Wolfram Goessling - Publications

Affiliations: 
Biology: Medical Sciences, Division of Harvard University, Cambridge, MA, United States 
Area:
Genetics, Human Development

90 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Tzouanas CN, Sherman MS, Shay JES, Rubin AJ, Mead BE, Dao TT, Butzlaff T, Mana MD, Kolb KE, Walesky C, Pepe-Mooney BJ, Smith CJ, Prakadan SM, Ramseier ML, Tong EY, ... ... Goessling W, et al. Chronic metabolic stress drives developmental programs and loss of tissue functions in non-transformed liver that mirror tumor states and stratify survival. Biorxiv : the Preprint Server For Biology. PMID 38077056 DOI: 10.1101/2023.11.30.569407  0.744
2020 Frame JM, Kubaczka C, Long TL, Esain V, Soto RA, Hachimi M, Jing R, Shwartz A, Goessling W, Daley GQ, North TE. Metabolic Regulation of Inflammasome Activity Controls Embryonic Hematopoietic Stem and Progenitor Cell Production. Developmental Cell. PMID 32810442 DOI: 10.1016/J.Devcel.2020.07.015  0.368
2020 Freeburg SH, Goessling W. Hepatobiliary Differentiation: Principles from Embryonic Liver Development. Seminars in Liver Disease. PMID 32526786 DOI: 10.1055/S-0040-1709679  0.38
2020 Chaturantabut S, Shwartz A, Garnaas MK, LaBella K, Li CC, Carroll KJ, Cutting CC, Budrow N, Palaria A, Gorelick DA, Tremblay KD, North TE, Goessling W. Estrogen acts via estrogen receptor 2b to regulate hepatobiliary fate during vertebrate development. Hepatology (Baltimore, Md.). PMID 32060934 DOI: 10.1002/Hep.31184  0.762
2020 Lundin V, Sugden WW, Theodore LN, Sousa PM, Han A, Chou S, Wrighton PJ, Cox AG, Ingber DE, Goessling W, Daley GQ, North TE. YAP Regulates Hematopoietic Stem Cell Formation in Response to the Biomechanical Forces of Blood Flow. Developmental Cell. PMID 32032546 DOI: 10.1016/J.Devcel.2020.01.006  0.362
2019 Shwartz A, Goessling W, Yin C. Macrophages in Zebrafish Models of Liver Diseases. Frontiers in Immunology. 10: 2840. PMID 31867007 DOI: 10.3389/Fimmu.2019.02840  0.307
2019 Nissim S, Leshchiner I, Mancias JD, Greenblatt MB, Maertens O, Cassa CA, Rosenfeld JA, Cox AG, Hedgepeth J, Wucherpfennig JI, Kim AJ, Henderson JE, Gonyo P, Brandt A, Lorimer E, ... ... Goessling W, et al. Mutations in RABL3 alter KRAS prenylation and are associated with hereditary pancreatic cancer. Nature Genetics. PMID 31406347 DOI: 10.1038/S41588-019-0475-Y  0.67
2019 Chambers BE, Gerlach GF, Clark EG, Chen KH, Levesque AE, Leshchiner I, Goessling W, Wingert RA. Tfap2a is a novel gatekeeper of nephron differentiation during kidney development. Development (Cambridge, England). PMID 31160420 DOI: 10.1242/Dev.172387  0.338
2019 Goessling W. Position Is Destiny: Metabolism and Cell Identity. Cell Metabolism. 29: 1017-1019. PMID 31067445 DOI: 10.1016/J.Cmet.2019.04.008  0.315
2019 Chaturantabut S, Shwartz A, Evason KJ, Cox AG, Labella K, Schepers AG, Yang S, Aravena M, Houvras Y, Mancio-Silva L, Romano S, Gorelick DA, Cohen DE, Zon LI, Bhatia SN, ... ... Goessling W, et al. Estrogen Activation of G protein-coupled Estrogen Receptor 1 Regulates Phosphoinositide 3-kinase and mTOR Signaling to Promote Liver Growth in Zebrafish and Proliferation of Human Hepatocytes. Gastroenterology. PMID 30641053 DOI: 10.1053/J.Gastro.2019.01.010  0.335
