Year |
Citation |
Score |
2015 |
Xu Z, Shaw BR. Synthesis, Hydrolysis, and Protonation-Promoted Intramolecular Reductive Breakdown of Potential NRTIs: Stavudine α-P-Borano-γ-P-N-l-tryptophanyltriphosphates. Molecules (Basel, Switzerland). 20: 18808-18826. PMID 26556316 DOI: 10.3390/Molecules201018808 |
0.383 |
|
2014 |
Xu Z, Shaw BR. Phosphorus deprotonation by a non-nucleophilic base is critical for the synthesis of nucleoside α-P-boranodiphosphates via a phosphoramidite approach Tetrahedron Letters. 55: 5605-5608. DOI: 10.1016/J.Tetlet.2014.08.047 |
0.363 |
|
2013 |
Cheek MA, Sharaf ML, Dobrikov MI, Shaw BR. Inhibition of hepatitis C viral RNA-dependent RNA polymerase by α-P-boranophosphate nucleotides: exploring a potential strategy for mechanism-based HCV drug design. Antiviral Research. 98: 144-52. PMID 23466667 DOI: 10.1016/J.Antiviral.2013.02.014 |
0.745 |
|
2013 |
Xu Z, Sergueeva ZA, Shaw BR. Synthesis and hydrolytic properties of thymidine boranomonophosphate Tetrahedron Letters. 54: 2882-2885. DOI: 10.1016/J.Tetlet.2013.03.110 |
0.338 |
|
2012 |
Ray P, Cheek MA, Sharaf ML, Li N, Ellington AD, Sullenger BA, Shaw BR, White RR. Aptamer-mediated delivery of chemotherapy to pancreatic cancer cells. Nucleic Acid Therapeutics. 22: 295-305. PMID 23030589 DOI: 10.1089/Nat.2012.0353 |
0.73 |
|
2011 |
Johnson CN, Spring AM, Sergueev D, Shaw BR, Germann MW. Structural basis of the RNase H1 activity on stereo regular borano phosphonate DNA/RNA hybrids. Biochemistry. 50: 3903-12. PMID 21443203 DOI: 10.1021/Bi200083D |
0.388 |
|
2008 |
Shaw BR, Moussa L, Sharaf M, Cheek M, Dobrikov M. Boranophosphate siRNA-aptamer chimeras for tumor-specific downregulation of cancer receptors and modulators. Nucleic Acids Symposium Series (2004). 655-6. PMID 18776550 DOI: 10.1093/nass/nrn331 |
0.687 |
|
2008 |
Cheek MA, Dobrikov MI, Wennefors CK, Xu Z, Hashmi SN, Shen X, Shaw BR. Synthesis and properties of (alpha-P-borano)-nucleoside 5'-triphosphate analogues as potential antiviral agents. Nucleic Acids Symposium Series (2004). 81-2. PMID 18776263 DOI: 10.1093/nass/nrn041 |
0.759 |
|
2008 |
Wennefors CK, Dobrikov MI, Xu Z, Li P, Shaw BR. Stereospecificity, substrate, and inhibitory properties of nucleoside diphosphate analogs for creatine and pyruvate kinases. Bioorganic Chemistry. 36: 169-77. PMID 18433830 DOI: 10.1016/J.Bioorg.2008.03.001 |
0.758 |
|
2007 |
Khan SI, Shaw BR. Efficient synthesis of thymidine boranophosphoramidates conjugated with amino acids. Nucleosides, Nucleotides & Nucleic Acids. 26: 621-3. PMID 18066867 DOI: 10.1080/15257770701490415 |
0.319 |
|
2007 |
Liu H, Hashmi SN, Shaw BR. Synthesis of 9-fluorenemethyl boranophosphonodiphosphate via an H-phosphonate approach. Nucleosides, Nucleotides & Nucleic Acids. 26: 1455-7. PMID 18066805 DOI: 10.1080/15257770701542413 |
0.442 |
|
2006 |
Hall AH, Wan J, Spesock A, Sergueeva Z, Shaw BR, Alexander KA. High potency silencing by single-stranded boranophosphate siRNA. Nucleic Acids Research. 34: 2773-81. PMID 16717282 DOI: 10.1093/Nar/Gkl339 |
0.498 |
|
2005 |
Li P, Xu Z, Liu H, Wennefors CK, Dobrikov MI, Ludwig J, Shaw BR. Synthesis of alpha-P-modified nucleoside diphosphates with ethylenediamine. Journal of the American Chemical Society. 127: 16782-3. PMID 16316213 DOI: 10.1021/Ja055179Y |
0.766 |
|
2005 |
