| Year |
Citation |
Score |
| 2024 |
Rebolledo EMD, Chan D, Christensen KE, Reagan AM, Howell GR, Rozen R, Trasler J. Sperm DNA methylation defects in a new mouse model of the 5,10-methylenetetrahydrofolate reductase 677C>T variant and correction with moderate dose folic acid supplementation. Molecular Human Reproduction. PMID 38366926 DOI: 10.1093/molehr/gaae008 |
0.717 |
|
| 2024 |
Lismer A, Shao X, Dumargne MC, Lafleur C, Lambrot R, Chan D, Toft G, Bonde JP, MacFarlane AJ, Bornman R, Aneck-Hahn N, Patrick S, Bailey JM, de Jager C, Dumeaux V, et al. The Association between Long-Term DDT or DDE Exposures and an Altered Sperm Epigenome-a Cross-Sectional Study of Greenlandic Inuit and South African VhaVenda Men. Environmental Health Perspectives. 132: 17008. PMID 38294233 DOI: 10.1289/EHP12013 |
0.528 |
|
| 2023 |
Karahan G, Martel J, Rahimi S, Farag M, Matias F, MacFarlane AJ, Chan D, Trasler J. Higher incidence of embryonic defects in mouse offspring conceived with assisted reproduction from fathers with sperm Epimutations. Human Molecular Genetics. PMID 37740387 DOI: 10.1093/hmg/ddad160 |
0.716 |
|
| 2023 |
Rahimi S, Shao X, Chan D, Martel J, Bérard A, Fraser WD, Simon MM, Kwan T, Bourque G, Trasler J. Capturing sex-specific and hypofertility-linked effects of assisted reproductive technologies on the cord blood DNA methylome. Clinical Epigenetics. 15: 82. PMID 37170172 DOI: 10.1186/s13148-023-01497-7 |
0.695 |
|
| 2023 |
Chan D, Ly L, Rebolledo EMD, Martel J, Landry M, Scott-Boyer MP, Droit A, Trasler JM. Transgenerational impact of grand-paternal lifetime exposures to both folic acid deficiency and supplementation on genome-wide DNA methylation in male germ cells. Andrology. PMID 36697378 DOI: 10.1111/andr.13399 |
0.733 |
|
| 2023 |
Chan D, Oros Klein K, Riera-Escamilla A, Krausz C, O'Flaherty C, Chan P, Robaire B, Trasler JM. Sperm DNA methylome abnormalities occur both pre- and post-treatment in men with Hodgkin disease and testicular cancer. Clinical Epigenetics. 15: 5. PMID 36611168 DOI: 10.1186/s13148-022-01417-1 |
0.645 |
|
| 2021 |
Maurice C, Dalvai M, Lambrot R, Deschênes A, Scott-Boyer MP, McGraw S, Chan D, Côté N, Ziv-Gal A, Flaws JA, Droit A, Trasler J, Kimmins S, Bailey JL. Early-Life Exposure to Environmental Contaminants Perturbs the Sperm Epigenome and Induces Negative Pregnancy Outcomes for Three Generations via the Paternal Lineage. Epigenomes. 5. PMID 34968297 DOI: 10.3390/epigenomes5020010 |
0.761 |
|
| 2021 |
Lambrot R, Chan D, Shao X, Aarabi M, Kwan T, Bourque G, Moskovtsev S, Librach C, Trasler J, Dumeaux V, Kimmins S. Whole-genome sequencing of H3K4me3 and DNA methylation in human sperm reveals regions of overlap linked to fertility and development. Cell Reports. 36: 109418. PMID 34289352 DOI: 10.1016/j.celrep.2021.109418 |
0.723 |
|
| 2021 |
Karahan G, Chan D, Shirane K, McClatchie T, Janssen S, Baltz JM, Lorincz M, Trasler J. Paternal MTHFR deficiency leads to hypomethylation of young retrotransposons and reproductive decline across two successive generations. Development (Cambridge, England). PMID 34128976 DOI: 10.1242/dev.199492 |
0.687 |
|
| 2020 |
Ly L, Chan D, Landry M, Angle C, Martel J, Trasler J. Impact of mothers' early life exposure to low or high folate on progeny outcome and DNA methylation patterns. Environmental Epigenetics. 6: dvaa018. PMID 33240529 DOI: 10.1093/eep/dvaa018 |
0.667 |
|
| 2020 |
Legault LM, Doiron K, Lemieux A, Caron M, Chan D, Lopes FL, Bourque G, Sinnett D, McGraw S. Developmental genome-wide DNA methylation asymmetry between mouse placenta and embryo. Epigenetics. 1-16. PMID 32056496 DOI: 10.1080/15592294.2020.1722922 |
