George Sachs, M.D. - Publications

Affiliations: 
Veteran hospital UCLA Medical School, Los Angeles, CA, United States 
Area:
H+/K+ ATPase

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Year Citation  Score
2019 Cui Y, Zhou K, Strugatsky D, Wen Y, Sachs G, Zhou ZH, Munson K. pH-dependent gating mechanism of the urea channel revealed by cryo-EM. Science Advances. 5: eaav8423. PMID 30906870 DOI: 10.1126/Sciadv.Aav8423  0.326
2018 Wen Y, Scott DR, Vagin O, Tokhtaeva E, Marcus EA, Sachs G. Measurement of Internal pH in by Using Green Fluorescent Protein Fluorimetry. Journal of Bacteriology. PMID 29735759 DOI: 10.1128/Jb.00178-18  0.346
2018 Marcus EA, Sachs G, Scott DR. Acid-regulated gene expression of Helicobacter pylori: Insight into acid protection and gastric colonization. Helicobacter. e12490. PMID 29696729 DOI: 10.1111/Hel.12490  0.42
2017 Abe K, Shimokawa J, Naito M, Munson K, Vagin O, Sachs G, Suzuki H, Tani K, Fujiyoshi Y. The cryo-EM structure of gastric H(+),K(+)-ATPase with bound BYK99, a high-affinity member of K(+)-competitive, imidazo[1,2-a]pyridine inhibitors. Scientific Reports. 7: 6632. PMID 28747707 DOI: 10.1038/S41598-017-06698-8  0.402
2016 Scott DR, Sachs G, Marcus EA. The role of acid inhibition in eradication. F1000research. 5. PMID 30023042 DOI: 10.12688/F1000Research.8598.1  0.383
2016 Habeck M, Tokhtaeva E, Nadav Y, Ben Zeev E, Ferris SP, Kaufman RJ, Bab-Dinitz E, Kaplan JH, Dada LA, Farfel Z, Tal DM, Katz A, Sachs G, Vagin O, Karlish SJ. Selective assembly of Na,K-ATPase α2β2 heterodimers in the heart: distinct functional properties and isoform-selective inhibitors. The Journal of Biological Chemistry. PMID 27624940 DOI: 10.1074/Jbc.M116.751735  0.337
2016 Marcus EA, Sachs G, Scott DR. Eradication of Helicobacter pylori Infection. Current Gastroenterology Reports. 18: 33. PMID 27177639 DOI: 10.1007/S11894-016-0509-X  0.354
2016 Tokhtaeva E, Sun H, Deiss-Yehiely N, Wen Y, Soni PN, Gabrielli NM, Marcus EA, Ridge KM, Sachs G, Vazquez-Levin M, Sznajder JI, Vagin O, Dada LA. FXYD5 O-glycosylated ectodomain impairs adhesion by disrupting cell-cell trans-dimerization of Na,K-ATPase β1 subunits. Journal of Cell Science. PMID 27142834 DOI: 10.1242/Jcs.186148  0.337
2016 Marcus EA, Tokhtaeva E, Turdikulova S, Capri J, Whitelegge JP, Scott DR, Sachs G, Berditchevski F, Vagin O. Septin oligomerization regulates persistent expression of ErbB2/HER2 in gastric cancer cells. The Biochemical Journal. PMID 27048593 DOI: 10.1042/Bcj20160203  0.346
2016 Sachs G, Scott DR. Letter: vonoprazan, a long-lasting acid suppressor of the gastric H+, K+-ATPases with - implications for renal H+, K+-ATPases; authors' reply. Alimentary Pharmacology & Therapeutics. 43: 443. PMID 26782117 DOI: 10.1111/Apt.13487  0.428
2016 Scott DR, Munson KB, Marcus EA, Lambrecht NW, Sachs G. Corrigendum. The binding selectivity of vonoprazan (TAK-438) to the gastric H+,K+-ATPase. Alimentary Pharmacology & Therapeutics. 43: 315. PMID 26741986 DOI: 10.1111/Apt.13493  0.436
2016 Scott DR, Munson KB, Marcus EA, Lambrecht NWG, Sachs G. Eratum: The binding selectivity of vonoprazan (TAK-438) to the gastric H+,K+-ATPase. (Aliment Pharmacol Ther 2015; 42: (1315-26)) Alimentary Pharmacology and Therapeutics. 43: 315. DOI: 10.1111/apt.13493  0.327
2016 Marcus EA, Tokhtaeva E, Scott DR, Naini BV, Sachs G, Vagin O. 146 Helicobacter pylori Infection Decreases Expression of the Na, K-ATPase in Gastric Epithelial Cells, Resulting in Acid-Induced Gastric Injury Gastroenterology. 150. DOI: 10.1016/S0016-5085(16)30247-5  0.45
2015 Scott DR, Munson KB, Marcus EA, Lambrecht NW, Sachs G. The binding selectivity of vonoprazan (TAK-438) to the gastric H(+) ,K(+) -ATPase. Alimentary Pharmacology & Therapeutics. PMID 26423447 DOI: 10.1111/Apt.13414  0.445
2015 Marcus EA, Sachs G, Scott DR. Colloidal bismuth subcitrate impedes proton entry into Helicobacter pylori and increases the efficacy of growth-dependent antibiotics. Alimentary Pharmacology & Therapeutics. 42: 922-33. PMID 26238858 DOI: 10.1111/Apt.13346  0.409
2015 Marcus EA, Sachs G, Wen Y, Scott DR. Phosphorylation-dependent and Phosphorylation-independent Regulation of Helicobacter pylori Acid Acclimation by the ArsRS Two-component System. Helicobacter. PMID 25997502 DOI: 10.1111/Hel.12235  0.398
2015 Marcus EA, Tokhtaeva E, Capri JR, Whitelegge J, Scott DR, Sachs G, Vagin O. Tu1989 Interference With Septin Dynamics Induces ERBB2 Degradation in Gastric Cancer Cells Gastroenterology. 148. DOI: 10.1016/S0016-5085(15)33255-8  0.348
2015 Marcus EA, Sachs G, Scott DR. 693 Colloidal Bismuth Subcitrate (CBS) Raises Internal pH of Helicobacter pylori by Impeding Proton Import, Leading to Increased Metabolism and Increased Efficacy of Growth Dependent Antibiotics Gastroenterology. 148. DOI: 10.1016/S0016-5085(15)30468-6  0.332
2014 Sachs G, Shin JM, Munson K, Scott DR. Gastric acid-dependent diseases: a twentieth-century revolution. Digestive Diseases and Sciences. 59: 1358-69. PMID 24852882 DOI: 10.1007/S10620-014-3104-8  0.384
2014 Marcus EA, Sachs G, Wen Y, Scott DR. 181 Helicobacter pylori ArsR Phosphorylation Regulates Expression of the Urease Gene Cluster and Impacts Acid Acclimation Gastroenterology. 146. DOI: 10.1016/S0016-5085(14)60164-5  0.311
2013 Marcus EA, Vagin O, Tokhtaeva E, Sachs G, Scott DR. Helicobacter pylori impedes acid-induced tightening of gastric epithelial junctions. American Journal of Physiology. Gastrointestinal and Liver Physiology. 305: G731-9. PMID 23989011 DOI: 10.1152/Ajpgi.00209.2013  0.439
2013 Marcus EA, Sachs G, Scott DR. The role of ExbD in periplasmic pH homeostasis in Helicobacter pylori. Helicobacter. 18: 363-72. PMID 23600974 DOI: 10.1111/Hel.12055  0.393
2013 Strugatsky D, McNulty R, Munson K, Chen CK, Soltis SM, Sachs G, Luecke H. Structure of the proton-gated urea channel from the gastric pathogen Helicobacter pylori. Nature. 493: 255-8. PMID 23222544 DOI: 10.1038/Nature11684  0.386
2013 Wen Y, Feng J, Sachs G. Helicobacter pylori 5'ureB-sRNA, a cis-encoded antisense small RNA, negatively regulates ureAB expression by transcription termination. Journal of Bacteriology. 195: 444-52. PMID 23104809 DOI: 10.1128/Jb.01022-12  0.314
2013 Marcus EA, Vagin O, Tokhtaeva E, Sachs G, Scott DR. Sa1889 Helicobacter pylori Infection and Apical Acidity Alter Transepithelial Resistance, Paracellular Permeability, and Inflammatory Response in Gastric Epithelial Cells Gastroenterology. 144. DOI: 10.1016/S0016-5085(13)61199-3  0.396
2012 Marcus EA, Inatomi N, Nagami GT, Sachs G, Scott DR. The effects of varying acidity on Helicobacter pylori growth and the bactericidal efficacy of ampicillin. Alimentary Pharmacology & Therapeutics. 36: 972-9. PMID 23009227 DOI: 10.1111/Apt.12059  0.358
2012 Marcus EA, Sachs G, Wen Y, Feng J, Scott DR. Role of the Helicobacter pylori sensor kinase ArsS in protein trafficking and acid acclimation. Journal of Bacteriology. 194: 5545-51. PMID 22865848 DOI: 10.1128/Jb.01263-12  0.379
2012 Sachs G, Scott DR. Helicobacter pylori: Eradication or Preservation. F1000 Medicine Reports. 4: 7. PMID 22500191 DOI: 10.3410/M4-7  0.343
2012 Vagin O, Dada LA, Tokhtaeva E, Sachs G. The Na-K-ATPase α₁β₁ heterodimer as a cell adhesion molecule in epithelia. American Journal of Physiology. Cell Physiology. 302: C1271-81. PMID 22277755 DOI: 10.1152/Ajpcell.00456.2011  0.38
2012 Marcus EA, Sachs G, Inatomi N, Scott DR. 1045 A Neutral Intragastric pH is Required for Eradication of Helicobacter pylori by Amoxicillin Gastroenterology. 142. DOI: 10.1016/S0016-5085(12)60687-8  0.368
2011 Shin JM, Munson K, Sachs G. Gastric H+,K+-ATPase. Comprehensive Physiology. 1: 2141-53. PMID 23733700 DOI: 10.1002/Cphy.C110010  0.448
2011 Sachs G, Marcus EA, Scott DR. The role of the NMDA receptor in Helicobacter pylori-induced gastric damage. Gastroenterology. 141: 1967-9. PMID 22033182 DOI: 10.1053/J.Gastro.2011.10.019  0.457
2011 Sachs G, Scott DR, Wen Y. Gastric infection by Helicobacter pylori. Current Gastroenterology Reports. 13: 540-6. PMID 21993716 DOI: 10.1007/s11894-011-0226-4  0.31
2011 Shin JM, Inatomi N, Munson K, Strugatsky D, Tokhtaeva E, Vagin O, Sachs G. Characterization of a novel potassium-competitive acid blocker of the gastric H,K-ATPase, 1-[5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine monofumarate (TAK-438). The Journal of Pharmacology and Experimental Therapeutics. 339: 412-20. PMID 21828261 DOI: 10.1124/Jpet.111.185314  0.437
2011 Tokhtaeva E, Sachs G, Souda P, Bassilian S, Whitelegge JP, Shoshani L, Vagin O. Epithelial junctions depend on intercellular trans-interactions between the Na,K-ATPase β₁ subunits. The Journal of Biological Chemistry. 286: 25801-12. PMID 21642423 DOI: 10.1074/Jbc.M111.252247  0.347
2011 Goebel M, Stengel A, Lambrecht NW, Sachs G. Selective gene expression by rat gastric corpus epithelium. Physiological Genomics. 43: 237-54. PMID 21177383 DOI: 10.1152/Physiolgenomics.00193.2010  0.391
2011 Wen Y, Feng J, Scott DR, Marcus EA, Sachs G. A cis-encoded antisense small RNA regulated by the HP0165-HP0166 two-component system controls expression of ureB in Helicobacter pylori. Journal of Bacteriology. 193: 40-51. PMID 20971914 DOI: 10.1128/Jb.00800-10  0.36
2011 Goebel M, Stengel A, Sachs G, Lambrecht NW. Exploration of Selective Gene Expression by Rat Gastric Corpus Epithelium Gastroenterology. 140. DOI: 10.1016/S0016-5085(11)62602-4  0.337
