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Swati P. Deb - Publications

Affiliations: 
Wake Forest University School of Medicine, Winston-Salem, NC, United States 
Area:
Molecular Biology, Oncology
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43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Vaughan CA, Singh S, Subler MA, Windle JJ, Inoue K, Fry EA, Pillappa R, Grossman SR, Windle B, Andrew Yeudall W, Deb SP, Deb S. The oncogenicity of tumor-derived mutant p53 is enhanced by the recruitment of PLK3. Nature Communications. 12: 704. PMID 33514736 DOI: 10.1038/s41467-021-20928-8  0.506
2019 Singh S, Vaughan CA, Rabender C, Mikkelsen R, Deb S, Palit Deb S. DNA replication in progenitor cells and epithelial regeneration after lung injury requires the oncoprotein MDM2. Jci Insight. PMID 31527309 DOI: 10.1172/Jci.Insight.128194  0.368
2017 Vaughan CA, Singh S, Grossman SR, Windle B, P Deb S, Deb S. Gain-of-function p53 activates multiple signaling pathways to induce oncogenicity in lung cancer cells. Molecular Oncology. PMID 28423230 DOI: 10.1002/1878-0261.12068  0.495
2017 Singh S, Vaughan CA, Frum RA, Grossman SR, Deb S, Deb SP. Mutant p53 establishes targetable tumor dependency by promoting unscheduled replication. The Journal of Clinical Investigation. PMID 28394262 DOI: 10.1172/Jci87724  0.59
2016 Vaughan CA, Pearsall I, Singh S, Windle B, Deb SP, Grossman SR, Yeudall WA, Deb S. Addiction of lung cancer cells to GOF p53 is promoted by up-regulation of epidermal growth factor receptor through multiple contacts with p53 transactivation domain and promoter. Oncotarget. PMID 26820293 DOI: 10.18632/Oncotarget.6998  0.462
2014 Gadepalli VS, Deb SP, Deb S, Rao RR. Lung cancer stem cells, p53 mutations and MDM2. Sub-Cellular Biochemistry. 85: 359-70. PMID 25201204 DOI: 10.1007/978-94-017-9211-0_19  0.32
2014 Vaughan C, Pearsall I, Yeudall A, Deb SP, Deb S. p53: its mutations and their impact on transcription. Sub-Cellular Biochemistry. 85: 71-90. PMID 25201189 DOI: 10.1007/978-94-017-9211-0_4  0.543
2014 Vaughan CA, Deb SP, Deb S, Windle B. Preferred binding of gain-of-function mutant p53 to bidirectional promoters with coordinated binding of ETS1 and GABPA to multiple binding sites. Oncotarget. 5: 417-27. PMID 24481480 DOI: 10.18632/Oncotarget.1708  0.504
2014 Frum RA, Singh S, Vaughan C, Mukhopadhyay ND, Grossman SR, Windle B, Deb S, Deb SP. The human oncoprotein MDM2 induces replication stress eliciting early intra-S-phase checkpoint response and inhibition of DNA replication origin firing. Nucleic Acids Research. 42: 926-40. PMID 24163099 DOI: 10.1093/Nar/Gkt944  0.345
2013 Singh S, Ramamoorthy M, Vaughan C, Yeudall WA, Deb S, Palit Deb S. Human oncoprotein MDM2 activates the Akt signaling pathway through an interaction with the repressor element-1 silencing transcription factor conferring a survival advantage to cancer cells. Cell Death and Differentiation. 20: 558-66. PMID 23238568 DOI: 10.1038/cdd.2012.153  0.391
2013 Vaughan C, Deb SP, Deb S. Generation of p53 knock-down cell lines. Methods in Molecular Biology (Clifton, N.J.). 962: 193-9. PMID 23150448 DOI: 10.1007/978-1-62703-236-0_16  0.378
2012 Vaughan CA, Singh S, Windle B, Yeudall WA, Frum R, Grossman SR, Deb SP, Deb S. Gain-of-Function Activity of Mutant p53 in Lung Cancer through Up-Regulation of Receptor Protein Tyrosine Kinase Axl. Genes & Cancer. 3: 491-502. PMID 23264849 DOI: 10.1177/1947601912462719  0.554
2012 Vaughan CA, Frum R, Pearsall I, Singh S, Windle B, Yeudall A, Deb SP, Deb S. Allele specific gain-of-function activity of p53 mutants in lung cancer cells. Biochemical and Biophysical Research Communications. 428: 6-10. PMID 22989750 DOI: 10.1016/J.Bbrc.2012.09.029  0.567
