Year |
Citation |
Score |
2022 |
Laffey KG, Stiles RJ, Ludescher MJ, Davis TR, Khwaja SS, Bram RJ, Wettstein PJ, Ramachandran V, Parks CA, Reyes EE, Ferrer A, Canfield JM, Johnson CE, Hammer RD, Gil D, ... Schrum AG, et al. Early expression of mature αβ TCR in CD4CD8 T cell progenitors enables MHC to drive development of T-ALL bearing NOTCH mutations. Proceedings of the National Academy of Sciences of the United States of America. 119: e2118529119. PMID 35767640 DOI: 10.1073/pnas.2118529119 |
0.414 |
|
2022 |
Banerjee A, Li D, Guo Y, Mei Z, Lau C, Chen K, Westwick J, Klauda JB, Schrum A, Lazear ER, Krupnick AS. A reengineered common chain cytokine augments CD8+ T cell-dependent immunotherapy. Jci Insight. 7. PMID 35603788 DOI: 10.1172/jci.insight.158889 |
0.493 |
|
2020 |
Becher LRE, Nevala WK, Sutor SL, Abergel M, Hoffmann MM, Parks CA, Pease LR, Schrum AG, Markovic SN, Gil D. Public and private human T-cell clones respond differentially to HCMV antigen when boosted by CD3 copotentiation. Blood Advances. 4: 5343-5356. PMID 33125463 DOI: 10.1182/bloodadvances.2020002255 |
0.481 |
|
2020 |
Elsbernd L, Nelson A, Huynh H, Hoffmann M, Parks C, Nevala W, Sutor S, Pease L, Schrum A, Gil D, Markovic SN. Abstract B78: Co-potentiation of human T cells to identify subdominant tumor neoantigens from melanoma patients responding to immune checkpoint blockade Cancer Immunology Research. 8. DOI: 10.1158/2326-6074.Tumimm18-B78 |
0.356 |
|
2019 |
Onyema OO, Guo Y, Mahgoub B, Wang Q, Manafi A, Mei Z, Banerjee A, Li D, Stoler MH, Zaidi MT, Schrum AG, Kreisel D, Gelman AE, Jacobsen EA, Krupnick AS. Eosinophils downregulate lung alloimmunity by decreasing TCR signal transduction. Jci Insight. 4. PMID 31167966 DOI: 10.1172/Jci.Insight.128241 |
0.542 |
|
2019 |
Neier SC, Ferrer A, Wilton KM, Smith SEP, Kelcher AMH, Pavelko KD, Canfield JM, Davis TR, Stiles RJ, Chen Z, McCluskey J, Burrows SR, Rossjohn J, Hebrink DM, Carmona EM, ... ... Schrum AG, et al. The early proximal αβ TCR signalosome specifies thymic selection outcome through a quantitative protein interaction network. Science Immunology. 4. PMID 30770409 DOI: 10.1126/Sciimmunol.Aal2201 |
0.328 |
|
2019 |
Laffey KG, Stiles RJ, Ludescher M, Davis T, Khwaja SS, Bram RJ, Wettstein PJ, Ramachandran V, Johnson CE, Hammer R, Shyu C, Gil D, Schrum AG. A New Mechanism for T-ALL Leukemogenesis: Early Expression of Alpha-Beta TCR Occurs in a Natural Subset of CD4-CD8- Double Negative (DN) Thymocytes Where MHC Engagement May Drive NOTCH Mutation and Tumor Initiation Blood. 134: 1463-1463. DOI: 10.1182/Blood-2019-131897 |
0.457 |
|
2018 |
Ghraieb A, Keren A, Ginzburg A, Ullmann Y, Schrum AG, Paus R, Gilhar A. iNKT cells ameliorate human autoimmunity: Lessons from alopecia areata. Journal of Autoimmunity. PMID 29680372 DOI: 10.1016/j.jaut.2018.04.001 |
0.322 |
|
2018 |
Nelson AD, Elsbernd L, Schrum AG, Pages DG. Abstract 962: Testing T cell co-potentiation as an antitumor therapeutic strategy in humanized mouse models Immunology. DOI: 10.1158/1538-7445.Am2018-962 |
