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Dianne Little, Ph.D. - Publications

Affiliations: 
2006 North Carolina State University, Raleigh, NC 
Area:
Veterinary Science Biology, Animal Physiology Biology
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43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Little D, Amadio PC, Awad H, Cone SG, Dyment NA, Fisher MB, Huang AH, Koch DW, Kuntz AF, Madi R, McGilvrey K, Schnabel LV, Shetye SS, Thomopoulos S, Zhao C, et al. Preclinical Tendon and Ligament Models: Beyond the 3Rs (Replacement, Reduction, and Refinement) to 5W1H (Why, Who, What, Where, When, How). Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 37573480 DOI: 10.1002/jor.25678  0.527
2023 Jenkins TL, Sarmiento Huertas PA, Umemori K, Guilak F, Little D. Tendon-derived matrix crosslinking techniques for electrospun multi-layered scaffolds. Journal of Biomedical Materials Research. Part A. PMID 37489733 DOI: 10.1002/jbm.a.37588  0.471
2023 Xie S, Choudhari S, Wu CL, Abramson K, Corcoran D, Gregory SG, Thimmapuram J, Guilak F, Little D. Aging and obesity prime the methylome and transcriptome of adipose stem cells for disease and dysfunction. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 37: e22785. PMID 36794668 DOI: 10.1096/fj.202201413R  0.71
2021 Estes BT, Enomoto M, Moutos FT, Carson MA, Toth JM, Eggert P, Stallrich J, Willard VP, Veis DJ, Little D, Guilak F, Lascelles BDX. Biological resurfacing in a canine model of hip osteoarthritis. Science Advances. 7: eabi5918. PMID 34524840 DOI: 10.1126/sciadv.abi5918  0.736
2020 Kimmerling KA, Oswald SJ, Huebner JL, Little D, Kraus VB, Kang JX, Wu CL, Guilak F. Transgenic conversion of ω-6 to ω-3 polyunsaturated fatty acids via fat-1 reduces the severity of post-traumatic osteoarthritis. Arthritis Research & Therapy. 22: 83. PMID 32295649 DOI: 10.1186/S13075-020-02170-7  0.762
2020 Chainani A, Matson A, Chainani M, Marchand Colon AJ, Toth AP, Garrigues GE, Little D. Contracture and transient receptor potential channel upregulation in the anterior glenohumeral joint capsule of patients with end-stage osteoarthritis. Journal of Shoulder and Elbow Surgery. PMID 32113865 DOI: 10.1016/J.Jse.2019.11.013  0.305
2019 Jenkins TL, Little D. Synthetic scaffolds for musculoskeletal tissue engineering: cellular responses to fiber parameters. Npj Regenerative Medicine. 4: 15. PMID 31263573 DOI: 10.1038/S41536-019-0076-5  0.343
2019 Gilchrist CL, Leddy HA, Kaye L, Case ND, Rothenberg KE, Little D, Liedtke W, Hoffman BD, Guilak F. TRPV4-mediated calcium signaling in mesenchymal stem cells regulates aligned collagen matrix formation and vinculin tension. Proceedings of the National Academy of Sciences of the United States of America. PMID 30674675 DOI: 10.1073/Pnas.1811095116  0.756
2017 Jenkins T, Meehan S, Pourdeyhimi B, Little D. Meltblown Polymer Fabrics as Candidate Scaffolds for Rotator Cuff Tendon Tissue Engineering. Tissue Engineering. Part A. PMID 28816097 DOI: 10.1089/Ten.Tea.2016.0470  0.37
2017 Wu CL, McNeill J, Goon K, Little D, Kimmerling K, Huebner J, Kraus V, Guilak F. Conditional macrophage depletion increases inflammation and does not inhibit the development of osteoarthritis in obese MaFIA mice. Arthritis & Rheumatology (Hoboken, N.J.). PMID 28544542 DOI: 10.1002/Art.40161  0.764
2017 Wu CL, Kimmerling KA, Little D, Guilak F. Serum and synovial fluid lipidomic profiles predict obesity-associated osteoarthritis, synovitis, and wound repair. Scientific Reports. 7: 44315. PMID 28317846 DOI: 10.1038/Srep44315  0.772
2016 Little D, Johnson S, Hash J, Olson SA, Estes BT, Moutos FT, Lascelles BD, Guilak F. Functional outcome measures in a surgical model of hip osteoarthritis in dogs. Journal of Experimental Orthopaedics. 3: 17. PMID 27525982 DOI: 10.1186/S40634-016-0053-5  0.754
2016 O'Conor CJ, Ramalingam S, Zelenski NA, Benefield HC, Rigo I, Little D, Wu CL, Chen D, Liedtke W, McNulty AL, Guilak F. Cartilage-Specific Knockout of the Mechanosensory Ion Channel TRPV4 Decreases Age-Related Osteoarthritis. Scientific Reports. 6: 29053. PMID 27388701 DOI: 10.1038/Srep29053  0.776
