| Year |
Citation |
Score |
| 2022 |
Fang J, Zhang Y, Gerencser AA, Brand MD. Effects of sugars, fatty acids and amino acids on cytosolic and mitochondrial hydrogen peroxide release from liver cells. Free Radical Biology & Medicine. 188: 92-102. PMID 35716827 DOI: 10.1016/j.freeradbiomed.2022.06.225 |
0.342 |
|
| 2020 |
Fang J, Wong HS, Brand MD. Production of superoxide and hydrogen peroxide in the mitochondrial matrix is dominated by site I of complex I in diverse cell lines. Redox Biology. 37: 101722. PMID 32971363 DOI: 10.1016/J.Redox.2020.101722 |
0.414 |
|
| 2019 |
Goncalves RLS, Watson MA, Wong HS, Orr AL, Brand MD. The use of site-specific suppressors to measure the relative contributions of different mitochondrial sites to skeletal muscle superoxide and hydrogen peroxide production. Redox Biology. 28: 101341. PMID 31627168 DOI: 10.1016/J.Redox.2019.101341 |
0.367 |
|
| 2019 |
Wong HS, Monternier PA, Brand MD. S1QELs suppress mitochondrial superoxide/hydrogen peroxide production from site I without inhibiting reverse electron flow through Complex I. Free Radical Biology & Medicine. PMID 31518685 DOI: 10.1016/J.Freeradbiomed.2019.09.006 |
0.348 |
|
| 2019 |
Watson MA, Wong HS, Brand MD. Use of S1QELs and S3QELs to link mitochondrial sites of superoxide and hydrogen peroxide generation to physiological and pathological outcomes. Biochemical Society Transactions. PMID 31506330 DOI: 10.1042/Bst20190305 |
0.456 |
|
| 2019 |
Handel ME, Brand MD, Mookerjee SA. The Whys and Hows of Calculating Total Cellular ATP Production Rate. Trends in Endocrinology and Metabolism: Tem. PMID 31147164 DOI: 10.1016/J.Tem.2019.04.007 |
0.357 |
|
| 2019 |
Morris ME, Fang D, Heslop KA, Christie CF, Gerencser AA, Brand MD, Maldonado EN. Mitochondrial Membrane Potential Heterogeneity in Cancer Cells is Independent of the Cell Cycle and Influences Response to Hyperpolarizing Agents Biophysical Journal. 116: 272a. DOI: 10.1016/J.Bpj.2018.11.1471 |
0.367 |
|
| 2018 |
Wong HS, Benoit B, Brand MD. Mitochondrial and cytosolic sources of hydrogen peroxide in resting C2C12 myoblasts. Free Radical Biology & Medicine. PMID 30389498 DOI: 10.1016/J.Freeradbiomed.2018.10.448 |
0.453 |
|
| 2018 |
Mookerjee SA, Quinlan CL, Wong HS, Dighe P, Brand MD. Plate-Based Measurement of Respiration by Isolated Mitochondria. Methods in Molecular Biology (Clifton, N.J.). 1782: 301-313. PMID 29851007 DOI: 10.1007/978-1-4939-7831-1_17 |
0.344 |
|
| 2018 |
Wong HS, Monternier PA, Orr AL, Brand MD. Plate-Based Measurement of Superoxide and Hydrogen Peroxide Production by Isolated Mitochondria. Methods in Molecular Biology (Clifton, N.J.). 1782: 287-299. PMID 29851006 DOI: 10.1007/978-1-4939-7831-1_16 |
0.362 |
|
| 2018 |
Affourtit C, Wong HS, Brand MD. Measurement of Proton Leak in Isolated Mitochondria. Methods in Molecular Biology (Clifton, N.J.). 1782: 157-170. PMID 29850999 DOI: 10.1007/978-1-4939-7831-1_9 |
0.423 |
|
| 2018 |
Lerner C, Zhang Y, Brand MD, Gerencser AA. Development of a Kit to Measure Absolute Millivolts of Mitochondrial and Plasma Membrane Potentials in Cell Cultures Biochimica Et Biophysica Acta (Bba) - Bioenergetics. 1859: e65. DOI: 10.1016/J.Bbabio.2018.09.193 |
0.375 |
|
| 2017 |
Bunik VI, Brand MD. Generation of superoxide and hydrogen peroxide by side reactions of mitochondrial 2-oxoacid dehydrogenase complexes in isolation and in cells. Biological Chemistry. PMID 29337692 DOI: 10.1515/Hsz-2017-0284 |
0.425 |
|
| 2017 |
Wiens L, Banh S, Sotiri E, Jastroch M, Block BA, Brand MD, Treberg JR. Comparison of Mitochondrial Reactive Oxygen Species Production of Ectothermic and Endothermic Fish Muscle. Frontiers in Physiology. 8: 704. PMID 28966595 DOI: 10.3389/Fphys.2017.00704 |
0.415 |
|
| 2017 |
Wong HS, Dighe PA, Mezera V, Monternier PA, Brand MD. Production of superoxide and hydrogen peroxide from specific mitochondrial sites under different bioenergetic conditions. The Journal of Biological Chemistry. PMID 28842493 DOI: 10.1074/Jbc.R117.789271 |
0.444 |
|
| 2017 |
Mookerjee SA, Gerencser AA, Nicholls DG, Brand MD. Quantifying Intracellular Rates of Glycolytic and Oxidative ATP Production and Consumption Using Extracellular Flux Measurements. The Journal of Biological Chemistry. PMID 28270511 DOI: 10.1074/Jbc.M116.774471 |
0.318 |
|
| 2017 |
Mezera V, Gerencser AA, Brand MD. Tunicamycin Exposure Triggers Apopotosis by Superoxide Formation from Site III Qo of Mitochondrial Complex III Free Radical Biology and Medicine. 112: 172. DOI: 10.1016/J.Freeradbiomed.2017.10.268 |
0.367 |
|
| 2016 |
Gerencser AA, Mookerjee SA, Jastroch M, Brand MD. Positive Feedback Amplifies the Response of Mitochondrial Membrane Potential to Glucose Concentration in Clonal Pancreatic Beta Cells. Biochimica Et Biophysica Acta. PMID 27771512 DOI: 10.1016/J.Bbadis.2016.10.015 |
0.347 |
|
| 2016 |
Brand MD, Goncalves RL, Orr AL, Vargas L, Gerencser AA, Borch Jensen M, Wang YT, Melov S, Turk CN, Matzen JT, Dardov VJ, Petrassi HM, Meeusen SL, Perevoshchikova IV, Jasper H, et al. Suppressors of Superoxide-H2O2 Production at Site IQ of Mitochondrial Complex I Protect against Stem Cell Hyperplasia and Ischemia-Reperfusion Injury. Cell Metabolism. PMID 27667666 DOI: 10.1016/J.Cmet.2016.08.012 |
0.405 |
|
| 2016 |
Boominathan A, Vanhoozer S, Basisty N, Powers K, Crampton AL, Wang X, Friedricks N, Schilling B, Brand MD, O'Connor MS. Stable nuclear expression of ATP8 and ATP6 genes rescues a mtDNA Complex V null mutant. Nucleic Acids Research. PMID 27596602 DOI: 10.1093/nar/gkw756 |
0.32 |
|
| 2016 |
Gerencser AA, Mookerjee SA, Jastroch M, Brand MD. Measurement of the Absolute Magnitude and Time Courses of Mitochondrial Membrane Potential in Primary and Clonal Pancreatic Beta-Cells. Plos One. 11: e0159199. PMID 27404273 DOI: 10.1371/Journal.Pone.0159199 |
0.33 |
|
| 2016 |
Brand MD. Mitochondrial generation of superoxide and hydrogen peroxide as the source of mitochondrial redox signaling. Free Radical Biology & Medicine. PMID 27085844 DOI: 10.1016/J.Freeradbiomed.2016.04.001 |
0.424 |
|
| 2016 |
Gerencser AA, Brand MD. Exploiting Mitochondria In Vivo as Chemical Reaction Chambers Dependent on Membrane Potential. Molecular Cell. 61: 642-3. PMID 26942666 DOI: 10.1016/J.Molcel.2016.02.026 |
0.381 |
|
| 2016 |
Goncalves RL, Bunik VI, Brand MD. Production of superoxide/hydrogen peroxide by the mitochondrial 2-oxoadipate dehydrogenase complex. Free Radical Biology & Medicine. 91: 247-55. PMID 26708453 DOI: 10.1016/J.Freeradbiomed.2015.12.020 |
0.438 |
|
| 2016 |
Christina Y, Frazier K, Rothschild D, Mookerjee S, Brand M, Scott G, Benz CC. Abstract 215: Metabolic and mitochondrial consequences of p53 upregulation and their relation to cell fate outcomes Cancer Research. 76: 215-215. DOI: 10.1158/1538-7445.Am2016-215 |
0.321 |
|
| 2016 |
Brand MD, Wong HS. Functional Characterization of S1QELs Free Radical Biology and Medicine. 100: S31-S32. DOI: 10.1016/J.Freeradbiomed.2016.10.080 |
0.391 |
|
| 2016 |
Goncalves RLS, Bunik VI, Brand MD. Production of superoxide/hydrogen peroxide by the mitochondrial 2-oxoadipate dehydrogenase complex Free Radical Biology and Medicine. 91: 247-255. DOI: 10.1016/j.freeradbiomed.2015.12.020 |
0.301 |
|
| 2015 |
Mookerjee SA, Brand MD. Measurement and Analysis of Extracellular Acid Production to Determine Glycolytic Rate. Journal of Visualized Experiments : Jove. e53464. PMID 26709455 DOI: 10.3791/53464 |
0.341 |
|
| 2015 |
Bunik VI, Artiukhov A, Kazantsev A, Goncalves R, Daloso D, Oppermann H, Kulakovskaya E, Lukashev N, Fernie A, Brand M, Gaunitz F. Specific inhibition by synthetic analogs of pyruvate reveals that the pyruvate dehydrogenase reaction is essential for metabolism and viability of glioblastoma cells. Oncotarget. PMID 26503465 DOI: 10.18632/Oncotarget.5486 |
0.361 |
|
| 2015 |
Orr AL, Vargas L, Turk CN, Baaten JE, Matzen JT, Dardov VJ, Attle SJ, Li J, Quackenbush DC, Goncalves RL, Perevoshchikova IV, Petrassi HM, Meeusen SL, Ainscow EK, Brand MD. Suppressors of superoxide production from mitochondrial complex III. Nature Chemical Biology. 11: 834-6. PMID 26368590 DOI: 10.1038/Nchembio.1910 |
0.412 |
|
| 2015 |
Pathak D, Shields L, Mendelsohn BA, Haddad D, Lin W, Gerencser AA, Kim H, Brand MD, Edwards RH, Nakamura K. The Role of Mitochondrially Derived ATP in Synaptic Vesicle Recycling. The Journal of Biological Chemistry. PMID 26126824 DOI: 10.1074/Jbc.M115.656405 |
0.401 |
|
| 2015 |
Anderson CM, Kazantzis M, Wang J, Venkatraman S, Goncalves RL, Quinlan CL, Ng R, Jastroch M, Benjamin DI, Nie B, Herber C, Van AA, Park MJ, Yun D, Chan K, ... ... Brand MD, et al. Dependence of brown adipose tissue function on CD36-mediated coenzyme Q uptake. Cell Reports. 10: 505-15. PMID 25620701 DOI: 10.1016/J.Celrep.2014.12.048 |
0.387 |
|
| 2015 |
Mookerjee SA, Goncalves RL, Gerencser AA, Nicholls DG, Brand MD. The contributions of respiration and glycolysis to extracellular acid production. Biochimica Et Biophysica Acta. 1847: 171-81. PMID 25449966 DOI: 10.1016/J.Bbabio.2014.10.005 |
0.328 |
|
| 2015 |
Goncalves RL, Quinlan CL, Perevoshchikova IV, Hey-Mogensen M, Brand MD. Sites of superoxide and hydrogen peroxide production by muscle mitochondria assessed ex vivo under conditions mimicking rest and exercise. The Journal of Biological Chemistry. 290: 209-27. PMID 25389297 DOI: 10.1074/Jbc.M114.619072 |
0.38 |
|
| 2015 |
Nicholls DG, Brand MD, Gerencser AA. Mitochondrial bioenergetics and neuronal survival modelled in primary neuronal culture and isolated nerve terminals. Journal of Bioenergetics and Biomembranes. 47: 63-74. PMID 25172197 DOI: 10.1007/S10863-014-9573-9 |
