| Year |
Citation |
Score |
| 2023 |
Uccello TP, Lesch ML, Kintzel SA, Gradzewicz LB, Lamrous L, Murphy SP, Fleming FJ, Mills BN, Murphy JD, Hughson A, Hannon G, Garrett-Larsen J, Qiu H, Drage MG, Ye J, ... ... Lord EM, et al. New insights into the responder/nonresponder divide in rectal cancer: Damage-induced Type I IFNs dictate treatment efficacy and can be targeted to enhance radiotherapy. Cell Death & Disease. 14: 470. PMID 37495596 DOI: 10.1038/s41419-023-05999-3 |
0.3 |
|
| 2023 |
Gerber S, Uccello T, Lesch M, Kintzel S, Gradzewicz L, Lamrous L, Murphy S, Fleming F, Mills B, Murphy J, Hughson A, Garrett-Larsen J, Qiu H, Drage M, Ye J, ... ... Lord E, et al. New insights into the responder/nonresponder divide in rectal cancer: Damage-induced Type I IFNs dictate treatment efficacy and can be targeted to enhance radiotherapy. Research Square. PMID 37090639 DOI: 10.21203/rs.3.rs-2767780/v1 |
0.3 |
|
| 2022 |
Ye J, Mills BN, Qin SS, Garrett-Larsen J, Murphy JD, Uccello TP, Han BJ, Vrooman TG, Johnston CJ, Lord EM, Belt BA, Linehan DC, Gerber SA. Toll-like receptor 7/8 agonist R848 alters the immune tumor microenvironment and enhances SBRT-induced antitumor efficacy in murine models of pancreatic cancer. Journal For Immunotherapy of Cancer. 10. PMID 35851308 DOI: 10.1136/jitc-2022-004784 |
0.313 |
|
| 2022 |
Battaglia NG, Murphy JD, Uccello TP, Hughson A, Gavras NW, Caldon JJ, Gerber SA, Lord EM. Combination of NKG2A and PD-1 Blockade Improves Radiotherapy Response in Radioresistant Tumors. Journal of Immunology (Baltimore, Md. : 1950). PMID 35840162 DOI: 10.4049/jimmunol.2100044 |
0.354 |
|
| 2022 |
Ortiz-Bonilla CJ, Uccello TP, Gerber SA, Lord EM, Messing EM, Lee YF. Bladder Cancer Extracellular Vesicles Elicit a CD8 T Cell-Mediated Antitumor Immunity. International Journal of Molecular Sciences. 23. PMID 35328324 DOI: 10.3390/ijms23062904 |
0.397 |
|
| 2021 |
Mills BN, Qiu H, Drage MG, Chen C, Mathew JS, Garrett-Larsen J, Ye J, Uccello TP, Murphy JD, Belt BA, Lord EM, Katz AW, Linehan DC, Gerber SA. Modulation of the Human Pancreatic Ductal Adenocarcinoma Immune Microenvironment by Stereotactic Body Radiotherapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 34862242 DOI: 10.1158/1078-0432.CCR-21-2495 |
0.319 |
|
| 2021 |
Qin SS, Han BJ, Williams A, Jackson KM, Jewell R, Chacon AC, Lord EM, Linehan DC, Kim M, Reuben A, Gerber SA, Prieto PA. Intertumoral Genetic Heterogeneity Generates Distinct Tumor Microenvironments in a Novel Murine Synchronous Melanoma Model. Cancers. 13. PMID 34064795 DOI: 10.3390/cancers13102293 |
0.3 |
|
| 2021 |
Battaglia NG, Uccello TP, Hughson A, Garrett-Larsen J, Caldon JJ, Qiu H, Gerber SA, Lord EM. Co-administration of a clinically relevant dexamethasone dosage with ablative radiotherapy reduces peripheral lymphocytes but does not alter in vivo intratumoral lymphocyte phenotype or inhibit efficacy of radiotherapy in a murine colorectal tumor model. International Journal of Radiation Oncology, Biology, Physics. PMID 33933481 DOI: 10.1016/j.ijrobp.2021.04.021 |
0.347 |
|
| 2020 |
Han BJ, Murphy JD, Qin S, Ye J, Uccello TP, Garrett-Larsen J, Belt BA, Prieto PA, Egilmez NK, Lord EM, Linehan DC, Mills BN, Gerber SA. Microspheres Encapsulating Immunotherapy Agents Target the Tumor-Draining Lymph Node in Pancreatic Ductal Adenocarcinoma. Immunological Investigations. 1-16. PMID 32498585 DOI: 10.1080/08820139.2020.1765795 |
0.402 |
|
| 2019 |
