| Year |
Citation |
Score |
| 2022 |
Bariana M, Cassella E, Rateshwar J, Ouk S, Liou HC, Heller C, Colorado I, Feinman R, Makhdoom A, Siegel DS, Heller G, Tuckett A, Mondello P, Zakrzewski JL. Inhibition of NF-κB DNA binding suppresses myeloma growth via intracellular redox and tumor microenvironment modulation. Molecular Cancer Therapeutics. PMID 36190955 DOI: 10.1158/1535-7163.MCT-22-0257 |
0.343 |
|
| 2017 |
Vaisitti T, Gaudino F, Ouk S, Moscvin M, Vitale N, Serra S, Arruga F, Zakrzewski JL, Liou HC, Allan JN, Furman RR, Deaglio S. Targeting metabolism and survival in chronic lymphocytic leukemia and Richter syndrome cells by a novel NF-kB inhibitor. Haematologica. PMID 28860341 DOI: 10.3324/Haematol.2017.173419 |
0.478 |
|
| 2016 |
Shono Y, Tuckett AZ, Liou HC, Doubrovina E, Derenzini E, Ouk S, Tsai JJ, Smith OM, Levy ER, Kreines FM, Ziegler CG, Scallion MI, Doubrovin M, Heller G, Younes A, et al. Characterization of a c-Rel Inhibitor That Mediates Anticancer Properties in Hematologic Malignancies by Blocking NF-κB-Controlled Oxidative Stress Responses. Cancer Research. 76: 377-89. PMID 26744524 DOI: 10.1158/0008-5472.Can-14-2814 |
0.438 |
|
| 2016 |
Vaisitti T, Gaudino F, Ouk S, Serra S, Zakrzewski JL, Bhavsar EB, Allan JN, Liou H, Furman RR, Deaglio S. Targeting Cellular Metabolism and Survival in Chronic Lymphocytic Leukemia and Richter Syndrome Cells By a Novel NF-Kb Inhibitor Blood. 128: 304-304. DOI: 10.1182/Blood.V128.22.304.304 |
0.542 |
|
| 2014 |
Shono Y, Tuckett AZ, Ouk S, Liou HC, Altan-Bonnet G, Tsai JJ, Oyler JE, Smith OM, West ML, Singer NV, Doubrovina E, Pankov D, Undhad CV, Murphy GF, Lezcano C, et al. A small-molecule c-Rel inhibitor reduces alloactivation of T cells without compromising antitumor activity. Cancer Discovery. 4: 578-91. PMID 24550032 DOI: 10.1158/2159-8290.Cd-13-0585 |
0.533 |
|
| 2014 |
Shono Y, Tuckett AZ, Liou H, Ouk S, Doubrovina E, Doubrovin M, Derenzini E, Scallion MI, Tsai JJ, Smith OM, Younes A, O'Reilly RJ, van den Brink MR, Zakrzewski JL. Targeted Therapy of B Cell Lymphoma with a Direct Inhibitor of the NF-κB Subunit c-Rel Blood. 124: 507-507. DOI: 10.1182/Blood.V124.21.507.507 |
0.627 |
|
| 2013 |
Boopathi E, Hypolite JA, Zderic SA, Gomes CM, Malkowicz B, Liou HC, Wein AJ, Chacko S. GATA-6 and NF-κB activate CPI-17 gene transcription and regulate Ca2+ sensitization of smooth muscle contraction. Molecular and Cellular Biology. 33: 1085-102. PMID 23275439 DOI: 10.1128/MCB.00626-12 |
0.302 |
|
| 2013 |
Shono Y, Tuckett AZ, Liou H, Altan-Bonnet G, Tsai JJ, Smith OM, West ML, Singer NV, Brink MRMvd, Zakrzewski JL. Inhibition of c-Rel Activity Prevents Graft-Versus-Host Disease without Compromising Tumor Immunity Biology of Blood and Marrow Transplantation. 19. DOI: 10.1016/J.Bbmt.2012.11.023 |
0.309 |
|
| 2012 |
