Perry B. Hackett - Publications

Affiliations: 
University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Molecular Biology, Cell Biology

130 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Crane AT, Aravalli RN, Asakura A, Grande AW, Krishna VD, Carlson DF, Cheeran MC, Danczyk G, Dutton JR, Hackett PB, Hu WS, Li L, Lu WC, Miller ZD, O'Brien TD, et al. Interspecies Organogenesis for Human Transplantation. Cell Transplantation. 963689719845351. PMID 31426664 DOI: 10.1177/0963689719845351  0.367
2017 Aronovich EL, Hyland KA, Hall BC, Bell JB, Olson ER, Rusten MU, Hunter DW, Ellinwood NM, McIvor RS, Hackett PB. Prolonged expression of secreted enzymes in dogs after liver-directed delivery of Sleeping Beauty transposons: implications for non-viral gene therapy of systemic disease. Human Gene Therapy. PMID 28530135 DOI: 10.1089/Hum.2017.004  0.416
2017 Hyland KA, Aronovich EL, Olson ER, Bell JB, Rusten MU, Gunther R, Hunter DW, Hackett PB, McIvor RS. Transgene Expression in Dogs after Liver-Directed Hydrodynamic Delivery of Sleeping Beauty Transposons Using Balloon Catheters. Human Gene Therapy. PMID 28447859 DOI: 10.1089/Hum.2017.003  0.438
2017 Abdelrahman H, ElHady M, Alcivar-Warren A, Allen S, Al-Tobasei R, Bao L, Beck B, Blackburn H, Bosworth B, Buchanan J, Chappell J, Daniels W, Dong S, Dunham R, ... ... Hackett P, et al. Aquaculture genomics, genetics and breeding in the United States: current status, challenges, and priorities for future research. Bmc Genomics. 18: 191. PMID 28219347 DOI: 10.1186/S12864-017-3557-1  0.334
2017 Fong Y, Hackett PB. Acceptance and Access to Gene Editing: Science and Our Obligations to Mankind. Molecular Therapy : the Journal of the American Society of Gene Therapy. 25: 1-2. PMID 28129104 DOI: 10.1016/J.Ymthe.2016.12.012  0.416
2016 Kebriaei P, Singh H, Huls MH, Figliola MJ, Bassett R, Olivares S, Jena B, Dawson MJ, Kumaresan PR, Su S, Maiti S, Dai J, Moriarity B, Forget MA, Senyukov V, ... ... Hackett PB, et al. Phase I trials using Sleeping Beauty to generate CD19-specific CAR T cells. The Journal of Clinical Investigation. PMID 27482888 DOI: 10.1172/Jci86721  0.346
2016 Watson AL, Carlson DF, Largaespada DA, Hackett PB, Fahrenkrug SC. Engineered Swine Models of Cancer. Frontiers in Genetics. 7: 78. PMID 27242889 DOI: 10.3389/Fgene.2016.00078  0.596
2016 Dhande YK, Wagh BS, Hall BC, Sprouse D, Hackett PB, Reineke TM. N-Acetylgalactosamine Block-co-Polycations Form Stable Polyplexes with Plasmids and Promote Liver-Targeted Delivery. Biomacromolecules. PMID 26854615 DOI: 10.1021/Acs.Biomac.5B01555  0.334
2016 Tolstyka ZP, Phillips H, Cortez M, Wu Y, Ingle N, Bell JB, Hackett PB, Reineke TM. Trehalose-Based Block Copolycations Promote Polyplex Stabilization for Lyophilization and in Vivo pDNA Delivery. Acs Biomaterials Science & Engineering. 2: 43-55. PMID 26807438 DOI: 10.1021/Acsbiomaterials.5B00312  0.393
2016 Aronovich EL, Hyland KA, Hall BC, Bell JB, Olson ER, Rusten M, Hunter DW, Whitley CB, Ellinwood NM, McIvor RS, Hackett PB. 439. Prolonged Expression of Secreted Enzymes in Dogs After Liver Delivery of Sleeping Beauty Transposons: Implications for Non-Viral Gene Therapy of Mucopolysaccharidoses Types I and VII Molecular Therapy. 24: S174. DOI: 10.1016/S1525-0016(16)33248-8  0.389
2015 Wolf DA, Banerjee S, Hackett PB, Whitley CB, McIvor RS, Low WC. Gene therapy for neurologic manifestations of mucopolysaccharidoses. Expert Opinion On Drug Delivery. 12: 283-96. PMID 25510418 DOI: 10.1517/17425247.2015.966682  0.318
2015 Aronovich EL, Hackett PB. Lysosomal storage disease: gene therapy on both sides of the blood-brain barrier. Molecular Genetics and Metabolism. 114: 83-93. PMID 25410058 DOI: 10.1016/J.Ymgme.2014.09.011  0.349
2015 Herbig EJ, Hyland K, Xu M, de Laat R, Olson E, Aronovich E, Scholz M, Hackett P, Scott McIvor R. 373. Expression of Human Iduronidase from Sleeping Beauty Engineered Human B Lymphocytes as a Cellular Therapy for Mucopolysaccharidosis Type I Molecular Therapy. 23: S148. DOI: 10.1016/S1525-0016(16)33982-X  0.4
2015 Hall BC, Bell JB, Aronovich EL, Gunderman A, Farahani S, Fortin C, Hackett PB. 161. Directing Integration of SB Transposons Into Selected Genomic Sites in Liver for Non-Viral Gene Therapy Molecular Therapy. 23: S65. DOI: 10.1016/S1525-0016(16)33766-2  0.445
2015 Hackett PB, Aronovich EL, Bell JB, Rusten M, Hunter DW, Hall BC, Olson ER, Hyland KA, Matthew Ellinwood N, Scott McIvor R. 126. Non-Viral Gene Therapy By Liver-Directed Hydrodynamic Delivery of Sleeping Beauty Transposons to Treat Hemophilia and Mucopolysaccharidoses in Dogs Molecular Therapy. 23: S52. DOI: 10.1016/S1525-0016(16)33731-5  0.418