0.383 |
|
2017 |
Escalante P, Peikert T, Clain J, Keulen VV, Erskine C, Schrum A, Limper A. Combinatorial ELISPOT and T-cell immunoprofiling with CD25+/CD134+ co-expression in latent TB infection European Respiratory Journal. DOI: 10.1183/1393003.Congress-2017.Pa2691 |
0.466 |
|
2016 |
Goplen NP, Saxena V, Knudson KM, Schrum AG, Gil D, Daniels MA, Zamoyska R, Teixeiro E. IL-12 Signals through the TCR To Support CD8 Innate Immune Responses. Journal of Immunology (Baltimore, Md. : 1950). PMID 27521342 DOI: 10.4049/Jimmunol.1600037 |
0.524 |
|
2016 |
Smith SE, Neier SC, Reed BK, Davis TR, Sinnwell JP, Eckel-Passow JE, Sciallis GF, Wieland CN, Torgerson RR, Gil D, Neuhauser C, Schrum AG. Multiplex matrix network analysis of protein complexes in the human TCR signalosome. Science Signaling. 9: rs7. PMID 27485017 DOI: 10.1126/Scisignal.Aad7279 |
0.396 |
|
2016 |
Schrum AG, Neier SC, VanHook AM. Science Signaling Podcast for 2 August 2016: Patient-specific protein complexes. Science Signaling. 9: pc17. PMID 27485014 DOI: 10.1126/Scisignal.Aah5912 |
0.448 |
|
2016 |
Gilhar A, Schrum AG, Etzioni A, Waldmann H, Paus R. Alopecia areata: Animal models illuminate autoimmune pathogenesis and novel immunotherapeutic strategies. Autoimmunity Reviews. 15: 726-35. PMID 26971464 DOI: 10.1016/J.Autrev.2016.03.008 |
0.399 |
|
2016 |
Escalante P, Peikert T, Sasieta H, Keulen VV, Erskine C, Austin M, Dasari H, Schrum A, Limper A. A combinatorial dual-immunoassay predicts reactivation risk for patients with previously incomplete treatment for latent tuberculosis infection European Respiratory Journal. 48. DOI: 10.1183/13993003.Congress-2016.Pa2115 |
0.401 |
|
2015 |
Smith SE, Maus RL, Davis TR, Sundberg JP, Gil D, Schrum AG. Maternal IL-6 can cause T cell-mediated juvenile alopecia by non-scarring follicular dystrophy in mice. Experimental Dermatology. PMID 26660334 DOI: 10.1111/Exd.12914 |
0.316 |
|
2015 |
Hoffmann MM, Molina-Mendiola C, Nelson AD, Parks CA, Reyes EE, Hansen MJ, Rajagopalan G, Pease LR, Schrum AG, Gil D. Co-potentiation of antigen recognition: A mechanism to boost weak T cell responses and provide immunotherapy in vivo. Science Advances. 1: e1500415. PMID 26601285 DOI: 10.1126/Sciadv.1500415 |
0.556 |
|
2015 |
Reed BK, Chopp LB, Malo CS, Renner DN, Van Keulen VS, Girtman MA, Nevala WN, Pavelko KD, Gil D, Schrum AG, Johnson AJ, Pease LR. A Versatile Simple Capture Assay for Assessing the Structural Integrity of MHC Multimer Reagents. Plos One. 10: e0137984. PMID 26389800 DOI: 10.1371/Journal.Pone.0137984 |
0.375 |
|
2014 |
Reed BK, Lee KA, Bell MP, Gil D, Schrum AG. Detection of constant domain of human T cell antigen receptor alpha-chain via novel monoclonal antibody 7F18. Monoclonal Antibodies in Immunodiagnosis and Immunotherapy. 33: 386-92. PMID 25545207 DOI: 10.1089/Mab.2013.0086 |
0.401 |
|
2014 |
Smith SE, Neier SC, Davis TR, Pittelkow MR, Gil D, Schrum AG. Signalling protein complexes isolated from primary human skin-resident T cells can be analysed by Multiplex IP-FCM. Experimental Dermatology. 23: 272-3. PMID 24588717 DOI: 10.1111/Exd.12362 |