Khan SI, Dobrikov MI, Shaw BR. Synthesis of 5-ethynyl-2'-deoxyuridine-5'-boranomono phosphate as a potential thymidylate synthase inhibitor. Nucleosides, Nucleotides & Nucleic Acids. 24: 1047-9. PMID 16248089 DOI: 10.1081/Ncn-200060046 |
0.33 |
|
2005 |
Dobrikov MI, Shaw BR. Affinity of (alpha-P-borano)-NTP analogs to rabbit muscle pyruvate kinase. Nucleosides, Nucleotides & Nucleic Acids. 24: 983-7. PMID 16248077 DOI: 10.1081/Ncn-200059378 |
0.351 |
|
2005 |
Wang JX, Sergueev DS, Shaw BR. The effect of a single boranophosphate substitution with defined configuration on the thermal stability and conformation of a DNA duplex. Nucleosides, Nucleotides & Nucleic Acids. 24: 951-5. PMID 16248070 DOI: 10.1081/Ncn-200059310 |
0.527 |
|
2005 |
Wang JX, Shaw BR. Synthesis of 5-(1-propynyl)-2'-deoxyuridine 5'-(alpha-P-borano)triphosphate and kinetic characterization as a substrate for mmlv reverse transcriptase. Nucleosides, Nucleotides & Nucleic Acids. 24: 947-50. PMID 16248069 DOI: 10.1081/Ncn-200059307 |
0.609 |
|
2005 |
Wan J, Shaw BR. Incorporation of ribonucleoside 5'-(alpha-P-borano)triphosphates into a 20-mer RNA by T7 RNA polymerase. Nucleosides, Nucleotides & Nucleic Acids. 24: 943-6. PMID 16248068 DOI: 10.1081/Ncn-200059303 |
0.508 |
|
2005 |
Li P, Shaw BR. Model synthesis of nucleoside boranophosphoramidate with amino acid for prodrug purpose. Nucleosides, Nucleotides & Nucleic Acids. 24: 675-8. PMID 16248012 DOI: 10.1081/Ncn-200060244 |
0.308 |
|
2005 |
Li P, Shaw BR. Synthesis of nucleoside boranophosphoramidate prodrugs conjugated with amino acids. The Journal of Organic Chemistry. 70: 2171-83. PMID 15760202 DOI: 10.1021/Jo0481248 |
0.312 |
|
2004 |
Hall AHS, Wan J, Shaughnessy EE, Shaw BR, Alexander KA. RNA interference using boranophosphate siRNAs: Structure-activity relationships Nucleic Acids Research. 32: 5991-6000. PMID 15545637 DOI: 10.1093/Nar/Gkh936 |
0.507 |
|
2004 |
Li P, Shaw BR. Convenient synthesis of nucleoside borane diphosphate analogues: deoxy- and ribonucleoside 5'-P(alpha)-boranodiphosphates. The Journal of Organic Chemistry. 69: 7051-7. PMID 15471452 DOI: 10.1021/jo049094b |
0.311 |
|
2003 |
Shaw BR, Dobrikov M, Wang X, Wan J, He K, Lin JL, Li P, Rait V, Sergueeva ZA, Sergueev D. Reading, writing, and modulating genetic information with boranophosphate mimics of nucleotides, DNA, and RNA. Annals of the New York Academy of Sciences. 1002: 12-29. PMID 14751819 DOI: 10.1196/Annals.1281.004 |
0.762 |
|
2003 |
Dobrikov MI, Sergueeva ZA, Shaw BR. Incorporation of (alpha-P-borano)-2',3'-dideoxycytidine 5'-triphosphate into DNA by drug-resistant MMLV reverse transcriptase and Taq DNA polymerase. Nucleosides, Nucleotides & Nucleic Acids. 22: 1651-5. PMID 14565487 DOI: 10.1002/CHIN.200409205 |
0.386 |
|
2003 |
Wang X, Dobrikov M, Sergueev D, Shaw BR. RNase H activation by stereoregular boranophosphate oligonucleotide. Nucleosides, Nucleotides & Nucleic Acids. 22: 1151-3. PMID 14565367 DOI: 10.1081/Ncn-120022823 |
0.344 |
|
2003 |
Li P, Shaw BR. One-pot synthesis of an AZT boranophosphate conjugated with tyrosine: a potential prodrug candidate. Nucleosides, Nucleotides & Nucleic Acids. 22: 699-701. PMID 14565257 DOI: 10.1081/Ncn-120022613 |
0.358 |
|
2003 |
Li P, Dobrikov M, Liu H, Shaw BR. Synthesis of acyclothymidine triphosphate and alpha-P-boranotriphosphate and their substrate properties with retroviral reverse transcriptase. Organic Letters. 5: 2401-3. PMID 12841740 DOI: 10.1021/Ol034538W |
