Lisa Coussens - Publications

Affiliations: 
University of California, San Francisco, San Francisco, CA 
Area:
Cell Biology, Oncology

124 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Doha ZO, Wang X, Calistri NL, Eng J, Daniel CJ, Ternes L, Kim EN, Pelz C, Munks M, Betts C, Kwon S, Bucher E, Li X, Waugh T, Tatarova Z, ... ... Coussens LM, et al. MYC Deregulation and PTEN Loss Model Tumor and Stromal Heterogeneity of Aggressive Triple-Negative Breast Cancer. Nature Communications. 14: 5665. PMID 37704631 DOI: 10.1038/s41467-023-40841-6  0.369
2023 Steele MM, Jaiswal A, Delclaux I, Dryg ID, Murugan D, Femel J, Son S, du Bois H, Hill C, Leachman SA, Chang YH, Coussens LM, Anandasabapathy N, Lund AW. T cell egress via lymphatic vessels is tuned by antigen encounter and limits tumor control. Nature Immunology. PMID 36849745 DOI: 10.1038/s41590-023-01443-y  0.335
2022 Mi H, Sivagnanam S, Betts CB, Liudahl SM, Jaffee EM, Coussens LM, Popel AS. Quantitative Spatial Profiling of Immune Populations in Pancreatic Ductal Adenocarcinoma Reveals Tumor Microenvironment Heterogeneity and Prognostic Biomarkers. Cancer Research. PMID 36112643 DOI: 10.1158/0008-5472.CAN-22-1190  0.307
2022 Abrego J, Sanford-Crane H, Oon C, Xiao X, Betts CB, Sun D, Nagarajan S, Diaz L, Sandborg H, Bhattacharyya S, Xia Z, Coussens LM, Tontonoz P, Sherman MH. A cancer cell-intrinsic GOT2-PPARd axis suppresses antitumor immunity. Cancer Discovery. PMID 35894778 DOI: 10.1158/2159-8290.CD-22-0661  0.374
2022 Tatarova Z, Blumberg DC, Korkola JE, Heiser LM, Muschler JL, Schedin PJ, Ahn SW, Mills GB, Coussens LM, Jonas O, Gray JW. A multiplex implantable microdevice assay identifies synergistic combinations of cancer immunotherapies and conventional drugs. Nature Biotechnology. PMID 35788566 DOI: 10.1038/s41587-022-01379-y  0.366
2022 Sundaram S, Kim EN, Jones GM, Sivagnanam S, Tripathi M, Miremadi A, Di Pietro M, Coussens LM, Fitzgerald RC, Chang YH, Zhuang L. Deciphering the Immune Complexity in Esophageal Adenocarcinoma and Pre-Cancerous Lesions With Sequential Multiplex Immunohistochemistry and Sparse Subspace Clustering Approach. Frontiers in Immunology. 13: 874255. PMID 35663986 DOI: 10.3389/fimmu.2022.874255  0.323
2022 Johnson BE, Creason AL, Stommel JM, Keck JM, Parmar S, Betts CB, Blucher A, Boniface C, Bucher E, Burlingame E, Camp T, Chin K, Eng J, Estabrook J, Feiler HS, ... ... Coussens LM, et al. An omic and multidimensional spatial atlas from serial biopsies of an evolving metastatic breast cancer. Cell Reports. Medicine. 3: 100525. PMID 35243422 DOI: 10.1016/j.xcrm.2022.100525  0.3
2022 Blise KE, Sivagnanam S, Banik GL, Coussens LM, Goecks J. Single-cell spatial architectures associated with clinical outcome in head and neck squamous cell carcinoma. Npj Precision Oncology. 6: 10. PMID 35217711 DOI: 10.1038/s41698-022-00253-z  0.366
2021 Yoshimura K, Tsujikawa T, Mitsuda J, Ogi H, Saburi S, Ohmura G, Arai A, Shibata S, Thibault G, Chang YH, Clayburgh DR, Yasukawa S, Miyagawa-Hayashino A, Konishi E, Itoh K, ... Coussens LM, et al. Spatial Profiles of Intratumoral PD-1 Helper T Cells Predict Prognosis in Head and Neck Squamous Cell Carcinoma. Frontiers in Immunology. 12: 769534. PMID 34777389 DOI: 10.3389/fimmu.2021.769534  0.332
2021 Labrie M, Li A, Creason A, Betts C, Keck J, Johnson B, Sivagnanam S, Boniface C, Ma H, Blucher A, Chang YH, Chin K, Vuky J, Guimaraes AR, Downey M, ... ... Coussens LM, et al. Multiomics analysis of serial PARP inhibitor treated metastatic TNBC inform on rational combination therapies. Npj Precision Oncology. 5: 92. PMID 34667258 DOI: 10.1038/s41698-021-00232-w  0.408
2021 Pucci F, Coussens LM. Redirecting tumor macrophage activity to fight cancer: Make room for the next era of anti-cancer drugs. Cancer Cell. 39: 1300-1302. PMID 34637745 DOI: 10.1016/j.ccell.2021.09.009  0.393
2021 Gatti G, Betts C, Rocha D, Nicola M, Grupe V, Ditada C, Nuñez NG, Roselli E, Araya P, Dutto J, Boffelli L, Fernández E, Coussens LM, Maccioni M. High IRF8 expression correlates with CD8 T cell infiltration and is a predictive biomarker of therapy response in ER-negative breast cancer. Breast Cancer Research : Bcr. 23: 40. PMID 33766090 DOI: 10.1186/s13058-021-01418-7  0.437