2011 Scott DR, Marcus EA, Wen Y, Feng J, Sachs G. Novel Definition of Helicobacter pylori as a “Gastrophile” Based on Its Requirement for Acid to Maintain Urease Activity, RNA Stability and Bacillary Morphology Gastroenterology. 140. DOI: 10.1016/S0016-5085(11)61930-6  0.33
2011 Sachs G, Scott DR, Feng J, Marcus EA, Wen Y. A Small RNA Determines the up and Down Role of the Hp0165-Hp0166 Two Component System in the Response of Helicobacter pylori to Varying Gastric pH Gastroenterology. 140: S-9. DOI: 10.1016/S0016-5085(11)60040-1  0.373
2011 Marcus EA, Sachs G, Wen Y, Feng J, Scott DR. Protein Trafficking Involving the HP0165/HP0166 Two-Component System (TCS) of Helicobacter pylori Plays an Important Role in Acid Acclimation Gastroenterology. 140. DOI: 10.1016/S0016-5085(11)60039-5  0.348
2011 Shin JM, Munson K, Vagin O, Sachs G. Erratum: The gastric HK-ATPase: structure, function, and inhibition PflüGers Archiv: European Journal of Physiology. 461: 399-399. DOI: 10.1007/S00424-010-0907-0  0.389
2011 Sachs G, Kaunitz J, Mendlein J, Wallmark B. Biochemistry of Gastric Acid Secretion: H+‐K+‐ATPase Comprehensive Physiology. 229-253. DOI: 10.1002/Cphy.Cp060312  0.411
2010 Sachs G, Shin JM, Hunt R. Novel approaches to inhibition of gastric acid secretion. Current Gastroenterology Reports. 12: 437-47. PMID 20924727 DOI: 10.1007/S11894-010-0149-5  0.453
2010 Stengel A, Goebel M, Wang L, Taché Y, Sachs G, Lambrecht NW. Differential distribution of ghrelin-O-acyltransferase (GOAT) immunoreactive cells in the mouse and rat gastric oxyntic mucosa. Biochemical and Biophysical Research Communications. 392: 67-71. PMID 20059966 DOI: 10.1016/J.Bbrc.2009.12.169  0.328
2010 Scott DR, Marcus EA, Wen Y, Singh S, Feng J, Sachs G. Cytoplasmic histidine kinase (HP0244)-regulated assembly of urease with UreI, a channel for urea and its metabolites, CO2, NH3, and NH4(+), is necessary for acid survival of Helicobacter pylori. Journal of Bacteriology. 192: 94-103. PMID 19854893 DOI: 10.1128/Jb.00848-09  0.37
2010 Goebel M, Stengel A, Wang L, Tache Y, Sachs G, Lambrecht NW. W1362 Differential Distribution of Ghrelin-O-Acyltransferase (Goat) Immunoreactive Cells in the Mouse and Rat Gastric Oxyntic Mucosa Gastroenterology. 138. DOI: 10.1016/S0016-5085(10)63253-2  0.334
2010 Shin JM, Munson K, Sachs G. W1103 Mechanism of Inhibition of the Gastric H+,K+-ATPase by a Novel K+-Competitive Acid Blocker Tak-438 Gastroenterology. 138: S-651-S-652. DOI: 10.1016/S0016-5085(10)63000-4  0.451
2010 Sachs G, Shin JM, Hunt R. Erratum to: Novel Approaches to Inhibition of Gastric Acid Secretion Current Gastroenterology Reports. 13: 110-110. DOI: 10.1007/S11894-010-0159-3  0.329
2009 Shin JM, Sachs G. Long lasting inhibitors of the gastric H,K-ATPase. Expert Review of Clinical Pharmacology. 2: 461-468. PMID 21132072 DOI: 10.1586/Ecp.09.33  0.436
2009 Sachs G, Wen Y, Scott DR. Gastric infection by Helicobacter pylori. Current Gastroenterology Reports. 11: 455-61. PMID 19903421 DOI: 10.1007/S11894-009-0070-Y  0.407
2009 Wen Y, Feng J, Scott DR, Marcus EA, Sachs G. The pH-responsive regulon of HP0244 (FlgS), the cytoplasmic histidine kinase of Helicobacter pylori. Journal of Bacteriology. 191: 449-60. PMID 18978046 DOI: 10.1128/Jb.01219-08  0.358
2009 Stengel A, Goebel M, Yakubov I, Wang L, Witcher D, Coskun T, Taché Y, Sachs G, Lambrecht NW. Identification and characterization of nesfatin-1 immunoreactivity in endocrine cell types of the rat gastric oxyntic mucosa. Endocrinology. 150: 232-8. PMID 18818289 DOI: 10.1210/En.2008-0747  0.375
2009 Shin JM, Munson K, Vagin O, Sachs G. The gastric HK-ATPase: structure, function, and inhibition. Pflã¼Gers Archiv : European Journal of Physiology. 457: 609-22. PMID 18536934 DOI: 10.1007/S00424-008-0495-4  0.413
2009 Sachs G, Wen Y, Feng J, Singh S, Marcus EA, Scott DR. 668 Regulation of Urease Membrane Recruitment and Activation By the Cytoplasmic Histidine Kinase, HP0244 of Helicobacter pylori: A Rapid Response to Acidity Gastroenterology. 136: A-103. DOI: 10.1016/S0016-5085(09)60463-7  0.374
2008 Shin JM, Sachs G. Pharmacology of proton pump inhibitors. Current Gastroenterology Reports. 10: 528-34. PMID 19006606 DOI: 10.1007/S11894-008-0098-4  0.414
2008 Law RJ, Munson K, Sachs G, Lightstone FC. An ion gating mechanism of gastric H,K-ATPase based on molecular dynamics simulations. Biophysical Journal. 95: 2739-49. PMID 18567633 DOI: 10.1529/Biophysj.107.128025  0.354
2008 Hunt RH, Armstrong D, Yaghoobi M, James C, Chen Y, Leonard J, Shin JM, Lee E, Tang-Liu D, Sachs G. Predictable prolonged suppression of gastric acidity with a novel proton pump inhibitor, AGN 201904-Z. Alimentary Pharmacology & Therapeutics. 28: 187-99. PMID 18445141 DOI: 10.1111/J.1365-2036.2008.03725.X  0.325
2008 Vagin O, Tokhtaeva E, Yakubov I, Shevchenko E, Sachs G. Inverse correlation between the extent of N-glycan branching and intercellular adhesion in epithelia. Contribution of the Na,K-ATPase beta1 subunit. The Journal of Biological Chemistry. 283: 2192-202. PMID 18025087 DOI: 10.1074/Jbc.M704713200  0.335
2008 Marcus EA, Sachs G, Wen Y, Feng J, Scott DR. 854 The Role of Proton Pump Inhibition in Eradication of Helicobacter pylori Gastroenterology. 134: A-124. DOI: 10.1016/S0016-5085(08)60579-X  0.378
2008 Wen Y, Feng J, Scott DR, Marcus EA, Sachs G. 609 Hp0244 (FLGS) Is An Essential Cytoplasmic pH Sensor for Helicobacter pylori Acid Adaptation Gastroenterology. 134: A-85. DOI: 10.1016/S0016-5085(08)60399-6  0.339
2007 Vagin O, Sachs G, Tokhtaeva E. The roles of the Na,K-ATPase beta 1 subunit in pump sorting and epithelial integrity. Journal of Bioenergetics and Biomembranes. 39: 367-72. PMID 18000747 DOI: 10.1007/S10863-007-9103-0  0.361
2007 Herrmann M, Selige J, Raffael S, Sachs G, Brambilla A, Klein T. Systematic expression profiling of the gastric H+/K+ ATPase in human tissue. Scandinavian Journal of Gastroenterology. 42: 1275-88. PMID 17852870 DOI: 10.1080/00365520701405579  0.429
2007 Sachs G, Shin JM, Vagin O, Lambrecht N, Yakubov I, Munson K. The gastric H,K ATPase as a drug target: past, present, and future. Journal of Clinical Gastroenterology. 41: S226-42. PMID 17575528 DOI: 10.1097/Mcg.0B013E31803233B7  0.446
2007 Lambrecht NW, Yakubov I, Sachs G. Fasting-induced changes in ECL cell gene expression. Physiological Genomics. 31: 183-92. PMID 17536021 DOI: 10.1152/Physiolgenomics.00252.2006  0.411
2007 Scott DR, Marcus EA, Wen Y, Oh J, Sachs G. Gene expression in vivo shows that Helicobacter pylori colonizes an acidic niche on the gastric surface. Proceedings of the National Academy of Sciences of the United States of America. 104: 7235-40. PMID 17438279 DOI: 10.1073/Pnas.0702300104  0.418
2007 Munson K, Law RJ, Sachs G. Analysis of the gastric H,K ATPase for ion pathways and inhibitor binding sites. Biochemistry. 46: 5398-417. PMID 17425287 DOI: 10.1021/Bi062305H  0.391
2007 Wen Y, Feng J, Scott DR, Marcus EA, Sachs G. The HP0165-HP0166 two-component system (ArsRS) regulates acid-induced expression of HP1186 alpha-carbonic anhydrase in Helicobacter pylori by activating the pH-dependent promoter. Journal of Bacteriology. 189: 2426-34. PMID 17220228 DOI: 10.1128/Jb.01492-06  0.344
2006 Sachs G, Kraut JA, Wen Y, Feng J, Scott DR. Urea transport in bacteria: acid acclimation by gastric Helicobacter spp. The Journal of Membrane Biology. 212: 71-82. PMID 17264989 DOI: 10.1007/s00232-006-0867-7  0.358
2006 Vagin O, Tokhtaeva E, Sachs G. The role of the beta1 subunit of the Na,K-ATPase and its glycosylation in cell-cell adhesion. The Journal of Biological Chemistry. 281: 39573-87. PMID 17052981 DOI: 10.1074/Jbc.M606507200  0.348
2006 Sachs G, Shin JM, Howden CW. Review article: the clinical pharmacology of proton pump inhibitors. Alimentary Pharmacology & Therapeutics. 23: 2-8. PMID 16700898 DOI: 10.1111/J.1365-2036.2006.02943.X  0.396
2006 Shin JM, Sachs G. Gastric H,K-ATPase as a drug target. Digestive Diseases and Sciences. 51: 823-33. PMID 16645899 DOI: 10.1007/S10620-005-9042-8  0.413
2006 Wen Y, Feng J, Scott DR, Marcus EA, Sachs G. Involvement of the HP0165-HP0166 two-component system in expression of some acidic-pH-upregulated genes of Helicobacter pylori. Journal of Bacteriology. 188: 1750-61. PMID 16484186 DOI: 10.1128/Jb.188.5.1750-1761.2006  0.326
2006 Shin JM, Homerin M, Domagala F, Ficheux H, Sachs G. Characterization of the inhibitory activity of tenatoprazole on the gastric H+,K+ -ATPase in vitro and in vivo. Biochemical Pharmacology. 71: 837-49. PMID 16405921 DOI: 10.1016/J.Bcp.2005.11.030  0.459
2006 Lambrecht NW, Yakubov I, Zer C, Sachs G. Transcriptomes of purified gastric ECL and parietal cells: identification of a novel pathway regulating acid secretion. Physiological Genomics. 25: 153-65. PMID 16403840 DOI: 10.1152/Physiolgenomics.00271.2005  0.386
2006 Sefton J, Parizadeh D, Lee E, Li H, Euler A, Morelli G, Sachs G, Tang-Liu D. A Novel Next-Generation Proton Pump Inhibitor (AGN 201904-Z) with a Long Plasma Residence Time Provides More Prolonged Gastric Acid Inhibition Than Esomeprazole: 124 The American Journal of Gastroenterology. 101. DOI: 10.14309/00000434-200609001-00124  0.373
2005 Shin JM, Grundler G, Senn-Bilfinger J, Simon WA, Sachs G. Functional consequences of the oligomeric form of the membrane-bound gastric H,K-ATPase. Biochemistry. 44: 16321-32. PMID 16331993 DOI: 10.1021/Bi051342Q  0.358