2019 Soto R, rocha ELd, Wrighton P, Daley G, Goessling W, North T. Investigating The Role Of Ezh1 In Developmental Hematopoiesis Experimental Hematology. 76. DOI: 10.1016/J.Exphem.2019.06.437  0.403
2018 Cox AG, Tsomides A, Yimlamai D, Hwang KL, Miesfeld J, Galli GG, Fowl BH, Fort M, Ma KY, Sullivan MR, Hosios AM, Snay E, Yuan M, Brown KK, Lien EC, ... ... Goessling W, et al. Yap regulates glucose utilization and sustains nucleotide synthesis to enable organ growth. The Embo Journal. PMID 30348863 DOI: 10.15252/Embj.2018100294  0.327
2017 Kroeger PT, Drummond BE, Miceli R, McKernan M, Gerlach GF, Marra AN, Fox A, McCampbell KK, Leshchiner I, Rodriguez-Mari A, BreMiller R, Thummel R, Davidson AJ, Postlethwait J, Goessling W, et al. The zebrafish kidney mutant zeppelin reveals that brca2/fancd1 is essential for pronephros development. Developmental Biology. PMID 28579318 DOI: 10.1016/J.Ydbio.2017.05.025  0.367
2017 Nissim S, Leshchiner I, Mancias JD, Greenblatt MB, Maertens O, Cassa CA, Rosenfeld JA, Cox AG, Hedgepeth J, Wücherpfennig J, Kim AJ, Henderson JE, Gonyo P, Brandt A, Lorimer E, ... ... Goessling W, et al. Abstract 4272: Mutations inRABL3alter RAS prenylation and are associated with hereditary pancreatic cancer Epidemiology. 77: 4272-4272. DOI: 10.1158/1538-7445.Am2017-4272  0.647
2016 North TE, Goessling W. Haematopoietic stem cells show their true colours. Nature Cell Biology. 19: 10-12. PMID 28008181 DOI: 10.1038/Ncb3459  0.353
2016 Li M, Li Y, Weeks O, Mijatovic V, Teumer A, Huffman JE, Tromp G, Fuchsberger C, Gorski M, Lyytikäinen LP, Nutile T, Sedaghat S, Sorice R, Tin A, Yang Q, ... ... Goessling W, et al. SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function. Journal of the American Society of Nephrology : Jasn. PMID 27920155 DOI: 10.1681/Asn.2016020131  0.345
2016 Chu AY, Deng X, Fisher VA, Drong A, Zhang Y, Feitosa MF, Liu CT, Weeks O, Choh AC, Duan Q, Dyer TD, Eicher JD, Guo X, Heard-Costa NL, Kacprowski T, ... ... Goessling W, et al. Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation. Nature Genetics. PMID 27918534 DOI: 10.1038/Ng.3738  0.31
2016 Cox AG, Tsomides A, Kim AJ, Saunders D, Hwang KL, Evason KJ, Heidel J, Brown KK, Yuan M, Lien EC, Lee BC, Nissim S, Dickinson B, Chhangawala S, Chang CJ, ... ... Goessling W, et al. Selenoprotein H is an essential regulator of redox homeostasis that cooperates with p53 in development and tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 27588899 DOI: 10.1073/Pnas.1600204113  0.685
2016 Nissim S, Weeksb O, Talbot JC, Hedgepeth JW, Wucherpfennig J, Schatzman-Bone S, Swinburne I, Cortes M, Alexa K, Megason S, North TE, Amacher SL, Goessling W. Iterative use of nuclear receptor Nr5a2 regulates multiple stages of liver and pancreas development. Developmental Biology. PMID 27474396 DOI: 10.1016/J.Ydbio.2016.07.019  0.712
2016 Cox AG, Hwang KL, Brown KK, Evason KJ, Beltz S, Tsomides A, O'Connor K, Galli GG, Yimlamai D, Chhangawala S, Yuan M, Lien EC, Wucherpfennig J, Nissim S, Minami A, ... ... Goessling W, et al. Yap reprograms glutamine metabolism to increase nucleotide biosynthesis and enable liver growth. Nature Cell Biology. PMID 27428308 DOI: 10.1038/Ncb3389  0.705
2016 Kwan W, Cortes M, Frost I, Esain V, Theodore LN, Liu SY, Budrow N, Goessling W, North TE. The Central Nervous System Regulates Embryonic HSPC Production via Stress-Responsive Glucocorticoid Receptor Signaling. Cell Stem Cell. PMID 27424782 DOI: 10.1016/J.Stem.2016.06.004  0.334