0.353 |
|
| 2014 |
Goncalves RL, Rothschild DE, Quinlan CL, Scott GK, Benz CC, Brand MD. Sources of superoxide/H2O2 during mitochondrial proline oxidation. Redox Biology. 2: 901-9. PMID 25184115 DOI: 10.1016/J.Redox.2014.07.003 |
0.455 |
|
| 2014 |
Hey-Mogensen M, Goncalves RL, Orr AL, Brand MD. Production of superoxide/H2O2 by dihydroorotate dehydrogenase in rat skeletal muscle mitochondria. Free Radical Biology & Medicine. 72: 149-55. PMID 24746616 DOI: 10.1016/J.Freeradbiomed.2014.04.007 |
0.376 |
|
| 2014 |
Orr AL, Ashok D, Sarantos MR, Ng R, Shi T, Gerencser AA, Hughes RE, Brand MD. Novel inhibitors of mitochondrial sn-glycerol 3-phosphate dehydrogenase. Plos One. 9: e89938. PMID 24587137 DOI: 10.1371/Journal.Pone.0089938 |
0.637 |
|
| 2014 |
Quinlan CL, Goncalves RL, Hey-Mogensen M, Yadava N, Bunik VI, Brand MD. The 2-oxoacid dehydrogenase complexes in mitochondria can produce superoxide/hydrogen peroxide at much higher rates than complex I. The Journal of Biological Chemistry. 289: 8312-25. PMID 24515115 DOI: 10.1074/Jbc.M113.545301 |
0.384 |
|
| 2014 |
Goncalves RLS, Quinlan CL, Perevoshchikova IV, Hey-Mogensen M, Brand MD. Novel Insights into Mitochondrial Superoxide/H2O2 Production Rates in Vivo Free Radical Biology and Medicine. 76: S110-S111. DOI: 10.1016/J.Freeradbiomed.2014.10.232 |
0.439 |
|
| 2014 |
Brand MD, Quinlan CL, Goncalves RL, Perevoshchikova IV, Treberg JR, Hey-Mogensen M, Gerencser AA, Orr AL. Characterization and suppression of mitochondrial production of superoxide and hydrogen peroxide under near-physiological conditions Biochimica Et Biophysica Acta (Bba) - Bioenergetics. 1837: e57. DOI: 10.1016/J.Bbabio.2014.05.224 |
0.408 |
|
| 2013 |
Quinlan CL, Perevoshchikova IV, Hey-Mogensen M, Orr AL, Brand MD. Sites of reactive oxygen species generation by mitochondria oxidizing different substrates. Redox Biology. 1: 304-12. PMID 24024165 DOI: 10.1016/J.Redox.2013.04.005 |
0.355 |
|
| 2013 |
Orr AL, Ashok D, Sarantos MR, Shi T, Hughes RE, Brand MD. Inhibitors of ROS production by the ubiquinone-binding site of mitochondrial complex I identified by chemical screening. Free Radical Biology & Medicine. 65: 1047-59. PMID 23994103 DOI: 10.1016/J.Freeradbiomed.2013.08.170 |
0.64 |
|
| 2013 |
Barlow J, Hirschberg V, Brand MD, Affourtit C. Measuring mitochondrial uncoupling protein-2 level and activity in insulinoma cells. Methods in Enzymology. 528: 257-67. PMID 23849870 DOI: 10.1016/B978-0-12-405881-1.00015-X |
0.43 |
|
| 2013 |
Quinlan CL, Perevoschikova IV, Goncalves RL, Hey-Mogensen M, Brand MD. The determination and analysis of site-specific rates of mitochondrial reactive oxygen species production. Methods in Enzymology. 526: 189-217. PMID 23791102 DOI: 10.1016/B978-0-12-405883-5.00012-0 |
0.465 |
|
| 2013 |
Brand MD, Orr AL, Perevoshchikova IV, Quinlan CL. The role of mitochondrial function and cellular bioenergetics in ageing and disease. The British Journal of Dermatology. 169: 1-8. PMID 23786614 DOI: 10.1111/Bjd.12208 |
0.46 |
|
| 2013 |
McQuaker SJ, Quinlan CL, Caldwell ST, Brand MD, Hartley RC. A prototypical small-molecule modulator uncouples mitochondria in response to endogenous hydrogen peroxide production. Chembiochem : a European Journal of Chemical Biology. 14: 993-1000. PMID 23640856 DOI: 10.1002/Cbic.201300115 |
0.461 |
|
| 2013 |
Perevoshchikova IV, Quinlan CL, Orr AL, Gerencser AA, Brand MD. Sites of superoxide and hydrogen peroxide production during fatty acid oxidation in rat skeletal muscle mitochondria. Free Radical Biology & Medicine. 61: 298-309. PMID 23583329 DOI: 10.1016/J.Freeradbiomed.2013.04.006 |
0.349 |
|
| 2013 |
Patil YN, Marden B, Brand MD, Hand SC. Metabolic downregulation and inhibition of carbohydrate catabolism during diapause in embryos of Artemia franciscana. Physiological and Biochemical Zoology : Pbz. 86: 106-18. PMID 23303325 DOI: 10.1086/667808 |
0.413 |
|
| 2013 |
McQuaker SJ, Quinlan CL, Caldwell ST, Brand MD, Hartley RC. Cover Picture: A Prototypical Small-Molecule Modulator Uncouples Mitochondria in Response to Endogenous Hydrogen Peroxide Production (ChemBioChem 8/2013) Chembiochem. 14: 901-901. DOI: 10.1002/Cbic.201390025 |
0.311 |
|
| 2012 |
Choi SW, Gerencser AA, Ng R, Flynn JM, Melov S, Danielson SR, Gibson BW, Nicholls DG, Bredesen DE, Brand MD. No consistent bioenergetic defects in presynaptic nerve terminals isolated from mouse models of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 16775-84. PMID 23175831 DOI: 10.1523/Jneurosci.2414-12.2012 |
0.304 |
|
| 2012 |
Orr AL, Quinlan CL, Perevoshchikova IV, Brand MD. A refined analysis of superoxide production by mitochondrial sn-glycerol 3-phosphate dehydrogenase. The Journal of Biological Chemistry. 287: 42921-35. PMID 23124204 DOI: 10.1074/Jbc.M112.397828 |
0.458 |
|
| 2012 |
Smith S, Witkowski A, Moghul A, Yoshinaga Y, Nefedov M, de Jong P, Feng D, Fong L, Tu Y, Hu Y, Young SG, Pham T, Cheung C, Katzman SM, Brand MD, et al. Compromised mitochondrial fatty acid synthesis in transgenic mice results in defective protein lipoylation and energy disequilibrium. Plos One. 7: e47196. PMID 23077570 DOI: 10.1371/Journal.Pone.0047196 |
0.427 |
|
| 2012 |
Divakaruni AS, Humphrey DM, Brand MD. Fatty acids change the conformation of uncoupling protein 1 (UCP1). The Journal of Biological Chemistry. 287: 36845-53. PMID 22952235 DOI: 10.1074/Jbc.M112.381780 |
0.338 |
|
| 2012 |
Quinlan CL, Treberg JR, Perevoshchikova IV, Orr AL, Brand MD. Native rates of superoxide production from multiple sites in isolated mitochondria measured using endogenous reporters. Free Radical Biology & Medicine. 53: 1807-17. PMID 22940066 DOI: 10.1016/J.Freeradbiomed.2012.08.015 |
0.377 |
|
| 2012 |
Quinlan CL, Orr AL, Perevoshchikova IV, Treberg JR, Ackrell BA, Brand MD. Mitochondrial complex II can generate reactive oxygen species at high rates in both the forward and reverse reactions. The Journal of Biological Chemistry. 287: 27255-64. PMID 22689576 DOI: 10.1074/Jbc.M112.374629 |
0.356 |
|
| 2012 |
Gerencser AA, Chinopoulos C, Birket MJ, Jastroch M, Vitelli C, Nicholls DG, Brand MD. Quantitative measurement of mitochondrial membrane potential in cultured cells: calcium-induced de- and hyperpolarization of neuronal mitochondria. The Journal of Physiology. 590: 2845-71. PMID 22495585 DOI: 10.1113/Jphysiol.2012.228387 |
0.329 |
|
| 2012 |
Goehring I, Gerencser AA, Schmidt S, Brand MD, Mulder H, Nicholls DG. Plasma membrane potential oscillations in insulin secreting Ins-1 832/13 cells do not require glycolysis and are not initiated by fluctuations in mitochondrial bioenergetics. The Journal of Biological Chemistry. 287: 15706-17. PMID 22418435 DOI: 10.1074/Jbc.M111.314567 |
0.368 |
|
| 2012 |
Affourtit C, Quinlan CL, Brand MD. Measurement of proton leak and electron leak in isolated mitochondria. Methods in Molecular Biology (Clifton, N.J.). 810: 165-82. PMID 22057567 DOI: 10.1007/978-1-61779-382-0_11 |
0.396 |
|
| 2012 |
Quinlan CL, Perevoshchikova IV, Orr AL, Hey-Morgensen M, Brand MD. Native Rates of Mitochondrial Superoxide Production: A Novel Method Utilizing Endogenous Reporters Free Radical Biology and Medicine. 53: S27. DOI: 10.1016/J.Freeradbiomed.2012.10.069 |
0.424 |
|
| 2012 |
Brand M, Quinlan C, Perevoshchikova I, Orr A, Hey-Mogensen M, Treberg J. Mitochondrial superoxide production under native conditions Biochimica Et Biophysica Acta (Bba) - Bioenergetics. 1817: S96. DOI: 10.1016/J.Bbabio.2012.06.260 |
0.425 |
|
| 2011 |
Mookerjee SA, Brand MD. Characteristics of the turnover of uncoupling protein 3 by the ubiquitin proteasome system in isolated mitochondria. Biochimica Et Biophysica Acta. 1807: 1474-81. PMID 21820402 DOI: 10.1016/J.Bbabio.2011.07.011 |
0.435 |
|
| 2011 |
Rogers GW, Brand MD, Petrosyan S, Ashok D, Elorza AA, Ferrick DA, Murphy AN. High throughput microplate respiratory measurements using minimal quantities of isolated mitochondria. Plos One. 6: e21746. PMID 21799747 DOI: 10.1371/Journal.Pone.0021746 |
0.448 |
|
| 2011 |
Rodriguez KA, Wywial E, Perez VI, Lambert AJ, Edrey YH, Lewis KN, Grimes K, Lindsey ML, Brand MD, Buffenstein R. Walking the oxidative stress tightrope: a perspective from the naked mole-rat, the longest-living rodent. Current Pharmaceutical Design. 17: 2290-307. PMID 21736541 DOI: 10.2174/138161211797052457 |
0.315 |
|
| 2011 |
Brand MD, Nicholls DG. Assessing mitochondrial dysfunction in cells. The Biochemical Journal. 435: 297-312. PMID 21726199 DOI: 10.1042/Bj20110162 |
0.463 |
|
| 2011 |
Quinlan CL, Gerencser AA, Treberg JR, Brand MD. The mechanism of superoxide production by the antimycin-inhibited mitochondrial Q-cycle. The Journal of Biological Chemistry. 286: 31361-72. PMID 21708945 DOI: 10.1074/Jbc.M111.267898 |
0.326 |
|
| 2011 |
Divakaruni AS, Brand MD. The regulation and physiology of mitochondrial proton leak. Physiology (Bethesda, Md.). 26: 192-205. PMID 21670165 DOI: 10.1152/Physiol.00046.2010 |
0.381 |
|
| 2011 |
Treberg JR, Quinlan CL, Brand MD. Evidence for two sites of superoxide production by mitochondrial NADH-ubiquinone oxidoreductase (complex I). The Journal of Biological Chemistry. 286: 27103-10. PMID 21659507 DOI: 10.1074/Jbc.M111.252502 |
0.377 |
|
| 2011 |
Treberg JR, Brand MD. A model of the proton translocation mechanism of complex I. The Journal of Biological Chemistry. 286: 17579-84. PMID 21454533 DOI: 10.1074/Jbc.M111.227751 |
0.335 |
|
| 2011 |
Choi SW, Gerencser AA, Lee DW, Rajagopalan S, Nicholls DG, Andersen JK, Brand MD. Intrinsic bioenergetic properties and stress sensitivity of dopaminergic synaptosomes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 4524-34. PMID 21430153 DOI: 10.1523/Jneurosci.5817-10.2011 |