2005 Sachs G, Weeks DL, Wen Y, Marcus EA, Scott DR, Melchers K. Acid acclimation by Helicobacter pylori. Physiology (Bethesda, Md.). 20: 429-38. PMID 16287992 DOI: 10.1152/Physiol.00032.2005  0.419
2005 Saccomani G, Stewart HB, Shaw D, Lewin M, Sachs G. Characterization of gastric mucosal membranes. IX. Fractionation and purification of K+-ATPase-containing vesicles by zonal centrifugation and free-flow electrophoresis technique. Biochimica Et Biophysica Acta. 465: 311-30. PMID 16250342 DOI: 10.1016/0005-2736(77)90081-5  0.393
2005 Vagin O, Turdikulova S, Sachs G. Recombinant addition of N-glycosylation sites to the basolateral Na,K-ATPase beta1 subunit results in its clustering in caveolae and apical sorting in HGT-1 cells. The Journal of Biological Chemistry. 280: 43159-67. PMID 16230337 DOI: 10.1074/Jbc.M508262200  0.323
2005 Mareninova O, Shin JM, Vagin O, Turdikulova S, Hallen S, Sachs G. Topography of the membrane domain of the liver Na+-dependent bile acid transporter. Biochemistry. 44: 13702-12. PMID 16229460 DOI: 10.1021/Bi051291X  0.35
2005 Oh DS, Lieu SN, Yamaguchi DJ, Tachiki K, Lambrecht N, Ohning GV, Sachs G, Germano PM, Pisegna JR. PACAP regulation of secretion and proliferation of pure populations of gastric ECL cells. Journal of Molecular Neuroscience : Mn. 26: 85-97. PMID 15968088 DOI: 10.1385/Jmn:26:1:085  0.374
2005 Munson K, Garcia R, Sachs G. Inhibitor and ion binding sites on the gastric H,K-ATPase. Biochemistry. 44: 5267-84. PMID 15807521 DOI: 10.1021/Bi047761P  0.373
2005 Diller A, Vagin O, Sachs G, Apell HJ. Electrogenic partial reactions of the gastric H,K-ATPase. Biophysical Journal. 88: 3348-59. PMID 15749775 DOI: 10.1529/Biophysj.104.055913  0.406
2005 Vagin O, Turdikulova S, Yakubov I, Sachs G. Use of the H,K-ATPase beta subunit to identify multiple sorting pathways for plasma membrane delivery in polarized cells. The Journal of Biological Chemistry. 280: 14741-54. PMID 15695513 DOI: 10.1074/Jbc.M412657200  0.374
2005 Marcus EA, Moshfegh AP, Sachs G, Scott DR. The periplasmic alpha-carbonic anhydrase activity of Helicobacter pylori is essential for acid acclimation. Journal of Bacteriology. 187: 729-38. PMID 15629943 DOI: 10.1128/Jb.187.2.729-738.2005  0.334
2005 Lambrecht NW, Yakubov I, Scott D, Sachs G. Identification of the K efflux channel coupled to the gastric H-K-ATPase during acid secretion. Physiological Genomics. 21: 81-91. PMID 15613615 DOI: 10.1152/Physiolgenomics.00212.2004  0.449
2005 Shin JM, Sachs G. CorrigendumCorrigendum to “Differences in binding properties of two proton pump inhibitors on the gastric H+, K+-ATPase in vivo” [Biochemical Pharmacology 68 (11) (2004) 2117–2127] Biochemical Pharmacology. 70: 648. DOI: 10.1016/J.Bcp.2005.05.006  0.447
2004 Shin JM, Sachs G. Differences in binding properties of two proton pump inhibitors on the gastric H+,K+-ATPase in vivo. Biochemical Pharmacology. 68: 2117-27. PMID 15498502 DOI: 10.1016/J.Bcp.2004.07.035  0.409
2004 Vagin O, Turdikulova S, Sachs G. The H,K-ATPase beta subunit as a model to study the role of N-glycosylation in membrane trafficking and apical sorting. The Journal of Biological Chemistry. 279: 39026-34. PMID 15247221 DOI: 10.1074/Jbc.M405453200  0.314
2004 Shin JM, Cho YM, Sachs G. Chemistry of covalent inhibition of the gastric (H+, K+)-ATPase by proton pump inhibitors. Journal of the American Chemical Society. 126: 7800-11. PMID 15212527 DOI: 10.1021/ja049607w  0.306
2004 Kim N, Marcus EA, Wen Y, Weeks DL, Scott DR, Jung HC, Song IS, Sachs G. Genes of Helicobacter pylori regulated by attachment to AGS cells. Infection and Immunity. 72: 2358-68. PMID 15039361 DOI: 10.1128/Iai.72.4.2358-2368.2004  0.393
2004 Weeks DL, Gushansky G, Scott DR, Sachs G. Mechanism of proton gating of a urea channel. The Journal of Biological Chemistry. 279: 9944-50. PMID 14701805 DOI: 10.1074/Jbc.M312680200  0.358
2003 Sachs G. Physiology of the parietal cell and therapeutic implications. Pharmacotherapy. 23: 68S-73S. PMID 14587960 DOI: 10.1592/Phco.23.13.68S.31931  0.448
2003 Wen Y, Marcus EA, Matrubutham U, Gleeson MA, Scott DR, Sachs G. Acid-adaptive genes of Helicobacter pylori. Infection and Immunity. 71: 5921-39. PMID 14500513 DOI: 10.1128/Iai.71.10.5921-5939.2003  0.367
2003 Pantoflickova D, Scott DR, Sachs G, Dorta G, Blum AL. 13C urea breath test (UBT) in the diagnosis of Helicobacter pylori: Why does it work better with acid test meals? Gut. 52: 933-937. PMID 12801946 DOI: 10.1136/Gut.52.7.933  0.408
2003 Vagin O, Denevich S, Sachs G. Plasma membrane delivery of the gastric H,K-ATPase: The role of β-subunit glycosylation American Journal of Physiology - Cell Physiology. 285: C968-C976. PMID 12773316 DOI: 10.1152/Ajpcell.00068.2003  0.38
2003 Vagin O, Munson K, Denevich S, Sachs G. Inhibition kinetics of the gastric H,K-ATPase by K-competitive inhibitor SCH28080 as a tool for investigating the luminal ion pathway. Annals of the New York Academy of Sciences. 986: 111-5. PMID 12763783 DOI: 10.1111/J.1749-6632.2003.Tb07147.X  0.38
2003 Munson K, Vagin O, Sachs G, Karlish S. Molecular modeling of SCH28080 binding to the gastric H,K-ATPase and MgATP interactions with SERCA- and Na,K-ATPases. Annals of the New York Academy of Sciences. 986: 106-10. PMID 12763782 DOI: 10.1111/J.1749-6632.2003.Tb07146.X  0.372
2003 Hong W, Sano K, Morimatsu S, Scott DR, Weeks DL, Sachs G, Goto T, Mohan S, Harada F, Nakajima N, Nakano T. Medium pH-dependent redistribution of the urease of Helicobacter pylori. Journal of Medical Microbiology. 52: 211-6. PMID 12621085 DOI: 10.1099/Jmm.0.05072-0  0.43
2003 Tatishchev S, Abuladze N, Pushkin A, Newman D, Liu W, Weeks D, Sachs G, Kurtz I. Identification of membrane topography of the electrogenic sodium bicarbonate cotransporter pNBC1 by in vitro transcription/translation. Biochemistry. 42: 755-65. PMID 12534288 DOI: 10.1021/Bi026826Q  0.364
2003 Sachs G, Weeks DL, Melchers K, Scott DR. The gastric biology of Helicobacter pylori. Annual Review of Physiology. 65: 349-69. PMID 12471160 DOI: 10.1146/Annurev.Physiol.65.092101.142156  0.448
2003 Voland P, Weeks DL, Marcus EA, Prinz C, Sachs G, Scott D. Interactions among the seven Helicobacter pylori proteins encoded by the urease gene cluster. American Journal of Physiology. Gastrointestinal and Liver Physiology. 284: G96-G106. PMID 12388207 DOI: 10.1152/Ajpgi.00160.2002  0.377
2003 Yuan P, Wu SV, Scott DR, Sachs G, Ohning GV. Differential expression of two alternative spliced variants of fibroblast growth factor receptor 2 (FGFR2) in gastric fundus of rats Gastroenterology. 124. DOI: 10.1016/S0016-5085(03)82376-4  0.318
2003 Shin JM, Sachs G. Biochemical reversal of proton pump inhibition in vivo Gastroenterology. 124. DOI: 10.1016/S0016-5085(03)82243-6  0.392
2003 Wen Y, Marcus EA, Scott DR, Sachs G. Expression profiling of responses of Helicobacter pylori to acidic media Gastroenterology. 124. DOI: 10.1016/S0016-5085(03)81358-6  0.349
2003 Kim N, Wen Y, Weeks DL, Scott DR, Sachs G. Cell adhesion induced gene expression in Helicobacter pylori Gastroenterology. 124. DOI: 10.1016/S0016-5085(03)80257-3  0.332
2002 Mollenhauer-Rektorschek M, Hanauer G, Sachs G, Melchers K. Expression of UreI is required for intragastric transit and colonization of gerbil gastric mucosa by Helicobacter pylori. Research in Microbiology. 153: 659-66. PMID 12558185 DOI: 10.1016/S0923-2508(02)01380-3  0.435
2002 Sachs G, Shin JM, Vagin O, Munson K, Weeks D, Scott DR, Voland P. Current trends in the treatment of upper gastrointestinal disease. Best Practice & Research. Clinical Gastroenterology. 16: 835-49. PMID 12473294 DOI: 10.1053/Bega.2002.0338  0.38
2002 Shin JM, Sachs G. Restoration of acid secretion following treatment with proton pump inhibitors. Gastroenterology. 123: 1588-97. PMID 12404233 DOI: 10.1053/Gast.2002.36593  0.419
2002 Kim N, Weeks DL, Shin JM, Scott DR, Young MK, Sachs G. Proteins released by Helicobacter pylori in vitro. Journal of Bacteriology. 184: 6155-62. PMID 12399485 DOI: 10.1128/Jb.184.22.6155-6162.2002  0.343
2002 Scott DR, Marcus EA, Weeks DL, Sachs G. Mechanisms of acid resistance due to the urease system of Helicobacter pylori. Gastroenterology. 123: 187-95. PMID 12105847 DOI: 10.1053/Gast.2002.34218  0.39
2002 Sachs G, Scott D, Weeks D, Melchers K. The compartment buffered by the urease of Helicobacter pylori: cytoplasm or periplasm? Trends in Microbiology. 10: 217-8; author reply . PMID 11973151 DOI: 10.1016/S0966-842X(02)02346-6  0.414
2002 Voland P, Weeks DL, Vaira D, Prinz C, Sachs G. Specific identification of three low molecular weight membrane-associated antigens of Helicobacter pylori Alimentary Pharmacology and Therapeutics. 16: 533-544. PMID 11876708 DOI: 10.1046/J.1365-2036.2002.01221.X  0.318
2001 Ha NC, Oh BH, Sachs G, Scott D, Weeks D, Melchers K. The importance of the surface urease of Helicobacter pylori: Fact fiction? [2] (multiple letters) Trends in Microbiology. 9: 532-534. PMID 11825711 DOI: 10.1016/S0966-842X(01)02226-0  0.327
2001 Wolfe MM, Welage LS, Sachs G. Proton pump inhibitors and gastric acid secretion [23] American Journal of Gastroenterology. 96: 3467-3468. PMID 11774990 DOI: 10.1111/j.1572-0241.2001.05362.x  0.3