Shono Y, Tuckett A, Liou H, Atlan-Bonnet G, Tsai JJ, Smith OM, West ML, Singer NV, Brink MRMvd, Zakrzewski J. Inhibition of c-Rel Signaling: A Novel Small Molecule-Based Therapy Diminishing T Cell Alloactivation While Preserving Anti-Tumor Activity Blood. 120: 454-454. DOI: 10.1182/Blood.V120.21.454.454 |
0.539 |
|
| 2011 |
Ruan Q, Kameswaran V, Zhang Y, Zheng S, Sun J, Wang J, DeVirgiliis J, Liou HC, Beg AA, Chen YH. The Th17 immune response is controlled by the Rel-RORγ-RORγ T transcriptional axis. The Journal of Experimental Medicine. 208: 2321-33. PMID 22006976 DOI: 10.1084/Jem.20110462 |
0.307 |
|
| 2011 |
Liou HC, Smith KA. The roles of c-rel and interleukin-2 in tolerance: a molecular explanation of self-nonself discrimination. Immunology and Cell Biology. 89: 27-32. PMID 20975733 DOI: 10.1038/icb.2010.120 |
0.455 |
|
| 2010 |
Jordan KA, Dupont CD, Tait ED, Liou HC, Hunter CA. Role of the NF-κB transcription factor c-Rel in the generation of CD8+ T-cell responses to Toxoplasma gondii. International Immunology. 22: 851-61. PMID 21118906 DOI: 10.1093/Intimm/Dxq439 |
0.529 |
|
| 2010 |
Gieling RG, Elsharkawy AM, Caamaño JH, Cowie DE, Wright MC, Ebrahimkhani MR, Burt AD, Mann J, Raychaudhuri P, Liou HC, Oakley F, Mann DA. The c-Rel subunit of nuclear factor-kappaB regulates murine liver inflammation, wound-healing, and hepatocyte proliferation. Hepatology (Baltimore, Md.). 51: 922-31. PMID 20058312 DOI: 10.1002/Hep.23385 |
0.466 |
|
| 2009 |
Ouk S, Liou ML, Liou HC. Direct Rel/NF-κB inhibitors: structural basis for mechanism of action. Future Medicinal Chemistry. 1: 1683-707. PMID 21425986 DOI: 10.4155/Fmc.09.96 |
0.364 |
|
| 2009 |
Ruan Q, Kameswaran V, Tone Y, Li L, Liou HC, Greene MI, Tone M, Chen YH. Development of Foxp3(+) regulatory t cells is driven by the c-Rel enhanceosome. Immunity. 31: 932-40. PMID 20064450 DOI: 10.1016/J.Immuni.2009.10.006 |
0.475 |
|
| 2009 |
Tian W, Liou HC. RNAi-mediated c-Rel silencing leads to apoptosis of B cell tumor cells and suppresses antigenic immune response in vivo. Plos One. 4: e5028. PMID 19347041 DOI: 10.1371/journal.pone.0005028 |
0.569 |
|
| 2009 |
Cheng S, Hsia CY, Feng B, Liou ML, Fang X, Pandolfi PP, Liou HC. BCR-mediated apoptosis associated with negative selection of immature B cells is selectively dependent on Pten. Cell Research. 19: 196-207. PMID 18781138 DOI: 10.1038/Cr.2008.284 |
0.813 |
|
| 2007 |
Carmody RJ, Ruan Q, Liou HC, Chen YH. Essential roles of c-Rel in TLR-induced IL-23 p19 gene expression in dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 178: 186-91. PMID 17182554 DOI: 10.4049/Jimmunol.178.1.186 |
0.459 |
|
| 2007 |
Judge AR, Koncarevic A, Hunter RB, Liou HC, Jackman RW, Kandarian SC. Role for IkappaBalpha, but not c-Rel, in skeletal muscle atrophy. American Journal of Physiology. Cell Physiology. 292: C372-82. PMID 16928772 DOI: 10.1152/Ajpcell.00293.2006 |
0.321 |
|
| 2006 |
Yang Y, Liou HC, Sun XH. Id1 potentiates NF-kappaB activation upon T cell receptor signaling. The Journal of Biological Chemistry. 281: 34989-96. PMID 17012234 DOI: 10.1074/jbc.M608078200 |