Ye J, Mills BN, Zhao T, Han BJ, Murphy JD, Patel AP, Johnston CJ, Lord EM, Belt BA, Linehan DC, Gerber SA. Assessing the magnitude of immunogenic cell death following chemotherapy and irradiation reveals a new strategy to treat pancreatic cancer. Cancer Immunology Research. PMID 31719057 DOI: 10.1158/2326-6066.Cir-19-0373 |
0.423 |
|
| 2019 |
Mills BN, Connolly KA, Ye J, Murphy JD, Uccello TP, Han BJ, Zhao T, Drage MG, Murthy A, Qiu H, Patel A, Figueroa NM, Johnston CJ, Prieto PA, Egilmez NK, ... ... Lord EM, et al. Stereotactic Body Radiation and Interleukin-12 Combination Therapy Eradicates Pancreatic Tumors by Repolarizing the Immune Microenvironment. Cell Reports. 29: 406-421.e5. PMID 31597100 DOI: 10.1016/J.Celrep.2019.08.095 |
0.403 |
|
| 2019 |
Murthy A, Gerber SA, Koch CJ, Lord EM. Intratumoral Hypoxia Reduces IFN-γ-Mediated Immunity and MHC Class I Induction in a Preclinical Tumor Model. Immunohorizons. 3: 149-160. PMID 31356176 DOI: 10.4049/immunohorizons.1900017 |
0.42 |
|
| 2019 |
MacDonald CR, Bucsek MJ, Qiao G, Chen M, Evans L, Greenberg DJ, Uccello TP, Battaglia NG, Hylander BL, Singh AK, Lord EM, Gerber SA, Repasky EA. Adrenergic Receptor Signaling Regulates the Response of Tumors to Ionizing Radiation. Radiation Research. PMID 31021732 DOI: 10.1667/Rr15193.1 |
0.462 |
|
| 2016 |
Connolly KA, Belt BA, Figueroa NM, Murthy A, Patel A, Kim M, Lord EM, Linehan DC, Gerber SA. Increasing the efficacy of radiotherapy by modulating the CCR2/CCR5 chemokine axes. Oncotarget. PMID 27852031 DOI: 10.18632/Oncotarget.13287 |
0.49 |
|
| 2016 |
Barlow ML, Cummings RJ, Pentland AP, Love TM, Haidaris CG, Ryan JL, Lord EM, Gerber SA. Total-Body Irradiation Exacerbates Dissemination of Cutaneous Candida Albicans Infection. Radiation Research. PMID 27710703 DOI: 10.1667/Rr14295.1 |
0.326 |
|
| 2014 |
Lim JY, Brockstedt DG, Lord EM, Gerber SA. Radiation therapy combined with Listeria monocytogenes-based cancer vaccine synergize to enhance tumor control in the B16 melanoma model. Oncoimmunology. 3: e29028. PMID 25083327 DOI: 10.4161/Onci.29028 |
0.455 |
|
| 2014 |
Haynes-Gilmore N, Banach M, Edholm ES, Lord E, Robert J. A critical role of non-classical MHC in tumor immune evasion in the amphibian Xenopus model. Carcinogenesis. 35: 1807-13. PMID 24776220 DOI: 10.1093/Carcin/Bgu100 |
0.485 |
|
| 2014 |
Xu Y, Hyun YM, Lim K, Lee H, Cummings RJ, Gerber SA, Bae S, Cho TY, Lord EM, Kim M. Optogenetic control of chemokine receptor signal and T-cell migration. Proceedings of the National Academy of Sciences of the United States of America. 111: 6371-6. PMID 24733886 DOI: 10.1073/Pnas.1319296111 |
0.41 |
|
| 2014 |
Lim JY, Gerber SA, Murphy SP, Lord EM. Type I interferons induced by radiation therapy mediate recruitment and effector function of CD8(+) T cells. Cancer Immunology, Immunotherapy : Cii. 63: 259-71. PMID 24357146 DOI: 10.1007/S00262-013-1506-7 |
0.449 |
|
| 2014 |
Majumder S, Sowden MP, Gerber SA, Thomas T, Christie CK, Mohan A, Yin G, Lord EM, Berk BC, Pang J. G-protein-coupled receptor-2-interacting protein-1 is required for endothelial cell directional migration and tumor angiogenesis via cortactin-dependent lamellipodia formation. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 419-26. PMID 24265417 DOI: 10.1161/Atvbaha.113.302689 |
0.386 |
|
| 2014 |
Gerber SA, Lim JY, Connolly KA, Sedlacek AL, Barlow ML, Murphy SP, Egilmez NK, Lord EM. Radio-responsive tumors exhibit greater intratumoral immune activity than nonresponsive tumors. International Journal of Cancer. Journal International Du Cancer. 134: 2383-92. PMID 24154990 DOI: 10.1002/Ijc.28558 |