2001 Shin JM, Goldshleger R, Munson KB, Sachs G, Karlish SJD. Selective Fe2+-catalyzed Oxidative Cleavage of Gastric H +,K+-ATPase: Implications for the Energy Transduction Mechanism of P-type Cation Pumps Journal of Biological Chemistry. 276: 48440-48450. PMID 11585827 DOI: 10.1074/Jbc.M106864200  0.369
2001 Kraut JA, Helander KG, Helander HF, Iroezi ND, Marcus EA, Sachs G. Detection and localization of H+-K+-ATPase isoforms in human kidney. American Journal of Physiology. Renal Physiology. 281: F763-8. PMID 11553523 DOI: 10.1152/Ajprenal.2001.281.4.F763  0.358
2001 Weeks DL, Sachs G. Sites of PH regulation of the urea channel of Helicobacter pylori Molecular Microbiology. 40: 1249-1259. PMID 11442825 DOI: 10.1046/J.1365-2958.2001.02466.X  0.356
2001 Vagin O, Munson K, Lambrecht N, Karlish SJD, Sachs G. Mutational analysis of the K+-competitive inhibitor site of gastric H,K-ATPase Biochemistry. 40: 7480-7490. PMID 11412101 DOI: 10.1021/Bi0105328  0.395
2001 Bell N, Karol MD, Sachs G, Greski-Rose P, Jennings DE, Hunt RH. Duration of effect of lansoprazole on gastric pH and acid secretion in normal male volunteers Alimentary Pharmacology and Therapeutics. 15: 105-113. PMID 11136283 DOI: 10.1046/J.1365-2036.2001.00831.X  0.365
2001 Sachs G. Identification of the periplasmic amino acids involved in H+gating of urea uptake via Helicobacter pylori urel Gastroenterology. 120: A514. DOI: 10.1016/S0016-5085(08)82550-4  0.4
2001 Vagin O, Munson K, Lambrecht N, Sachs G. The binding region of a novel class of anti-ulcer drugs, the imidazo[1,2 alpha] pyridines, on the gastric H,K-ATPase Gastroenterology. 120: A102. DOI: 10.1016/S0016-5085(08)80501-X  0.399
2001 Kim N, Weeks DL, Shin JM, Scott DR, Sachs G. Possible pathogenic proteins of H. pylori identified by in vitro secretion analysis Gastroenterology. 120. DOI: 10.1016/S0016-5085(08)80273-9  0.351
2001 Hanauer G, Hermann L, Rektorschek M, Postius S, Sachs G, Melchers K. Urel-encoded urea channel of Helicobacter pylori is essential for both gastric colonization of and persistence in gerbils Gastroenterology. 120. DOI: 10.1016/S0016-5085(08)80272-7  0.402
2001 Wolfe MM, Welage LS, Sachs G. Proton pump inhibitors and gastric acid secretion. The American Journal of Gastroenterology. 96: 3467-3468. DOI: 10.1016/S0002-9270(01)03924-7  0.415
2000 Pisegna JR, Ohning GV, Athmann C, Zeng N, Walsh JH, Sachs G. Role of PACAP1 receptor in regulation of ECL cells and gastric acid secretion by pituitary adenylate cyclase activating peptide. Annals of the New York Academy of Sciences. 921: 233-41. PMID 11193828 DOI: 10.1111/J.1749-6632.2000.Tb06971.X  0.418
2000 Sachs G, Scott D, Weeks D, Melchers K. Gastric habitation by Helicobacter pylori: Insights into acid adaptation Trends in Pharmacological Sciences. 21: 413-416. PMID 11121568 DOI: 10.1016/S0165-6147(00)01554-6  0.41
2000 Sachs G, Shin JM, Munson K, Vagin O, Lambrecht N, Scott DR, Weeks DL, Melchers K. Review article: The control of gastric acid and Helicobacter pylori eradication Alimentary Pharmacology and Therapeutics. 14: 1383-1401. PMID 11069309 DOI: 10.1046/J.1365-2036.2000.00837.X  0.428
2000 Athmann C, Zeng N, Scott DR, Sachs G. Regulation of parietal cell calcium signaling in gastric glands American Journal of Physiology - Gastrointestinal and Liver Physiology. 279: G1048-G1058. PMID 11053003 DOI: 10.1152/Ajpgi.2000.279.5.G1048  0.335
2000 Hong W, Morimatsu S, Goto T, Sachs G, Scott DR, Weeks DL, Kohno T, Morita C, Nakano T, Fujioka Y, Sano K. Contrast-enhanced immunoelectron microscopy for Helicobacter pylori Journal of Microbiological Methods. 42: 121-127. PMID 11018268 DOI: 10.1016/S0167-7012(00)00165-2  0.325
2000 Athmann C, Zeng N, Kang T, Marcus EA, Scott DR, Rektorschek M, Buhmann A, Melchers K, Sachs G. Local pH elevation mediated by the intrabacterial urease of Helicobacter pylori cocultured with gastric cells Journal of Clinical Investigation. 106: 339-347. PMID 10930437 DOI: 10.1172/Jci9351  0.388
2000 Scott D, Weeks D, Melchers K, Sachs G. UreI-mediated urea transport in Helicobacter pylori: An open and shut case? Response Trends in Microbiology. 8: 348-349. PMID 10920391 DOI: 10.1016/S0966-842X(00)01815-1  0.332
2000 Zizak M, Cavet ME, Bayle D, Tse CM, Hallen S, Sachs G, Donowitz M. Na(+)/H(+) exchanger NHE3 has 11 membrane spanning domains and a cleaved signal peptide: topology analysis using in vitro transcription/translation. Biochemistry. 39: 8102-12. PMID 10891093 DOI: 10.1021/Bi000870T  0.34
2000 Hallén S, Fryklund J, Sachs G. Inhibition of the human sodium/bile acid cotransporters by side-specific methanethiosulfonate sulfhydryl reagents: Substrate-controlled accessibility of site of inactivation Biochemistry. 39: 6743-6750. PMID 10828993 DOI: 10.1021/Bi000577T  0.337
2000 Rektorschek M, Buhmann A, Weeks D, Schwan D, Bensch KW, Eskandari S, Scott D, Sachs G, Melchers K. Acid resistance of Helicobacter pylori depends on the UreI membrane protein and an inner membrane proton barrier. Molecular Microbiology. 36: 141-52. PMID 10760171 DOI: 10.1046/J.1365-2958.2000.01835.X  0.418
2000 Munson KB, Lambrecht N, Sachs G. Effects of mutations in M4 of the gastric H+,K+-ATPase on inhibition kinetics of SCH28080. Biochemistry. 39: 2997-3004. PMID 10715120 DOI: 10.1021/Bi991837D  0.444
2000 Lambrecht N, Munson K, Vagin O, Sachs G. Comparison of covalent with reversible inhibitor binding sites of the gastric H,K-ATPase by site-directed mutagenesis. The Journal of Biological Chemistry. 275: 4041-8. PMID 10660561 DOI: 10.1074/Jbc.275.6.4041  0.416
2000 Weeks DL, Eskandari S, Scott DR, Sachs G. A H+-gated urea channel: the link between Helicobacter pylori urease and gastric colonization. Science (New York, N.Y.). 287: 482-5. PMID 10642549 DOI: 10.1126/Science.287.5452.482  0.476
2000 Scott DR, Marcus EA, Weeks DL, Lee A, Melchers K, Sachs G. Expression of the Helicobacter pylori ureI gene is required for acidic pH activation of cytoplasmic urease. Infection and Immunity. 68: 470-7. PMID 10639406 DOI: 10.1128/Iai.68.2.470-477.2000  0.422
2000 Pisegna JR, Miampamba M, Germano PM, Walsh JH, Hannibal J, Fahrenkrug J, Wong H, Sachs G. Immunohistochemical localization of PACAP and its receptor, PAC1, in the gastric and colonic enteric nervous system Regulatory Peptides. 94: 33. DOI: 10.1016/S0167-0115(00)80067-1  0.359
2000 Lambrecht N, Munson KB, Vagin O, Sachs G. Investigation of the SCH28080 binding site in the gastric H,K atpase Gastroenterology. 118: A888. DOI: 10.1016/S0016-5085(00)85691-7  0.43
2000 Voland PR, Sachs G. Identification of the interaction of UREG/UREE and UREF/UREH in H. pylori using a yeast two-hybrid screen Gastroenterology. 118. DOI: 10.1016/S0016-5085(00)85076-3  0.304
2000 Scott DR, Marcus EA, Sachs G. The effect of L-arginine on H. pylori bioenergetics and viability Gastroenterology. 118. DOI: 10.1016/S0016-5085(00)85066-0  0.32
2000 Weeks DL, Scott DR, Eskandari S, Marcus EA, Kim N, Rektorschek M, Buhmann A, Schmitt B, Melchers K, Sachs G. Urei is the link between intra-bacterial urease of Helicobacter pylori and gastric survival Gastroenterology. 118. DOI: 10.1016/S0016-5085(00)84856-8  0.357
2000 Pantoflickova D, Lew EA, Dorta G, Pisegna JR, Ohning GV, Faller LV, Scott D, Walsh JH, Sachs G, Blum AL. Intragastric pH affects the results of the 13C-urea breath test (UBT) in the diagnosis of H. pylori (Hp) Gastroenterology. 118. DOI: 10.1016/S0016-5085(00)84152-9  0.333
2000 Miampamba M, Germano PM, Tache Y, Fahrenkrug JA, Hannibal J, Wong H, Walsh JH, Scott D, Sachs G, Pisegna JR. Immunohistochemical assessment of PACAP and its receptor PAC1 in the gastric and colonic enteric nervous system in rat Gastroenterology. 118: A307. DOI: 10.1016/S0016-5085(00)83316-8  0.346
2000 Lambrecht N, Munson KB, Vagin O, Shin JM, Simon A, Senn-Bilfinger J, Sachs G. The drug target regions of the gastric H,K ATPase Gastroenterology. 118: A30. DOI: 10.1016/S0016-5085(00)82189-7  0.409
1999 Zeng N, Athmann C, Kang T, Walsh JH, Sachs G. Role of neuropeptide-sensitive L-type Ca(2+) channels in histamine release in gastric enterochromaffin-like cells. The American Journal of Physiology. 277: G1268-80. PMID 10600825 DOI: 10.1152/Ajpgi.1999.277.6.G1268  0.348
1999 Zeng N, Athmann C, Kang T, Lyu RM, Walsh JH, Ohning GV, Sachs G, Pisegna JR. PACAP type I receptor activation regulates ECL cells and gastric acid secretion. The Journal of Clinical Investigation. 104: 1383-91. PMID 10562300 DOI: 10.1172/Jci7537  0.403
1999 Hallén S, Brändén M, Dawson PA, Sachs G. Membrane insertion scanning of the human ileal sodium/bile acid co-transporter. Biochemistry. 38: 11379-88. PMID 10471288 DOI: 10.1021/Bi990554I  0.333
1999 Beggah AT, Béguin P, Bamberg K, Sachs G, Geering K. β-Subunit Assembly Is Essential for the Correct Packing and the Stable Membrane Insertion of the H,K-ATPase α-Subunit Journal of Biological Chemistry. 274: 8217-8223. PMID 10075726 DOI: 10.1074/Jbc.274.12.8217  0.308
1998 Zeng N, Kang T, Lyu RM, Wong H, Wen Y, Walsh JH, Sachs G, Pisegna JR. The pituitary adenylate cyclase activating polypeptide type 1 receptor (PAC1-R) is expressed on gastric ECL cells: evidence by immunocytochemistry and RT-PCR. Annals of the New York Academy of Sciences. 865: 147-56. PMID 9928007 DOI: 10.1111/J.1749-6632.1998.Tb11173.X  0.34
1998 Scott D, Weeks D, Melchers K, Sachs G. The life and death of Helicobacter pylori Gut. 43. PMID 9764042 DOI: 10.1136/Gut.43.2008.S56  0.387