0.366 |
|
| 2011 |
Birket MJ, Orr AL, Gerencser AA, Madden DT, Vitelli C, Swistowski A, Brand MD, Zeng X. A reduction in ATP demand and mitochondrial activity with neural differentiation of human embryonic stem cells. Journal of Cell Science. 124: 348-58. PMID 21242311 DOI: 10.1242/Jcs.072272 |
0.418 |
|
| 2011 |
Affourtit C, Jastroch M, Brand MD. Uncoupling protein-2 attenuates glucose-stimulated insulin secretion in INS-1E insulinoma cells by lowering mitochondrial reactive oxygen species. Free Radical Biology & Medicine. 50: 609-16. PMID 21172424 DOI: 10.1016/J.Freeradbiomed.2010.12.020 |
0.403 |
|
| 2011 |
Yau C, Puckett R, Gerencser AA, Brand MD, Benz CC. Abstract 3797: Wildtype p53 upregulation induces contrasting bioenergetic and metabolic responses in malignant and non-malignant mammary epithelial cells Cancer Research. 71: 3797-3797. DOI: 10.1158/1538-7445.Am2011-3797 |
0.415 |
|
| 2011 |
Quinlan CL, Orr A, Treberg JR, Perevoshchikova I, Brand MD. Mitochondrial Complex II Generates Superoxide in the Forward and Reverse Directions Free Radical Biology and Medicine. 51: S139. DOI: 10.1016/J.Freeradbiomed.2011.10.295 |
0.392 |
|
| 2011 |
Perevoshchikova IV, Quinlan CL, Orr AL, Treberg JR, Brand MD. Sites of Mitochondrial ROS Production during Long-Chain Fatty Acid Oxidation Free Radical Biology and Medicine. 51: S138. DOI: 10.1016/J.Freeradbiomed.2011.10.293 |
0.405 |
|
| 2011 |
Orr AL, Quinlan CL, Perevoshchikova IV, Brand MD. A Refined Analysis of ROS Production from Mitochondrial sn-Glycerol-3-Phosphate Dehydrogenase (mGPDH) Free Radical Biology and Medicine. 51: S137-S138. DOI: 10.1016/J.Freeradbiomed.2011.10.291 |
0.453 |
|
| 2011 |
Quinlan CL, Treberg JR, Brand MD. Mechanisms of mitochondrial free radical production and their relationship to the aging process Handbook of the Biology of Aging. 47-61. DOI: 10.1016/B978-0-12-378638-8.00003-8 |
0.348 |
|
| 2010 |
Brand MD, Parker N, Affourtit C, Mookerjee SA, Azzu V. Mitochondrial uncoupling protein 2 in pancreatic β-cells. Diabetes, Obesity & Metabolism. 12: 134-40. PMID 21029310 DOI: 10.1111/J.1463-1326.2010.01264.X |
0.352 |
|
| 2010 |
Seebacher F, Brand MD, Else PL, Guderley H, Hulbert AJ, Moyes CD. Plasticity of oxidative metabolism in variable climates: molecular mechanisms. Physiological and Biochemical Zoology : Pbz. 83: 721-32. PMID 20586603 DOI: 10.1086/649964 |
0.478 |
|
| 2010 |
Jastroch M, Divakaruni AS, Mookerjee S, Treberg JR, Brand MD. Mitochondrial proton and electron leaks. Essays in Biochemistry. 47: 53-67. PMID 20533900 DOI: 10.1042/Bse0470053 |
0.452 |
|
| 2010 |
Toime LJ, Brand MD. Uncoupling protein-3 lowers reactive oxygen species production in isolated mitochondria. Free Radical Biology & Medicine. 49: 606-11. PMID 20493945 DOI: 10.1016/J.Freeradbiomed.2010.05.010 |
0.446 |
|
| 2010 |
Treberg JR, Quinlan CL, Brand MD. Hydrogen peroxide efflux from muscle mitochondria underestimates matrix superoxide production--a correction using glutathione depletion. The Febs Journal. 277: 2766-78. PMID 20491900 DOI: 10.1111/J.1742-4658.2010.07693.X |
0.383 |
|
| 2010 |
Quin C, Robertson L, McQuaker SJ, Price NC, Brand MD, Hartley RC. Caged mitochondrial uncouplers that are released in response to hydrogen peroxide. Tetrahedron. 66: 2384-2389. PMID 20418941 DOI: 10.1016/J.Tet.2010.01.103 |
0.379 |
|
| 2010 |
Mookerjee SA, Divakaruni AS, Jastroch M, Brand MD. Mitochondrial uncoupling and lifespan. Mechanisms of Ageing and Development. 131: 463-72. PMID 20363244 DOI: 10.1016/J.Mad.2010.03.010 |
0.506 |
|
| 2010 |
Azzu V, Jastroch M, Divakaruni AS, Brand MD. The regulation and turnover of mitochondrial uncoupling proteins. Biochimica Et Biophysica Acta. 1797: 785-91. PMID 20211596 DOI: 10.1016/J.Bbabio.2010.02.035 |
0.346 |
|
| 2010 |
Azzu V, Brand MD. Degradation of an intramitochondrial protein by the cytosolic proteasome. Journal of Cell Science. 123: 578-85. PMID 20103532 DOI: 10.1242/Jcs.060004 |
0.393 |
|
| 2010 |
Brand MD. The sites and topology of mitochondrial superoxide production. Experimental Gerontology. 45: 466-72. PMID 20064600 DOI: 10.1016/J.Exger.2010.01.003 |
0.432 |
|
| 2010 |
Azzu V, Brand MD. The on-off switches of the mitochondrial uncoupling proteins. Trends in Biochemical Sciences. 35: 298-307. PMID 20006514 DOI: 10.1016/J.Tibs.2009.11.001 |
0.425 |
|
| 2010 |
Lambert AJ, Buckingham JA, Boysen HM, Brand MD. Low complex I content explains the low hydrogen peroxide production rate of heart mitochondria from the long-lived pigeon, Columba livia. Aging Cell. 9: 78-91. PMID 19968628 DOI: 10.1111/J.1474-9726.2009.00538.X |
0.403 |
|
| 2010 |
Azzu V, Mookerjee SA, Brand MD. Rapid turnover of mitochondrial uncoupling protein 3. The Biochemical Journal. 426: 13-7. PMID 19954423 DOI: 10.1042/Bj20091321 |
0.398 |
|
| 2010 |
Crichton PG, Parker N, Vidal-Puig AJ, Brand MD. Not all mitochondrial carrier proteins support permeability transition pore formation: no involvement of uncoupling protein 1. Bioscience Reports. 30: 187-92. PMID 19622065 DOI: 10.1042/Bsr20090063 |
0.443 |
|
| 2010 |
Gerencser AA, Chinopoulos C, Birket MJ, Jastroch M, Nicholls DG, Brand MD. Fluorescence measurement of absolute mitochondrial membrane potential in adherent cultured cells Biochimica Et Biophysica Acta (Bba) - Bioenergetics. 1797: 125. DOI: 10.1016/J.Bbabio.2010.04.372 |
0.339 |
|
| 2009 |
Parker N, Crichton PG, Vidal-Puig AJ, Brand MD. Uncoupling protein-1 (UCP1) contributes to the basal proton conductance of brown adipose tissue mitochondria. Journal of Bioenergetics and Biomembranes. 41: 335-42. PMID 19705265 DOI: 10.1007/S10863-009-9232-8 |
0.476 |
|
| 2009 |
Singh A, Wirtz M, Parker N, Hogan M, Strahler J, Michailidis G, Schmidt S, Vidal-Puig A, Diano S, Andrews P, Brand MD, Friedman J. Leptin-mediated changes in hepatic mitochondrial metabolism, structure, and protein levels. Proceedings of the National Academy of Sciences of the United States of America. 106: 13100-5. PMID 19622746 DOI: 10.1073/Pnas.0903723106 |
0.395 |
|
| 2009 |
Bottje W, Brand MD, Ojano-Dirain C, Lassiter K, Toyomizu M, Wing T. Mitochondrial proton leak kinetics and relationship with feed efficiency within a single genetic line of male broilers. Poultry Science. 88: 1683-93. PMID 19590084 DOI: 10.3382/Ps.2009-00100 |
0.336 |
|
| 2009 |
Parker N, Vidal-Puig AJ, Azzu V, Brand MD. Dysregulation of glucose homeostasis in nicotinamide nucleotide transhydrogenase knockout mice is independent of uncoupling protein 2. Biochimica Et Biophysica Acta. 1787: 1451-7. PMID 19539600 DOI: 10.1016/J.Bbabio.2009.06.005 |
0.339 |
|
| 2009 |
Lambert AJ, Brand MD. Reactive oxygen species production by mitochondria. Methods in Molecular Biology (Clifton, N.J.). 554: 165-81. PMID 19513674 DOI: 10.1007/978-1-59745-521-3_11 |
0.401 |
|
| 2009 |
Affourtit C, Brand MD. Measuring mitochondrial bioenergetics in INS-1E insulinoma cells. Methods in Enzymology. 457: 405-24. PMID 19426881 DOI: 10.1016/S0076-6879(09)05023-X |
0.336 |
|
| 2009 |
Humphrey DM, Toivonen JM, Giannakou M, Partridge L, Brand MD. Expression of human uncoupling protein-3 in Drosophila insulin-producing cells increases insulin-like peptide (DILP) levels and shortens lifespan. Experimental Gerontology. 44: 316-27. PMID 19385039 DOI: 10.1016/J.Exger.2009.02.001 |
0.356 |
|
| 2008 |
Azzu V, Affourtit C, Breen EP, Parker N, Brand MD. Dynamic regulation of uncoupling protein 2 content in INS-1E insulinoma cells. Biochimica Et Biophysica Acta. 1777: 1378-83. PMID 18692019 DOI: 10.1016/J.Bbabio.2008.07.001 |
0.344 |
|
| 2008 |
Lambert AJ, Buckingham JA, Brand MD. Dissociation of superoxide production by mitochondrial complex I from NAD(P)H redox state. Febs Letters. 582: 1711-4. PMID 18442479 DOI: 10.1016/J.Febslet.2008.04.030 |
0.398 |
|
| 2008 |
Affourtit C, Brand MD. On the role of uncoupling protein-2 in pancreatic beta cells. Biochimica Et Biophysica Acta. 1777: 973-9. PMID 18433713 DOI: 10.1016/J.Bbabio.2008.03.022 |
0.311 |
|
| 2008 |
Azzu V, Parker N, Brand MD. High membrane potential promotes alkenal-induced mitochondrial uncoupling and influences adenine nucleotide translocase conformation. The Biochemical Journal. 413: 323-32. PMID 18426390 DOI: 10.1042/Bj20080321 |
0.464 |
|
| 2008 |
Harper ME, Green K, Brand MD. The efficiency of cellular energy transduction and its implications for obesity. Annual Review of Nutrition. 28: 13-33. PMID 18407744 DOI: 10.1146/Annurev.Nutr.28.061807.155357 |
0.372 |
|
| 2008 |
Lambert AJ, Buckingham JA, Boysen HM, Brand MD. Diphenyleneiodonium acutely inhibits reactive oxygen species production by mitochondrial complex I during reverse, but not forward electron transport. Biochimica Et Biophysica Acta. 1777: 397-403. PMID 18395512 DOI: 10.1016/J.Bbabio.2008.03.005 |
0.383 |
|
| 2008 |
Parker N, Vidal-Puig A, Brand MD. Stimulation of mitochondrial proton conductance by hydroxynonenal requires a high membrane potential. Bioscience Reports. 28: 83-8. PMID 18384278 DOI: 10.1042/Bsr20080002 |
0.497 |
|
| 2008 |
Amo T, Yadava N, Oh R, Nicholls DG, Brand MD. Experimental assessment of bioenergetic differences caused by the common European mitochondrial DNA haplogroups H and T. Gene. 411: 69-76. PMID 18280061 DOI: 10.1016/J.Gene.2008.01.007 |
0.421 |
|
| 2008 |
Parker N, Affourtit C, Vidal-Puig A, Brand MD. Energization-dependent endogenous activation of proton conductance in skeletal muscle mitochondria. The Biochemical Journal. 412: 131-9. PMID 18251717 DOI: 10.1042/Bj20080006 |
0.437 |
|
| 2008 |
