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Thomas G. Graeber - Publications

Affiliations: 
University of California, Los Angeles, Los Angeles, CA 
Area:
Biomedical Engineering, Molecular Biology
Website:
https://www.pharmacology.ucla.edu/people/thomas-graeber-ph-d/
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47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Chen CC, Tran W, Song K, Sugimoto T, Obusan MB, Wang L, Sheu KM, Cheng D, Ta L, Varuzhanyan G, Huang A, Xu R, Zeng Y, Borujerdpur A, Bayley NA, ... ... Graeber TG, et al. Temporal evolution reveals bifurcated lineages in aggressive neuroendocrine small cell prostate cancer trans-differentiation. Cancer Cell. PMID 37995683 DOI: 10.1016/j.ccell.2023.10.009  0.308
2022 Shia DW, Choi W, Vijayaraj P, Vuong V, Sandlin JM, Lu MM, Aziz A, Marin C, Aros CJ, Sen C, Durra A, Lund AJ, Purkayastha A, Rickabaugh TM, Graeber TG, et al. Targeting PEA3 transcription factors to mitigate small cell lung cancer progression. Oncogene. PMID 36509998 DOI: 10.1038/s41388-022-02558-6  0.316
2020 Olcina MM, Kim RK, Balanis NG, Li CG, von Eyben R, Graeber TG, Ricklin D, Stucki M, Giaccia AJ. Intracellular C4BPA Levels Regulate NF-κB-Dependent Apoptosis. Iscience. 23: 101594. PMID 33205012 DOI: 10.1016/j.isci.2020.101594  0.515
2020 Court CM, Hou S, Liu L, Winograd P, DiPardo BJ, Liu SX, Chen PJ, Zhu Y, Smalley M, Zhang R, Sadeghi S, Finn RS, Kaldas FM, Busuttil RW, Zhou XJ, ... ... Graeber TG, et al. Somatic copy number profiling from hepatocellular carcinoma circulating tumor cells. Npj Precision Oncology. 4: 16. PMID 32637655 DOI: 10.1200/Jco.2018.36.4_Suppl.290  0.361
2020 Shia DW, Vuong V, Pecora E, Balanis N, Vijayaraj P, Sen C, Aros CJ, Rickabaugh T, Graeber T, Gomperts B. B06 Time-Resolved RNA-Seq Identifies Transient Gene Expression Changes Following Initial Chemotherapy Challenge in Small-Cell Lung Cancer Journal of Thoracic Oncology. 15. DOI: 10.1016/J.Jtho.2019.12.075  0.351
2019 Wang L, Smith BA, Balanis NG, Tsai BL, Nguyen K, Cheng MW, Obusan MB, Esedebe FN, Patel SJ, Zhang H, Clark PM, Sisk AE, Said JW, Huang J, Graeber TG, et al. A genetically defined disease model reveals that urothelial cells can initiate divergent bladder cancer phenotypes. Proceedings of the National Academy of Sciences of the United States of America. PMID 31871155 DOI: 10.1073/Pnas.1915770117  0.302
2019 Balanis NG, Sheu KM, Esedebe FN, Patel SJ, Smith BA, Park JW, Alhani S, Gomperts BN, Huang J, Witte ON, Graeber TG. Pan-cancer Convergence to a Small-Cell Neuroendocrine Phenotype that Shares Susceptibilities with Hematological Malignancies. Cancer Cell. 36: 17-34.e7. PMID 31287989 DOI: 10.1016/J.Ccell.2019.06.005  0.354
2019 Olcina MM, Balanis NG, Kim RK, Thompson MJ, Graeber TG, Giaccia AJ. Abstract A097: Complement system mutations in cancer: Uncovering new relationships between tumor hypoxia and complement Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-A097  0.527