1998 Rektorschek M, Weeks D, Sachs G, Melchers K. Influence of pH on metabolism and urease activity of Helicobacter pylori. Gastroenterology. 115: 628-41. PMID 9721160 DOI: 10.1016/S0016-5085(98)70142-8  0.388
1998 Zeng N, Kang T, Wen Y, Wong H, Walsh J, Sachs G. Galanin inhibition of enterochromaffin-like cell function. Gastroenterology. 115: 330-9. PMID 9679038 DOI: 10.1016/S0016-5085(98)70199-4  0.386
1998 Lambrecht N, Corbett Z, Bayle D, Karlish SJ, Sachs G. Identification of the site of inhibition by omeprazole of a alpha-beta fusion protein of the H,K-ATPase using site-directed mutagenesis. The Journal of Biological Chemistry. 273: 13719-28. PMID 9593713 DOI: 10.1074/Jbc.273.22.13719  0.44
1998 Melle-Milovanovic D, Milovanovic M, Nagpal S, Sachs G, Shin JM. Regions of association between the alpha and the beta subunit of the gastric H,K-ATPase. The Journal of Biological Chemistry. 273: 11075-81. PMID 9556592 DOI: 10.1074/Jbc.273.18.11075  0.321
1998 Scott DR, Weeks D, Hong C, Postius S, Melchers K, Sachs G. The role of internal urease in acid resistance of Helicobacter pylori. Gastroenterology. 114: 58-70. PMID 9428219 DOI: 10.1016/S0016-5085(98)70633-X  0.361
1998 Bayle D, Wängler S, Weitzenegger T, Steinhilber W, Volz J, Przybylski M, Schäfer KP, Sachs G, Melchers K. Properties of the P-Type ATPases Encoded by the copAPOperons of Helicobacter pylori andHelicobacter felis Journal of Bacteriology. 180: 317-329. DOI: 10.1128/Jb.180.2.317-329.1998  0.378
1998 Zeng N, Kang T, Lyu R, Ohning G, Wang Y, Walsh J, Sachs G, Pisegna J. Pituitary adenylate cyclase activating peptide (PACAP): A neuropeptide that stimulates gastric acid secretion Gastroenterology. 114. DOI: 10.1016/S0016-5085(98)84858-0  0.366
1998 Zeng N, Kang T, Athmann C, Wen Y, Walsh J, Sachs G. Identification of gastric endocrine cells as the target sites of neuropeptides in regulation of gastric secretion by semi-quantitative RT-PCR and video imaging Gastroenterology. 114. DOI: 10.1016/S0016-5085(98)84857-9  0.376
1998 Ohning GV, Curi A, Lyu RM, Zeng N, Wong HC, Sachs G, Walsh JH, Pisegna JR. PACAP stimulates gastric acid secretion during somatostatin immunoneutralization in rats Gastroenterology. 114. DOI: 10.1016/S0016-5085(98)84758-6  0.385
1998 Voland P, Hiura J, Scott D, Varia D, Sachs G. Human sera from Helicobacter pylori infected patients inhibits Helicobacter pylori motility in vitro Gastroenterology. 114: A1111. DOI: 10.1016/S0016-5085(98)84516-2  0.348
1998 Scott DR, Weeks D, Sachs G, Rektorschek M, Schafer KP, Melchers K. Acid regulation of internal urease of Helicobacter pylori is essential for gastric colonization Gastroenterology. 114: A1082. DOI: 10.1016/S0016-5085(98)84400-4  0.42
1998 Zeng N, Athmann C, Yang H, Kang T, Scott D, Voland P, Helander H, Walsh J, Sachs G. Characterization of a ph-sensitive, ip3independent calcium store in gastric tumor (AGS) cells as a possible link between h. Pylori infection and functional alteration of the gastric epithelium Gastroenterology. 114. DOI: 10.1016/S0016-5085(98)81399-1  0.407
1998 Lambrecht N, Corbett Z, Bayle D, Karlish S, Sachs G. Identification of the loop region between TM5 and TM6 of the H,K ATPase using cysteine mutagenesis Gastroenterology. 114: A194. DOI: 10.1016/S0016-5085(98)80788-9  0.343
1997 Shin JM, Besancon M, Bamberg K, Sachs G. Structural Aspects of the Gastric H, K ATPasea Annals of the New York Academy of Sciences. 834: 65-76. PMID 9405786 DOI: 10.1111/J.1749-6632.1997.Tb52226.X  0.385
1997 Besancon M, Simon A, Sachs G, Shin JM. Sites of reaction of the gastric H,K-ATPase with extracytoplasmic thiol reagents. The Journal of Biological Chemistry. 272: 22438-46. PMID 9278394 DOI: 10.1074/Jbc.272.36.22438  0.452
1997 Bayle D, Weeks D, Sachs G. Identification of membrane insertion sequences of the rabbit gastric cholecystokinin-A receptor by in vitro translation. The Journal of Biological Chemistry. 272: 19697-707. PMID 9242625 DOI: 10.1074/Jbc.272.32.19697  0.381
1997 Sachs G, Meyer-Rosberg K, Scott DR, Melchers K, Shin J, Besancon M. Acid secretion and Helicobacter pylori. Digestion. 8-13. PMID 9225081 DOI: 10.1159/000201514  0.402
1997 Sachs G, Zeng N, Prinz C. Physiology of isolated gastric endocrine cells Annual Review of Physiology. 59: 243-256. PMID 9074763 DOI: 10.1146/Annurev.Physiol.59.1.243  0.377
1997 Zeng N, Walsh JH, Kang T, Wu SV, Sachs G. Peptide YY inhibition of rat gastric enterochromaffin-like cell function. Gastroenterology. 112: 127-35. PMID 8978351 DOI: 10.1016/S0016-5085(97)70227-0  0.379
1997 Shin JM, Bayle D, Bamberg K, Sachs G. The Gastric H+-K+-ATPase Advances in Molecular and Cell Biology. 23. DOI: 10.1016/S1569-2558(08)60153-8  0.454
1997 Sachs G. Proton pump inhibitors and acid-related diseases. Pharmacotherapy. 17: 22-37. DOI: 10.1002/J.1875-9114.1997.Tb03675.X  0.421
1996 Loo DD, Sachs G, Prinz C. Potassium and chloride currents in rat gastric enterochromaffin-like cells. The American Journal of Physiology. 270: E739-45. PMID 8967460 DOI: 10.1152/Ajpgi.1996.270.5.G739  0.426
1996 Zeng N, Walsh JH, Kang T, Helander KG, Helander HF, Sachs G. Selective ligand-induced intracellular calcium changes in a population of rat isolated gastric endocrine cells. Gastroenterology. 110: 1835-46. PMID 8964409 DOI: 10.1053/Gast.1996.V110.Pm8964409  0.358
1996 Meyer-Rosberg K, Scott, Rex D, Melchers K, Sachs G. The effect of environmental pH on the proton motive force of Helicobacter pylori Gastroenterology. 111: 886-900. PMID 8831583 DOI: 10.1016/S0016-5085(96)70056-2  0.329
1996 Helander KG, Bamberg K, Sachs G, Melle D, Helander HF. Localization of mRNA for the muscarinic M1 receptor in rat stomach. Biochimica Et Biophysica Acta. 1312: 158-62. PMID 8672539 DOI: 10.1016/0167-4889(96)00021-3  0.304
1996 Shin JM, Sachs G. Dimerization of the Gastric H,K-ATPase Journal of Biological Chemistry. 271: 1904-1908. PMID 8567637 DOI: 10.1074/Jbc.271.4.1904  0.391
1996 Melchers K, Weitzenegger T, Buhmann A, Steinhilber W, Sachs G, Schäfer KP. Cloning and membrane topology of a P type ATPase from Helicobacter pylori. The Journal of Biological Chemistry. 271: 446-57. PMID 8550601 DOI: 10.1074/Jbc.271.1.446  0.383
1996 Huber R, Kohl B, Sachs G, Senn-Bilfinger J, Simon WA, Sturm E. Review article: the continuing development of proton pump inhibitors with particular reference to pantoprazole. Alimentary Pharmacology & Therapeutics. 9: 363-78. PMID 8527612 DOI: 10.1111/J.1365-2036.1995.Tb00394.X  0.353
1995 Vladimirova NM, Potapenko NA, Sachs G, Modyanov NN. Determination of the sidedness of the carboxy-terminus of the Na+/K(+)ATPase alpha-subunit using lactoperoxidase iodination. Biochimica Et Biophysica Acta. 1233: 175-84. PMID 7865541 DOI: 10.1016/0005-2736(94)00247-M  0.368
1995 Hirschowitz BI, Keeling D, Lewin M, Okabe S, Parsons M, Sewing K, Wallmark B, Sachs G. Pharmacological aspects of acid secretion Digestive Diseases and Sciences. 40. PMID 7859583 DOI: 10.1007/Bf02214869  0.451
1995 Kraut JA, Starr F, Sachs G, Reuben M. Expression of gastric and colonic H(+)-K(+)-ATPase in the rat kidney. The American Journal of Physiology. 268: F581-7. PMID 7733314 DOI: 10.1152/ajprenal.1995.268.4.F581  0.326
1995 Sachs G, Shin JM, Briving C, Wallmark B, Hersey S. The pharmacology of the gastric acid pump: The H+,K+ ATPase Annual Review of Pharmacology and Toxicology. 35: 277-305. PMID 7598495 DOI: 10.1146/Annurev.Pa.35.040195.001425  0.469
1995 Bayle D, Weeks D, Sachs G. The membrane topology of the rat sarcoplasmic and endoplasmic reticulum calcium ATPases by in vitro translation scanning. The Journal of Biological Chemistry. 270: 25678-84. PMID 7592746 DOI: 10.1074/Jbc.270.43.25678  0.323
1995 Gedda K, Scott D, Besancon M, Lorentzon P, Sachs G. Turnover of the gastric H+,K(+)-adenosine triphosphatase alpha subunit and its effect on inhibition of rat gastric acid secretion. Gastroenterology. 109: 1134-41. PMID 7557078 DOI: 10.1016/0016-5085(95)90571-5  0.474
1995 Geibel J, Abraham R, Modlin I, Sachs G. Gastrin-stimulated changes in Ca2+ concentration in parietal cells depends on adenosine 3',5'-cyclic monophosphate levels. Gastroenterology. 109: 1060-7. PMID 7557070 DOI: 10.1016/0016-5085(95)90563-4  0.324
1995 Zeng N, Zeng TK, Walsh JH, Sachs G. Identification of isolated gastric endocrine cells using video imaging of intracellular calcium Gastroenterology. 108: A1020. DOI: 10.1016/0016-5085(95)28383-8  0.332
1995 Scott D, Melchers K, Sachs G. The regulation of pH by Helicobacter pylori using the fluorescent pH indicator dye, BCECF Gastroenterology. 108: A215. DOI: 10.1016/0016-5085(95)23520-5  0.312
1995 Melchers K, Weitzenegger T, Steinhilber W, Sachs G, Schäfer KP. A novel P type ATPase cloned from Helicobacter pylori Gastroenterology. 108: A165. DOI: 10.1016/0016-5085(95)23322-9  0.358
1995 Gedda K, Lorentzon P, Sachs G. The turnover and recovery of the gastric H,K ATPase alpha subunit following inhibition of acid secretion Gastroenterology. 108: A99. DOI: 10.1016/0016-5085(95)23061-0  0.45
1994 Edelman JL, Sachs G, Adorante JS. Ion transport asymmetry and functional coupling in bovine pigmented and nonpigmented ciliary epithelial cells. The American Journal of Physiology. 266: C1210-21. PMID 8203485 DOI: 10.1152/Ajpcell.1994.266.5.C1210  0.335
1994 Tari A, Yamamoto G, Yonei Y, Sumii M, Sumii K, Haruma K, Kajiyama G, Wu V, Sachs G, Walsh JH. Effect of histamine on rat gastric H+-K+-ATPase α-subunit expression American Journal of Physiology - Gastrointestinal and Liver Physiology. 266. PMID 8166283 DOI: 10.1152/ajpgi.1994.266.3.G444  0.305
