Vladimir R. Muzykantov - Publications

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
Area:
Biomedical Engineering

255 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Nong J, Glassman PM, Myerson JW, Zuluaga-Ramirez V, Rodriguez-Garcia A, Mukalel A, Omo-Lamai S, Walsh LR, Zamora ME, Gong X, Wang Z, Bhamidipati K, Kiseleva RY, Villa CH, Greineder CF, ... ... Muzykantov VR, et al. Targeted Nanocarriers Co-Opting Pulmonary Intravascular Leukocytes for Drug Delivery to the Injured Brain. Acs Nano. PMID 37432926 DOI: 10.1021/acsnano.2c08275  0.671
2023 Nong J, Glassman PM, Reyes-Esteves S, Descamps HC, Shuvaev VV, Kiseleva RY, Papp TE, Alameh MG, Tam YK, Mui BL, Omo-Lamai S, Zamora ME, Shuvaeva T, Arguiri E, Thaiss CA, ... ... Muzykantov VR, et al. Targeting lipid nanoparticles to the blood brain barrier to ameliorate acute ischemic stroke. Biorxiv : the Preprint Server For Biology. PMID 37398465 DOI: 10.1101/2023.06.12.544645  0.331
2023 Reyes-Esteves S, Nong J, Glassman PM, Omo-Lamai S, Ohashi S, Myerson JW, Zamora ME, Ma X, Kasner SE, Sansing L, Muzykantov VR, Marcos-Contreras OA, Brenner JS. Targeted drug delivery to the brain endothelium dominates over passive delivery via vascular leak in experimental intracerebral hemorrhage. Journal of Controlled Release : Official Journal of the Controlled Release Society. 356: 185-195. PMID 36868517 DOI: 10.1016/j.jconrel.2023.02.037  0.362
2022 Zhao Z, Kim J, Suja VC, Kapate N, Gao Y, Guo J, Muzykantov VR, Mitragotri S. Red Blood Cell Anchoring Enables Targeted Transduction and Re-Administration of AAV-Mediated Gene Therapy. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2201293. PMID 35780495 DOI: 10.1002/advs.202201293  0.327
2022 Glassman PM, Villa CH, Marcos-Contreras OA, Hood ED, Walsh LR, Greineder CF, Myerson JW, Shuvaeva T, Puentes L, Brenner JS, Siegel DL, Muzykantov VR. Targeted In Vivo Loading of Red Blood Cells Markedly Prolongs Nanocarrier Circulation. Bioconjugate Chemistry. PMID 35710322 DOI: 10.1021/acs.bioconjchem.2c00196  0.711
2022 Nong J, Glassman PM, Muzykantov VR. Targeting vascular inflammation through emerging methods and drug carriers. Advanced Drug Delivery Reviews. 184: 114180. PMID 35271986 DOI: 10.1016/j.addr.2022.114180  0.381
2022 Ferguson LT, Hood ED, Shuvaeva T, Shuvaev VV, Basil MC, Wang Z, Nong J, Ma X, Wu J, Myerson JW, Marcos-Contreras OA, Katzen J, Carl JM, Morrisey EE, Cantu E, ... ... Muzykantov VR, et al. Dual Affinity to RBCs and Target Cells (DART) Enhances Both Organ- and Cell Type-Targeting of Intravascular Nanocarriers. Acs Nano. PMID 35266686 DOI: 10.1021/acsnano.1c11374  0.37
2021 Myerson JW, Patel PN, Rubey KM, Zamora ME, Zaleski MH, Habibi N, Walsh LR, Lee YW, Luther DC, Ferguson LT, Marcos-Contreras OA, Glassman PM, Mazaleuskaya LL, Johnston I, Hood ED, ... ... Muzykantov VR, et al. Supramolecular arrangement of protein in nanoparticle structures predicts nanoparticle tropism for neutrophils in acute lung inflammation. Nature Nanotechnology. PMID 34795440 DOI: 10.1038/s41565-021-00997-y  0.626
2021 Brenner JS, Mitragotri S, Muzykantov VR. Red Blood Cell Hitchhiking: A Novel Approach for Vascular Delivery of Nanocarriers. Annual Review of Biomedical Engineering. PMID 33788581 DOI: 10.1146/annurev-bioeng-121219-024239  0.305
2021 Muzykantov V, Muro S. Targeting delivery of drugs in the vascular system. International Journal of Transport Phenomena. 12: 41-49. PMID 25328360  0.424
2020 Kiseleva RY, Glassman PG, LeForte KM, Walsh LR, Villa CH, Shuvaev VV, Myerson JW, Aprelev PA, Marcos-Contreras OA, Muzykantov VR, Greineder CF. Bivalent engagement of endothelial surface antigens is critical to prolonged surface targeting and protein delivery in vivo. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32738178 DOI: 10.1096/Fj.201902515Rr  0.693
2020 Ukidve A, Zhao Z, Fehnel A, Krishnan V, Pan DC, Gao Y, Mandal A, Muzykantov V, Mitragotri S. Erythrocyte-driven immunization via biomimicry of their natural antigen-presenting function. Proceedings of the National Academy of Sciences of the United States of America. PMID 32665441 DOI: 10.1073/Pnas.2002880117  0.334
2020 Glassman PM, Myerson JW, Ferguson LT, Kiseleva RY, Shuvaev VV, Brenner JS, Muzykantov VR. Targeting drug delivery in the vascular system: Focus on endothelium. Advanced Drug Delivery Reviews. PMID 32579890 DOI: 10.1016/J.Addr.2020.06.013  0.513
2020 Glassman PM, Muzykantov VR. Target-mediated exposure enhancement: a previously unexplored limit of TMDD. Journal of Pharmacokinetics and Pharmacodynamics. PMID 32488574 DOI: 10.1007/S10928-020-09693-1  0.437
2020 Glassman PM, Villa CH, Ukidve A, Zhao Z, Smith P, Mitragotri S, Russell AJ, Brenner JS, Muzykantov VR. Vascular Drug Delivery Using Carrier Red Blood Cells: Focus on RBC Surface Loading and Pharmacokinetics. Pharmaceutics. 12. PMID 32397513 DOI: 10.3390/Pharmaceutics12050440  0.386
2020 Glassman PM, Walsh LR, Villa CH, Marcos-Contreras OA, Hood ED, Muzykantov VR, Greineder CF. Molecularly Engineered Nanobodies for Tunable Pharmacokinetics and Drug Delivery. Bioconjugate Chemistry. PMID 32167754 DOI: 10.1021/Acs.Bioconjchem.0C00003  0.752
2020 Marcos-Contreras OA, Greineder CF, Kiseleva RY, Parhiz H, Walsh LR, Zuluaga-Ramirez V, Myerson JW, Hood ED, Villa CH, Tombacz I, Pardi N, Seliga A, Mui BL, Tam YK, Glassman PM, ... ... Muzykantov VR, et al. Selective targeting of nanomedicine to inflamed cerebral vasculature to enhance the blood-brain barrier. Proceedings of the National Academy of Sciences of the United States of America. PMID 32005712 DOI: 10.1073/Pnas.1912012117  0.702
2019 Peghaire C, Dufton NP, Lang M, Salles-Crawley II, Ahnström J, Kalna V, Raimondi C, Pericleous C, Inuabasi L, Kiseleva R, Muzykantov VR, Mason JC, Birdsey GM, Randi AM. The transcription factor ERG regulates a low shear stress-induced anti-thrombotic pathway in the microvasculature. Nature Communications. 10: 5014. PMID 31676784 DOI: 10.1038/S41467-019-12897-W  0.378
2019 Ji W, Smith PN, Koepsel RR, Andersen JD, Baker SL, Zhang L, Carmali S, Myerson JW, Muzykantov V, Russell AJ. Erythrocytes as Carriers of Immunoglobulin-Based Therapeutics. Acta Biomaterialia. PMID 31669698 DOI: 10.1016/J.Actbio.2019.10.027  0.441
2019 Myerson JW, McPherson O, DeFrates KG, Towslee JH, Marcos-Contreras OA, Shuvaev VV, Braender B, Composto RJ, Muzykantov VR, Eckmann DM. Cross-linker-Modulated Nanogel Flexibility Correlates with Tunable Targeting to a Sterically Impeded Endothelial Marker. Acs Nano. PMID 31600053 DOI: 10.1021/Acsnano.9B04789  0.4
2019 Khoshnejad M, Brenner JS, Parhiz H, Muzykantov VR. CRISPR/Cas9-Mediated Genetic Engineering of Hybridomas for Creation of Antibodies that Allow for Site-Specific Conjugation. Methods in Molecular Biology (Clifton, N.J.). 2033: 81-93. PMID 31332749 DOI: 10.1007/978-1-4939-9654-4_7  0.36
2019 Lutton EM, Farney SK, Andrews AM, Shuvaev VV, Chuang GY, Muzykantov VR, Ramirez SH. Endothelial Targeted Strategies to Combat Oxidative Stress: Improving Outcomes in Traumatic Brain Injury. Frontiers in Neurology. 10: 582. PMID 31275220 DOI: 10.3389/Fneur.2019.00582  0.46
2019 Paek J, Park SE, Lu Q, Park KT, Cho M, Oh JM, Kwon KW, Yi YS, Song JW, Edelstein HI, Ishibashi J, Yang W, Myerson JW, Kiseleva RY, Aprelev P, ... ... Muzykantov VR, et al. Microphysiological Engineering of Self-Assembled and Perfusable Microvascular Beds for the Production of Vascularized Three-Dimensional Human Microtissues. Acs Nano. PMID 31194909 DOI: 10.1021/Acsnano.9B00686  0.427
2019 Farokhirad S, Ranganathan A, Myerson J, Muzykantov VR, Ayyaswamy PS, Eckmann DM, Radhakrishnan R. Stiffness can mediate balance between hydrodynamic forces and avidity to impact the targeting of flexible polymeric nanoparticles in flow. Nanoscale. PMID 30912772 DOI: 10.1039/C8Nr09594A  0.354
2019 Marcos-Contreras OA, Brenner JS, Kiseleva RY, Zuluaga-Ramirez V, Greineder CF, Villa CH, Hood ED, Myerson JW, Muro S, Persidsky Y, Muzykantov VR. Combining vascular targeting and the local first pass provides 100-fold higher uptake of ICAM-1-targeted vs untargeted nanocarriers in the inflamed brain. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 30871995 DOI: 10.1016/J.Jconrel.2019.03.008  0.718
2019 Glassman PM, Muzykantov VR. Pharmacokinetics, Biodistribution, and Pharmacodynamics of Drug Delivery Systems. The Journal of Pharmacology and Experimental Therapeutics. PMID 30837281 DOI: 10.1124/Jpet.119.257113  0.375
2018 Parhiz H, Shuvaev VV, Pardi N, Khoshnejad M, Kiseleva RY, Brenner JS, Uhler T, Tuyishime S, Mui BL, Tam YK, Madden TD, Hope MJ, Weissman D, Muzykantov VR. PECAM-1 directed re-targeting of exogenous mRNA providing two orders of magnitude enhancement of vascular delivery and expression in lungs independent of apolipoprotein E-mediated uptake. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 30336167 DOI: 10.1016/J.Jconrel.2018.10.015  0.396
2018 Shuvaev VV, Khoshnejad M, Pulsipher KW, Kiseleva RY, Arguiri E, Cheung-Lau JC, LeFort KM, Christofidou-Solomidou M, Stan RV, Dmochowski IJ, Muzykantov VR. Spatially controlled assembly of affinity ligand and enzyme cargo enables targeting ferritin nanocarriers to caveolae. Biomaterials. 185: 348-359. PMID 30273834 DOI: 10.1016/J.Biomaterials.2018.09.015  0.504