2015 Herbig EJ, Xu M, Hyland KA, Olson E, Aronovich E, Scholz M, Hackett PB, McIvor RS. Sleeping Beauty engineered human B lymphocytes express therapeutic levels of human iduronidase: A new approach for mucopolysaccharidosis type I Molecular Genetics and Metabolism. 114: S53-S54. DOI: 10.1016/J.Ymgme.2014.12.110  0.339
2015 Hall BC, Sanders MA, Barthel GM, Hackett PB. Microwave assisted CLARITY for whole organ surveillance Molecular Genetics and Metabolism. 114: S50. DOI: 10.1016/J.Ymgme.2014.12.100  0.378
2015 Hackett P. Non-viral gene therapy by liver-directed hydrodynamic delivery of Sleeping Beauty transposons to treat MPS in dogs Molecular Genetics and Metabolism. 114: S49-S50. DOI: 10.1016/J.Ymgme.2014.12.099  0.394
2014 Hackett PB, Aronovich EL. Rational design for enhanced gene therapy with DNA transposons. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 1575-7. PMID 25186559 DOI: 10.1038/Mt.2014.149  0.399
2014 Hackett PB, Somia NV. Delivering the second revolution in site-specific nucleases. Elife. 3: e02904. PMID 24843032 DOI: 10.7554/Elife.02904  0.355
2014 Carpentier CE, Schreifels JM, Aronovich EL, Carlson DF, Hackett PB, Nesmelova IV. NMR structural analysis of Sleeping Beauty transposase binding to DNA. Protein Science : a Publication of the Protein Society. 23: 23-33. PMID 24243759 DOI: 10.1002/Pro.2386  0.324
2014 Kebriaei P, Huls H, Singh H, Olivares S, Figliola M, Maiti S, Shihuang S, Kumar PR, Jena B, Forget MA, Ang S, Rineka J, Liu T, McNiece IK, Rondon G, ... Hackett P, et al. Adoptive Therapy Using Sleeping Beauty Gene Transfer System and Artificial Antigen Presenting Cells to Manufacture T Cells Expressing CD19-Specific Chimeric Antigen Receptor Blood. 124: 311-311. DOI: 10.1182/Blood.V124.21.311.311  0.317
2013 Carlson DF, Tan W, Hackett PB, Fahrenkrug SC. Editing livestock genomes with site-specific nucleases. Reproduction, Fertility, and Development. 26: 74-82. PMID 24305179 DOI: 10.1071/Rd13260  0.676
2013 Aronovich EL, Hall BC, Bell JB, McIvor RS, Hackett PB. Quantitative analysis of α-L-iduronidase expression in immunocompetent mice treated with the Sleeping Beauty transposon system. Plos One. 8: e78161. PMID 24205141 DOI: 10.1371/Journal.Pone.0078161  0.384
2013 Tan W, Carlson DF, Lancto CA, Garbe JR, Webster DA, Hackett PB, Fahrenkrug SC. Efficient nonmeiotic allele introgression in livestock using custom endonucleases. Proceedings of the National Academy of Sciences of the United States of America. 110: 16526-31. PMID 24014591 DOI: 10.1073/Pnas.1310478110  0.668
2013 Maiti SN, Huls H, Singh H, Dawson M, Figliola M, Olivares S, Rao P, Zhao YJ, Multani A, Yang G, Zhang L, Crossland D, Ang S, Torikai H, Rabinovich B, ... ... Hackett P, et al. Sleeping beauty system to redirect T-cell specificity for human applications. Journal of Immunotherapy (Hagerstown, Md. : 1997). 36: 112-23. PMID 23377665 DOI: 10.1097/Cji.0B013E3182811Ce9  0.342
2013 Hackett PB, Largaespada DA, Switzer KC, Cooper LJ. Evaluating risks of insertional mutagenesis by DNA transposons in gene therapy. Translational Research : the Journal of Laboratory and Clinical Medicine. 161: 265-83. PMID 23313630 DOI: 10.1016/J.Trsl.2012.12.005  0.445
2013 Kebriaei P, Huls H, Singh H, Olivares S, Figliola M, Kumar PR, Jena B, Jackson RN, Liu T, McNiece IK, Rondon G, Hackett P, Champlin RE, Shpall EJ, Cooper LJN. Adoptive Immunotherapy Following Umbilical Cord Blood Transplantation Using The Sleeping Beauty System and Artificial Antigen Presenting Cells To Generate Donor-Derived T Cells Expressing a CD19-Specific Chimeric Antigen Receptor Blood. 122: 4208-4208. DOI: 10.1182/Blood.V122.21.4208.4208  0.315
2013 Kebriaei P, Huls H, Singh H, Olivares S, Figliola M, Kumar PR, Jena B, Forget MA, Ang S, Jackson RN, Liu T, Bosque D, McNiece IK, Rondon G, Hackett P, et al. First Clinical Trials Employing Sleeping Beauty Gene Transfer System and Artificial Antigen Presenting Cells To Generate and Infuse T Cells Expressing CD19-Specific Chimeric Antigen Receptor Blood. 122: 166-166. DOI: 10.1182/Blood.V122.21.166.166  0.325
2013 Hall BC, Aronovich EL, Bell J, Hackett P. Mathematical modeling of transgenic IDUA expression mediated by the sleeping beauty transposon system in mice Molecular Genetics and Metabolism. 108: S46. DOI: 10.1016/J.Ymgme.2012.11.105  0.361