0.53 |
|
2003 |
Dobrikov MI, Grady KM, Shaw BR. Introduction of the alpha-P-borano-group into deoxynucleoside triphosphates increases their selectivity to HIV-1 reverse transcriptase relative to DNA polymerases. Nucleosides, Nucleotides & Nucleic Acids. 22: 275-82. PMID 12816386 DOI: 10.1081/Ncn-120021427 |
0.357 |
|
2002 |
Li P, Shaw BR. Synthesis of nucleoside 3',5'-cyclic boranophosphorothioate, a new type of cyclic nucleotide. Chemical Communications (Cambridge, England). 2890-1. PMID 12478798 DOI: 10.1039/B207350A |
0.357 |
|
2002 |
Li P, Shaw BR. Synthesis of prodrug candidates: conjugates of amino acid with nucleoside boranophosphate. Organic Letters. 4: 2009-12. PMID 12049504 DOI: 10.1021/Ol025832B |
0.372 |
|
2002 |
Fisher AA, Ye D, Sergueev DS, Fisher MH, Shaw BR, Juliano RL. Evaluating the specificity of antisense oligonucleotide conjugates. A DNA array analysis. The Journal of Biological Chemistry. 277: 22980-4. PMID 11948195 DOI: 10.1074/Jbc.M203347200 |
0.341 |
|
2002 |
Lato SM, Ozerova ND, He K, Sergueeva Z, Shaw BR, Burke DH. Boron-containing aptamers to ATP. Nucleic Acids Research. 30: 1401-7. PMID 11884639 DOI: 10.1093/Nar/30.6.1401 |
0.631 |
|
2002 |
Shaw BR, Wan J, Wang X, Dobrikov M, He K, Porter K, Lin J, Rait V, Sergueev D, Sergueeva ZA. Reading and writing genetic information with boranophosphate (borane phosphate) mimics of nucleotides, DNA, and RNA Collection of Czechoslovak Chemical Communications. 5: 169-180. DOI: 10.1135/Css200205169 |
0.723 |
|
2001 |
Sergueev DS, Sergueeva ZA, Shaw BR. Synthesis of oligonucleoside boranophosphates via an H-phosphonate method without nucleobase protection. Nucleosides, Nucleotides & Nucleic Acids. 20: 789-95. PMID 11563117 DOI: 10.1081/Ncn-100002431 |
0.312 |
|
2001 |
Lin J, Shaw BR. Synthesis of new classes of boron-containing nucleotides. Nucleosides, Nucleotides & Nucleic Acids. 20: 587-96. PMID 11563076 DOI: 10.1081/Ncn-100002335 |
0.633 |
|
2001 |
Lin J, Shaw BR. Synthesis of a novel nucleic acid mimic: P-boranomethylphosphonate. Nucleosides, Nucleotides & Nucleic Acids. 20: 1325-8. PMID 11563014 DOI: 10.1081/Ncn-100002547 |
0.64 |
|
2001 |
Lin J, Porter KW, Shaw BR. Synthesis and properties of novel triphosphate analogues: ribonucleoside and deoxyribonucleoside (alpha-P-borano, alpha-P-thio)triphosphates. Nucleosides, Nucleotides & Nucleic Acids. 20: 1019-23. PMID 11562950 DOI: 10.1081/Ncn-100002482 |
0.638 |
|
2001 |
Summers JS, Shaw BR. Boranophosphates as mimics of natural phosphodiesters in DNA. Current Medicinal Chemistry. 8: 1147-55. PMID 11472233 DOI: 10.2174/0929867013372409 |
0.338 |
|
2001 |
He K, Shaw BR. Synthesis and separation of diastereomers of uridine 2',3'-cyclic boranophosphate. Bioorganic & Medicinal Chemistry Letters. 11: 615-7. PMID 11266154 DOI: 10.1016/S0960-894X(00)00700-9 |
0.565 |
|
2001 |
Lin J, He K, Shaw BR. Novel 3',5'-cyclic nucleotide analogue: adenosine 3',5'-cyclic boranomonophosphate. Organic Letters. 3: 795-7. PMID 11263884 DOI: 10.1021/Ol0003230 |
0.705 |
|
2001 |
Lin J, He K, Shaw BR. Novel 3′,5′-cyclic nucleotide analogue: Adenosine 3′,5′-cyclic boranomonophosphate Organic Letters. 3: 795-797. DOI: 10.1021/ol0003230 |
0.496 |
|
2000 |
Astriab-Fisher A, Sergueev DS, Fisher M, Shaw BR, Juliano RL. Antisense inhibition of P-glycoprotein expression using peptide-oligonucleotide conjugates. Biochemical Pharmacology. 60: 83-90. PMID 10807948 DOI: 10.1016/S0006-2952(00)00310-5 |