2021 Liudahl SM, Betts CB, Sivagnanam S, Morales-Oyarvide V, da Silva A, Yuan C, Hwang S, Grossblatt-Wait A, Leis KR, Larson W, Lavoie MB, Robinson P, Dias Costa A, Vayrynen SA, Clancy TE, ... ... Coussens LM, et al. Leukocyte Heterogeneity in Pancreatic Ductal Adenocarcinoma: Phenotypic and Spatial Features Associated with Clinical Outcome. Cancer Discovery. PMID 33727309 DOI: 10.1158/2159-8290.CD-20-0841  0.307
2020 Maller O, Drain AP, Barrett AS, Borgquist S, Ruffell B, Zakharevich I, Pham TT, Gruosso T, Kuasne H, Lakins JN, Acerbi I, Barnes JM, Nemkov T, Chauhan A, Gruenberg J, ... ... Coussens LM, et al. Tumour-associated macrophages drive stromal cell-dependent collagen crosslinking and stiffening to promote breast cancer aggression. Nature Materials. PMID 33257795 DOI: 10.1038/s41563-020-00849-5  0.52
2020 Banik G, Betts CB, Liudahl SM, Sivagnanam S, Kawashima R, Cotechini T, Larson W, Goecks J, Pai SI, Clayburgh DR, Tsujikawa T, Coussens LM. High-dimensional multiplexed immunohistochemical characterization of immune contexture in human cancers. Methods in Enzymology. 635: 1-20. PMID 32122539 DOI: 10.1016/Bs.Mie.2019.05.039  0.434
2020 Li A, Labrie M, Vuky J, Lim JY, Johnson B, Sivagnanam S, Betts C, Coussens L, Corless CL, Bergan RC, Gray JW, Mills GB, Mitri ZI. Feasibility of real-time serial comprehensive tumor analytics: Pilot study of olaparib and durvalumab in metastatic triple negative breast cancer (mTNBC). Journal of Clinical Oncology. 38: e13092-e13092. DOI: 10.1200/Jco.2020.38.15_Suppl.E13092  0.318
2019 Sinha M, Griffith M, Betts C, Choe G, Sivagnanam S, Cheung A, Tamaki W, Liu E, Sudduth-Klinger J, Vaccaro G, Lopez C, Fong L, Coussens L, Tempero M. Immune modulatory effects of ibrutinib in pancreatic ductal adenocarcinoma. Annals of Oncology : Official Journal of the European Society For Medical Oncology. 30: iv40. PMID 32085149 DOI: 10.1093/Annonc/Mdz155.145  0.319
2019 Galliverti G, Wullschleger S, Tichet M, Murugan D, Zangger N, Horton W, Korman AJ, Coussens LM, Swartz MA, Hanahan D. Myeloid cells orchestrate systemic immunosuppression, impairing the efficacy of immunotherapy against HPV+ cancers. Cancer Immunology Research. PMID 31771984 DOI: 10.1158/2326-6066.Cir-19-0315  0.592
2019 Michaelis KA, Norgard MA, Zhu X, Levasseur PR, Sivagnanam S, Liudahl SM, Burfeind KG, Olson B, Pelz KR, Angeles Ramos DM, Maurer HC, Olive KP, Coussens LM, Morgan TK, Marks DL. The TLR7/8 agonist R848 remodels tumor and host responses to promote survival in pancreatic cancer. Nature Communications. 10: 4682. PMID 31615993 DOI: 10.1038/S41467-019-12657-W  0.355
2019 Bedognetti D, Ceccarelli M, Galluzzi L, Lu R, Palucka K, Samayoa J, Spranger S, Warren S, Wong KK, Ziv E, Chowell D, Coussens LM, De Carvalho DD, DeNardo DG, Galon J, et al. Correction to: Toward a comprehensive view of cancer immune responsiveness: a synopsis from the SITC workshop. Journal For Immunotherapy of Cancer. 7: 167. PMID 31272507 DOI: 10.1186/S40425-019-0640-Y  0.581
2019 Vitale I, Manic G, Coussens LM, Kroemer G, Galluzzi L. Macrophages and Metabolism in the Tumor Microenvironment. Cell Metabolism. 30: 36-50. PMID 31269428 DOI: 10.1016/J.Cmet.2019.06.001  0.336
2019 Hundeyin M, Kurz E, Mishra A, Kochen Rossi JA, Liudahl SM, Leis KR, Mehrotra H, Kim M, Torres LE, Ogunsakin A, Link J, Sears RC, Sivagnanam S, Goecks J, Islam KS, ... ... Coussens LM, et al. Innate αβ T cells Mediate Antitumor Immunity by Orchestrating Immunogenic Macrophage Programming. Cancer Discovery. PMID 31266770 DOI: 10.1158/2159-8290.Cd-19-0161  0.384
2019 Hassan R, Alley E, Kindler H, Antonia SJ, Jahan TM, Honarmand S, Nair N, Whiting C, Enstrom A, Lemmens E, Tsujikawa T, Kumar S, Choe G, Thomas A, McDougall K, ... ... Coussens LM, et al. Live-Attenuated, Listeria monocytogenes Expressing Mesothelin (CRS-207) with Chemotherapy for Treatment of Malignant Pleural Mesothelioma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31263030 DOI: 10.1158/1078-0432.Ccr-19-0070  0.331
2019 Bedognetti D, Ceccarelli M, Galluzzi L, Lu R, Palucka K, Samayoa J, Spranger S, Warren S, Wong KK, Ziv E, Chowell D, Coussens LM, De Carvalho DD, DeNardo DG, Galon J, et al. Toward a comprehensive view of cancer immune responsiveness: a synopsis from the SITC workshop. Journal For Immunotherapy of Cancer. 7: 131. PMID 31113486 DOI: 10.1186/S40425-019-0602-4  0.649
