, Giasson BI, Jensen PH, Stefanis L, Xilouri M. Correction to: Endogenous oligodendroglial alpha-synuclein and TPPP/p25α orchestrate alpha-synuclein pathology in experimental multiple system atrophy models. Acta Neuropathologica. PMID 31485733 DOI: 10.1007/s00401-019-02068-y  0.719
2019 Sorrentino ZA, Goodwin MS, Riffe CJ, Dhillon JS, Xia Y, Gorion KM, Vijayaraghavan N, McFarland KN, Golbe LI, Yachnis AT, Giasson BI. Unique α-synuclein pathology within the amygdala in Lewy body dementia: implications for disease initiation and progression. Acta Neuropathologica Communications. 7: 142. PMID 31477175 DOI: 10.1186/S40478-019-0787-2  0.84
2019 Sorrentino ZA, Giasson BI. Exploring the Peripheral Initiation of Parkinson's Disease in Animal Models. Neuron. 103: 547-549. PMID 31437447 DOI: 10.1016/J.Neuron.2019.07.031  0.759
2019 Koller EJ, De La Cruz EG, Machula T, Ibanez KR, Lin WL, Williams T, Riffe CJ, Ryu D, Strang KH, Liu X, Janus C, Golde TE, Dickson D, Giasson BI, Chakrabarty P. Combining P301L and S320F tau variants produces a novel accelerated model of tauopathy. Human Molecular Genetics. PMID 31261380 DOI: 10.1093/Hmg/Ddz151  0.457
2019 Dhillon JS, Trejo-Lopez JA, Riffe C, Levites Y, Sacino AN, Borchelt DR, Yachnis AY, Giasson BI. Comparative analyses of the in vivo induction and transmission of α-synuclein pathology in transgenic mice by MSA brain lysate and recombinant α-synuclein fibrils. Acta Neuropathologica Communications. 7: 80. PMID 31109378 DOI: 10.1186/S40478-019-0733-3  0.78
2019 Mavroeidi P, Arvanitaki F, Karakitsou AK, Vetsi M, Kloukina I, Zweckstetter M, Giller K, Becker S, Sorrentino ZA, Giasson BI, Jensen PH, Stefanis L, Xilouri M. Endogenous oligodendroglial alpha-synuclein and TPPP/p25α orchestrate alpha-synuclein pathology in experimental multiple system atrophy models. Acta Neuropathologica. PMID 31011860 DOI: 10.1007/S00401-019-02014-Y  0.789
2019 Sorrentino ZA, Giasson BI, Chakrabarty P. α-Synuclein and astrocytes: tracing the pathways from homeostasis to neurodegeneration in Lewy body disease. Acta Neuropathologica. PMID 30798354 DOI: 10.1007/S00401-019-01977-2  0.755
2019 Croft CL, Cruz PE, Ryu DH, Ceballos-Diaz C, Strang KH, Woody BM, Lin WL, Deture M, Rodríguez-Lebrón E, Dickson DW, Chakrabarty P, Levites Y, Giasson BI, Golde TE. rAAV-based brain slice culture models of Alzheimer's and Parkinson's disease inclusion pathologies. The Journal of Experimental Medicine. PMID 30770411 DOI: 10.1084/Jem.20182184  0.48
2019 Strang KH, Golde TE, Giasson BI. MAPT mutations, tauopathy, and mechanisms of neurodegeneration. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 30742061 DOI: 10.1038/S41374-019-0197-X  0.493
2019 Dhillon JS, Trejo-Lopez JA, Riffe C, McFarland NR, Hiser WM, Giasson BI, Yachnis AT. Dissecting α-synuclein inclusion pathology diversity in multiple system atrophy: implications for the prion-like transmission hypothesis. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 30737468 DOI: 10.1038/S41374-019-0198-9  0.512
2018 Strang KH, Sorrentino ZA, Riffe CJ, Gorion KM, Vijayaraghavan N, Golde TE, Giasson BI. Phosphorylation of serine 305 in tau inhibits aggregation. Neuroscience Letters. 692: 187-192. PMID 30423399 DOI: 10.1016/J.Neulet.2018.11.011  0.778
2018 Sorrentino ZA, Vijayaraghavan N, Gorion KM, Riffe CJ, Strang KH, Caldwell J, Giasson BI. Physiological carboxy-truncation of α-synuclein potentiates the prion-like formation of pathological inclusions. The Journal of Biological Chemistry. PMID 30327435 DOI: 10.1074/Jbc.Ra118.005603  0.761
2018 Hamm M, Ladd TB, Levites Y, Golde TE, Giasson BI, Lewis J. Designing antibodies against LRRK2-targeted tau epitopes. Plos One. 13: e0204367. PMID 30261006 DOI: 10.1371/Journal.Pone.0204367  0.434
2018 Sorrentino ZA, Xia Y, Funk C, Riffe CJ, Rutherford NJ, Diaz CC, Sacino AN, Price ND, Golde TE, Giasson BI, Chakrabarty P. Motor neuron loss and neuroinflammation in a model of α-synuclein-induced neurodegeneration. Neurobiology of Disease. PMID 30195075 DOI: 10.1016/J.Nbd.2018.09.005  0.809
2018 Chakrabarty P, Li A, Ladd TB, Strickland MR, Koller EJ, Burgess JD, Funk CC, Cruz PE, Allen M, Yaroshenko M, Wang X, Younkin C, Reddy J, Lohrer B, Mehrke L, ... ... Giasson BI, et al. TLR5 decoy receptor as a novel anti-amyloid therapeutic for Alzheimer's disease. The Journal of Experimental Medicine. PMID 30158114 DOI: 10.1084/Jem.20180484  0.357
2018 Pace MC, Xu G, Fromholt S, Howard J, Crosby K, Giasson BI, Lewis J, Borchelt DR. Changes in proteome solubility indicate widespread proteostatic disruption in mouse models of neurodegenerative disease. Acta Neuropathologica. PMID 30140941 DOI: 10.1007/S00401-018-1895-Y  0.477
2018 Ayers JI, Riffe CJ, Sorrentino ZA, Diamond J, Fagerli E, Brooks M, Galaleldeen A, Hart PJ, Giasson BI. Localized induction of wild-type and mutant alpha-synuclein aggregation reveals propagation along neuroanatomical tracts. Journal of Virology. PMID 29976670 DOI: 10.1128/Jvi.00586-18  0.773
2018 Rayaprolu S, Seven YB, Howard J, Duffy C, Altshuler M, Moloney C, Giasson BI, Lewis J. Partial loss of ATP13A2 causes selective gliosis independent of robust lipofuscinosis. Molecular and Cellular Neurosciences. PMID 29859891 DOI: 10.1016/J.Mcn.2018.05.009  0.433
2018 Pace MC, Xu G, Fromholt S, Howard J, Giasson BI, Lewis J, Borchelt DR. Differential induction of mutant SOD1 misfolding and aggregation by tau and α-synuclein pathology. Molecular Neurodegeneration. 13: 23. PMID 29776378 DOI: 10.1186/S13024-018-0253-9  0.436
2018 Croft CL, Moore BD, Ran Y, Chakrabarty P, Levites Y, Golde TE, Giasson BI. Novel monoclonal antibodies targeting the microtubule-binding domain of human tau. Plos One. 13: e0195211. PMID 29608591 DOI: 10.1371/Journal.Pone.0195211  0.472