2018 Hood ED, Greineder CF, Shuvaeva T, Walsh L, Villa CH, Muzykantov VR. Vascular targeting of radiolabeled liposomes with bio-orthogonally conjugated ligands: single chain fragments provide higher specificity than antibodies. Bioconjugate Chemistry. PMID 30240185 DOI: 10.1021/Acs.Bioconjchem.8B00564  0.752
2018 Parhiz H, Khoshnejad M, Myerson JW, Hood E, Patel PN, Brenner JS, Muzykantov VR. Unintended effects of drug carriers: Big issues of small particles. Advanced Drug Delivery Reviews. 130: 90-112. PMID 30149885 DOI: 10.1016/J.Addr.2018.06.023  0.327
2018 Muzykantov VR, Brenner JS. Vascular Immunotargeting: Take the Highway to the First Exit. Hepatology (Baltimore, Md.). PMID 30070712 DOI: 10.1002/Hep.30141  0.344
2018 Brenner JS, Pan DC, Myerson JW, Marcos-Contreras OA, Villa CH, Patel P, Hekierski H, Chatterjee S, Tao JQ, Parhiz H, Bhamidipati K, Uhler TG, Hood ED, Kiseleva RY, Shuvaev VS, ... ... Muzykantov V, et al. Red blood cell-hitchhiking boosts delivery of nanocarriers to chosen organs by orders of magnitude. Nature Communications. 9: 2684. PMID 29992966 DOI: 10.1038/S41467-018-05079-7  0.42
2018 Myerson JW, Braender B, Mcpherson O, Glassman PM, Kiseleva RY, Shuvaev VV, Marcos-Contreras O, Grady ME, Lee HS, Greineder CF, Stan RV, Composto RJ, Eckmann DM, Muzykantov VR. Flexible Nanoparticles Reach Sterically Obscured Endothelial Targets Inaccessible to Rigid Nanoparticles. Advanced Materials (Deerfield Beach, Fla.). e1802373. PMID 29956381 DOI: 10.1002/Adma.201802373  0.713
2018 Khoshnejad M, Parhiz H, Shuvaev VV, Dmochowski IJ, Muzykantov VR. Ferritin-based drug delivery systems: Hybrid nanocarriers for vascular immunotargeting. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 29522833 DOI: 10.1016/J.Jconrel.2018.02.042  0.441
2018 Khoshnejad M, Greineder CF, Pulsipher KW, Villa CH, Altun B, Pan DC, Tsourkas A, Dmochowski IJ, Muzykantov V. Ferritin nanocages with biologically orthogonal conjugation for vascular targeting and imaging. Bioconjugate Chemistry. PMID 29429330 DOI: 10.1021/Acs.Bioconjchem.8B00004  0.729
2018 Khoshnejad M, Brenner JS, Motley W, Parhiz H, Greineder CF, Villa CH, Marcos-Contreras OA, Tsourkas A, Muzykantov VR. Molecular engineering of antibodies for site-specific covalent conjugation using CRISPR/Cas9. Scientific Reports. 8: 1760. PMID 29379029 DOI: 10.1038/S41598-018-19784-2  0.696
2018 Pan DC, Myerson JW, Brenner JS, Patel PN, Anselmo AC, Mitragotri S, Muzykantov V. Nanoparticle Properties Modulate Their Attachment and Effect on Carrier Red Blood Cells. Scientific Reports. 8: 1615. PMID 29371620 DOI: 10.1038/S41598-018-19897-8  0.354
2018 Kiseleva RY, Greineder CF, Villa CH, Marcos-Contreras OA, Hood ED, Shuvaev VV, DeLisser HM, Muzykantov VR. Vascular endothelial effects of collaborative binding to platelet/endothelial cell adhesion molecule-1 (PECAM-1). Scientific Reports. 8: 1510. PMID 29367646 DOI: 10.1038/S41598-018-20027-7  0.764
2018 Villa CH, Pan DC, Johnston IH, Greineder CF, Walsh LR, Hood ED, Cines DB, Poncz M, Siegel DL, Muzykantov VR. Biocompatible coupling of therapeutic fusion proteins to human erythrocytes. Blood Advances. 2: 165-176. PMID 29365311 DOI: 10.1182/Bloodadvances.2017011734  0.727
2018 Uhl CG, Muzykantov VR, Liu Y. Biomimetic microfluidic platform for the quantification of transient endothelial monolayer permeability and therapeutic transport under mimicked cancerous conditions. Biomicrofluidics. 12: 014101. PMID 29333203 DOI: 10.1063/1.5000377  0.373
2018 Lyde R, Ahn H, Hayes V, Zaistev S, Lin S, Ruggeri ZM, Li R, Muzykantov V, Cines DB, Poncz M. A Novel Anti-Glycoprotein (GP) Iba-Targeting Chimeric Fibrinolytic Agent Demonstrates In Vivo Efficacy Against Human Platelet-Enriched Thrombi in Mice Blood. 132: 990-990. DOI: 10.1182/Blood-2018-99-115262  0.334
2017 Greineder CF, Johnston IH, Villa CH, Gollomp K, Esmon CT, Cines DB, Poncz M, Muzykantov VR. ICAM-1-targeted thrombomodulin mitigates tissue factor-driven inflammatory thrombosis in a human endothelialized microfluidic model. Blood Advances. 1: 1452-1465. PMID 29296786 DOI: 10.1182/Bloodadvances.2017007229  0.734
2017 Shuvaev VV, Kiseleva RY, Arguiri E, Villa CH, Muro S, Christofidou-Solomidou M, Stan RV, Muzykantov VR. Targeting superoxide dismutase to endothelial caveolae profoundly alleviates inflammation caused by endotoxin. Journal of Controlled Release : Official Journal of the Controlled Release Society. 272: 1-8. PMID 29292038 DOI: 10.1016/J.Jconrel.2017.12.025  0.435
2017 Kiseleva RY, Glassman PM, Greineder CF, Hood ED, Shuvaev VV, Muzykantov VR. Targeting therapeutics to endothelium: are we there yet? Drug Delivery and Translational Research. PMID 29282646 DOI: 10.1007/S13346-017-0464-6  0.757
2017 Brenner JS, Kiseleva RY, Glassman PM, Parhiz H, Greineder CF, Hood ED, Shuvaev VV, Muzykantov VR. EXPRESS: The new frontiers of the targeted interventions in the pulmonary vasculature: precision and safety. Pulmonary Circulation. 2045893217752329. PMID 29261028 DOI: 10.1177/2045893217752329  0.721
2017 Greineder CF, Villa CH, Walsh LR, Kiseleva RY, Hood ED, Khoshnejad M, Warden-Rothman R, Tsourkas A, Muzykantov VR. Site-specific modification of single-chain antibody fragments for bioconjugation and vascular immunotargeting. Bioconjugate Chemistry. PMID 29200285 DOI: 10.1021/Acs.Bioconjchem.7B00592  0.761
2017 Ranganathan A, Campo J, Myerson J, Shuvaev V, Zern B, Muzykantov V, Eckmann DM. Fluorescence Microscopy Imaging Calibration for Quantifying Nanocarrier Binding to Cells During Shear Flow Exposure. Journal of Biomedical Nanotechnology. 13: 737-745. PMID 29104516 DOI: 10.1166/Jbn.2017.2392  0.361
2017 Goitre L, DiStefano PV, Moglia A, Nobiletti N, Baldini E, Trabalzini L, Keubel J, Trapani E, Shuvaev VV, Muzykantov VR, Sarelius IH, Retta SF, Glading AJ. Up-regulation of NADPH oxidase-mediated redox signaling contributes to the loss of barrier function in KRIT1 deficient endothelium. Scientific Reports. 7: 8296. PMID 28811547 DOI: 10.1038/S41598-017-08373-4  0.349
2017 Lutton EM, Razmpour R, Andrews AM, Cannella LA, Son YJ, Shuvaev VV, Muzykantov VR, Ramirez SH. Acute administration of catalase targeted to ICAM-1 attenuates neuropathology in experimental traumatic brain injury. Scientific Reports. 7: 3846. PMID 28630485 DOI: 10.1038/S41598-017-03309-4  0.405
2017 Kiseleva R, Greineder CF, Villa CH, Hood ED, Shuvaev VV, Sun J, Chacko AM, Abraham V, DeLisser HM, Muzykantov VR. Mechanism of Collaborative Enhancement of Binding of Paired Antibodies to Distinct Epitopes of Platelet Endothelial Cell Adhesion Molecule-1. Plos One. 12: e0169537. PMID 28085903 DOI: 10.1371/Journal.Pone.0169537  0.733
2017 Brenner JS, Bhamidipati K, Glassman P, Ramakrishnan N, Jiang D, Paris AJ, Myerson JW, Pan DC, Shuvaev VV, Villa C, Hood ED, Kiseleva R, Greineder CF, Radhakrishnan R, Muzykantov VR. Mechanisms that determine nanocarrier targeting to healthy versus inflamed lung regions. Nanomedicine : Nanotechnology, Biology, and Medicine. PMID 28065731 DOI: 10.1016/J.Nano.2016.12.019  0.671
2016 Villa CH, Seghatchian J, Muzykantov V. Drug delivery by erythrocytes: "Primum non nocere". Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society For Haemapheresis. PMID 27856317 DOI: 10.1016/J.Transci.2016.10.017  0.384
2016 Carnemolla R, Villa CH, Greineder CF, Zaitsev S, Patel KR, Kowalska MA, Atochin DN, Cines DB, Siegel DL, Esmon CT, Muzykantov VR. Targeting thrombomodulin to circulating red blood cells augments its protective effects in models of endotoxemia and ischemia-reperfusion injury. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 27836986 DOI: 10.1096/Fj.201600912R  0.708
2016 Villa CH, Cines DB, Siegel DL, Muzykantov V. Erythrocytes as Carriers for Drug Delivery in Blood Transfusion and Beyond. Transfusion Medicine Reviews. PMID 27707522 DOI: 10.1016/J.Tmrv.2016.08.004  0.404
2016 Ramakrishnan N, Tourdot RW, Eckmann DM, Ayyaswamy PS, Muzykantov VR, Radhakrishnan R. Biophysically inspired model for functionalized nanocarrier adhesion to cell surface: roles of protein expression and mechanical factors. Royal Society Open Science. 3: 160260. PMID 27429783 DOI: 10.1098/Rsos.160260  0.415
2016 Shuvaev VV, Muro S, Arguiri E, Khoshnejad M, Tliba S, Christofidou-Solomidou M, Muzykantov VR. Size and targeting to PECAM vs ICAM control endothelial delivery, internalization and protective effect of multimolecular SOD conjugates. Journal of Controlled Release : Official Journal of the Controlled Release Society. 234: 115-23. PMID 27210108 DOI: 10.1016/J.Jconrel.2016.05.040  0.52
2016 Daiber A, Steven S, Weber A, Shuvaev VV, Muzykantov VR, Laher I, Li H, Lamas S, Münzel T. Targeting vascular (endothelial) dysfunction. British Journal of Pharmacology. PMID 27187006 DOI: 10.1111/Bph.13517  0.409
2016 Pan D, Vargas-Morales O, Zern B, Anselmo AC, Gupta V, Zakrewsky M, Mitragotri S, Muzykantov V. The Effect of Polymeric Nanoparticles on Biocompatibility of Carrier Red Blood Cells. Plos One. 11: e0152074. PMID 27003833 DOI: 10.1371/Journal.Pone.0152074  0.394
2016 Villa CH, Anselmo AC, Mitragotri S, Muzykantov V. Red blood cells: Supercarriers for drugs, biologicals, and nanoparticles and inspiration for Advanced Delivery Systems. Advanced Drug Delivery Reviews. PMID 26941164 DOI: 10.1016/J.Addr.2016.02.007  0.393
2016 Thomas A, Daniel Ou-Yang H, Lowe-Krentz L, Muzykantov VR, Liu Y. Biomimetic channel modeling local vascular dynamics of pro-inflammatory endothelial changes. Biomicrofluidics. 10: 014101. PMID 26858813 DOI: 10.1063/1.4936672  0.444