2016 Goessling W, Stainier DY. Endoderm specification and liver development. Methods in Cell Biology. 134: 463-83. PMID 27312502 DOI: 10.1016/Bs.Mcb.2016.03.042  0.329
2016 Goessling W, North TE. EnaBILEing Growth in the Fetal Liver. Cell Stem Cell. 18: 427-8. PMID 27058931 DOI: 10.1016/J.Stem.2016.03.019  0.338
2016 Raman M, Sergeev M, Garnaas M, Lydeard JR, Huttlin EL, Goessling W, Shah JV, Harper JW. Corrigendum: Systematic proteomics of the VCP-UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis. Nature Cell Biology. 18: 347. PMID 26911913 DOI: 10.1038/Ncb3318  0.709
2016 Liu LY, Alexa K, Cortes M, Schatzman-Bone S, Kim AJ, Mukhopadhyay B, Cinar R, Kunos G, North TE, Goessling W. Cannabinoid receptor signaling regulates liver development and metabolism. Development (Cambridge, England). 143: 609-22. PMID 26884397 DOI: 10.1242/Dev.121731  0.401
2016 Pattaro C, Teumer A, Gorski M, Chu AY, Li M, Mijatovic V, Garnaas M, Tin A, Sorice R, Li Y, Taliun D, Olden M, Foster M, Yang Q, Chen MH, ... ... Goessling W, et al. Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function. Nature Communications. 7: 10023. PMID 26831199 DOI: 10.1038/Ncomms10023  0.745
2015 Mancias JD, Pontano Vaites L, Nissim S, Biancur DE, Kim AJ, Wang X, Liu Y, Goessling W, Kimmelman AC, Harper JW. Ferritinophagy via NCOA4 is required for erythropoiesis and is regulated by iron dependent HERC2-mediated proteolysis. Elife. 4. PMID 26436293 DOI: 10.7554/Elife.10308  0.646
2015 Raman M, Sergeev M, Garnaas M, Lydeard JR, Huttlin EL, Goessling W, Shah JV, Harper JW. Systematic proteomics of the VCP-UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis. Nature Cell Biology. PMID 26389662 DOI: 10.1038/Ncb3238  0.726
2015 Cortes M, Liu SY, Kwan W, Alexa K, Goessling W, North TE. Accumulation of the Vitamin D Precursor Cholecalciferol Antagonizes Hedgehog Signaling to Impair Hemogenic Endothelium Formation. Stem Cell Reports. 5: 471-9. PMID 26365513 DOI: 10.1016/J.Stemcr.2015.08.010  0.302
2015 Goessling W, Sadler KC. Zebrafish: An Important Tool for Liver Disease Research. Gastroenterology. 149: 1361-77. PMID 26319012 DOI: 10.1053/J.Gastro.2015.08.034  0.351
2015 Esain V, Kwan W, Carroll KJ, Cortes M, Liu SY, Frechette GM, Sheward LM, Nissim S, Goessling W, North TE. Cannabinoid Receptor-2 Regulates Embryonic Hematopoietic Stem Cell Development via Prostaglandin E2 and P-Selectin Activity. Stem Cells (Dayton, Ohio). PMID 25931248 DOI: 10.1002/Stem.2044  0.715
2015 Cox AG, Goessling W. The lure of zebrafish in liver research: regulation of hepatic growth in development and regeneration. Current Opinion in Genetics & Development. 32: 153-61. PMID 25863341 DOI: 10.1016/J.Gde.2015.03.002  0.352
2015 Czarnecki PG, Gabriel GC, Manning DK, Sergeev M, Lemke K, Klena NT, Liu X, Chen Y, Li Y, San Agustin JT, Garnaas MK, Francis RJ, Tobita K, Goessling W, Pazour GJ, et al. ANKS6 is the critical activator of NEK8 kinase in embryonic situs determination and organ patterning. Nature Communications. 6: 6023. PMID 25599650 DOI: 10.1038/Ncomms7023  0.722