2012 Carlson DF, Fahrenkrug SC, Hackett PB. Targeting DNA With Fingers and TALENs. Molecular Therapy. Nucleic Acids. 1: e3. PMID 23344620 DOI: 10.1038/Mtna.2011.5  0.675
2012 Tan WS, Carlson DF, Walton MW, Fahrenkrug SC, Hackett PB. Precision editing of large animal genomes. Advances in Genetics. 80: 37-97. PMID 23084873 DOI: 10.1016/B978-0-12-404742-6.00002-8  0.626
2012 Song G, Li Q, Long Y, Hackett PB, Cui Z. Effective expression-independent gene trapping and mutagenesis mediated by Sleeping Beauty transposon. Journal of Genetics and Genomics = Yi Chuan Xue Bao. 39: 503-20. PMID 23021550 DOI: 10.1016/J.Jgg.2012.05.010  0.506
2012 Song G, Li Q, Long Y, Gu Q, Hackett PB, Cui Z. Effective gene trapping mediated by Sleeping Beauty transposon. Plos One. 7: e44123. PMID 22952894 DOI: 10.1371/Journal.Pone.0044123  0.484
2012 Kebriaei P, Huls H, Jena B, Munsell M, Jackson R, Lee DA, Hackett PB, Rondon G, Shpall E, Champlin RE, Cooper LJ. Infusing CD19-directed T cells to augment disease control in patients undergoing autologous hematopoietic stem-cell transplantation for advanced B-lymphoid malignancies. Human Gene Therapy. 23: 444-50. PMID 22107246 DOI: 10.1089/Hum.2011.167  0.352
2012 Aronovich E, Bell J, Podetz-Petersen K, Koniar B, McIvor RS, Hackett P. Prolonged High-Level Expression of IDUA from Sleeping Beauty Transposons in Immunocompetent Mice Molecular Genetics and Metabolism. 105: S18. DOI: 10.1016/J.Ymgme.2011.11.020  0.355
2012 Ang S, Maiti S, Moriarity B, Andrews K, Ossowski M, Tzeng K, Talbot R, Kellar D, Huls H, Kebriaei P, Kelly S, Shpall E, Largaespada D, Champlin R, Hackett P, et al. Assessing Sleeping Beauty Transpositions for T-Cell Immunotherapy by Supercomputer-Based High-Throughput Profiling of Integration Events Biology of Blood and Marrow Transplantation. 18: S219. DOI: 10.1016/J.Bbmt.2011.12.046  0.328
2011 Hackett PB, Aronovich EL, Hunter D, Urness M, Bell JB, Kass SJ, Cooper LJN, McIvor S. Efficacy and safety of sleeping beauty transposon-mediated gene transfer in preclinical animal studies Current Gene Therapy. 11: 341-349. PMID 21888621 DOI: 10.2174/156652311797415827  0.461
2011 Hyland KA, Olson ER, Clark KJ, Aronovich EL, Hackett PB, Blazar BR, Tolar J, Scott McIvor R. Sleeping Beauty-mediated correction of Fanconi anemia type C. The Journal of Gene Medicine. 13: 462-9. PMID 21766398 DOI: 10.1002/Jgm.1589  0.656
2011 Multhaup MM, Gurram S, Podetz-Pedersen KM, Karlen AD, Swanson DL, Somia NV, Hackett PB, Cowan MJ, McIvor RS. Characterization of the human artemis promoter by heterologous gene expression in vitro and in vivo. Dna and Cell Biology. 30: 751-61. PMID 21663454 DOI: 10.1089/Dna.2011.1244  0.482
2011 Aronovich EL, McIvor RS, Hackett PB. The Sleeping Beauty transposon system: a non-viral vector for gene therapy. Human Molecular Genetics. 20: R14-20. PMID 21459777 DOI: 10.1093/Hmg/Ddr140  0.446
2011 Carlson DF, Garbe JR, Tan W, Martin MJ, Dobrinsky JR, Hackett PB, Clark KJ, Fahrenkrug SC. Strategies for selection marker-free swine transgenesis using the Sleeping Beauty transposon system. Transgenic Research. 20: 1125-37. PMID 21221779 DOI: 10.1007/S11248-010-9481-7  0.785
2011 Ang SO, Maiti S, Moriarity B, Ossowski M, Andrews K, Tzeng K, Talbot R, Kellar D, Huls H, Kebriaei P, Largaespada DA, Champlin R, Hackett P, Cooper LJN. Assessing Potential Genotoxicity of Sleeping Beauty Transposition Events in T-Cell Immunotherapy by Supercomputer-Based High Throughput Profiling, Blood. 118: 4174-4174. DOI: 10.1182/Blood.V118.21.4174.4174  0.39
2010 Wang Y, Kaiser MS, Larson JD, Nasevicius A, Clark KJ, Wadman SA, Roberg-Perez SE, Ekker SC, Hackett PB, McGrail M, Essner JJ. Moesin1 and Ve-cadherin are required in endothelial cells during in vivo tubulogenesis. Development (Cambridge, England). 137: 3119-28. PMID 20736288 DOI: 10.1242/Dev.048785  0.684
2010 Izsvák Z, Hackett PB, Cooper LJ, Ivics Z. Translating Sleeping Beauty transposition into cellular therapies: victories and challenges. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 32: 756-67. PMID 20652893 DOI: 10.1002/Bies.201000027  0.462
2010 Bell JB, Aronovich EL, Schreifels JM, Beadnell TC, Hackett PB. Duration of expression and activity of Sleeping Beauty transposase in mouse liver following hydrodynamic DNA delivery. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 1796-802. PMID 20628359 DOI: 10.1038/Mt.2010.152  0.499
2010 Nesmelova IV, Hackett PB. DDE transposases: Structural similarity and diversity. Advanced Drug Delivery Reviews. 62: 1187-95. PMID 20615441 DOI: 10.1016/J.Addr.2010.06.006  0.302