0.497 |
|
| 2013 |
Sedlacek AL, Gerber SA, Randall TD, van Rooijen N, Frelinger JG, Lord EM. Generation of a dual-functioning antitumor immune response in the peritoneal cavity. The American Journal of Pathology. 183: 1318-28. PMID 23933065 DOI: 10.1016/J.Ajpath.2013.06.030 |
0.498 |
|
| 2013 |
Yokota SJ, Facciponte JG, Kelleher RJ, Shultz LD, Loyall JL, Parsons RR, Odunsi K, Frelinger JG, Lord EM, Gerber SA, Balu-Iyer SV, Bankert RB. Changes in ovarian tumor cell number, tumor vasculature, and T cell function monitored in vivo using a novel xenograft model. Cancer Immunity. 13: 11. PMID 23885217 |
0.383 |
|
| 2013 |
Gerber SA, Sedlacek AL, Cron KR, Murphy SP, Frelinger JG, Lord EM. IFN-γ mediates the antitumor effects of radiation therapy in a murine colon tumor. The American Journal of Pathology. 182: 2345-54. PMID 23583648 DOI: 10.1016/J.Ajpath.2013.02.041 |
0.464 |
|
| 2013 |
Gerber SA, Sorensen EW, Sedlacek AL, Lim JY, Skrombolas D, Frelinger JG, Lord EM. Local expression of interleukin-2 by B16 melanoma cells results in decreased tumour growth and long-term tumour dormancy. Immunology. 138: 280-92. PMID 23198850 DOI: 10.1111/Imm.12037 |
0.403 |
|
| 2013 |
Lim JYH, Gerber SA, Lord EM. Abstract A95: Distinct roles of type I and type II interferons in radiation-induced antitumor immunity against B16 melanoma. Cancer Research. 73. DOI: 10.1158/1538-7445.Tumimm2012-A95 |
0.462 |
|
| 2012 |
Cummings RJ, Gerber SA, Judge JL, Ryan JL, Pentland AP, Lord EM. Exposure to ionizing radiation induces the migration of cutaneous dendritic cells by a CCR7-dependent mechanism. Journal of Immunology (Baltimore, Md. : 1950). 189: 4247-57. PMID 23002435 DOI: 10.4049/Jimmunol.1201371 |
0.378 |
|
| 2012 |
Croy BA, Chen Z, Hofmann AP, Lord EM, Sedlacek AL, Gerber SA. Imaging of vascular development in early mouse decidua and its association with leukocytes and trophoblasts. Biology of Reproduction. 87: 125. PMID 22954796 DOI: 10.1095/Biolreprod.112.102830 |
0.332 |
|
| 2011 |
Valentino MD, Abdul-Alim CS, Maben ZJ, Skrombolas D, Hensley LL, Kawula TH, Dziejman M, Lord EM, Frelinger JA, Frelinger JG. A broadly applicable approach to T cell epitope identification: application to improving tumor associated epitopes and identifying epitopes in complex pathogens. Journal of Immunological Methods. 373: 111-26. PMID 21872603 DOI: 10.1016/J.Jim.2011.08.007 |
0.413 |
|
| 2011 |
Puskas J, Skrombolas D, Sedlacek A, Lord E, Sullivan M, Frelinger J. Development of an attenuated interleukin-2 fusion protein that can be activated by tumour-expressed proteases. Immunology. 133: 206-20. PMID 21426339 DOI: 10.1111/J.1365-2567.2011.03428.X |
0.332 |
|
| 2010 |
Sorensen EW, Gerber SA, Frelinger JG, Lord EM. IL-12 suppresses vascular endothelial growth factor receptor 3 expression on tumor vessels by two distinct IFN-gamma-dependent mechanisms. Journal of Immunology (Baltimore, Md. : 1950). 184: 1858-66. PMID 20061409 DOI: 10.4049/Jimmunol.0903210 |
0.451 |
|
| 2009 |
Cummings RJ, Mitra S, Foster TH, Lord EM. Migration of skin dendritic cells in response to ionizing radiation exposure. Radiation Research. 171: 687-97. PMID 19580475 DOI: 10.1667/Rr1600.1 |
0.373 |
|
| 2009 |
Sorensen EW, Gerber SA, Sedlacek AL, Rybalko VY, Chan WM, Lord EM. Omental immune aggregates and tumor metastasis within the peritoneal cavity. Immunologic Research. 45: 185-94. PMID 19253004 DOI: 10.1007/S12026-009-8100-2 |
0.462 |
|
| 2008 |