0.488 |
|
2013 |
Neier SC, Smith SE, Davis TR, Gil D, Schrum AG. Toward T cell protein-protein interaction activity relevant to alopecia areata. The Journal of Investigative Dermatology. Symposium Proceedings / the Society For Investigative Dermatology, Inc. [and] European Society For Dermatological Research. 16: S31-3. PMID 24326546 DOI: 10.1038/Jidsymp.2013.9 |
0.503 |
|
2013 |
Ferrer A, Schrum AG, Gil D. A PCR-Based Method to Genotype Mice Knocked Out for All Four CD3 Subunits, the Standard Recipient Strain for Retrogenic TCR/CD3 Bone Marrow Reconstitution Technology. Bioresearch Open Access. 2: 222-6. PMID 23741635 DOI: 10.1089/Biores.2013.0002 |
0.405 |
|
2012 |
Schrum AG, Gil D. Robustness and Specificity in Signal Transduction via Physiologic Protein Interaction Networks. Clinical & Experimental Pharmacology. 2: S3.001. PMID 24535485 DOI: 10.4172/2161-1459.S3-001 |
0.302 |
|
2012 |
Nelson AD, Hoffmann MM, Parks CA, Dasari S, Schrum AG, Gil D. IgG Fab fragments forming bivalent complexes by a conformational mechanism that is reversible by osmolytes. The Journal of Biological Chemistry. 287: 42936-50. PMID 23109335 DOI: 10.1074/Jbc.M112.410217 |
0.348 |
|
2012 |
Smith SE, Bida AT, Davis TR, Sicotte H, Patterson SE, Gil D, Schrum AG. IP-FCM measures physiologic protein-protein interactions modulated by signal transduction and small-molecule drug inhibition. Plos One. 7: e45722. PMID 23029201 DOI: 10.1371/Journal.Pone.0045722 |
0.505 |
|
2012 |
Bida AT, Gil D, Schrum AG. Multiplex IP-FCM (immunoprecipitation-flow cytometry): Principles and guidelines for assessing physiologic protein-protein interactions in multiprotein complexes. Methods (San Diego, Calif.). 56: 154-60. PMID 21945581 DOI: 10.1016/J.Ymeth.2011.09.005 |
0.336 |
|
2011 |
Schrum AG, Gil D, Turka LA, Palmer E. Physical and functional bivalency observed among TCR/CD3 complexes isolated from primary T cells. Journal of Immunology (Baltimore, Md. : 1950). 187: 870-8. PMID 21666056 DOI: 10.4049/Jimmunol.1100538 |
0.618 |
|
2011 |
de la Cruz J, Kruger T, Parks CA, Silge RL, van Oers NS, Luescher IF, Schrum AG, Gil D. Basal and antigen-induced exposure of the proline-rich sequence in CD3ε. Journal of Immunology (Baltimore, Md. : 1950). 186: 2282-90. PMID 21228347 DOI: 10.4049/Jimmunol.1003225 |
0.43 |
|
2010 |
Davis TR, Schrum AG. IP-FCM: immunoprecipitation detected by flow cytometry. Journal of Visualized Experiments : Jove. PMID 21178959 DOI: 10.3791/2066 |
0.325 |
|
2010 |
Mirza N, Duque MA, Dominguez AL, Schrum AG, Dong H, Lustgarten J. B7-H1 expression on old CD8+ T cells negatively regulates the activation of immune responses in aged animals. Journal of Immunology (Baltimore, Md. : 1950). 184: 5466-74. PMID 20375308 DOI: 10.4049/Jimmunol.0903561 |
0.515 |
|
2010 |
Nagaraj S, Schrum AG, Cho HI, Celis E, Gabrilovich DI. Mechanism of T cell tolerance induced by myeloid-derived suppressor cells. Journal of Immunology (Baltimore, Md. : 1950). 184: 3106-16. PMID 20142361 DOI: 10.4049/Jimmunol.0902661 |