Affourtit C, Brand MD. Uncoupling protein-2 contributes significantly to high mitochondrial proton leak in INS-1E insulinoma cells and attenuates glucose-stimulated insulin secretion. The Biochemical Journal. 409: 199-204. PMID 17824844 DOI: 10.1042/Bj20070954 |
0.395 |
|
| 2008 |
Parker N, Brand MD. S3.21 Contribution of mitochondrial carrier proteins to basal proton conductance Biochimica Et Biophysica Acta (Bba) - Bioenergetics. 1777: S29-S30. DOI: 10.1016/J.Bbabio.2008.05.120 |
0.421 |
|
| 2008 |
Crichton PG, Parker N, Brand MD. S3.10 A role for uncoupling protein 1 in the formation of the mitochondrial permeability transition pore? Biochimica Et Biophysica Acta (Bba) - Bioenergetics. 1777: S27. DOI: 10.1016/J.Bbabio.2008.05.109 |
0.38 |
|
| 2007 |
Affourtit C, Crichton PG, Parker N, Brand MD. Novel uncoupling proteins. Novartis Foundation Symposium. 287: 70-80; discussion 80. PMID 18074632 DOI: 10.1002/9780470725207.Ch6 |
0.405 |
|
| 2007 |
Lambert AJ, Brand MD. Research on mitochondria and aging, 2006-2007. Aging Cell. 6: 417-20. PMID 17635416 DOI: 10.1111/J.1474-9726.2007.00316.X |
0.412 |
|
| 2007 |
Ocloo A, Shabalina IG, Nedergaard J, Brand MD. Cold-induced alterations of phospholipid fatty acyl composition in brown adipose tissue mitochondria are independent of uncoupling protein-1. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 293: R1086-93. PMID 17609311 DOI: 10.1152/Ajpregu.00128.2007 |
0.33 |
|
| 2007 |
Lou PH, Hansen BS, Olsen PH, Tullin S, Murphy MP, Brand MD. Mitochondrial uncouplers with an extraordinary dynamic range. The Biochemical Journal. 407: 129-40. PMID 17608618 DOI: 10.1042/Bj20070606 |
0.439 |
|
| 2007 |
Lambert AJ, Boysen HM, Buckingham JA, Yang T, Podlutsky A, Austad SN, Kunz TH, Buffenstein R, Brand MD. Low rates of hydrogen peroxide production by isolated heart mitochondria associate with long maximum lifespan in vertebrate homeotherms. Aging Cell. 6: 607-18. PMID 17596208 DOI: 10.1111/J.1474-9726.2007.00312.X |
0.366 |
|
| 2007 |
Jastroch M, Buckingham JA, Helwig M, Klingenspor M, Brand MD. Functional characterisation of UCP1 in the common carp: uncoupling activity in liver mitochondria and cold-induced expression in the brain. Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology. 177: 743-52. PMID 17576568 DOI: 10.1007/S00360-007-0171-6 |
0.375 |
|
| 2007 |
Amo T, Brand MD. Were inefficient mitochondrial haplogroups selected during migrations of modern humans? A test using modular kinetic analysis of coupling in mitochondria from cybrid cell lines. The Biochemical Journal. 404: 345-51. PMID 17355224 DOI: 10.1042/Bj20061609 |
0.412 |
|
| 2007 |
Echtay KS, Brand MD. 4-hydroxy-2-nonenal and uncoupling proteins: an approach for regulation of mitochondrial ROS production. Redox Report : Communications in Free Radical Research. 12: 26-9. PMID 17263904 DOI: 10.1179/135100007X162158 |
0.459 |
|
| 2007 |
Brand M. Mitochondrial ROS production Comparative Biochemistry and Physiology Part a: Molecular & Integrative Physiology. 146: S56-S57. DOI: 10.1016/J.Cbpa.2007.01.044 |
0.442 |
|
| 2006 |
Blaikie FH, Brown SE, Samuelsson LM, Brand MD, Smith RA, Murphy MP. Targeting dinitrophenol to mitochondria: limitations to the development of a self-limiting mitochondrial protonophore. Bioscience Reports. 26: 231-43. PMID 16850251 DOI: 10.1007/S10540-006-9018-8 |
0.5 |
|
| 2006 |
Magwere T, Pamplona R, Miwa S, Martinez-Diaz P, Portero-Otin M, Brand MD, Partridge L. Flight activity, mortality rates, and lipoxidative damage in Drosophila Journals of Gerontology - Series a Biological Sciences and Medical Sciences. 61: 136-145. PMID 16510857 DOI: 10.1093/Gerona/61.2.136 |
0.322 |
|
| 2006 |
Magwere T, Goodall S, Skepper J, Mair W, Brand MD, Partridge L. The effect of dietary restriction on mitochondrial protein density and flight muscle mitochondrial morphology in Drosophila Journals of Gerontology - Series a Biological Sciences and Medical Sciences. 61: 36-47. PMID 16456193 DOI: 10.1093/Gerona/61.1.36 |
0.466 |
|
| 2006 |
Esteves TC, Parker N, Brand MD. Synergy of fatty acid and reactive alkenal activation of proton conductance through uncoupling protein 1 in mitochondria. The Biochemical Journal. 395: 619-28. PMID 16451125 DOI: 10.1042/Bj20052004 |
0.362 |
|
| 2006 |
Brand MD. The efficiency and plasticity of mitochondrial energy transduction. Biochemical Society Transactions. 33: 897-904. PMID 16246006 DOI: 10.1042/Bst0330897 |
0.449 |
|
| 2006 |
Affourtit C, Brand MD. Stronger control of ATP/ADP by proton leak in pancreatic beta-cells than skeletal muscle mitochondria. The Biochemical Journal. 393: 151-9. PMID 16137248 DOI: 10.1042/Bj20051280 |
0.398 |
|
| 2005 |
Echtay KS, Pakay JL, Esteves TC, Brand MD. Hydroxynonenal and uncoupling proteins: a model for protection against oxidative damage. Biofactors (Oxford, England). 24: 119-30. PMID 16403971 DOI: 10.1002/Biof.5520240114 |
0.451 |
|
| 2005 |
Miwa S, Brand MD. The topology of superoxide production by complex III and glycerol 3-phosphate dehydrogenase in Drosophila mitochondria. Biochimica Et Biophysica Acta. 1709: 214-9. PMID 16140258 DOI: 10.1016/J.Bbabio.2005.08.003 |
0.372 |
|
| 2005 |
Brand MD, Esteves TC. Physiological functions of the mitochondrial uncoupling proteins UCP2 and UCP3. Cell Metabolism. 2: 85-93. PMID 16098826 DOI: 10.1016/J.Cmet.2005.06.002 |
0.408 |
|
| 2005 |
Talbot DA, Brand MD. Uncoupling protein 3 protects aconitase against inactivation in isolated skeletal muscle mitochondria. Biochimica Et Biophysica Acta. 1709: 150-6. PMID 16084485 DOI: 10.1016/J.Bbabio.2005.07.001 |
0.465 |
|
| 2005 |
Brand MD, Pakay JL, Ocloo A, Kokoszka J, Wallace DC, Brookes PS, Cornwall EJ. The basal proton conductance of mitochondria depends on adenine nucleotide translocase content. The Biochemical Journal. 392: 353-62. PMID 16076285 DOI: 10.1042/Bj20050890 |
0.435 |
|
| 2005 |
Esteves TC, Brand MD. The reactions catalysed by the mitochondrial uncoupling proteins UCP2 and UCP3. Biochimica Et Biophysica Acta. 1709: 35-44. PMID 16005426 DOI: 10.1016/J.Bbabio.2005.06.002 |
0.462 |
|
| 2005 |
Lelliott CJ, López M, Curtis RK, Parker N, Laudes M, Yeo G, Jimenez-Liñan M, Grosse J, Saha AK, Wiggins D, Hauton D, Brand MD, O'Rahilly S, Griffin JL, Gibbons GF, et al. Transcript and metabolite analysis of the effects of tamoxifen in rat liver reveals inhibition of fatty acid synthesis in the presence of hepatic steatosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 1108-19. PMID 15985534 DOI: 10.1096/Fj.04-3196Com |
0.329 |
|
| 2004 |
Brand MD, Buckingham JA, Esteves TC, Green K, Lambert AJ, Miwa S, Murphy MP, Pakay JL, Talbot DA, Echtay KS. Mitochondrial superoxide and aging: uncoupling-protein activity and superoxide production. Biochemical Society Symposium. 203-13. PMID 15777023 DOI: 10.1042/Bss0710203 |
0.431 |
|
| 2004 |
Brand MD, Affourtit C, Esteves TC, Green K, Lambert AJ, Miwa S, Pakay JL, Parker N. Mitochondrial superoxide: production, biological effects, and activation of uncoupling proteins. Free Radical Biology & Medicine. 37: 755-67. PMID 15304252 DOI: 10.1016/J.Freeradbiomed.2004.05.034 |
0.478 |
|
| 2004 |
Lambert AJ, Brand MD. Inhibitors of the quinone-binding site allow rapid superoxide production from mitochondrial NADH:ubiquinone oxidoreductase (complex I). The Journal of Biological Chemistry. 279: 39414-20. PMID 15262965 DOI: 10.1074/Jbc.M406576200 |
0.388 |
|
| 2004 |
Miwa S, Riyahi K, Partridge L, Brand MD. Lack of correlation between mitochondrial reactive oxygen species production and life span in Drosophila Annals of the New York Academy of Sciences. 1019: 388-391. PMID 15247051 DOI: 10.1196/Annals.1297.069 |
0.433 |
|
| 2004 |
Lambert AJ, Brand MD. Superoxide production by NADH:ubiquinone oxidoreductase (complex I) depends on the pH gradient across the mitochondrial inner membrane. The Biochemical Journal. 382: 511-7. PMID 15175007 DOI: 10.1042/Bj20040485 |
0.433 |
|
| 2004 |
Else PL, Brand MD, Turner N, Hulbert AJ. Respiration rate of hepatocytes varies with body mass in birds. The Journal of Experimental Biology. 207: 2305-11. PMID 15159435 DOI: 10.1242/Jeb.01017 |
0.379 |
|
| 2004 |
Speakman JR, Talbot DA, Selman C, Snart S, McLaren JS, Redman P, Krol E, Jackson DM, Johnson MS, Brand MD. Uncoupled and surviving: individual mice with high metabolism have greater mitochondrial uncoupling and live longer. Aging Cell. 3: 87-95. PMID 15153176 DOI: 10.1111/J.1474-9728.2004.00097.X |
0.329 |
|
| 2004 |
Talbot DA, Duchamp C, Rey B, Hanuise N, Rouanet JL, Sibille B, Brand MD. Uncoupling protein and ATP/ADP carrier increase mitochondrial proton conductance after cold adaptation of king penguins. The Journal of Physiology. 558: 123-35. PMID 15146050 DOI: 10.1113/Jphysiol.2004.063768 |
0.453 |
|
| 2004 |
Green K, Brand MD, Murphy MP. Prevention of mitochondrial oxidative damage as a therapeutic strategy in diabetes. Diabetes. 53: S110-8. PMID 14749275 DOI: 10.2337/Diabetes.53.2007.S110 |
0.433 |
|
| 2004 |
Jekabsons MB, Echtay KS, Arechaga I, Brand MD. Molecular properties of purified human uncoupling protein 2 refolded from bacterial inclusion bodies. Journal of Bioenergetics and Biomembranes. 35: 409-18. PMID 14740889 DOI: 10.1023/A:1027335713635 |
0.346 |
|
| 2004 |
Talbot DA, Lambert AJ, Brand MD. Production of endogenous matrix superoxide from mitochondrial complex I leads to activation of uncoupling protein 3. Febs Letters. 556: 111-5. PMID 14706836 DOI: 10.1016/S0014-5793(03)01386-3 |
0.48 |
|
| 2004 |
Esteves TC, Echtay KS, Jonassen T, Clarke CF, Brand MD. Ubiquinone is not required for proton conductance by uncoupling protein 1 in yeast mitochondria. The Biochemical Journal. 379: 309-15. PMID 14680474 DOI: 10.1042/Bj20031682 |