2010 Fahrenkrug SC, Blake A, Carlson DF, Doran T, Van Eenennaam A, Faber D, Galli C, Gao Q, Hackett PB, Li N, Maga EA, Muir WM, Murray JD, Shi D, Stotish R, et al. Precision genetics for complex objectives in animal agriculture. Journal of Animal Science. 88: 2530-9. PMID 20228236 DOI: 10.2527/Jas.2010-2847  0.602
2010 Hackett PB, Largaespada DA, Cooper LJ. A transposon and transposase system for human application. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 674-83. PMID 20104209 DOI: 10.1038/Mt.2010.2  0.429
2010 Podetz-Pedersen KM, Bell JB, Steele TW, Wilber A, Shier WT, Belur LR, McIvor RS, Hackett PB. Gene expression in lung and liver after intravenous infusion of polyethylenimine complexes of Sleeping Beauty transposons. Human Gene Therapy. 21: 210-20. PMID 19761403 DOI: 10.1089/Hum.2009.128  0.469
2010 Hackett P, Urness M, Bell J, Aronovich E, Olson E, Hunter D, Mcivor S. 54. Hydrodynamic delivery of Sleeping Beauty transposons to canine liver via balloon catheters Molecular Genetics and Metabolism. 99: S19. DOI: 10.1016/J.Ymgme.2009.10.071  0.319
2009 Kalén M, Wallgard E, Asker N, Nasevicius A, Athley E, Billgren E, Larson JD, Wadman SA, Norseng E, Clark KJ, He L, Karlsson-Lindahl L, Häger AK, Weber H, Augustin H, ... ... Hackett PB, et al. Combination of reverse and chemical genetic screens reveals angiogenesis inhibitors and targets. Chemistry & Biology. 16: 432-41. PMID 19389629 DOI: 10.1016/J.Chembiol.2009.02.010  0.609
2009 Aronovich EL, Bell JB, Khan SA, Belur LR, Gunther R, Koniar B, Schachern PA, Parker JB, Carlson CS, Whitley CB, McIvor RS, Gupta P, Hackett PB. Systemic correction of storage disease in MPS I NOD/SCID mice using the sleeping beauty transposon system. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 1136-44. PMID 19384290 DOI: 10.1038/Mt.2009.87  0.402
2009 Hackett P, Aronovich E, Bell J, Khan S, Gunther R, Parker J, Carlson C, Whitley C, Scott McIvor R, Gupta P. 65. Gene therapy of MPS I mice using the Sleeping Beauty Transposon system Molecular Genetics and Metabolism. 96: S26. DOI: 10.1016/J.Ymgme.2008.11.066  0.395
2008 Kurtti TJ, Mattila JT, Herron MJ, Felsheim RF, Baldridge GD, Burkhardt NY, Blazar BR, Hackett PB, Meyer JM, Munderloh UG. Transgene expression and silencing in a tick cell line: A model system for functional tick genomics. Insect Biochemistry and Molecular Biology. 38: 963-8. PMID 18722527 DOI: 10.1016/J.Ibmb.2008.07.008  0.439
2008 Singh H, Manuri PR, Olivares S, Dara N, Dawson MJ, Huls H, Hackett PB, Kohn DB, Shpall EJ, Champlin RE, Cooper LJ. Redirecting specificity of T-cell populations for CD19 using the Sleeping Beauty system. Cancer Research. 68: 2961-71. PMID 18413766 DOI: 10.1158/0008-5472.Can-07-5600  0.363
2008 McIvor RS, Low WC, Hackett PB, Whitley CB. 70. Gene therapy for lysosomal storage disorders Molecular Genetics and Metabolism. 93: 32. DOI: 10.1016/J.Ymgme.2007.10.082  0.321
2008 Low W, Burns T, Verfaillie C, Hackett P, Whitley C, Nan Z, Xiao F, Belur L, Demorest Z, Wolf D, Ohlfest J, McIvor S. 64. Targeting neural stem cells in the mammalian brain with intraventricular injections of lenti, AAV5, or Sleeping Beauty vectors Molecular Genetics and Metabolism. 93: 30. DOI: 10.1016/J.Ymgme.2007.10.076  0.331
2008 Hackett P, Podetz-Pedersen K, Bell J, Aronovich E, Kren B, Whitley C, Driessen W, Sullivan S, McIvor RS. 37. Comparison of gene expression in vivo from Sleeping Beauty transposons after hydrodynamic delivery or condensation by polyethylenimine and cationic lipids Molecular Genetics and Metabolism. 93: 23. DOI: 10.1016/J.Ymgme.2007.10.049  0.426
2008 Aronovich E, Bell J, Belur L, Gunther R, Brenda K, Kahn S, Schachern P, Ehlenfeldt R, Gupta P, Carlson C, Whitley C, McIvor RS, Hackett P. 4. Sleeping Beauty transposon-mediated long-term α-l-iduronidase expression and correction of lysosomal pathology in NOD/SCID mice with MPS I Molecular Genetics and Metabolism. 93: 15. DOI: 10.1016/J.Ymgme.2007.10.016  0.334
2007 Bell JB, Podetz-Pedersen KM, Aronovich EL, Belur LR, McIvor RS, Hackett PB. Preferential delivery of the Sleeping Beauty transposon system to livers of mice by hydrodynamic injection. Nature Protocols. 2: 3153-65. PMID 18079715 DOI: 10.1038/Nprot.2007.471  0.449
2007 Hackett CS, Geurts AM, Hackett PB. Predicting preferential DNA vector insertion sites: implications for functional genomics and gene therapy. Genome Biology. 8: S12. PMID 18047689 DOI: 10.1186/Gb-2007-8-S1-S12  0.479