2018 Strang KH, Croft CL, Sorrentino ZA, Chakrabarty P, Golde TE, Giasson BI. Distinct differences in prion-like seeding and aggregation between Tau protein variants provide mechanistic insights into tauopathies. The Journal of Biological Chemistry. 293: 4579. PMID 29572329 DOI: 10.1074/jbc.AAC118.002657  0.742
2018 Phan HTM, Bartz JC, Ayers J, Giasson BI, Schubert M, Rodenhausen KB, Kananizadeh N, Li Y, Bartelt-Hunt SL. Adsorption and decontamination of α-synuclein from medically and environmentally-relevant surfaces. Colloids and Surfaces. B, Biointerfaces. 166: 98-107. PMID 29550546 DOI: 10.1016/J.Colsurfb.2018.03.011  0.327
2018 Giraldo G, Brooks M, Giasson BI, Janus C. Locomotor differences in mice expressing wild-type human α-synuclein. Neurobiology of Aging. 65: 140-148. PMID 29477894 DOI: 10.1016/J.Neurobiolaging.2018.01.020  0.425
2017 Strang KH, Croft CL, Sorrentino ZA, Chakrabarty P, Golde TE, Giasson BI. Distinct differences in prion-like seeding and aggregation between tau protein variants provide mechanistic insights into tauopathies. The Journal of Biological Chemistry. PMID 29259137 DOI: 10.1074/Jbc.M117.815357  0.788
2017 Tayebi N, Parisiadou L, Berhe B, Gonzalez AN, Serra-Vinardell J, Tamargo RJ, Maniwang E, Sorrentino Z, Fujiwara H, Grey RJ, Hassan S, Blech-Hermoni YN, Chen C, McGlinchey R, Makariou-Pikis C, ... ... Giasson BI, et al. Glucocerebrosidase haploinsufficiency in A53T α-synuclein mice impacts disease onset and course. Molecular Genetics and Metabolism. 122: 198-208. PMID 29173981 DOI: 10.1016/J.Ymgme.2017.11.001  0.767
2017 Rutherford NJ, Dhillon JS, Riffe CJ, Howard JK, Brooks M, Giasson BI. Comparison of the in vivo induction and transmission of α-synuclein pathology by mutant α-synuclein fibril seeds in transgenic mice. Human Molecular Genetics. PMID 29036344 DOI: 10.1093/Hmg/Ddx371  0.435
2017 Rutherford NJ, Brooks M, Riffe CJ, Gorion KM, Howard JK, Dhillon JS, Giasson BI. Prion-like transmission of α-synuclein pathology in the context of an NFL null background. Neuroscience Letters. PMID 28964772 DOI: 10.1016/J.Neulet.2017.09.054  0.458
2017 Dhillon JS, Riffe C, Moore BD, Ran Y, Chakrabarty P, Golde TE, Giasson BI. A novel panel of α-synuclein antibodies reveal distinctive staining profiles in synucleinopathies. Plos One. 12: e0184731. PMID 28910367 DOI: 10.1371/Journal.Pone.0184731  0.447
2017 Park HJ, Ryu D, Parmar M, Giasson BI, McFarland NR. The ER retention protein RER1 promotes alpha-synuclein degradation via the proteasome. Plos One. 12: e0184262. PMID 28877262 DOI: 10.1371/Journal.Pone.0184262  0.453
2017 Strang KH, Goodwin MS, Riffe C, Moore BD, Chakrabarty P, Levites Y, Golde TE, Giasson BI. Generation and characterization of new monoclonal antibodies targeting the PHF1 and AT8 epitopes on human tau. Acta Neuropathologica Communications. 5: 58. PMID 28760159 DOI: 10.1186/S40478-017-0458-0  0.486
2017 Sorrentino ZA, Brooks MMT, Hudson V, Rutherford NJ, Golde TE, Giasson BI, Chakrabarty P. Intrastriatal injection of α-synuclein can lead to widespread synucleinopathy independent of neuroanatomic connectivity. Molecular Neurodegeneration. 12: 40. PMID 28552073 DOI: 10.1186/S13024-017-0182-Z  0.758
2017 Ayers JI, Giasson BI, Borchelt DR. Prion-like Spreading in Tauopathies. Biological Psychiatry. PMID 28506438 DOI: 10.1016/J.Biopsych.2017.04.003  0.493
2017 Koller EJ, Brooks MM, Golde TE, Giasson BI, Chakrabarty P. Inflammatory pre-conditioning restricts the seeded induction of α-synuclein pathology in wild type mice. Molecular Neurodegeneration. 12: 1. PMID 28049533 DOI: 10.1186/S13024-016-0142-Z  0.379
2017 Croft CL, Cruz PE, Goodwin MS, Ceballos-Diaz C, Strang K, Chakrabarty P, Levites Y, Giasson BI, Golde TE. [P4-094]: TARGETING TAU AGGREGATION IN BRAIN SLICE CULTURE MODELS OF TAUOPATHIES Alzheimer's & Dementia. 13: P1294-P1294. DOI: 10.1016/J.Jalz.2017.06.1959  0.354
2016 Ayers JI, Brooks MM, Rutherford NJ, Howard JK, Sorrentino ZA, Riffe CJ, Giasson BI. Robust CNS pathology in transgenic mice following peripheral injection of α-synuclein fibrils. Journal of Virology. PMID 27852849 DOI: 10.1128/Jvi.02095-16  0.748
2016 Rutherford NJ, Brooks M, Giasson BI. Novel antibodies to phosphorylated α-synuclein serine 129 and NFL serine 473 demonstrate the close molecular homology of these epitopes. Acta Neuropathologica Communications. 4: 80. PMID 27503460 DOI: 10.1186/S40478-016-0357-9  0.365
2016 Sacino AN, Brooks MM, Chakrabarty P, Saha K, Khoshbouei H, Golde TE, Giasson BI. Proteolysis of α-Synuclein Fibrils in the Lysosomal Pathway Limits Induction of Inclusion Pathology. Journal of Neurochemistry. PMID 27424880 DOI: 10.1111/Jnc.13743  0.771
2015 Uchihara T, Giasson BI, Paulus W. Propagation of Aβ, tau and α-synuclein pathology between experimental models and human reality: prions, propagons and propaganda. Acta Neuropathologica. PMID 26715564 DOI: 10.1007/S00401-015-1517-X  0.455
2015 Sacino AN, Ayers JI, Brooks MM, Chakrabarty P, Hudson VJ, Howard JK, Golde TE, Giasson BI, Borchelt DR. Non-prion-type transmission in A53T α-synuclein transgenic mice: a normal component of spinal homogenates from naïve non-transgenic mice induces robust α-synuclein pathology. Acta Neuropathologica. PMID 26541429 DOI: 10.1007/S00401-015-1505-1  0.746
2015 Uchihara T, Giasson BI. Propagation of alpha-synuclein pathology: hypotheses, discoveries, and yet unresolved questions from experimental and human brain studies. Acta Neuropathologica. PMID 26446103 DOI: 10.1007/S00401-015-1485-1  0.454
2015 Rutherford NJ, Sacino AN, Brooks M, Ceballos-Diaz C, Ladd TB, Howard JK, Golde TE, Giasson BI. Studies of lipopolysaccharide effects on the induction of α-synuclein pathology by exogenous fibrils in transgenic mice. Molecular Neurodegeneration. 10: 32. PMID 26223783 DOI: 10.1186/S13024-015-0029-4  0.758
2015 Hamm M, Bailey R, Shaw G, Yen SH, Lewis J, Giasson BI. Physiologically relevant factors influence tau phosphorylation by leucine-rich repeat kinase 2. Journal of Neuroscience Research. PMID 26123245 DOI: 10.1002/Jnr.23614  0.448