0.343 |
|
| 2004 |
Miwa S, Brand MD. Mitochondrial matrix reactive oxygen species production is very sensitive to mild uncoupling. Biochemical Society Transactions. 31: 1300-1. PMID 14641047 DOI: 10.1042/Bst0311300 |
0.421 |
|
| 2004 |
Brand MD, Turner N, Ocloo A, Else PL, Hulbert AJ. Proton conductance and fatty acyl composition of liver mitochondria correlates with body mass in birds. The Biochemical Journal. 376: 741-8. PMID 12943530 DOI: 10.1042/Bj20030984 |
0.395 |
|
| 2003 |
Talbot DA, Hanuise N, Rey B, Rouanet JL, Duchamp C, Brand MD. Superoxide activates a GDP-sensitive proton conductance in skeletal muscle mitochondria from king penguin (Aptenodytes patagonicus). Biochemical and Biophysical Research Communications. 312: 983-8. PMID 14651968 DOI: 10.1016/J.Bbrc.2003.11.022 |
0.36 |
|
| 2003 |
Miwa S, St-Pierre J, Partridge L, Brand MD. Superoxide and hydrogen peroxide production by Drosophila mitochondria Free Radical Biology and Medicine. 35: 938-948. PMID 14556858 DOI: 10.1016/S0891-5849(03)00464-7 |
0.401 |
|
| 2003 |
Murphy MP, Echtay KS, Blaikie FH, Asin-Cayuela J, Cocheme HM, Green K, Buckingham JA, Taylor ER, Hurrell F, Hughes G, Miwa S, Cooper CE, Svistunenko DA, Smith RA, Brand MD. Superoxide activates uncoupling proteins by generating carbon-centered radicals and initiating lipid peroxidation: studies using a mitochondria-targeted spin trap derived from alpha-phenyl-N-tert-butylnitrone. The Journal of Biological Chemistry. 278: 48534-45. PMID 12972420 DOI: 10.1074/Jbc.M308529200 |
0.311 |
|
| 2003 |
Echtay KS, Esteves TC, Pakay JL, Jekabsons MB, Lambert AJ, Portero-Otín M, Pamplona R, Vidal-Puig AJ, Wang S, Roebuck SJ, Brand MD. A signalling role for 4-hydroxy-2-nonenal in regulation of mitochondrial uncoupling. The Embo Journal. 22: 4103-10. PMID 12912909 DOI: 10.1093/Emboj/Cdg412 |
0.48 |
|
| 2003 |
Krause MM, Brand MD, Krauss S, Meisel C, Vergin H, Burmester GR, Buttgereit F. Nonsteroidal antiinflammatory drugs and a selective cyclooxygenase 2 inhibitor uncouple mitochondria in intact cells Arthritis and Rheumatism. 48: 1438-1444. PMID 12746918 DOI: 10.1002/Art.10969 |
0.444 |
|
| 2003 |
Barger JL, Brand MD, Barnes BM, Boyer BB. Tissue-specific depression of mitochondrial proton leak and substrate oxidation in hibernating arctic ground squirrels. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 284: R1306-13. PMID 12676751 DOI: 10.1152/Ajpregu.00579.2002 |
0.452 |
|
| 2003 |
Considine MJ, Goodman M, Echtay KS, Laloi M, Whelan J, Brand MD, Sweetlove LJ. Superoxide stimulates a proton leak in potato mitochondria that is related to the activity of uncoupling protein. The Journal of Biological Chemistry. 278: 22298-302. PMID 12672801 DOI: 10.1074/Jbc.M301075200 |
0.454 |
|
| 2003 |
Bach D, Pich S, Soriano FX, Vega N, Baumgartner B, Oriola J, Daugaard JR, Lloberas J, Camps M, Zierath JR, Rabasa-Lhoret R, Wallberg-Henriksson H, Laville M, Palacín M, Vidal H, ... ... Brand M, et al. Mitofusin-2 determines mitochondrial network architecture and mitochondrial metabolism. A novel regulatory mechanism altered in obesity. The Journal of Biological Chemistry. 278: 17190-7. PMID 12598526 DOI: 10.1074/Jbc.M212754200 |
0.467 |
|
| 2003 |
Brand MD, Pamplona R, Portero-Otín M, Requena JR, Roebuck SJ, Buckingham JA, Clapham JC, Cadenas S. Oxidative damage and phospholipid fatty acyl composition in skeletal muscle mitochondria from mice underexpressing or overexpressing uncoupling protein 3. The Biochemical Journal. 368: 597-603. PMID 12193161 DOI: 10.1042/Bj20021077 |
0.391 |
|
| 2002 |
Echtay KS, Murphy MP, Smith RA, Talbot DA, Brand MD. Superoxide activates mitochondrial uncoupling protein 2 from the matrix side. Studies using targeted antioxidants. The Journal of Biological Chemistry. 277: 47129-35. PMID 12372827 DOI: 10.1074/Jbc.M208262200 |
0.469 |
|
| 2002 |
St-Pierre J, Buckingham JA, Roebuck SJ, Brand MD. Topology of superoxide production from different sites in the mitochondrial electron transport chain Journal of Biological Chemistry. 277: 44784-44790. PMID 12237311 DOI: 10.1074/Jbc.M207217200 |
0.459 |
|
| 2002 |
Roussel D, Harding M, Runswick MJ, Walker JE, Brand MD. Does any yeast mitochondrial carrier have a native uncoupling protein function? Journal of Bioenergetics and Biomembranes. 34: 165-76. PMID 12171066 DOI: 10.1023/A:1016027302232 |
0.45 |
|
| 2002 |
Hulbert AJ, Else PL, Manolis SC, Brand MD. Proton leak in hepatocytes and liver mitochondria from archosaurs (crocodiles) and allometric relationships for ectotherms Journal of Comparative Physiology B-Biochemical Systemic and Environmental Physiology. 172: 387-397. PMID 12122455 DOI: 10.1007/S00360-002-0264-1 |
0.452 |
|
| 2002 |
Harper JA, Dickinson K, Brand MD. Mitochondrial uncoupling as a target for drug development for the treatment of obesity. Obesity Reviews : An Official Journal of the International Association For the Study of Obesity. 2: 255-65. PMID 12119996 DOI: 10.1046/J.1467-789X.2001.00043.X |
0.408 |
|
| 2002 |
Jekabsons MB, Echtay KS, Brand MD. Nucleotide binding to human uncoupling protein-2 refolded from bacterial inclusion bodies. The Biochemical Journal. 366: 565-71. PMID 12030845 DOI: 10.1042/Bj20020469 |
0.308 |
|
| 2002 |
Bishop T, Ocloo A, Brand MD. Structure and function of mitochondria in hepatopancreas cells from metabolically depressed snails. Physiological and Biochemical Zoology : Pbz. 75: 134-44. PMID 12024289 DOI: 10.1086/340852 |
0.476 |
|
| 2002 |
Bishop T, St-Pierre J, Brand MD. Primary causes of decreased mitochondrial oxygen consumption during metabolic depression in snail cells American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 282. PMID 11792646 DOI: 10.1152/Ajpregu.00401.2001 |
0.509 |
|
| 2002 |
Echtay KS, Roussel D, St-Plerre J, Jekabsons MB, Cadenas S, Stuart JA, Harper JA, Roebuck SJ, Morrison A, Pickering S, Clapham JC, Brand MD. Superoxide activates mitochondrial uncoupling proteins Nature. 415: 96-99. PMID 11780125 DOI: 10.1038/415096A |
0.489 |
|
| 2002 |
Harper JA, Stuart JA, Jekabsons MB, Roussel D, Brindle KM, Dickinson K, Jones RB, Brand MD. Artifactual uncoupling by uncoupling protein 3 in yeast mitochondria at the concentrations found in mouse and rat skeletal-muscle mitochondria Biochemical Journal. 361: 49-56. PMID 11743882 DOI: 10.1042/0264-6021:3610049 |
0.433 |
|
| 2001 |
Cadenas S, Echtay KS, Harper JA, Jekabsons MB, Buckingham JA, Grau E, Abuin A, Chapman H, Clapham JC, Brand MD. The basal proton conductance of skeletal muscle mitochondria from transgenic mice overexpressing or lacking uncoupling protein-3. The Journal of Biological Chemistry. 277: 2773-8. PMID 11707458 DOI: 10.1074/Jbc.M109736200 |
0.403 |
|
| 2001 |
Stuart JA, Harper JA, Brindle KM, Jekabsons MB, Brand MD. Physiological Levels of Mammalian Uncoupling Protein 2 Do Not Uncouple Yeast Mitochondria Journal of Biological Chemistry. 276: 18633-18639. PMID 11278935 DOI: 10.1074/Jbc.M011566200 |
0.452 |
|
| 2001 |
Stuart JA, Cadenas S, Jekabsons MB, Roussel D, Brand MD. Mitochondrial proton leak and the uncoupling protein 1 homologues Biochimica Et Biophysica Acta - Bioenergetics. 1504: 144-158. PMID 11239491 DOI: 10.1016/S0005-2728(00)00243-7 |
0.436 |
|
| 2001 |
Brand MD. Uncoupling to survive? The role of mitochondrial inefficiency in ageing. Experimental Gerontology. 35: 811-20. PMID 11053672 DOI: 10.1016/S0531-5565(00)00135-2 |
0.498 |
|
| 2001 |
Cadenas S, Jekabsons M, Carroll A, Porter R, Brand M. Rat muscle mitochondria treated with dowex are GDP insensitive Biochemical Society Transactions. 29: A123-A123. DOI: 10.1042/Bst029A123C |
0.308 |
|
| 2001 |
Barger J, Brand M, Barnes B, Boyer B. Relationship between uncoupling proteins and mitochondrial proton leak in multiple tissues of arctic ground squirrels Biochemical Society Transactions. 29: A121-A121. DOI: 10.1042/Bst029A121 |
0.412 |
|
| 2001 |
Harper J, Stuart J, Brindle K, Jekabsons M, Cadenas S, Clapham J, Brand M. Artefactual uncoupling following UCP3 expression in yeast mitochondria Biochemical Society Transactions. 29: A120-A120. DOI: 10.1042/Bst029A120 |
0.361 |
|
| 2001 |
Echtay KS, Brand MD. Coenzyme Q induces GDP-sensitive proton conductance in kidney mitochondria Biochemical Society Transactions. 29: 763-768. DOI: 10.1042/Bst0290763 |
0.45 |
|
| 2001 |
HARPER JA, STUART JA, JEKABSONS MB, ROUSSEL D, BRINDLE KM, DICKINSON K, JONES RB, BRAND MD. Artifactual uncoupling by uncoupling protein 3 in yeast mitochondria at the concentrations found in mouse and rat skeletal-muscle mitochondria Biochemical Journal. 361: 49-56. DOI: 10.1042/bj3610049 |
0.323 |
|
| 2001 |
STUART JA, HARPER JA, BRINDLE KM, JEKABSONS MB, BRAND MD. A mitochondrial uncoupling artifact can be caused by expression of uncoupling protein 1 in yeast Biochemical Journal. 356: 779-789. DOI: 10.1042/Bj3560779 |
0.439 |
|
| 2000 |
Clapham JC, Arch JR, Chapman H, Haynes A, Lister C, Moore GB, Piercy V, Carter SA, Lehner I, Smith SA, Beeley LJ, Godden RJ, Herrity N, Skehel M, Changani KK, ... ... Brand MD, et al. Mice overexpressing human uncoupling protein-3 in skeletal muscle are hyperphagic and lean. Nature. 406: 415-8. PMID 10935638 DOI: 10.1038/35019082 |
0.311 |
|
| 2000 |
Yu XX, Barger JL, Boyer BB, Brand MD, Pan G, Adams SH. Impact of endotoxin on UCP homolog mRNA abundance, thermoregulation, and mitochondrial proton leak kinetics. American Journal of Physiology. Endocrinology and Metabolism. 279: E433-46. PMID 10913045 DOI: 10.1152/Ajpendo.2000.279.2.E433 |
0.396 |
|
| 2000 |