2007 Aronovich EL, Bell JB, Belur LR, Gunther R, Koniar B, Erickson DC, Schachern PA, Matise I, McIvor RS, Whitley CB, Hackett PB. Prolonged expression of a lysosomal enzyme in mouse liver after Sleeping Beauty transposon-mediated gene delivery: implications for non-viral gene therapy of mucopolysaccharidoses. The Journal of Gene Medicine. 9: 403-15. PMID 17407189 DOI: 10.1002/Jgm.1028  0.473
2007 Hackett PB. Integrating DNA vectors for gene therapy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 10-2. PMID 17164769 DOI: 10.1038/Sj.Mt.6300065  0.422
2007 Singh H, Manuri PR, Olivares S, Dara N, Dawson MJ, Huls H, Lee DA, Hackett PB, Kohn DB, Kebriaei P, Shpall EJ, Champlin R, Cooper L. CD19-Specific T Cells for Treatment of Pediatric Acute Lymphocytic Leukemia Using Sleeping Beauty Transposition. Blood. 110: 2820-2820. DOI: 10.1182/Blood.V110.11.2820.2820  0.377
2007 Hackett P, Bell JB, Aronovich EL. 16 The Sleeping Beauty Transposon system for treatment of mucopolysaccharidoses Molecular Genetics and Metabolism. 92: 15. DOI: 10.1016/J.Ymgme.2007.08.021  0.307
2006 Score PR, Belur LR, Frandsen JL, Geurts JL, Yamaguchi T, Somia NV, Hackett PB, Largaespada DA, McIvor RS. Erratum to "Sleeping Beauty-Mediated Transposition and Long-Term Expression in Vivo: Use of the LoxP/Cre Recombinase System to Distinguish Transposition-Specific Expression". Molecular Therapy : the Journal of the American Society of Gene Therapy. 14: 149. PMID 28192690 DOI: 10.1016/J.Ymthe.2006.03.011  0.388
2006 Balciunas D, Wangensteen KJ, Wilber A, Bell J, Geurts A, Sivasubbu S, Wang X, Hackett PB, Largaespada DA, McIvor RS, Ekker SC. Harnessing a high cargo-capacity transposon for genetic applications in vertebrates. Plos Genetics. 2: e169. PMID 17096595 DOI: 10.1371/Journal.Pgen.0020169  0.652
2006 Geurts AM, Wilber A, Carlson CM, Lobitz PD, Clark KJ, Hackett PB, McIvor RS, Largaespada DA. Conditional gene expression in the mouse using a Sleeping Beauty gene-trap transposon. Bmc Biotechnology. 6: 30. PMID 16800892 DOI: 10.1186/1472-6750-6-30  0.702
2006 Geurts AM, Hackett CS, Bell JB, Bergemann TL, Collier LS, Carlson CM, Largaespada DA, Hackett PB. Structure-based prediction of insertion-site preferences of transposons into chromosomes. Nucleic Acids Research. 34: 2803-11. PMID 16717285 DOI: 10.1093/Nar/Gkl301  0.425
2006 Wilber A, Frandsen JL, Geurts JL, Largaespada DA, Hackett PB, McIvor RS. RNA as a source of transposase for Sleeping Beauty-mediated gene insertion and expression in somatic cells and tissues. Molecular Therapy : the Journal of the American Society of Gene Therapy. 13: 625-30. PMID 16368272 DOI: 10.1016/J.Ymthe.2005.10.014  0.493
2006 Score PR, Belur LR, Frandsen JL, Geurts JL, Guerts JL, Yamaguchi T, Somia NV, Hackett PB, Largaespada DA, McIvor RS. Sleeping Beauty-mediated transposition and long-term expression in vivo: use of the LoxP/Cre recombinase system to distinguish transposition-specific expression. Molecular Therapy : the Journal of the American Society of Gene Therapy. 13: 617-24. PMID 16356773 DOI: 10.1016/J.Ymthe.2005.10.015  0.489
2006 Geurts AM, Hackett CS, Bell JB, Bergemann TL, Collier LS, Carlson CM, Largaespada DA, Hackett PB. 520. ProTIS, a Method for Prediction of Insertion-Site Preferences into Chromosomes of Vectors Used for Gene Therapy Molecular Therapy. 13: S200. DOI: 10.1016/J.Ymthe.2006.08.591  0.404
2006 Bell JB, Aronovich EL, Koniar BL, Schreifels JM, Clifford AM, Hoekstra ND, Hackett PB. 392. Duration of Expression of the Sleeping Beauty Transposase Gene in Mouse Liver Following Hydrodynamic Delivery Molecular Therapy. 13: S150. DOI: 10.1016/J.Ymthe.2006.08.453  0.494
2006 Balciunas D, Wilber A, Wangensteen K, Bell J, Geurts A, Hackett PB, Largaespada DA, McIvor RS, Ekker SC. 385. Tol2 Transposon as a Gene Therapy Vector: Characterization, Optimization and Correction of Hereditary Tyrosinemia Type 1 in Mouse Molecular Therapy. 13: S147. DOI: 10.1016/J.Ymthe.2006.08.446  0.64
2006 Aronovich EL, Bell JB, Belur LR, Gunther R, Koniar B, Erickson DC, Schachern PA, Scott McIvor R, Whitley CB, Hackett PB. 208. Sleeping Beauty Transposon-Mediated Long-Term α-L-iduronidase Expression and Correction of Lysosomal Pathology in the Murine Model of Mucopolysaccharidosis (MPS) Type I Molecular Therapy. 13: S80-S81. DOI: 10.1016/J.Ymthe.2006.08.233  0.376
2006 Podetz-Pedersen KM, Bell JB, Steele TW, Frandsen JL, Shier TW, McIvor RS, Hackett PB. 181. Quantitative Evaluation of Long Term Gene Expression In Vivo after Delivery of Polyethylenimine-Conjugated Sleeping Beauty Transposon DNA Molecular Therapy. 13: S70. DOI: 10.1016/J.Ymthe.2006.08.205  0.415
