Zachary Freyberg, M.D., Ph.D. - Publications

Affiliations: 
2004 Yeshiva University, New York, NY, United States 
 2004-2008 Psychiatry New York Presbyterian Hospital/Weill Cornell Medical Center, New York, NY, United States 
 2008-2016 Psychiatry Columbia / New York State Psychiatric Institute 
 2016- University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Cell Biology, Molecular Biology

37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Phan BN, Ray MH, Xue X, Fu C, Fenster RJ, Kohut SJ, Bergman J, Haber SN, McCullough KM, Fish MK, Glausier JR, Su Q, Tipton AE, Lewis DA, Freyberg Z, et al. Single nuclei transcriptomics in human and non-human primate striatum in opioid use disorder. Nature Communications. 15: 878. PMID 38296993 DOI: 10.1038/s41467-024-45165-7  0.304
2023 Buck SA, Rubin SA, Kunkhyen T, Treiber CD, Xue X, Fenno LE, Mabry SJ, Sundar VR, Yang Z, Shah D, Ketchesin KD, Becker-Krail DD, Vasylieva I, Smith MC, Weisel FJ, ... ... Freyberg Z, et al. Sexually dimorphic mechanisms of VGLUT-mediated protection from dopaminergic neurodegeneration. Biorxiv : the Preprint Server For Biology. PMID 37873436 DOI: 10.1101/2023.10.02.560584  0.798
2023 Enriquez-Traba J, Yarur-Castillo HE, Flores RJ, Weil T, Roy S, Usdin TB, LaGamma CT, Arenivar M, Wang H, Tsai VS, Moritz AE, Sibley DR, Moratalla R, Freyberg ZZ, Tejeda HA. Dissociable control of motivation and reinforcement by distinct ventral striatal dopamine receptors. Biorxiv : the Preprint Server For Biology. PMID 37425766 DOI: 10.1101/2023.06.27.546539  0.398
2023 Gayden J, Puig S, Srinivasan C, Buck SA, Gamble MC, Glausier JR, Tejeda HA, Dong Y, Pfenning AR, Logan RW, Freyberg Z. Three-dimensional characterization of medium spiny neuron heterogeneity in the adult mouse striatum. Biorxiv : the Preprint Server For Biology. PMID 37205475 DOI: 10.1101/2023.05.04.539488  0.781
2022 Adamson A, Buck SA, Freyberg Z, De Miranda BR. Sex Differences in Dopaminergic Vulnerability to Environmental Toxicants - Implications for Parkinson's Disease. Current Environmental Health Reports. PMID 36201109 DOI: 10.1007/s40572-022-00380-6  0.734
2022 Buck SA, Quincy Erickson-Oberg M, Logan RW, Freyberg Z. Relevance of interactions between dopamine and glutamate neurotransmission in schizophrenia. Molecular Psychiatry. PMID 35681081 DOI: 10.1038/s41380-022-01649-w  0.774
2022 Buck SA, Erickson-Oberg MQ, Bhatte SH, McKellar CD, Ramanathan VP, Rubin SA, Freyberg Z. Roles of VGLUT2 and Dopamine/Glutamate Co-Transmission in Selective Vulnerability to Dopamine Neurodegeneration. Acs Chemical Neuroscience. PMID 34994539 DOI: 10.1021/acschemneuro.1c00741  0.806
2021 Steinkellner T, Conrad WS, Kovacs I, Rissman RA, Lee EB, Trojanowski JQ, Freyberg Z, Roy S, Luk KC, Lee VM, Hnasko TS. Dopamine neurons exhibit emergent glutamatergic identity in Parkinson's disease. Brain : a Journal of Neurology. PMID 35258081 DOI: 10.1093/brain/awab373  0.442
2021 Buck SA, Steinkellner T, Aslanoglou D, Villeneuve M, Bhatte SH, Childers VC, Rubin SA, De Miranda BR, O'Leary EI, Neureiter EG, Fogle KJ, Palladino MJ, Logan RW, Glausier JR, Fish KN, ... ... Freyberg Z, et al. Vesicular glutamate transporter modulates sex differences in dopamine neuron vulnerability to age-related neurodegeneration. Aging Cell. e13365. PMID 33909313 DOI: 10.1111/acel.13365  0.792
2021 Buck SA, Miranda BR, Logan RW, Fish KN, Greenamyre JT, Freyberg Z. VGLUT2 is a determinant of dopamine neuron resilience in a rotenone model of dopamine neurodegeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 33893220 DOI: 10.1523/JNEUROSCI.2770-20.2021  0.8
2021 Aslanoglou D, Bertera S, Sánchez-Soto M, Benjamin Free R, Lee J, Zong W, Xue X, Shrestha S, Brissova M, Logan RW, Wollheim CB, Trucco M, Yechoor VK, Sibley DR, Bottino R, ... Freyberg Z, et al. Dopamine regulates pancreatic glucagon and insulin secretion via adrenergic and dopaminergic receptors. Translational Psychiatry. 11: 59. PMID 33589583 DOI: 10.1038/s41398-020-01171-z  0.316