Cummings RJ, Mitra S, Lord EM, Foster TH. Antibody-labeled fluorescence imaging of dendritic cell populations in vivo. Journal of Biomedical Optics. 13: 044041. PMID 19021368 DOI: 10.1117/1.2966122 |
0.349 |
|
| 2008 |
Lugade AA, Sorensen EW, Gerber SA, Moran JP, Frelinger JG, Lord EM. Radiation-induced IFN-gamma production within the tumor microenvironment influences antitumor immunity. Journal of Immunology (Baltimore, Md. : 1950). 180: 3132-9. PMID 18292536 DOI: 10.4049/Jimmunol.180.5.3132 |
0.717 |
|
| 2007 |
Santos K, Simon DA, Conway E, Bowers WJ, Mitra S, Foster TH, Lugade A, Lord EM, Federoff HJ, Dewhurst S, Frelinger JG. Spatial and temporal expression of herpes simplex virus type 1 amplicon-encoded genes: implications for their use as immunization vectors. Human Gene Therapy. 18: 93-105. PMID 17298238 DOI: 10.1089/Hum.2006.082 |
0.682 |
|
| 2007 |
Ramanayake T, Simon DA, Frelinger JG, Lord EM, Robert J. In vivo study of T-cell responses to skin alloantigens in Xenopus using a novel whole-mount immunohistology method. Transplantation. 83: 159-66. PMID 17264812 DOI: 10.1097/01.Tp.0000250562.35175.06 |
0.35 |
|
| 2006 |
Gerber SA, Rybalko VY, Bigelow CE, Lugade AA, Foster TH, Frelinger JG, Lord EM. Preferential attachment of peritoneal tumor metastases to omental immune aggregates and possible role of a unique vascular microenvironment in metastatic survival and growth. The American Journal of Pathology. 169: 1739-52. PMID 17071597 DOI: 10.2353/Ajpath.2006.051222 |
0.711 |
|
| 2005 |
Lugade AA, Moran JP, Gerber SA, Rose RC, Frelinger JG, Lord EM. Local radiation therapy of B16 melanoma tumors increases the generation of tumor antigen-specific effector cells that traffic to the tumor. Journal of Immunology (Baltimore, Md. : 1950). 174: 7516-23. PMID 15944250 DOI: 10.4049/Jimmunol.174.12.7516 |
0.735 |
|
| 2005 |
Gerber SA, Turner MJ, Lugade AA, Moran JP, Frelinger JG, Lord EM. Characterization of a lymph node within the mouse prostate: Detailed analysis using whole mount histology. The Prostate. 63: 105-16. PMID 15468173 DOI: 10.1002/Pros.20169 |
0.627 |
|
| 2003 |
Moran JP, Gerber SA, Martin CA, Frelinger JG, Lord EM. Transfection of the genes for interleukin-12 into the K1735 melanoma and the EMT6 mammary sarcoma murine cell lines reveals distinct mechanisms of antitumor activity. International Journal of Cancer. Journal International Du Cancer. 106: 690-8. PMID 12866028 DOI: 10.1002/Ijc.11284 |
0.451 |
|
| 2003 |
Gerber SA, Moran JP, Frelinger JG, Frelinger JA, Fenton BM, Lord EM. Mechanism of IL-12 mediated alterations in tumour blood vessel morphology: analysis using whole-tissue mounts. British Journal of Cancer. 88: 1453-61. PMID 12778077 DOI: 10.1038/Sj.Bjc.6600907 |
0.318 |
|
| 2002 |
Fisher TL, Nocera M, Willis RA, Turner MJ, Abdul Alim CS, Brown DM, Bourne PA, di Sant'Agnese PA, Messing EM, Lord EM, Frelinger JG. Generation of monoclonal antibodies specific for human kallikrein 2 (hK2) using hK2-expressing tumors. The Prostate. 51: 153-65. PMID 11967950 DOI: 10.1002/Pros.10071 |
0.308 |
|
| 2001 |
Willis RA, Bowers WJ, Turner MJ, Fisher TL, Abdul-Alim CS, Howard DF, Federoff HJ, Lord EM, Frelinger JG. Dendritic cells transduced with HSV-1 amplicons expressing prostate-specific antigen generate antitumor immunity in mice. Human Gene Therapy. 12: 1867-79. PMID 11589829 DOI: 10.1089/104303401753153929 |
0.443 |
|
| 2001 |