2015 Gorski M, Tin A, Garnaas M, McMahon GM, Chu AY, Tayo BO, Pattaro C, Teumer A, Chasman DI, Chalmers J, Hamet P, Tremblay J, Woodward M, Aspelund T, Eiriksdottir G, ... ... Goessling W, et al. Genome-wide association study of kidney function decline in individuals of European descent. Kidney International. 87: 1017-29. PMID 25493955 DOI: 10.1038/Ki.2014.361  0.729
2015 Mancias JD, Vaites LP, Nissim S, Biancur DE, Kim AJ, Wang X, Liu Y, Goessling W, Kimmelman AC, Harper JW. Author response: Ferritinophagy via NCOA4 is required for erythropoiesis and is regulated by iron dependent HERC2-mediated proteolysis Elife. DOI: 10.7554/Elife.10308.014  0.644
2015 Kwan W, Cortes M, Liu S, Frost I, Goessling W, North T. Hypoxic Stress-Induced Serotonergic Stimulation Controls Hematopoietic Stem Cell Production Via the Hypothalamic-Pituitary-Interrenal Axis and Glucocorticoid Signaling Blood. 126: 895-895. DOI: 10.1182/Blood.V126.23.895.895  0.3
2015 Cox AG, Hwang KL, Evason K, Brown KK, Beltz S, O'Connor K, Galli GG, Yimlamai D, Chhangawala S, Lien E, Camargo FD, Asara J, Houvras Y, Stainier DY, Goessling W. Abstract 5151: Yap reprograms glutamine metabolism and supports growth during liver development and tumorigenesis Cancer Research. 75: 5151-5151. DOI: 10.1158/1538-7445.Am2015-5151  0.393
2015 Nissim S, Weeks O, Hedgepeth J, Wucherpfennig J, Wang X, Kimmelman A, Goessling W. Abstract 5148: NR5A2 is essential for pancreas development and affects pancreas carcinogenesis Cancer Research. 75: 5148-5148. DOI: 10.1158/1538-7445.Am2015-5148  0.664
2014 McMahon GM, Olden M, Garnaas M, Yang Q, Liu X, Hwang SJ, Larson MG, Goessling W, Fox CS. Sequencing of LRP2 reveals multiple rare variants associated with urinary trefoil factor-3. Journal of the American Society of Nephrology : Jasn. 25: 2896-905. PMID 24876117 DOI: 10.1681/Asn.2013111240  0.725
2014 Carroll KJ, Esain V, Garnaas MK, Cortes M, Dovey MC, Nissim S, Frechette GM, Liu SY, Kwan W, Cutting CC, Harris JM, Gorelick DA, Halpern ME, Lawson ND, Goessling W, et al. Estrogen defines the dorsal-ventral limit of VEGF regulation to specify the location of the hemogenic endothelial niche. Developmental Cell. 29: 437-53. PMID 24871948 DOI: 10.1016/J.Devcel.2014.04.012  0.764
2014 Cox AG, Goessling W. Regenerative biology: Take the brakes off for liver repair. Nature. 506: 299-300. PMID 24553235 DOI: 10.1038/506299A  0.347
2014 Nissim S, Sherwood RI, Wucherpfennig J, Saunders D, Harris JM, Esain V, Carroll KJ, Frechette GM, Kim AJ, Hwang KL, Cutting CC, Elledge S, North TE, Goessling W. Prostaglandin E2 regulates liver versus pancreas cell-fate decisions and endodermal outgrowth. Developmental Cell. 28: 423-37. PMID 24530296 DOI: 10.1016/J.Devcel.2014.01.006  0.715
2014 Cox AG, Saunders DC, Kelsey PB, Conway AA, Tesmenitsky Y, Marchini JF, Brown KK, Stamler JS, Colagiovanni DB, Rosenthal GJ, Croce KJ, North TE, Goessling W. S-nitrosothiol signaling regulates liver development and improves outcome following toxic liver injury Cell Reports. 6: 56-69. PMID 24388745 DOI: 10.1016/J.Celrep.2013.12.007  0.331
2014 Nissim S, Wucherpfennig J, Wang X, Kimmelman A, Goessling W. Abstract 1953: The role of NR5a2 in pancreas development and carcinogenesis Cancer Research. 74: 1953-1953. DOI: 10.1158/1538-7445.Am2014-1953  0.712
2014 Schwartz RE, Shan J, Duncan SA, Goessling W, Bhatia S. 762 Control of Microenvironmental Cues Enables the Differentiation of Pluripotent Stem Cell Derived Hepatocyte-Like Cells to an Adult Phenotype Gastroenterology. 146: S-926. DOI: 10.1016/S0016-5085(14)63363-1  0.394