2016 Greineder CF, Hood ED, Yao A, Khoshnejad M, Brenner JS, Johnston IH, Poncz M, Gottstein C, Muzykantov VR. Molecular engineering of high affinity single-chain antibody fragment for endothelial targeting of proteins and nanocarriers in rodents and humans. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 26855052 DOI: 10.1016/J.Jconrel.2016.02.006  0.758
2016 Villa CH, Pan D, Johnston I, Greineder CF, Reid ME, Cines DB, Poncz M, Siegel DL, Muzykantov VR. Coupling Therapeutics to Human Erythrocytes Demonstrates Target-Dependent Effects on Red Cell Physiology While Preserving Efficacy Blood. 128: 701-701. DOI: 10.1182/Blood.V128.22.701.701  0.736
2016 Tutwiler V, Litvinov RI, Nagaswami C, Russell JE, Siegel DL, Villa CH, Pan D, Muzykantov VR, Weisel JW. Erythrocyte Rigidity Affects Blood Clot Contraction and Formation of Polyhedrocytes Blood. 128: 3814-3814. DOI: 10.1182/Blood.V128.22.3814.3814  0.344
2016 Greineder CF, Johnston I, Villa CH, Cines DB, Poncz M, Muzykantov VR. Simultaneous Replacement of Endothelial Thrombomodulin and Plasma Protein C: A Novel Therapeutic Strategy for Sepsis-Induced Disseminated Intravascular Coagulation Blood. 128: 2613-2613. DOI: 10.1182/Blood.V128.22.2613.2613  0.697
2016 Villa CH, Muzykantov VR, Cines DB. The emerging role for red blood cells in haemostasis: opportunity for intervention Isbt Science Series. 11: 158-164. DOI: 10.1111/Voxs.12197  0.399
2015 Khoshnejad M, Shuvaev V, Pulsipher KW, Dai C, Hood ED, Arguiri E, Christofidou-Solomidou M, Dmochowski IJ, Greineder CF, Muzykantov VR. Vascular Accessibility of Endothelial Targeted Ferritin Nanoparticles. Bioconjugate Chemistry. PMID 26718023 DOI: 10.1021/Acs.Bioconjchem.5B00641  0.734
2015 Fuentes RE, Zaitsev S, Ahn HS, Hayes V, Kowalska MA, Lambert MP, Wang Y, Siegel DL, Bougie DW, Aster RH, Myers DD, Stepanova V, Cines DB, Muzykantov VR, Poncz M. A chimeric platelet-targeted urokinase prodrug selectively blocks new thrombus formation. The Journal of Clinical Investigation. PMID 26690701 DOI: 10.1172/Jci81470  0.382
2015 Jordan C, Shuvaev VV, Bailey M, Muzykantov VR, Dziubla TD. The Role of Carrier Geometry in Overcoming Biological Barriers to Drug Delivery. Current Pharmaceutical Design. PMID 26675218 DOI: 10.2174/1381612822666151216151856  0.38
2015 Myerson JW, Anselmo AC, Liu Y, Mitragotri S, Eckmann DM, Muzykantov VR. Non-affinity factors modulating vascular targeting of nano- and microcarriers. Advanced Drug Delivery Reviews. PMID 26596696 DOI: 10.1016/J.Addr.2015.10.011  0.461
2015 Rahmani S, Villa CH, Dishman AF, Grabowski ME, Pan DC, Durmaz H, Misra AC, Colón-Meléndez L, Solomon MJ, Muzykantov VR, Lahann J. Long-circulating Janus nanoparticles made by electrohydrodynamic co-jetting for systemic drug delivery applications. Journal of Drug Targeting. 23: 750-8. PMID 26453170 DOI: 10.3109/1061186X.2015.1076428  0.316
2015 Shuvaev VV, Brenner JS, Muzykantov VR. Targeted endothelial nanomedicine for common acute pathological conditions. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 26435455 DOI: 10.1016/J.Jconrel.2015.09.055  0.544
2015 Anselmo AC, Kumar S, Gupta V, Pearce AM, Ragusa A, Muzykantov V, Mitragotri S. Exploiting shape, cellular-hitchhiking and antibodies to target nanoparticles to lung endothelium: Synergy between physical, chemical and biological approaches. Biomaterials. 68: 1-8. PMID 26241497 DOI: 10.1016/J.Biomaterials.2015.07.043  0.405
2015 Villa CH, Pan DC, Zaitsev S, Cines DB, Siegel DL, Muzykantov VR. Delivery of drugs bound to erythrocytes: new avenues for an old intravascular carrier. Therapeutic Delivery. 6: 795-826. PMID 26228773 DOI: 10.4155/Tde.15.34  0.423
2015 Chacko AM, Han J, Greineder CF, Zern BJ, Mikitsh JL, Nayak M, Menon D, Johnston IH, Poncz M, Eckmann DM, Davies PF, Muzykantov VR. Collaborative Enhancement of Endothelial Targeting of Nanocarriers by Modulating Platelet-Endothelial Cell Adhesion Molecule-1/CD31 Epitope Engagement. Acs Nano. 9: 6785-93. PMID 26153796 DOI: 10.1021/Nn505672X  0.74
2015 Han J, Shuvaev VV, Davies PF, Eckmann DM, Muro S, Muzykantov VR. Flow shear stress differentially regulates endothelial uptake of nanocarriers targeted to distinct epitopes of PECAM-1. Journal of Controlled Release : Official Journal of the Controlled Release Society. 210: 39-47. PMID 25966362 DOI: 10.1016/J.Jconrel.2015.05.006  0.472
2015 Greineder CF, Brenza JB, Carnemolla R, Zaitsev S, Hood ED, Pan DC, Ding BS, Esmon CT, Chacko AM, Muzykantov VR. Dual targeting of therapeutics to endothelial cells: collaborative enhancement of delivery and effect. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 25953848 DOI: 10.1096/Fj.15-271213  0.835
2015 Myerson JW, Brenner JS, Greineder CF, Muzykantov VR. Systems approaches to design of targeted therapeutic delivery. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. PMID 25946066 DOI: 10.1002/Wsbm.1304  0.73
2015 Brenner JS, Greineder C, Shuvaev V, Muzykantov V. Endothelial nanomedicine for the treatment of pulmonary disease. Expert Opinion On Drug Delivery. 12: 239-61. PMID 25394760 DOI: 10.1517/17425247.2015.961418  0.655
2015 Villa CH, Greineder CF, Johnston I, Pan D, Carnemolla R, Cines DB, Poncz M, Siegel DL, Muzykantov VR. Thrombomodulin Fusion Proteins Coupled to Human Erythrocytes Demonstrate Anti-Thrombotic and Anti-Inflammatory Activity Blood. 126: 3493-3493. DOI: 10.1182/Blood.V126.23.3493.3493  0.731
2015 Greineder CF, Johnston I, Villa CH, Cines DB, Poncz M, Muzykantov VR. A Microfluidic Model of Microvascular Inflammation: Characterization and Testing of Endothelial-Targeted Therapeutics Blood. 126: 3454-3454. DOI: 10.1182/Blood.V126.23.3454.3454  0.747
2015 Chacko AM, Han J, Greineder CF, Zern BJ, Mikitsh JL, Nayak M, Menon D, Johnston IH, Poncz M, Eckmann DM, Davies PF, Muzykantov VR. Collaborative Enhancement of Endothelial Targeting of Nanocarriers by Modulating Platelet-Endothelial Cell Adhesion Molecule-1/CD31 Epitope Engagement Acs Nano. 9: 6785-6793. DOI: 10.1021/nn505672x  0.689
2014 Eckmann DM, Composto RJ, Tsourkas A, Muzykantov VR. Nanogel Carrier Design for Targeted Drug Delivery. Journal of Materials Chemistry. B, Materials For Biology and Medicine. 2: 8085-8097. PMID 25485112 DOI: 10.1039/C4Tb01141D  0.434
2014 Li C, Wang J, Hu J, Feng Y, Hasegawa K, Peng X, Duan X, Zhao A, Mikitsh JL, Muzykantov VR, Chacko AM, Pryma DA, Dunn SM, Coukos G. Development, optimization, and validation of novel anti-TEM1/CD248 affinity agent for optical imaging in cancer. Oncotarget. 5: 6994-7012. PMID 25051365 DOI: 10.18632/Oncotarget.2188  0.382
2014 Ferrer MC, Shuvaev VV, Zern BJ, Composto RJ, Muzykantov VR, Eckmann DM. Icam-1 targeted nanogels loaded with dexamethasone alleviate pulmonary inflammation. Plos One. 9: e102329. PMID 25019304 DOI: 10.1371/Journal.Pone.0102329  0.483
2014 Howard MD, Hood ED, Greineder CF, Alferiev IS, Chorny M, Muzykantov V. Targeting to endothelial cells augments the protective effect of novel dual bioactive antioxidant/anti-inflammatory nanoparticles. Molecular Pharmaceutics. 11: 2262-70. PMID 24877560 DOI: 10.1021/Mp400677Y  0.719
2014 Howard M, Zern BJ, Anselmo AC, Shuvaev VV, Mitragotri S, Muzykantov V. Vascular targeting of nanocarriers: perplexing aspects of the seemingly straightforward paradigm. Acs Nano. 8: 4100-32. PMID 24787360 DOI: 10.1021/Nn500136Z  0.523
2014 Li C, Chacko AM, Hu J, Hasegawa K, Swails J, Grasso L, El-Deiry WS, Nicolaides N, Muzykantov VR, Divgi CR, Coukos G. Antibody-based tumor vascular theranostics targeting endosialin/TEM1 in a new mouse tumor vascular model. Cancer Biology & Therapy. 15: 443-51. PMID 24553243 DOI: 10.4161/Cbt.27825  0.376
2014 Chacko AM, Li C, Nayak M, Mikitsh JL, Hu J, Hou C, Grasso L, Nicolaides NC, Muzykantov VR, Divgi CR, Coukos G. Development of 124I immuno-PET targeting tumor vascular TEM1/endosialin. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 55: 500-7. PMID 24525208 DOI: 10.2967/Jnumed.113.121905  0.407
2014 Hood ED, Chorny M, Greineder CF, S Alferiev I, Levy RJ, Muzykantov VR. Endothelial targeting of nanocarriers loaded with antioxidant enzymes for protection against vascular oxidative stress and inflammation. Biomaterials. 35: 3708-15. PMID 24480537 DOI: 10.1016/J.Biomaterials.2014.01.023  0.737
2014 Howard MD, Greineder CF, Hood ED, Muzykantov VR. Endothelial targeting of liposomes encapsulating SOD/catalase mimetic EUK-134 alleviates acute pulmonary inflammation. Journal of Controlled Release : Official Journal of the Controlled Release Society. 177: 34-41. PMID 24412573 DOI: 10.1016/J.Jconrel.2013.12.035  0.754
2014 Howard MD, Hood ED, Zern B, Shuvaev VV, Grosser T, Muzykantov VR. Nanocarriers for vascular delivery of anti-inflammatory agents. Annual Review of Pharmacology and Toxicology. 54: 205-26. PMID 24392694 DOI: 10.1146/Annurev-Pharmtox-011613-140002  0.457
2014 Orndorff RL, Hong N, Yu K, Feinstein SI, Zern BJ, Fisher AB, Muzykantov VR, Chatterjee S. NOX2 in lung inflammation: quantum dot based in situ imaging of NOX2-mediated expression of vascular cell adhesion molecule-1. American Journal of Physiology. Lung Cellular and Molecular Physiology. 306: L260-8. PMID 24318114 DOI: 10.1152/Ajplung.00278.2013  0.401
