Yin-Shan Ng, Ph.D. - Publications

Affiliations: 
2000 Harvard University, Cambridge, MA, United States 
Area:
Cell Biology, Molecular Biology, Genetics

36 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Park-Windhol C, Ng YS, Yang J, Primo V, Saint-Geniez M, D'Amore PA. Author Correction: Endomucin knockdown inhibits VEGF-induced endothelial cell migration, growth, and morphogenesis by modulating VEGFR2 signaling. Scientific Reports. 13: 16620. PMID 37789044 DOI: 10.1038/s41598-023-43612-x  0.715
2021 Gnanaguru G, Mackey A, Choi EY, Arta A, Rossato FA, Gero TW, Urquhart AJ, Scott DA, D'Amore PA, Ng YSE. Discovery of sterically-hindered phenol compounds with potent cytoprotective activities against ox-LDL-induced retinal pigment epithelial cell death as a potential pharmacotherapy. Free Radical Biology & Medicine. PMID 34843917 DOI: 10.1016/j.freeradbiomed.2021.11.026  0.483
2021 Shen J, Rossato FA, Cano I, Ng YSE. Novel engineered, membrane-tethered VEGF-A variants promote formation of filopodia, proliferation, survival, and cord or tube formation by endothelial cells via persistent VEGFR2/ERK signaling and activation of CDC42/ROCK pathways. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 35: e22036. PMID 34793603 DOI: 10.1096/fj.202100448RR  0.637
2021 Cano I, Hu Z, AbuSamra DB, Saint-Geniez M, Ng YSE, Argüeso P, D'Amore PA. Galectin-3 Enhances Vascular Endothelial Growth Factor-A Receptor 2 Activity in the Presence of Vascular Endothelial Growth Factor. Frontiers in Cell and Developmental Biology. 9: 734346. PMID 34616740 DOI: 10.3389/fcell.2021.734346  0.769
2020 Rossato FA, Su Y, Mackey A, Ng YSE. Fibrotic Changes and Endothelial-to-Mesenchymal Transition Promoted by VEGFR2 Antagonism Alter the Therapeutic Effects of VEGFA Pathway Blockage in a Mouse Model of Choroidal Neovascularization. Cells. 9. PMID 32917003 DOI: 10.3390/cells9092057  0.555
2020 Hu Z, Cano I, Saez-Torres KL, LeBlanc ME, Saint-Geniez M, Ng YS, Argüeso P, D'Amore PA. Elements of the Endomucin Extracellular Domain Essential for VEGF-Induced VEGFR2 Activity. Cells. 9. PMID 32517158 DOI: 10.3390/Cells9061413  0.76
2020 Yang J, LeBlanc ME, Cano I, Saez-Torres KL, Saint-Geniez M, Ng YS, D'Amore PA. ADAM10 and ADAM17 proteases mediate proinflammatory cytokine-induced and constitutive cleavage of endomucin from the endothelial surface. The Journal of Biological Chemistry. PMID 32193206 DOI: 10.1074/Jbc.Ra119.011192  0.604
2019 LeBlanc ME, Saez-Torres KL, Cano I, Hu Z, Saint-Geniez M, Ng YS, D'Amore PA. Glycocalyx regulation of vascular endothelial growth factor receptor 2 activity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201900011R. PMID 31141406 DOI: 10.1096/Fj.201900011R  0.758
2018 Shen J, Xiao R, Bair J, Wang F, Vandenberghe LH, Dartt D, Baranov P, Ng YSE. Novel engineered, membrane-localized variants of vascular endothelial growth factor (VEGF) protect retinal ganglion cells: a proof-of-concept study. Cell Death & Disease. 9: 1018. PMID 30282966 DOI: 10.1038/S41419-018-1049-0  0.602
2017 Park-Windhol C, Ng YS, Yang J, Primo V, Saint-Geniez M, D'Amore PA. Endomucin inhibits VEGF-induced endothelial cell migration, growth, and morphogenesis by modulating VEGFR2 signaling. Scientific Reports. 7: 17138. PMID 29215001 DOI: 10.1038/s41598-017-16852-x  0.739
2016 Paneghetti L, Ng YS. A novel endothelial-derived anti-inflammatory activity significantly inhibits spontaneous choroidal neovascularisation in a mouse model. Vascular Cell. 8: 2. PMID 27175278 DOI: 10.1186/s13221-016-0036-4  0.431
