| Year |
Citation |
Score |
| 2018 |
Yeh ST, Zambrano CM, Koch WJ, Purcell NH. PH domain leucine-rich repeat protein phosphatase 2 (PHLPP2) Regulates G-protein coupled Receptor Kinase 5 (GRK5) induced Cardiac Hypertrophy . The Journal of Biological Chemistry. PMID 29628444 DOI: 10.1074/jbc.M117.809913 |
0.416 |
|
| 2013 |
Dusaban SS, Purcell NH, Rockenstein E, Masliah E, Cho MK, Smrcka AV, Brown JH. Phospholipase C epsilon links G protein-coupled receptor activation to inflammatory astrocytic responses. Proceedings of the National Academy of Sciences of the United States of America. 110: 3609-14. PMID 23401561 DOI: 10.1073/Pnas.1217355110 |
0.475 |
|
| 2008 |
Maillet M, Purcell NH, Sargent MA, York AJ, Bueno OF, Molkentin JD. DUSP6 (MKP3) null mice show enhanced ERK1/2 phosphorylation at baseline and increased myocyte proliferation in the heart affecting disease susceptibility. The Journal of Biological Chemistry. 283: 31246-55. PMID 18753132 DOI: 10.1074/Jbc.M806085200 |
0.338 |
|
| 2007 |
Purcell NH, Wilkins BJ, York A, Saba-El-Leil MK, Meloche S, Robbins J, Molkentin JD. Genetic inhibition of cardiac ERK1/2 promotes stress-induced apoptosis and heart failure but has no effect on hypertrophy in vivo. Proceedings of the National Academy of Sciences of the United States of America. 104: 14074-9. PMID 17709754 DOI: 10.1073/Pnas.0610906104 |
0.375 |
|
| 2004 |
Lips DJ, Bueno OF, Wilkins BJ, Purcell NH, Kaiser RA, Lorenz JN, Voisin L, Saba-El-Leil MK, Meloche S, Pouysségur J, Pagès G, De Windt LJ, Doevendans PA, Molkentin JD. MEK1-ERK2 signaling pathway protects myocardium from ischemic injury in vivo. Circulation. 109: 1938-41. PMID 15096454 DOI: 10.1161/01.Cir.0000127126.73759.23 |
0.308 |
|
| 2004 |
Purcell NH, Darwis D, Bueno OF, Müller JM, Schüle R, Molkentin JD. Extracellular signal-regulated kinase 2 interacts with and is negatively regulated by the LIM-only protein FHL2 in cardiomyocytes. Molecular and Cellular Biology. 24: 1081-95. PMID 14729955 DOI: 10.1128/Mcb.24.3.1081-1095.2004 |
0.449 |
|
| 2003 |
Purcell NH, Molkentin JD. Is nuclear factor kappaB an attractive therapeutic target for treating cardiac hypertrophy? Circulation. 108: 638-40. PMID 12912791 DOI: 10.1161/01.Cir.0000085362.40608.Dd |
0.511 |
|
| 2002 |
Gupta S, Purcell NH, Lin A, Sen S. Activation of nuclear factor-kappaB is necessary for myotrophin-induced cardiac hypertrophy. The Journal of Cell Biology. 159: 1019-28. PMID 12486112 DOI: 10.1083/Jcb.200207149 |
0.762 |
|
| 2001 |
Tang G, Minemoto Y, Dibling B, Purcell NH, Li Z, Karin M, Lin A. Inhibition of JNK activation through NF-kappaB target genes. Nature. 414: 313-7. PMID 11713531 DOI: 10.1038/35104568 |
0.672 |
|
| 2001 |
Purcell NH, Tang G, Yu C, Mercurio F, DiDonato JA, Lin A. Activation of NF-kappa B is required for hypertrophic growth of primary rat neonatal ventricular cardiomyocytes. Proceedings of the National Academy of Sciences of the United States of America. 98: 6668-73. PMID 11381115 DOI: 10.1073/Pnas.111155798 |
0.607 |
|
| 2001 |
Purcell NH, Yu C, He D, Xiang J, Paran N, DiDonato JA, Yamaoka S, Shaul Y, Lin A. Activation of NF-kappaB by hepatitis B virus X protein through an IkappaB kinase-independent mechanism. American Journal of Physiology. Gastrointestinal and Liver Physiology. 280: G669-77. PMID 11254493 DOI: 10.1152/Ajpgi.2001.280.4.G669 |
0.603 |
|
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