St-Pierre J, Brand MD, Boutilier RG. Mitochondria as ATP consumers: cellular treason in anoxia. Proceedings of the National Academy of Sciences of the United States of America. 97: 8670-4. PMID 10890886 DOI: 10.1073/Pnas.140093597 |
0.388 |
|
| 2000 |
Kavanagh NI, Ainscow EK, Brand MD. Calcium regulation of oxidative phosphorylation in rat skeletal muscle mitochondria. Biochimica Et Biophysica Acta. 1457: 57-70. PMID 10692550 DOI: 10.1016/S0005-2728(00)00054-2 |
0.385 |
|
| 2000 |
Buttgereit F, Burmester GR, Brand MD. Therapeutically targeting lymphocyte energy metabolism by high-dose glucocorticoids. Biochemical Pharmacology. 59: 597-603. PMID 10677575 DOI: 10.1016/S0006-2952(99)00273-7 |
0.361 |
|
| 2000 |
Cadenas S, Buckingham JA, Samec S, Seydoux J, Din N, Dulloo AG, Brand MD. UCP2 and UCP3 rise in starved rat skeletal muscle but mitochondrial proton conductance is unchanged. Febs Letters. 462: 257-60. PMID 10622707 DOI: 10.1016/S0014-5793(99)01540-9 |
0.42 |
|
| 2000 |
Ainscow EK, Brand MD. Internal regulation of ATP turnover, glycolysis and oxidative phosphorylation in rat hepatocytes. European Journal of Biochemistry. 266: 737-49. PMID 10583367 DOI: 10.1046/J.1432-1327.1999.00856.X |
0.475 |
|
| 2000 |
CADENAS S, BUCKINGHAM JA, ST-PIERRE J, DICKINSON K, JONES RB, BRAND MD. AMP decreases the efficiency of skeletal-muscle mitochondria Biochemical Journal. 351: 307-311. DOI: 10.1042/Bj3510307 |
0.402 |
|
| 2000 |
CADENAS S, BRAND MD. Effects of magnesium and nucleotides on the proton conductance of rat skeletal-muscle mitochondria Biochemical Journal. 348: 209-213. DOI: 10.1042/Bj3480209 |
0.399 |
|
| 2000 |
Brand M, Boutilier R, St-Pierre J, Bishop T. Mitochondrial proton leak in metabolic depression Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology. 126: S17. DOI: 10.1016/S0305-0491(00)80034-6 |
0.38 |
|
| 1999 |
Rolfe DFS, Newman JMB, Buckingham JA, Clark MG, Brand MD. Contribution of mitochondrial proton leak to respiration rate in working skeletal muscle and liver and to SMR. American Journal of Physiology. Cell Physiology. 276: C692-C699. PMID 29591010 DOI: 10.1152/ajpcell.1999.276.3.C692 |
0.313 |
|
| 1999 |
Stuart JA, Brindle KM, Harper JA, Brand MD. Mitochondrial proton leak and the uncoupling proteins Journal of Bioenergetics and Biomembranes. 31: 517-525. PMID 10653479 DOI: 10.1023/A:1005456725549 |
0.469 |
|
| 1999 |
Ainscow EK, Brand MD. The responses of rat hepatocytes to glucagon and adrenaline. Application of quantified elasticity analysis. European Journal of Biochemistry. 265: 1043-55. PMID 10518800 DOI: 10.1046/J.1432-1327.1999.00820.X |
0.399 |
|
| 1999 |
Ainscow EK, Brand MD. Top-down control analysis of ATP turnover, glycolysis and oxidative phosphorylation in rat hepatocytes. European Journal of Biochemistry. 263: 671-85. PMID 10469130 DOI: 10.1046/J.1432-1327.1999.00534.X |
0.475 |
|
| 1999 |
Krauss S, Buttgereit F, Brand MD. Effects of the mitogen concanavalin A on pathways of thymocyte energy metabolism. Biochimica Et Biophysica Acta. 1412: 129-38. PMID 10393256 DOI: 10.1016/S0005-2728(99)00058-4 |
0.365 |
|
| 1999 |
Rolfe DF, Newman JM, Buckingham JA, Clark MG, Brand MD. Contribution of mitochondrial proton leak to respiration rate in working skeletal muscle and liver and to SMR. The American Journal of Physiology. 276: C692-9. PMID 10069997 DOI: 10.1152/Ajpcell.1999.276.3.C692 |
0.425 |
|
| 1998 |
Brookes PS, Buckingham JA, Tenreiro AM, Hulbert AJ, Brand MD. The Proton Permeability of the Inner Membrane of Liver Mitochondria from Ectothermic and Endothermic Vertebrates and from Obese Rats: Correlations with Standard Metabolic Rate and Phospholipid Fatty Acid Composition Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology. 119: 325-334. PMID 9629666 DOI: 10.1016/S0305-0491(97)00357-X |
0.402 |
|
| 1998 |
Lionetti L, Iossa S, Liverini G, Brand MD. Changes in the hepatic mitochondrial respiratory system in the transition from weaning to adulthood in rats. Archives of Biochemistry and Biophysics. 352: 240-6. PMID 9587412 DOI: 10.1006/Abbi.1998.0579 |
0.461 |
|
| 1998 |
Lombardi A, Lanni A, Moreno M, Brand MD, Goglia F. Effect of 3,5-di-iodo-L-thyronine on the mitochondrial energy-transduction apparatus. The Biochemical Journal. 521-6. PMID 9461551 DOI: 10.1042/bj3300521 |
0.343 |
|
| 1998 |
Brand MD. Top-down elasticity analysis and its application to energy metabolism in isolated mitochondria and intact cells Molecular and Cellular Biochemistry. 184: 13-20. DOI: 10.1007/978-1-4615-5653-4_2 |
0.325 |
|
| 1997 |
Brookes PS, Hulbert AJ, Brand MD. The proton permeability of liposomes made from mitochondrial inner membrane phospholipids: No effect of fatty acid composition Biochimica Et Biophysica Acta - Biomembranes. 1330: 157-164. PMID 9408168 DOI: 10.1016/S0005-2736(97)00160-0 |
0.403 |
|
| 1997 |
Buttgereit F, Krauss S, Brand MD. Methylprednisolone inhibits uptake of Ca2+ and Na+ ions into concanavalin A-stimulated thymocytes. The Biochemical Journal. 329-32. PMID 9291100 DOI: 10.1042/Bj3260329 |
0.377 |
|
| 1997 |
Rolfe DF, Brand MD. The physiological significance of mitochondrial proton leak in animal cells and tissues. Bioscience Reports. 17: 9-16. PMID 9171916 DOI: 10.1023/A:1027327015957 |
0.421 |
|
| 1997 |
Brookes PS, Rolfe DFS, Brand MD. The proton permeability of liposomes made from mitochondrial inner membrane phospholipids: Comparison with isolated mitochondria Journal of Membrane Biology. 155: 167-174. PMID 9049110 DOI: 10.1007/S002329900168 |
0.429 |
|
| 1997 |
Lionetti L, Iossa S, Brand MD, Liverini G. Relationship between membrane potential and respiration rate in isolated liver mitochondria from rats fed an energy dense diet. Molecular and Cellular Biochemistry. 158: 133-8. PMID 8817475 DOI: 10.1007/Bf00225839 |
0.396 |
|
| 1996 |
Chien LF, Brand MD. The effect of chloroform on mitochondrial energy transduction Biochemical Journal. 320: 837-845. PMID 9003370 DOI: 10.1042/Bj3200837 |
0.451 |
|
| 1996 |
Porter RK, Hulbert AJ, Brand MD. Allometry of mitochondrial proton leak: Influence of membrane surface area and fatty acid composition American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 271. PMID 8997352 DOI: 10.1152/Ajpregu.1996.271.6.R1550 |
0.344 |
|
| 1996 |
Rolfe DF, Brand MD. Contribution of mitochondrial proton leak to skeletal muscle respiration and to standard metabolic rate. The American Journal of Physiology. 271: C1380-9. PMID 8897845 DOI: 10.1152/Ajpcell.1996.271.4.C1380 |
0.39 |
|
| 1996 |
Rolfe DF, Brand MD. Proton leak and control of oxidative phosphorylation in perfused, resting rat skeletal muscle. Biochimica Et Biophysica Acta. 1276: 45-50. PMID 8764890 DOI: 10.1016/0005-2728(96)00029-1 |
0.411 |
|
| 1996 |
Borutaite V, Mildaziene V, Brown GC, Brand MD. Control and kinetic analysis of ischemia-damaged heart mitochondria: which parts of the oxidative phosphorylation system are affected by ischemia? Biochimica Et Biophysica Acta. 1272: 154-8. PMID 8541346 DOI: 10.1016/0925-4439(95)00080-1 |
0.435 |
|
| 1996 |
Buttgereit F, Brand MD. A hierarchy of ATP-consuming processes in mammalian cells. The Biochemical Journal. 163-7. PMID 7492307 DOI: 10.1042/Bj3120163 |
0.4 |
|
| 1996 |
Lionetti L, Iossa S, Brand MD, Liverini G. The mechanism of stimulation of respiration in isolated hepatocytes from rats fed an energy-dense diet The Journal of Nutritional Biochemistry. 7: 571-576. DOI: 10.1016/S0955-2863(96)00122-2 |
0.361 |
|
| 1995 |
Harper ME, Brand MD. Use of top-down elasticity analysis to identify sites of thyroid hormone-induced thermogenesis. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 208: 228-37. PMID 7878061 DOI: 10.3181/00379727-208-43852B |
0.375 |
|
| 1995 |
Harper ME, Brand MD. Hyperthyroidism stimulates mitochondrial proton leak and ATP turnover in rat hepatocytes but does not change the overall kinetics of substrate oxidation reactions. Canadian Journal of Physiology and Pharmacology. 72: 899-908. PMID 7834578 DOI: 10.1139/Y94-127 |
0.452 |
|
| 1995 |
Rolfe DF, Hulbert AJ, Brand MD. Characteristics of mitochondrial proton leak and control of oxidative phosphorylation in the major oxygen-consuming tissues of the rat. Biochimica Et Biophysica Acta. 1188: 405-16. PMID 7803454 DOI: 10.1016/0005-2728(94)90062-0 |
0.475 |
|
| 1995 |
Korzeniewski B, Harper ME, Brand MD. Proportional activation coefficients during stimulation of oxidative phosphorylation by lactate and pyruvate or by vasopressin. Biochimica Et Biophysica Acta. 1229: 315-22. PMID 7748883 DOI: 10.1016/0005-2728(95)00008-7 |
0.33 |
|
| 1995 |
Brand MD, Kesseler A. Control analysis of energy metabolism in mitochondria. Biochemical Society Transactions. 23: 371-6. PMID 7672401 DOI: 10.1042/Bst0230371 |
0.336 |
|
| 1995 |
Porter RK, Brand MD. Mitochondrial proton conductance and H+/O ratio are independent of electron transport rate in isolated hepatocytes Biochemical Journal. 310: 379-382. PMID 7654171 DOI: 10.1042/Bj3100379 |
0.477 |
|
| 1995 |
Porter RK, Brand MD. Causes of differences in respiration rate of hepatocytes from mammals of different body mass American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 269. PMID 7503313 DOI: 10.1152/Ajpregu.1995.269.5.R1213 |
0.458 |
|
| 1995 |
Ainscow EK, Brand MD. Top-down control analysis of systems with more than one common intermediate Febs Journal. 231: 579-586. DOI: 10.1111/J.1432-1033.1995.0579D.X |
0.371 |
|
| 1994 |
Brand MD, Chien LF, Diolez P. Experimental discrimination between proton leak and redox slip during mitochondrial electron transport. The Biochemical Journal. 27-9. PMID 8280106 DOI: 10.1042/Bj2970027 |
0.446 |