2019 Datta M, Coussens LM, Nishikawa H, Hodi FS, Jain RK. Reprogramming the Tumor Microenvironment to Improve Immunotherapy: Emerging Strategies and Combination Therapies. American Society of Clinical Oncology Educational Book. American Society of Clinical Oncology. Annual Meeting. 165-174. PMID 31099649 DOI: 10.1200/EDBK_237987  0.395
2019 Reddy SM, Reuben A, Barua S, Jiang H, Zhang S, Wang L, Gopalakrishnan V, Hudgens CW, Tetzlaff MT, Reuben JM, Tsujikawa T, Coussens LM, Wani K, He Y, Villarreal L, et al. Poor response to neoadjuvant chemotherapy correlates with mast cell infiltration in inflammatory breast cancer. Cancer Immunology Research. PMID 31043414 DOI: 10.1158/2326-6066.Cir-18-0619  0.431
2019 Cassetta L, Fragkogianni S, Sims AH, Swierczak A, Forrester LM, Zhang H, Soong DYH, Cotechini T, Anur P, Lin EY, Fidanza A, Lopez-Yrigoyen M, Millar MR, Urman A, Ai Z, ... ... Coussens LM, et al. Human Tumor-Associated Macrophage and Monocyte Transcriptional Landscapes Reveal Cancer-Specific Reprogramming, Biomarkers, and Therapeutic Targets. Cancer Cell. PMID 30930117 DOI: 10.1016/J.Ccell.2019.02.009  0.362
2019 Coussens L. Abstract BL1: Modeling Immune Response: Lessons Learned from Mouse Models of Cancer Development Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-Bl1  0.552
2019 Dimastromatteo J, Poisonnier A, Perez S, Coussens L, Kelly K. Abstract 1558: Therapeutic targeting of cell surface plectin induces anti-cancer immune response and pancreatic cancer regression Cancer Research. 79: 1558-1558. DOI: 10.1158/1538-7445.Am2019-1558  0.523
2018 Saung MT, Muth S, Ding D, Thomas DL, Blair AB, Tsujikawa T, Coussens L, Jaffee EM, Zheng L. Targeting myeloid-inflamed tumor with anti-CSF-1R antibody expands CD137+ effector T-cells in the murine model of pancreatic cancer. Journal For Immunotherapy of Cancer. 6: 118. PMID 30424804 DOI: 10.1186/S40425-018-0435-6  0.415
2018 Medler TR, Murugan D, Horton W, Kumar S, Cotechini T, Forsyth AM, Leyshock P, Leitenberger JJ, Kulesz-Martin M, Margolin AA, Werb Z, Coussens LM. Complement C5a Fosters Squamous Carcinogenesis and Limits T Cell Response to Chemotherapy. Cancer Cell. 34: 561-578.e6. PMID 30300579 DOI: 10.1016/J.Ccell.2018.09.003  0.54
2018 Pennock ND, Martinson HA, Guo Q, Betts CB, Jindal S, Tsujikawa T, Coussens LM, Borges VF, Schedin P. Ibuprofen supports macrophage differentiation, T cell recruitment, and tumor suppression in a model of postpartum breast cancer. Journal For Immunotherapy of Cancer. 6: 98. PMID 30285905 DOI: 10.1186/S40425-018-0406-Y  0.457
2018 Gast CE, Silk AD, Zarour L, Riegler L, Burkhart JG, Gustafson KT, Parappilly MS, Roh-Johnson M, Goodman JR, Olson B, Schmidt M, Swain JR, Davies PS, Shasthri V, Iizuka S, ... ... Coussens LM, et al. Cell fusion potentiates tumor heterogeneity and reveals circulating hybrid cells that correlate with stage and survival. Science Advances. 4: eaat7828. PMID 30214939 DOI: 10.1126/Sciadv.Aat7828  0.386
2018 Li J, Byrne KT, Yan F, Yamazoe T, Chen Z, Baslan T, Richman LP, Lin JH, Sun YH, Rech AJ, Balli D, Hay CA, Sela Y, Merrell AJ, Liudahl SM, ... ... Coussens LM, et al. Tumor Cell-Intrinsic Factors Underlie Heterogeneity of Immune Cell Infiltration and Response to Immunotherapy. Immunity. PMID 29958801 DOI: 10.1016/J.Immuni.2018.06.006  0.431
2018 Binnewies M, Roberts EW, Kersten K, Chan V, Fearon DF, Merad M, Coussens LM, Gabrilovich DI, Ostrand-Rosenberg S, Hedrick CC, Vonderheide RH, Pittet MJ, Jain RK, Zou W, Howcroft TK, et al. Understanding the tumor immune microenvironment (TIME) for effective therapy. Nature Medicine. PMID 29686425 DOI: 10.1038/S41591-018-0014-X  0.344
2018 de Mingo Pulido Á, Gardner A, Hiebler S, Soliman H, Rugo HS, Krummel MF, Coussens LM, Ruffell B. TIM-3 Regulates CD103+ Dendritic Cell Function and Response to Chemotherapy in Breast Cancer. Cancer Cell. 33: 60-74.e6. PMID 29316433 DOI: 10.1016/J.Ccell.2017.11.019  0.347
2018 Johnson B, Keck J, Morris M, Siex K, Kolodzie A, Parmar S, Riesterer J, Chin K, Gibbs S, Heiser L, Spellman P, Ellrott K, Babur O, Demir E, Margolin A, ... ... Coussens L, et al. Abstract 3296: SMMART: Serial measurements of molecular and architectural responses to therapy Cancer Research. 78: 3296-3296. DOI: 10.1158/1538-7445.Am2018-3296  0.426