2015 Chakrabarty P, Hudson Iii VJ, Sacino AN, Brooks MM, D'Alton S, Lewis J, Golde TE, Giasson BI. Inefficient induction and spread of seeded tau pathology in P301L mouse model of tauopathy suggests inherent physiological barriers to transmission. Acta Neuropathologica. 130: 303-5. PMID 25982997 DOI: 10.1007/S00401-015-1444-X  0.778
2015 Rutherford NJ, Giasson BI. The A53E α-synuclein pathological mutation demonstrates reduced aggregation propensity in vitro and in cell culture. Neuroscience Letters. 597: 43-8. PMID 25892596 DOI: 10.1016/J.Neulet.2015.04.022  0.405
2015 Chakrabarty P, Brooks M, Hudson V, Levites Y, Giasson BI, Golde T. O2-05-01: IL-10 modifies disease progression and pathology in a mouse model of alpha synucleinopathy Alzheimer's & Dementia. 11: P182-P183. DOI: 10.1016/J.Jalz.2015.07.154  0.355
2014 Fishbein I, Kuo YM, Giasson BI, Nussbaum RL. Augmentation of phenotype in a transgenic Parkinson mouse heterozygous for a Gaucher mutation. Brain : a Journal of Neurology. 137: 3235-47. PMID 25351739 DOI: 10.1093/Brain/Awu291  0.442
2014 Sacino AN, Brooks M, McKinney AB, Thomas MA, Shaw G, Golde TE, Giasson BI. Brain injection of α-synuclein induces multiple proteinopathies, gliosis, and a neuronal injury marker. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 12368-78. PMID 25209277 DOI: 10.1523/Jneurosci.2102-14.2014  0.768
2014 Sacino AN, Brooks M, Thomas MA, McKinney AB, Lee S, Regenhardt RW, McGarvey NH, Ayers JI, Notterpek L, Borchelt DR, Golde TE, Giasson BI. Intramuscular injection of α-synuclein induces CNS α-synuclein pathology and a rapid-onset motor phenotype in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 111: 10732-7. PMID 25002524 DOI: 10.1073/Pnas.1321785111  0.771
2014 Rutherford NJ, Moore BD, Golde TE, Giasson BI. Divergent effects of the H50Q and G51D SNCA mutations on the aggregation of α-synuclein. Journal of Neurochemistry. 131: 859-67. PMID 24984882 DOI: 10.1111/Jnc.12806  0.446
2014 Guo L, Giasson BI, Glavis-Bloom A, Brewer MD, Shorter J, Gitler AD, Yang X. A cellular system that degrades misfolded proteins and protects against neurodegeneration. Molecular Cell. 55: 15-30. PMID 24882209 DOI: 10.1016/J.Molcel.2014.04.030  0.363
2014 Sacino AN, Brooks M, Thomas MA, McKinney AB, McGarvey NH, Rutherford NJ, Ceballos-Diaz C, Robertson J, Golde TE, Giasson BI. Amyloidogenic α-synuclein seeds do not invariably induce rapid, widespread pathology in mice. Acta Neuropathologica. 127: 645-65. PMID 24659240 DOI: 10.1007/S00401-014-1268-0  0.756
2014 Escobar VD, Kuo YM, Orrison BM, Giasson BI, Nussbaum RL. Transgenic mice expressing S129 phosphorylation mutations in α-synuclein. Neuroscience Letters. 563: 96-100. PMID 24486885 DOI: 10.1016/J.Neulet.2014.01.033  0.473
2014 Gould N, Mor DE, Lightfoot R, Malkus K, Giasson B, Ischiropoulos H. Evidence of native α-synuclein conformers in the human brain Journal of Biological Chemistry. 289: 7929-7934. PMID 24474688 DOI: 10.1074/Jbc.C113.538249  0.361
2014 Ren Y, Sahara N, Giasson B, Lewis J. Tauopathy Mouse Models Movement Disorders: Genetics and Models: Second Edition. 849-855. DOI: 10.1016/B978-0-12-405195-9.00055-X  0.396
2013 Musiek ES, Lim MM, Yang G, Bauer AQ, Qi L, Lee Y, Roh JH, Ortiz-Gonzalez X, Dearborn JT, Culver JP, Herzog ED, Hogenesch JB, Wozniak DF, Dikranian K, Giasson BI, et al. Circadian clock proteins regulate neuronal redox homeostasis and neurodegeneration. The Journal of Clinical Investigation. 123: 5389-400. PMID 24270424 DOI: 10.1172/Jci70317  0.334
2013 Sacino AN, Brooks M, McGarvey NH, McKinney AB, Thomas MA, Levites Y, Ran Y, Golde TE, Giasson BI. Induction of CNS α-synuclein pathology by fibrillar and non-amyloidogenic recombinant α-synuclein. Acta Neuropathologica Communications. 1: 38. PMID 24252149 DOI: 10.1186/2051-5960-1-38  0.784
2013 Bailey RM, Covy JP, Melrose HL, Rousseau L, Watkinson R, Knight J, Miles S, Farrer MJ, Dickson DW, Giasson BI, Lewis J. LRRK2 phosphorylates novel tau epitopes and promotes tauopathy. Acta Neuropathologica. 126: 809-27. PMID 24113872 DOI: 10.1007/S00401-013-1188-4  0.814
2013 Rutherford NJ, Lewis J, Clippinger AK, Thomas MA, Adamson J, Cruz PE, Cannon A, Xu G, Golde TE, Shaw G, Borchelt DR, Giasson BI. Unbiased screen reveals ubiquilin-1 and -2 highly associated with huntingtin inclusions. Brain Research. 1524: 62-73. PMID 23774650 DOI: 10.1016/J.Brainres.2013.06.006  0.51
2013 Sacino AN, Thomas MA, Ceballos-Diaz C, Cruz PE, Rosario AM, Lewis J, Giasson BI, Golde TE. Conformational templating of α-synuclein aggregates in neuronal-glial cultures. Molecular Neurodegeneration. 8: 17. PMID 23714769 DOI: 10.1186/1750-1326-8-17  0.776
2013 Clippinger AK, D'Alton S, Lin WL, Gendron TF, Howard J, Borchelt DR, Cannon A, Carlomagno Y, Chakrabarty P, Cook C, Golde TE, Levites Y, Ranum L, Schultheis PJ, Xu G, ... ... Giasson B, et al. Robust cytoplasmic accumulation of phosphorylated TDP-43 in transgenic models of tauopathy. Acta Neuropathologica. 126: 39-50. PMID 23666556 DOI: 10.1007/S00401-013-1123-8  0.509
2013 Golde TE, Borchelt DR, Giasson BI, Lewis J. Thinking laterally about neurodegenerative proteinopathies. The Journal of Clinical Investigation. 123: 1847-55. PMID 23635781 DOI: 10.1172/Jci66029  0.418
2013 Nalls MA, Duran R, Lopez G, Kurzawa-Akanbi M, McKeith IG, Chinnery PF, Morris CM, Theuns J, Crosiers D, Cras P, Engelborghs S, De Deyn PP, Van Broeckhoven C, Mann DM, Snowden J, ... ... Giasson BI, et al. A multicenter study of glucocerebrosidase mutations in dementia with Lewy bodies. Jama Neurology. 70: 727-35. PMID 23588557 DOI: 10.1001/Jamaneurol.2013.1925  0.473