Turner MJ, Abdul-Alim CS, Willis RA, Fisher TL, Lord EM, Frelinger JG. T-cell antigen discovery (T-CAD) assay: a novel technique for identifying T cell epitopes. Journal of Immunological Methods. 256: 107-19. PMID 11516759 DOI: 10.1016/S0022-1759(01)00436-7 |
0.377 |
|
| 2001 |
Fenton BM, Lord EM, Paoni SF. Intravascular HBO(2) saturations, perfusion and hypoxia in spontaneous and transplanted tumor models. International Journal of Cancer. Journal International Du Cancer. 93: 693-8. PMID 11477580 DOI: 10.1002/Ijc.1401 |
0.413 |
|
| 2001 |
Brown DM, Fisher TL, Wei C, Frelinger JG, Lord EM. Tumours can act as adjuvants for humoral immunity. Immunology. 102: 486-97. PMID 11328383 DOI: 10.1046/J.1365-2567.2001.01213.X |
0.375 |
|
| 2001 |
Fenton BM, Lord EM, Paoni SF. Effects of radiation on tumor intravascular oxygenation, vascular configuration, development of hypoxia, and clonogenic survival. Radiation Research. 155: 360-8. PMID 11175672 DOI: 10.1667/0033-7587(2001)155[0360:Eoroti]2.0.Co;2 |
0.404 |
|
| 2000 |
Egan RM, Yorkey C, Black R, Loh WK, Stevens JL, Storozynsky E, Lord EM, Frelinger JG, Woodward JG. In vivo behavior of peptide-specific T cells during mucosal tolerance induction: antigen introduced through the mucosa of the conjunctiva elicits prolonged antigen-specific T cell priming followed by anergy. Journal of Immunology (Baltimore, Md. : 1950). 164: 4543-50. PMID 10779755 DOI: 10.4049/Jimmunol.164.9.4543 |
0.378 |
|
| 2000 |
Lee J, Moran JP, Fenton BM, Koch CJ, Frelinger JG, Keng PC, Lord EM. Alteration of tumour response to radiation by interleukin-2 gene transfer British Journal of Cancer. 82: 937-944. PMID 10732769 DOI: 10.1054/Bjoc.1999.1022 |
0.331 |
|
| 2000 |
Fenton BM, Lord EM, Paoni SF. Enhancement of tumor perfusion and oxygenation by carbogen and nicotinamide during single- and multifraction irradiation. Radiation Research. 153: 75-83. PMID 10630980 DOI: 10.1667/0033-7587(2000)153[0075:Eotpao]2.0.Co;2 |
0.354 |
|
| 1999 |
Storozynsky E, Woodward JG, Frelinger JG, Lord EM. Interleukin-3 and granulocyte-macrophage colony-stimulating factor enhance the generation and function of dendritic cells Immunology. 97: 138-149. PMID 10447725 DOI: 10.1046/J.1365-2567.1999.00741.X |
0.372 |
|
| 1999 |
Clyman RI, Chan CY, Mauray F, Chen YQ, Cox W, Seidner SR, Lord EM, Weiss H, Waleh N, Evans SM, Koch CJ. Permanent anatomic closure of the ductus arteriosus in newborn baboons: The roles of postnatal constriction, hypoxia, and gestation Pediatric Research. 45: 19-29. PMID 9890604 DOI: 10.1203/00006450-199901000-00005 |
0.326 |
|
| 1999 |
Hahn SM, Koch CJ, Hsi RA, Stevens CW, Fraker DL, Chalian AA, Rubin SC, Lord EM, McKenna WG, Evans SM. 2019 Preliminary results of a phase I trial of the 2-nitroimidazole, EF5, an agent for the detection of tumor hypxia International Journal of Radiation Oncology Biology Physics. 45: 288. DOI: 10.1016/S0360-3016(99)90289-4 |
0.313 |
|
| 1998 |
Fenton BM, Paoni SF, Koch CJ, Lord EM. Effect of local irradiation on tumor oxygenation, perfused vessel density, and development of hypoxia Advances in Experimental Medicine and Biology. 454: 619-628. PMID 9889942 DOI: 10.1007/978-1-4615-4863-8_73 |
0.416 |
|
| 1998 |
Wei C, Callahan BP, Turner MJ, Willis RA, Lord EM, Barth RK, Frelinger JG. Regulation of human prostate-specific antigen gene expression in transgenic mice: evidence for an enhancer between the PSA and human glandular kallikrein-1 genes. International Journal of Molecular Medicine. 2: 487-96. PMID 9857240 DOI: 10.3892/Ijmm.2.4.487 |
0.301 |
|
| 1998 |
