Year |
Citation |
Score |
2019 |
Mnatsakanyan N, Llaguno MC, Yang Y, Yan Y, Weber J, Sigworth FJ, Jonas EA. A mitochondrial megachannel resides in monomeric FF ATP synthase. Nature Communications. 10: 5823. PMID 31862883 DOI: 10.1038/S41467-019-13766-2 |
0.357 |
|
2019 |
Toombes G, Jiang Y, Sigworth F. Decision letter: Cryo-EM structure of the KvAP channel reveals a non-domain-swapped voltage sensor topology Elife. DOI: 10.7554/Elife.52164.Sa1 |
0.37 |
|
2019 |
Sigworth F, Trimmer JS. Decision letter: The mechanosensitive ion channel TRAAK is localized to the mammalian node of Ranvier Elife. DOI: 10.7554/Elife.50403.021 |
0.343 |
|
2019 |
Shigematsu H, Yang Y, Yan Y, Sigworth FJ. Cryo-EM Imaging of Kv1.2 Channels with Membrane Potential Applied Biophysical Journal. 116. DOI: 10.1016/J.Bpj.2018.11.3098 |
0.471 |
|
2017 |
Bai JP, Moeini-Naghani I, Zhong S, Li FY, Bian S, Sigworth FJ, Santos-Sacchi J, Navaratnam D. Current carried by the Slc26 family member prestin does not flow through the transporter pathway. Scientific Reports. 7: 46619. PMID 28422190 DOI: 10.1038/Srep46619 |
0.352 |
|
2017 |
Shigematsu H, Yang Y, Yan Y, Chen Y, Sigworth FJ. Cryo-EM Structure of KV1.2 Channels in Liposomes Biophysical Journal. 112. DOI: 10.1016/J.Bpj.2016.11.3101 |
0.476 |
|
2016 |
Jensen KH, Brandt SS, Shigematsu H, Sigworth FJ. Statistical Modeling and Removal of Lipid Membrane Projections for Cryo-EM Structure Determination of Reconstituted Membrane Proteins. Journal of Structural Biology. PMID 26835990 DOI: 10.1016/J.Jsb.2016.01.012 |
0.375 |
|
2015 |
Sigworth FJ. Principles of cryo-EM single-particle image processing. Microscopy (Oxford, England). PMID 26705325 DOI: 10.1093/Jmicro/Dfv370 |
0.302 |
|
2015 |
Jensen KH, Sigworth F, Brandt SS. Removal of Vesicle Structures from Transmission Electron Microscope Images. Ieee Transactions On Image Processing : a Publication of the Ieee Signal Processing Society. PMID 26642456 DOI: 10.1109/Tip.2015.2504901 |
0.307 |
|
2015 |
Shigematsu H, Sigworth F, Shirouzu M. C3-O-04 * Functional structures of ion channels in lipid environment Journal of Electron Microscopy. 64. DOI: 10.1093/Jmicro/Dfv191 |
0.36 |
|
2014 |
Liu Y, Sigworth FJ. Automatic cryo-EM particle selection for membrane proteins in spherical liposomes. Journal of Structural Biology. 185: 295-302. PMID 24468290 DOI: 10.1016/J.Jsb.2014.01.004 |
0.322 |
|
2013 |
Miranda P, Contreras JE, Plested AJ, Sigworth FJ, Holmgren M, Giraldez T. State-dependent FRET reports calcium- and voltage-dependent gating-ring motions in BK channels. Proceedings of the National Academy of Sciences of the United States of America. 110: 5217-22. PMID 23479636 DOI: 10.1073/Pnas.1219611110 |
0.454 |
|
2012 |
Yan Y, Yang Y, Bian S, Sigworth FJ. Expression, purification and functional reconstitution of slack sodium-activated potassium channels. The Journal of Membrane Biology. 245: 667-74. PMID 22729647 DOI: 10.1007/S00232-012-9425-7 |
0.486 |
|
2012 |
Miranda P, Contreras JE, Wesch D, Sigworth FJ, Holmgren M, Giraldez T. State-Dependent FRET Reports Large Gating-Ring Motions in BK Channels Biophysical Journal. 102: 687a. DOI: 10.1016/J.Bpj.2011.11.3735 |