1994 Bamberg K, Nylander S, Helander KG, Lundberg LG, Sachs G, Helander HF. In situ hybridization of mRNA for the gastric H+,K(+)-ATPase in rat oxyntic mucosa. Biochimica Et Biophysica Acta. 1190: 355-9. PMID 8142436 DOI: 10.1016/0005-2736(94)90094-9  0.438
1994 Scott DR, Besancon M, Sachs G, Helander H. Effects of antisecretory agents on parietal cell structure and H/K-ATPase levels in rabbit gastric mucosa in vivo. Digestive Diseases and Sciences. 39: 2118-26. PMID 7924730 DOI: 10.1007/Bf02090359  0.392
1994 Reuben M, Rising L, Prinz C, Hersey S, Sachs G. Cloning and expression of the rabbit gastric CCK-A receptor Bba - Gene Structure and Expression. 1219: 321-327. PMID 7918628 DOI: 10.1016/0167-4781(94)90055-8  0.378
1994 Prinz C, Scott DR, Hurwitz D, Helander HF, Sachs G. Gastrin effects on isolated rat enterochromaffin-like cells in primary culture. The American Journal of Physiology. 267: G663-75. PMID 7524350 DOI: 10.1152/Ajpgi.1994.267.4.G663  0.322
1994 Prinz C, Sachs G, Walsh JH, Coy DH, Wu SV. The somatostatin receptor subtype on rat enterochromaffinlike cells. Gastroenterology. 107: 1067-74. PMID 7523214 DOI: 10.1016/0016-5085(94)90231-3  0.349
1994 Shin JM, Besancon M, Prinz C, Simon A, Sachs G. Continuing development of acid pump inhibitors: site of action of pantoprazole. Alimentary Pharmacology & Therapeutics. 11-23. PMID 7514042 DOI: 10.1111/J.1365-2036.1994.Tb00211.X  0.449
1993 Shin JM, Besancon M, Simon A, Sachs G. The site of action of pantoprazole in the gastric H+/K(+)-ATPase. Biochimica Et Biophysica Acta. 1148: 223-33. PMID 8389196 DOI: 10.1016/0005-2736(93)90133-K  0.432
1993 Sachs G, Shin JM, Besancon M, Prinz C. The continuing development of gastric acid pump inhibitors. Alimentary Pharmacology & Therapeutics. 4-12, discussion 29-. PMID 8387826 DOI: 10.1111/J.1365-2036.1993.Tb00582.X  0.452
1993 Scott DR, Helander HF, Hersey SJ, Sachs G. The site of acid secretion in the mammalian parietal cell Bba - Biomembranes. 1146: 73-80. PMID 8382956 DOI: 10.1016/0005-2736(93)90340-6  0.469
1993 Besancon M, Shin JM, Mercier F, Munson K, Miller M, Hersey S, Sachs G. Membrane topology and omeprazole labeling of the gastric H+,K(+)-adenosinetriphosphatase. Biochemistry. 32: 2345-2355. PMID 8382947 DOI: 10.1021/Bi00060A028  0.36
1993 Prinz C, Kajimura M, Scott DR, Mercier F, Helander HF, Sachs G. Histamine secretion from rat enterochromaffinlike cells. Gastroenterology. 105: 449-61. PMID 7687574 DOI: 10.1016/0016-5085(93)90719-S  0.368
1993 Mercier F, Bayle D, Besancon M, Joys T, Shin JM, Lewin MJM, Prinz C, Reuben MA, Soumarmon A, Wong H, Walsh JH, Sachs G. Antibody epitope mapping of the gastric H+/K(+)-ATPase. Biochimica Et Biophysica Acta. 1149: 151-165. PMID 7686397 DOI: 10.1016/0005-2736(93)90036-Y  0.364
1993 Supplisson S, Loo DD, Sachs G. Whole-cell currents in isolated resting Necturus gastric oxynticopeptic cells. The Journal of Physiology. 463: 57-82. PMID 7504108  0.738
1993 Scott DR, Munson K, Modyanov N, Sachs G. Determination of the sidedness of the C-terminal region of the gastric H,K-ATPase alpha subunit. Biochimica Et Biophysica Acta. 1112: 246-50. PMID 1333805 DOI: 10.1016/0005-2736(92)90398-6  0.356
1992 Sachs G, Munson K. Mammalian phosphorylating ion-motive ATPases. Current Opinion in Cell Biology. 3: 685-94. PMID 1722984 DOI: 10.1016/0955-0674(91)90042-W  0.369
1992 Sun XP, Supplisson S, Torres R, Sachs G, Mayer E. Characterization of large-conductance chloride channels in rabbit colonic smooth muscle. The Journal of Physiology. 448: 355-82. PMID 1375640  0.683
1992 Pope AJ, Sachs G. Reversible inhibitors of the gastric (H+/K+)-ATPase as both potential therapeutic agents and probes of pump function. Biochemical Society Transactions. 20: 566-72. PMID 1330781 DOI: 10.1042/Bst0200566  0.43
1992 Bamberg K, Mercier F, Reuben MA, Kobayashi Y, Munson KB, Sachs G. cDNA cloning and membrane topology of the rabbit gastric H+/K+-ATPase α-subunit Biochimica Et Biophysica Acta. 1131: 69-77. PMID 1316171 DOI: 10.1016/0167-4781(92)90100-E  0.429
1992 Sachs G. The gastric H,K atpase Regulatory Peptides. 40: 241. DOI: 10.1016/0167-0115(92)90400-O  0.348
1991 Pedemonte CH, Sachs G, Kaplan JH. An intrinsic membrane glycoprotein with cytosolically oriented n-linked sugars. Proceedings of the National Academy of Sciences of the United States of America. 87: 9789-93. PMID 2175915 DOI: 10.1073/Pnas.87.24.9789  0.306
1991 Sachs G, Scott D. Cell digestion and genotoxicity assessment in gastric mucosa. Digestion. 31-4. PMID 2093012 DOI: 10.1159/000200512  0.349
1991 Supplisson S, Loo DD, Sachs G. Diversity of K+ channels in the basolateral membrane of resting Necturus oxyntic cells. The Journal of Membrane Biology. 123: 209-21. PMID 1744900 DOI: 10.1007/Bf01870404  0.71
1991 Mayer EA, Sun XP, Supplisson S, Kodner A, Regoli M, Sachs G. Neurokinin receptor-mediated regulation of [Ca]i and Ca-sensitive ion channels in mammalian colonic muscle. Annals of the New York Academy of Sciences. 632: 439-41. PMID 1719899 DOI: 10.1111/J.1749-6632.1991.Tb33149.X  0.689
1991 Tari A, Wu V, Sumii M, Sachs G, Walsh JH. Regulation of rat gastric H+/K+-ATPase α-subunit mRNA by omeprazole Biochimica Et Biophysica Acta. 1129: 49-56. PMID 1684516 DOI: 10.1016/0167-4781(91)90211-4  0.413
1990 Hirschowitz BI, Sachs G. Reversal of insulin inhibition of gastric secretion by intravenous injection of potassium. The American Journal of Digestive Diseases. 11: 217-30. PMID 4952748 DOI: 10.1007/Bf02233903  0.375
1990 Scott D, Reuben M, Zampighi G, Sachs G. Cell isolation and genotoxicity assessment in gastric mucosa. Digestive Diseases and Sciences. 35: 1217-1225. PMID 2209289 DOI: 10.1007/Bf01536410  0.357
1990 Sachs G, Munson K, Hall K, Hersey SJ. Gastric H+, K+-ATPase as a therapeutic target in peptic ulcer disease Digestive Diseases and Sciences. 35: 1537-1544. PMID 2174766 DOI: 10.1007/BF01540572  0.342
1990 Reuben MA, Lasater LS, Sachs G. Characterization of a β subunit of the gastric H+/K+-transporting ATPase Proceedings of the National Academy of Sciences of the United States of America. 87: 6767-6771. PMID 2168558 DOI: 10.1073/Pnas.87.17.6767  0.406
1990 Wallmark B, Lorentzon P, Sachs G. The gastric H+,K(+)-ATPase. Journal of Internal Medicine. Supplement. 732: 3-8. PMID 2166525 DOI: 10.1111/J.1365-2796.1990.Tb01465.X  0.465
1990 Hall K, Perez G, Anderson D, Gutierrez C, Munson K, Hersey SJ, Kaplan JH, Sachs G. Location of the carbohydrates present in the HK-ATPase vesicles isolated from hog gastric mucosa Biochemistry. 29: 701-706. PMID 2159787 DOI: 10.1021/Bi00455A016  0.388
1990 Fryklund J, Gedda K, Scott D, Sachs G, Wallmark B. Coupling of H(+)-K(+)-ATPase activity and glucose oxidation in gastric glands. The American Journal of Physiology. 258: G719-27. PMID 2159239 DOI: 10.1152/Ajpgi.1990.258.5.G719  0.434
1989 Sachs G, Munson K, Balaji VN, Aures-Fischer D, Hersey SJ, Hall K. Functional domains of the gastric HK ATPase Journal of Bioenergetics and Biomembranes. 21: 573-588. PMID 2556379 DOI: 10.1007/Bf00808114  0.438
1989 Hersey SJ, Perez A, Matheravidathu S, Sachs G. Gastric H+-K+-ATPase in situ: evidence for compartmentalization American Journal of Physiology - Gastrointestinal and Liver Physiology. 257. PMID 2552824 DOI: 10.1152/ajpgi.1989.257.4.G539  0.328
1989 Smolka A, Sachs G, Lorentzon P. Cell-free synthesis of rat and rabbit gastric proton pump Gastroenterology. 97: 873-881. PMID 2550309 DOI: 10.1016/0016-5085(89)91491-1  0.401
1989 Helander HF, Anderson D, Helander KG, Smolka A, Sachs G. Immunocytochemical studies of gastric H+,K+-ATPase in the developing rat. Scandinavian Journal of Gastroenterology. 24: 863-9. PMID 2529628 DOI: 10.3109/00365528909089227  0.399
1989 Sachs G, Wallmark B. The Gastric H+,K+-ATPase: The Site of Action of Omeprazole Scandinavian Journal of Gastroenterology. 24: 3-11. DOI: 10.3109/00365528909091236  0.485
1988 Sachs G, Muallem S, Hersey SJ. Passive and active transport in the parietal cell Comparative Biochemistry and Physiology -- Part a: Physiology. 90: 727-731. PMID 2902980 DOI: 10.1016/0300-9629(88)90691-3  0.424
1988 Sachs G, Carlsson E, Lindberg P, Wallmark B. Gastric H,K-ATPase as therapeutic target. Annual Review of Pharmacology and Toxicology. 28: 269-84. PMID 2898235 DOI: 10.1146/Annurev.Pa.28.040188.001413  0.433
1988 Abon EC, Im WB, Sachs G. [50] Preparation of gastric H+, K+-ATPase Methods in Enzymology. 157: 649-654. PMID 2852756 DOI: 10.1016/0076-6879(88)57112-4  0.455
1988 Munson KB, Sachs G. Inactivation of H+,K+-ATPase by a K+-competitive photoaffinity inhibitor. Biochemistry. 27: 3932-8. PMID 2843221 DOI: 10.1021/Bi00411A007  0.406
1988 Hersey SJ, Steiner L, Mendlein J, Rabon E, Sachs G. SCH28080 prevents omeprazole inhibition of the gastric H+/K+-ATPase Biochimica Et Biophysica Acta (Bba)/Protein Structure and Molecular. 956: 49-57. PMID 2841979 DOI: 10.1016/0167-4838(88)90296-8  0.487
1988 Hersey SJ, Steiner L, Matheravidathu S, Sachs G. Gastric H+-K+-ATPase in situ: Relation to secretory state American Journal of Physiology - Gastrointestinal and Liver Physiology. 254. PMID 2837098 DOI: 10.1152/ajpgi.1988.254.6.G856  0.317