2014 Li C, Wang J, Matthaiou EI, Guo Y, Hu J, Chacko AM, Muzykantov VR, Coukos G. Immuno-imaging and -therapy in ovarian cancer and sarcoma with de novo single-chain fv-fc fusion protein targeting TEM1/CD248 Journal For Immunotherapy of Cancer. 2. DOI: 10.1186/2051-1426-2-S3-P219  0.404
2014 Ahn HS, Fuentes R, Hayes V, Cines DB, Muzykantov VR, Zaytsev SV, Poncz M. A Human-Specific, Platelet-Targeted, Thrombin-Activatable Urokinase (PLT/uPA-T) Demonstrates Selective Thromboprophylactic Properties in Two in Vivo Models Blood. 124: 579-579. DOI: 10.1182/Blood.V124.21.579.579  0.378
2013 Greineder CF, Chacko AM, Zaytsev S, Zern BJ, Carnemolla R, Hood ED, Han J, Ding BS, Esmon CT, Muzykantov VR. Vascular immunotargeting to endothelial determinant ICAM-1 enables optimal partnering of recombinant scFv-thrombomodulin fusion with endogenous cofactor. Plos One. 8: e80110. PMID 24244621 DOI: 10.1371/Journal.Pone.0080110  0.82
2013 Anselmo AC, Gupta V, Zern BJ, Pan D, Zakrewsky M, Muzykantov V, Mitragotri S. Delivering nanoparticles to lungs while avoiding liver and spleen through adsorption on red blood cells. Acs Nano. 7: 11129-37. PMID 24182189 DOI: 10.1021/Nn404853Z  0.394
2013 Shuvaev VV, Han J, Tliba S, Arguiri E, Christofidou-Solomidou M, Ramirez SH, Dykstra H, Persidsky Y, Atochin DN, Huang PL, Muzykantov VR. Anti-inflammatory effect of targeted delivery of SOD to endothelium: mechanism, synergism with NO donors and protective effects in vitro and in vivo. Plos One. 8: e77002. PMID 24146950 DOI: 10.1371/Journal.Pone.0077002  0.484
2013 Carnemolla R, Greineder CF, Chacko AM, Patel KR, Ding BS, Zaitsev S, Esmon CT, Muzykantov VR. Platelet endothelial cell adhesion molecule targeted oxidant-resistant mutant thrombomodulin fusion protein with enhanced potency in vitro and in vivo. The Journal of Pharmacology and Experimental Therapeutics. 347: 339-45. PMID 23965383 DOI: 10.1124/Jpet.113.205104  0.805
2013 Ayyaswamy PS, Muzykantov V, Eckmann DM, Radhakrishnan R. Nanocarrier Hydrodynamics and Binding in Targeted Drug Delivery: Challenges in Numerical Modeling and Experimental Validation. Journal of Nanotechnology in Engineering and Medicine. 4: 101011-1010115. PMID 23917383 DOI: 10.1115/1.4024004  0.431
2013 Greineder CF, Howard MD, Carnemolla R, Cines DB, Muzykantov VR. Advanced drug delivery systems for antithrombotic agents. Blood. 122: 1565-75. PMID 23798715 DOI: 10.1182/Blood-2013-03-453498  0.726
2013 Chacko AM, Li C, Pryma DA, Brem S, Coukos G, Muzykantov V. Targeted delivery of antibody-based therapeutic and imaging agents to CNS tumors: crossing the blood-brain barrier divide. Expert Opinion On Drug Delivery. 10: 907-26. PMID 23751126 DOI: 10.1517/17425247.2013.808184  0.385
2013 Zern BJ, Chacko AM, Liu J, Greineder CF, Blankemeyer ER, Radhakrishnan R, Muzykantov V. Reduction of nanoparticle avidity enhances the selectivity of vascular targeting and PET detection of pulmonary inflammation. Acs Nano. 7: 2461-9. PMID 23383962 DOI: 10.1021/Nn305773F  0.683
2013 Muzykantov VR. Drug delivery carriers on the fringes: natural red blood cells versus synthetic multilayered capsules. Expert Opinion On Drug Delivery. 10: 1-4. PMID 23176316 DOI: 10.1517/17425247.2013.750292  0.388
2013 Marcos-Contreras OA, Ganguly K, Yamamoto A, Shlansky-Goldberg R, Cines DB, Muzykantov VR, Murciano JC. Clot penetration and retention by plasminogen activators promote fibrinolysis. Biochemical Pharmacology. 85: 216-22. PMID 23098998 DOI: 10.1016/J.Bcp.2012.10.011  0.365
2013 Li C, Wang J, Hu J, Chacko AM, Zhao A, Divgi C, Muzykantov V, Coukos G. Immunotargeting of tumor vasculature: preclinical development of novel antibody-based imaging and therapy against TEM1/CD248 Journal For Immunotherapy of Cancer. 1. DOI: 10.1186/2051-1426-1-S1-P81  0.387
2013 Li C, Hu J, Chacko AM, Wang J, Zhao A, Duan X, Muzykantov V, Coukos G. Abstract B68: Targeted theranostics of tumor vasculature by multivalent scFv constructs against TEM1 Clinical Cancer Research. 19. DOI: 10.1158/1078-0432.Ovca13-B68  0.389
2013 Muzykantov VR. Targeted Drug Delivery to Endothelial Adhesion Molecules Isrn Vascular Medicine. 2013: 1-27. DOI: 10.1155/2013/916254  0.528
2012 Cheng Z, Al Zaki A, Hui JZ, Muzykantov VR, Tsourkas A. Multifunctional nanoparticles: cost versus benefit of adding targeting and imaging capabilities. Science (New York, N.Y.). 338: 903-10. PMID 23161990 DOI: 10.1126/Science.1226338  0.345
2012 Hood ED, Greineder CF, Dodia C, Han J, Mesaros C, Shuvaev VV, Blair IA, Fisher AB, Muzykantov VR. Antioxidant protection by PECAM-targeted delivery of a novel NADPH-oxidase inhibitor to the endothelium in vitro and in vivo Journal of Controlled Release. 163: 161-169. PMID 22974832 DOI: 10.1016/J.Jconrel.2012.08.031  0.713
2012 Han J, Zern BJ, Shuvaev VV, Davies PF, Muro S, Muzykantov V. Acute and chronic shear stress differently regulate endothelial internalization of nanocarriers targeted to platelet-endothelial cell adhesion molecule-1. Acs Nano. 6: 8824-36. PMID 22957767 DOI: 10.1021/Nn302687N  0.439
2012 Han J, Shuvaev VV, Muzykantov VR. Targeted interception of signaling reactive oxygen species in the vascular endothelium. Therapeutic Delivery. 3: 263-76. PMID 22834201 DOI: 10.4155/Tde.11.151  0.457
2012 Liu Y, Tan J, Thomas A, Ou-Yang D, Muzykantov VR. The shape of things to come: importance of design in nanotechnology for drug delivery. Therapeutic Delivery. 3: 181-94. PMID 22834196 DOI: 10.4155/Tde.11.156  0.329
2012 Carnemolla R, Patel KR, Zaitsev S, Cines DB, Esmon CT, Muzykantov VR. Quantitative analysis of thrombomodulin-mediated conversion of protein C to APC: translation from in vitro to in vivo. Journal of Immunological Methods. 384: 21-4. PMID 22750541 DOI: 10.1016/J.Jim.2012.06.012  0.346
2012 Simone EA, Zern BJ, Chacko AM, Mikitsh JL, Blankemeyer ER, Muro S, Stan RV, Muzykantov VR. Endothelial targeting of polymeric nanoparticles stably labeled with the PET imaging radioisotope iodine-124. Biomaterials. 33: 5406-13. PMID 22560201 DOI: 10.1016/J.Biomaterials.2012.04.036  0.796
2012 Chacko AM, Nayak M, Greineder CF, Delisser HM, Muzykantov VR. Collaborative enhancement of antibody binding to distinct PECAM-1 epitopes modulates endothelial targeting. Plos One. 7: e34958. PMID 22514693 DOI: 10.1371/Journal.Pone.0034958  0.766
2012 Zaitsev S, Kowalska MA, Neyman M, Carnemolla R, Tliba S, Ding BS, Stonestrom A, Spitzer D, Atkinson JP, Poncz M, Cines DB, Esmon CT, Muzykantov VR. Targeting recombinant thrombomodulin fusion protein to red blood cells provides multifaceted thromboprophylaxis. Blood. 119: 4779-85. PMID 22493296 DOI: 10.1182/Blood-2011-12-398149  0.709
2012 Muzykantov VR, Radhakrishnan R, Eckmann DM. Dynamic factors controlling targeting nanocarriers to vascular endothelium. Current Drug Metabolism. 13: 70-81. PMID 22292809 DOI: 10.2174/138920012798356916  0.514
2012 Pisapia JM, Xu X, Kelly J, Yeung J, Carrion G, Tong H, Meghan S, El-Falaky OM, Grady MS, Smith DH, Zaitsev S, Muzykantov VR, Stiefel MF, Stein SC. Microthrombosis after experimental subarachnoid hemorrhage: time course and effect of red blood cell-bound thrombin-activated pro-urokinase and clazosentan. Experimental Neurology. 233: 357-63. PMID 22079156 DOI: 10.1016/J.Expneurol.2011.10.029  0.322
2012 Bhowmick T, Berk E, Cui X, Muzykantov VR, Muro S. Effect of flow on endothelial endocytosis of nanocarriers targeted to ICAM-1. Journal of Controlled Release : Official Journal of the Controlled Release Society. 157: 485-92. PMID 21951807 DOI: 10.1016/J.Jconrel.2011.09.067  0.437
2012 Hood E, Simone E, Wattamwar P, Dziubla T, Muzykantov V. Nanocarriers for vascular delivery of antioxidants. Nanomedicine (London, England). 6: 1257-72. PMID 21929460 DOI: 10.2217/Nnm.11.92  0.825
2012 Muzykantov VR. 14 immunotargeting of catalase to the pulmonary vascular endothelium. Methods in Molecular Medicine. 25: 241-54. PMID 21318850 DOI: 10.1385/1-59259-075-6:241  0.486
2012 Greineder CF, Zaytsev S, Zern B, Chacko AM, Muzykantov VR. Targeting Thrombomodulin to Endothelial ICAM-1 Rather Than PECAM-1 Allows Partnering with the Endothelial Protein C Receptor and Enhances Protection of Endothelial Barrier Function Blood. 120: 3351-3351. DOI: 10.1182/Blood.V120.21.3351.3351  0.747
2012 Fuentes R, Ahn HS, Hayes VM, Tutwiler V, Wang Y, Bougie DW, Kowalska MA, Rauova L, Aster RH, Cines DB, Muzykantov VR, Poncz M, Zaitsev S. Platelet-Targeted, Thrombin-Activatable Fibrinolytic Pro-Drugs As Novel Therapies: Application to the Prothrombotic Disorder of Heparin-Induced Thrombocytopenia (HIT) Blood. 120: 1171-1171. DOI: 10.1182/Blood.V120.21.1171.1171  0.379
2011 Calderon AJ, Baig M, Pichette B, Muzykantov V, Muro S, Eckmann DM. Effect of Glycocalyx on Drug Delivery Carriers Targeted to Endothelial Cells. International Journal of Transport Phenomena. 12: 63-75. PMID 22679359  0.325
2011 Shuvaev VV, Ilies MA, Simone E, Zaitsev S, Kim Y, Cai S, Mahmud A, Dziubla T, Muro S, Discher DE, Muzykantov VR. Endothelial targeting of antibody-decorated polymeric filomicelles. Acs Nano. 5: 6991-9. PMID 21838300 DOI: 10.1021/Nn2015453  0.834
2011 Preissler G, Loehe F, Huff IV, Ebersberger U, Shuvaev VV, Bittmann I, Hermanns I, Kirkpatrick JC, Fischer K, Eichhorn ME, Winter H, Jauch KW, Albelda SM, Muzykantov VR, Wiewrodt R. Targeted endothelial delivery of nanosized catalase immunoconjugates protects lung grafts donated after cardiac death. Transplantation. 92: 380-7. PMID 21778930 DOI: 10.1097/Tp.0B013E318226Bc6B  0.394