Willis RA, Wei C, Turner MJ, Callahan BP, Pugh AE, Barth RK, Lord EM, Frelinger JG. A transgenic strategy for analyzing the regulatory regions of the human prostate-specific antigen gene: potential applications for the treatment of prostate cancer (Review). International Journal of Molecular Medicine. 1: 379-86. PMID 9852240 DOI: 10.3892/Ijmm.1.2.379 |
0.333 |
|
| 1998 |
Lord EM, Yeh KY, Moran JA, Storozynsky E, Frelinger JG. IL-3-mediated enhancement of particulate antigen presentation by macrophages. Journal of Immunotherapy (Hagerstown, Md. : 1997). 21: 205-10. PMID 9610912 DOI: 10.1097/00002371-199805000-00006 |
0.468 |
|
| 1998 |
Lord EM, Frelinger JG. Tumor immunotherapy: Cytokines and antigen presentation Cancer Immunology Immunotherapy. 46: 75-81. PMID 9558002 DOI: 10.1007/S002620050464 |
0.499 |
|
| 1997 |
Yeh K, Chen Z, Nasir A, Ohsuga Y, Takashima A, Lord EM, Gaspari AA. Expression of B7-1 by Pam 212 squamous cell carcinoma enhances tumor cell interactions with dendritic epidermal T cells but does not affect in vivo tumor growth Journal of Investigative Dermatology. 109: 728-733. PMID 9406812 DOI: 10.1111/1523-1747.Ep12340723 |
0.504 |
|
| 1997 |
Nozue M, Lee I, Yuan F, Teicher BA, Brizel DM, Dewhirst MW, Milross CC, Milas L, Song CW, Thomas CD, Guichard M, Evans SM, Koch CJ, Lord EM, Jain RK, et al. Interlaboratory variation in oxygen tension measurement by Eppendorf 'Histograph' and comparison with hypoxic marker Journal of Surgical Oncology. 66: 30-38. PMID 9290690 DOI: 10.1002/(Sici)1096-9098(199709)66:1<30::Aid-Jso7>3.0.Co;2-O |
0.351 |
|
| 1997 |
Wei C, Willis RA, Tilton BR, Looney RJ, Lord EM, Barth RK, Frelinger JG. Tissue-specific expression of the human prostate-specific antigen gene in transgenic mice: implications for tolerance and immunotherapy. Proceedings of the National Academy of Sciences of the United States of America. 94: 6369-74. PMID 9177224 DOI: 10.1073/Pnas.94.12.6369 |
0.367 |
|
| 1996 |
Woods ML, Koch CJ, Lord EM. Detection of individual hypoxic cells in multicellular spheroids by flow cytometry using the 2-nitroimidazole, EF5, and monoclonal antibodies International Journal of Radiation Oncology Biology Physics. 34: 93-101. PMID 12118570 DOI: 10.1016/0360-3016(95)02006-3 |
0.385 |
|
| 1996 |
Wei C, Storozynsky E, McAdam AJ, Yeh KY, Tilton BR, Willis RA, Barth RK, Looney RJ, Lord EM, Frelinger JG. Expression of human prostate-specific antigen (PSA) in a mouse tumor cell line reduces tumorigenicity and elicits PSA-specific cytotoxic T lymphocytes. Cancer Immunology, Immunotherapy : Cii. 42: 362-8. PMID 8830740 DOI: 10.1007/S002620050295 |
0.488 |
|
| 1996 |
Lee J, Siemann DW, Koch CJ, Lord EM. Direct relationship between radiobiological hypoxia in tumors and monoclonal antibody detection of EF5 cellular adducts International Journal of Cancer. 67: 372-378. PMID 8707411 DOI: 10.1002/(Sici)1097-0215(19960729)67:3<372::Aid-Ijc11>3.0.Co;2-A |
0.485 |
|
| 1996 |
Pulaski BA, Yeh KY, Shastri N, Maltby KM, Penney DP, Lord EM, Frelinger JG. Interleukin 3 enhances cytotoxic T lymphocyte development and class I major histocompatibility complex "re-presentation" of exogenous antigen by tumor-infiltrating antigen-presenting cells Proceedings of the National Academy of Sciences of the United States of America. 93: 3669-3674. PMID 8622994 DOI: 10.1073/Pnas.93.8.3669 |
0.493 |
|
| 1995 |
McAdam AJ, Pulaski BA, Harkins SS, Hutter EK, Lord EM, Frelinger JG. Synergistic effects of co-expression of the TH1 cytokines IL-2 and IFN-gamma on generation of murine tumor-reactive cytotoxic cells. International Journal of Cancer. 61: 628-34. PMID 7768635 DOI: 10.1002/Ijc.2910610508 |