0.416 |
|
| 2006 |
O'Riordan KJ, Huang IC, Pizzi M, Spano P, Boroni F, Egli R, Desai P, Fitch O, Malone L, Ahn HJ, Liou HC, Sweatt JD, Levenson JM. Regulation of nuclear factor kappaB in the hippocampus by group I metabotropic glutamate receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 4870-9. PMID 16672661 DOI: 10.1523/Jneurosci.4527-05.2006 |
0.351 |
|
| 2006 |
Tato CM, Mason N, Artis D, Shapira S, Caamano JC, Bream JH, Liou HC, Hunter CA. Opposing roles of NF-κB family members in the regulation of NK cell proliferation and production of IFN-γ International Immunology. 18: 505-513. PMID 16481345 DOI: 10.1093/Intimm/Dxh391 |
0.408 |
|
| 2005 |
Banerjee D, Liou HC, Sen R. c-Rel-dependent priming of naive T cells by inflammatory cytokines. Immunity. 23: 445-58. PMID 16226509 DOI: 10.1016/j.immuni.2005.09.012 |
0.438 |
|
| 2005 |
Tian W, Feng B, Liou HC. Silencing OCILRP2 leads to intrinsic defects in T cells in response to antigenic stimulation. Cellular Immunology. 235: 72-84. PMID 16143319 DOI: 10.1016/J.Cellimm.2005.07.004 |
0.476 |
|
| 2005 |
Corn RA, Hunter C, Liou HC, Siebenlist U, Boothby MR. Opposing roles for RelB and Bcl-3 in regulation of T-box expressed in T cells, GATA-3, and Th effector differentiation. Journal of Immunology (Baltimore, Md. : 1950). 175: 2102-10. PMID 16081776 DOI: 10.4049/Jimmunol.175.4.2102 |
0.479 |
|
| 2005 |
Tian W, Nunez R, Cheng S, Ding Y, Tumang J, Lyddane C, Roman C, Liou HC. C-type lectin OCILRP2/Clr-g and its ligand NKRP1f costimulate T cell proliferation and IL-2 production. Cellular Immunology. 234: 39-53. PMID 15963483 DOI: 10.1016/J.Cellimm.2005.04.021 |
0.771 |
|
| 2004 |
Feng B, Cheng S, Hsia CY, King LB, Monroe JG, Liou HC. NF-kappaB inducible genes BCL-X and cyclin E promote immature B-cell proliferation and survival. Cellular Immunology. 232: 9-20. PMID 15922711 DOI: 10.1016/J.Cellimm.2005.01.006 |
0.837 |
|
| 2004 |
Huang X, Di Liberto M, Cunningham AF, Kang L, Cheng S, Ely S, Liou HC, Maclennan IC, Chen-Kiang S. Homeostatic cell-cycle control by BLyS: Induction of cell-cycle entry but not G1/S transition in opposition to p18INK4c and p27Kip1. Proceedings of the National Academy of Sciences of the United States of America. 101: 17789-94. PMID 15591344 DOI: 10.1073/Pnas.0406111101 |
0.545 |
|
| 2004 |
Nuñez R, Fraefel C, Suter M, Nuñez-Liman A, Liou HC, Ackerman M. Assessment of a cellular vaccination approach consisting of crawling dendritic cells (CDCs) transduced with HSV-1-Deltapac vectors. Immunologic Research. 30: 105-24. PMID 15258314 DOI: 10.1385/Ir:30:1:105 |
0.433 |
|
| 2004 |
Feng B, Cheng S, Pear WS, Liou HC. NF-kB inhibitor blocks B cell development at two checkpoints. Medical Immunology (London, England). 3: 1. PMID 15050028 DOI: 10.1186/1476-9433-3-1 |
0.569 |
|
| 2004 |
Mason NJ, Liou HC, Hunter CA. T Cell-Intrinsic Expression of c-Rel Regulates Th1 Cell Responses Essential for Resistance to Toxoplasma gondii Journal of Immunology. 172: 3704-3711. PMID 15004174 DOI: 10.4049/Jimmunol.172.6.3704 |