2013 Schultheis PJ, Fleming SM, Clippinger AK, Lewis J, Tsunemi T, Giasson B, Dickson DW, Mazzulli JR, Bardgett ME, Haik KL, Ekhator O, Chava AK, Howard J, Gannon M, Hoffman E, et al. Atp13a2-deficient mice exhibit neuronal ceroid lipofuscinosis, limited α-synuclein accumulation and age-dependent sensorimotor deficits. Human Molecular Genetics. 22: 2067-82. PMID 23393156 DOI: 10.1093/Hmg/Ddt057  0.449
2012 Sacino AN, Giasson BI. Does a prion-like mechanism play a major role in the apparent spread of α-synuclein pathology? Alzheimer's Research & Therapy. 4: 48. PMID 23245350 DOI: 10.1186/Alzrt151  0.803
2012 Covy JP, Waxman EA, Giasson BI. Characterization of cellular protective effects of ATP13A2/PARK9 expression and alterations resulting from pathogenic mutants. Journal of Neuroscience Research. 90: 2306-16. PMID 22847264 DOI: 10.1002/Jnr.23112  0.781
2012 Emmer KL, Covy JP, Giasson BI. Studies of protein aggregation in A53T α-synuclein transgenic, Tg2576 transgenic, and P246L presenilin-1 knock-in cross bred mice. Neuroscience Letters. 507: 137-42. PMID 22188655 DOI: 10.1016/J.Neulet.2011.12.005  0.823
2011 Emmer KL, Waxman EA, Covy JP, Giasson BI. E46K human alpha-synuclein transgenic mice develop Lewy-like and tau pathology associated with age-dependent, detrimental motor impairment. The Journal of Biological Chemistry. 286: 35104-18. PMID 21846727 DOI: 10.1074/Jbc.M111.247965  0.839
2011 Waxman EA, Giasson BI. Induction of intracellular tau aggregation is promoted by α-synuclein seeds and provides novel insights into the hyperphosphorylation of tau. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 7604-18. PMID 21613474 DOI: 10.1523/Jneurosci.0297-11.2011  0.522
2011 Covy JP, Giasson BI. α-Synuclein, leucine-rich repeat kinase-2, and manganese in the pathogenesis of Parkinson disease. Neurotoxicology. 32: 622-9. PMID 21238487 DOI: 10.1016/J.Neuro.2011.01.003  0.805
2011 Waxman EA, Giasson BI. Characterization of kinases involved in the phosphorylation of aggregated α-synuclein. Journal of Neuroscience Research. 89: 231-47. PMID 21162130 DOI: 10.1002/Jnr.22537  0.425
2010 Goker-Alpan O, Stubblefield BK, Giasson BI, Sidransky E. Glucocerebrosidase is present in α-synuclein inclusions in Lewy body disorders. Acta Neuropathologica. 120: 641-9. PMID 20838799 DOI: 10.1007/S00401-010-0741-7  0.422
2010 Ramsey CP, Giasson BI. L10p and P158DEL DJ-1 mutations cause protein instability, aggregation, and dimerization impairments. Journal of Neuroscience Research. 88: 3111-24. PMID 20806408 DOI: 10.1002/Jnr.22477  0.784
2010 Covy JP, Giasson BI. The G2019S pathogenic mutation disrupts sensitivity of leucine-rich repeat kinase 2 to manganese kinase inhibition. Journal of Neurochemistry. 115: 36-46. PMID 20626563 DOI: 10.1111/J.1471-4159.2010.06894.X  0.771
2010 Tsika E, Moysidou M, Guo J, Cushman M, Gannon P, Sandaltzopoulos R, Giasson BI, Krainc D, Ischiropoulos H, Mazzulli JR. Distinct region-specific alpha-synuclein oligomers in A53T transgenic mice: implications for neurodegeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 3409-18. PMID 20203200 DOI: 10.1523/Jneurosci.4977-09.2010  0.529
2010 Waxman EA, Giasson BI. A novel, high-efficiency cellular model of fibrillar alpha-synuclein inclusions and the examination of mutations that inhibit amyloid formation. Journal of Neurochemistry. 113: 374-88. PMID 20132485 DOI: 10.1111/J.1471-4159.2010.06592.X  0.467
2010 Kuo YM, Li Z, Jiao Y, Gaborit N, Pani AK, Orrison BM, Bruneau BG, Giasson BI, Smeyne RJ, Gershon MD, Nussbaum RL. Extensive enteric nervous system abnormalities in mice transgenic for artificial chromosomes containing Parkinson disease-associated alpha-synuclein gene mutations precede central nervous system changes. Human Molecular Genetics. 19: 1633-50. PMID 20106867 DOI: 10.1093/Hmg/Ddq038  0.469
2010 Ramsey CP, Tsika E, Ischiropoulos H, Giasson BI. DJ-1 deficient mice demonstrate similar vulnerability to pathogenic Ala53Thr human alpha-syn toxicity. Human Molecular Genetics. 19: 1425-37. PMID 20089532 DOI: 10.1093/Hmg/Ddq017  0.829
2010 Ramsey CP, Giasson BI. Identification and characterization of a novel endogenous murine parkin mutation. Journal of Neurochemistry. 113: 402-17. PMID 20089136 DOI: 10.1111/J.1471-4159.2010.06605.X  0.802
2010 Waxman EA, Emmer KL, Giasson BI. Residue Glu83 plays a major role in negatively regulating alpha-synuclein amyloid formation. Biochemical and Biophysical Research Communications. 391: 1415-20. PMID 20026050 DOI: 10.1016/J.Bbrc.2009.12.079  0.479
2009 Waxman EA, Mazzulli JR, Giasson BI. Characterization of hydrophobic residue requirements for alpha-synuclein fibrillization. Biochemistry. 48: 9427-36. PMID 19722699 DOI: 10.1021/Bi900539P  0.485
2009 Waxman EA, Covy JP, Bukh I, Li X, Dawson TM, Giasson BI. Leucine-rich repeat kinase 2 expression leads to aggresome formation that is not associated with alpha-synuclein inclusions. Journal of Neuropathology and Experimental Neurology. 68: 785-96. PMID 19535993 DOI: 10.1097/Nen.0B013E3181Aaf4Fd  0.834
2009 Covy JP, Giasson BI. Identification of compounds that inhibit the kinase activity of leucine-rich repeat kinase 2. Biochemical and Biophysical Research Communications. 378: 473-7. PMID 19027715 DOI: 10.1016/J.Bbrc.2008.11.048  0.781
2009 Covy JP, Yuan W, Waxman EA, Hurtig HI, Van Deerlin VM, Giasson BI. Clinical and pathological characteristics of patients with leucine-rich repeat kinase-2 mutations. Movement Disorders : Official Journal of the Movement Disorder Society. 24: 32-9. PMID 19006185 DOI: 10.1002/Mds.22096  0.791
2009 Waxman EA, Giasson BI. Molecular mechanisms of alpha-synuclein neurodegeneration. Biochimica Et Biophysica Acta. 1792: 616-24. PMID 18955133 DOI: 10.1016/J.Bbadis.2008.09.013  0.488
2009 Covy JP, Giasson BI. Corrigendum to "Identification of compounds that inhibit the kinase activity of leucine-rich repeat kinase 2" [Biochem. Biophys. Res. Commun. 378 (2009) 473-477] (DOI:10.1016/j.bbrc.2008.11.048) Biochemical and Biophysical Research Communications. 387: 419-420. DOI: 10.1016/J.Bbrc.2009.06.066  0.75