0.461 |
|
2012 |
Yang Y, Yan Y, Sigworth FJ. Slack Channels are Sensitive to External Sodium Biophysical Journal. 102. DOI: 10.1016/J.Bpj.2011.11.3696 |
0.438 |
|
2012 |
Chen Y, Shigematsu H, Nagayama K, Sigworth FJ. Measuring Membrane Potentials with Cryo-EM? Biophysical Journal. 102. DOI: 10.1016/J.Bpj.2011.11.2158 |
0.316 |
|
2011 |
Bian S, Bai JP, Chapin H, Le Moellic C, Dong H, Caplan M, Sigworth FJ, Navaratnam DS. Interactions between β-catenin and the HSlo potassium channel regulates HSlo surface expression. Plos One. 6: e28264. PMID 22194818 DOI: 10.1371/Journal.Pone.0028264 |
0.328 |
|
2011 |
Ye M, Hong J, Zhou M, Huang L, Shao X, Yang Y, Sigworth FJ, Chi C, Lin D, Wang C. A novel conotoxin, qc16a, with a unique cysteine framework and folding. Peptides. 32: 1159-65. PMID 21524672 DOI: 10.1016/J.Peptides.2011.04.008 |
0.416 |
|
2011 |
Goldstein B, Choe K, Sigworth FJ, Culurciello E. A four-channel integrated patch-clamp amplifier with current-clamp capability Midwest Symposium On Circuits and Systems. DOI: 10.1109/MWSCAS.2011.6026393 |
0.35 |
|
2011 |
Zhang Y, Yan Y, Yang Y, Sigworth F. Expression and Purification of the BK Channel Alpha-Beta1 Complex Biophysical Journal. 100. DOI: 10.1016/J.Bpj.2010.12.2311 |
0.33 |
|
2011 |
Miranda P, Contreras J, Wesch DL, Sigworth FJ, Holmgren M, Giraldez T. Calcium Induces Structural Rearrangements of the Gating Ring of the Human BK Channel Biophysical Journal. 100: 260a. DOI: 10.1016/J.Bpj.2010.12.1636 |
0.46 |
|
2010 |
Wang L, Sigworth FJ. Liposomes on a streptavidin crystal: a system to study membrane proteins by cryo-EM. Methods in Enzymology. 481: 147-64. PMID 20887857 DOI: 10.1016/S0076-6879(10)81007-9 |
0.506 |
|
2010 |
Weerakoon P, Culurciello E, Yang Y, Santos-Sacchi J, Kindlmann PJ, Sigworth FJ. Patch-clamp amplifiers on a chip. Journal of Neuroscience Methods. 192: 187-92. PMID 20637803 DOI: 10.1016/J.Jneumeth.2010.06.030 |
0.431 |
|
2010 |
Brown MR, Kronengold J, Gazula VR, Chen Y, Strumbos JG, Sigworth FJ, Navaratnam D, Kaczmarek LK. Fragile X mental retardation protein controls gating of the sodium-activated potassium channel Slack. Nature Neuroscience. 13: 819-21. PMID 20512134 DOI: 10.1038/Nn.2563 |
0.376 |
|
2010 |
Barmeyer C, Rahner C, Yang Y, Sigworth FJ, Binder HJ, Rajendran VM. Cloning and identification of tissue-specific expression of KCNN4 splice variants in rat colon. American Journal of Physiology. Cell Physiology. 299: C251-63. PMID 20445171 DOI: 10.1152/Ajpcell.00091.2009 |
0.405 |
|
2010 |
Singer A, Coifman RR, Sigworth FJ, Chester DW, Shkolnisky Y. Detecting consistent common lines in cryo-EM by voting. Journal of Structural Biology. 169: 312-22. PMID 19925867 DOI: 10.1016/J.Jsb.2009.11.003 |
0.305 |
|
2010 |
Weerakoon P, Culurciello E, Santos-Sacchi J, Yang Y, Sigworth F. A Two-Channel Patch-Clamp System on a Chip Biophysical Journal. 98: 603a. DOI: 10.1016/J.Bpj.2009.12.3288 |
0.439 |
|
2010 |
