Irene F. Newsham - Publications

Affiliations: 
Virginia Commonwealth University, Richmond, VA, United States 
Area:
Molecular Biology, Cell Biology, Oncology

38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Salameh A, Lee AK, Cardó-Vila M, Nunes DN, Efstathiou E, Staquicini FI, Dobroff AS, Marchiò S, Navone NM, Hosoya H, Lauer RC, Wen S, Salmeron CC, Hoang A, Newsham I, et al. PRUNE2 is a human prostate cancer suppressor regulated by the intronic long noncoding RNA PCA3. Proceedings of the National Academy of Sciences of the United States of America. PMID 26080435 DOI: 10.1073/Pnas.1507882112  0.307
2014 Chipman AD, Ferrier DE, Brena C, Qu J, Hughes DS, Schröder R, Torres-Oliva M, Znassi N, Jiang H, Almeida FC, Alonso CR, Apostolou Z, Aqrawi P, Arthur W, Barna JC, ... ... Newsham I, et al. The first myriapod genome sequence reveals conservative arthropod gene content and genome organisation in the centipede Strigamia maritima. Plos Biology. 12: e1002005. PMID 25423365 DOI: 10.1371/Journal.Pbio.1002005  0.312
2013 Liu L, Sabo A, Neale BM, Nagaswamy U, Stevens C, Lim E, Bodea CA, Muzny D, Reid JG, Banks E, Coon H, Depristo M, Dinh H, Fennel T, Flannick J, ... ... Newsham I, et al. Analysis of rare, exonic variation amongst subjects with autism spectrum disorders and population controls. Plos Genetics. 9: e1003443. PMID 23593035 DOI: 10.1371/Journal.Pgen.1003443  0.301
2013 Lim ET, Raychaudhuri S, Sanders SJ, Stevens C, Sabo A, MacArthur DG, Neale BM, Kirby A, Ruderfer DM, Fromer M, Lek M, Liu L, Flannick J, Ripke S, Nagaswamy U, ... ... Newsham I, et al. Rare complete knockouts in humans: population distribution and significant role in autism spectrum disorders. Neuron. 77: 235-42. PMID 23352160 DOI: 10.1016/J.Neuron.2012.12.029  0.338
2012 Muzny DM, Bainbridge MN, Chang K, Dinh HH, Drummond JA, Fowler G, Kovar CL, Lewis LR, Morgan MB, Newsham IF, Reid JG, Santibanez J, Shinbrot E, Trevino LR, Wu YQ, et al. Comprehensive molecular characterization of human colon and rectal cancer Nature. 487: 330-337. PMID 22810696 DOI: 10.1038/Nature11252  0.381
2012 Neale BM, Kou Y, Liu L, Ma'ayan A, Samocha KE, Sabo A, Lin CF, Stevens C, Wang LS, Makarov V, Polak P, Yoon S, Maguire J, Crawford EL, Campbell NG, ... ... Newsham I, et al. Patterns and rates of exonic de novo mutations in autism spectrum disorders. Nature. 485: 242-5. PMID 22495311 DOI: 10.1038/Nature11011  0.342
2012 Mackay TF, Richards S, Stone EA, Barbadilla A, Ayroles JF, Zhu D, Casillas S, Han Y, Magwire MM, Cridland JM, Richardson MF, Anholt RR, Barrón M, Bess C, Blankenburg KP, ... ... Newsham I, et al. The Drosophila melanogaster Genetic Reference Panel. Nature. 482: 173-8. PMID 22318601 DOI: 10.1038/Nature10811  0.317
2012 Stark MS, Woods SL, Gartside MG, Bonazzi VF, Dutton-Regester K, Aoude LG, Chow D, Sereduk C, Niemi NM, Tang N, Ellis JJ, Reid J, Zismann V, Tyagi S, Muzny D, ... Newsham I, et al. Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing. Nature Genetics. 44: 165-9. PMID 22197930 DOI: 10.1038/Ng.1041  0.303
2011 Murdock DR, Clark GD, Bainbridge MN, Newsham I, Wu YQ, Muzny DM, Cheung SW, Gibbs RA, Ramocki MB. Whole-exome sequencing identifies compound heterozygous mutations in WDR62 in siblings with recurrent polymicrogyria. American Journal of Medical Genetics. Part A. 155: 2071-7. PMID 21834044 DOI: 10.1002/Ajmg.A.34165  0.331
2010 Coventry A, Bull-Otterson LM, Liu X, Clark AG, Maxwell TJ, Crosby J, Hixson JE, Rea TJ, Muzny DM, Lewis LR, Wheeler DA, Sabo A, Lusk C, Weiss KG, Akbar H, ... ... Newsham I, et al. Deep resequencing reveals excess rare recent variants consistent with explosive population growth. Nature Communications. 1: 131. PMID 21119644 DOI: 10.1038/Ncomms1130  0.311