2017 Gopalakrishnan V, Spencer CN, Nezi L, Reuben A, Andrews MC, Karpinets TV, Prieto PA, Vicente D, Hoffman K, Wei SC, Cogdill AP, Zhao L, Hudgens CW, Hutchinson DS, Manzo T, ... ... Coussens LM, et al. Gut microbiome modulates response to anti-PD-1 immunotherapy in melanoma patients. Science (New York, N.Y.). PMID 29097493 DOI: 10.1126/Science.Aan4236  0.36
2017 Gast CE, Shaw AK, Wong MH, Coussens LM. Surgical Procedures and Methodology for a Preclinical Murine Model of De Novo Mammary Cancer Metastasis. Journal of Visualized Experiments : Jove. PMID 28784976 DOI: 10.3791/54852  0.374
2017 Gil Del Alcazar CR, Huh SJ, Ekram MB, Trinh A, Liu LL, Beca F, Zi X, Kwak M, Bergholtz H, Su Y, Ding L, Russnes HG, Richardson AL, Babski K, Min Hui Kim E, ... ... Coussens LM, et al. Immune Escape in Breast Cancer During In Situ to Invasive Carcinoma Transition. Cancer Discovery. PMID 28652380 DOI: 10.1158/2159-8290.Cd-17-0222  0.371
2016 Palucka AK, Coussens LM. The Basis of Oncoimmunology. Cell. 164: 1233-47. PMID 26967289 DOI: 10.1016/J.Cell.2016.01.049  0.378
2016 Cuevas I, Layman H, Coussens L, Boudreau N. Correction: Sustained Endothelial Expression of HoxA5 In Vivo Impairs Pathological Angiogenesis And Tumor Progression. Plos One. 11: e0148833. PMID 26839951 DOI: 10.1371/Journal.Pone.0148833  0.389
2016 Ruhland MK, Coussens LM, Stewart SA. Senescence and cancer: An evolving inflammatory paradox. Biochimica Et Biophysica Acta. 1865: 14-22. PMID 26453912 DOI: 10.1016/J.Bbcan.2015.10.001  0.363
2016 Maller O, Cassereau L, Drain A, Ruffell B, Acerbi I, Broz M, Munson J, Swartz M, Krummel M, Coussens L, Weaver V. Abstract A098: A role for fibrosis in promoting pro-tumor immune response in breast cancer Cancer Immunology Research. 4. DOI: 10.1158/2326-6066.Imm2016-A098  0.565
2016 Wesolowski R, Sharma N, West B, Coussens L, Marimuthu A, Pelayo M, Le MH, Hsu H, Karlin DA, Rugo HS. A phase Ib study of pexidartinib (PLX3397) and weekly paclitaxel in patients with advanced solid tumors including an ovarian cancer subset Gynecologic Oncology. 141: 121. DOI: 10.1016/J.Ygyno.2016.04.325  0.413
2015 Gunderson AJ, Kaneda MM, Tsujikawa T, Nguyen AV, Affara NI, Ruffell B, Gorjestani S, Liudahl SM, Truitt M, Olson P, Kim G, Hanahan D, Tempero MA, Sheppard B, Irving B, ... ... Coussens LM, et al. Bruton's Tyrosine Kinase (BTK)-dependent immune cell crosstalk drives pancreas cancer. Cancer Discovery. PMID 26715645 DOI: 10.1158/2159-8290.Cd-15-0827  0.626
2015 Medler TR, Cotechini T, Coussens LM. Immune response to cancer therapy: mounting an effective antitumor response and mechanisms of resistance. Trends in Cancer. 1: 66-75. PMID 26457331 DOI: 10.1016/j.trecan.2015.07.008  0.376
2015 Cotechini T, Medler TR, Coussens LM. Myeloid Cells as Targets for Therapy in Solid Tumors. Cancer Journal (Sudbury, Mass.). 21: 343-50. PMID 26222088 DOI: 10.1097/PPO.0000000000000132  0.443
2015 Ruffell B, Coussens LM. Macrophages and therapeutic resistance in cancer. Cancer Cell. 27: 462-72. PMID 25858805 DOI: 10.1016/j.ccell.2015.02.015  0.388
2015 Cuevas I, Layman H, Coussens L, Boudreau N. Sustained endothelial expression of HoxA5 in vivo impairs pathological angiogenesis and tumor progression. Plos One. 10: e0121720. PMID 25821967 DOI: 10.1371/Journal.Pone.0121720  0.413
2015 Shiao SL, Ruffell B, DeNardo DG, Faddegon BA, Park CC, Coussens LM. TH2-Polarized CD4(+) T Cells and Macrophages Limit Efficacy of Radiotherapy. Cancer Immunology Research. 3: 518-25. PMID 25716473 DOI: 10.1158/2326-6066.CIR-14-0232  0.669
2015 Link JM, Allen-Petersen B, Gunderson A, Jorgens D, Dorrell C, Hooper J, Streeter P, Grompe M, Coussens L, Gray J, Hardaker H, Lopez CD, Sears RC, Sheppard BC. Abstract B118: Developing a molecular and cellular atlas of pancreatic disease Cancer Research. 75. DOI: 10.1158/1538-7445.Panca2014-B118  0.431
2014 Galluzzi L, Vacchelli E, Bravo-San Pedro JM, Buqué A, Senovilla L, Baracco EE, Bloy N, Castoldi F, Abastado JP, Agostinis P, Apte RN, Aranda F, Ayyoub M, Beckhove P, Blay JY, ... ... Coussens L, et al. Classification of current anticancer immunotherapies. Oncotarget. 5: 12472-508. PMID 25537519 DOI: 10.18632/Oncotarget.2998  0.423
2014 Fornetti J, Martinson HA, Betts CB, Lyons TR, Jindal S, Guo Q, Coussens LM, Borges VF, Schedin P. Mammary gland involution as an immunotherapeutic target for postpartum breast cancer. Journal of Mammary Gland Biology and Neoplasia. 19: 213-28. PMID 24952477 DOI: 10.1007/S10911-014-9322-Z  0.443