Fleming MR, Kronengold J, Yan Y, Lam TT, Gulcicek E, Sigworth FJ, Nairn AC, Kaczmarek LK. Identification of Regulatory Phosphorylation Sites in Slack and Slick Sodium Activated Potassium (KNa) Channels Biophysical Journal. 98: 316a. DOI: 10.1016/J.Bpj.2009.12.1714 |
0.367 |
|
2009 |
Weerakoon P, Culurciello E, Klemic KG, Sigworth FJ. An integrated patch-clamp potentiostat with electrode compensation. Ieee Transactions On Biomedical Circuits and Systems. 3: 117-25. PMID 23853203 DOI: 10.1109/Tbcas.2008.2005419 |
0.306 |
|
2009 |
Wang L, Sigworth FJ. Structure of the BK potassium channel in a lipid membrane from electron cryomicroscopy. Nature. 461: 292-5. PMID 19718020 DOI: 10.1038/Nature08291 |
0.597 |
|
2009 |
Chen H, Kronengold J, Yan Y, Gazula VR, Brown MR, Ma L, Ferreira G, Yang Y, Bhattacharjee A, Sigworth FJ, Salkoff L, Kaczmarek LK. The N-terminal domain of Slack determines the formation and trafficking of Slick/Slack heteromeric sodium-activated potassium channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 5654-65. PMID 19403831 DOI: 10.1523/Jneurosci.5978-08.2009 |
0.445 |
|
2009 |
Yang Y, Yan Y, Sigworth FJ. Functional Tests Of Purified Slack Channel Protein For Cryo-em Structure Determination Biophysical Journal. 96. DOI: 10.1016/J.Bpj.2008.12.2108 |
0.463 |
|
2009 |
Wang L, Sigworth F. Cryo-EM Structure of Functional BK Channels in Lipid Bilayers Biophysical Journal. 96: 413. DOI: 10.1016/J.Bpj.2008.12.2107 |
0.602 |
|
2008 |
Wang L, Ounjai P, Sigworth FJ. Streptavidin crystals as nanostructured supports and image-calibration references for cryo-EM data collection. Journal of Structural Biology. 164: 190-8. PMID 18707004 DOI: 10.1016/J.Jsb.2008.07.008 |
0.49 |
|
2008 |
Weerakoon P, Sigworth F, Culurciello E. Integrated patch-clamp biosensor for high-density screening of cell conductance Electronics Letters. 44: 81-82. DOI: 10.1049/El:20083151 |
0.315 |
|
2007 |
Sigworth FJ. The last few frames of the voltage-gating movie. Biophysical Journal. 93: 2981-3. PMID 17704178 DOI: 10.1529/Biophysj.107.115741 |
0.457 |
|
2007 |
Ounjai P, Unger VM, Sigworth FJ, Angsuthanasombat C. Two conformational states of the membrane-associated Bacillus thuringiensis Cry4Ba delta-endotoxin complex revealed by electron crystallography: implications for toxin-pore formation. Biochemical and Biophysical Research Communications. 361: 890-5. PMID 17681273 DOI: 10.1016/J.Bbrc.2007.07.086 |
0.324 |
|
2006 |
Wang L, Bose PS, Sigworth FJ. Using cryo-EM to measure the dipole potential of a lipid membrane. Proceedings of the National Academy of Sciences of the United States of America. 103: 18528-33. PMID 17116859 DOI: 10.1073/Pnas.0608714103 |
0.498 |
|
2006 |
Yang B, Gribkoff VK, Pan J, Damagnez V, Dworetzky SI, Boissard CG, Bhattacharjee A, Yan Y, Sigworth FJ, Kaczmarek LK. Pharmacological activation and inhibition of Slack (Slo2.2) channels. Neuropharmacology. 51: 896-906. PMID 16876206 DOI: 10.1016/J.Neuropharm.2006.06.003 |
0.484 |
|
2006 |
Li X, Klemic KG, Reed MA, Sigworth FJ. Microfluidic system for planar patch clamp electrode arrays. Nano Letters. 6: 815-9. PMID 16608289 DOI: 10.1021/Nl060165R |
0.317 |
|
2006 |