0.425 |
|
| 2003 |
Cheng S, Hsia CY, Leone G, Liou HC. Cyclin E and Bcl-xL cooperatively induce cell cycle progression in c-Rel-/- B cells. Oncogene. 22: 8472-86. PMID 14627988 DOI: 10.1038/Sj.Onc.1206917 |
0.838 |
|
| 2003 |
Lamhamedi-Cherradi SE, Zheng S, Hilliard BA, Xu L, Sun J, Alsheadat S, Liou HC, Chen YH. Transcriptional regulation of type I diabetes by NF-kappa B. Journal of Immunology (Baltimore, Md. : 1950). 171: 4886-92. PMID 14568969 DOI: 10.4049/Jimmunol.171.9.4886 |
0.374 |
|
| 2003 |
Liou HC, Hsia CY. Distinctions between c-Rel and other NF-kappaB proteins in immunity and disease. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 25: 767-80. PMID 12879447 DOI: 10.1002/Bies.10306 |
0.806 |
|
| 2003 |
Hatada EN, Do RK, Orlofsky A, Liou HC, Prystowsky M, MacLennan IC, Caamano J, Chen-Kiang S. NF-kappa B1 p50 is required for BLyS attenuation of apoptosis but dispensable for processing of NF-kappa B2 p100 to p52 in quiescent mature B cells. Journal of Immunology (Baltimore, Md. : 1950). 171: 761-8. PMID 12847243 DOI: 10.4049/Jimmunol.171.2.761 |
0.54 |
|
| 2003 |
Boffa DJ, Feng B, Sharma V, Dematteo R, Miller G, Suthanthiran M, Nunez R, Liou HC. Selective loss of c-Rel compromises dendritic cell activation of T lymphocytes. Cellular Immunology. 222: 105-15. PMID 12826080 DOI: 10.1016/S0008-8749(03)00114-X |
0.54 |
|
| 2002 |
Liou HC. Regulation of the immune system by NF-kappaB and IkappaB. Journal of Biochemistry and Molecular Biology. 35: 537-46. PMID 12470586 |
0.316 |
|
| 2002 |
Finn PW, He H, Ma C, Mueller T, Stone JR, Liou HC, Boothby MR, Perkins DL. Molecular profiling of the role of the NF-kappaB family of transcription factors during alloimmunity. Journal of Leukocyte Biology. 72: 1054-62. PMID 12429729 |
0.379 |
|
| 2002 |
Tumang JR, Hsia CY, Tian W, Bromberg JF, Liou HC. IL-6 rescues the hyporesponsiveness of c-Rel deficient B cells independent of Bcl-xL, Mcl-1, and Bcl-2. Cellular Immunology. 217: 47-57. PMID 12426000 DOI: 10.1016/S0008-8749(02)00513-0 |
0.778 |
|
| 2002 |
Artis D, Shapira S, Mason N, Speirs KM, Goldschmidt M, Caamaño J, Liou HC, Hunter CA, Scott P. Differential requirement for NF-kappa B family members in control of helminth infection and intestinal inflammation. Journal of Immunology (Baltimore, Md. : 1950). 169: 4481-7. PMID 12370384 DOI: 10.4049/Jimmunol.169.8.4481 |
0.42 |
|
| 2002 |
Hilliard BA, Mason N, Xu L, Sun J, Lamhamedi-Cherradi SE, Liou HC, Hunter C, Chen YH. Critical roles of c-Rel in autoimmune inflammation and helper T cell differentiation. The Journal of Clinical Investigation. 110: 843-50. PMID 12235116 DOI: 10.1172/Jci15254 |
0.42 |
|
| 2002 |
Yang H, Thomas D, Boffa DJ, Ding R, Li B, Muthukumar T, Sharma VK, Lagman M, Luo GX, Kapur S, Liou HC, Hancock WW, Suthanthiran M. Enforced c-REL deficiency prolongs survival of islet allografts1. Transplantation. 74: 291-8. PMID 12177605 DOI: 10.1097/00007890-200208150-00002 |