0.424 |
|
| 1995 |
Yeh KY, Pulaski BA, Woods ML, McAdam AJ, Gaspari AA, Frelinger JG, Lord EM. B7-1 enhances natural killer cell-mediated cytotoxicity and inhibits tumor growth of a poorly immunogenic murine carcinoma. Cellular Immunology. 165: 217-24. PMID 7553886 DOI: 10.1006/Cimm.1995.1208 |
0.444 |
|
| 1995 |
McAdam AJ, Pulaski BA, Storozynsky E, Yeh KY, Sickel JZ, Frelinger JG, Lord EM. Analysis of the effect of cytokines (interleukins 2, 3, 4, and 6, granulocyte-monocyte colony-stimulating factor, and interferon-gamma) on generation of primary cytotoxic T lymphocytes against a weakly immunogenic tumor. Cellular Immunology. 165: 183-92. PMID 7553882 DOI: 10.1006/Cimm.1995.1204 |
0.387 |
|
| 1995 |
Evans SM, Joiner B, Jenkins WT, Laughlin KM, Lord EM, Koch CJ. Identification of hypoxia in cells and tissues of epigastric 9L rat glioma using EF5 [2-(2-nitro-1H-imidazol-1-yl)-N-(2, 2, 3, 3, 3-pentafluoropropyl) acetamide] British Journal of Cancer. 72: 875-882. PMID 7547234 DOI: 10.1038/Bjc.1995.427 |
0.303 |
|
| 1995 |
Koch CJ, Evans SM, Lord EM. Oxygen dependence of cellular uptake of EF5 [2-(2-nitro-1H-imidazol-1-yl)-N-(2, 2, 3, 3, 3-pentafluoropropyl)a cet amide]: Analysis of drug adducts by fluorescent antibodies vs bound radioactivity British Journal of Cancer. 72: 869-874. PMID 7547233 DOI: 10.1038/Bjc.1995.426 |
0.304 |
|
| 1993 |
McAdam A, Pulaski B, Harkins S, Hutter E, Frelinger J, Lord E. Coexpression of IL-2 and γ-IFN enhances tumor immunity Annals of the New York Academy of Sciences. 690: 349-351. PMID 8368753 DOI: 10.1111/J.1749-6632.1993.Tb44027.X |
0.407 |
|
| 1993 |
Lord E, McAdam A, Felcher A, Woods M, Pulaski B, Hutter E, Frelinger J. Transfection of TGF-β producing tumors with IL-2 elicits tumor rejection Annals of the New York Academy of Sciences. 690: 346-348. PMID 8368752 DOI: 10.1111/J.1749-6632.1993.Tb44026.X |
0.375 |
|
| 1993 |
McAdam AJ, Yeh KY, Pulaski BA, Frelinger JG, Lord EM. Interleukin-3 inhibits the generation of nonspecific killers by interleukin-2 Journal of Immunotherapy. 14: 293-297. PMID 8280711 DOI: 10.1097/00002371-199311000-00007 |
0.355 |
|
| 1992 |
McAdam AJ, Blieden TM, Frelinger JG, Lord EM. CD4-class II major histocompatibility complex interaction does not enhance killing by a class I-restricted CD4+CD8+ cytotoxic T cell clone European Journal of Immunology. 22: 2461-2464. PMID 1516633 DOI: 10.1002/Eji.1830220942 |
0.319 |
|
| 1991 |
Blieden TM, McAdam AJ, Foresman MD, Cerosaletti KM, Frelinger JG, Lord EM. Class-I MHC expression in the mouse lung carcinoma, line 1: a model for class-I inducible tumors. International Journal of Cancer. Supplement = Journal International Du Cancer. Supplement. 6: 82-9. PMID 1906056 DOI: 10.1002/Ijc.2910470717 |
0.464 |
|
| 1990 |
Loeffler DA, Keng PC, Baggs RB, Lord EM. Lymphocytic infiltration and cytotoxicity under hypoxic conditions in the EMT6 mouse mammary tumor. International Journal of Cancer. 45: 462-467. PMID 2307536 DOI: 10.1002/Ijc.2910450315 |
0.468 |
|
| 1990 |
Cerosaletti KM, Blieden TM, Harwell LW, Welsh KM, Frelinger JG, Lord EM. Alteration of the metastatic potential of line 1 lung carcinoma cells: opposite effects of class I antigen induction by interferons versus DMSO or gene transfection. Cellular Immunology. 127: 299-310. PMID 1691690 DOI: 10.1016/0008-8749(90)90134-D |
0.427 |
|
| 1989 |