Wang L, Sigworth FJ. Cryo-EM and single particles. Physiology (Bethesda, Md.). 21: 13-8. PMID 16443818 DOI: 10.1152/Physiol.00045.2005 |
0.501 |
|
2006 |
Zhang P, Sigworth FJ, Canessa CM. Gating of acid-sensitive ion channel-1: release of Ca2+ block vs. allosteric mechanism. The Journal of General Physiology. 127: 109-17. PMID 16418400 DOI: 10.1085/Jgp.200509396 |
0.452 |
|
2005 |
Giraldez T, Hughes TE, Sigworth FJ. Generation of functional fluorescent BK channels by random insertion of GFP variants. The Journal of General Physiology. 126: 429-38. PMID 16260837 DOI: 10.1085/Jgp.200509368 |
0.428 |
|
2005 |
Sigworth FJ, Klemic KG. Microchip technology in ion-channel research. Ieee Transactions On Nanobioscience. 4: 121-7. PMID 15816178 DOI: 10.1109/Tnb.2004.842471 |
0.399 |
|
2005 |
Klemic KG, Klemic JF, Sigworth FJ. An air-molding technique for fabricating PDMS planar patch-clamp electrodes. Pflã¼Gers Archiv : European Journal of Physiology. 449: 564-72. PMID 15578213 DOI: 10.1007/S00424-004-1360-8 |
0.324 |
|
2004 |
Yang Y, Yan Y, Sigworth FJ. Can Shaker potassium channels be locked in the deactivated state? The Journal of General Physiology. 124: 163-71. PMID 15277577 DOI: 10.1085/Jgp.200409057 |
0.437 |
|
2003 |
Bhattacharjee A, Joiner WJ, Wu M, Yang Y, Sigworth FJ, Kaczmarek LK. Slick (Slo2.1), a rapidly-gating sodium-activated potassium channel inhibited by ATP. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 11681-91. PMID 14684870 DOI: 10.1523/Jneurosci.23-37-11681.2003 |
0.441 |
|
2003 |
Sigworth FJ. Structural biology: Life's transistors. Nature. 423: 21-2. PMID 12721605 DOI: 10.1038/423021A |
0.431 |
|
2002 |
Jiang QX, Thrower EC, Chester DW, Ehrlich BE, Sigworth FJ. Three-dimensional structure of the type 1 inositol 1,4,5-trisphosphate receptor at 24 A resolution. The Embo Journal. 21: 3575-81. PMID 12110570 DOI: 10.1093/Emboj/Cdf380 |
0.351 |
|
2002 |
Sigworth FJ, Klemic KG. Patch clamp on a chip. Biophysical Journal. 82: 2831-2. PMID 12023207 DOI: 10.1016/S0006-3495(02)75625-7 |
0.333 |
|
2002 |
Klemic KG, Klemic JF, Reed MA, Sigworth FJ. Micromolded PDMS planar electrode allows patch clamp electrical recordings from cells. Biosensors & Bioelectronics. 17: 597-604. PMID 11959483 DOI: 10.1016/S0956-5663(02)00015-5 |
0.308 |
|
2002 |
Venkataramanan L, Sigworth FJ. Applying hidden Markov models to the analysis of single ion channel activity. Biophysical Journal. 82: 1930-42. PMID 11916851 DOI: 10.1016/S0006-3495(02)75542-2 |
0.403 |
|
2001 |
Sigworth FJ. Potassium channel mechanics. Neuron. 32: 555-6. PMID 11719196 DOI: 10.1016/S0896-6273(01)00509-8 |
0.465 |
|
2001 |
Zheng J, Vankataramanan L, Sigworth FJ. Hidden Markov model analysis of intermediate gating steps associated with the pore gate of shaker potassium channels. The Journal of General Physiology. 118: 547-64. PMID 11696611 DOI: 10.1085/Jgp.118.5.547 |
0.488 |
|
2001 |
Jiang QX, Chester DW, Sigworth FJ. Spherical reconstruction: a method for structure determination of membrane proteins from cryo-EM images. Journal of Structural Biology. 133: 119-31. PMID 11472084 DOI: 10.1006/Jsbi.2001.4376 |