2015 Nagai N, Ju M, Izumi-Nagai K, Robbie SJ, Bainbridge JW, Gale DC, Pierre E, Krauss AH, Adamson P, Shima DT, Ng YS. Novel CCR3 Antagonists Are Effective Mono- and Combination Inhibitors of Choroidal Neovascular Growth and Vascular Permeability. The American Journal of Pathology. 185: 2534-49. PMID 26188133 DOI: 10.1016/j.ajpath.2015.04.029  0.451
2015 Park-Windhol C, Yang J, Primo V, Ng Y, Saint-Geniez M, D'Amore P. Endomucin Plays a Role in Retinal Vascular Development and in VEGF-Induced Endothelial Cell Migration, Growth, and Morphogenesis The Faseb Journal. 29. DOI: 10.1096/Fasebj.29.1_Supplement.418.1  0.764
2014 Nagai N, Lundh von Leithner P, Izumi-Nagai K, Hosking B, Chang B, Hurd R, Adamson P, Adamis AP, Foxton RH, Ng YS, Shima DT. Spontaneous CNV in a novel mutant mouse is associated with early VEGF-A-driven angiogenesis and late-stage focal edema, neural cell loss, and dysfunction. Investigative Ophthalmology & Visual Science. 55: 3709-19. PMID 24845632 DOI: 10.1167/iovs.14-13989  0.421
2013 Foxton RH, Finkelstein A, Vijay S, Dahlmann-Noor A, Khaw PT, Morgan JE, Shima DT, Ng YS. VEGF-A is necessary and sufficient for retinal neuroprotection in models of experimental glaucoma. The American Journal of Pathology. 182: 1379-90. PMID 23416159 DOI: 10.1016/J.Ajpath.2012.12.032  0.632
2013 Robbie SJ, Lundh von Leithner P, Ju M, Lange CA, King AG, Adamson P, Lee D, Sychterz C, Coffey P, Ng YS, Bainbridge JW, Shima DT. Assessing a novel depot delivery strategy for noninvasive administration of VEGF/PDGF RTK inhibitors for ocular neovascular disease. Investigative Ophthalmology & Visual Science. 54: 1490-500. PMID 23385800 DOI: 10.1167/Iovs.12-10169  0.342
2009 Krilleke D, Ng YS, Shima DT. The heparin-binding domain confers diverse functions of VEGF-A in development and disease: a structure-function study. Biochemical Society Transactions. 37: 1201-6. PMID 19909247 DOI: 10.1042/BST0371201  0.565
2008 Mitchell TS, Bradley J, Robinson GS, Shima DT, Ng YS. RGS5 expression is a quantitative measure of pericyte coverage of blood vessels Angiogenesis. 11: 141-151. PMID 18038251 DOI: 10.1007/S10456-007-9085-X  0.652
2007 Krilleke D, DeErkenez A, Schubert W, Giri I, Robinson GS, Ng YS, Shima DT. Molecular mapping and functional characterization of the VEGF164 heparin-binding domain Journal of Biological Chemistry. 282: 28045-28056. PMID 17626017 DOI: 10.1074/Jbc.M700319200  0.567
2007 Nishijima K, Ng YS, Zhong L, Bradley J, Schubert W, Jo N, Akita J, Samuelsson SJ, Robinson GS, Adamis AP, Shima DT. Vascular endothelial growth factor-A is a survival factor for retinal neurons and a critical neuroprotectant during the adaptive response to ischemic injury American Journal of Pathology. 171: 53-67. PMID 17591953 DOI: 10.2353/Ajpath.2007.061237  0.638
2007 Zhong L, Bradley J, Schubert W, Ahmed E, Adamis AP, Shima DT, Robinson GS, Ng YS. Erythropoietin promotes survival of retinal ganglion cells in DBA/2J glaucoma mice Investigative Ophthalmology and Visual Science. 48: 1212-1218. PMID 17325165 DOI: 10.1167/Iovs.06-0757  0.304
2006 Ioannidou S, Deinhardt K, Miotla J, Bradley J, Cheung E, Samuelsson S, Ng YS, Shima DT. An in vitro assay reveals a role for the diaphragm protein PV-1 in endothelial fenestra morphogenesis. Proceedings of the National Academy of Sciences of the United States of America. 103: 16770-5. PMID 17075074 DOI: 10.1073/Pnas.0603501103  0.426
2006 Ng YS, Krilleke D, Shima DT. VEGF function in vascular pathogenesis. Experimental Cell Research. 312: 527-37. PMID 16330026 DOI: 10.1016/J.Yexcr.2005.11.008  0.692