|
| 1994 |
Brand MD, Chien LF, Ainscow EK, Rolfe DFS, Porter RK. The causes and functions of mitochondrial proton leak Bba - Bioenergetics. 1187: 132-139. PMID 8075107 DOI: 10.1016/0005-2728(94)90099-X |
0.507 |
|
| 1994 |
Buttgereit F, Grant A, Müller M, Brand MD. The effects of methylprednisolone on oxidative phosphorylation in Concanavalin-A-stimulated thymocytes. Top-down elasticity analysis and control analysis. European Journal of Biochemistry. 223: 513-9. PMID 8055921 DOI: 10.1111/J.1432-1033.1994.Tb19020.X |
0.4 |
|
| 1994 |
Brand MD, Couture P, Hulbert AJ. Liposomes from mammalian liver mitochondria are more polyunsaturated and leakier to protons than those from reptiles. Comparative Biochemistry and Physiology. Biochemistry and Molecular Biology. 108: 181-8. PMID 8055185 DOI: 10.1016/0305-0491(94)90064-7 |
0.374 |
|
| 1994 |
Kesseler A, Brand MD. Quantitative determination of the regulation of oxidative phosphorylation by cadmium in potato tuber mitochondria. European Journal of Biochemistry. 225: 923-35. PMID 7957229 DOI: 10.1111/J.1432-1033.1994.0923B.X |
0.33 |
|
| 1994 |
Kesseler A, Brand MD. Effects of cadmium on the control and internal regulation of oxidative phosphorylation in potato tuber mitochondria. European Journal of Biochemistry. 225: 907-22. PMID 7957228 DOI: 10.1111/J.1432-1033.1994.0907B.X |
0.36 |
|
| 1994 |
Kesseler A, Brand MD. Localisation of the sites of action of cadmium on oxidative phosphorylation in potato tuber mitochondria using top-down elasticity analysis. European Journal of Biochemistry. 225: 897-906. PMID 7957227 DOI: 10.1111/J.1432-1033.1994.0897B.X |
0.328 |
|
| 1993 |
Brand MD, Harper ME, Taylor HC. Control of the effective P/O ratio of oxidative phosphorylation in liver mitochondria and hepatocytes. The Biochemical Journal. 739-48. PMID 8489502 DOI: 10.1042/Bj2910739 |
0.379 |
|
| 1993 |
Kaplan CP, Porter RK, Brand MD. The choline transporter is the major site of control of choline oxidation in isolated rat liver mitochondria Febs Letters. 321: 24-26. PMID 8467907 DOI: 10.1016/0014-5793(93)80613-Y |
0.4 |
|
| 1993 |
Porter RK, Scott JM, Brand MD. Characterization of betaine efflux from rat liver mitochondria. Biochimica Et Biophysica Acta. 1141: 269-74. PMID 8443213 DOI: 10.1016/0005-2728(93)90052-H |
0.444 |
|
| 1993 |
Quant PA, Robin D, Robin P, Girard J, Brand MD. A top-down control analysis in isolated rat liver mitochondria: can the 3-hydroxy-3-methylglutaryl-CoA pathway be rate-controlling for ketogenesis? Biochimica Et Biophysica Acta. 1156: 135-43. PMID 8427872 DOI: 10.1016/0304-4165(93)90128-U |
0.35 |
|
| 1993 |
Porter RK, Brand MD. Body mass dependence of H+ leak in mitochondria and its relevance to metabolic rate Nature. 362: 628-630. PMID 8385274 DOI: 10.1038/362628A0 |
0.382 |
|
| 1993 |
Harper ME, Ballantyne JS, Leach M, Brand MD. Effects of thyroid hormones on oxidative phosphorylation. Biochemical Society Transactions. 785-92. PMID 8224511 DOI: 10.1042/Bst0210785 |
0.341 |
|
| 1993 |
Diolez P, Kesseler A, Haraux F, Valerio M, Brinkmann K, Brand MD. Regulation of oxidative phosphorylation in plant mitochondria Biochemical Society Transactions. 21: 769-773. PMID 8224507 DOI: 10.1042/Bst0210769 |
0.311 |
|
| 1993 |
Brand MD, Chien LF, Rolfe DF. Control of oxidative phosphorylation in liver mitochondria and hepatocytes. Biochemical Society Transactions. 757-62. PMID 8224505 DOI: 10.1042/Bst0210757 |
0.346 |
|
| 1993 |
Buttgereit F, Brand MD, Müller M. Effects of methylprednisolone on the energy metabolism of quiescent and ConA-stimulated thymocytes of the rat. Bioscience Reports. 13: 41-52. PMID 7687156 DOI: 10.1007/Bf01138177 |
0.342 |
|
| 1993 |
Brand M. Bioenergetics 2 Trends in Biochemical Sciences. 18: 189. DOI: 10.1016/0968-0004(93)90113-2 |
0.423 |
|
| 1992 |
Kesseler A, Diolez P, Brinkmann K, Brand MD. Characterisation of the control of respiration in potato tuber mitochondria using the top-down approach of metabolic control analysis European Journal of Biochemistry. 210: 775-784. PMID 1483462 DOI: 10.1111/J.1432-1033.1992.Tb17480.X |
0.354 |
|
| 1992 |
Porter RK, Scott JM, Brand MD. Choline transport into rat liver mitochondria. Biochemical Society Transactions. 20: 248S. PMID 1426542 DOI: 10.1042/Bst020248S |
0.45 |
|
| 1992 |
Porter RK, Scott JM, Brand MD. The nature of betaine efflux from rat liver mitochondria Biochemical Society Transactions. 20. PMID 1426541 DOI: 10.1042/Bst020247S |
0.321 |
|
| 1992 |
Buttgereit F, Brand MD, Müller M. ConA induced changes in energy metabolism of rat thymocytes. Bioscience Reports. 12: 109-14. PMID 1384753 DOI: 10.1007/Bf02351215 |
0.41 |
|
| 1992 |
Brand MD, Steverding D, Kadenbach B, Stevenson PM, Hafner RP. The mechanism of the increase in mitochondrial proton permeability induced by thyroid hormones. European Journal of Biochemistry / Febs. 206: 775-81. PMID 1318835 DOI: 10.1111/J.1432-1033.1992.Tb16984.X |
0.434 |
|
| 1991 |
Brand MD, D'Alessandri L, Reis HM, Hafner RP. Stimulation of the electron transport chain in mitochondria isolated from rats treated with mannoheptulose or glucagon. Archives of Biochemistry and Biophysics. 283: 278-84. PMID 2177325 DOI: 10.1016/0003-9861(90)90643-D |
0.45 |
|
| 1991 |
Brand MD, Couture P, Else PL, Withers KW, Hulbert AJ. Evolution of energy metabolism. Proton permeability of the inner membrane of liver mitochondria is greater in a mammal than in a reptile. The Biochemical Journal. 81-6. PMID 1850242 DOI: 10.1042/bj2750081 |
0.38 |
|
| 1991 |
Hafner RP, Brand MD. Effect of protonmotive force on the relative proton stoichiometries of the mitochondrial proton pumps. The Biochemical Journal. 75-80. PMID 1708235 DOI: 10.1042/Bj2750075 |
0.391 |
|
| 1991 |
Quant PA, Robin D, Robin P, Ferre P, Brand MD, Girard J. Control of hepatic mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase during the foetal/neonatal transition, suckling and weaning in the rat. European Journal of Biochemistry. 195: 449-54. PMID 1671765 DOI: 10.1111/J.1432-1033.1991.Tb15724.X |
0.414 |
|
| 1991 |
Brown GC, Brand MD. On the nature of the mitochondrial proton leak. Biochimica Et Biophysica Acta. 1059: 55-62. PMID 1651764 DOI: 10.1016/S0005-2728(05)80187-2 |
0.449 |
|
| 1990 |
Brand MD. The proton leak across the mitochondrial inner membrane. Biochimica Et Biophysica Acta. 1018: 128-33. PMID 2393654 DOI: 10.1016/0005-2728(90)90232-S |
0.48 |
|
| 1990 |
Hafner RP, Brown GC, Brand MD. Thyroid-hormone control of state-3 respiration in isolated rat liver mitochondria. The Biochemical Journal. 265: 731-4. PMID 2306210 DOI: 10.1042/Bj2650731 |
0.392 |
|
| 1990 |
Brown GC, Lakin-Thomas PL, Brand MD. Control of respiration and oxidative phosphorylation in isolated rat liver cells. European Journal of Biochemistry. 192: 355-62. PMID 2209591 DOI: 10.1111/J.1432-1033.1990.Tb19234.X |
0.492 |
|
| 1990 |
Brand MD. The contribution of the leak of protons across the mitochondrial inner membrane to standard metabolic rate. Journal of Theoretical Biology. 145: 267-86. PMID 2169556 DOI: 10.1016/S0022-5193(05)80131-6 |
0.46 |
|
| 1990 |
Hafner RP, Brown GC, Brand MD. Analysis of the control of respiration rate, phosphorylation rate, proton leak rate and protonmotive force in isolated mitochondria using the 'top-down' approach of metabolic control theory. European Journal of Biochemistry. 188: 313-9. PMID 2156698 DOI: 10.1111/J.1432-1033.1990.Tb15405.X |
0.341 |
|
| 1990 |
Johnston JD, Brand MD. The mechanism of Ca2+ stimulation of citrulline and N-acetylglutamate synthesis by mitochondria Bba - General Subjects. 1033: 85-90. PMID 2105747 DOI: 10.1016/0304-4165(90)90198-6 |
0.322 |
|
| 1990 |
Quant PA, Tubbs PK, Brand MD. Glucagon activates mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase in vivo by decreasing the extent of succinylation of the enzyme. European Journal of Biochemistry. 187: 169-74. PMID 1967579 DOI: 10.1111/J.1432-1033.1990.Tb15291.X |
0.38 |
|
| 1989 |
Lakin-Thomas PL, Brand MD. Stimulation of respiration by mitogens in rat thymocytes is independent of mitochondrial calcium. The Biochemical Journal. 256: 167-73. PMID 3223899 DOI: 10.1042/Bj2560167 |
0.397 |
|
| 1989 |
Johnston JD, Brand MD. Sub-micromolar concentrations of extramitochondrial Ca2+ stimulate the rate of citrulline synthesis by rat liver mitochondria Biochemical Journal. 257: 285-288. PMID 2920019 DOI: 10.1042/Bj2570285 |
0.315 |
|
| 1989 |
Hafner RP, Nobes CD, McGown AD, Brand MD. Altered relationship between protonmotive force and respiration rate in non-phosphorylating liver mitochondria isolated from rats of different thyroid hormone status. European Journal of Biochemistry. 178: 511-8. PMID 2850181 DOI: 10.1111/J.1432-1033.1988.Tb14477.X |
0.436 |
|
| 1989 |
Quant PA, Tubbs PK, Brand MD. Treatment of rats with glucagon or mannoheptulose increases mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase activity and decreases succinyl-CoA content in liver. The Biochemical Journal. 262: 159-64. PMID 2573345 DOI: 10.1042/Bj2620159 |
0.443 |
|
| 1989 |
Hafner RP, Leake MJ, Brand MD. Hypothyroidism in rats decreases mitochondrial inner membrane cation permeability. Febs Letters. 248: 175-8. PMID 2542084 DOI: 10.1016/0014-5793(89)80455-7 |
0.425 |
|
| 1989 |
Nobes CD, Lakin-Thomas PL, Brand MD. The contribution of ATP turnover by the Na+/K+-ATPase to the rate of respiration of hepatocytes. Effects of thyroid status and fatty acids. Biochimica Et Biophysica Acta. 976: 241-5. PMID 2477065 DOI: 10.1016/S0005-2728(89)80236-1 |
0.325 |
|
| 1989 |