2019 Graeber T. Abstract ES6-3: Systems approaches to attacking cancer vulnerabilities defined by metabolic, de-differentiation and genomic instability states Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-Es6-3  0.44
2019 Bayley N, Tse C, Baufeld L, Gosa L, Yan W, Zhu H, Balanis N, Cloughesy T, Liau L, Graeber T, Nathanson D. TMIC-26. PRECLINICAL MODEL SYSTEMS OF GLIOBLASTOMA REVEAL MICROENVIRONMENTAL PROGRAMS AND DEPENDENCIES IN PATIENT TUMORS Neuro-Oncology. 21: vi253-vi253. DOI: 10.1093/Neuonc/Noz175.1060  0.39
2018 Olcina MM, Balanis NG, Kim RK, Aksoy BA, Kodysh J, Thompson MJ, Hammerbacher J, Graeber TG, Giaccia AJ. Mutations in an Innate Immunity Pathway Are Associated with Poor Overall Survival Outcomes and Hypoxic Signaling in Cancer. Cell Reports. 25: 3721-3732.e6. PMID 30590044 DOI: 10.1016/J.Celrep.2018.11.093  0.541
2018 Park JW, Lee JK, Sheu KM, Wang L, Balanis NG, Nguyen K, Smith BA, Cheng C, Tsai BL, Cheng D, Huang J, Kurdistani SK, Graeber TG, Witte ON. Reprogramming normal human epithelial tissues to a common, lethal neuroendocrine cancer lineage. Science (New York, N.Y.). 362: 91-95. PMID 30287662 DOI: 10.1126/Science.Aat5749  0.325
2018 Xu S, Catapang A, Braas D, Stiles L, Doh HM, Lee JT, Graeber TG, Damoiseaux R, Shirihai O, Herschman HR. A precision therapeutic strategy for hexokinase 1-null, hexokinase 2-positive cancers. Cancer & Metabolism. 6: 7. PMID 29988332 DOI: 10.1186/S40170-018-0181-8  0.312
2018 Xu S, Catapang A, Doh HM, Bayley NA, Lee JT, Braas D, Graeber TG, Herschman HR. Hexokinase 2 is targetable for HK1 negative, HK2 positive tumors from a wide variety of tissues of origin. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 29880505 DOI: 10.2967/Jnumed.118.212365  0.326
2018 Lee JK, Bangayan NJ, Chai T, Smith BA, Pariva TE, Yun S, Vashisht A, Zhang Q, Park JW, Corey E, Huang J, Graeber TG, Wohlschlegel J, Witte ON. Systemic surfaceome profiling identifies target antigens for immune-based therapy in subtypes of advanced prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. PMID 29686080 DOI: 10.1073/Pnas.1802354115  0.312
2018 Hu-Lieskovan S, Torrejon DY, Zaretsky JM, Tsoi J, Cheung-Lau G, Vega-Crespo A, Meeth K, Prins RM, Graeber T, Besenberg M, Grasso C, Comin-Anduix B, Ribas A. Role of CD4 cells in the complete anti-tumor response to PD1 blockade in a syngeneic murine melanoma model with activated WNT signaling. Journal of Clinical Oncology. 36: 12013-12013. DOI: 10.1200/Jco.2018.36.15_Suppl.12013  0.34
2018 Momcilovic M, Bailey ST, Lee JT, Magyar C, Braas D, Graeber T, Parlati F, Demo S, Krysan K, Walser TC, Dubinett SM, Sadeghi S, Christofk HR, Shackelford DB. Abstract B28: Targeted inhibition of EGFR and glutaminase induces metabolic crisis in EGFR-mutant lung cancer Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Aacriaslc18-B28  0.426
2018 Olcina MM, Balanis NG, Kim RK, Thompson MJ, Graeber TG, Giaccia AJ. Abstract 4382: Complement system mutational landscape reveals C4BPA mutations enhance apoptosis in an immune-independent manner Cancer Research. 78: 4382-4382. DOI: 10.1158/1538-7445.Am2018-4382  0.499