2008 Ramsey CP, Giasson BI. The E163K DJ-1 mutant shows specific antioxidant deficiency. Brain Research. 1239: 1-11. PMID 18822273 DOI: 10.1016/J.Brainres.2008.09.009  0.808
2008 Waxman EA, Giasson BI. Specificity and regulation of casein kinase-mediated phosphorylation of alpha-synuclein. Journal of Neuropathology and Experimental Neurology. 67: 402-16. PMID 18451726 DOI: 10.1097/Nen.0B013E3186Fc995  0.451
2008 Waxman EA, Duda JE, Giasson BI. Characterization of antibodies that selectively detect alpha-synuclein in pathological inclusions. Acta Neuropathologica. 116: 37-46. PMID 18414880 DOI: 10.1007/S00401-008-0375-1  0.458
2008 Giasson BI, Van Deerlin VM. Mutations in LRRK2 as a cause of Parkinson's disease. Neuro-Signals. 16: 99-105. PMID 18097165 DOI: 10.1159/000109764  0.423
2008 Song WL, Lawson JA, Reilly D, Rokach J, Chang CT, Giasson B, FitzGerald GA. Neurofurans, novel indices of oxidant stress derived from docosahexaenoic acid. The Journal of Biological Chemistry. 283: 6-16. PMID 17921521 DOI: 10.1074/Jbc.M706124200  0.347
2008 Klegeris A, Pelech S, Giasson BI, Maguire J, Zhang H, McGeer EG, McGeer PL. Alpha-synuclein activates stress signaling protein kinases in THP-1 cells and microglia. Neurobiology of Aging. 29: 739-52. PMID 17166628 DOI: 10.1016/J.Neurobiolaging.2006.11.013  0.425
2007 Ramsey CP, Giasson BI. Role of mitochondrial dysfunction in Parkinson's disease: Implications for treatment. Drugs & Aging. 24: 95-105. PMID 17313198 DOI: 10.2165/00002512-200724020-00002  0.795
2007 Norris EH, Uryu K, Leight S, Giasson BI, Trojanowski JQ, Lee VM. Pesticide exposure exacerbates alpha-synucleinopathy in an A53T transgenic mouse model. The American Journal of Pathology. 170: 658-66. PMID 17255333 DOI: 10.2353/Ajpath.2007.060359  0.78
2006 Beal MF, Bossy-Wetzel E, Finkbeiner S, Fiskum G, Giasson B, Johnson C, Khachaturian ZS, Lee VM, Nicholls D, Reddy H, Reynolds I, Teplow DB, Thal LJ, Trojanowski JQ, Walsh DM, et al. Common threads in neurodegenerative disorders of aging. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 2: 322-6. PMID 19595906 DOI: 10.1016/J.Jalz.2006.08.008  0.623
2006 Klegeris A, Giasson BI, Zhang H, Maguire J, Pelech S, McGeer PL. Alpha-synuclein and its disease-causing mutants induce ICAM-1 and IL-6 in human astrocytes and astrocytoma cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 2000-8. PMID 17012252 DOI: 10.1096/Fj.06-6183Com  0.425
2006 Mazzulli JR, Mishizen AJ, Giasson BI, Lynch DR, Thomas SA, Nakashima A, Nagatsu T, Ota A, Ischiropoulos H. Cytosolic catechols inhibit alpha-synuclein aggregation and facilitate the formation of intracellular soluble oligomeric intermediates. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 10068-78. PMID 17005870 DOI: 10.1523/Jneurosci.0896-06.2006  0.459
2006 Goker-Alpan O, Giasson BI, Eblan MJ, Nguyen J, Hurtig HI, Lee VM, Trojanowski JQ, Sidransky E. Glucocerebrosidase mutations are an important risk factor for Lewy body disorders. Neurology. 67: 908-10. PMID 16790605 DOI: 10.1212/01.Wnl.0000230215.41296.18  0.635
2006 Uryu K, Richter-Landsberg C, Welch W, Sun E, Goldbaum O, Norris EH, Pham CT, Yazawa I, Hilburger K, Micsenyi M, Giasson BI, Bonini NM, Lee VM, Trojanowski JQ. Convergence of heat shock protein 90 with ubiquitin in filamentous alpha-synuclein inclusions of alpha-synucleinopathies. The American Journal of Pathology. 168: 947-61. PMID 16507910 DOI: 10.2353/Ajpath.2006.050770  0.768
2006 Giasson BI, Covy JP, Bonini NM, Hurtig HI, Farrer MJ, Trojanowski JQ, Van Deerlin VM. Biochemical and pathological characterization of Lrrk2. Annals of Neurology. 59: 315-22. PMID 16437584 DOI: 10.1002/Ana.20791  0.824
2006 Duda JE, Giasson BI, Lee VM, Trojanowski JQ. Is the Initial Insult in Parkinson's Disease and Dementia with Lewy Bodies a Neuritic Dystrophy? Annals of the New York Academy of Sciences. 991: 295-297. DOI: 10.1111/J.1749-6632.2003.Tb07488.X  0.611
2006 Covy JP, Van Deerlin VM, Giasson BI. Lack of evidence for Lrrk2 in α-synuclein pathological inclusions [4] Annals of Neurology. 60: 618-619. DOI: 10.1002/Ana.21029  0.798
2005 Bonini NM, Giasson BI. Snaring the function of alpha-synuclein. Cell. 123: 359-61. PMID 16269324 DOI: 10.1016/J.Cell.2005.10.017  0.4
2005 Meulener MC, Graves CL, Sampathu DM, Armstrong-Gold CE, Bonini NM, Giasson BI. DJ-1 is present in a large molecular complex in human brain tissue and interacts with alpha-synuclein. Journal of Neurochemistry. 93: 1524-32. PMID 15935068 DOI: 10.1111/J.1471-4159.2005.03145.X  0.834
2005 Mishizen-Eberz AJ, Norris EH, Giasson BI, Hodara R, Ischiropoulos H, Lee VM, Trojanowski JQ, Lynch DR. Cleavage of alpha-synuclein by calpain: potential role in degradation of fibrillized and nitrated species of alpha-synuclein. Biochemistry. 44: 7818-29. PMID 15909996 DOI: 10.1021/Bi047846Q  0.764
2005 Norris EH, Giasson BI. Role of oxidative damage in protein aggregation associated with Parkinson's disease and related disorders. Antioxidants & Redox Signaling. 7: 672-84. PMID 15890012 DOI: 10.1089/Ars.2005.7.672  0.755
2005 Liu CW, Giasson BI, Lewis KA, Lee VM, Demartino GN, Thomas PJ. A precipitating role for truncated alpha-synuclein and the proteasome in alpha-synuclein aggregation: implications for pathogenesis of Parkinson disease. The Journal of Biological Chemistry. 280: 22670-8. PMID 15840579 DOI: 10.1074/Jbc.M501508200  0.646
2005 Norris EH, Giasson BI, Hodara R, Xu S, Trojanowski JQ, Ischiropoulos H, Lee VM. Reversible inhibition of alpha-synuclein fibrillization by dopaminochrome-mediated conformational alterations. The Journal of Biological Chemistry. 280: 21212-9. PMID 15817478 DOI: 10.1074/Jbc.M412621200  0.754