2014 Affara NI, Ruffell B, Medler TR, Gunderson AJ, Johansson M, Bornstein S, Bergsland E, Steinhoff M, Li Y, Gong Q, Ma Y, Wiesen JF, Wong MH, Kulesz-Martin M, Irving B, ... Coussens LM, et al. B cells regulate macrophage phenotype and response to chemotherapy in squamous carcinomas. Cancer Cell. 25: 809-21. PMID 24909985 DOI: 10.1016/J.Ccr.2014.04.026  0.348
2013 Strachan DC, Ruffell B, Oei Y, Bissell MJ, Coussens LM, Pryer N, Daniel D. CSF1R inhibition delays cervical and mammary tumor growth in murine models by attenuating the turnover of tumor-associated macrophages and enhancing infiltration by CD8(+) T cells. Oncoimmunology. 2: e26968. PMID 24498562 DOI: 10.4161/Onci.26968  0.444
2013 Palucka K, Coussens LM, O'Shaughnessy J. Dendritic cells, inflammation, and breast cancer. Cancer Journal (Sudbury, Mass.). 19: 511-6. PMID 24270350 DOI: 10.1097/PPO.0000000000000007  0.429
2013 Ruffell B, Affara NI, Cottone L, Junankar S, Johansson M, DeNardo DG, Korets L, Reinheckel T, Sloane BF, Bogyo M, Coussens LM. Cathepsin C is a tissue-specific regulator of squamous carcinogenesis. Genes & Development. 27: 2086-98. PMID 24065739 DOI: 10.1101/Gad.224899.113  0.662
2013 Ganesan AP, Johansson M, Ruffell B, Yagui-Beltrán A, Beltran A, Lau J, Jablons DM, Coussens LM. Tumor-infiltrating regulatory T cells inhibit endogenous cytotoxic T cell responses to lung adenocarcinoma. Journal of Immunology (Baltimore, Md. : 1950). 191: 2009-17. PMID 23851682 DOI: 10.4049/jimmunol.1301317  0.321
2013 Gunderson AJ, Coussens LM. B cells and their mediators as targets for therapy in solid tumors. Experimental Cell Research. 319: 1644-9. PMID 23499742 DOI: 10.1016/J.Yexcr.2013.03.005  0.406
2013 Coussens LM, Zitvogel L, Palucka AK. Neutralizing tumor-promoting chronic inflammation: a magic bullet? Science (New York, N.Y.). 339: 286-91. PMID 23329041 DOI: 10.1126/Science.1232227  0.417
2013 Keenan B, Saenger Y, Kafrouni M, Leubner A, Lauer P, Maitra A, Gunderson A, Coussens L, Armstrong T, Jaffee E. Abstract 489: Prevention of pancreatic intra-epithelial neoplasm progression by a Listeria monocytogenes vaccine targeting mutated Kras, an early genetic event in pancreatic tumor development. Cancer Research. 73: 489-489. DOI: 10.1158/1538-7445.Tumimm2012-Pr6  0.493
2013 Blakely C, Bose T, Wheeler M, Bueno R, Sugarbaker D, Jablons D, Broaddus VC, Coussens L. Abstract 4723: Macrophages foster neoplastic progression of malignant mesothelioma and limit response to chemotherapy. Cancer Research. 73: 4723-4723. DOI: 10.1158/1538-7445.Am2013-4723  0.414
2012 Daldrup-Link H, Coussens LM. MR imaging of tumor-associated macrophages. Oncoimmunology. 1: 507-509. PMID 22754769  0.359
2012 Coussens L. Q&A: Lisa Coussens on immune reprogramming. Cancer Discovery. 2: 478. PMID 22684441 DOI: 10.1158/2159-8290.Cd-Nd2012-025  0.366
2012 Hanahan D, Coussens LM. Accessories to the crime: functions of cells recruited to the tumor microenvironment. Cancer Cell. 21: 309-22. PMID 22439926 DOI: 10.1016/J.Ccr.2012.02.022  0.607
2012 Swartz MA, Iida N, Roberts EW, Sangaletti S, Wong MH, Yull FE, Coussens LM, DeClerck YA. Tumor microenvironment complexity: emerging roles in cancer therapy. Cancer Research. 72: 2473-80. PMID 22414581 DOI: 10.1158/0008-5472.Can-12-0122  0.437
2012 Ruffell B, Affara NI, Coussens LM. Differential macrophage programming in the tumor microenvironment. Trends in Immunology. 33: 119-26. PMID 22277903 DOI: 10.1016/j.it.2011.12.001  0.404
2012 Ruffell B, Au A, Rugo HS, Esserman LJ, Hwang ES, Coussens LM. Leukocyte composition of human breast cancer. Proceedings of the National Academy of Sciences of the United States of America. 109: 2796-801. PMID 21825174 DOI: 10.1073/pnas.1104303108  0.388
2011 Shiao SL, Ganesan AP, Rugo HS, Coussens LM. Immune microenvironments in solid tumors: new targets for therapy. Genes & Development. 25: 2559-72. PMID 22190457 DOI: 10.1101/gad.169029.111  0.41
2011 DeNardo DG, Brennan DJ, Rexhepaj E, Ruffell B, Shiao SL, Madden SF, Gallagher WM, Wadhwani N, Keil SD, Junaid SA, Rugo HS, Hwang ES, Jirström K, West BL, Coussens LM. Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy. Cancer Discovery. 1: 54-67. PMID 22039576 DOI: 10.1158/2159-8274.CD-10-0028  0.691