0.336 |
|
2000 |
Shaw BR, Sergueev D, He K, Porter K, Summers J, Sergueeva Z, Rait V. Boranophosphate backbone: a mimic of phosphodiesters, phosphorothioates, and methyl phosphonates. Methods in Enzymology. 313: 226-57. PMID 10595359 DOI: 10.1016/S0076-6879(00)13015-0 |
0.583 |
|
2000 |
Lin J, Shaw BR. Synthesis of a novel triphosphate analogue: Nucleoside α-P-borano, α-P-thiotriphosphate Chemical Communications. 2115-2116. DOI: 10.1039/B005059H |
0.605 |
|
2000 |
Lin J, Shaw BR. Synthesis of a boron analogue of glucose-conjugated nucleoside diphosphate: Nucleoside α-P-boranodiphosphoglucose Tetrahedron Letters. 41: 6701-6704. DOI: 10.1016/S0040-4039(00)01141-2 |
0.631 |
|
2000 |
Lin J, He K, Shaw BR. Synthesis of boron-containing ADP and GDP analogues: Nucleoside 5'-(Pα- boranodiphosphates) Helvetica Chimica Acta. 83: 1392-1397. DOI: 10.1002/1522-2675(20000705)83:7<1392::Aid-Hlca1392>3.0.Co;2-H |
0.709 |
|
2000 |
Sergueeva ZA, Sergueev DS, Ribeiro AA, Summers JS, Shaw BR. Individual isomers of dinucleoside boranophosphates as synthons for incorporation into oligonucleotides: Synthesis and configurational assignment Helvetica Chimica Acta. 83: 1377-1391. DOI: 10.1002/1522-2675(20000705)83:7<1377::Aid-Hlca1377>3.0.Co;2-S |
0.329 |
|
1999 |
Rait V, Sergueev D, Summers J, He K, Huang F, Krzyzanowska B, Shaw BR. Boranophosphate nucleic acids--a versatile DNA backbone. Nucleosides & Nucleotides. 18: 1379-80. PMID 10474223 DOI: 10.1080/07328319908044721 |
0.585 |
|
1999 |
Rait VK, Shaw BR. Boranophosphates support the RNase H cleavage of polyribonucleotides. Antisense & Nucleic Acid Drug Development. 9: 53-60. PMID 10192289 DOI: 10.1089/Oli.1.1999.9.53 |
0.342 |
|
1999 |
He K, Porter KW, Hasan A, Briley and JD, Shaw BR. Synthesis of 5-substituted 2'-deoxycytidine 5'-(alpha-P-borano)triphosphates, their incorporationinto DNA and effects on exonuclease. Nucleic Acids Research. 27: 1788-94. PMID 10101185 DOI: 10.1093/Nar/27.8.1788 |
0.599 |
|
1999 |
Lin J, Shaw BR. Synthesis and properties of a novel phosphodiester analogue, nucleoside boranophosphorothioate Chemical Communications. 1517-1518. DOI: 10.1039/A901157I |
0.611 |
|
1999 |
He K, Sergueev DS, Sergueeva ZA, Shaw BR. Synthesis of diuridine 3',5'-boranophosphate: H-phosphonate approach Tetrahedron Letters. 40: 4601-4604. DOI: 10.1016/S0040-4039(99)00742-X |
0.573 |
|
1998 |
He K, Hasan A, Krzyzanowska B, Shaw BR. Synthesis and Separation of Diastereomers of Ribonucleoside 5'-(alpha-P-Borano)triphosphates. The Journal of Organic Chemistry. 63: 5769-5773. PMID 11672174 DOI: 10.1021/Jo972002G |
0.617 |
|
1998 |
Sergueev DS, Shaw BR. H-phosphonate approach for solid-phase synthesis of oligodeoxyribonucleoside boranophosphates and their characterization Journal of the American Chemical Society. 120: 9417-9427. DOI: 10.1021/Ja9814927 |
0.322 |
|
1998 |
Krzyzanowska BK, He K, Hasan A, Shaw BR. A convenient synthesis of 2'-deoxyribonucleoside 5'-(α-P- borano)triphosphates Tetrahedron. 54: 5119-5128. DOI: 10.1016/S0040-4020(98)00251-8 |
0.6 |
|
1998 |
He K, Hasan A, Krzyzanowska B, Shaw BR. Synthesis and Separation of Diastereomers of Ribonucleoside 5′-(α-P-Borano)triphosphates Journal of Organic Chemistry. 63: 5769-5773. |
0.523 |
|
1997 |