0.455 |
|
| 2002 |
Hsia CY, Cheng S, Owyang AM, Dowdy SF, Liou HC. c-Rel regulation of the cell cycle in primary mouse B lymphocytes. International Immunology. 14: 905-16. PMID 12147627 DOI: 10.1093/Intimm/Dxf055 |
0.784 |
|
| 2002 |
Pizzi M, Goffi F, Boroni F, Benarese M, Perkins SE, Liou HC, Spano P. Opposing roles for NF-kappa B/Rel factors p65 and c-Rel in the modulation of neuron survival elicited by glutamate and interleukin-1beta. The Journal of Biological Chemistry. 277: 20717-23. PMID 11912207 DOI: 10.1074/jbc.M201014200 |
0.386 |
|
| 2002 |
Mason N, Aliberti J, Caamano JC, Liou HC, Hunter CA. Cutting edge: identification of c-Rel-dependent and -independent pathways of IL-12 production during infectious and inflammatory stimuli. Journal of Immunology (Baltimore, Md. : 1950). 168: 2590-4. PMID 11884420 DOI: 10.4049/Jimmunol.168.6.2590 |
0.418 |
|
| 2001 |
Bernal A, Pastore RD, Asgary Z, Keller SA, Cesarman E, Liou HC, Schattner EJ. Survival of leukemic B cells promoted by engagement of the antigen receptor. Blood. 98: 3050-7. PMID 11698290 DOI: 10.1182/Blood.V98.10.3050 |
0.571 |
|
| 2001 |
Owyang AM, Tumang JR, Schram BR, Hsia CY, Behrens TW, Rothstein TL, Liou HC. c-Rel is required for the protection of B cells from antigen receptor-mediated, but not Fas-mediated, apoptosis. Journal of Immunology (Baltimore, Md. : 1950). 167: 4948-56. PMID 11673501 DOI: 10.4049/Jimmunol.167.9.4948 |
0.769 |
|
| 2000 |
Sanjabi S, Hoffmann A, Liou HC, Baltimore D, Smale ST. Selective requirement for c-Rel during IL-12 P40 gene induction in macrophages. Proceedings of the National Academy of Sciences of the United States of America. 97: 12705-10. PMID 11058167 DOI: 10.1073/Pnas.230436397 |
0.412 |
|
| 2000 |
Andjelic S, Hsia C, Suzuki H, Kadowaki T, Koyasu S, Liou HC. Phosphatidylinositol 3-kinase and NF-kappa B/Rel are at the divergence of CD40-mediated proliferation and survival pathways. Journal of Immunology (Baltimore, Md. : 1950). 165: 3860-7. PMID 11034392 DOI: 10.4049/Jimmunol.165.7.3860 |
0.779 |
|
| 2000 |
Park YC, Ye H, Hsia C, Segal D, Rich RL, Liou HC, Myszka DG, Wu H. A novel mechanism of TRAF signaling revealed by structural and functional analyses of the TRADD-TRAF2 interaction. Cell. 101: 777-87. PMID 10892748 DOI: 10.1016/S0092-8674(00)80889-2 |
0.77 |
|
| 2000 |
Furman RR, Asgary Z, Mascarenhas JO, Liou H, Schattner EJ. Modulation of NF-κB Activity and Apoptosis in Chronic Lymphocytic Leukemia B Cells Journal of Immunology. 164: 2200-2206. PMID 10657675 DOI: 10.4049/Jimmunol.164.4.2200 |
0.5 |
|
| 1999 |
Liou HC, Jin Z, Tumang J, Andjelic S, Smith KA, Liou ML. c-Rel is crucial for lymphocyte proliferation but dispensable for T cell effector function. International Immunology. 11: 361-71. PMID 10221648 DOI: 10.1093/Intimm/11.3.361 |
0.783 |
|
| 1998 |