2012 Vaughan CA, Singh S, Windle B, Sankala HM, Graves PR, Andrew Yeudall W, Deb SP, Deb S. p53 mutants induce transcription of NF-κB2 in H1299 cells through CBP and STAT binding on the NF-κB2 promoter and gain of function activity. Archives of Biochemistry and Biophysics. 518: 79-88. PMID 22198284 DOI: 10.1016/J.Abb.2011.12.006  0.515
2012 Yeudall WA, Vaughan CA, Miyazaki H, Ramamoorthy M, Choi MY, Chapman CG, Wang H, Black E, Bulysheva AA, Deb SP, Windle B, Deb S. Gain-of-function mutant p53 upregulates CXC chemokines and enhances cell migration. Carcinogenesis. 33: 442-51. PMID 22114072 DOI: 10.1093/Carcin/Bgr270  0.601
2011 Vaughan C, Mohanraj L, Singh S, Dumur CI, Ramamoorthy M, Garrett CT, Windle B, Yeudall WA, Deb S, Deb SP. Human Oncoprotein MDM2 Up-regulates Expression of NF-κB2 Precursor p100 Conferring a Survival Advantage to Lung Cells. Genes & Cancer. 2: 943-55. PMID 22701761 DOI: 10.1177/1947601911436008  0.451
2011 Graves P, Sankala H, Wang J, Vaughan C, Deb S. Upregulation of the Mitochondrial Transport Protein, Tim50, by Mutant P53 Contributes to Cell Growth and Chemoresistance International Journal of Radiation Oncology*Biology*Physics. 81: S55-S56. DOI: 10.1016/j.ijrobp.2011.06.112  0.325
2009 Frum R, Ramamoorthy M, Mohanraj L, Deb S, Deb SP. MDM2 controls the timely expression of cyclin A to regulate the cell cycle. Molecular Cancer Research : McR. 7: 1253-67. PMID 19671680 DOI: 10.1158/1541-7786.Mcr-08-0334  0.529
2008 Scian MJ, Carchman EH, Mohanraj L, Stagliano KE, Anderson MA, Deb D, Crane BM, Kiyono T, Windle B, Deb SP, Deb S. Wild-type p53 and p73 negatively regulate expression of proliferation related genes. Oncogene. 27: 2583-93. PMID 17982488 DOI: 10.1038/Sj.Onc.1210898  0.566
2007 Frum R, Busby SA, Ramamoorthy M, Deb S, Shabanowitz J, Hunt DF, Deb SP. HDM2-binding partners: interaction with translation elongation factor EF1alpha. Journal of Proteome Research. 6: 1410-7. PMID 17373842 DOI: 10.1021/Pr060584P  0.416
2005 Scian MJ, Stagliano KE, Anderson MA, Hassan S, Bowman M, Miles MF, Deb SP, Deb S. Tumor-derived p53 mutants induce NF-kappaB2 gene expression. Molecular and Cellular Biology. 25: 10097-110. PMID 16260623 DOI: 10.1128/Mcb.25.22.10097-10110.2005  0.569
2005 Zhou R, Frum R, Deb S, Deb SP. The growth arrest function of the human oncoprotein mouse double minute-2 is disabled by downstream mutation in cancer cells. Cancer Research. 65: 1839-48. PMID 15753382 DOI: 10.1158/0008-5472.Can-03-3755  0.406
2004 Scian MJ, Stagliano KER, Ellis MA, Hassan S, Bowman M, Miles MF, Deb SP, Deb S. Modulation of gene expression by tumor-derived p53 mutants Cancer Research. 64: 7447-7454. PMID 15492269 DOI: 10.1158/0008-5472.Can-04-1568  0.608
2004 Scian MJ, Stagliano KE, Deb D, Ellis MA, Carchman EH, Das A, Valerie K, Deb SP, Deb S. Tumor-derived p53 mutants induce oncogenesis by transactivating growth-promoting genes. Oncogene. 23: 4430-43. PMID 15077194 DOI: 10.1038/Sj.Onc.1207553  0.529
2003 Deb SP. Cell Cycle Regulatory Functions of the Human Oncoprotein MDM2 Molecular Cancer Research. 1: 1009-1016. PMID 14707284  0.373
2003 Scian MJ, Frum R, Deb SP, Deb S. Transactivation and transrepression studies with p53 Methods in Molecular Biology (Clifton, N.J.). 234: 93-110. PMID 12824527 DOI: 10.1385/1-59259-408-5:93  0.433
2002 Deb D, Scian M, Roth KE, Li W, Keiger J, Chakraborti AS, Deb SP, Deb S. Hetero-oligomerization does not compromise 'gain of function' of tumor-derived p53 mutants. Oncogene. 21: 176-89. PMID 11803461 DOI: 10.1038/sj.onc.1205035  0.586
2002 Deb SP. Function and dysfunction of the human oncoprotein MDM2 Frontiers in Bioscience : a Journal and Virtual Library. 7. PMID 11779693  0.375