Sergueev D, Hasan A, Ramaswamy M, Shaw BR. Boranophosphate oligonucleotides: New synthetic approaches Nucleosides and Nucleotides. 16: 1533-1538. DOI: 10.1080/07328319708006223 |
0.335 |
|
1996 |
Hasan A, Li H, Tomasz J, Shaw BR. Base-boronated dinucleotides: synthesis and effect of N7-cyanoborane substitution on the base protons. Nucleic Acids Research. 24: 2150-7. PMID 8668548 DOI: 10.1093/Nar/24.11.2150 |
0.346 |
|
1996 |
Li H, Hardin C, Shaw BR. Hydrolysis of thymidine boranomonophosphate and stepwise deuterium substitution of the borane hydrogens. 31P and 11B NMR studies Journal of the American Chemical Society. 118: 6606-6614. DOI: 10.1021/Ja9540280 |
0.347 |
|
1996 |
Gao Q, Sood A, Shaw BR, Williams LD. 2′-Deoxycytidine-N3-cyanoborane Acta Crystallographica Section C: Crystal Structure Communications. 52: 1823-1825. |
0.428 |
|
1995 |
Porter KW, Tomasz J, Huang F, Sood A, Shaw BR. N7-cyanoborane-2'-deoxyguanosine 5'-triphosphate is a good substrate for DNA polymerase. Biochemistry. 34: 11963-9. PMID 7547933 DOI: 10.1021/Bi00037A038 |
0.322 |
|
1995 |
Li H, Porter K, Huang F, Shaw BR. Boron-containing oligodeoxyribonucleotide 14mer duplexes: enzymatic synthesis and melting studies. Nucleic Acids Research. 23: 4495-501. PMID 7501475 DOI: 10.1093/Nar/23.21.4495 |
0.326 |
|
1992 |
MacPhail RA, Williams LD, Jones DA, Shaw BR. Variable temperature infrared spectroscopy of cytosine-guanine base pairs: tautomerism versus polarization. Journal of Biomolecular Structure & Dynamics. 9: 881-98. PMID 1524704 DOI: 10.1080/07391102.1992.10507964 |
0.526 |
|
1992 |
Tomasz J, Shaw BR, Porter K, Spielvogel BF, Sood A. 5′-P-borane-substituted thymidine monophosphate and triphosphate Angewandte Chemie (International Edition in English). 31: 1373-1375. DOI: 10.1002/Anie.199213731 |
0.365 |
|
1991 |
Spielvogel BF, Sood A, Shaw BR, Hall IH. From boron analogues of amino acids to boronated dna: Potential new pharmaceuticals and neutron capture agents Pure and Applied Chemistry. 63: 415-418. DOI: 10.1351/Pac199163030415 |
0.343 |
|
1990 |
Williams LD, Williams NG, Shaw BR. In a model cytosine:guanine base pair, one amino group rotates and the other does not Journal of the American Chemical Society. 112: 829-833. DOI: 10.1021/Ja00158A050 |
0.501 |
|
1990 |
Williams LD, Williams NG, Shaw BR. In a model C:G base pair, one amino group rotates and the other does not Journal of the American Chemical Society. 112: 829-833. |
0.442 |
|
1989 |
Williams NG, Williams LD, Shaw BR. Dimers, trimers, and tetramers of cytosine with guanine Journal of the American Chemical Society. 111: 7205-7209. DOI: 10.1021/Ja00200A046 |
0.495 |
|
1987 |
Williams LD, Chawla B, Shaw BR. The hydrogen bonding of cytosine with guanine: calorimetric and 1H-nmr analysis of the molecular interactions of nucleic acid bases. Biopolymers. 26: 591-603. PMID 3567328 DOI: 10.1002/Bip.360260411 |
0.511 |
|
1987 |
Williams LD, Shaw BR. Protonated base pairs explain the ambiguous pairing properties of O6-methylguanine. Proceedings of the National Academy of Sciences of the United States of America. 84: 1779-83. PMID 3470757 DOI: 10.1073/Pnas.84.7.1779 |
0.528 |
|
1975 |
Shaw BR, Schurr JM. The association reaction of collagen model polypeptides (Pro‐Pro‐Gly)n Biopolymers. 14: 1951-1985. DOI: 10.1002/Bip.1975.360140913 |
0.517 |
|
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