2016 Chainani A, Little D. Current Status of Tissue-Engineered Scaffolds for Rotator Cuff Repair. Techniques in Orthopaedics (Rockville, Md.). 31: 91-97. PMID 27346922 DOI: 10.1097/Bto.0000000000000168  0.38
2016 Wu C, Kimmerling K, Little D, Guilak F. Serum free fatty acid levels as predictors of the severity of obesity-associated osteoarthritis Osteoarthritis and Cartilage. 24: S58-S59. DOI: 10.1016/J.Joca.2016.01.128  0.754
2015 Orr SB, Chainani A, Hippensteel KJ, Kishan A, Gilchrist C, Garrigues NW, Ruch DS, Guilak F, Little D. Aligned multilayered electrospun scaffolds for rotator cuff tendon tissue engineering. Acta Biomaterialia. 24: 117-26. PMID 26079676 DOI: 10.1016/J.Actbio.2015.06.010  0.778
2015 Lavagnino M, Wall ME, Little D, Banes AJ, Guilak F, Arnoczky SP. Tendon mechanobiology: Current knowledge and future research opportunities. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 33: 813-22. PMID 25763779 DOI: 10.1002/Jor.22871  0.492
2015 Wu C, McNeill J, Goon K, Little D, Kimmerling K, Huebner J, Kraus V, Guilak F. The effect of conditional macrophage depletion on development of injury-induced knee OA in obese transgenic MAFIA mice Osteoarthritis and Cartilage. 23: A286-A287. DOI: 10.1016/J.Joca.2015.02.522  0.73
2015 Orr SB, Chainani A, Hippensteel KJ, Kishan A, Gilchrist C, Garrigues NW, Ruch DS, Guilak F, Little D. Aligned multilayered electrospun scaffolds for rotator cuff tendon tissue engineering Acta Biomaterialia. DOI: 10.1016/j.actbio.2015.06.010  0.766
2014 Gilchrist CL, Ruch DS, Little D, Guilak F. Micro-scale and meso-scale architectural cues cooperate and compete to direct aligned tissue formation. Biomaterials. 35: 10015-24. PMID 25263687 DOI: 10.1016/J.Biomaterials.2014.08.047  0.762
2014 Wu CL, Jain D, McNeill JN, Little D, Anderson JA, Huebner JL, Kraus VB, Rodriguiz RM, Wetsel WC, Guilak F. Dietary fatty acid content regulates wound repair and the pathogenesis of osteoarthritis following joint injury. Annals of the Rheumatic Diseases. PMID 25015373 DOI: 10.1136/Annrheumdis-2014-205601  0.743
2014 Little D, Thompson JW, Dubois LG, Ruch DS, Moseley MA, Guilak F. Proteomic differences between male and female anterior cruciate ligament and patellar tendon. Plos One. 9: e96526. PMID 24818782 DOI: 10.1371/Journal.Pone.0096526  0.456
2014 Garrigues NW, Little D, Sanchez-Adams J, Ruch DS, Guilak F. Electrospun cartilage-derived matrix scaffolds for cartilage tissue engineering. Journal of Biomedical Materials Research. Part A. 102: 3998-4008. PMID 24375991 DOI: 10.1002/Jbm.A.35068  0.765
2014 Anderson JA, Little D, Toth AP, Moorman CT, Tucker BS, Ciccotti MG, Guilak F. Stem cell therapies for knee cartilage repair: the current status of preclinical and clinical studies. The American Journal of Sports Medicine. 42: 2253-61. PMID 24220016 DOI: 10.1177/0363546513508744  0.502
2013 Chainani A, Hippensteel KJ, Kishan A, Garrigues NW, Ruch DS, Guilak F, Little D. Multilayered electrospun scaffolds for tendon tissue engineering. Tissue Engineering. Part A. 19: 2594-604. PMID 23808760 DOI: 10.1089/Ten.Tea.2013.0165  0.795
2013 Wu C, Jain D, Little D, Anderson J, Huebner J, Kraus V, Rodriguiz R, Wetsel W, Guilak F. Dietary fatty acids differentially affect the development of injury-induced osteoarthritis with diet-induced obesity in mice Osteoarthritis and Cartilage. 21: S224-S225. DOI: 10.1016/J.Joca.2013.02.464  0.728
2012 Rowland CR, Little D, Guilak F. Factors influencing the long-term behavior of extracellular matrix-derived scaffolds for musculoskeletal soft tissue repair. Journal of Long-Term Effects of Medical Implants. 22: 181-93. PMID 23582110 DOI: 10.1615/Jlongtermeffmedimplants.2013006120  0.796
2011 Lewis JS, Hembree WC, Furman BD, Tippets L, Cattel D, Huebner JL, Little D, DeFrate LE, Kraus VB, Guilak F, Olson SA. Acute joint pathology and synovial inflammation is associated with increased intra-articular fracture severity in the mouse knee. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 19: 864-73. PMID 21619936 DOI: 10.1016/J.Joca.2011.04.011  0.455