2017 Flores A, Schell J, Krall AS, Jelinek D, Miranda M, Grigorian M, Braas D, White AC, Zhou JL, Graham NA, Graeber T, Seth P, Evseenko D, Coller HA, Rutter J, et al. Lactate dehydrogenase activity drives hair follicle stem cell activation. Nature Cell Biology. PMID 28812580 DOI: 10.1038/Ncb3575  0.322
2017 Graham NA, Minasyan A, Lomova A, Cass A, Balanis NG, Friedman M, Chan S, Zhao S, Delgado A, Go J, Beck L, Hurtz C, Ng C, Qiao R, Ten Hoeve J, ... ... Graeber TG, et al. Recurrent patterns of DNA copy number alterations in tumors reflect metabolic selection pressures. Molecular Systems Biology. 13: 914. PMID 28202506 DOI: 10.15252/Msb.20167159  0.32
2017 Momcilovic M, Bailey ST, Lee JT, Fishbein MC, Magyar C, Braas D, Graeber T, Jackson NJ, Czernin J, Emberley E, Gross M, Janes J, Mackinnon A, Pan A, Rodriguez M, et al. Targeted Inhibition of EGFR and Glutaminase Induces Metabolic Crisis in EGFR Mutant Lung Cancer. Cell Reports. 18: 601-610. PMID 28099841 DOI: 10.1016/J.Celrep.2016.12.061  0.424
2017 Momcilovic M, Bailey ST, Lee JT, Braas D, Graeber TG, Works M, Parlati F, Demo S, Walser TC, Dubinett SM, Sadeghi S, Christofk H, Shackelford DB. Abstract 1830: Targeted inhibition of EGFR and glutaminase induces metabolic crisis in EGFR mutant lung cancer Cancer Research. 77: 1830-1830. DOI: 10.1158/1538-7445.Am2017-1830  0.323
2016 Drake JM, Paull EO, Graham NA, Lee JK, Smith BA, Titz B, Stoyanova T, Faltermeier CM, Uzunangelov V, Carlin DE, Fleming DT, Wong CK, Newton Y, Sudha S, Vashisht AA, ... ... Graeber TG, et al. Phosphoproteome Integration Reveals Patient-Specific Networks in Prostate Cancer. Cell. PMID 27499020 DOI: 10.1016/J.Cell.2016.07.007  0.37
2016 Sood A, Miller AM, Brogi E, Sui Y, Armenia J, McDonough E, Santamaria-Pang A, Carlin S, Stamper A, Campos C, Pang Z, Li Q, Port E, Graeber TG, Schultz N, et al. Multiplexed immunofluorescence delineates proteomic cancer cell states associated with metabolism. Jci Insight. 1. PMID 27182557 DOI: 10.1172/jci.insight.87030  0.317
2016 Hong CS, Graham NA, Gu W, Espindola Camacho C, Mah V, Maresh EL, Alavi M, Bagryanova L, Krotee PA, Gardner BK, Behbahan IS, Horvath S, Chia D, Mellinghoff IK, Hurvitz SA, ... ... Graeber TG, et al. MCT1 Modulates Cancer Cell Pyruvate Export and Growth of Tumors that Co-express MCT1 and MCT4. Cell Reports. PMID 26876179 DOI: 10.1016/J.Celrep.2016.01.057  0.336
2016 Su Y, Wei W, Xue M, Robert L, Tsoi J, Graeber T, Ribas A, Heath J. Abstract 879: Single cell analysis resolves combinatory targeted therapy for arresting the BRAFi-induced cellular dedifferentiation of metastatic melanomas Cancer Research. 76: 879-879. DOI: 10.1158/1538-7445.Am2016-879  0.394
2016 Drake JM, Paull EO, Graham NA, Lee JK, Smith BA, Stoyanova T, Faltermeier CM, Carlin DE, Vashisht A, Huang J, Wohlschlegel JA, Graeber TG, Witte ON, Stuart JM. Abstract 3882: Patient-specific druggable networks in lethal prostate cancer through proteome-guided multi-omic integration Cancer Research. 76: 3882-3882. DOI: 10.1158/1538-7445.Am2016-3882  0.353