2011 Daldrup-Link HE, Golovko D, Ruffell B, Denardo DG, Castaneda R, Ansari C, Rao J, Tikhomirov GA, Wendland MF, Corot C, Coussens LM. MRI of tumor-associated macrophages with clinically applicable iron oxide nanoparticles. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 5695-704. PMID 21791632 DOI: 10.1158/1078-0432.Ccr-10-3420  0.599
2011 Erez N, Coussens LM. Leukocytes as paracrine regulators of metastasis and determinants of organ-specific colonization. International Journal of Cancer. 128: 2536-44. PMID 21387299 DOI: 10.1002/ijc.26032  0.388
2011 Masset A, Maillard C, Sounni NE, Jacobs N, Bruyére F, Delvenne P, Tacke M, Reinheckel T, Foidart JM, Coussens LM, Noël A. Unimpeded skin carcinogenesis in K14-HPV16 transgenic mice deficient for plasminogen activator inhibitor. International Journal of Cancer. 128: 283-93. PMID 20232379 DOI: 10.1002/ijc.25326  0.386
2011 Coussens L. PL2-1: Macrophages as Novel Targets for Therapy in Breast Cancer. Cancer Research. 71. DOI: 10.1158/0008-5472.Sabcs11-Pl2-1  0.513
2010 Shiao SL, Coussens LM. The tumor-immune microenvironment and response to radiation therapy. Journal of Mammary Gland Biology and Neoplasia. 15: 411-21. PMID 21161342 DOI: 10.1007/s10911-010-9194-9  0.41
2010 Ursini-Siegel J, Cory S, Zuo D, Hardy WR, Rexhepaj E, Lam S, Schade B, Jirstrom K, Bjur E, Piccirillo CA, Denardo D, Coussens LM, Brennan DJ, Gallagher WM, Park M, et al. Receptor tyrosine kinase signaling favors a protumorigenic state in breast cancer cells by inhibiting the adaptive immune response. Cancer Research. 70: 7776-87. PMID 20924104 DOI: 10.1158/0008-5472.Can-10-2229  0.711
2010 Doedens AL, Stockmann C, Rubinstein MP, Liao D, Zhang N, DeNardo DG, Coussens LM, Karin M, Goldrath AW, Johnson RS. Macrophage expression of hypoxia-inducible factor-1 alpha suppresses T-cell function and promotes tumor progression. Cancer Research. 70: 7465-75. PMID 20841473 DOI: 10.1158/0008-5472.Can-10-1439  0.74
2010 DeNardo DG, Andreu P, Coussens LM. Interactions between lymphocytes and myeloid cells regulate pro- versus anti-tumor immunity. Cancer Metastasis Reviews. 29: 309-16. PMID 20405169 DOI: 10.1007/s10555-010-9223-6  0.712
2010 Demaria S, Pikarsky E, Karin M, Coussens LM, Chen YC, El-Omar EM, Trinchieri G, Dubinett SM, Mao JT, Szabo E, Krieg A, Weiner GJ, Fox BA, Coukos G, Wang E, et al. Cancer and inflammation: promise for biologic therapy. Journal of Immunotherapy (Hagerstown, Md. : 1997). 33: 335-51. PMID 20386472 DOI: 10.1097/Cji.0B013E3181D32E74  0.341
2010 Sounni NE, Dehne K, van Kempen L, Egeblad M, Affara NI, Cuevas I, Wiesen J, Junankar S, Korets L, Lee J, Shen J, Morrison CJ, Overall CM, Krane SM, Werb Z, ... ... Coussens LM, et al. Stromal regulation of vessel stability by MMP14 and TGFbeta. Disease Models & Mechanisms. 3: 317-32. PMID 20223936 DOI: 10.1242/Dmm.003863  0.493
2010 Andreu P, Johansson M, Affara NI, Pucci F, Tan T, Junankar S, Korets L, Lam J, Tawfik D, DeNardo DG, Naldini L, de Visser KE, De Palma M, Coussens LM. FcRgamma activation regulates inflammation-associated squamous carcinogenesis. Cancer Cell. 17: 121-34. PMID 20138013 DOI: 10.1016/J.Ccr.2009.12.019  0.669
2010 Dennemärker J, Lohmüller T, Mayerle J, Tacke M, Lerch MM, Coussens LM, Peters C, Reinheckel T. Deficiency for the cysteine protease cathepsin L promotes tumor progression in mouse epidermis Oncogene. 29: 1611-1621. PMID 20023699 DOI: 10.1038/onc.2009.466  0.307
2010 Ruffell B, DeNardo DG, Affara NI, Coussens LM. Lymphocytes in cancer development: polarization towards pro-tumor immunity. Cytokine & Growth Factor Reviews. 21: 3-10. PMID 20005150 DOI: 10.1016/j.cytogfr.2009.11.002  0.711
2010 Okamoto J, Hirata T, Chen Z, Zhou H, Mikami I, Li H, Yagui-Beltran A, Johansson M, Coussens LM, Clement G, Shi Y, Zhang F, Koizumi K, Shimizu K, Jablons D, et al. Erratum: EMX2 is epigenetically silenced and suppresses growth in human lung cancer Oncogene. 29: 5976-5976. DOI: 10.1038/Onc.2010.450  0.301
2009 Sista AK, Knebel RJ, Tavri S, Johansson M, DeNardo DG, Boddington SE, Kishore SA, Ansari C, Reinhart V, Coakley FV, Coussens LM, Daldrup-Link HE. Optical imaging of the peri-tumoral inflammatory response in breast cancer. Journal of Translational Medicine. 7: 94. PMID 19906309 DOI: 10.1186/1479-5876-7-94  0.662