2006 Aronnovich EL, Bell JB, Gunther R, Koniar B, Frantz A, Matise I, McIvor RS, Whitley CB, Hackett PB. 997. Immune-Mediated Loss of Transgene Expression in Mouse Liver Following Transposon Delivery Molecular Therapy. 13: S384. DOI: 10.1016/J.Ymthe.2006.08.1090  0.441
2006 Belur LR, Buske T, Sorensen B, Podetz-Peterson K, Saltzman D, Hackett PB, Scott McIvor R. 958. Sleeping Beauty-Mediated Gene Therapy for Colorectal Cancer Molecular Therapy. 13: S369. DOI: 10.1016/J.Ymthe.2006.08.1050  0.447
2005 Hackett PB, Ekker SC, Largaespada DA, McIvor RS. Sleeping beauty transposon-mediated gene therapy for prolonged expression. Advances in Genetics. 54: 189-232. PMID 16096013 DOI: 10.1016/S0065-2660(05)54009-4  0.673
2005 Essner JJ, McIvor RS, Hackett PB. Awakening gene therapy with Sleeping Beauty transposons. Current Opinion in Pharmacology. 5: 513-9. PMID 16084771 DOI: 10.1016/J.Coph.2005.04.015  0.418
2005 Wadman SA, Clark KJ, Hackett PB. Fishing for answers with transposons. Marine Biotechnology (New York, N.Y.). 7: 135-41. PMID 15864468 DOI: 10.1007/S10126-004-0068-2  0.703
2005 Liu G, Geurts AM, Yae K, Srinivasan AR, Fahrenkrug SC, Largaespada DA, Takeda J, Horie K, Olson WK, Hackett PB. Target-site preferences of Sleeping Beauty transposons. Journal of Molecular Biology. 346: 161-73. PMID 15663935 DOI: 10.1016/J.Jmb.2004.09.086  0.729
2005 Ohlfest JR, Frandsen JL, Fritz S, Lobitz PD, Perkinson SG, Clark KJ, Nelsestuen G, Key NS, McIvor RS, Hackett PB, Largaespada DA. Phenotypic correction and long-term expression of factor VIII in hemophilic mice by immunotolerization and nonviral gene transfer using the Sleeping Beauty transposon system. Blood. 105: 2691-8. PMID 15576475 DOI: 10.1182/Blood-2004-09-3496  0.708
2005 Wadman SA, Clark KJ, Hackett PB, McIvor RS, Essner JJ. 347. Long-Term Gene Expression and Phenotypic Correction of FANCC Deficient Lymphoblastoid Cells Using the Sleeping Beauty Transposon System Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.350  0.703
2005 Liu LN, Essner JJ, Shivakumar R, Li L, Wadman SA, Clark KJ, Nasevicious A, Fratantoni JC, McIvor RS, Hackett PB. 192. Non-Viral, Long-Term Gene Expression in Hematopoietic Cells Using the Sleeping Beauty Transposon System Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.195  0.697
2005 Bell JB, Hackett CS, Geurts AM, Carlson CM, Collier LS, Liu G, Largaespada DA, Hackett PB. 176. Target-Site Preferences of Sleeping Beauty Transposons in an Intron of the B-raf Oncogene Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.179  0.577
2004 Converse AD, Belur LR, Gori JL, Liu G, Amaya F, Aguilar-Cordova E, Hackett PB, McIvor RS. Counterselection and co-delivery of transposon and transposase functions for Sleeping Beauty-mediated transposition in cultured mammalian cells. Bioscience Reports. 24: 577-94. PMID 16158196 DOI: 10.1007/S10540-005-2793-9  0.651
2004 Larson JD, Wadman SA, Chen E, Kerley L, Clark KJ, Eide M, Lippert S, Nasevicius A, Ekker SC, Hackett PB, Essner JJ. Expression of VE-cadherin in zebrafish embryos: a new tool to evaluate vascular development. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 231: 204-13. PMID 15305301 DOI: 10.1002/Dvdy.20102  0.695
2004 Clark KJ, Geurts AM, Bell JB, Hackett PB. Transposon vectors for gene-trap insertional mutagenesis in vertebrates. Genesis (New York, N.Y. : 2000). 39: 225-33. PMID 15286994 DOI: 10.1002/Gene.20049  0.7
2004 Liu G, Aronovich EL, Cui Z, Whitley CB, Hackett PB. Excision of Sleeping Beauty transposons: parameters and applications to gene therapy. The Journal of Gene Medicine. 6: 574-83. PMID 15133768 DOI: 10.1002/Jgm.486  0.642
2004 Bell JB, Aronovich EL, Larson-DeBruzzi BE, Koniar BL, Gunther R, Whitley CB, McIvor RS, Hackett PB. 1098. Duration of Expression of Sleeping Beauty Transposase by Hydrodynamic Injection of C57/BL6 Mice Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2005.07.646  0.479
2004 Wilber AC, Frandsen JL, Belur LR, Score PR, Geurts JL, Largaespada DA, Hackett PB, McIvor RS. 1042. RNA as a Source of Transposase for Sleeping Beauty-Mediated Transposition and Long-Term Expression in Somatic Cells and Tissues Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.987  0.5
2004 Aronovich EL, Bell JB, Belur LR, Fransden JL, Gunther R, Koniar B, Erickson DCC, McIvor RS, Hackett PB, Whitley CB. 871. Long-Term Expression of Sleeping Beauty Transposon in the Murine Model of Mucopolysaccharidosis (MPS) Type VII Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.778  0.423