0.548 |
|
2009 |
Schrum AG. Visualization of multiprotein complexes by flow cytometry. Current Protocols in Immunology / Edited by John E. Coligan ... [Et Al.]. Unit5.9. PMID 19918948 DOI: 10.1002/0471142735.Im0509S87 |
0.337 |
|
2009 |
Teixeiro E, Daniels MA, Hamilton SE, Schrum AG, Bragado R, Jameson SC, Palmer E. Different T cell receptor signals determine CD8+ memory versus effector development. Science (New York, N.Y.). 323: 502-5. PMID 19164748 DOI: 10.1126/Science.1163612 |
0.518 |
|
2008 |
Gil D, Schrum AG, Daniels MA, Palmer E. A role for CD8 in the developmental tuning of antigen recognition and CD3 conformational change. Journal of Immunology (Baltimore, Md. : 1950). 180: 3900-9. PMID 18322198 DOI: 10.4049/Jimmunol.180.6.3900 |
0.535 |
|
2007 |
Schrum AG, Gil D, Dopfer EP, Wiest DL, Turka LA, Schamel WW, Palmer E. High-sensitivity detection and quantitative analysis of native protein-protein interactions and multiprotein complexes by flow cytometry. Science's Stke : Signal Transduction Knowledge Environment. 2007: pl2. PMID 17551170 DOI: 10.1126/Stke.3892007Pl2 |
0.574 |
|
2005 |
Gil D, Schrum AG, Alarcón B, Palmer E. T cell receptor engagement by peptide-MHC ligands induces a conformational change in the CD3 complex of thymocytes. The Journal of Experimental Medicine. 201: 517-22. PMID 15728235 DOI: 10.1084/Jem.20042036 |
0.481 |
|
2005 |
Schrum AG, Palmer E, Turka LA. Distinct temporal programming of naive CD4+ T cells for cell division versus TCR-dependent death susceptibility by antigen-presenting macrophages. European Journal of Immunology. 35: 449-59. PMID 15682456 DOI: 10.1002/Eji.200425635 |
0.639 |
|
2004 |
Teixeiro E, Daniels MA, Hausmann B, Schrum AG, Naeher D, Luescher I, Thome M, Bragado R, Palmer E. T cell division and death are segregated by mutation of TCRbeta chain constant domains. Immunity. 21: 515-26. PMID 15485629 DOI: 10.1016/J.Immuni.2004.08.014 |
0.45 |
|
2003 |
Schrum AG, Turka LA, Palmer E. Surface T-cell antigen receptor expression and availability for long-term antigenic signaling. Immunological Reviews. 196: 7-24. PMID 14617194 DOI: 10.1046/J.1600-065X.2003.00083.X |
0.626 |
|
2002 |
Schrum AG, Turka LA. The proliferative capacity of individual naive CD4(+) T cells is amplified by prolonged T cell antigen receptor triggering. The Journal of Experimental Medicine. 196: 793-803. PMID 12235212 DOI: 10.1084/Jem.20020158 |
0.665 |
|
2000 |
Schrum AG, Wells AD, Turka LA. Enhanced surface TCR replenishment mediated by CD28 leads to greater TCR engagement during primary stimulation. International Immunology. 12: 833-42. PMID 10837411 DOI: 10.1093/Intimm/12.6.833 |
0.639 |
|
2000 |
Schrum AG, Pradhan M, Wells AD, Turka LA. REGULATION OF TCR SURFACE EXPRESSION DURING T CELL ACTIVATION: A NEW MECHANISM OF ACTION OF CD28 COSTIMULATION.: Abstract# 75 Transplantation. 69. DOI: 10.1097/00007890-200004271-00075 |
0.621 |
|
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