Wilson KM, Siegal G, Lord EM. Tumor necrosis factor-mediated cytotoxicity by tumor-associated macrophages. Cellular Immunology. 123: 158-165. PMID 2776218 DOI: 10.1016/0008-8749(89)90276-1 |
0.428 |
|
| 1987 |
Bahler DW, Frelinger JG, Harwell LW, Lord EM. Reduced tumorigenicity of a spontaneous mouse lung carcinoma following H-2 gene transfection Proceedings of the National Academy of Sciences of the United States of America. 84: 4562-4566. PMID 3496596 DOI: 10.1073/Pnas.84.13.4562 |
0.472 |
|
| 1987 |
Loeffler D, Keng P, Wilson K, Lord E. Comparison of fluorescence intensity of Hoechst 33342-stained EMT6 tumour cells and tumour-infiltrating host cells. British Journal of Cancer. 56: 571-576. PMID 2447928 DOI: 10.1038/Bjc.1987.243 |
0.35 |
|
| 1986 |
Wilson KM, Lord EM. Effects of radiation on host-tumor interactions using the multicellular tumor spheroid model. Cancer Immunology, Immunotherapy. 23: 20-24. PMID 2876773 DOI: 10.1007/Bf00205550 |
0.494 |
|
| 1984 |
Lord EM, Burkhardt G. Assessment of in situ host immunity to syngeneic tumors utilizing the multicellular spheroid model. Cellular Immunology. 85: 340-50. PMID 6713544 DOI: 10.1016/0008-8749(84)90248-X |
0.502 |
|
| 1984 |
Harwell LW, Bolognino M, Bidlack JM, Knapp RJ, Lord EM. A freezing method for cell fusions to distribute and reduce labor and permit more thorough early evaluation of hybridomas. Journal of Immunological Methods. 66: 59-67. PMID 6363553 DOI: 10.1016/0022-1759(84)90247-3 |
0.301 |
|
| 1984 |
Lord EM, Keng PC. Methods for using centrifugal elutriation to separate malignant and lymphoid cell populations. Journal of Immunological Methods. 68: 147-155. PMID 6323581 DOI: 10.1016/0022-1759(84)90145-5 |
0.46 |
|
| 1981 |
Siemann DW, Lord EM, Keng PC, Wheeler KT. Cell subpopulations dispersed from solid tumours and separated by centrifugal elutriation. British Journal of Cancer. 44: 100-8. PMID 7259956 DOI: 10.1038/Bjc.1981.154 |
0.358 |
|
| 1981 |
Keng PC, Wheeler KT, Siemann DW, Lord EM. Direct synchronization of cells from solid tumors by centrifugal elutriation. Experimental Cell Research. 134: 15-22. PMID 7250214 DOI: 10.1016/0014-4827(81)90458-4 |
0.449 |
|
| 1981 |
Greenstein JL, Lord E, Kappler JW, Marrack PC. Analysis of the response of B cells from CBA/N-defective mice to nonspecific T cell help. The Journal of Experimental Medicine. 154: 1608-17. PMID 6975350 DOI: 10.1084/Jem.154.5.1608 |
0.363 |
|
| 1980 |
Lord EM, Nardella GB, Sutherland RM. The multicellular tumor spheroid model: I. Characterization of the allograft response in sensitized mice Cellular Immunology. 52: 119-131. PMID 7388952 DOI: 10.1016/0008-8749(80)90405-0 |
0.504 |
|
| 1980 |
Lord EM, Nardella G. The multicellular tumor spheroid model. II. Characterization of the primary allograft response in unsensitized mice. Transplantation. 29: 119-124. DOI: 10.1097/00007890-198002000-00006 |
0.412 |
|
| 1979 |
Lord EM, Penney DP, Sutherland RM, Cooper RA. Morphological and functional characteristics of cells infiltrating and destroying tumor multicellular spheroids in vivo. Virchows Archiv. B, Cell Pathology Including Molecular Pathology. 31: 103-16. PMID 42207 DOI: 10.1007/Bf02889928 |
0.489 |
|
| 1978 |
Sutherland R, Lord E, Landry J, Baird M, Siemann D. Immunological responses to two different models of micrometastases of a mouse tumor International Journal of Radiation Oncology*Biology*Physics. 4: 90-91. DOI: 10.1016/0360-3016(78)90252-3 |
0.409 |
|
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