2014 Kwan W, Cortes M, Goessling W, North T. Serotonergic regulation of hematopoietic stem cell production in the AGM Experimental Hematology. 42. DOI: 10.1016/J.Exphem.2014.07.161  0.32
2014 Cortes M, Chen M, Liu S, Stachura D, Schlaeger T, Traver D, Daley G, Goessling W, North T. Vitamin D regulates hematopoietic stem cell maintenance by two distinct mechanisms Experimental Hematology. 42: S13. DOI: 10.1016/J.Exphem.2014.07.044  0.301
2013 Cutler C, Multani P, Robbins D, Kim HT, Le T, Hoggatt J, Pelus LM, Desponts C, Chen YB, Rezner B, Armand P, Koreth J, Glotzbecker B, Ho VT, Alyea E, ... ... Goessling W, et al. Prostaglandin-modulated umbilical cord blood hematopoietic stem cell transplantation. Blood. 122: 3074-81. PMID 23996087 DOI: 10.1182/Blood-2013-05-503177  0.312
2013 Liu LY, Fox CS, North TE, Goessling W. Functional validation of GWAS gene candidates for abnormal liver function during zebrafish liver development. Disease Models & Mechanisms. 6: 1271-8. PMID 23813869 DOI: 10.1242/Dmm.011726  0.355
2013 Shan J, Schwartz RE, Ross NT, Logan DJ, Thomas D, Duncan SA, North TE, Goessling W, Carpenter AE, Bhatia SN. Identification of small molecules for human hepatocyte expansion and iPS differentiation. Nature Chemical Biology. 9: 514-20. PMID 23728495 DOI: 10.1038/Nchembio.1270  0.348
2013 Harris JM, Esain V, Frechette GM, Harris LJ, Cox AG, Cortes M, Garnaas MK, Carroll KJ, Cutting CC, Khan T, Elks PM, Renshaw SA, Dickinson BC, Chang CJ, Murphy MP, ... ... Goessling W, et al. Glucose metabolism impacts the spatiotemporal onset and magnitude of HSC induction in vivo. Blood. 121: 2483-93. PMID 23341543 DOI: 10.1182/Blood-2012-12-471201  0.743
2013 Carroll KJ, Dovey MC, Garnaas MK, Cutting CC, Frechette GM, Esain V, Nissim S, Kwan W, Harris JM, Gorelick D, Halpern M, Goessling W, North TE. Estrogens Act As a Dorsal-Ventral Limiting Factor To Pattern The Hematopoietic Stem Cell Niche Blood. 122: 465-465. DOI: 10.1182/Blood.V122.21.465.465  0.777
2013 Nissim S, Wucherpfennig J, Wang X, Kimmelman A, Goessling W. Abstract 2657: The role of NR5A2 in pancreas development and oncogenesis. Cancer Research. 73: 2657-2657. DOI: 10.1158/1538-7445.Am2013-2657  0.708
2013 Cox AG, Beltz S, Evason K, Stainier DY, North TE, Goessling W. Abstract 1574: The Hippo pathway regulates liver development and tumorigenesis in zebrafish. Cancer Research. 73: 1574-1574. DOI: 10.1158/1538-7445.Am2013-1574  0.39
2013 Carroll K, Dovey M, Cutting C, Garnaas M, Esain V, Frechette G, Nissim S, Kwan W, Harris J, Gorelick D, Halpern M, Goessling W, North T. 17beta-estradiol has a biphasic effect on the formation of hematopoietic stem cells Experimental Hematology. 41: S12. DOI: 10.1016/J.Exphem.2013.05.046  0.747
2012 Rosenbluh J, Nijhawan D, Cox AG, Li X, Neal JT, Schafer EJ, Zack TI, Wang X, Tsherniak A, Schinzel AC, Shao DD, Schumacher SE, Weir BA, Vazquez F, Cowley GS, ... ... Goessling W, et al. β-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis. Cell. 151: 1457-73. PMID 23245941 DOI: 10.1016/J.Cell.2012.11.026  0.331
2012 Garnaas MK, Cutting CC, Meyers A, Kelsey PB, Harris JM, North TE, Goessling W. Rargb regulates organ laterality in a zebrafish model of right atrial isomerism. Developmental Biology. 372: 178-89. PMID 22982668 DOI: 10.1016/J.Ydbio.2012.09.001  0.747