2010 Garrigues NW, Little D, O'Conor CJ, Guilak F. Use of an insulating mask for controlling anisotropy in multilayer electrospun scaffolds for tissue engineering. Journal of Materials Chemistry. 20: 8962-8968. PMID 21072247 DOI: 10.1039/C0Jm01880E  0.754
2010 Little D, Guilak F, Ruch DS. Ligament-derived matrix stimulates a ligamentous phenotype in human adipose-derived stem cells. Tissue Engineering. Part A. 16: 2307-19. PMID 20406104 DOI: 10.1089/Ten.Tea.2009.0720  0.522
2008 Fogle CA, Gerard MP, Elce YA, Little D, Morton AJ, Correa MT, Blikslager AT. Analysis of sodium carboxymethylcellulose administration and related factors associated with postoperative colic and survival in horses with small intestinal disease. Veterinary Surgery : Vs. 37: 558-63. PMID 19134106 DOI: 10.1111/J.1532-950X.2008.00420.X  0.498
2007 Little D, Jones SL, Blikslager AT. Cyclooxygenase (COX) inhibitors and the intestine. Journal of Veterinary Internal Medicine / American College of Veterinary Internal Medicine. 21: 367-77. PMID 17552439 DOI: 10.1111/J.1939-1676.2007.Tb02978.X  0.516
2007 Little D, Brown SA, Campbell NB, Moeser AJ, Davis JL, Blikslager AT. Effects of the cyclooxygenase inhibitor meloxicam on recovery of ischemia-injured equine jejunum. American Journal of Veterinary Research. 68: 614-24. PMID 17542694 DOI: 10.2460/Ajvr.68.6.614  0.753
2007 Moeser AJ, Klok CV, Ryan KA, Wooten JG, Little D, Cook VL, Blikslager AT. Stress signaling pathways activated by weaning mediate intestinal dysfunction in the pig. American Journal of Physiology. Gastrointestinal and Liver Physiology. 292: G173-81. PMID 16901995 DOI: 10.1152/Ajpgi.00197.2006  0.744
2006 Davis JL, Little D, Blikslager AT, Papich MG. Mucosal permeability of water-soluble drugs in the equine jejunum: a preliminary investigation. Journal of Veterinary Pharmacology and Therapeutics. 29: 379-85. PMID 16958782 DOI: 10.1111/J.1365-2885.2006.00757.X  0.519
2005 Little D, Tomlinson JE, Blikslager AT. Post operative neutrophilic inflammation in equine small intestine after manipulation and ischaemia. Equine Veterinary Journal. 37: 329-35. PMID 16028622 DOI: 10.2746/0425164054529472  0.741
2005 Tschetter JR, Blikslager AT, Little D, Howard RD, Woody SL, Beex LM, Crisman MV. Detection of differentially regulated genes in ischaemic equine intestinal mucosa. Equine Veterinary Journal. 37: 319-24. PMID 16028620 DOI: 10.2746/0425164054529382  0.526
2005 Little D, White CE, Young KM, Blikslager AT. Faecal bile loss in horses following small intestinal resection. Equine Veterinary Journal. 37: 92-4. PMID 15651742 DOI: 10.2746/0425164054406883  0.504
2004 Moeser AJ, Haskell MM, Shifflett DE, Little D, Schultz BD, Blikslager AT. ClC-2 chloride secretion mediates prostaglandin-induced recovery of barrier function in ischemia-injured porcine ileum. Gastroenterology. 127: 802-15. PMID 15362036 DOI: 10.1053/J.Gastro.2004.06.004  0.746
2003 Little D, Dean RA, Young KM, McKane SA, Martin LD, Jones SL, Blikslager AT. PI3K signaling is required for prostaglandin-induced mucosal recovery in ischemia-injured porcine ileum. American Journal of Physiology. Gastrointestinal and Liver Physiology. 284: G46-56. PMID 12388204 DOI: 10.1152/Ajpgi.00121.2002  0.528
2002 Little D, Blikslager AT. Factors associated with development of ileal impaction in horses with surgical colic: 78 cases (1986-2000). Equine Veterinary Journal. 34: 464-8. PMID 12358048 DOI: 10.2746/042516402776117773  0.497
2002 Blikslager AT, Zimmel DN, Young KM, Campbell NB, Little D, Argenzio RA. Recovery of ischaemic injured porcine ileum: evidence for a contributory role of COX-1 and COX-2. Gut. 50: 615-23. PMID 11950805 DOI: 10.1136/Gut.50.5.615  0.758
2001 Little D, Redding WR, Blikslager AT. Risk factors for reduced postoperative fecal output in horses: 37 cases (1997-1998). Journal of the American Veterinary Medical Association. 218: 414-20. PMID 11201570  0.438
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