2004 Score PR, Frandsen JL, Geurts JL, Hackett PB, Largaespada DA, McIvor RS. 823. Use of a Cre Recombinase Silencing Strategy to Characterize Sleeping Beauty-Mediated Transposition In Vivo Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.720  0.509
2004 Ohlfest JR, Perkinson S, Lobitz P, Frandsen J, McIvor RS, Hackett P, Clark K, Essner J, Key N, Largaespada DA. 165. Long-term factor VIII expression and phenotypic correction in a murine model of hemophilia A achieved by immunosuppression and non-viral gene transfer using the sleeping beauty transposon Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.125  0.692
2003 Davidson AE, Balciunas D, Mohn D, Shaffer J, Hermanson S, Sivasubbu S, Cliff MP, Hackett PB, Ekker SC. Efficient gene delivery and gene expression in zebrafish using the Sleeping Beauty transposon. Developmental Biology. 263: 191-202. PMID 14597195 DOI: 10.1016/J.Ydbio.2003.07.013  0.676
2003 Belur LR, Frandsen JL, Dupuy AJ, Ingbar DH, Largaespada DA, Hackett PB, Scott McIvor R. Gene insertion and long-term expression in lung mediated by the Sleeping Beauty transposon system. Molecular Therapy : the Journal of the American Society of Gene Therapy. 8: 501-7. PMID 12946324 DOI: 10.1016/S1525-0016(03)00211-9  0.434
2003 Cui Z, Yang Y, Kaufman CD, Agalliu D, Hackett PB. RecA-mediated, targeted mutagenesis in zebrafish. Marine Biotechnology (New York, N.Y.). 5: 174-84. PMID 12876654 DOI: 10.1007/S10126-002-0059-0  0.424
2003 Geurts AM, Yang Y, Clark KJ, Liu G, Cui Z, Dupuy AJ, Bell JB, Largaespada DA, Hackett PB. Gene transfer into genomes of human cells by the sleeping beauty transposon system. Molecular Therapy : the Journal of the American Society of Gene Therapy. 8: 108-17. PMID 12842434 DOI: 10.1016/S1525-0016(03)00099-6  0.755
2002 Cui Z, Geurts AM, Liu G, Kaufman CD, Hackett PB. Structure-function analysis of the inverted terminal repeats of the sleeping beauty transposon. Journal of Molecular Biology. 318: 1221-35. PMID 12083513 DOI: 10.1016/S0022-2836(02)00237-1  0.585
2002 Dupuy AJ, Clark K, Carlson CM, Fritz S, Davidson AE, Markley KM, Finley K, Fletcher CF, Ekker SC, Hackett PB, Horn S, Largaespada DA. Mammalian germ-line transgenesis by transposition. Proceedings of the National Academy of Sciences of the United States of America. 99: 4495-9. PMID 11904379 DOI: 10.1073/Pnas.062630599  0.73
2001 Karsi A, Moav B, Hackett P, Liu Z. Effects of insert size on transposition efficiency of the sleeping beauty transposon in mouse cells. Marine Biotechnology (New York, N.Y.). 3: 241-5. PMID 14961361 DOI: 10.1007/S101260000072  0.445
2001 Cui Z, Clark KJ, Kaufman CD, Hackett PB. Inhibition of skiA and skiB gene expression ventralizes zebrafish embryos. Genesis (New York, N.Y. : 2000). 30: 149-53. PMID 11477695 DOI: 10.1002/Gene.1052  0.633
2001 Fahrenkrug SC, Joshi B, Hackett PB, Jagus R. Alternative transcriptional initiation and splicing define the translational efficiencies of zebrafish mRNAs encoding eukaryotic initiation factor 4E. Differentiation; Research in Biological Diversity. 66: 15-22. PMID 10997588 DOI: 10.1046/J.1432-0436.2000.066001015.X  0.628
2000 Kaufman CD, Martínez-Rodriguez G, Hackett PB. Ectopic expression of c-ski disrupts gastrulation and neural patterning in zebrafish. Mechanisms of Development. 95: 147-62. PMID 10906458 DOI: 10.1016/S0925-4773(00)00351-8  0.336
1999 Caldovic L, Agalliu D, Hackett PB. Position-independent expression of transgenes in zebrafish. Transgenic Research. 8: 321-34. PMID 10669943 DOI: 10.1023/A:1008993022331  0.435
1999 Fahrenkrug SC, Dahlquist MO, Clark KJ, Hackett PB. Dynamic and tissue-specific expression of eIF4E during zebrafish embryogenesis Differentiation. 65: 191-201. PMID 10653355 DOI: 10.1046/J.1432-0436.1999.6540191.X  0.751
1999 Fahrenkrug SC, Clark KJ, Dahlquist MO, Hackett PB. Dicistronic Gene Expression in Developing Zebrafish. Marine Biotechnology (New York, N.Y.). 1: 552-561. PMID 10612680 DOI: 10.1007/Pl00011810  0.76
1999 Ivics Z, Izsvák Z, Hackett PB. Genetic applications of transposons and other repetitive elements in zebrafish. Methods in Cell Biology. 60: 99-131. PMID 9891333 DOI: 10.1016/S0091-679X(08)61896-8  0.402
1999 Izsvák Z, Ivics Z, Shimoda N, Mohn D, Okamoto H, Hackett PB. Short inverted-repeat transposable elements in teleost fish and implications for a mechanism of their amplification. Journal of Molecular Evolution. 48: 13-21. PMID 9873073 DOI: 10.1007/Pl00006440  0.355