2011 Carnemolla R, Muzykantov VR. Vascular targeting of antithrombotic agents. Iubmb Life. 63: 632-9. PMID 21766410 DOI: 10.1002/Iub.474  0.433
2011 Muzykantov VR. Targeted therapeutics and nanodevices for vascular drug delivery: quo vadis? Iubmb Life. 63: 583-5. PMID 21721101 DOI: 10.1002/Iub.480  0.476
2011 Chacko AM, Hood ED, Zern BJ, Muzykantov VR. Targeted Nanocarriers for Imaging and Therapy of Vascular Inflammation. Current Opinion in Colloid & Interface Science. 16: 215-227. PMID 21709761 DOI: 10.1016/J.Cocis.2011.01.008  0.462
2011 Han J, Shuvaev VV, Muzykantov VR. Catalase and superoxide dismutase conjugated with platelet-endothelial cell adhesion molecule antibody distinctly alleviate abnormal endothelial permeability caused by exogenous reactive oxygen species and vascular endothelial growth factor. The Journal of Pharmacology and Experimental Therapeutics. 338: 82-91. PMID 21474567 DOI: 10.1124/Jpet.111.180620  0.453
2011 Shuvaev VV, Muzykantov VR. Targeted modulation of reactive oxygen species in the vascular endothelium. Journal of Controlled Release : Official Journal of the Controlled Release Society. 153: 56-63. PMID 21457736 DOI: 10.1016/J.Jconrel.2011.03.022  0.506
2011 Calderon AJ, Bhowmick T, Leferovich J, Burman B, Pichette B, Muzykantov V, Eckmann DM, Muro S. Optimizing endothelial targeting by modulating the antibody density and particle concentration of anti-ICAM coated carriers Journal of Controlled Release. 150: 37-44. PMID 21047540 DOI: 10.1016/J.Jconrel.2010.10.025  0.51
2011 Shuvaev VV, Tliba S, Pick J, Arguiri E, Christofidou-Solomidou M, Albelda SM, Muzykantov VR. Modulation of endothelial targeting by size of antibody-antioxidant enzyme conjugates. Journal of Controlled Release : Official Journal of the Controlled Release Society. 149: 236-41. PMID 21044652 DOI: 10.1016/J.Jconrel.2010.10.026  0.495
2011 Shuvaev VV, Han J, Yu KJ, Huang S, Hawkins BJ, Madesh M, Nakada M, Muzykantov VR. PECAM-targeted delivery of SOD inhibits endothelial inflammatory response. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 348-57. PMID 20876216 DOI: 10.1096/Fj.10-169789  0.48
2011 Sebastiani AS, Hermanns MI, Muzykantov VR, Shuvaev VV, Wiewrodt R, Kirkpatrick CJ. Targeting of an antioxidative conjugate - effects on hydrogen peroxide-induced toxicity in human pulmonary microvascular endothelial cells European Journal of Anaesthesiology. 28: 75-76. DOI: 10.1097/00003643-201106001-00239  0.313
2011 Liu J, Zern B, Ayyaswamy P, Eckmann D, Muzykantov V, Radhakrishnan R. Monte Carlo Simulations of Absolute Binding Free Energy of Targeted Nanocarriers to Cell Surfaces Biophysical Journal. 100: 614a-615a. DOI: 10.1016/J.Bpj.2010.12.3539  0.407
2010 Liu J, Weller GE, Zern B, Ayyaswamy PS, Eckmann DM, Muzykantov VR, Radhakrishnan R. Computational model for nanocarrier binding to endothelium validated using in vivo, in vitro, and atomic force microscopy experiments. Proceedings of the National Academy of Sciences of the United States of America. 107: 16530-5. PMID 20823256 DOI: 10.1073/Pnas.1006611107  0.403
2010 Carnemolla R, Shuvaev VV, Muzykantov VR. Targeting antioxidant and antithrombotic biotherapeutics to endothelium. Seminars in Thrombosis and Hemostasis. 36: 332-42. PMID 20490983 DOI: 10.1055/S-0030-1253455  0.492
2010 Chorny M, Hood E, Levy RJ, Muzykantov VR. Endothelial delivery of antioxidant enzymes loaded into non-polymeric magnetic nanoparticles. Journal of Controlled Release : Official Journal of the Controlled Release Society. 146: 144-51. PMID 20483366 DOI: 10.1016/J.Jconrel.2010.05.003  0.376
2010 Zaitsev S, Spitzer D, Murciano JC, Ding BS, Tliba S, Kowalska MA, Marcos-Contreras OA, Kuo A, Stepanova V, Atkinson JP, Poncz M, Cines DB, Muzykantov VR. Sustained thromboprophylaxis mediated by an RBC-targeted pro-urokinase zymogen activated at the site of clot formation. Blood. 115: 5241-8. PMID 20410503 DOI: 10.1182/Blood-2010-01-261610  0.703
2010 Muzykantov VR. Drug delivery by red blood cells: vascular carriers designed by mother nature. Expert Opinion On Drug Delivery. 7: 403-27. PMID 20192900 DOI: 10.1517/17425241003610633  0.459
2010 Gersh KC, Zaitsev S, Muzykantov V, Cines DB, Weisel JW. The spatial dynamics of fibrin clot dissolution catalyzed by erythrocyte-bound vs. free fibrinolytics. Journal of Thrombosis and Haemostasis : Jth. 8: 1066-74. PMID 20149071 DOI: 10.1111/J.1538-7836.2010.03802.X  0.323
2010 Simone E, Dziubla T, Shuvaev V, Muzykantov VR. Synthesis and characterization of polymer nanocarriers for the targeted delivery of therapeutic enzymes. Methods in Molecular Biology (Clifton, N.J.). 610: 145-64. PMID 20013177 DOI: 10.1007/978-1-60327-029-8_9  0.811
2010 Zaitsev S, Zaitzev S, Spitzer D, Murciano JC, Ding BS, Tliba S, Kowalska MA, Bdeir K, Kuo A, Stepanova V, Atkinson JP, Poncz M, Cines DB, Muzykantov VR. Targeting of a mutant plasminogen activator to circulating red blood cells for prophylactic fibrinolysis. The Journal of Pharmacology and Experimental Therapeutics. 332: 1022-31. PMID 19952305 DOI: 10.1124/Jpet.109.159194  0.718
2010 Muzykantov VR, Balyasnikova IV, Joshi A, Fisher AB, Smirnov MD, Esmon NL, Esmon CT. Epitope-dependent selective targeting of thrombomodulin monoclonal antibodies to either surface or intracellular compartment of endothelial cells. Drug Delivery. 5: 197-206. PMID 19569985 DOI: 10.3109/10717549809052035  0.425
2010 Fuentes R, Kowalska MA, Tliba S, Bougie DW, Aster RH, Cines DB, Muzykantov VR, Poncz M, Zaitsev S. Platelet-Targeted Pro-Urokinase as a Novel Thromboprophylaxis Fibrinolytic Strategy Blood. 116: 3339-3339. DOI: 10.1182/Blood.V116.21.3339.3339  0.412
2009 Calderon AJ, Muzykantov V, Muro S, Eckmann DM. Flow dynamics, binding and detachment of spherical carriers targeted to ICAM-1 on endothelial cells Biorheology. 46: 323-341. PMID 19721193 DOI: 10.3233/Bir-2009-0544  0.518
2009 Shuvaev VV, Christofidou-Solomidou M, Bhora F, Laude K, Cai H, Dikalov S, Arguiri E, Solomides CC, Albelda SM, Harrison DG, Muzykantov VR. Targeted detoxification of selected reactive oxygen species in the vascular endothelium. The Journal of Pharmacology and Experimental Therapeutics. 331: 404-11. PMID 19692634 DOI: 10.1124/Jpet.109.156877  0.46
2009 Murciano JC, Higazi AA, Cines DB, Muzykantov VR. Soluble urokinase receptor conjugated to carrier red blood cells binds latent pro-urokinase and alters its functional profile. Journal of Controlled Release : Official Journal of the Controlled Release Society. 139: 190-6. PMID 19616049 DOI: 10.1016/J.Jconrel.2009.07.003  0.415
2009 Simone EA, Dziubla TD, Discher DE, Muzykantov VR. Filamentous polymer nanocarriers of tunable stiffness that encapsulate the therapeutic enzyme catalase. Biomacromolecules. 10: 1324-30. PMID 19385657 DOI: 10.1021/Bm900189X  0.754
2009 Ding BS, Hong N, Christofidou-Solomidou M, Gottstein C, Albelda SM, Cines DB, Fisher AB, Muzykantov VR. Anchoring fusion thrombomodulin to the endothelial lumen protects against injury-induced lung thrombosis and inflammation. American Journal of Respiratory and Critical Care Medicine. 180: 247-56. PMID 19342415 DOI: 10.1164/Rccm.200809-1433Oc  0.673
2009 Simone EA, Dziubla TD, Arguiri E, Vardon V, Shuvaev VV, Christofidou-Solomidou M, Muzykantov VR. Loading PEG-catalase into filamentous and spherical polymer nanocarriers. Pharmaceutical Research. 26: 250-60. PMID 18956141 DOI: 10.1007/S11095-008-9744-7  0.746
2009 Simone E, Ding BS, Muzykantov V. Targeted delivery of therapeutics to endothelium. Cell and Tissue Research. 335: 283-300. PMID 18815813 DOI: 10.1007/S00441-008-0676-7  0.834
2008 Simone EA, Dziubla TD, Muzykantov VR. Polymeric carriers: role of geometry in drug delivery. Expert Opinion On Drug Delivery. 5: 1283-300. PMID 19040392 DOI: 10.1517/17425240802567846  0.783
2008 Danielyan K, Ganguly K, Ding BS, Atochin D, Zaitsev S, Murciano JC, Huang PL, Kasner SE, Cines DB, Muzykantov VR. Cerebrovascular thromboprophylaxis in mice by erythrocyte-coupled tissue-type plasminogen activator. Circulation. 118: 1442-9. PMID 18794394 DOI: 10.1161/Circulationaha.107.750257  0.641
2008 Garnacho C, Albelda SM, Muzykantov VR, Muro S. Differential intra-endothelial delivery of polymer nanocarriers targeted to distinct PECAM-1 epitopes. Journal of Controlled Release : Official Journal of the Controlled Release Society. 130: 226-33. PMID 18606202 DOI: 10.1016/J.Jconrel.2008.06.007  0.507
2008 Muro S, Garnacho C, Champion JA, Leferovich J, Gajewski C, Schuchman EH, Mitragotri S, Muzykantov VR. Control of endothelial targeting and intracellular delivery of therapeutic enzymes by modulating the size and shape of ICAM-1-targeted carriers. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1450-8. PMID 18560419 DOI: 10.1038/Mt.2008.127  0.524
2008 Garnacho C, Dhami R, Simone E, Dziubla T, Leferovich J, Schuchman EH, Muzykantov V, Muro S. Delivery of acid sphingomyelinase in normal and niemann-pick disease mice using intercellular adhesion molecule-1-targeted polymer nanocarriers Journal of Pharmacology and Experimental Therapeutics. 325: 400-408. PMID 18287213 DOI: 10.1124/Jpet.107.133298  0.806