0.349 |
|
2001 |
Islas LD, Sigworth FJ. Electrostatics and the gating pore of Shaker potassium channels. The Journal of General Physiology. 117: 69-89. PMID 11134232 DOI: 10.1085/Jgp.117.1.69 |
0.391 |
|
2000 |
Venkataramanan L, Kuc R, Sigworth FJ. Identification of hidden markov models for ion channel currents-part iii: bandlimited, sampled data Ieee Transactions On Signal Processing. 48: 376-385. DOI: 10.1109/78.823965 |
0.337 |
|
1999 |
Islas LD, Sigworth FJ. Voltage sensitivity and gating charge in Shaker and Shab family potassium channels. The Journal of General Physiology. 114: 723-42. PMID 10539976 DOI: 10.1085/Jgp.114.5.723 |
0.431 |
|
1999 |
Baumgartner W, Islas L, Sigworth FJ. Two-microelectrode voltage clamp of Xenopus oocytes: voltage errors and compensation for local current flow. Biophysical Journal. 77: 1980-91. PMID 10512818 DOI: 10.1016/S0006-3495(99)77039-6 |
0.398 |
|
1999 |
Andersen OS, Apell HJ, Bamberg E, Busath DD, Koeppe RE, Sigworth FJ, Szabo G, Urry DW, Woolley A. Gramicidin channel controversy--the structure in a lipid environment. Nature Structural Biology. 6: 609; discussion 611-. PMID 10404209 DOI: 10.1038/10648 |
0.452 |
|
1998 |
Yang Y, Sigworth FJ. Single-channel properties of IKs potassium channels. The Journal of General Physiology. 112: 665-78. PMID 9834139 DOI: 10.1085/Jgp.112.6.665 |
0.495 |
|
1998 |
Sigworth FJ. A maximum-likelihood approach to single-particle image refinement. Journal of Structural Biology. 122: 328-39. PMID 9774537 DOI: 10.1006/Jsbi.1998.4014 |
0.321 |
|
1998 |
Zheng J, Sigworth FJ. Intermediate conductances during deactivation of heteromultimeric Shaker potassium channels. The Journal of General Physiology. 112: 457-74. PMID 9758864 DOI: 10.1085/Jgp.112.4.457 |
0.476 |
|
1998 |
Schoppa NE, Sigworth FJ. Activation of Shaker potassium channels. III. An activation gating model for wild-type and V2 mutant channels. The Journal of General Physiology. 111: 313-42. PMID 9450946 DOI: 10.1085/Jgp.111.2.313 |
0.471 |
|
1998 |
Schoppa NE, Sigworth FJ. Activation of Shaker potassium channels. II. Kinetics of the V2 mutant channel. The Journal of General Physiology. 111: 295-311. PMID 9450945 DOI: 10.1085/Jgp.111.2.295 |
0.42 |
|
1998 |
Schoppa NE, Sigworth FJ. Activation of shaker potassium channels. I. Characterization of voltage-dependent transitions. The Journal of General Physiology. 111: 271-94. PMID 9450944 DOI: 10.1085/Jgp.111.2.271 |
0.407 |
|
1998 |
Venkataramanan L, Kuc R, Sigworth FJ. Identification of hidden markov models for ion channel currents-Part II: State-dependent excess noise Ieee Transactions On Signal Processing. 46: 1916-1929. DOI: 10.1109/78.700964 |
0.368 |
|
1998 |
Venkataramanan L, Walsh JL, Kuc R, Sigworth FJ. Identification of hidden markov models for ion channel currents-Part I: Colored background noise Ieee Transactions On Signal Processing. 46: 1901-1915. DOI: 10.1109/78.700963 |
0.413 |
|
1997 |
Zheng J, Sigworth FJ. Selectivity changes during activation of mutant Shaker potassium channels. The Journal of General Physiology. 110: 101-17. PMID 9236204 DOI: 10.1085/Jgp.110.2.101 |