2009 DeNardo DG, Barreto JB, Andreu P, Vasquez L, Tawfik D, Kolhatkar N, Coussens LM. CD4(+) T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages. Cancer Cell. 16: 91-102. PMID 19647220 DOI: 10.1016/j.ccr.2009.06.018  0.69
2009 Affara NI, Andreu P, Coussens LM. Delineating protease functions during cancer development. Methods in Molecular Biology (Clifton, N.J.). 539: 1-32. PMID 19377975 DOI: 10.1007/978-1-60327-003-8_1  0.335
2008 DeNardo DG, Johansson M, Coussens LM. Inflaming gastrointestinal oncogenic programming. Cancer Cell. 14: 7-9. PMID 18598939 DOI: 10.1016/j.ccr.2008.06.010  0.621
2008 Johansson M, Denardo DG, Coussens LM. Polarized immune responses differentially regulate cancer development. Immunological Reviews. 222: 145-54. PMID 18363999 DOI: 10.1111/j.1600-065X.2008.00600.x  0.686
2008 Kenny HA, Kaur S, Coussens LM, Lengyel E. The initial steps of ovarian cancer cell metastasis are mediated by MMP-2 cleavage of vitronectin and fibronectin. The Journal of Clinical Investigation. 118: 1367-79. PMID 18340378 DOI: 10.1172/Jci33775  0.312
2008 DeNardo DG, Johansson M, Coussens LM. Immune cells as mediators of solid tumor metastasis. Cancer Metastasis Reviews. 27: 11-8. PMID 18066650 DOI: 10.1007/s10555-007-9100-0  0.71
2007 Kopitz C, Gerg M, Bandapalli OR, Ister D, Pennington CJ, Hauser S, Flechsig C, Krell HW, Antolovic D, Brew K, Nagase H, Stangl M, von Weyhern CW, Brücher BL, Brand K, ... Coussens LM, et al. Tissue inhibitor of metalloproteinases-1 promotes liver metastasis by induction of hepatocyte growth factor signaling. Cancer Research. 67: 8615-23. PMID 17875701 DOI: 10.1158/0008-5472.Can-07-0232  0.342
2007 DeNardo DG, Coussens LM. Inflammation and breast cancer. Balancing immune response: crosstalk between adaptive and innate immune cells during breast cancer progression. Breast Cancer Research : Bcr. 9: 212. PMID 17705880 DOI: 10.1186/bcr1746  0.683
2007 Egeblad M, Shen HC, Behonick DJ, Wilmes L, Eichten A, Korets LV, Kheradmand F, Werb Z, Coussens LM. Type I collagen is a genetic modifier of matrix metalloproteinase 2 in murine skeletal development. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 236: 1683-93. PMID 17440987 DOI: 10.1002/Dvdy.21159  0.413
2007 Affara NI, Coussens LM. IKKalpha at the crossroads of inflammation and metastasis. Cell. 129: 25-6. PMID 17418780 DOI: 10.1016/j.cell.2007.03.029  0.369
2007 Tan TT, Coussens LM. Humoral immunity, inflammation and cancer. Current Opinion in Immunology. 19: 209-16. PMID 17276050 DOI: 10.1016/j.coi.2007.01.001  0.399
2007 Johansson M, Tan T, de Visser KE, Coussens LM. Immune cells as anti-cancer therapeutic targets and tools. Journal of Cellular Biochemistry. 101: 918-26. PMID 17265430 DOI: 10.1002/jcb.21230  0.412
2006 Tlsty TD, Coussens LM. Tumor stroma and regulation of cancer development. Annual Review of Pathology. 1: 119-50. PMID 18039110 DOI: 10.1146/Annurev.Pathol.1.110304.100224  0.396
2006 de Visser KE, Coussens LM. The inflammatory tumor microenvironment and its impact on cancer development. Contributions to Microbiology. 13: 118-37. PMID 16627962 DOI: 10.1159/000092969  0.442
2006 van Kempen LC, de Visser KE, Coussens LM. Inflammation, proteases and cancer. European Journal of Cancer (Oxford, England : 1990). 42: 728-34. PMID 16524717 DOI: 10.1016/j.ejca.2006.01.004  0.319
2006 de Visser KE, Eichten A, Coussens LM. Paradoxical roles of the immune system during cancer development. Nature Reviews. Cancer. 6: 24-37. PMID 16397525 DOI: 10.1038/nrc1782  0.335
2005 Jodele S, Chantrain CF, Blavier L, Lutzko C, Crooks GM, Shimada H, Coussens LM, Declerck YA. The contribution of bone marrow-derived cells to the tumor vasculature in neuroblastoma is matrix metalloproteinase-9 dependent. Cancer Research. 65: 3200-8. PMID 15833851 DOI: 10.1158/0008-5472.Can-04-3770  0.339
2005 Robinson SC, Coussens LM. Soluble mediators of inflammation during tumor development. Advances in Cancer Research. 93: 159-87. PMID 15797447 DOI: 10.1016/S0065-230X(05)93005-4  0.308
2004 de Visser KE, Korets LV, Coussens LM. Early neoplastic progression is complement independent. Neoplasia (New York, N.Y.). 6: 768-76. PMID 15720803 DOI: 10.1593/neo.04250  0.309