2008 Garnacho C, Shuvaev V, Thomas A, McKenna L, Sun J, Koval M, Albelda S, Muzykantov V, Muro S. RhoA activation and actin reorganization involved in endothelial CAM-mediated endocytosis of anti-PECAM carriers: critical role for tyrosine 686 in the cytoplasmic tail of PECAM-1. Blood. 111: 3024-33. PMID 18182571 DOI: 10.1182/Blood-2007-06-098657  0.52
2008 Rossin R, Muro S, Welch MJ, Muzykantov VR, Schuster DP. In vivo imaging of 64Cu-labeled polymer nanoparticles targeted to the lung endothelium. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 49: 103-11. PMID 18077519 DOI: 10.2967/Jnumed.107.045302  0.395
2008 Ding BS, Hong N, Murciano JC, Ganguly K, Gottstein C, Christofidou-Solomidou M, Albelda SM, Fisher AB, Cines DB, Muzykantov VR. Prophylactic thrombolysis by thrombin-activated latent prourokinase targeted to PECAM-1 in the pulmonary vasculature. Blood. 111: 1999-2006. PMID 18045968 DOI: 10.1182/Blood-2007-07-103002  0.714
2008 Dziubla TD, Shuvaev VV, Hong NK, Hawkins BJ, Madesh M, Takano H, Simone E, Nakada MT, Fisher A, Albelda SM, Muzykantov VR. Endothelial targeting of semi-permeable polymer nanocarriers for enzyme therapies. Biomaterials. 29: 215-27. PMID 17950837 DOI: 10.1016/J.Biomaterials.2007.09.023  0.801
2007 Simone EA, Dziubla TD, Colon-Gonzalez F, Discher DE, Muzykantov VR. Effect of polymer amphiphilicity on loading of a therapeutic enzyme into protective filamentous and spherical polymer nanocarriers. Biomacromolecules. 8: 3914-21. PMID 18038999 DOI: 10.1021/Bm700888H  0.76
2007 Shuvaev VV, Tliba S, Nakada M, Albelda SM, Muzykantov VR. Platelet-endothelial cell adhesion molecule-1-directed endothelial targeting of superoxide dismutase alleviates oxidative stress caused by either extracellular or intracellular superoxide. The Journal of Pharmacology and Experimental Therapeutics. 323: 450-7. PMID 17712041 DOI: 10.1124/Jpet.107.127126  0.465
2007 Danielyan K, Ding BS, Gottstein C, Cines DB, Muzykantov VR. Delivery of anti-platelet-endothelial cell adhesion molecule single-chain variable fragment-urokinase fusion protein to the cerebral vasculature lyses arterial clots and attenuates postischemic brain edema. The Journal of Pharmacology and Experimental Therapeutics. 321: 947-52. PMID 17389242 DOI: 10.1124/Jpet.107.120535  0.695
2007 Shuvaev VV, Christofidou-Solomidou M, Scherpereel A, Simone E, Arguiri E, Tliba S, Pick J, Kennel S, Albelda SM, Muzykantov VR. Factors modulating the delivery and effect of enzymatic cargo conjugated with antibodies targeted to the pulmonary endothelium. Journal of Controlled Release : Official Journal of the Controlled Release Society. 118: 235-44. PMID 17270308 DOI: 10.1016/J.Jconrel.2006.12.025  0.827
2007 Ganguly K, Murciano JC, Westrick R, Leferovich J, Cines DB, Muzykantov VR. The glycocalyx protects erythrocyte-bound tissue-type plasminogen activator from enzymatic inhibition. The Journal of Pharmacology and Experimental Therapeutics. 321: 158-64. PMID 17215448 DOI: 10.1124/Jpet.106.114405  0.325
2006 Dziubla TD, Muzykantov VR. Synthetic carriers for vascular delivery of protein therapeutics. Biotechnology & Genetic Engineering Reviews. 22: 267-98. PMID 18476335 DOI: 10.1080/02648725.2006.10648074  0.424
2006 Perkowski S, Scherpereel A, Murciano JC, Arguiri E, Solomides CC, Albelda SM, Muzykantov V, Christofidou-Solomidou M. Dissociation between alveolar transmigration of neutrophils and lung injury in hyperoxia. American Journal of Physiology. Lung Cellular and Molecular Physiology. 291: L1050-8. PMID 16815892 DOI: 10.1152/Ajplung.00067.2006  0.375
2006 Zaitsev S, Danielyan K, Murciano JC, Ganguly K, Krasik T, Taylor RP, Pincus S, Jones S, Cines DB, Muzykantov VR. Human complement receptor type 1-directed loading of tissue plasminogen activator on circulating erythrocytes for prophylactic fibrinolysis. Blood. 108: 1895-902. PMID 16735601 DOI: 10.1182/Blood-2005-11-012336  0.356
2006 Ding BS, Dziubla T, Shuvaev VV, Muro S, Muzykantov VR. Advanced drug delivery systems that target the vascular endothelium. Molecular Interventions. 6: 98-112. PMID 16565472 DOI: 10.1124/Mi.6.2.7  0.757
2006 Muro S, Dziubla T, Qiu W, Leferovich J, Cui X, Berk E, Muzykantov VR. Endothelial targeting of high-affinity multivalent polymer nanocarriers directed to intercellular adhesion molecule 1. The Journal of Pharmacology and Experimental Therapeutics. 317: 1161-9. PMID 16505161 DOI: 10.1124/Jpet.105.098970  0.532
2006 Christofidou-Solomidou M, Muzykantov VR. Antioxidant strategies in respiratory medicine. Treatments in Respiratory Medicine. 5: 47-78. PMID 16409015 DOI: 10.2165/00151829-200605010-00004  0.364
2006 Muro S, Mateescu M, Gajewski C, Robinson M, Muzykantov VR, Koval M. Control of intracellular trafficking of ICAM-1-targeted nanocarriers by endothelial Na+/H+ exchanger proteins. American Journal of Physiology. Lung Cellular and Molecular Physiology. 290: L809-17. PMID 16299052 DOI: 10.1152/Ajplung.00311.2005  0.498
2006 Ganguly K, Goel MS, Krasik T, Bdeir K, Diamond SL, Cines DB, Muzykantov VR, Murciano JC. Fibrin affinity of erythrocyte-coupled tissue-type plasminogen activators endures hemodynamic forces and enhances fibrinolysis in vivo. The Journal of Pharmacology and Experimental Therapeutics. 316: 1130-6. PMID 16284278 DOI: 10.1124/Jpet.105.093450  0.374
2006 Muro S, Schuchman EH, Muzykantov VR. Lysosomal enzyme delivery by ICAM-1-targeted nanocarriers bypassing glycosylation- and clathrin-dependent endocytosis. Molecular Therapy : the Journal of the American Society of Gene Therapy. 13: 135-41. PMID 16153895 DOI: 10.1016/J.Ymthe.2005.07.687  0.426
2006 Muro S, Koval M, Muzykantov V. Endothelial endocytic pathways: gates for vascular drug delivery. Current Vascular Pharmacology. 2: 281-99. PMID 15320826 DOI: 10.2174/1570161043385736  0.495
2005 Muzykantov VR. Biomedical aspects of targeted delivery of drugs to pulmonary endothelium. Expert Opinion On Drug Delivery. 2: 909-26. PMID 16296786 DOI: 10.1517/17425247.2.5.909  0.519
2005 Ding BS, Gottstein C, Grunow A, Kuo A, Ganguly K, Albelda SM, Cines DB, Muzykantov VR. Endothelial targeting of a recombinant construct fusing a PECAM-1 single-chain variable antibody fragment (scFv) with prourokinase facilitates prophylactic thrombolysis in the pulmonary vasculature. Blood. 106: 4191-8. PMID 16144802 DOI: 10.1182/Blood-2005-05-2002  0.737
2005 Dziubla TD, Karim A, Muzykantov VR. Polymer nanocarriers protecting active enzyme cargo against proteolysis. Journal of Controlled Release : Official Journal of the Controlled Release Society. 102: 427-39. PMID 15653162 DOI: 10.1016/J.Jconrel.2004.10.017  0.381
2005 Ganguly K, Krasik T, Medinilla S, Bdeir K, Cines DB, Muzykantov VR, Murciano JC. Blood clearance and activity of erythrocyte-coupled fibrinolytics. The Journal of Pharmacology and Experimental Therapeutics. 312: 1106-13. PMID 15525799 DOI: 10.1124/Jpet.104.075770  0.348
2005 Muro S, Gajewski C, Koval M, Muzykantov VR. ICAM-1 recycling in endothelial cells: a novel pathway for sustained intracellular delivery and prolonged effects of drugs. Blood. 105: 650-8. PMID 15367437 DOI: 10.1182/Blood-2004-05-1714  0.442
2005 Ganguly K, Cines DB, Muzykantov VR. Coupling Tissue Type Plasminogen Activator to Carrier Erythrocyte Protects Against Plasma Inhibitors. Blood. 106: 1881-1881. DOI: 10.1182/Blood.V106.11.1881.1881  0.346
2004 Muro S, Muzykantov VR, Murciano JC. Characterization of endothelial internalization and targeting of antibody-enzyme conjugates in cell cultures and in laboratory animals. Methods in Molecular Biology (Clifton, N.J.). 283: 21-36. PMID 15197300 DOI: 10.1385/1-59259-813-7:021  0.508
2004 Shuvaev VV, Dziubla T, Wiewrodt R, Muzykantov VR. Streptavidin-biotin crosslinking of therapeutic enzymes with carrier antibodies: nanoconjugates for protection against endothelial oxidative stress. Methods in Molecular Biology (Clifton, N.J.). 283: 3-19. PMID 15197299 DOI: 10.1385/1-59259-813-7:003  0.495
2004 Vadseth C, Souza JM, Thomson L, Seagraves A, Nagaswami C, Scheiner T, Torbet J, Vilaire G, Bennett JS, Murciano JC, Muzykantov V, Penn MS, Hazen SL, Weisel JW, Ischiropoulos H. Pro-thrombotic state induced by post-translational modification of fibrinogen by reactive nitrogen species. The Journal of Biological Chemistry. 279: 8820-6. PMID 14681238 DOI: 10.1074/Jbc.M306101200  0.304
2004 Ganguly K, Krasik T, Bdeir K, Cines DB, Muzykantov VR, Murciano J. Conjugation of Plasminogen Activators to Carrier Erythrocytes Imparts New Biological Properties to Their Soluble Counterparts. Blood. 104: 534-534. DOI: 10.1182/Blood.V104.11.534.534  0.349
2003 Muro S, Cui X, Gajewski C, Murciano JC, Muzykantov VR, Koval M. Slow intracellular trafficking of catalase nanoparticles targeted to ICAM-1 protects endothelial cells from oxidative stress. American Journal of Physiology. Cell Physiology. 285: C1339-47. PMID 12878488 DOI: 10.1152/Ajpcell.00099.2003  0.439
2003 Christofidou-Solomidou M, Scherpereel A, Wiewrodt R, Ng K, Sweitzer T, Arguiri E, Shuvaev V, Solomides CC, Albelda SM, Muzykantov VR. PECAM-directed delivery of catalase to endothelium protects against pulmonary vascular oxidative stress. American Journal of Physiology. Lung Cellular and Molecular Physiology. 285: L283-92. PMID 12851209 DOI: 10.1152/Ajplung.00021.2003  0.483
2003 Murciano JC, Medinilla S, Eslin D, Atochina E, Cines DB, Muzykantov VR. Prophylactic fibrinolysis through selective dissolution of nascent clots by tPA-carrying erythrocytes. Nature Biotechnology. 21: 891-6. PMID 12845330 DOI: 10.1038/Nbt846  0.407