2015 Ting PY, Johnson CW, Fang C, Cao X, Graeber TG, Mattos C, Colicelli J. Tyrosine phosphorylation of RAS by ABL allosterically enhances effector binding. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 25999467 DOI: 10.1096/Fj.15-271510  0.539
2015 Chan LN, Braas D, Hurtz C, Shojaee S, Geng H, Cazzaniga V, Ng C, Masouleh BK, Qiu YH, Zhang N, Coombes KR, Ernst T, Cazzaniga G, Hochhaus A, Kornblau S, ... Graeber T, et al. Abstract 1124: Transcriptional control of B cell identity restricts metabolic fitness in human leukemia Cancer Research. 75: 1124-1124. DOI: 10.1158/1538-7445.Am2015-1124  0.338
2014 Atefi M, Avramis E, Lassen A, Wong DJ, Robert L, Foulad D, Cerniglia M, Titz B, Chodon T, Graeber TG, Comin-Anduix B, Ribas A. Effects of MAPK and PI3K pathways on PD-L1 expression in melanoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 3446-57. PMID 24812408 DOI: 10.1158/1078-0432.Ccr-13-2797  0.305
2014 Chan LN, Braas D, Hurtz C, Shojaee S, Kharabi Masouleh B, Geng H, Ernst T, Hochhaus A, Graeber T, Muschen M. Lineage-Specific Metabolic Reprogramming Reveals LKB1 as Therapeutic Target in Acute Lymphoblastic Leukemia Blood. 124: 783-783. DOI: 10.1182/Blood.V124.21.783.783  0.367
2014 Mok S, Koya R, Tsoi J, Robert L, Zaretsky J, Tsui C, Graeber T, Ribas A. Abstract 147: Improving antitumor effects of a BRAF inhibitor with a colony stimulating factor 1 receptor (CSF-1R) inhibitor, PLX3397 Cancer Research. 74: 147-147. DOI: 10.1158/1538-7445.Am2014-147  0.336
2013 Drake JM, Graham NA, Lee JK, Stoyanova T, Faltermeier CM, Sud S, Titz B, Huang J, Pienta KJ, Graeber TG, Witte ON. Metastatic castration-resistant prostate cancer reveals intrapatient similarity and interpatient heterogeneity of therapeutic kinase targets. Proceedings of the National Academy of Sciences of the United States of America. 110: E4762-9. PMID 24248375 DOI: 10.1073/Pnas.1319948110  0.302
2012 Tran LM, Chang CJ, Plaisier S, Wu S, Dang J, Mischel PS, Liao JC, Graeber TG, Wu H. Determining PTEN functional status by network component deduced transcription factor activities. Plos One. 7: e31053. PMID 22347425 DOI: 10.1371/Journal.Pone.0031053  0.746
2012 Geng H, Nahar R, Ramezani-Rad P, Chen Z, Tyner JW, Chang BH, Titz B, Buchner M, Hurtz C, Graeber TG, Druker BJ, Paietta E, Melnick A, Willman CL, Carroll WL, et al. Integrative Analysis of Ikaros-Dependent Changes of Transcriptional Regulation and Tyrosine Phosphorylation Events in Ph+ ALL Blood. 120: 528-528. DOI: 10.1182/Blood.V120.21.528.528  0.311
2011 Palaskas N, Larson SM, Schultz N, Komisopoulou E, Wong J, Rohle D, Campos C, Yannuzzi N, Osborne JR, Linkov I, Kastenhuber ER, Taschereau R, Plaisier SB, Tran C, Heguy A, ... ... Graeber TG, et al. 18F-fluorodeoxy-glucose positron emission tomography marks MYC-overexpressing human basal-like breast cancers. Cancer Research. 71: 5164-74. PMID 21646475 DOI: 10.1158/0008-5472.Can-10-4633  0.719
2011 Mulholland DJ, Tran LM, Li Y, Cai H, Morim A, Wang S, Plaisier S, Garraway IP, Huang J, Graeber TG, Wu H. Cell autonomous role of PTEN in regulating castration-resistant prostate cancer growth. Cancer Cell. 19: 792-804. PMID 21620777 DOI: 10.1016/J.Ccr.2011.05.006  0.729