2001 Brown DR, Deb D, Frum R, Hickes L, Munoz R, Deb S, Deb SP. The human oncoprotein MDM2 uses distinct strategies to inhibit transcriptional activation mediated by the wild-type p53 and its tumor-derived mutants. International Journal of Oncology. 18: 449-59. PMID 11179471 DOI: 10.3892/Ijo.18.3.449  0.691
2001 Deb D, Lanyi A, Scian M, Keiger J, Brown DR, Le Roith D, Deb SP, Deb S. Differential modulation of cellular and viral promoters by p73 and p53. International Journal of Oncology. 18: 401-9. PMID 11172610 DOI: 10.3892/Ijo.18.2.401  0.684
1998 Brown DR, Thomas CA, Deb SP. The human oncoprotein MDM2 arrests the cell cycle: elimination of its cell-cycle-inhibitory function induces tumorigenesis. The Embo Journal. 17: 2513-25. PMID 9564034 DOI: 10.1093/Emboj/17.9.2513  0.599
1996 Ludes-Meyers JH, Subler MA, Shivakumar CV, Munoz RM, Jiang P, Bigger JE, Brown DR, Deb SP, Deb S. Transcriptional activation of the human epidermal growth factor receptor promoter by human p53. Molecular and Cellular Biology. 16: 6009-19. PMID 8887630 DOI: 10.1128/Mcb.16.11.6009  0.698
1995 Shivakumar CV, Brown DR, Deb S, Deb SP. Wild-type human p53 transactivates the human proliferating cell nuclear antigen promoter Molecular and Cellular Biology. 15: 6785-6793. PMID 8524244 DOI: 10.1128/Mcb.15.12.6785  0.716
1995 Leng P, Brown DR, Shivakumar CV, Deb S, Deb SP. N-terminal 130 amino acids of MDM2 are sufficient to inhibit p53-mediated transcriptional activation. Oncogene. 10: 1275-82. PMID 7731677  0.626
1994 Martin DW, Muñoz RM, Oliver D, Subler MA, Deb S. Analysis of the DNA-binding domain of the HSV-1 origin-binding protein. Virology. 198: 71-80. PMID 8259684 DOI: 10.1006/Viro.1994.1009  0.415
1994 Deb SP, Muñoz RM, Brown DR, Subler MA, Deb S. Wild-type human p53 activates the human epidermal growth factor receptor promoter. Oncogene. 9: 1341-9. PMID 8152794  0.666
1994 Deb SP, Deb S, Brown DS. Cell-type-specific induction of the UL9 gene of HSV-1 by cell signaling pathway Biochemical and Biophysical Research Communications. 205: 44-51. PMID 7999061 DOI: 10.1006/bbrc.1994.2627  0.324
1993 Brown DR, Deb S, Muñoz RM, Subler MA, Deb SP. The tumor suppressor p53 and the oncoprotein simian virus 40 T antigen bind to overlapping domains on the MDM2 protein. Molecular and Cellular Biology. 13: 6849-57. PMID 8413278 DOI: 10.1128/Mcb.13.11.6849  0.693
1993 Martin DW, Subler MA, Muñoz RM, Brown DR, Deb SP, Deb S. p53 and SV40 T antigen bind to the same region overlapping the conserved domain of the TATA-binding protein. Biochemical and Biophysical Research Communications. 195: 428-34. PMID 8395834 DOI: 10.1006/bbrc.1993.2061  0.569
1993 Deb SP, Deb S, Brown DR. Analysis of the promoter sequences of the UL9 gene of herpes simplex virus type 1 Biochemical and Biophysical Research Communications. 193: 617-623. PMID 8390247 DOI: 10.1006/bbrc.1993.1669  0.493
1992 Deb S, Jackson CT, Subler MA, Martin DW. Modulation of cellular and viral promoters by mutant human p53 proteins found in tumor cells. Journal of Virology. 66: 6164-70. PMID 1356162 DOI: 10.1128/jvi.66.10.6164-6170.1992  0.601
1989 Deb S, Deb SP. Analysis of Ori-S sequence of HSV-1: Identification of one functional DNA binding domain Nucleic Acids Research. 17: 2733-2752. PMID 2541411 DOI: 10.1093/nar/17.7.2733  0.317
1989 Tack LC, Wright JH, Deb SP, Tegtmeyer P. The p53 complex from monkey cells modulates the biochemical activities of simian virus 40 large T antigen. Journal of Virology. 63: 1310-7. PMID 2521675 DOI: 10.1128/jvi.63.3.1310-1317.1989  0.368
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