0.459 |
|
1997 |
Yang Y, Yan Y, Sigworth FJ. How does the W434F mutation block current in Shaker potassium channels? The Journal of General Physiology. 109: 779-89. PMID 9222903 DOI: 10.1085/Jgp.109.6.779 |
0.47 |
|
1997 |
Ayer RK, Sigworth FJ. Enhanced closed-state inactivation in a mutant Shaker K+ channel. The Journal of Membrane Biology. 157: 215-30. PMID 9178609 DOI: 10.1007/S002329900230 |
0.476 |
|
1997 |
Mathur R, Zheng J, Yan Y, Sigworth FJ. Role of the S3-S4 linker in Shaker potassium channel activation. The Journal of General Physiology. 109: 191-9. PMID 9041448 DOI: 10.1085/Jgp.109.2.191 |
0.458 |
|
1996 |
Cummins TR, Sigworth FJ. Impaired slow inactivation in mutant sodium channels. Biophysical Journal. 71: 227-36. PMID 8804606 DOI: 10.1016/S0006-3495(96)79219-6 |
0.406 |
|
1996 |
Andreose JS, Fumagalli G, Sigworth FJ, Caplan MJ. Real-time detection of the surface delivery of newly synthesized membrane proteins. Proceedings of the National Academy of Sciences of the United States of America. 93: 7661-6. PMID 8755532 DOI: 10.1073/Pnas.93.15.7661 |
0.354 |
|
1995 |
Sigworth FJ. Charge movement in the sodium channel. The Journal of General Physiology. 106: 1047-51. PMID 8786349 DOI: 10.1085/Jgp.106.6.1047 |
0.387 |
|
1994 |
Jiang C, Sigworth FJ, Haddad GG. Oxygen deprivation activates an ATP-inhibitable K+ channel in substantia nigra neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 5590-602. PMID 8083755 DOI: 10.1523/Jneurosci.14-09-05590.1994 |
0.448 |
|
1994 |
Sigworth FJ. Voltage gating of ion channels. Quarterly Reviews of Biophysics. 27: 1-40. PMID 7520590 DOI: 10.1017/S0033583500002894 |
0.463 |
|
1993 |
Cummins TR, Zhou J, Sigworth FJ, Ukomadu C, Stephan M, Ptácek LJ, Agnew WS. Functional consequences of a Na+ channel mutation causing hyperkalemic periodic paralysis. Neuron. 10: 667-78. PMID 8386527 DOI: 10.1016/0896-6273(93)90168-Q |
0.405 |
|
1993 |
Crouzy SC, Sigworth FJ. Fluctuations in ion channel gating currents. Analysis of nonstationary shot noise. Biophysical Journal. 64: 68-76. PMID 8381683 DOI: 10.1016/S0006-3495(93)81341-9 |
0.445 |
|
1993 |
McCormack K, Lin L, Sigworth FJ. Substitution of a hydrophobic residue alters the conformational stability of Shaker K+ channels during gating and assembly. Biophysical Journal. 65: 1740-8. PMID 8274662 DOI: 10.1016/S0006-3495(93)81202-5 |
0.43 |
|
1992 |
Schoppa NE, McCormack K, Tanouye MA, Sigworth FJ. The size of gating charge in wild-type and mutant Shaker potassium channels. Science (New York, N.Y.). 255: 1712-5. PMID 1553560 DOI: 10.1126/Science.1553560 |
0.367 |
|
1992 |
McCormack K, Lin L, Iverson LE, Tanouye MA, Sigworth FJ. Tandem linkage of Shaker K+ channel subunits does not ensure the stoichiometry of expressed channels. Biophysical Journal. 63: 1406-11. PMID 1477286 DOI: 10.1016/S0006-3495(92)81703-4 |
0.453 |
|
1992 |
Sigworth FJ, Zhou J. Ion channels. Analysis of nonstationary single-channel currents. Methods in Enzymology. 207: 746-62. PMID 1382211 DOI: 10.1016/0076-6879(92)07054-R |
0.369 |
|
1992 |
