Robert Koffie, MD, PhD - Publications

Affiliations: 
Harvard Medical School, Boston, MA, United States 

11 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Pickett EK, Koffie RM, Wegmann S, Henstridge CM, Herrmann AG, Colom-Cadena M, Lleo A, Kay KR, Vaught M, Soberman R, Walsh DM, Hyman BT, Spires-Jones TL. Non-Fibrillar Oligomeric Amyloid-β within Synapses. Journal of Alzheimer's Disease : Jad. PMID 27258414 DOI: 10.3233/Jad-160007  0.734
2013 Hudry E, Dashkoff J, Roe AD, Takeda S, Koffie RM, Hashimoto T, Scheel M, Spires-Jones T, Arbel-Ornath M, Betensky R, Davidson BL, Hyman BT. Gene transfer of human Apoe isoforms results in differential modulation of amyloid deposition and neurotoxicity in mouse brain. Science Translational Medicine. 5: 212ra161. PMID 24259049 DOI: 10.1126/Scitranslmed.3007000  0.684
2013 Kay KR, Smith C, Wright AK, Serrano-Pozo A, Pooler AM, Koffie R, Bastin ME, Bak TH, Abrahams S, Kopeikina KJ, McGuone D, Frosch MP, Gillingwater TH, Hyman BT, Spires-Jones TL. Studying synapses in human brain with array tomography and electron microscopy. Nature Protocols. 8: 1366-80. PMID 23787894 DOI: 10.1038/Nprot.2013.078  0.723
2012 Koffie RM, Hashimoto T, Tai HC, Kay KR, Serrano-Pozo A, Joyner D, Hou S, Kopeikina KJ, Frosch MP, Lee VM, Holtzman DM, Hyman BT, Spires-Jones TL. Apolipoprotein E4 effects in Alzheimer's disease are mediated by synaptotoxic oligomeric amyloid-β. Brain : a Journal of Neurology. 135: 2155-68. PMID 22637583 DOI: 10.1093/Brain/Aws127  0.757
2011 Koffie RM, Farrar CT, Saidi LJ, William CM, Hyman BT, Spires-Jones TL. Nanoparticles enhance brain delivery of blood-brain barrier-impermeable probes for in vivo optical and magnetic resonance imaging. Proceedings of the National Academy of Sciences of the United States of America. 108: 18837-42. PMID 22065785 DOI: 10.1073/Pnas.1111405108  0.621
2011 Koffie RM, Hyman BT, Spires-Jones TL. Alzheimer's disease: synapses gone cold. Molecular Neurodegeneration. 6: 63. PMID 21871088 DOI: 10.1186/1750-1326-6-63  0.722
2011 Kopeikina KJ, Carlson GA, Pitstick R, Ludvigson AE, Peters A, Luebke JI, Koffie RM, Frosch MP, Hyman BT, Spires-Jones TL. Tau accumulation causes mitochondrial distribution deficits in neurons in a mouse model of tauopathy and in human Alzheimer's disease brain. The American Journal of Pathology. 179: 2071-82. PMID 21854751 DOI: 10.1016/J.Ajpath.2011.07.004  0.747
2011 Spires-Jones TL, Kopeikina KJ, Koffie RM, de Calignon A, Hyman BT. Are tangles as toxic as they look? Journal of Molecular Neuroscience : Mn. 45: 438-44. PMID 21638071 DOI: 10.1007/S12031-011-9566-7  0.762
2011 Holtzman D, Hyman B, Lee V, Spires-Jones T, Koffie R, Hashimoto T, Joyner D, Hou S, Kopeikina K, Frosch M. O1-05-01: APOE4 plays a role in Abeta-mediated synapse loss in Alzheimer's disease Alzheimer's & Dementia. 7: S103-S104. DOI: 10.1016/J.Jalz.2011.05.256  0.686
2011 Spires-Jones TL, Kopeikina KJ, Koffie RM, de Calignon A, Hyman BT. Erratum to: Are Tangles as Toxic as They Look? Journal of Molecular Neuroscience. 45: 742-742. DOI: 10.1007/S12031-011-9581-8  0.708
2009 Koffie RM, Meyer-Luehmann M, Hashimoto T, Adams KW, Mielke ML, Garcia-Alloza M, Micheva KD, Smith SJ, Kim ML, Lee VM, Hyman BT, Spires-Jones TL. Oligomeric amyloid beta associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques. Proceedings of the National Academy of Sciences of the United States of America. 106: 4012-7. PMID 19228947 DOI: 10.1073/Pnas.0811698106  0.706
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