2020 Gayden JD, Freyberg Z. Commentary: Ghrelin promotes midbrain neural stem cells differentiation to dopaminergic neurons through the Wnt/β-catenin pathway. Frontiers in Cellular Neuroscience. 14: 248. PMID 32973452 DOI: 10.3389/Fncel.2020.00248  0.348
2020 Buck SA, Torregrossa MM, Logan RW, Freyberg Z. Roles of Dopamine and Glutamate Co-Release in the Nucleus Accumbens in Mediating the Actions of Drugs of Abuse. The Febs Journal. PMID 32702182 DOI: 10.1111/Febs.15496  0.785
2020 Fiala T, Wang J, Dunn M, Šebej P, Choi SJ, Nwadibia EC, Fialova E, Martinez DM, Cheetham CE, Fogle KJ, Palladino MJ, Freyberg Z, Sulzer D, Sames D. Chemical Targeting of Voltage Sensitive Dyes to Specific Cells and Molecules in the Brain. Journal of the American Chemical Society. PMID 32395989 DOI: 10.1021/Jacs.0C00861  0.306
2020 Carter SD, Hampton CM, Langlois R, Melero R, Farino ZJ, Calderon MJ, Li W, Wallace CT, Tran NH, Grassucci RA, Siegmund SE, Pemberton J, Morgenstern TJ, Eisenman L, Aguilar JI, ... ... Freyberg Z, et al. Ribosome-associated vesicles: A dynamic subcompartment of the endoplasmic reticulum in secretory cells. Science Advances. 6: eaay9572. PMID 32270040 DOI: 10.1126/Sciadv.Aay9572  0.515
2019 Wei H, Zapata RC, Lopez-Valencia M, Aslanoglou D, Farino ZJ, Benner V, Osborn O, Freyberg Z, McCarthy MJ. Dopamine D receptor signaling modulates pancreatic beta cell circadian rhythms. Psychoneuroendocrinology. 113: 104551. PMID 31884319 DOI: 10.1016/J.Psyneuen.2019.104551  0.396
2019 Han F, Konkalmatt P, Mokashi C, Kumar M, Zhang Y, Ko A, Farino ZJ, Asico LD, Xu G, Gildea J, Zheng X, Felder RA, Lee REC, Jose PA, Freyberg Z, et al. Dopamine D receptor modulates Wnt expression and control of cell proliferation. Scientific Reports. 9: 16861. PMID 31727925 DOI: 10.1038/S41598-019-52528-4  0.336
2019 Farino ZJ, Morgenstern TJ, Maffei A, Quick M, De Solis AJ, Wiriyasermkul P, Freyberg RJ, Aslanoglou D, Sorisio D, Inbar BP, Free RB, Donthamsetti P, Mosharov EV, Kellendonk C, Schwartz GJ, ... ... Freyberg Z, et al. New roles for dopamine D and D receptors in pancreatic beta cell insulin secretion. Molecular Psychiatry. PMID 30626912 DOI: 10.1038/S41380-018-0344-6  0.77
2019 Konkalmatt P, Kumar M, Asico L, Freyberg Z, Jose PA, Armando I. Abstract 134: Dopamine D 2 Receptor Modulates Wnt Expression and Control of Cell Proliferation Hypertension. 74. DOI: 10.1161/Hyp.74.Suppl_1.134  0.344
2019 Chipchura D, Wei H, Freyberg Z, Leckband S, McCarthy M. 51. D2 Dopamine Receptors Alter Circadian Rhythms in Pancreatic Islet Cells: Implications for the Metabolic Side Effects of Antipsychotic Drugs Biological Psychiatry. 85: S21. DOI: 10.1016/J.Biopsych.2019.03.065  0.394
2019 Freyberg Z, Farino Z, Morgenstern T, Maffei A, Quick M, De Solis A, Wiriyasermkul P, Freyberg R, Aslanoglou D, Sorisio D, Inbar B, Free RB, Donthamsetti P, Mosharov E, Kellendonk C, et al. 50. New Roles for Peripheral Dopamine D2-Like Receptors in Antipsychotic Drug-Induced Metabolic Dysfunction Biological Psychiatry. 85: S21. DOI: 10.1016/J.Biopsych.2019.03.064  0.585
2018 Freyberg Z, Logan RW. The Intertwined Roles of Circadian Rhythms and Neuronal Metabolism Fueling Drug Reward and Addiction. Current Opinion in Physiology. 5: 80-89. PMID 30631826 DOI: 10.1016/J.Cophys.2018.08.004  0.433
2018 Chipchura DA, Freyberg Z, Edwards C, Leckband SG, McCarthy MJ. Does the Time of Drug Administration Alter the Metabolic Risk of Aripiprazole? Frontiers in Psychiatry. 9: 494. PMID 30364286 DOI: 10.3389/Fpsyt.2018.00494  0.309
2018 Steinkellner T, Zell V, Farino ZJ, Sonders MS, Villeneuve M, Freyberg RJ, Przedborski S, Lu W, Freyberg Z, Hnasko TS. Role for VGLUT2 in selective vulnerability of midbrain dopamine neurons. The Journal of Clinical Investigation. PMID 29337309 DOI: 10.1172/Jci95795  0.517