Ukomadu C, Zhou J, Sigworth FJ, Agnew WS. muI Na+ channels expressed transiently in human embryonic kidney cells: biochemical and biophysical properties. Neuron. 8: 663-76. PMID 1314619 DOI: 10.1016/0896-6273(92)90088-U |
0.438 |
|
1991 |
Bouzat C, Barrantes FJ, Sigworth FJ. Changes in channel properties of acetylcholine receptors during the time course of thiol chemical modifications. Pflã¼Gers Archiv : European Journal of Physiology. 418: 51-61. PMID 2041725 DOI: 10.1007/Bf00370451 |
0.435 |
|
1991 |
Heinemann SH, Sigworth FJ. Open channel noise. VI. Analysis of amplitude histograms to determine rapid kinetic parameters. Biophysical Journal. 60: 577-87. PMID 1718467 DOI: 10.1016/S0006-3495(91)82087-2 |
0.411 |
|
1991 |
Zhou JY, Potts JF, Trimmer JS, Agnew WS, Sigworth FJ. Multiple gating modes and the effect of modulating factors on the microI sodium channel. Neuron. 7: 775-85. PMID 1660285 DOI: 10.1016/0896-6273(91)90280-D |
0.362 |
|
1991 |
Shenkel S, Sigworth FJ. Patch recordings from the electrocytes of Electrophorus electricus. Na currents and PNa/PK variability. The Journal of General Physiology. 97: 1013-41. PMID 1650809 DOI: 10.1085/Jgp.97.5.1013 |
0.406 |
|
1990 |
Sine SM, Claudio T, Sigworth FJ. Activation of Torpedo acetylcholine receptors expressed in mouse fibroblasts. Single channel current kinetics reveal distinct agonist binding affinities. The Journal of General Physiology. 96: 395-437. PMID 1698917 DOI: 10.1085/Jgp.96.2.395 |
0.357 |
|
1990 |
Crouzy SC, Sigworth FJ. Yet another approach to the dwell-time omission problem of single-channel analysis. Biophysical Journal. 58: 731-43. PMID 1698473 DOI: 10.1016/S0006-3495(90)82416-4 |
0.328 |
|
1990 |
Heinemann SH, Sigworth FJ. Open channel noise. V. Fluctuating barriers to ion entry in gramicidin A channels. Biophysical Journal. 57: 499-514. PMID 1689592 DOI: 10.1016/S0006-3495(90)82566-2 |
0.428 |
|
1989 |
Trimmer JS, Cooperman SS, Tomiko SA, Zhou JY, Crean SM, Boyle MB, Kallen RG, Sheng ZH, Barchi RL, Sigworth FJ. Primary structure and functional expression of a mammalian skeletal muscle sodium channel. Neuron. 3: 33-49. PMID 2559760 DOI: 10.1016/0896-6273(89)90113-X |
0.393 |
|
1989 |
Shenkel S, Cooper EC, James W, Agnew WS, Sigworth FJ. Purified, modified eel sodium channels are active in planar bilayers in the absence of activating neurotoxins. Proceedings of the National Academy of Sciences of the United States of America. 86: 9592-6. PMID 2556720 DOI: 10.1073/Pnas.86.23.9592 |
0.498 |
|
1989 |
Heinemann SH, Sigworth FJ. Estimation of Na+ dwell time in the gramicidin A channel. Na+ ions as blockers of H+ currents. Biochimica Et Biophysica Acta. 987: 8-14. PMID 2480817 DOI: 10.1016/0005-2736(89)90448-3 |
0.443 |
|
1989 |
Stankovic CJ, Heinemann SH, Delfino JM, Sigworth FJ, Schreiber SL. Transmembrane channels based on tartaric acid-gramicidin A hybrids. Science (New York, N.Y.). 244: 813-7. PMID 2471263 DOI: 10.1126/Science.2471263 |
0.463 |
|
1988 |
Heinemann SH, Sigworth FJ. Open channel noise. IV. Estimation of rapid kinetics of formamide block in gramicidin A channels. Biophysical Journal. 54: 757-64. PMID 2465033 DOI: 10.1016/S0006-3495(88)83013-3 |