2004 DeClerck YA, Mercurio AM, Stack MS, Chapman HA, Zutter MM, Muschel RJ, Raz A, Matrisian LM, Sloane BF, Noel A, Hendrix MJ, Coussens L, Padarathsingh M. Proteases, extracellular matrix, and cancer: a workshop of the path B study section. The American Journal of Pathology. 164: 1131-9. PMID 15039201 DOI: 10.1016/S0002-9440(10)63200-2  0.486
2004 Chantrain CF, Shimada H, Jodele S, Groshen S, Ye W, Shalinsky DR, Werb Z, Coussens LM, DeClerck YA. Stromal Matrix Metalloproteinase-9 Regulates the Vascular Architecture in Neuroblastoma by Promoting Pericyte Recruitment Cancer Research. 64: 1675-1686. PMID 14996727 DOI: 10.1158/0008-5472.Can-03-0160  0.558
2004 Rhee JS, Diaz R, Korets L, Hodgson JG, Coussens LM. TIMP-1 alters susceptibility to carcinogenesis. Cancer Research. 64: 952-61. PMID 14871825 DOI: 10.1158/0008-5472.CAN-03-2445  0.634
2003 van Kempen LC, Ruiter DJ, van Muijen GN, Coussens LM. The tumor microenvironment: a critical determinant of neoplastic evolution. European Journal of Cell Biology. 82: 539-48. PMID 14703010 DOI: 10.1078/0171-9335-00346  0.42
2003 Daniel D, Meyer-Morse N, Bergsland EK, Dehne K, Coussens LM, Hanahan D. Immune enhancement of skin carcinogenesis by CD4+ T cells. The Journal of Experimental Medicine. 197: 1017-28. PMID 12695493 DOI: 10.1084/Jem.20021047  0.543
2002 van Kempen LC, Rhee JS, Dehne K, Lee J, Edwards DR, Coussens LM. Epithelial carcinogenesis: dynamic interplay between neoplastic cells and their microenvironment. Differentiation; Research in Biological Diversity. 70: 610-23. PMID 12492502 DOI: 10.1046/J.1432-0436.2002.700914.X  0.628
2002 Coussens LM, Werb Z. Inflammation and cancer Nature. 420: 860-867. PMID 12490959 DOI: 10.1038/Nature01322  0.53
2002 van Kempen LC, Coussens LM. MMP9 potentiates pulmonary metastasis formation. Cancer Cell. 2: 251-2. PMID 12398887  0.377
2002 Rhee JS, Coussens LM. RECKing MMP function: implications for cancer development. Trends in Cell Biology. 12: 209-11. PMID 12062160 DOI: 10.1016/S0962-8924(02)02280-8  0.629
2001 Coussens LM, Werb Z. Inflammatory cells and cancer: think different! The Journal of Experimental Medicine. 193: F23-6. PMID 11257144 DOI: 10.1084/Jem.193.6.F23  0.558
2001 Coussens LM, Shapiro SD, Soloway PD, Werb Z. Models for gain-of-function and loss-of-function of MMPs. Transgenic and gene targeted mice. Methods in Molecular Biology (Clifton, N.J.). 151: 149-79. PMID 11217297 DOI: 10.1385/1-59259-046-2:149  0.405
2000 Coussens LM, Tinkle CL, Hanahan D, Werb Z. MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis. Cell. 103: 481-90. PMID 11081634 DOI: 10.1016/S0092-8674(00)00139-2  0.641
2000 McKerrow JH, Bhargava V, Hansell E, Huling S, Kuwahara T, Matley M, Coussens L, Warren R. A functional proteomics screen of proteases in colorectal carcinoma Molecular Medicine (Cambridge, Mass.). 6: 450-460. PMID 10952024 DOI: 10.1007/Bf03401787  0.442
2000 Bergers G, Coussens LM. Extrinsic regulators of epithelial tumor progression: metalloproteinases. Current Opinion in Genetics & Development. 10: 120-7. PMID 10679388 DOI: 10.1016/S0959-437X(99)00043-X  0.306
1999 Coussens LM, Raymond WW, Bergers G, Laig-Webster M, Behrendtsen O, Werb Z, Caughey GH, Hanahan D. Inflammatory mast cells up-regulate angiogenesis during squamous epithelial carcinogenesis. Genes & Development. 13: 1382-97. PMID 10364156 DOI: 10.1101/Gad.13.11.1382  0.681
1999 Werb Z, Vu TH, Rinkenberger JL, Coussens LM. Matrix-degrading proteases and angiogenesis during development and tumor formation. Apmis : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica. 107: 11-8. PMID 10190275 DOI: 10.1111/J.1699-0463.1999.Tb01521.X  0.535
1998 Bergers G, Hanahan D, Coussens LM. Angiogenesis and apoptosis are cellular parameters of neoplastic progression in transgenic mouse models of tumorigenesis. The International Journal of Developmental Biology. 42: 995-1002. PMID 9853830  0.577
1997 Coussens LM, Werb Z. Matrix metalloproteinases and the development of cancer. Chemistry & Biology. 3: 895-904. PMID 8939708 DOI: 10.1016/S1074-5521(96)90178-7  0.548
1986 Coussens L, Van Beveren C, Smith D, Chen E, Mitchell RL, Isacke CM, Verma IM, Ullrich A. Structural alteration of viral homologue of receptor proto-oncogene fms at carboxyl terminus Nature. 320: 277-280. PMID 2421165 DOI: 10.1038/320277A0  0.304
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