1988 Malinowska DH, Sachs G, Cuppoletti J. Gastric H+ secretion: histamine (cAMP-mediated) activation of protein phosphorylation Biochimica Et Biophysica Acta (Bba) - Bioenergetics. 972: 95-109. DOI: 10.1016/S0005-2728(88)80096-3  0.369
1987 Bin IW, Davis JP, Blakeman DP, Sachs G, Robert A. Gastric antisecretory activity of cycloheximide due to inhibition of protein synthesis Biochimica Et Biophysica Acta. 899: 285-294. PMID 3034329 DOI: 10.1016/0005-2736(87)90410-X  0.458
1987 Lorentzon P, Jackson R, Wallmark B, Sachs G. Inhibition of (H+ + K+)-ATPase by omeprazole in isolated gastric vesicles requires proton transport. Biochimica Et Biophysica Acta. 897: 41-51. PMID 3026477 DOI: 10.1016/0005-2736(87)90313-0  0.439
1987 Cuppoletti J, Aures-Fischer D, Sachs G. The lysosomal H+ pump: 8-azido-ATP inhibition and the role of chloride in H+ transport. Biochimica Et Biophysica Acta. 899: 276-84. PMID 2953391 DOI: 10.1016/0005-2736(87)90409-3  0.391
1987 Ueda S, Loo DD, Sachs G. Regulation of K+ channels in the basolateral membrane of Necturus oxyntic cells. The Journal of Membrane Biology. 97: 31-41. PMID 2441066 DOI: 10.1007/Bf01869612  0.345
1987 Sachs G, Tache Y, Debas HT, Jacobson ED, Freston JW. Control of gastric secretion The American Journal of Medicine. 83: 307-328. DOI: 10.1016/0002-9343(87)90703-0  0.375
1986 Sachs G. The parietal cell as a therapeutic target. Scandinavian Journal of Gastroenterology. Supplement. 118: 1-10. PMID 2425413 DOI: 10.3109/00365528609090880  0.417
1985 Im WB, Blakeman DP, Sachs G. Reversal of antisecretory activity of omeprazole by sulfhydryl compounds in isolated rabbit gastric glands. Biochimica Et Biophysica Acta. 845: 54-9. PMID 3978129 DOI: 10.1016/0167-4889(85)90054-0  0.431
1985 Hersey SJ, Sachs G, Kasbekar DK. Acid secretion by frog gastric mucosa is electroneutral The American Journal of Physiology. 248. PMID 3970205 DOI: 10.1152/Ajpgi.1985.248.2.G246  0.438
1985 Berglindh T, Sachs G. Emerging strategies in ulcer therapy: pumps and receptors. Scandinavian Journal of Gastroenterology. Supplement. 108: 7-14. PMID 2988110 DOI: 10.3109/00365528509095815  0.399
1984 Im WB, Blakeman DP, Mendlein J, Sachs G. Inhibition of (H+ + K+)-ATPase and H+ accumulation in hog gastric membranes by trifluoperazine, verapamil and 8-(N,N-diethylamino)octyl-3,4,5-trimethoxybenzoate. Biochimica Et Biophysica Acta. 770: 65-72. PMID 6320882 DOI: 10.1016/0005-2736(84)90074-9  0.468
1983 Smolka A, Helander HF, Sachs G. Monoclonal antibodies against gastric H+ + K+ ATPase. The American Journal of Physiology. 245: G589-96. PMID 6312812 DOI: 10.1152/Ajpgi.1983.245.4.G589  0.348
1983 Jackson RJ, Mendlein J, Sachs G. Interaction of fluorescein isothiocyanate with the (H+ + K+)-ATPase. Biochimica Et Biophysica Acta. 731: 9-15. PMID 6303415 DOI: 10.1016/0005-2736(83)90391-7  0.409
1983 Faller L, Jackson R, Malinowska D, Mukidjam E, Rabon E, Saccomani G, Sachs G, Smolka A. Mechanistic aspects of gastric (H+ + K+)-ATPase. Annals of the New York Academy of Sciences. 402: 146-63. PMID 6301328 DOI: 10.1111/J.1749-6632.1982.Tb25738.X  0.455
1983 Wallmark B, Sachs G, Mardh S, Fellenius E. Inhibition of gastric (H+ + K+)-ATPase by the substituted benzimidazole, picoprazole. Biochimica Et Biophysica Acta. 728: 31-8. PMID 6299338 DOI: 10.1016/0005-2736(83)90433-9  0.46
1983 Malinowska DH, Cuppoletti J, Sachs G. Cl- requirement of acid secretion in isolated gastric glands. The American Journal of Physiology. 245: G573-81. PMID 6194697 DOI: 10.1152/Ajpgi.1983.245.4.G573  0.388
1983 Faller LD, Rabon E, Sachs G. Vanadate binding to the gastric H,K-ATPase and inhibition of the enzyme's catalytic and transport activities. Biochemistry. 22: 4676-85. PMID 6138094 DOI: 10.1021/Bi00289A011  0.404
1982 Burnham C, Munzesheimer C, Rabon E, Sachs G. Ion pathways in renal brush border membranes. Biochimica Et Biophysica Acta. 685: 260-72. PMID 7066312 DOI: 10.1016/0005-2736(82)90066-9  0.397
1982 Graves C, Sachs G. Quantitation of corneal endothelial potentials using a carbocyanine dye. Biochimica Et Biophysica Acta. 685: 27-31. PMID 6977376 DOI: 10.1016/0005-2736(82)90030-X  0.357
1982 Sachs G, Faller LD, Rabon E. Proton/hydroxyl transport in gastric and intestinal epithelia. The Journal of Membrane Biology. 64: 123-35. PMID 6460107 DOI: 10.1007/Bf01870878  0.39
1982 Koelz HR, Hersey SJ, Sachs G, Chew CS. Pepsinogen release from isolated gastric glands. The American Journal of Physiology. 243: G218-25. PMID 6287866 DOI: 10.1152/Ajpgi.1982.243.3.G218  0.369
1982 Rabon E, Sachs G, Mårdh S, Wallmark B. ATP/ADP exchange activity of gastric (H+ +K+)-ATPase. Biochimica Et Biophysica Acta. 688: 515-24. PMID 6285970 DOI: 10.1016/0005-2736(82)90363-7  0.392
1982 Koelz HR, Sachs G, Berglindh T. Cation effects on acid secretion in rabbit gastric glands. The American Journal of Physiology. 241: G431-42. PMID 6272585 DOI: 10.1152/Ajpgi.1981.241.5.G431  0.411
1982 Jackson RJ, Sachs G. Identification of gastric cyclic AMP binding proteins. Biochimica Et Biophysica Acta. 717: 453-8. PMID 6181814 DOI: 10.1016/0304-4165(82)90287-2  0.371
1982 Sachs G, Wallmark B, Saccomam G, Rabon E, Stewart HB, Dibona DR, Berglindh T. Chapter 8 The ATP-Dependent Component of Gastric Acid Secretion Current Topics in Membranes and Transport. 16: 135-159. DOI: 10.1016/S0070-2161(08)60698-X  0.358
1981 Heinz A, Jackson JW, Richey BE, Sachs G, Schafer JA. Amino Acid Transport and stimulation by substrates in the absence of a Na2+ electrochemical potential gradient. The Journal of Membrane Biology. 62: 149-60. PMID 7277474 DOI: 10.1007/Bf01870207  0.362
1981 Malinowska DH, Koelz HR, Hersey SJ, Sachs G. Properties of the gastric proton pump in unstimulated permeable gastric glands Proceedings of the National Academy of Sciences of the United States of America. 78: 5908-5912. PMID 6272324 DOI: 10.1073/Pnas.78.9.5908  0.473
1981 Rabon EC, Sachs G. Thallium interaction with the gastric (K, H)-ATPase. The Journal of Membrane Biology. 62: 19-27. PMID 6268794 DOI: 10.1007/Bf01870196  0.481
1981 Heinz A, Sachs G, Schafer JA. Evidence for activation of an active electrogenic proton pump in Ehrlich ascites tumor cells during glycolysis The Journal of Membrane Biology. 61: 143-153. PMID 6268791 DOI: 10.1007/Bf01870520  0.342
1981 Sachs G, Berglindh T, Rabon E, Wallmark B, Barcellona ML, Stewart HB, Saccomani G. The interaction of K+ with gastric parietal cells and gastric ATPase. Annals of the New York Academy of Sciences. 358: 118-37. PMID 6259985 DOI: 10.1111/J.1749-6632.1980.Tb15391.X  0.479
1981 Fellenius E, Berglindh T, Sachs G, Olbe L, Elander B, Sjöstrand SE, Wallmark B. Substituted benzimidazoles inhibit gastric acid secretion by blocking (H+ + K+)ATPase. Nature. 290: 159-61. PMID 6259537 DOI: 10.1038/290159A0  0.482
1981 Wallmark B, Brändström A, Saccomani G, Sachs G. CATALYTIC CYCLE OF GASTRIC H+ + K+-ATPase Biochemical Society Transactions. 9: 220P-220P. DOI: 10.1042/Bst009220Pa  0.445
1980 Berglindh T, Sachs G, Takeguchi N. Ca2+-dependent secretagogue stimulation in isolated rabbit gastric glands. The American Journal of Physiology. 239: G90-4. PMID 6250412 DOI: 10.1152/Ajpgi.1980.239.2.G90  0.361
1980 Sachs G, Berglindh T, Rabon E, Stewart HB, Barcellona ML, Wallmark B, Saccomani G. Aspects of parietal cell biology: cells and vesicles. Annals of the New York Academy of Sciences. 341: 312-34. PMID 6249150 DOI: 10.1111/J.1749-6632.1980.Tb47181.X  0.435
1980 Rabon E, Takeguchi N, Sachs G. Water and salt permeability of gastric vesicles. The Journal of Membrane Biology. 53: 109-17. PMID 6247494 DOI: 10.1007/Bf01870579  0.314
1980 Chew CS, Hersey SJ, Sachs G, Berglindh T. Histamine responsiveness of isolated gastric glands. The American Journal of Physiology. 238: G312-20. PMID 6246807 DOI: 10.1152/Ajpgi.1980.238.4.G312  0.373
1980 Berglindh T, Dibona DR, Ito S, Sachs G. Probes of parietal cell function. The American Journal of Physiology. 238: G165-76. PMID 6245587 DOI: 10.1152/Ajpgi.1980.238.3.G165  0.407
1980 DiBona DR, Ito S, Berglindh T, Sachs G. Cellular site of gastric acid secretion. Proceedings of the National Academy of Sciences of the United States of America. 76: 6689-93. PMID 42918 DOI: 10.1073/Pnas.76.12.6689  0.424
1979 Mircheff AK, Sachs G, Hanna SD, Labiner CS, Rabon E, Douglas AP, Walling MW, Wright EM. Highly purified basal lateral plasma membranes from rat duodenum. Physical criteria for purity The Journal of Membrane Biology. 50: 343-363. PMID 513118 DOI: 10.1007/Bf01868897  0.471
1979 Saccomani G, Helander HF, Crago S, Chang HH, Dailey DW, Sachs G. Characterization of gastric mucosal membranes. X. Immunological studies of gastric (H+ + K+)-ATPase. The Journal of Cell Biology. 83: 271-83. PMID 159310 DOI: 10.1083/jcb.83.2.271  0.319
1979 Rabon E, Saccomani G, Kasbekar DK, Sachs G. Transport characteristics of frog gastric membranes. Biochimica Et Biophysica Acta. 551: 432-47. PMID 154347 DOI: 10.1016/0005-2736(89)90018-7  0.412
1979 Saccomani G, Chang HH, Spisni A, Helander HF, Spitzer HL, Sachs G. Effect of phospholipase A2 on purified gastric vesicles. Journal of Supramolecular Structure. 11: 429-44. PMID 44534 DOI: 10.1002/Jss.400110402  0.426
1979 Rabon E, Kajdos I, Sachs G. Induction of a chloride conductance in gastric vesicles by limited trypsin or chymotrypsin digestion or ageing. Biochimica Et Biophysica Acta. 556: 469-78. PMID 39602 DOI: 10.1016/0005-2736(79)90134-2  0.412