0.486 |
|
1988 |
Sigworth FJ, Shenkel S. Chapter 6 Rapid Gating Events and Current Fluctuations in Gramicidin A Channel Current Topics in Membranes and Transport. 33: 113-130. DOI: 10.1016/S0070-2161(08)60896-5 |
0.39 |
|
1987 |
Claudio T, Green WN, Hartman DS, Hayden D, Paulson HL, Sigworth FJ, Sine SM, Swedlund A. Genetic reconstitution of functional acetylcholine receptor channels in mouse fibroblasts. Science (New York, N.Y.). 238: 1688-94. PMID 3686008 DOI: 10.1126/Science.3686008 |
0.318 |
|
1987 |
Sigworth FJ, Urry DW, Prasad KU. Open channel noise. III. High-resolution recordings show rapid current fluctuations in gramicidin A and four chemical analogues. Biophysical Journal. 52: 1055-64. PMID 2447969 DOI: 10.1016/S0006-3495(87)83299-X |
0.394 |
|
1987 |
Sigworth FJ, Sine SM. Data transformations for improved display and fitting of single-channel dwell time histograms. Biophysical Journal. 52: 1047-54. PMID 2447968 DOI: 10.1016/S0006-3495(87)83298-8 |
0.342 |
|
1986 |
Sigworth FJ. Open channel noise. II. A test for coupling between current fluctuations and conformational transitions in the acetylcholine receptor. Biophysical Journal. 49: 1041-6. PMID 2423148 DOI: 10.1016/S0006-3495(86)83732-8 |
0.323 |
|
1985 |
Sigworth FJ. Open channel noise. I. Noise in acetylcholine receptor currents suggests conformational fluctuations. Biophysical Journal. 47: 709-20. PMID 2410044 DOI: 10.1016/S0006-3495(85)83968-0 |
0.46 |
|
1981 |
Hamill OP, Marty A, Neher E, Sakmann B, Sigworth FJ. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflã¼Gers Archiv : European Journal of Physiology. 391: 85-100. PMID 6270629 DOI: 10.1007/Bf00656997 |
0.44 |
|
1981 |
Sigworth FJ. Interpreting power spectra from nonstationary membrane current fluctuations. Biophysical Journal. 35: 289-300. PMID 6268213 DOI: 10.1016/S0006-3495(81)84790-X |
0.427 |
|
1981 |
Sigworth FJ. Covariance of nonstationary sodium current fluctuations at the node of Ranvier. Biophysical Journal. 34: 111-33. PMID 6260261 DOI: 10.1016/S0006-3495(81)84840-0 |
0.358 |
|
1980 |
Sigworth FJ, Spalding BC. Chemical modification reduces the conductance of sodium channels in nerve. Nature. 283: 293-5. PMID 6965422 DOI: 10.1038/283293A0 |
0.49 |
|
1980 |
Sigworth FJ. The variance of sodium current fluctuations at the node of Ranvier. The Journal of Physiology. 307: 97-129. PMID 6259340 DOI: 10.1113/Jphysiol.1980.Sp013426 |
0.472 |
|
1980 |
Sigworth FJ. The conductance of sodium channels under conditions of reduced current at the node of Ranvier. The Journal of Physiology. 307: 131-42. PMID 6259331 DOI: 10.1113/Jphysiol.1980.Sp013427 |
0.425 |
|
1980 |
Sigworth FJ, Neher E. Single Na+ channel currents observed in cultured rat muscle cells. Nature. 287: 447-9. PMID 6253802 DOI: 10.1038/287447A0 |
0.489 |
|
1977 |
Sigworth FJ. Sodium channels in nerve apparently have two conductance states. Nature. 270: 265-7. PMID 593345 DOI: 10.1038/270265A0 |
0.456 |
|
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