2005 Yazawa I, Giasson BI, Sasaki R, Zhang B, Joyce S, Uryu K, Trojanowski JQ, Lee VM. Mouse model of multiple system atrophy alpha-synuclein expression in oligodendrocytes causes glial and neuronal degeneration. Neuron. 45: 847-59. PMID 15797547 DOI: 10.1016/J.Neuron.2005.01.032  0.626
2005 Greenbaum EA, Graves CL, Mishizen-Eberz AJ, Lupoli MA, Lynch DR, Englander SW, Axelsen PH, Giasson BI. The E46K mutation in alpha-synuclein increases amyloid fibril formation. The Journal of Biological Chemistry. 280: 7800-7. PMID 15632170 DOI: 10.1074/Jbc.M411638200  0.45
2004 Giasson BI. Mitochondrial injury: a hot spot for parkinsonism and Parkinson's disease? Science of Aging Knowledge Environment : Sage Ke. 2004: pe42. PMID 15576821 DOI: 10.1126/Sageke.2004.48.Pe42  0.406
2004 Hodara R, Norris EH, Giasson BI, Mishizen-Eberz AJ, Lynch DR, Lee VM, Ischiropoulos H. Functional consequences of alpha-synuclein tyrosine nitration: diminished binding to lipid vesicles and increased fibril formation. The Journal of Biological Chemistry. 279: 47746-53. PMID 15364911 DOI: 10.1074/Jbc.M408906200  0.734
2004 Kotzbauer PT, Giasson BI, Kravitz AV, Golbe LI, Mark MH, Trojanowski JQ, Lee VM. Fibrillization of alpha-synuclein and tau in familial Parkinson's disease caused by the A53T alpha-synuclein mutation. Experimental Neurology. 187: 279-88. PMID 15144854 DOI: 10.1016/J.Expneurol.2004.01.007  0.658
2004 Wilson CA, Murphy DD, Giasson BI, Zhang B, Trojanowski JQ, Lee VM. Degradative organelles containing mislocalized alpha-and beta-synuclein proliferate in presenilin-1 null neurons. The Journal of Cell Biology. 165: 335-46. PMID 15123735 DOI: 10.1083/Jcb.200403061  0.734
2004 Norris EH, Giasson BI, Lee VM. Alpha-synuclein: normal function and role in neurodegenerative diseases. Current Topics in Developmental Biology. 60: 17-54. PMID 15094295 DOI: 10.1016/S0070-2153(04)60002-0  0.776
2004 Lee VM, Giasson BI, Trojanowski JQ. More than just two peas in a pod: common amyloidogenic properties of tau and alpha-synuclein in neurodegenerative diseases. Trends in Neurosciences. 27: 129-34. PMID 15036877 DOI: 10.1016/J.Tins.2004.01.007  0.693
2004 Norris EH, Giasson BI, Xu S, Hodara R, Trojanowski JQ, Ischiropoulos H, Lee V. P1-302 Implications of dopamine-induced modificationsof alpha-synuclein protein in the pathogenesis of Parkinson's disease Neurobiology of Aging. 25: S182. DOI: 10.1016/S0197-4580(04)80615-8  0.765
2004 Giasson BI, Lee VMY, Trojanowski JQ. Animal models of neurodegenerative dementing disorders other than Alzheimer's disease Clinical Neuroscience Research. 3: 427-436. DOI: 10.1016/J.Cnr.2004.04.008  0.55
2003 Uryu K, Giasson BI, Longhi L, Martinez D, Murray I, Conte V, Nakamura M, Saatman K, Talbot K, Horiguchi T, McIntosh T, Lee VM, Trojanowski JQ. Age-dependent synuclein pathology following traumatic brain injury in mice. Experimental Neurology. 184: 214-24. PMID 14637093 DOI: 10.1016/S0014-4886(03)00245-0  0.777
2003 Giasson BI, Lee VM, Trojanowski JQ. Interactions of amyloidogenic proteins. Neuromolecular Medicine. 4: 49-58. PMID 14528052 DOI: 10.1385/Nmm:4:1-2:49  0.688
2003 Pawlyk AC, Giasson BI, Sampathu DM, Perez FA, Lim KL, Dawson VL, Dawson TM, Palmiter RD, Trojanowski JQ, Lee VM. Novel monoclonal antibodies demonstrate biochemical variation of brain parkin with age. The Journal of Biological Chemistry. 278: 48120-8. PMID 12972409 DOI: 10.1074/Jbc.M306889200  0.81
2003 Crystal AS, Giasson BI, Crowe A, Kung MP, Zhuang ZP, Trojanowski JQ, Lee VM. A comparison of amyloid fibrillogenesis using the novel fluorescent compound K114. Journal of Neurochemistry. 86: 1359-68. PMID 12950445 DOI: 10.1046/J.1471-4159.2003.01949.X  0.812
2003 Horiguchi T, Uryu K, Giasson BI, Ischiropoulos H, LightFoot R, Bellmann C, Richter-Landsberg C, Lee VM, Trojanowski JQ. Nitration of tau protein is linked to neurodegeneration in tauopathies. The American Journal of Pathology. 163: 1021-31. PMID 12937143 DOI: 10.1016/S0002-9440(10)63462-1  0.632
2003 Mishizen-Eberz AJ, Guttmann RP, Giasson BI, Day GA, Hodara R, Ischiropoulos H, Lee VM, Trojanowski JQ, Lynch DR. Distinct cleavage patterns of normal and pathologic forms of alpha-synuclein by calpain I in vitro. Journal of Neurochemistry. 86: 836-47. PMID 12887682 DOI: 10.1046/J.1471-4159.2003.01878.X  0.631
2003 Giasson BI, Lee VM. Are ubiquitination pathways central to Parkinson's disease? Cell. 114: 1-8. PMID 12859888 DOI: 10.1016/S0092-8674(03)00509-9  0.546
2003 Murray IV, Giasson BI, Quinn SM, Koppaka V, Axelsen PH, Ischiropoulos H, Trojanowski JQ, Lee VM. Role of alpha-synuclein carboxy-terminus on fibril formation in vitro. Biochemistry. 42: 8530-40. PMID 12859200 DOI: 10.1021/Bi027363R  0.764
2003 Norris EH, Giasson BI, Ischiropoulos H, Lee VM. Effects of oxidative and nitrative challenges on alpha-synuclein fibrillogenesis involve distinct mechanisms of protein modifications. The Journal of Biological Chemistry. 278: 27230-40. PMID 12857790 DOI: 10.1074/Jbc.M212436200  0.745
2003 Sampathu DM, Giasson BI, Pawlyk AC, Trojanowski JQ, Lee VM. Ubiquitination of alpha-synuclein is not required for formation of pathological inclusions in alpha-synucleinopathies. The American Journal of Pathology. 163: 91-100. PMID 12819014 DOI: 10.1016/S0002-9440(10)63633-4  0.822
2003 Giasson BI, Mabon ME, Duda JE, Montine TJ, Robertson D, Hurtig HI, Lee VM, Trojanowski JQ. Tau and 14-3-3 in glial cytoplasmic inclusions of multiple system atrophy. Acta Neuropathologica. 106: 243-50. PMID 12811584 DOI: 10.1007/S00401-003-0726-X  0.66
2003 Fung KM, Rorke LB, Giasson B, Lee VM, Trojanowski JQ. Expression of alpha-, beta-, and gamma-synuclein in glial tumors and medulloblastomas. Acta Neuropathologica. 106: 167-75. PMID 12783249 DOI: 10.1007/S00401-003-0718-X  0.694
2003 Giasson BI, Forman MS, Higuchi M, Golbe LI, Graves CL, Kotzbauer PT, Trojanowski JQ, Lee VM. Initiation and synergistic fibrillization of tau and alpha-synuclein. Science (New York, N.Y.). 300: 636-40. PMID 12714745 DOI: 10.1126/Science.1082324  0.771