0.612 |
|
| 2019 |
Legault LM, Chan D, McGraw S. Rapid Multiplexed Reduced Representation Bisulfite Sequencing Library Prep (rRRBS). Bio-Protocol. 9: e3171. PMID 33654977 DOI: 10.21769/BioProtoc.3171 |
0.714 |
|
| 2019 |
Chan D, Shao X, Dumargne MC, Aarabi M, Simon MM, Kwan T, Bailey JL, Robaire B, Kimmins S, San Gabriel MC, Zini A, Librach C, Moskovtsev S, Grundberg E, Bourque G, et al. Customized MethylC-Capture Sequencing to Evaluate Variation in the Human Sperm DNA Methylome Representative of Altered Folate Metabolism. Environmental Health Perspectives. 127: 87002. PMID 31393794 DOI: 10.1289/Ehp4812 |
0.752 |
|
| 2019 |
Rahimi S, Martel J, Karahan G, Angle C, Behan NA, Chan D, MacFarlane AJ, Trasler JM. Moderate maternal folic acid supplementation ameliorates adverse embryonic and epigenetic outcomes associated with assisted reproduction in a mouse model. Human Reproduction (Oxford, England). PMID 30989206 DOI: 10.1093/Humrep/Dez036 |
0.613 |
|
| 2018 |
Aarabi M, Christensen KE, Chan D, Leclerc D, Landry M, Ly L, Rozen R, Trasler J. Testicular MTHFR deficiency may explain sperm DNA hypomethylation associated with high dose folic acid supplementation. Human Molecular Genetics. PMID 29360980 DOI: 10.1093/Hmg/Ddy021 |
0.707 |
|
| 2017 |
Ly L, Chan D, Aarabi M, Landry M, Behan NA, MacFarlane AJ, Trasler J. Intergenerational impact of paternal lifetime exposures to both folic acid deficiency and supplementation on reproductive outcomes and imprinted gene methylation. Molecular Human Reproduction. PMID 28535307 DOI: 10.1093/Molehr/Gax029 |
0.64 |
|
| 2016 |
Whidden L, Martel J, Rahimi S, Chaillet JR, Chan D, Trasler JM. Compromised oocyte quality and assisted reproduction contribute to sex-specific effects on offspring outcomes and epigenetic patterning. Human Molecular Genetics. 25: 4649-4660. PMID 28173052 DOI: 10.1093/Hmg/Ddw293 |
0.764 |
|
| 2016 |
Chan D, McGraw S, Klein K, Wallock LM, Konermann C, Plass C, Chan P, Robaire B, Jacob RA, Greenwood CM, Trasler JM. Stability of the human sperm DNA methylome to folic acid fortification and short-term supplementation. Human Reproduction (Oxford, England). PMID 27994001 DOI: 10.1093/Humrep/Dew308 |
0.659 |
|
| 2016 |
Whidden L, Martel J, Rahimi S, Richard Chaillet J, Chan D, Trasler JM. Compromised oocyte quality and assisted reproduction contribute to sex-specific effects on offspring outcomes and epigenetic patterning. Human Molecular Genetics. PMID 27571894 DOI: 10.1093/hmg/ddw293 |
0.745 |
|
| 2015 |
Aarabi M, San Gabriel MC, Chan D, Behan NA, Caron M, Pastinen T, Bourque G, MacFarlane AJ, Zini A, Trasler J. High-dose folic acid supplementation alters the human sperm methylome and is influenced by the MTHFR C677T polymorphism. Human Molecular Genetics. 24: 6301-13. PMID 26307085 DOI: 10.1093/Hmg/Ddv338 |
0.726 |
|
| 2015 |
Ly L, Chan D, Trasler JM. Developmental windows of susceptibility for epigenetic inheritance through the male germline. Seminars in Cell & Developmental Biology. 43: 96-105. PMID 26265561 DOI: 10.1016/J.Semcdb.2015.07.006 |
0.71 |
|
| 2015 |
McGraw S, Zhang JX, Farag M, Chan D, Caron M, Konermann C, Oakes CC, Mohan KN, Plass C, Pastinen T, Bourque G, Chaillet JR, Trasler JM. Transient DNMT1 suppression reveals hidden heritable marks in the genome. Nucleic Acids Research. 43: 1485-97. PMID 25578964 DOI: 10.1093/Nar/Gku1386 |
0.812 |
|
| 2015 |
Shaffer B, McGraw S, Xiao SC, Chan D, Trasler J, Chaillet JR. The DNMT1 intrinsically disordered domain regulates genomic methylation during development. Genetics. 199: 533-41. PMID 25533200 DOI: 10.1534/Genetics.114.173609 |