Tumang JR, Owyang A, Andjelic S, Jin Z, Hardy RR, Liou ML, Liou HC. c-Rel is essential for B lymphocyte survival and cell cycle progression. European Journal of Immunology. 28: 4299-312. PMID 9862367 DOI: 10.1002/(Sici)1521-4141(199812)28:12<4299::Aid-Immu4299>3.0.Co;2-Y |
0.825 |
|
| 1998 |
Andjelic S, Liou H. Antigen receptor-induced B lymphocyte apoptosis mediated via a protease of the caspase family. European Journal of Immunology. 28: 570-581. PMID 9521067 DOI: 10.1002/(Sici)1521-4141(199802)28:02<570::Aid-Immu570>3.0.Co;2-M |
0.534 |
|
| 1995 |
Sha WC, Liou HC, Tuomanen EI, Baltimore D. Targeted disruption of the p50 subunit of NF-κB leads to multifocal defects in immune responses Cell. 80: 321-330. PMID 7834752 DOI: 10.1016/0092-8674(95)90415-8 |
0.428 |
|
| 1991 |
Ono SJ, Liou HC, Davidon R, Strominger JL, Glimcher LH. Human X-box-binding protein 1 is required for the transcription of a subset of human class II major histocompatibility genes and forms a heterodimer with c-fos Proceedings of the National Academy of Sciences of the United States of America. 88: 4309-4312. PMID 1903538 DOI: 10.1073/Pnas.88.10.4309 |
0.381 |
|
| 1991 |
Davis N, Ghosh S, Simmons DL, Tempst P, Liou HC, Baltimore D, Bose HR. Rel-associated pp40: an inhibitor of the rel family of transcription factors. Science (New York, N.Y.). 253: 1268-71. PMID 1891714 DOI: 10.1126/Science.1891714 |
0.45 |
|
| 1991 |
Liou HC, Eddy R, Shows T, Lisowska-Grospierre B, Griscelli C, Doyle C, Mannhalter J, Eibl M, Glimcher LH. An HLA-DR alpha promoter DNA-binding protein is expressed ubiquitously and maps to human chromosomes 22 and 5. Immunogenetics. 34: 286-92. PMID 1718857 DOI: 10.1007/Bf00211992 |
0.32 |
|
| 1990 |
Liou HC, Boothby MR, Finn PW, Davidon R, Nabavi N, Zeleznik-Le NJ, Ting JP, Glimcher LH. A new member of the leucine zipper class of proteins that binds to the HLA DR alpha promoter. Science (New York, N.Y.). 247: 1581-4. PMID 2321018 DOI: 10.1126/Science.2321018 |
0.366 |
|
| 1990 |
Kara CJ, Liou HC, Ivashkiv LB, Glimcher LH. A cDNA for a human cyclic AMP response element-binding protein which is distinct from CREB and expressed preferentially in brain Molecular and Cellular Biology. 10: 1347-1357. PMID 2320002 DOI: 10.1128/Mcb.10.4.1347 |
0.363 |
|
| 1990 |
Boothby M, Liou HC, Finn PW, Gravallese E, Glimcher LH. Control of transcription at the murine Aα locus Immunologic Research. 9: 77-92. PMID 2189937 DOI: 10.1007/Bf02918199 |
0.379 |
|
| 1990 |
Ivashkiv LB, Liou HC, Kara CJ, Lamph WW, Verma IM, Glimcher LH. mXBP/CRE-BP2 and c-Jun form a complex which binds to the cyclic AMP, but not to the 12-O-tetradecanoylphorbol-13-acetate, response element. Molecular and Cellular Biology. 10: 1609-21. PMID 2138707 DOI: 10.1128/Mcb.10.4.1609 |
0.399 |
|
| 1988 |
Liou HC, Boothby MR, Glimcher LH. Distinct cloned class II MHC DNA binding proteins recognize the X box transcription element Science. 242: 69-71. PMID 3140376 DOI: 10.1126/Science.3140376 |
0.305 |
|
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