2012 Shaik S, Nucera C, Inuzuka H, Gao D, Garnaas M, Frechette G, Harris L, Wan L, Fukushima H, Husain A, Nose V, Fadda G, Sadow PM, Goessling W, North T, et al. SCF(β-TRCP) suppresses angiogenesis and thyroid cancer cell migration by promoting ubiquitination and destruction of VEGF receptor 2. The Journal of Experimental Medicine. 209: 1289-307. PMID 22711876 DOI: 10.1084/Jem.20112446  0.738
2012 Leshchiner I, Alexa K, Kelsey P, Adzhubei I, Austin-Tse CA, Cooney JD, Anderson H, King MJ, Stottmann RW, Garnaas MK, Ha S, Drummond IA, Paw BH, North TE, Beier DR, ... Goessling W, et al. Mutation mapping and identification by whole-genome sequencing. Genome Research. 22: 1541-8. PMID 22555591 DOI: 10.1101/Gr.135541.111  0.717
2012 Pattaro C, Köttgen A, Teumer A, Garnaas M, Böger CA, Fuchsberger C, Olden M, Chen MH, Tin A, Taliun D, Li M, Gao X, Gorski M, Yang Q, Hundertmark C, ... ... Goessling W, et al. Genome-wide association and functional follow-up reveals new loci for kidney function. Plos Genetics. 8: e1002584. PMID 22479191 DOI: 10.1371/Journal.Pgen.1002584  0.731
2011 Chambers JC, Zhang W, Sehmi J, Li X, Wass MN, Van der Harst P, Holm H, Sanna S, Kavousi M, Baumeister SE, Coin LJ, Deng G, Gieger C, Heard-Costa NL, Hottenga JJ, ... ... Goessling W, et al. Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. Nature Genetics. 43: 1131-8. PMID 22001757 DOI: 10.1038/Ng.970  0.352
2011 Goessling W, North TE. Hematopoietic stem cell development: using the zebrafish to identify the signaling networks and physical forces regulating hematopoiesis. Methods in Cell Biology. 105: 117-36. PMID 21951528 DOI: 10.1016/B978-0-12-381320-6.00005-9  0.35
2011 Liu CT, Garnaas MK, Tin A, Kottgen A, Franceschini N, Peralta CA, de Boer IH, Lu X, Atkinson E, Ding J, Nalls M, Shriner D, Coresh J, Kutlar A, Bibbins-Domingo K, ... ... Goessling W, et al. Genetic association for renal traits among participants of African ancestry reveals new loci for renal function. Plos Genetics. 7: e1002264. PMID 21931561 DOI: 10.1371/Journal.Pgen.1002264  0.727
2011 Saadi I, Alkuraya FS, Gisselbrecht SS, Goessling W, Cavallesco R, Turbe-Doan A, Petrin AL, Harris J, Siddiqui U, Grix AW, Hove HD, Leboulch P, Glover TW, Morton CC, Richieri-Costa A, et al. Deficiency of the cytoskeletal protein SPECC1L leads to oblique facial clefting. American Journal of Human Genetics. 89: 44-55. PMID 21703590 DOI: 10.1016/J.Ajhg.2011.05.023  0.329
2011 North TE, Goessling W. Endoderm specification, liver development, and regeneration. Methods in Cell Biology. 101: 205-23. PMID 21550446 DOI: 10.1016/B978-0-12-387036-0.00010-4  0.33
2011 Goessling W, Allen RS, Guan X, Jin P, Uchida N, Dovey M, Harris JM, Metzger ME, Bonifacino AC, Stroncek D, Stegner J, Armant M, Schlaeger T, Tisdale JF, Zon LI, et al. Prostaglandin E2 enhances human cord blood stem cell xenotransplants and shows long-term safety in preclinical nonhuman primate transplant models. Cell Stem Cell. 8: 445-58. PMID 21474107 DOI: 10.1016/J.Stem.2011.02.003  0.312
2011 Carroll KJ, Dovey MC, Cutting CC, Sheward LV, Harris JM, Goessling W, North TE. Hematopoietic Stem Cell Formation in Zebrafish Is Regulated in a Temporally Distinct Manner by Estrogen Receptor 2 Blood. 118: 1268-1268. DOI: 10.1182/Blood.V118.21.1268.1268  0.396