0.809 |
|
| 2013 |
Delbès G, Chan D, Hales BF, Trasler JM, Robaire B. Selective induction of glutathione S-transferases in round spermatids from the Brown-Norway rat by the chemotherapeutic regimen for testicular cancer. Reproductive Toxicology (Elmsford, N.Y.). 36: 24-32. PMID 23200778 DOI: 10.1016/J.Reprotox.2012.10.012 |
0.641 |
|
| 2013 |
Niles KM, Yeh JR, Chan D, Landry M, Nagano MC, Trasler JM. Haploinsufficiency of the paternal-effect gene Dnmt3L results in transient DNA hypomethylation in progenitor cells of the male germline. Human Reproduction (Oxford, England). 28: 519-30. PMID 23159436 DOI: 10.1093/Humrep/Des395 |
0.796 |
|
| 2012 |
Saferali A, Moussette S, Chan D, Trasler J, Chen T, Rozen R, Naumova AK. DNA methyltransferase 1 (Dnmt1) mutation affects Snrpn imprinting in the mouse male germ line. Genome / National Research Council Canada = GéNome / Conseil National De Recherches Canada. 55: 673-82. PMID 22967183 DOI: 10.1139/G2012-056 |
0.741 |
|
| 2012 |
Chan D, Delbès G, Landry M, Robaire B, Trasler JM. Epigenetic alterations in sperm DNA associated with testicular cancer treatment. Toxicological Sciences : An Official Journal of the Society of Toxicology. 125: 532-43. PMID 22076425 DOI: 10.1093/Toxsci/Kfr307 |
0.721 |
|
| 2011 |
Niles KM, Chan D, La Salle S, Oakes CC, Trasler JM. Critical period of nonpromoter DNA methylation acquisition during prenatal male germ cell development. Plos One. 6: e24156. PMID 21949694 DOI: 10.1371/Journal.Pone.0024156 |
0.823 |
|
| 2010 |
Chan D, Cushnie DW, Neaga OR, Lawrance AK, Rozen R, Trasler JM. Strain-specific defects in testicular development and sperm epigenetic patterns in 5,10-methylenetetrahydrofolate reductase-deficient mice. Endocrinology. 151: 3363-73. PMID 20444942 DOI: 10.1210/En.2009-1340 |
0.655 |
|
| 2010 |
Landry M, Chan D, Martel J, Rozen R, Trasler J. Folate Deficiency and Supplementation Result in DNA Methylation Defects in Sperm. Biology of Reproduction. 83: 308-308. DOI: 10.1093/Biolreprod/83.S1.308 |
0.73 |
|
| 2009 |
Lopes FL, Fortier AL, Darricarrère N, Chan D, Arnold DR, Trasler JM. Reproductive and epigenetic outcomes associated with aging mouse oocytes. Human Molecular Genetics. 18: 2032-44. PMID 19293340 DOI: 10.1093/Hmg/Ddp127 |
0.712 |
|
| 2009 |
Delbès G, Chan D, Pakarinen P, Trasler JM, Hales BF, Robaire B. Impact of the chemotherapy cocktail used to treat testicular cancer on the gene expression profile of germ cells from male Brown-Norway rats. Biology of Reproduction. 80: 320-7. PMID 18987330 DOI: 10.1095/Biolreprod.108.072108 |
0.609 |
|
| 2008 |
Delbes G, Chan D, Hales B, Trasler J, Robaire B. Selective Induction of Glutathione S-transferases in Round Spematids by the Chemotherapeutic Regimen for Testicular Cancer in the Brown-Norway Rat. Biology of Reproduction. 78: 228-228. DOI: 10.1093/Biolreprod/78.S1.228 |
0.521 |
|
| 2008 |
Chan D, Delbes G, Smiraglia D, Robaire B, Trasler J. Identification of Brown Norway Rat Genomic Loci Altered in Germ Cell Methylation Patterns Due to Combination Chemotherapy for Testicular Cancer. Biology of Reproduction. 78: 193-193. DOI: 10.1093/Biolreprod/78.S1.193B |
0.646 |
|
| 2007 |
Cushnie D, Chan D, Neaga O, Lawrence A, Rima R, Trasler J. MTHFR-DEFICIENT MICE AS A MODEL FOR EPIGENETIC DISTURBANCE OF SPERMATOGENESIS THROUGH FOLATE PATHWAY DISRUPTION Biology of Reproduction. 77: 149-149. DOI: 10.1093/Biolreprod/77.S1.149A |
0.586 |
|
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