2017 Aguilar JI, Dunn M, Mingote S, Karam CS, Farino ZJ, Sonders MS, Choi SJ, Grygoruk A, Zhang Y, Cela C, Choi BJ, Flores J, Freyberg RJ, McCabe BD, Mosharov EV, ... ... Freyberg Z, et al. Neuronal Depolarization Drives Increased Dopamine Synaptic Vesicle Loading via VGLUT. Neuron. PMID 28823729 DOI: 10.1016/J.Neuron.2017.07.038  0.646
2017 Freyberg Z, McCarthy MJ. Dopamine D2 receptors and the circadian clock reciprocally mediate antipsychotic drug-induced metabolic disturbances. Npj Schizophrenia. 3: 17. PMID 28560263 DOI: 10.1038/s41537-017-0018-4  0.333
2016 Freyberg Z, Sonders MS, Aguilar JI, Hiranita T, Karam CS, Flores J, Pizzo AB, Zhang Y, Farino ZJ, Chen A, Martin CA, Kopajtic TA, Fei H, Hu G, Lin YY, et al. Mechanisms of amphetamine action illuminated through optical monitoring of dopamine synaptic vesicles in Drosophila brain. Nature Communications. 7: 10652. PMID 26879809 DOI: 10.1038/Ncomms10652  0.608
2016 Farino ZJ, Morgenstern TJ, Vallaghe J, Gregor N, Donthamsetti P, Harris PE, Pierre N, Freyberg R, Charrier-Savournin F, Javitch JA, Freyberg Z. Development of a Rapid Insulin Assay by Homogenous Time-Resolved Fluorescence. Plos One. 11: e0148684. PMID 26849707 DOI: 10.1371/Journal.Pone.0148684  0.48
2013 Pizzo AB, Karam CS, Zhang Y, Yano H, Freyberg RJ, Karam DS, Freyberg Z, Yamamoto A, McCabe BD, Javitch JA. The membrane raft protein Flotillin-1 is essential in dopamine neurons for amphetamine-induced behavior in Drosophila. Molecular Psychiatry. 18: 824-33. PMID 22710269 DOI: 10.1038/Mp.2012.82  0.706
2012 Simpson N, Maffei A, Freeby M, Burroughs S, Freyberg Z, Javitch J, Leibel RL, Harris PE. Dopamine-mediated autocrine inhibitory circuit regulating human insulin secretion in vitro. Molecular Endocrinology (Baltimore, Md.). 26: 1757-72. PMID 22915827 DOI: 10.1210/Me.2012-1101  0.542
2010 Karam CS, Ballon JS, Bivens NM, Freyberg Z, Girgis RR, Lizardi-Ortiz JE, Markx S, Lieberman JA, Javitch JA. Signaling pathways in schizophrenia: emerging targets and therapeutic strategies. Trends in Pharmacological Sciences. 31: 381-90. PMID 20579747 DOI: 10.1016/J.Tips.2010.05.004  0.529
2010 Freyberg Z, Ferrando SJ, Javitch JA. Roles of the Akt/GSK-3 and Wnt signaling pathways in schizophrenia and antipsychotic drug action. The American Journal of Psychiatry. 167: 388-96. PMID 19917593 DOI: 10.1176/Appi.Ajp.2009.08121873  0.53
2003 Freyberg Z, Siddhanta A, Shields D. "Slip, sliding away": phospholipase D and the Golgi apparatus. Trends in Cell Biology. 13: 540-6. PMID 14507482 DOI: 10.1016/J.Tcb.2003.08.004  0.649
2002 Freyberg Z, Bourgoin S, Shields D. Phospholipase D2 is localized to the rims of the Golgi apparatus in mammalian cells. Molecular Biology of the Cell. 13: 3930-42. PMID 12429836 DOI: 10.1091/Mbc.02-04-0059  0.669
2001 Freyberg Z, Sweeney D, Siddhanta A, Bourgoin S, Frohman M, Shields D. Intracellular localization of phospholipase D1 in mammalian cells. Molecular Biology of the Cell. 12: 943-55. PMID 11294898 DOI: 10.1091/Mbc.12.4.943  0.75
1998 Floyd S, Butler MH, Cremona O, David C, Freyberg Z, Zhang X, Solimena M, Tokunaga A, Ishizu H, Tsutsui K, De Camilli P. Expression of amphiphysin I, an autoantigen of paraneoplastic neurological syndromes, in breast cancer. Molecular Medicine (Cambridge, Mass.). 4: 29-39. PMID 9513187 DOI: 10.1007/Bf03401727  0.463
1997 Butler MH, David C, Ochoa GC, Freyberg Z, Daniell L, Grabs D, Cremona O, De Camilli P. Amphiphysin II (SH3P9; BIN1), a member of the amphiphysin/Rvs family, is concentrated in the cortical cytomatrix of axon initial segments and nodes of ranvier in brain and around T tubules in skeletal muscle. The Journal of Cell Biology. 137: 1355-67. PMID 9182667 DOI: 10.1083/Jcb.137.6.1355  0.466
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