2011 Harris JM, Harris LJ, Cox AG, Garnaas MK, Frechette GM, Cortes M, Cutting CC, Dovey MC, Paw BH, Heiden MV, Goessling W, North TE. Metabolism-Induced Reactive Oxygen Species and Hif1α-Mediated Gene Regulation Control the Timing and Magnitude of Hematopoietic Stem Cell Induction Blood. 118: 1266-1266. DOI: 10.1182/Blood.V118.21.1266.1266  0.741
2011 Cutler C, Desponts C, Robbins D, North T, Goessling W, Kao G, Ritz J, Ballen K, Antin J, Spitzer T, SoifferChenY.-B.A. R, Ho V, Armand P, Koreth J, Alyea E, et al. Ex Vivo Treatment of Hematopoietic Stem Cells With 16,16-Dimethyl Prostaglandin E2 (FT1050) Improves Engraftment and Hematopoietic Reconstitution Biology of Blood and Marrow Transplantation. 17: S226. DOI: 10.1016/J.Bbmt.2010.12.224  0.305
2010 North TE, Babu IR, Vedder LM, Lord AM, Wishnok JS, Tannenbaum SR, Zon LI, Goessling W. PGE2-regulated wnt signaling and N-acetylcysteine are synergistically hepatoprotective in zebrafish acetaminophen injury. Proceedings of the National Academy of Sciences of the United States of America. 107: 17315-20. PMID 20855591 DOI: 10.1073/Pnas.1008209107  0.34
2010 Wang Y, Krivtsov AV, Sinha AU, North TE, Goessling W, Feng Z, Zon LI, Armstrong SA. The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML. Science (New York, N.Y.). 327: 1650-3. PMID 20339075 DOI: 10.1126/Science.1186624  0.323
2010 Baba Y, Nosho K, Shima K, Goessling W, Chan AT, Ng K, Chan JA, Giovannucci EL, Fuchs CS, Ogino S. PTGER2 overexpression in colorectal cancer is associated with microsatellite instability, independent of CpG island methylator phenotype. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 19: 822-31. PMID 20200425 DOI: 10.1158/1055-9965.Epi-09-1154  0.308
2010 Harris JM, Harris LJ, Dovey MC, Cutting CC, Paw BH, Heiden MGV, Goessling W, North TE. Glucose Catabolism with Resultant Formation of Reactive Oxygen Species and Local Hypoxia Modulates the Induction and Expansion of Hematopoietic Stem Cells Blood. 116: 408-408. DOI: 10.1182/Blood.V116.21.408.408  0.342
2010 Carroll KJ, Dovey MC, Cutting CC, Harris JM, Vedder LM, Goessling W, North TE. Estrogen Receptors 1 and 2 Have Stage-Specific Effects on Hematopoietic Stem Cell Regulation In Zebrafish. Blood. 116: 1617-1617. DOI: 10.1182/Blood.V116.21.1617.1617  0.392
2009 North TE, Goessling W, Peeters M, Li P, Ceol C, Lord AM, Weber GJ, Harris J, Cutting CC, Huang P, Dzierzak E, Zon LI. Hematopoietic stem cell development is dependent on blood flow. Cell. 137: 736-48. PMID 19450519 DOI: 10.1016/J.Cell.2009.04.023  0.342
2009 Dovey M, Patton EE, Bowman T, North T, Goessling W, Zhou Y, Zon LI. Topoisomerase II alpha is required for embryonic development and liver regeneration in zebrafish. Molecular and Cellular Biology. 29: 3746-53. PMID 19380487 DOI: 10.1128/Mcb.01684-08  0.341
2009 Goessling W, North TE, Loewer S, Lord AM, Lee S, Stoick-Cooper CL, Weidinger G, Puder M, Daley GQ, Moon RT, Zon LI. Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regeneration. Cell. 136: 1136-47. PMID 19303855 DOI: 10.1016/J.Cell.2009.01.015  0.379
2009 Wang Y, Krivtsov AV, Sinha AU, North T, Goessling W, Zon LI, Armstrong S. β-Catenin Determines Developmental Stage Specific Transformation by Hox Genes. Blood. 114: 385-385. DOI: 10.1182/Blood.V114.22.385.385  0.309