1997 Essner JJ, Breuer JJ, Essner RD, Fahrenkrug SC, Hackett PB. The zebrafish thyroid hormone receptor alpha 1 is expressed during early embryogenesis and can function in transcriptional repression. Differentiation; Research in Biological Diversity. 62: 107-17. PMID 9447705 DOI: 10.1046/J.1432-0436.1997.6230107.X  0.603
1997 Ivics Z, Hackett PB, Plasterk RH, Izsvák Z. Molecular reconstruction of sleeping beauty, a Tc1-like transposon from fish, and its transposition in human cells Cell. 91: 501-510. PMID 9390559 DOI: 10.1016/S0092-8674(00)80436-5  0.422
1997 Izsvák Z, Ivics Z, Hackett PB. Repetitive elements and their genetic applications in zebrafish Biochemistry and Cell Biology. 75: 507-523. DOI: 10.1139/O97-045  0.425
1996 Essner JJ, Laing JG, Beyer EC, Johnson RG, Hackett PB. Expression of zebrafish connexin43.4 in the notochord and tail bud of wild-type and mutant no tail embryos. Developmental Biology. 177: 449-62. PMID 8806823 DOI: 10.1006/Dbio.1996.0177  0.398
1996 Izsvák Z, Ivics Z, Garcia-Estefania D, Fahrenkrug SC, Hackett PB. DANA elements: a family of composite, tRNA-derived short interspersed DNA elements associated with mutational activities in zebrafish (Danio rerio). Proceedings of the National Academy of Sciences of the United States of America. 93: 1077-81. PMID 8577717 DOI: 10.1073/Pnas.93.3.1077  0.64
1995 Izsvák Z, Ivics Z, Hackett PB. Characterization of a Tc1-like transposable element in zebrafish (Danio rerio). Molecular & General Genetics : Mgg. 247: 312-22. PMID 7770036 DOI: 10.1007/Bf00293199  0.363
1993 Liu Z, Hackett PB. Reverse cloning procedure for generation of subclones for DNA sequencing. Methods in Enzymology. 218: 47-58. PMID 8389968 DOI: 10.1016/0076-6879(93)18007-Y  0.308
1993 Moav B, Liu Z, Caldovic LD, Gross ML, Faras AJ, Hackett PB. Regulation of expression of transgenes in developing fish. Transgenic Research. 2: 153-61. PMID 8353534 DOI: 10.1007/Bf01972609  0.425
1992 Gross ML, Schneider JF, Moav N, Moav B, Alvarez C, Myster SH, Liu Z, Hallerman EM, Hackett PB, Guise KS, Faras AJ, Kapuscinski AR. Molecular analysis and growth evaluation of northern pike (Esox Iucius) microinjected with growth hormone genes Aquaculture. 103: 253-273. DOI: 10.1016/0044-8486(92)90171-G  0.327
1991 Liu Z, Moav B, Faras AJ, Guise KS, Kapuscinski AR, Hackett P. Importance of the CArG box in regulation of β-actin-encoding genes Gene. 108: 211-217. PMID 1748307 DOI: 10.1016/0378-1119(91)90436-F  0.4
1990 Liu Z, Moav B, Faras AJ, Guise KS, Kapuscinski AR, Hackett PB. Functional Analysis of Elements Affecting Expression of the β-Actin Gene of Carp Molecular and Cellular Biology. 10: 3432-3440. PMID 2355913 DOI: 10.1128/Mcb.10.7.3432  0.416
1990 Hallerman EM, Schneider JF, Gross M, He L, Kapuscinski AR, Liu Z, Yoon SJ, Hackett PB, Faras AJ, Guise KS. Gene Expression Promoted by The RSV Long Terminal Repeat Eiement in Transgenic Goldfish Animal Biotechnology. 1: 79-93. DOI: 10.1080/10495399009525731  0.378
1990 Liu Z, Moav B, Faras AJ, Guise KS, Kapuscinski AR, Hackett PB. Development of expression vectors for transgenic fish Nature Biotechnology. 8: 1268-1272. DOI: 10.1038/Nbt1290-1268  0.414
1990 Yoon SJ, Hallerman EM, Gross ML, Liu Z, Schneider JF, Faras AJ, Hackett PB, Kapuscinski AR, Guise KS. Transfer of the gene for neomycin resistance into goldfish, Carassius auratus Aquaculture. 85: 21-33. DOI: 10.1016/0044-8486(90)90004-7  0.436
1989 Jacks CM, Powaser CB, Hackett PB. Sequence analysis of a processed gene coding for mouse ribosomal protein L32. Gene. 74: 565-70. PMID 3246356 DOI: 10.1016/0378-1119(88)90191-6  0.347
1989 Liu ZJ, Hackett PB. Sequence variation of the Rous sarcoma virus PrA src gene. Nucleic Acids Research. 17: 3986. PMID 2543959 DOI: 10.1093/Nar/17.10.3986  0.352
1989 Jacks CM, Biltz RE, Hackett PB. Analysis of potential expression of highly related members of the ribosomal protein L32 gene family. Nucleic Acids Research. 16: 10751-64. PMID 2462715 DOI: 10.1093/Nar/16.22.10751  0.35
1985 Mulligan PK, Hackett PB. Isolation of a mouse DNA fragment with homology to a Drosophila ribosomal protein gene. Gene. 34: 155-61. PMID 2989106 DOI: 10.1016/0378-1119(85)90123-4  0.432
1974 Hackett PB, Sauerbier W. Radiological mapping of the ribosomal RNA transcription unit in E. coli. Nature. 251: 639-641. PMID 4608761 DOI: 10.1038/251639A0  0.303
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