2009 Di X, Shiu RP, Newsham IF, Gewirtz DA. Apoptosis, autophagy, accelerated senescence and reactive oxygen in the response of human breast tumor cells to adriamycin. Biochemical Pharmacology. 77: 1139-50. PMID 19185564 DOI: 10.1016/J.Bcp.2008.12.016  0.313
2007 Heller G, Geradts J, Ziegler B, Newsham I, Filipits M, Markis-Ritzinger EM, Kandioler D, Berger W, Stiglbauer W, Depisch D, Pirker R, Zielinski CC, Zöchbauer-Müller S. Downregulation of TSLC1 and DAL-1 expression occurs frequently in breast cancer. Breast Cancer Research and Treatment. 103: 283-91. PMID 17260099 DOI: 10.1007/S10549-006-9377-7  0.435
2006 Jiang W, Newsham IF. The tumor suppressor DAL-1/4.1B and protein methylation cooperate in inducing apoptosis in MCF-7 breast cancer cells. Molecular Cancer. 5: 4. PMID 16420693 DOI: 10.1186/1476-4598-5-4  0.489
2005 Kuns R, Kissil JL, Newsham IF, Jacks T, Gutmann DH, Sherman LS. Protein 4.1B expression is induced in mammary epithelial cells during pregnancy and regulates their proliferation. Oncogene. 24: 6502-15. PMID 16007173 DOI: 10.1038/Sj.Onc.1208813  0.409
2005 Jiang W, Roemer ME, Newsham IF. The tumor suppressor DAL-1/4.1B modulates protein arginine N-methyltransferase 5 activity in a substrate-specific manner. Biochemical and Biophysical Research Communications. 329: 522-30. PMID 15737618 DOI: 10.1016/J.Bbrc.2005.01.153  0.436
2004 Ohno N, Terada N, Murata S, Yamakawa H, Newsham IF, Katoh R, Ohara O, Ohno S. Immunolocalization of protein 4.1B/DAL-1 during neoplastic transformation of mouse and human intestinal epithelium. Histochemistry and Cell Biology. 122: 579-86. PMID 15517334 DOI: 10.1007/s00418-004-0716-7  0.303
2004 Singh V, Miranda TB, Jiang W, Frankel A, Roemer ME, Robb VA, Gutmann DH, Herschman HR, Clarke S, Newsham IF. DAL-1/4.1B tumor suppressor interacts with protein arginine N-methyltransferase 3 (PRMT3) and inhibits its ability to methylate substrates in vitro and in vivo. Oncogene. 23: 7761-71. PMID 15334060 DOI: 10.1038/Sj.Onc.1208057  0.451
2004 Kittiniyom K, Mastronardi M, Roemer M, Wells WA, Greenberg ER, Titus-Ernstoff L, Newsham IF. Allele-specific loss of heterozygosity at the DAL-1/4.1B (EPB41L3) tumor-suppressor gene locus in the absence of mutation. Genes, Chromosomes & Cancer. 40: 190-203. PMID 15138999 DOI: 10.1002/Gcc.20034  0.742
2003 Fouladi M, Helton K, Dalton J, Gilger E, Gajjar A, Merchant T, Kun L, Newsham I, Burger P, Fuller C. Clear cell ependymoma: a clinicopathologic and radiographic analysis of 10 patients. Cancer. 98: 2232-2244. PMID 14601094 DOI: 10.1002/Cncr.11783  0.306
2003 Mihaila D, Gutiérrez JA, Rosenblum ML, Newsham IF, Bögler O, Rempel SA. Meningiomas: analysis of loss of heterozygosity on chromosome 10 in tumor progression and the delineation of four regions of chromosomal deletion in common with other cancers. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 4435-42. PMID 14555516  0.367
2002 Charboneau AL, Singh V, Yu T, Newsham IF. Suppression of growth and increased cellular attachment after expression of DAL-1 in MCF-7 breast cancer cells. International Journal of Cancer. Journal International Du Cancer. 100: 181-8. PMID 12115567 DOI: 10.1002/Ijc.10470  0.709
2002 Singh PK, Gutmann DH, Fuller CE, Newsham IF, Perry A. Differential involvement of protein 4.1 family members DAL-1 and NF2 in intracranial and intraspinal ependymomas. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 15: 526-31. PMID 12011257 DOI: 10.1038/Modpathol.3880558  0.446
2002 Yu T, Robb VA, Singh V, Gutmann DH, Newsham IF. The 4.1/ezrin/radixin/moesin domain of the DAL-1/Protein 4.1B tumour suppressor interacts with 14-3-3 proteins. The Biochemical Journal. 365: 783-9. PMID 11996670 DOI: 10.1042/Bj20020060  0.369
2002 Bogler O, Finniss S, Kittiniyom K, Rempel S, Rosenblum M, Mikkelsen T, Newsham I. Studying the heterogeneity of brain tumors using medium throughput LOH analysis. Cytometry. 47: 52-5. PMID 11774351 DOI: 10.1002/Cyto.10035  0.727