2009 Goessling W, Guan X, Dovey M, Stegner J, Armant M, Schlaeger T, Zon LI, North T. Human Umbilical Cord Blood Stem Cell Function Is Augmented by Exposure to Prostaglandin E2. Blood. 114: 369-369. DOI: 10.1182/Blood.V114.22.369.369  0.339
2009 Allen RS, Jin P, North T, Goessling W, Tian Y, Metzger ME, Bonifacino AC, Stroncek D, Zon LI, Donahue RE. Global Gene Expression Signatures in CD34+ Hematopoietic Cells Following Exposure to 16,16-Dimethylprostaglandin E2. Blood. 114: 2523-2523. DOI: 10.1182/Blood.V114.22.2523.2523  0.365
2009 Harris J, Cutting CC, Dovey M, Goessling W, North T. Metabolic Endocrine Regulators of Hematopoietic Stem Cell Formation and Function. Blood. 114: 1496-1496. DOI: 10.1182/Blood.V114.22.1496.1496  0.331
2008 Goessling W, North TE, Lord AM, Ceol C, Lee S, Weidinger G, Bourque C, Strijbosch R, Haramis AP, Puder M, Clevers H, Moon RT, Zon LI. APC mutant zebrafish uncover a changing temporal requirement for wnt signaling in liver development. Developmental Biology. 320: 161-74. PMID 18585699 DOI: 10.1016/J.Ydbio.2008.05.526  0.39
2008 White RM, Sessa A, Burke C, Bowman T, LeBlanc J, Ceol C, Bourque C, Dovey M, Goessling W, Burns CE, Zon LI. Transparent adult zebrafish as a tool for in vivo transplantation analysis. Cell Stem Cell. 2: 183-9. PMID 18371439 DOI: 10.1016/J.Stem.2007.11.002  0.31
2008 North TE, Goessling W, Peeters M, Li P, Lord AM, Dzierzak E, Zon LI. Hematopoietic Stem Cell Development Is Dependent on Blood Flow and Nitric Oxide Signaling Blood. 112: 728-728. DOI: 10.1182/Blood.V112.11.728.728  0.349
2007 North TE, Goessling W, Walkley CR, Lengerke C, Kopani KR, Lord AM, Weber GJ, Bowman TV, Jang IH, Grosser T, Fitzgerald GA, Daley GQ, Orkin SH, Zon LI. Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis. Nature. 447: 1007-11. PMID 17581586 DOI: 10.1038/Nature05883  0.388
2007 Langenau DM, Keefe MD, Storer NY, Guyon JR, Kutok JL, Le X, Goessling W, Neuberg DS, Kunkel LM, Zon LI. Effects of RAS on the genesis of embryonal rhabdomyosarcoma. Genes & Development. 21: 1382-95. PMID 17510286 DOI: 10.1101/Gad.1545007  0.337
2007 North TE, Goessling W, Armant M, Kao GS, Silberstein LE, Ritz J, Zon LI. Ex Vivo Treatment of Human Cord Blood with dmPGE2 Can Safely Increase the Potential for Hematopoietic Engraftment. Blood. 110: 1190-1190. DOI: 10.1182/Blood.V110.11.1190.1190  0.339
2007 North TE, Goessling W, Kopani KR, Mayhall E, Jang I, Lengerke C, Burns CE, Lord A, Grosser T, FitzGerald GA, Daley GQ, Zon LI. A high-throughput chemical genetic screen in zebrafish establishes that prostaglandin E2 is a potent regulator of hematopoietic stem cell formation Blood Cells, Molecules, and Diseases. 38: 191. DOI: 10.1016/J.Bcmd.2006.10.159  0.339
2006 North TE, Goessling W, Kopani KR, Lengerke C, Walkley CR, Lord AM, Jang I, Grosser T, FitzGerald GA, Daley GQ, Orkin SH, Zon LI. Prostaglandin E2 Is a Potent Regulator of Vertebrate Hematopoietic Stem Cell Homeostasis. Blood. 108: 680-680. DOI: 10.1182/Blood.V108.11.680.680  0.395
1996 Zucker SD, Goessling W, Gollan JL. Intracellular transport of small hydrophobic compounds by the hepatocyte Seminars in Liver Disease. 16: 159-167. PMID 8781021 DOI: 10.1055/S-2007-1007229  0.313
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