2003 Sweitzer TD, Thomas AP, Wiewrodt R, Nakada MT, Branco F, Muzykantov VR. PECAM-directed immunotargeting of catalase: specific, rapid and transient protection against hydrogen peroxide. Free Radical Biology & Medicine. 34: 1035-46. PMID 12684088 DOI: 10.1016/S0891-5849(03)00029-7  0.425
2003 Kozower BD, Christofidou-Solomidou M, Sweitzer TD, Muro S, Buerk DG, Solomides CC, Albelda SM, Patterson GA, Muzykantov VR. Immunotargeting of catalase to the pulmonary endothelium alleviates oxidative stress and reduces acute lung transplantation injury. Nature Biotechnology. 21: 392-8. PMID 12652312 DOI: 10.1038/Nbt806  0.418
2003 Muro S, Wiewrodt R, Thomas A, Koniaris L, Albelda SM, Muzykantov VR, Koval M. A novel endocytic pathway induced by clustering endothelial ICAM-1 or PECAM-1. Journal of Cell Science. 116: 1599-609. PMID 12640043 DOI: 10.1242/Jcs.00367  0.432
2003 Murciano JC, Muro S, Koniaris L, Christofidou-Solomidou M, Harshaw DW, Albelda SM, Granger DN, Cines DB, Muzykantov VR. ICAM-directed vascular immunotargeting of antithrombotic agents to the endothelial luminal surface. Blood. 101: 3977-84. PMID 12531816 DOI: 10.1182/Blood-2002-09-2853  0.543
2002 Manevich Y, Sweitzer T, Pak JH, Feinstein SI, Muzykantov V, Fisher AB. 1-Cys peroxiredoxin overexpression protects cells against phospholipid peroxidation-mediated membrane damage Proceedings of the National Academy of Sciences of the United States of America. 99: 11599-11604. PMID 12193653 DOI: 10.1073/Pnas.182384499  0.306
2002 Christofidou-Solomidou M, Scherpereel A, Solomides CC, Muzykantov VR, Machtay M, Albelda SM, DiNubile MJ. Changes in plasma gelsolin concentration during acute oxidant lung injury in mice. Lung. 180: 91-104. PMID 12172902 DOI: 10.1007/S004080000084  0.325
2002 Christofidou-Solomidou M, Kennel S, Scherpereel A, Wiewrodt R, Solomides CC, Pietra GG, Murciano JC, Shah SA, Ischiropoulos H, Albelda SM, Muzykantov VR. Vascular immunotargeting of glucose oxidase to the endothelial antigens induces distinct forms of oxidant acute lung injury: targeting to thrombomodulin, but not to PECAM-1, causes pulmonary thrombosis and neutrophil transmigration. The American Journal of Pathology. 160: 1155-69. PMID 11891211 DOI: 10.1016/S0002-9440(10)64935-8  0.415
2002 Scherpereel A, Rome JJ, Wiewrodt R, Watkins SC, Harshaw DW, Alder S, Christofidou-Solomidou M, Haut E, Murciano JC, Nakada M, Albelda SM, Muzykantov VR. Platelet-endothelial cell adhesion molecule-1-directed immunotargeting to cardiopulmonary vasculature. The Journal of Pharmacology and Experimental Therapeutics. 300: 777-86. PMID 11861781 DOI: 10.1124/Jpet.300.3.777  0.423
2002 Murciano JC, Harshaw D, Neschis DG, Koniaris L, Bdeir K, Medinilla S, Fisher AB, Golden MA, Cines DB, Nakada MT, Muzykantov VR. Platelets inhibit the lysis of pulmonary microemboli. American Journal of Physiology. Lung Cellular and Molecular Physiology. 282: L529-39. PMID 11839549 DOI: 10.1152/Ajplung.00112.2001  0.334
2002 Wiewrodt R, Thomas AP, Cipelletti L, Christofidou-Solomidou M, Weitz DA, Feinstein SI, Schaffer D, Albelda SM, Koval M, Muzykantov VR. Size-dependent intracellular immunotargeting of therapeutic cargoes into endothelial cells. Blood. 99: 912-22. PMID 11806994 DOI: 10.1182/Blood.V99.3.912  0.496
2002 Murciano JC, Harshaw DW, Ghitescu L, Danilov SM, Muzykantov VR. Vascular immunotargeting to endothelial surface in a specific macrodomain in alveolar capillaries. American Journal of Respiratory and Critical Care Medicine. 164: 1295-302. PMID 11673225 DOI: 10.1164/Ajrccm.164.7.2010076  0.422
2001 Danilov SM, Gavrilyuk VD, Franke FE, Pauls K, Harshaw DW, McDonald TD, Miletich DJ, Muzykantov VR. Lung uptake of antibodies to endothelial antigens: key determinants of vascular immunotargeting. American Journal of Physiology. Lung Cellular and Molecular Physiology. 280: L1335-47. PMID 11350815 DOI: 10.1152/Ajplung.2001.280.6.L1335  0.445
2001 Manevich Y, Al-Mehdi A, Muzykantov V, Fisher AB. Oxidative burst and NO generation as initial response to ischemia in flow-adapted endothelial cells. American Journal of Physiology. Heart and Circulatory Physiology. 280: H2126-35. PMID 11299214 DOI: 10.1152/Ajpheart.2001.280.5.H2126  0.306
2001 Muzykantov VR. Delivery of antioxidant enzyme proteins to the lung. Antioxidants & Redox Signaling. 3: 39-62. PMID 11291598 DOI: 10.1089/152308601750100489  0.483
2001 Muzykantov VR. Targeting of superoxide dismutase and catalase to vascular endothelium. Journal of Controlled Release : Official Journal of the Controlled Release Society. 71: 1-21. PMID 11245904 DOI: 10.1016/S0168-3659(01)00215-2  0.526
2001 Scherpereel A, Wiewrodt R, Christofidou-Solomidou M, Gervais R, Murciano JC, Albelda SM, Muzykantov VR. Cell-selective intracellular delivery of a foreign enzyme to endothelium in vivo using vascular immunotargeting. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 416-26. PMID 11156957 DOI: 10.1096/Fj.00-0022Com  0.436
2000 Christofidou-Solomidou M, Pietra GG, Solomides CC, Arguiris E, Harshaw D, Fitzgerald GA, Albelda SM, Muzykantov VR. Immunotargeting of glucose oxidase to endothelium in vivo causes oxidative vascular injury in the lungs. American Journal of Physiology. Lung Cellular and Molecular Physiology. 278: L794-805. PMID 10749757 DOI: 10.1152/Ajplung.2000.278.4.L794  0.448
2000 Bdeir K, Murciano J, Tomaszewski J, Koniaris L, Martinez J, Cines DB, Muzykantov VR, Higazi AA. Urokinase mediates fibrinolysis in the pulmonary microvasculature Blood. 96: 1820-1826. DOI: 10.1182/Blood.V96.5.1820.H8001820_1820_1826  0.358
1999 Wei Z, Costa K, Al-Mehdi AB, Dodia C, Muzykantov V, Fisher AB. Simulated ischemia in flow-adapted endothelial cells leads to generation of reactive oxygen species and cell signaling. Circulation Research. 85: 682-9. PMID 10521241 DOI: 10.1161/01.Res.85.8.682  0.325
1999 Gow AJ, Branco F, Christofidou-Solomidou M, Black-Schultz L, Albelda SM, Muzykantov VR. Immunotargeting of glucose oxidase: intracellular production of H(2)O(2) and endothelial oxidative stress. The American Journal of Physiology. 277: L271-81. PMID 10444521 DOI: 10.1152/Ajplung.1999.277.2.L271  0.351
1999 Fisher AB, Al-Mehdi AB, Muzykantov V. Activation of endothelial NADPH oxidase as the source of a reactive oxygen species in lung ischemia. Chest. 116: 25S-26S. PMID 10424568 DOI: 10.1378/Chest.116.Suppl_1.25S  0.32
1999 Muzykantov VR, Christofidou-Solomidou M, Balyasnikova I, Harshaw DW, Schultz L, Fisher AB, Albelda SM. Streptavidin facilitates internalization and pulmonary targeting of an anti-endothelial cell antibody (platelet-endothelial cell adhesion molecule 1): a strategy for vascular immunotargeting of drugs. Proceedings of the National Academy of Sciences of the United States of America. 96: 2379-84. PMID 10051650 DOI: 10.1073/Pnas.96.5.2379  0.514
1998 Atochina EN, Balyasnikova IV, Danilov SM, Granger DN, Fisher AB, Muzykantov VR. Immunotargeting of catalase to ACE or ICAM-1 protects perfused rat lungs against oxidative stress. American Journal of Physiology. Lung Cellular and Molecular Physiology. 275: L806-L817. PMID 29585636 DOI: 10.1152/Ajplung.1998.275.4.L806  0.313
1998 Al-Mehdi AB, Zhao G, Dodia C, Tozawa K, Costa K, Muzykantov V, Ross C, Blecha F, Dinauer M, Fisher AB. Endothelial NADPH oxidase as the source of oxidants in lungs exposed to ischemia or high K+ Circulation Research. 83: 730-737. PMID 9758643 DOI: 10.1161/01.Res.83.7.730  0.326
1998 Balyasnikova IV, Danilov SM, Muzykantov VR, Fisher AB. Modulation of angiotensin-converting enzyme in cultured human vascular endothelial cells. In Vitro Cellular & Developmental Biology. Animal. 34: 545-54. PMID 9719414 DOI: 10.1007/S11626-998-0114-X  0.332
1998 Muzykantov VR. Immunotargeting of drugs to the pulmonary vascular endothelium as a therapeutic strategy Pathophysiology. 5: 15-33. DOI: 10.1016/S0928-4680(98)00006-6  0.409
1997 Atochina EN, Muzykantov VR, Al-Mehdi AB, Danilov SM, Fisher AB. Normoxic lung ischemia/reperfusion accelerates shedding of angiotensin converting enzyme from the pulmonary endothelium. American Journal of Respiratory and Critical Care Medicine. 156: 1114-9. PMID 9351610 DOI: 10.1164/Ajrccm.156.4.96-12116  0.327
1997 Komatsu S, Panés J, Russell JM, Anderson DC, Muzykantov VR, Miyasaka M, Granger DN. Effects of chronic arterial hypertension on constitutive and induced intercellular adhesion molecule-1 expression in vivo. Hypertension. 29: 683-9. PMID 9040457 DOI: 10.1161/01.Hyp.29.2.683  0.359
1997 Muzykantov VR, Murciano JC, Taylor RP, Atochina EN, Herraez A. Regulation of the complement-mediated elimination of red blood cells modified with biotin and streptavidin. Analytical Biochemistry. 241: 109-19. PMID 8921172 DOI: 10.1006/Abio.1996.0384  0.312
1997 Muzykantov VR. Conjugation of catalase to a carrier antibody via a streptavidinŐbiotin cross‐linker Biotechnology and Applied Biochemistry. 26: 103-109. DOI: 10.1111/J.1470-8744.1997.Tb00454.X  0.332
1996 Muzykantov VR, Atochina EN, Kuo A, Barnathan ES, Notarfrancesco K, Shuman H, Dodia C, Fisher AB. Endothelial cells internalize monoclonal antibody to angiotensin-converting enzyme. The American Journal of Physiology. 270: L704-13. PMID 8967503 DOI: 10.1152/Ajplung.1996.270.5.L704  0.38