2005 Lee JH, Canny MD, De Erkenez A, Krilleke D, Ng YS, Shima DT, Pardi A, Jucker F. A therapeutic aptamer inhibits angiogenesis by specifically targeting the heparin binding domain of VEGF165. Proceedings of the National Academy of Sciences of the United States of America. 102: 18902-7. PMID 16357200 DOI: 10.1073/Pnas.0509069102  0.547
2004 Ng YS, Ramsauer M, Loureiro RM, D'Amore PA. Identification of genes involved in VEGF-mediated vascular morphogenesis using embryonic stem cell-derived cystic embryoid bodies. Laboratory Investigation; a Journal of Technical Methods and Pathology. 84: 1209-18. PMID 15220937 DOI: 10.1038/Labinvest.3700150  0.765
2004 Chang R, Andreoli S, Ng YS, Truong T, Smith SR, Wilson J, D'Amore PA. VEGF expression is downregulated in nitrofen-induced congenital diaphragmatic hernia. Journal of Pediatric Surgery. 39: 825-8; discussion 82. PMID 15185205 DOI: 10.1016/J.Jpedsurg.2004.02.015  0.747
2003 Ishida S, Usui T, Yamashiro K, Kaji Y, Amano S, Ogura Y, Hida T, Oguchi Y, Ambati J, Miller JW, Gragoudas ES, Ng YS, D'Amore PA, Shima DT, Adamis AP. VEGF164-mediated inflammation is required for pathological, but not physiological, ischemia-induced retinal neovascularization. The Journal of Experimental Medicine. 198: 483-9. PMID 12900522 DOI: 10.1084/Jem.20022027  0.74
2002 D'Amore PA, Ng YS. Won't you be my neighbor? Local induction of arteriogenesis. Cell. 110: 289-92. PMID 12176316 DOI: 10.1016/S0092-8674(02)00869-3  0.642
2002 Galambos C, Ng YS, Ali A, Noguchi A, Lovejoy S, D'Amore PA, DeMello DE. Defective pulmonary development in the absence of heparin-binding vascular endothelial growth factor isoforms. American Journal of Respiratory Cell and Molecular Biology. 27: 194-203. PMID 12151311 DOI: 10.1165/Ajrcmb.27.2.4703  0.701
2002 D'Amore PA, Ng YS. Tales of the cryptic: unveiling more angiogenesis inhibitors. Trends in Molecular Medicine. 8: 313-5. PMID 12114105 DOI: 10.1016/S1471-4914(02)02367-5  0.527
2002 Zelzer E, McLean W, Ng YS, Fukai N, Reginato AM, Lovejoy S, D'Amore PA, Olsen BR. Skeletal defects in VEGF(120/120) mice reveal multiple roles for VEGF in skeletogenesis. Development (Cambridge, England). 129: 1893-904. PMID 11934855  0.737
2002 Stalmans I, Ng YS, Rohan R, Fruttiger M, Bouché A, Yuce A, Fujisawa H, Hermans B, Shani M, Jansen S, Hicklin D, Anderson DJ, Gardiner T, Hammes HP, Moons L, et al. Arteriolar and venular patterning in retinas of mice selectively expressing VEGF isoforms. The Journal of Clinical Investigation. 109: 327-36. PMID 11827992 DOI: 10.1172/Jci14362  0.752
2001 Ng YS, D'Amore PA. Therapeutic angiogenesis for cardiovascular disease. Current Controlled Trials in Cardiovascular Medicine. 2: 278-285. PMID 11806814 DOI: 10.1186/Cvm-2-6-278  0.693
2001 Ng YS, Rohan R, Sunday ME, Demello DE, D'Amore PA. Differential expression of VEGF isoforms in mouse during development and in the adult. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 220: 112-21. PMID 11169844 DOI: 10.1002/1097-0177(2000)9999:9999<::Aid-Dvdy1093>3.0.Co;2-D  0.753
1999 Carmeliet P, Ng YS, Nuyens D, Theilmeier G, Brusselmans K, Cornelissen I, Ehler E, Kakkar VV, Stalmans I, Mattot V, Perriard JC, Dewerchin M, Flameng W, Nagy A, Lupu F, et al. Impaired myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188. Nature Medicine. 5: 495-502. PMID 10229225 DOI: 10.1038/8379  0.74
1996 Shima DT, Kuroki M, Deutsch U, Ng YS, Adamis AP, D'Amore PA. The mouse gene for vascular endothelial growth factor. Genomic structure, definition of the transcriptional unit, and characterization of transcriptional and post-transcriptional regulatory sequences. The Journal of Biological Chemistry. 271: 3877-83. PMID 8632007 DOI: 10.1074/Jbc.271.7.3877  0.684
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