2003 Duda JE, Giasson BI, Lee VMY, Trojanowski JQ. Is the initial insult in Parkinson's disease and dementia with Lewy bodies a neuritic dystrophy? Annals of the New York Academy of Sciences. 991: 295-297.  0.435
2002 Giasson BI, Sampathu DM, Wilson CA, Vogelsberg-Ragaglia V, Mushynski WE, Lee VM. The environmental toxin arsenite induces tau hyperphosphorylation. Biochemistry. 41: 15376-87. PMID 12484777 DOI: 10.1021/Bi026813C  0.813
2002 Neumann M, Kahle PJ, Giasson BI, Ozmen L, Borroni E, Spooren W, Müller V, Odoy S, Fujiwara H, Hasegawa M, Iwatsubo T, Trojanowski JQ, Kretzschmar HA, Haass C. Misfolded proteinase K-resistant hyperphosphorylated alpha-synuclein in aged transgenic mice with locomotor deterioration and in human alpha-synucleinopathies. The Journal of Clinical Investigation. 110: 1429-39. PMID 12438441 DOI: 10.1172/Jci15777  0.525
2002 Duda JE, Giasson BI, Mabon ME, Lee VM, Trojanowski JQ. Novel antibodies to synuclein show abundant striatal pathology in Lewy body diseases. Annals of Neurology. 52: 205-10. PMID 12210791 DOI: 10.1002/Ana.10279  0.641
2002 Liu HN, Giasson BI, Mushynski WE, Almazan G. AMPA receptor-mediated toxicity in oligodendrocyte progenitors involves free radical generation and activation of JNK, calpain and caspase 3. Journal of Neurochemistry. 82: 398-409. PMID 12124441 DOI: 10.1046/J.1471-4159.2002.00981.X  0.636
2002 Pan ZZ, Bruening W, Giasson BI, Lee VM, Godwin AK. Gamma-synuclein promotes cancer cell survival and inhibits stress- and chemotherapy drug-induced apoptosis by modulating MAPK pathways. The Journal of Biological Chemistry. 277: 35050-60. PMID 12121974 DOI: 10.1074/Jbc.M201650200  0.476
2002 Duda JE, Giasson BI, Mabon ME, Miller DC, Golbe LI, Lee VM, Trojanowski JQ. Concurrence of alpha-synuclein and tau brain pathology in the Contursi kindred. Acta Neuropathologica. 104: 7-11. PMID 12070658 DOI: 10.1007/S00401-002-0563-3  0.673
2002 Giasson BI, Duda JE, Quinn SM, Zhang B, Trojanowski JQ, Lee VM. Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein. Neuron. 34: 521-33. PMID 12062037 DOI: 10.1016/S0896-6273(02)00682-7  0.636
2002 Giasson BI, Ischiropoulos H, Lee VM, Trojanowski JQ. The relationship between oxidative/nitrative stress and pathological inclusions in Alzheimer's and Parkinson's diseases. Free Radical Biology & Medicine. 32: 1264-75. PMID 12057764 DOI: 10.1016/S0891-5849(02)00804-3  0.618
2001 Giasson BI, Duda JE, Forman MS, Lee VM, Trojanowski JQ. Prominent perikaryal expression of alpha- and beta-synuclein in neurons of dorsal root ganglion and in medullary neurons. Experimental Neurology. 172: 354-62. PMID 11716559 DOI: 10.1006/Exnr.2001.7805  0.742
2001 Paxinou E, Chen Q, Weisse M, Giasson BI, Norris EH, Rueter SM, Trojanowski JQ, Lee VM, Ischiropoulos H. Induction of alpha-synuclein aggregation by intracellular nitrative insult. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 8053-61. PMID 11588178  0.748
2001 Giasson BI, Lee VM. Parkin and the molecular pathways of Parkinson's disease. Neuron. 31: 885-8. PMID 11580890 DOI: 10.1016/S0896-6273(01)00439-1  0.399
2001 Schmidt ML, Schuck T, Sheridan S, Kung MP, Kung H, Zhuang ZP, Bergeron C, Lamarche JS, Skovronsky D, Giasson BI, Lee VM, Trojanowski JQ. The fluorescent Congo red derivative, (trans, trans)-1-bromo-2,5-bis-(3-hydroxycarbonyl-4-hydroxy)styrylbenzene (BSB), labels diverse beta-pleated sheet structures in postmortem human neurodegenerative disease brains. The American Journal of Pathology. 159: 937-43. PMID 11549586 DOI: 10.1016/S0002-9440(10)61769-5  0.788
2001 Przedborski S, Chen Q, Vila M, Giasson BI, Djaldatti R, Vukosavic S, Souza JM, Jackson-Lewis V, Lee VM, Ischiropoulos H. Oxidative post-translational modifications of alpha-synuclein in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson's disease. Journal of Neurochemistry. 76: 637-40. PMID 11208927 DOI: 10.1046/J.1471-4159.2001.00174.X  0.444
2001 Giasson BI, Murray IV, Trojanowski JQ, Lee VM. A hydrophobic stretch of 12 amino acid residues in the middle of alpha-synuclein is essential for filament assembly. The Journal of Biological Chemistry. 276: 2380-6. PMID 11060312 DOI: 10.1074/Jbc.M008919200  0.765
2001 Paxinou E, Chen Q, Weisse M, Giasson BI, Norris EH, Rueter SM, Trojanowski JQ, Lee VM, Ischiropoulos H. Induction of α-Synuclein Aggregation by Intracellular Nitrative Insult The Journal of Neuroscience. 21: 8053-8061. DOI: 10.1523/Jneurosci.21-20-08053.2001  0.722
2000 Giasson BI, Lee VM. A new link between pesticides and Parkinson's disease. Nature Neuroscience. 3: 1227-8. PMID 11100135 DOI: 10.1038/81737  0.358
2000 Duda JE, Giasson BI, Chen Q, Gur TL, Hurtig HI, Stern MB, Gollomp SM, Ischiropoulos H, Lee VM, Trojanowski JQ. Widespread nitration of pathological inclusions in neurodegenerative synucleinopathies. The American Journal of Pathology. 157: 1439-45. PMID 11073803 DOI: 10.1016/S0002-9440(10)64781-5  0.584
2000 Giasson BI, Duda JE, Murray IV, Chen Q, Souza JM, Hurtig HI, Ischiropoulos H, Trojanowski JQ, Lee VM. Oxidative damage linked to neurodegeneration by selective alpha-synuclein nitration in synucleinopathy lesions. Science (New York, N.Y.). 290: 985-9. PMID 11062131 DOI: 10.1126/Science.290.5493.985  0.789
2000 Duda JE, Giasson BI, Gur TL, Montine TJ, Robertson D, Biaggioni I, Hurtig HI, Stern MB, Gollomp SM, Grossman M, Lee VM, Trojanowski JQ. Immunohistochemical and biochemical studies demonstrate a distinct profile of alpha-synuclein permutations in multiple system atrophy. Journal of Neuropathology and Experimental Neurology. 59: 830-41. PMID 11005264 DOI: 10.1093/Jnen/59.9.830  0.509
2000 Galvin JE, Giasson B, Hurtig HI, Lee VM, Trojanowski JQ. Neurodegeneration with brain iron accumulation, type 1 is characterized by alpha-, beta-, and gamma-synuclein neuropathology. The American Journal of Pathology. 157: 361-8. PMID 10934140 DOI: 10.1016/S0002-9440(10)64548-8  0.521