QUANT PA, TUBBS PK, BRAND MD. Glucagon increases mitochondrial 3-hydroxy-3-methylglutaryl-coenzyme A synthase activity in vivo by desuccinylating the enzyme Biochemical Society Transactions. 17: 147-148. DOI: 10.1042/Bst0170147 |
0.42 |
|
| 1988 |
Brown GC, Brand MD. Proton/electron stoichiometry of mitochondrial complex I estimated from the equilibrium thermodynamic force ratio Biochemical Journal. 252: 473-479. PMID 2843170 DOI: 10.1042/Bj2520473 |
0.362 |
|
| 1988 |
Murphy MP, Brand MD. The stoichiometry of charge translocation by cytochrome oxidase and the cytochrome bc1 complex of mitochondria at high membrane potential European Journal of Biochemistry. 173: 645-651. PMID 2836196 DOI: 10.1111/J.1432-1033.1988.Tb14047.X |
0.369 |
|
| 1988 |
Murphy MP, Brand MD. Membrane-potential-dependent changes in the stoichiometry of charge translocation by the mitochondrial electron transport chain European Journal of Biochemistry. 173: 637-644. PMID 2836195 DOI: 10.1111/J.1432-1033.1988.Tb14046.X |
0.41 |
|
| 1988 |
Hafner RP, Brand MD. Hypothyroidism in rats does not lower mitochondrial ADP/O and H+/O ratios. The Biochemical Journal. 250: 477-84. PMID 2833245 DOI: 10.1042/Bj2500477 |
0.368 |
|
| 1988 |
QUANT PA, TUBBS PK, BRAND MD. Mannoheptulose and glucagon treatment of fed rats stimulates 3-hydroxy-3-methylglutaryl-CoA synthase activity in rat liver mitochondria by desuccinylation of the enzyme Biochemical Society Transactions. 16: 633-634. DOI: 10.1042/Bst0160633 |
0.309 |
|
| 1987 |
Lakin-Thomas PL, Brand MD. Mitogenic stimulation transiently increases the exchangeable mitochondrial calcium pool in rat thymocytes. The Biochemical Journal. 246: 173-7. PMID 3675554 DOI: 10.1042/Bj2460173 |
0.407 |
|
| 1987 |
Johnston JD, Brand MD. Stimulation of the respiration rate of rat liver mitochondria by sub-micromolar concentrations of extramitochondrial Ca2+ Biochemical Journal. 245: 217-222. PMID 3663147 DOI: 10.1042/Bj2450217 |
0.388 |
|
| 1987 |
Brand MD, Murphy MP. Control of electron flux through the respiratory chain in mitochondria and cells Biological Reviews of the Cambridge Philosophical Society. 62: 141-193. PMID 3300795 DOI: 10.1111/J.1469-185X.1987.Tb01265.X |
0.442 |
|
| 1987 |
Murphy MP, Brand MD. Variable stoichiometry of proton pumping by the mitochondrial respiratory chain Nature. 329: 170-172. PMID 3041231 DOI: 10.1038/329170A0 |
0.439 |
|
| 1987 |
QUANT PA, TUBBS PK, BRAND MD. Stimulation of 3-hydroxy-3-methylglutaryl coenzyme A synthase activity in rat liver mitochondria isolated from glucagon-treated rats Biochemical Society Transactions. 15: 1133-1134. DOI: 10.1042/Bst0151133 |
0.318 |
|
| 1986 |
JOHNSTON JD, BRAND MD. Some properties of rat liver mitochondria with low Ca2+ content Biochemical Society Transactions. 14: 1182-1182. DOI: 10.1042/Bst0141182 |
0.352 |
|
| 1986 |
MURPHY MP, CHOJNOWSKA EI, BRAND MD. Substrate dependence of the relationship between membrane potential and respiration rate in mitochondria Biochemical Society Transactions. 14: 1042-1043. DOI: 10.1042/Bst0141042 |
0.377 |
|
| 1985 |
Brand MD, Felber SM. The intracellular calcium antagonist TMB-8 [8-(NN-diethylamino)octyl-3,4,5-trimethoxybenzoate] inhibits mitochondrial ATP production in rat thymocytes. The Biochemical Journal. 224: 1027-30. PMID 6525171 DOI: 10.1042/Bj2241027 |
0.426 |
|
| 1985 |
Hughes SM, Brand MD. Light changes the membrane potential and ion balances of retinal rod disks Febs Letters. 182: 380-384. PMID 3979560 DOI: 10.1016/0014-5793(85)80337-9 |
0.536 |
|
| 1985 |
Murphy MP, Brown GC, Brand MD. Thermodynamic limits to the stoichiometry of H+ pumping by mitochondrial cytochrome oxidase Febs Letters. 187: 16-20. PMID 2991005 DOI: 10.1016/0014-5793(85)81204-7 |
0.39 |
|
| 1985 |
Brand MD, Al-Shawi MK, Brown GC, Price BD. Thermodynamic and steady-state-kinetic investigation of the effect of NN'-dicyclohexylcarbodi-imide on H+ translocation by the mitochondrial cytochrome bc1 complex. The Biochemical Journal. 225: 407-11. PMID 2983671 DOI: 10.1042/Bj2250407 |
0.346 |
|
| 1985 |
PRICE BD, BRAND MD. Apparent variation in mitochondrial H+/2e caused by Mg2+ Biochemical Society Transactions. 13: 695-696. DOI: 10.1042/Bst0130695 |
0.369 |
|
| 1985 |
BROWN GC, BRAND MD. Respiratory control in the mitochondrial bc1 complex Biochemical Society Transactions. 13: 693-693. DOI: 10.1042/Bst0130693 |
0.412 |
|
| 1984 |
Brand MD, Felber SM. Membrane potential of mitochondria in intact lymphocytes during early mitogenic stimulation. The Biochemical Journal. 217: 453-9. PMID 6696741 DOI: 10.1042/Bj2170453 |
0.376 |
|
| 1984 |
Hughes SM, Harper G, Brand MD. Target size analysis of rhodopsin in retinal rod disk membranes Biochemical and Biophysical Research Communications. 122: 56-61. PMID 6234896 DOI: 10.1016/0006-291X(84)90438-8 |
0.531 |
|
| 1983 |
Felber SM, Brand MD. Valinomycin can depolarize mitochondria in intact lymphocytes without increasing plasma membrane potassium fluxes. Febs Letters. 150: 122-4. PMID 7160466 DOI: 10.1016/0014-5793(82)81317-3 |
0.335 |
|
| 1983 |
Price BD, Brand MD. Chemical modification of the mitochondrial bc1 complex by N,N'-dicyclohexylcarbodiimide inhibits proton translocation. European Journal of Biochemistry / Febs. 132: 595-601. PMID 6303780 DOI: 10.1111/J.1432-1033.1983.Tb07405.X |
0.387 |
|
| 1983 |
Hughes SM, Brand MD. Size changes of phosphodiesterase in bovine rod outer segments on illumination Biochemistry. 22: 1704-1708. PMID 6303392 DOI: 10.1021/bi00276a028 |
0.501 |
|
| 1983 |
HUGHES SM, BRAND MD. Rhodopsin in the disc membrane is a monomer Biochemical Society Transactions. 11: 691-692. DOI: 10.1042/Bst0110691 |
0.543 |
|
| 1981 |
Al-Shawi MK, Brand MD. THE H+/O STOICHIOMETRY OF RESPIRATION-LINKED H+ TRANSPORT IN LIVER MITOCHONDRIA Biochemical Society Transactions. 9: 198P-198P. DOI: 10.1042/Bst009198Pc |
0.312 |
|
| 1981 |
Dippenaar NG, Brand MD. RATE OF CALCIUM TRANSPORT BY RAT LIVER MITOCHONDRIA Biochemical Society Transactions. 9: 138P-138P. DOI: 10.1042/Bst009138Pd |
0.324 |
|
| 1981 |
Bardsley ME, Brand MD. CALCIUM EFFLUX FROM ISOLATED LIVER MITOCHONDRIA FOLLOWING OXIDATION OF ENDOGENOUS NUCLEOTIDES Biochemical Society Transactions. 9: 135P-135P. DOI: 10.1042/Bst009135Pc |
0.331 |
|
| 1980 |
Brand MD, De Selincourt C. Effects of glucagon and Na+ on the control of extramitochondrial free Ca2+ concentration by mitochondrial from liver and heart. Biochemical and Biophysical Research Communications. 92: 1377-82. PMID 7370042 DOI: 10.1016/0006-291X(80)90438-6 |
0.34 |
|
| 1980 |
Brand MD. Measurement of the intramitochondrial P/O ratio. Biochemical and Biophysical Research Communications. 91: 592-8. PMID 518656 DOI: 10.1016/0006-291X(79)91563-8 |
0.328 |
|
| 1979 |
Reynafarje B, Brand MD, Alexandre A, Lehninger AL. Determination of the H+/site and Ca2+/site ratios of mitochondrial electron transport. Methods in Enzymology. 55: 640-56. PMID 37405 DOI: 10.1016/0076-6879(79)55072-1 |
0.582 |
|
| 1979 |
Brand MD. A new steady-state method for investigating mitochondrial proton transport [proceedings]. Biochemical Society Transactions. 7: 221-3. PMID 35423 DOI: 10.1042/Bst0070221 |
0.401 |
|
| 1978 |
Brand MD, Harper WG, Nicholls DG, Ingledew WJ. Unequal charge separation by different coupling spans of the mitochondrial electron transport chain. Febs Letters. 95: 125-9. PMID 720593 DOI: 10.1016/0014-5793(78)80066-0 |
0.418 |
|
| 1978 |
Brand MD. The stoicheiometric relationships between electron transport, proton translocation and adenosine triphosphate synthesis and hydrolysis in mitochondria. Biochemical Society Transactions. 5: 1615-20. PMID 21825 DOI: 10.1042/Bst0051615 |
0.397 |
|
| 1977 |
Brand MD, Lehninger AL. H+/ATP ratio during ATP hydrolysis by mitochondria: modification of the chemiosmotic theory. Proceedings of the National Academy of Sciences of the United States of America. 74: 1955-9. PMID 17116 |
0.53 |
|
| 1976 |
Brand MD, Reynafarje B, Lehninger AL. Stoichiometric relationship between energy-dependent proton ejection and electron transport in mitochondria. Proceedings of the National Academy of Sciences of the United States of America. 73: 437-41. PMID 1061146 |
0.542 |
|
| 1976 |
Brand MD, Reynafarje B, Lehninger AL. The H+/site ratio of mitochondrial electron transport Journal of Cellular Physiology. 89: 595-602. PMID 1034632 DOI: 10.1002/Jcp.1040890415 |
0.531 |
|
| 1975 |
Brand MD, Chappell JB. Glutamate and aspartate transport in rat brain mitochondria. The Biochemical Journal. 140: 205-10. PMID 4375961 DOI: 10.1042/bj1400205 |
0.503 |
|
| 1974 |
Halling PJ, Brand MD, Chappell JB. Permeability of mitochondria to neutral amino acids. Febs Letters. 34: 169-71. PMID 4747839 DOI: 10.1016/0014-5793(73)80785-9 |
0.441 |
|
| 1974 |
Halestrap AP, Brand MD, Denton RM. Inhibition of mitochondrial pyruvate transport by phenylpyruvate and α-ketoisocaproate Bba - Biomembranes. 367: 102-108. PMID 4418160 DOI: 10.1016/0005-2736(74)90140-0 |
0.314 |
|
| 1974 |
Brand MD, Chappell JB. Permeability of mitochondria from rat brain and rat liver to GABA. Journal of Neurochemistry. 22: 47-51. PMID 4150473 DOI: 10.1111/j.1471-4159.1974.tb12177.x |
0.422 |
|
| 1974 |
HALESTRAP AP, BRAND MD, DENTON RM. Inhibition of Mitochondria1 Pyruvate Transport by Phenylpyruvate and α-Oxo-4-methylpentanoate Biochemical Society Transactions. 2: 980-982. DOI: 10.1042/Bst0020980 |
0.322 |
|
| 1973 |
Brand MD, Evans SM, Mendes-Mourão J, Chappell JB. Fluorocitrate inhibition of aconitate hydratase and the tricarboxylate carrier of rat liver mitochondria. The Biochemical Journal. 134: 217-24. PMID 4723224 DOI: 10.1042/bj1340217 |
0.476 |
|
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