2010 Fang C, Wang Y, Vu NT, Lin WY, Hsieh YT, Rubbi L, Phelps ME, Müschen M, Kim YM, Chatziioannou AF, Tseng HR, Graeber TG. Integrated microfluidic and imaging platform for a kinase activity radioassay to analyze minute patient cancer samples. Cancer Research. 70: 8299-308. PMID 20837665 DOI: 10.1158/0008-5472.Can-10-0851  0.56
2010 Plaisier SB, Taschereau R, Wong JA, Graeber TG. Rank-rank hypergeometric overlap: identification of statistically significant overlap between gene-expression signatures. Nucleic Acids Research. 38: e169. PMID 20660011 DOI: 10.1093/Nar/Gkq636  0.716
2009 Lu KV, Zhu S, Cvrljevic A, Huang TT, Sarkaria S, Ahkavan D, Dang J, Dinca EB, Plaisier SB, Oderberg I, Lee Y, Chen Z, Caldwell JS, Xie Y, Loo JA, ... ... Graeber T, et al. Fyn and SRC are effectors of oncogenic epidermal growth factor receptor signaling in glioblastoma patients. Cancer Research. 69: 6889-98. PMID 19690143 DOI: 10.1158/0008-5472.Can-09-0347  0.716
2003 Ellwood-Yen K, Graeber TG, Wongvipat J, Iruela-Arispe ML, Zhang J, Matusik R, Thomas GV, Sawyers CL. Myc-driven murine prostate cancer shares molecular features with human prostate tumors. Cancer Cell. 4: 223-38. PMID 14522256 DOI: 10.1016/S1535-6108(03)00197-1  0.305
2003 Freedland SJ, Pantuck AJ, Paik SH, Zisman A, Graeber TG, Eisenberg D, McBride WH, Nguyen D, Tso CL, Belldegrun AS. Heterogeneity of molecular targets on clonal cancer lines derived from a novel hormone-refractory prostate cancer tumor system. The Prostate. 55: 299-307. PMID 12712409 DOI: 10.1002/Pros.10226  0.309
1997 Kim CY, Tsai MH, Osmanian C, Calkins DP, Graeber TG, Greenspan DL, Kennedy AS, Rinker LH, Varia MA, DiPaolo JA, Peehl DM, Raleigh JA, Giaccia AJ. 142 The role of hypoxia, p53, and apoptosis in human cervical carcinoma pathogenesis International Journal of Radiation Oncology*Biology*Physics. 39: 206. DOI: 10.1016/S0360-3016(97)80701-8  0.376
1996 Graeber TG, Osmanian C, Jacks T, Housman DE, Koch CJ, Lowe SW, Giaccia AJ. Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours. Nature. 379: 88-91. PMID 8538748 DOI: 10.1038/379088A0  0.447
1996 Kim CY, Tsai M, Graeber TG, Peehl DM, Giaccia AJ. 2210 HPV E6 and E7 in hypoxia mediated tumorigenesis in cervical epithelial cells International Journal of Radiation Oncology*Biology*Physics. 36: 379. DOI: 10.1016/S0360-3016(97)85781-1  0.355
1994 Graeber TG, Peterson JF, Tsai M, Monica K, Fornace AJ, Giaccia AJ. Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low-oxygen conditions is independent of p53 status. Molecular and Cellular Biology. 14: 6264-77. PMID 8065358 DOI: 10.1128/mcb.14.9.6264-6277.1994  0.428
1994 Graeber TG, Monica KA, Fornace AJ, Giaccia AJ. Low oxygen conditions activate a G1/S-phase checkpoint independent of p53 status International Journal of Radiation Oncology*Biology*Physics. 30: 196. DOI: 10.1016/0360-3016(94)90701-3  0.37
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