2000 Souza JM, Giasson BI, Lee VM, Ischiropoulos H. Chaperone-like activity of synucleins. Febs Letters. 474: 116-9. PMID 10828462 DOI: 10.1016/S0014-5793(00)01563-5  0.441
2000 Bruening W, Giasson BI, Klein-Szanto AJ, Lee VM, Trojanowski JQ, Godwin AK. Synucleins are expressed in the majority of breast and ovarian carcinomas and in preneoplastic lesions of the ovary. Cancer. 88: 2154-63. PMID 10813729 DOI: 10.1002/(Sici)1097-0142(20000501)88:9<2154::Aid-Cncr23>3.0.Co;2-9  0.437
2000 Souza JM, Giasson BI, Chen Q, Lee VM, Ischiropoulos H. Dityrosine cross-linking promotes formation of stable alpha -synuclein polymers. Implication of nitrative and oxidative stress in the pathogenesis of neurodegenerative synucleinopathies. The Journal of Biological Chemistry. 275: 18344-9. PMID 10747881 DOI: 10.1074/Jbc.M000206200  0.455
2000 Giasson BI, Jakes R, Goedert M, Duda JE, Leight S, Trojanowski JQ, Lee VM. A panel of epitope-specific antibodies detects protein domains distributed throughout human alpha-synuclein in Lewy bodies of Parkinson's disease. Journal of Neuroscience Research. 59: 528-33. PMID 10679792 DOI: 10.1002/(Sici)1097-4547(20000215)59:4<528::Aid-Jnr8>3.0.Co;2-0  0.656
2000 Ischiropoulos H, Souza JM, Giasson BI, Chen Q, Duda JE, Trojanowski JQ, Lee VM. Mechanisms of oxidative damage in neurodegenerative synucleinopathies Neurobiology of Aging. 21: 283. DOI: 10.1016/S0197-4580(00)83223-6  0.391
2000 Duda JE, Giasson BI, Chen Q, Souza JM, Murray IV, Ischiropoulos H, Lee VM, Trojanowski JQ. α-Synuclein nitration in neuropathological inclusions Neurobiology of Aging. 21: 53. DOI: 10.1016/S0197-4580(00)82915-2  0.708
2000 Galvin JE, Giasson BI, Gambetti PL, My Lee V, Trojanowski JQ. The neuropathology of neurodegeneration with brain iron accumulation, type 1 (NBIA 1) contains insoluble α-synuclean Neurobiology of Aging. 21: 65. DOI: 10.1016/S0197-4580(00)82514-2  0.431
1999 Giasson BI, Uryu K, Trojanowski JQ, Lee VM. Mutant and wild type human alpha-synucleins assemble into elongated filaments with distinct morphologies in vitro. The Journal of Biological Chemistry. 274: 7619-22. PMID 10075647 DOI: 10.1074/Jbc.274.12.7619  0.562
1999 Giasson BI, Bruening W, Durham HD, Mushynski WE. Activation of stress-activated protein kinases correlates with neurite outgrowth induced by protease inhibition in PC12 cells. Journal of Neurochemistry. 72: 1081-7. PMID 10037479 DOI: 10.1046/J.1471-4159.1999.0721081.X  0.651
1999 Bruening W, Roy J, Giasson B, Figlewicz DA, Mushynski WE, Durham HD. Up-regulation of protein chaperones preserves viability of cells expressing toxic Cu/Zn-superoxide dismutase mutants associated with amyotrophic lateral sclerosis. Journal of Neurochemistry. 72: 693-9. PMID 9930742 DOI: 10.1046/J.1471-4159.1999.0720693.X  0.684
1998 Lippa CF, Fujiwara H, Mann DM, Giasson B, Baba M, Schmidt ML, Nee LE, O'Connell B, Pollen DA, St George-Hyslop P, Ghetti B, Nochlin D, Bird TD, Cairns NJ, Lee VM, et al. Lewy bodies contain altered alpha-synuclein in brains of many familial Alzheimer's disease patients with mutations in presenilin and amyloid precursor protein genes. The American Journal of Pathology. 153: 1365-70. PMID 9811326 DOI: 10.1016/S0002-9440(10)65722-7  0.576
1998 Tu PH, Galvin JE, Baba M, Giasson B, Tomita T, Leight S, Nakajo S, Iwatsubo T, Trojanowski JQ, Lee VM. Glial cytoplasmic inclusions in white matter oligodendrocytes of multiple system atrophy brains contain insoluble alpha-synuclein. Annals of Neurology. 44: 415-22. PMID 9749615 DOI: 10.1002/Ana.410440324  0.554
1998 Giasson BI, Mushynski WE. Intermediate filament disassembly in cultured dorsal root ganglion neurons is associated with amino-terminal head domain phosphorylation of specific subunits. Journal of Neurochemistry. 70: 1869-75. PMID 9572270 DOI: 10.1046/J.1471-4159.1998.70051869.X  0.685
1998 Bruening W, Giasson B, Mushynski W, Durham HD. Activation of stress-activated MAP protein kinases up-regulates expression of transgenes driven by the cytomegalovirus immediate/early promoter Nucleic Acids Research. 26: 486-489. PMID 9421504 DOI: 10.1093/Nar/26.2.486  0.626
1997 Giasson BI, Mushynski WE. Study of proline-directed protein kinases involved in phosphorylation of the heavy neurofilament subunit. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 9466-72. PMID 9391002 DOI: 10.1523/Jneurosci.17-24-09466.1997  0.68
1997 Giasson BI, Mushynski WE. Developmentally regulated stabilization of neuronal intermediate filaments in rat cerebral cortex. Neuroscience Letters. 229: 77-80. PMID 9223595 DOI: 10.1016/S0304-3940(97)00425-4  0.67
1997 Giasson BI, Mushynski WE. Okadaic acid reversibly inhibits neurite outgrowth in embryonic dorsal root ganglion neurons. Journal of Neurobiology. 32: 193-201. PMID 9032661 DOI: 10.1002/(Sici)1097-4695(199702)32:2<193::Aid-Neu4>3.0.Co;2-3  0.654
1996 Giasson BI, Mushynski WE. Aberrant stress-induced phosphorylation of perikaryal neurofilaments. The Journal of Biological Chemistry. 271: 30404-9. PMID 8940004 DOI: 10.1074/Jbc.271.48.30404  0.683
1996 Giasson BI, Cromlish JA, Athlan ES, Mushynski WE. Activation of cyclic AMP-dependent protein kinase in okadaic acid-treated neurons potentiates neurofilament fragmentation and stimulates phosphorylation of Ser2 in the low-molecular-mass neurofilament subunit. Journal of Neurochemistry. 66: 1207-13. PMID 8769885 DOI: 10.1046/J.1471-4159.1996.66031207.X  0.651
1995 Jayaraman D, Giasson BI, Mushynski WE. Increased phosphorylation of neurofilament subunits in PC12 cells and rat dorsal root ganglion neurons treated with N-Acetyl-Leu-Leu-norleucinal. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 13: 753-8. PMID 8787865 DOI: 10.1016/0736-5748(95)00060-7  0.659
Show low-probability matches.