2001 Perry A, Giannini C, Raghavan R, Scheithauer BW, Banerjee R, Margraf L, Bowers DC, Lytle RA, Newsham IF, Gutmann DH. Aggressive phenotypic and genotypic features in pediatric and NF2-associated meningiomas: a clinicopathologic study of 53 cases. Journal of Neuropathology and Experimental Neurology. 60: 994-1003. PMID 11589430 DOI: 10.1093/Jnen/60.10.994  0.378
2001 Kittiniyom K, Gorse KM, Dalbegue F, Lichy JH, Taubenberger JK, Newsham IF. Allelic loss on chromosome band 18p11.3 occurs early and reveals heterogeneity in breast cancer progression Breast Cancer Research. 3: 192-198. PMID 11305954 DOI: 10.1186/Bcr294  0.724
2000 Newsham IF, Gorse KM, Rempel SA, Luckey J, Golden JB, Bögler O. Use of horizontal ultrathin gel electrophoresis to analyze allelic deletions in chromosome band 11p15.5 in gliomas Neuro-Oncology. 2: 1-5. PMID 11302248 DOI: 10.1093/Neuonc/2.1.1  0.495
2000 Perry A, Cai DX, Scheithauer BW, Swanson PE, Lohse CM, Newsham IF, Weaver A, Gutmann DH. Merlin, DAL-1, and progesterone receptor expression in clinicopathologic subsets of meningioma: a correlative immunohistochemical study of 175 cases. Journal of Neuropathology and Experimental Neurology. 59: 872-9. PMID 11079777 DOI: 10.1093/Jnen/59.10.872  0.521
2000 Gutmann DH, Donahoe J, Perry A, Lemke N, Gorse K, Kittiniyom K, Rempel SA, Gutierrez JA, Newsham IF. Loss of DAL-1, a protein 4.1-related tumor suppressor, is an important early event in the pathogenesis of meningiomas. Human Molecular Genetics. 9: 1495-500. PMID 10888600 DOI: 10.1093/Hmg/9.10.1495  0.754
1999 Tran Y, Benbatoul K, Gorse K, Rempel S, Futreal A, Green M, Newsham I. Novel regions of allelic deletion on chromosome 18p in tumors of the lung, brain and breast. Oncogene. 17: 3499-505. PMID 10030674 DOI: 10.1038/Sj.Onc.1202258  0.569
1996 Besnard-Guérin C, Winqvist R, Newsham I, Cavenee WK. Population variation at the polymorphic ApaLI restriction enzyme site in intron 5 of the WT1 gene Clinical Genetics. 50: 555-557. PMID 9147899 DOI: 10.1111/J.1399-0004.1996.Tb02738.X  0.346
1996 Issa JP, Vertino PM, Boehm CD, Newsham IF, Baylin SB. Switch from monoallelic to biallelic human IGF2 promoter methylation during aging and carcinogenesis. Proceedings of the National Academy of Sciences of the United States of America. 93: 11757-62. PMID 8876210 DOI: 10.1073/Pnas.93.21.11757  0.35
1996 Wasserman LM, Newsham I, Huang HJS, Cavenee WK. cAMP effects on myogenic gene expression in rhabdomyosarcoma cells Experimental Cell Research. 227: 55-62. PMID 8806451 DOI: 10.1006/Excr.1996.0249  0.422
1995 Besnard-Guerin C, Cavenee W, Newsham I. The t(11;22)(p15.5;q11.23) in a retroperitoneal rhabdoid tumor also includes a regional deletion distal to CRYBB2 on 22q Genes Chromosomes and Cancer. 13: 145-150. PMID 7669732 DOI: 10.1002/Gcc.2870130302  0.488
1995 Newsham I, Kindler-Rohrborn A, Daub D, Cavenee W. A constitutional BWS-related t(11;16) chromosome translocation occurring in the same region of chromosome 16 implicated in Wilms' tumors Genes Chromosomes and Cancer. 12: 1-7. PMID 7534105 DOI: 10.1002/Gcc.2870120102  0.473
1994 Newsham I, Daub D, Besnard-Guerin C, Cavenee W. Molecular sublocalization and characterization of the 11;22 translocation breakpoint in a malignant rhabdoid tumor. Genomics. 19: 433-40. PMID 8188285 DOI: 10.1006/Geno.1994.1091  0.523
1994 Besnard-Guérin C, Cavenee WK, Newsham I. A new highly polymorphic DNA restriction site marker in the 5' region of the human tyrosine hydroxylase gene (TH) detecting loss of heterozygosity in human embryonal rhabdomyosarcoma. Human Genetics. 93: 349-50. PMID 7510263 DOI: 10.1007/Bf00212038  0.444
1993 Newsham I, Cavenee W. Tumors and developmental anomalies associated with Wilms tumor. Medical and Pediatric Oncology. 21: 199-204. PMID 8383280 DOI: 10.1002/Mpo.2950210309  0.448
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