1996 Muzykantov VR, Atochina EN, Ischiropoulos H, Danilov SM, Fisher AB. Immunotargeting of antioxidant enzymes to the pulmonary endothelium Proceedings of the National Academy of Sciences of the United States of America. 93: 5213-5218. PMID 8643555 DOI: 10.1073/Pnas.93.11.5213  0.349
1996 Muzykantov VR, Zaltsman AB, Smirnov MD, Samokhin GP, Morgan BP. Target-sensitive immunoerythrocytes: interaction of biotinylated red blood cells with immobilized avidin induces their lysis by complement. Biochimica Et Biophysica Acta. 1279: 137-43. PMID 8603079 DOI: 10.1016/0005-2736(95)00260-X  0.391
1995 Muzykantov VR, Gavriluk VD, Reinecke A, Atochina EN, Kuo A, Barnathan ES, Fisher AB. The functional effects of biotinylation of anti-angiotensin-converting enzyme monoclonal antibody in terms of targeting in vivo. Analytical Biochemistry. 226: 279-87. PMID 7793629 DOI: 10.1006/Abio.1995.1226  0.321
1995 Muzykantov VR, Taylor RP. Attachment of biotinylated antibody to red blood cells: antigen-binding capacity of immunoerythrocytes and their susceptibility to lysis by complement. Analytical Biochemistry. 223: 142-8. PMID 7695090 DOI: 10.1006/Abio.1994.1559  0.316
1995 Zaltzman AB, Van den Berg CW, Muzykantov VR, Morgan BP. Enhanced complement susceptibility of avidin-biotin-treated human erythrocytes is a consequence of neutralization of the complement regulators CD59 and decay accelerating factor. The Biochemical Journal. 651-6. PMID 7537958 DOI: 10.1042/Bj3070651  0.318
1994 Puchnina-Artushenko EA, Ledenev AV, Ruuge EK, Muzykantov VR. Sublethal doses of exogenous hydrogen peroxide prime human neutrophils to formyl peptide. Agents and Actions. C192-4. PMID 8273565 DOI: 10.1007/Bf01972763  0.328
1993 Muzykantov VR, Smirnov MD, Zaltzman AB, Samokhin GP. Tannin-mediated attachment of avidin provides complement-resistant immunoerythrocytes that can be lysed in the presence of activator of complement. Analytical Biochemistry. 208: 338-42. PMID 8452230 DOI: 10.1006/Abio.1993.1057  0.387
1993 Muzykantov VR, Smirnov MD, Klibanov AL. Avidin attachment to biotinylated amino groups of the erythrocyte membrane eliminates homologous restriction of both classical and alternative pathways of the complement. Febs Letters. 318: 108-12. PMID 8440366 DOI: 10.1016/0014-5793(93)80002-C  0.341
1993 Muzykantov VR, Smirnov MD, Klibanov AL. Avidin attachment to red blood cells via a phospholipid derivative of biotin provides complement-resistant immunoerythrocytes. Journal of Immunological Methods. 158: 183-90. PMID 8429223 DOI: 10.1016/0022-1759(93)90212-P  0.426
1993 Hiemisch H, Gavrilyuk V, Atochina E, Slinkin M, Torchilin V, Muzykantov V, Danilov S. Purification of radiolabeled monoclonal antibodies to angiotensin-converting enzyme significantly improves specificity and efficacy of its targeting into the lung. Nuclear Medicine and Biology. 20: 435-41. PMID 8389221 DOI: 10.1016/0969-8051(93)90074-5  0.354
1993 Muzykantov VR, Zalzman AB, Fuki IV, Smirnov MD, Samokhin GP, Romanov YA. Interaction of avidin-carrying red blood cells with nucleated cells. Biochimica Et Biophysica Acta. 1179: 148-56. PMID 8218357 DOI: 10.1016/0167-4889(93)90136-D  0.36
1992 Muzykantov VR, Smirnov MD, Samokhin GP. Avidin-induced lysis of biotinylated erythrocytes by homologous complement via the alternative pathway depends on avidin's ability of multipoint binding with biotinylated membrane. Biochimica Et Biophysica Acta. 1107: 119-25. PMID 1616915 DOI: 10.1016/0005-2736(92)90336-K  0.358
1992 Atochina EN, Hiemisch HH, Muzykantov VR, Danilov SM. Systemic administration of platelet-activating factor in rat reduces specific pulmonary uptake of circulating monoclonal antibody to angiotensin-converting enzyme. Lung. 170: 349-58. PMID 1331624 DOI: 10.1007/Bf00177581  0.364
1992 Muzykantov V, Seregina N, Smirnov M. Fast Lysis by Complement and Uptake by Liver of Avidin-Carrying Biotinylated Erythrocytes The International Journal of Artificial Organs. 15: 622-627. DOI: 10.1177/039139889201501010  0.334
1991 Muzykantov VR, Smirnov MD, Samokhin GP. Streptavidin-induced lysis of homologous biotinylated erythrocytes. Evidence against the key role of the avidin charge in complement activation via the alternative pathway. Febs Letters. 280: 112-4. PMID 2009954 DOI: 10.1016/0014-5793(91)80216-P  0.316
1991 Muzykantov VR, Smirnov MD, Samokhin GP. Avidin acylation prevents the complement-dependent lysis of avidin-carrying erythrocytes. The Biochemical Journal. 393-7. PMID 1991038 DOI: 10.1042/Bj2730393  0.363
1991 Muzykantov VR, Danilov SM. Glucose oxidase conjugated with anti-endothelial monoclonal antibodies: in vitro and in vivo studies. International Journal of Radiation Biology. 60: 11-5. PMID 1677957 DOI: 10.1080/09553009114551411  0.441
1991 Muzykantov V, Smirnov M, Samokhin G. Avidin attachment to biotinylated erythrocytes induces homologous lysis via the alternative pathway of complement Blood. 78: 2611-2618. DOI: 10.1182/Blood.V78.10.2611.Bloodjournal78102611  0.321
1991 Muzykantov VR, Danilov SM. Radiolabeled monoclonal antibody to angiotensin-converting enzyme recognizes the leukocyte-mediated changes in the pulmonary endothelium International Journal of Immunopharmacology. 13: 792. DOI: 10.1016/0192-0561(91)90346-9  0.345
1990 Muzykantov VR, Trubetskaya OV, Puchnina EA, Sakharov DV, Domogatsky SP. Cytotoxicity of glucose oxidase conjugated with antibodies to target cells: killing efficiency depends on the conjugate internalization. Biochimica Et Biophysica Acta. 1053: 27-31. PMID 2364115 DOI: 10.1016/0167-4889(90)90021-5  0.451
1989 Danilov S, Sakharov I, Martynov A, Faerman A, Muzykantov V, Klibanov A, Trakht I. Monoclonal antibodies to angiotensin-converting enzyme: a powerful tool for lung and vessel studies. Journal of Molecular and Cellular Cardiology. 165-70. PMID 2543825 DOI: 10.1016/0022-2828(89)90853-5  0.4
1989 Muzykantov VR, Martynov AV, Puchnina EA, Danilov SM. In vivo administration of glucose oxidase conjugated with monoclonal antibodies to angiotensin-converting enzyme. The tissue distribution, blood clearance, and targeting into rat lungs. The American Review of Respiratory Disease. 139: 1464-73. PMID 2543247 DOI: 10.1164/Ajrccm/139.6.1464  0.44
1989 Muzykantov VR, Peclo MM. Local tissue injury induced by glucose oxidase conjugated with anti-collagen antibody. Journal of Immunological Methods. 119: 65-73. PMID 2468717 DOI: 10.1016/0022-1759(89)90382-7  0.372
1988 Idelson GL, Muzykantov VR, Chekneva EE, Shnyra AA, Shekhonin BV, Domogatsky SP. In vivo administration of antibodies against type I collagen in rat: the specific accumulation in spleen. Collagen and Related Research. 7: 383-97. PMID 3328669 DOI: 10.1016/S0174-173X(87)80037-7  0.338
1988 Muzykantov VR, Sakharov DV, Sinitsyn VV, Domogatsky SP, Goncharov NV, Danilov SM. Specific killing of human endothelial cells by antibody-conjugated glucose oxidase. Analytical Biochemistry. 169: 383-9. PMID 3260084 DOI: 10.1016/0003-2697(88)90300-4  0.431
1987 Sakharov DV, Muzykantov VR, Domogatsky SP, Danilov SM. Protection of cultured endothelial cells from hydrogen peroxide-induced injury by antibody-conjugated catalase. Biochimica Et Biophysica Acta. 930: 140-4. PMID 3620513 DOI: 10.1016/0167-4889(87)90025-5  0.461
1986 Klibanov AL, Muzykantov VR, Ivanov NN, Torchilin VP. Evaluation of quantitative parameters of the interaction of antibody-bearing liposomes with target antigens. Analytical Biochemistry. 150: 251-7. PMID 4091252 DOI: 10.1016/0003-2697(85)90507-X  0.404
1986 Glukhova MA, Domogatsky SP, Kabakov AE, Muzykantov VR, Ornatsky OI, Sakharov DV, Frid MG, Smirnov VN. Red blood cell targeting to smooth muscle cells. Febs Letters. 198: 155-8. PMID 3956726 DOI: 10.1016/0014-5793(86)81203-0  0.416
1986 Muzykantov VR, Sakharov DV, Smirnov MD, Samokhin GP, Smirnov VN. Immunotargeting of erythrocyte-bound streptokinase provides local lysis of a fibrin clot. Biochimica Et Biophysica Acta. 884: 355-62. PMID 3768424 DOI: 10.1016/0304-4165(86)90184-4  0.406
1986 Smirnov VN, Domogatsky SP, Dolgov VV, Hvatov VB, Klibanov AL, Koteliansky VE, Muzykantov VR, Repin VS, Samokhin GP, Shekhonin BV. Carrier-directed targeting of liposomes and erythrocytes to denuded areas of vessel wall. Proceedings of the National Academy of Sciences of the United States of America. 83: 6603-7. PMID 3462715 DOI: 10.1073/Pnas.83.17.6603  0.406
1986 Glukhova MA, Domogatskii SP, Kabakov AE, Muzykantov VR, Ornatskaya OI, Sakharov DV, Frid MG. Red blood cell targeting to human aortic smooth muscle cells Bulletin of Experimental Biology and Medicine. 102: 1550-1552. DOI: 10.1007/Bf00854687  0.328
1985 Muzykantov VR, Sakharov DV, Smirnov MD, Domogatsky SP, Samokhin GP. Targeting of enzyme immobilized on erythrocyte membrane to collagen-coated surface. Febs Letters. 182: 62-6. PMID 3972125 DOI: 10.1016/0014-5793(85)81154-6  0.426
1983 Samokhin GP, Smirnov MD, Muzykantov VR, Domogatsky SP, Smirnov VN. Red blood cell targeting to collagen-coated surfaces. Febs Letters. 154: 257-61. PMID 6832367 DOI: 10.1016/0014-5793(83)80160-4  0.404
1983 Smirnov MD, Samokhin GP, Muzykantov VR, Idelson GL, Domogatsky SP, Smirnov VN. Type I and III collagens as a possible target for drug delivery to the injured sites of vascular bed. Biochemical and Biophysical Research Communications. 116: 99-105. PMID 6196029 DOI: 10.1016/0006-291X(83)90386-8  0.455
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