1978 Koelz HR, Fischer JA, Sachs G, Blum AL. Specific effect of acetylsalicylic acid on cation transport of isolated gastric mucosal cells The American Journal of Physiology. 235. PMID 677306 DOI: 10.1152/Ajpendo.1978.235.1.E16  0.415
1978 Jackson RJ, Stewart HB, Sachs G. Isolation and purification of normal and malignant colonic plasma membranes. Cancer. 40: 2487-96. PMID 144556 DOI: 10.1002/1097-0142(197711)40:5+<2487::Aid-Cncr2820400915>3.0.Co;2-U  0.304
1978 Rabon E, Chang H, Sachs G. Quantitation of hydrogen ion and potential gradients in gastric plasma membrane vesicles. Biochemistry. 17: 3345-53. PMID 28748 DOI: 10.1021/Bi00609A027  0.445
1978 Sachs G. H+ Pathways and pH Changes in Gastric Tissue Gastroenterology. 75: 750-753. DOI: 10.1016/S0016-5085(19)31693-2  0.385
1977 Rabon EC, Sarau HM, Rehm WS, Sachs G. Redox involvement in acid secretion in the amphibian gastric mucosa. The Journal of Membrane Biology. 35: 189-204. PMID 196090 DOI: 10.1007/Bf01869949  0.354
1977 Goodall MC, Sachs G. Reconstitution of a proton pump from gastric mucosa. The Journal of Membrane Biology. 35: 285-301. PMID 142837 DOI: 10.1007/Bf01869954  0.395
1977 Sachs G. H+ transport by a non-electrogenic gastric ATPase as a model for acid secretion. Reviews of Physiology, Biochemistry and Pharmacology. 79: 133-62. PMID 21439 DOI: 10.1007/Bfb0037090  0.434
1977 Schackmann R, Schwartz A, Saccomani G, Sachs G. Cation transport by gastric H+:K+ ATPase. The Journal of Membrane Biology. 32: 361-81. PMID 17007 DOI: 10.1007/Bf01905228  0.406
1977 Lewin M, Saccomani G, Schackmann R, Sachs G. Use of 1-anilino-8-naphthalene-sulfonate as a probe of gastric vesicle transport. The Journal of Membrane Biology. 32: 301-18. PMID 17006 DOI: 10.1007/Bf01905224  0.372
1977 Chang H, Saccomani G, Rabon E, Schackmann R, Sachs G. Proton transport by gastric membrane vesicles. Biochimica Et Biophysica Acta. 464: 313-27. PMID 12816 DOI: 10.1016/0005-2736(77)90006-2  0.455
1977 Bajaj S, Spenney J, Sachs G. Properties of Gastric Antrum Gastroenterology. 72: 72-77. DOI: 10.1016/S0016-5085(77)80306-5  0.33
1977 Sachs G, Chang H, Rabon E, Shackman R, Sarau H, Saccomani G. Metabolic and Membrane Aspects of Gastric H+ Transport Gastroenterology. 73: 931-940. DOI: 10.1016/S0016-5085(19)31739-1  0.445
1976 Sachs G, Rabon E, Saccomani G, Sarau HM. Redox and ATP in acid secretion. Annals of the New York Academy of Sciences. 264: 456-75. PMID 4003 DOI: 10.1111/J.1749-6632.1975.Tb31503.X  0.32
1975 Spenney JG, Shoemaker RL, Sachs G. Microelectrode studies of fundic gastric mucosa: cellular coupling and shunt conductance. The Journal of Membrane Biology. 19: 105-28. PMID 4431038 DOI: 10.1007/Bf01869973  0.342
1975 Saccomani G, Spenney JG, Urry DW, Sachs G. Preparation and characterization of plasma membrane of cardiac tissue. Journal of Molecular and Cellular Cardiology. 6: 505-21. PMID 4140915 DOI: 10.1016/0022-2828(74)90032-7  0.334
1974 Spenney JG, Saccomani G, Spitzer HL, Tomana M, Sachs G. Characterization of gastric mucosal membranes. Composition of gastric cell membranes and polypeptide fractionation using ionic and nonionic detergents. Archives of Biochemistry and Biophysics. 161: 456-71. PMID 4599313 DOI: 10.1016/0003-9861(74)90328-2  0.346
1974 Shoemaker RL, Buckner E, Spenney JG, Sachs G. Action of Burimamide, a histamine antagonist, on acid secretion in vitro. The American Journal of Physiology. 226: 898-902. PMID 4150859 DOI: 10.1152/Ajplegacy.1974.226.4.898  0.308
1974 Wiebelhaus VD, Blum AL, Sachs G. [70] Isolation of oxyntic cells Methods in Enzymology. 32: 707-717. PMID 4141039 DOI: 10.1016/0076-6879(74)32073-3  0.329
1974 Sachs G, Spenney JG, Saccomani G, Goodall MC. Characterization of gastric mucosal membranes. VI. The presence of channel-forming substances Biochimica Et Biophysica Acta. 332: 233-247. DOI: 10.1016/0005-2736(74)90377-0  0.37
1973 Sachs G, Spenney JG, Shoemaker RL, Goodall MC. Conductance pathways in epithelial tissues. Experimental Eye Research. 16: 241-9. PMID 4270189 DOI: 10.1016/0014-4835(73)90090-0  0.339
1973 Spenney JG, Strych A, Price AH, Helander HF, Sachs G. Properties of ATPase of gastric mucosa. V. Preparation of membranes and mitochondria by zonal centrifugation. Biochimica Et Biophysica Acta. 311: 545-64. PMID 4269718 DOI: 10.1016/0005-2736(73)90129-6  0.382
1973 Sung CP, Jenkins BC, Racey Burns L, Hackney V, Spenney JG, Sachs G, Wiebelhaus VD. Adenyl and guanyl cyclase in rabbit gastric mucosa American Journal of Physiology. 225: 1359-1363. PMID 4148546 DOI: 10.1152/Ajplegacy.1973.225.6.1359  0.358
1972 Blum AL, Hirschowitz BI, Helander HF, Sachs G. Electrical properties of isolated cells of Necturus gastric mucosa. Biochimica Et Biophysica Acta. 241: 261-72. PMID 5159786 DOI: 10.1016/0005-2736(71)90027-7  0.322
1972 Kessler CA, Hirschowitz BI, Burhol PG, Sachs G. Methoxyflurane (Penthrane) anesthesia effect on histamine simulated gastric secretion in the chicken. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 139: 1340-3. PMID 5023331 DOI: 10.3181/00379727-139-36358  0.338
1972 Masotti L, Long MM, Sachs G, Urry DW. The effects of ATP on the CD spectrum of membrane fraction from oxyntic cells. Biochimica Et Biophysica Acta. 255: 420-4. PMID 5011006 DOI: 10.1016/0005-2736(72)90044-2  0.351
1972 Sung CP, Wiebelhaus VD, Jenkins BC, Adlercreutz P, Hirschowitz BI, Sachs G. Heterogeneity of 3',5'-phosphodiesterase of gastric mucosa The American Journal of Physiology. 223: 648-650. PMID 4341297 DOI: 10.1152/Ajplegacy.1972.223.3.648  0.388
1972 Simon B, Kinne R, Sachs G. The presence of a HCO 3 - -ATPase in pancreatic tissue. Biochimica Et Biophysica Acta. 282: 293-300. PMID 4262694 DOI: 10.1016/0005-2736(72)90335-5  0.383
1972 Blum AL, Shah G, St Pierre T, Helander HF, Sung CP, Wiebelhaus VD, Sachs G. Properties of soluble ATPase of gastric mucosa. I. Effect of HCO 3 -. Biochimica Et Biophysica Acta. 249: 101-13. PMID 4258791 DOI: 10.1016/0005-2736(71)90087-3  0.384
1972 Wiebelhaus VD, Sung CP, Helander HF, Shah G, Blum AL, Sachs G. Solubilization of anion ATPase from necturus oxyntic cells. Biochimica Et Biophysica Acta. 241: 49-56. PMID 4256592 DOI: 10.1016/0005-2736(71)90302-6  0.379
1972 Sachs G, Shah G, Strych A, Cline G, Hirschowitz B. Properties of ATPase of gastric mucosa III. Distribution of HCO3−-stimulated ATPase in gastric mucosa Biochimica Et Biophysica Acta (Bba) - Biomembranes. 266: 625-638. DOI: 10.1016/0005-2736(72)90359-8  0.407
1971 Nakajima S, Hirschowitz BI, Shoemaker RL, Sachs G. Inhibition of gastric acid secretion in vitro by C-terminal octapeptide of cholecystokinin. The American Journal of Physiology. 221: 1009-13. PMID 5315530 DOI: 10.1152/Ajplegacy.1971.221.4.1009  0.396
1971 Nakajima S, Hirschowitz BI, Sachs G. Studies on adenyl cyclase in Necturus gastric mucosa. Archives of Biochemistry and Biophysics. 143: 123-6. PMID 4327232 DOI: 10.1016/0003-9861(71)90191-3  0.418
1971 Sachs G, Long MM, Tsuji T, Hirschowitz BI. The effect of hydroxylamine on transport ATPase. Biochimica Et Biophysica Acta. 233: 117-21. PMID 4252904 DOI: 10.1016/0005-2736(71)90363-4  0.311
1971 Blum AL, Shah GT, Wiebelhaus VD, Brennan FT, Helander H, Ceballos R, Sachs G. Pronase Method for Isolation of Viable Cells from Necturus Gastric Mucosa Gastroenterology. 61: 189-200. DOI: 10.1016/S0016-5085(19)33595-4  0.323
1970 Nakajima S, Shoemaker RL, Hirschowitz BI, Sachs G. Comparison of actions of aminophylline and pentagastrin on Necturus gastric mucosa. The American Journal of Physiology. 219: 1259-62. PMID 5473106 DOI: 10.1152/Ajplegacy.1970.219.5.1259  0.386
1970 Shoemaker RL, Makhlouf GM, Sachs G. Action of cholinergic drugs on Necturus gastric mucosa. The American Journal of Physiology. 219: 1056-60. PMID 5459468 DOI: 10.1152/Ajplegacy.1970.219.4.1056  0.346
1970 Nakajima S, Shoemaker RL, Hirschowitz BI, Sachs G. Influence of atropine on resistance, potential, and H+ secretion in isolated gastric mucosa. The American Journal of Physiology. 218: 990-4. PMID 5435432 DOI: 10.1152/Ajplegacy.1970.218.4.990  0.389
1970 Sachs G, Clark LC, Makhlouf GM. The use of fluorocarbon emulsion in the Ussing chamber. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 134: 694-5. PMID 5431356 DOI: 10.3181/00379727-134-34862  0.314
1970 Sachs G, Collier RH, Hirschowitz BI. Action of SCN- on rat liver mitochondria. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 133: 456-9. PMID 5414229 DOI: 10.3181/00379727-133-34496  0.326
1970 Sachs G, Finley EZ, Tsuji T, Hirschowitz BI. Effect of irreversible inhibitors on transport ATPase. Archives of Biochemistry and Biophysics. 134: 497-9. PMID 4242919 DOI: 10.1016/0003-9861(69)90310-5  0.363
1969 Sachs G, Collier RH, Pacifico A, Shoemaker RL, Zweig RA, Hirschowitz BI. Action of thiocyanate on gastric mucosa in vitro. Biochimica Et Biophysica Acta. 173: 509-17. PMID 5769642 DOI: 10.1016/0005-2736(69)90015-7  0.428
1969 Hirschowitz B, Sachs G. Pentagastrin in the Gastric Fistula Dog Gastroenterology. 56: 456-467. DOI: 10.1016/S0016-5085(69)80152-6  0.332
1969 Hirschowitz BI, Sachs G. Atropine Inhibition of Insulin-, Histamine-, and Pentagastrin-Stimulated Gastric Electrolyte and Pepsin Secretion in the Dog Gastroenterology. 56: 693-702. DOI: 10.1016/S0016-5085(69)80030-2  0.34
1968 Ramsay AG, Sachs G. Effect of ouabain on Na+ and K+ excretion in the rat. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 126: 294-8. PMID 6066181 DOI: 10.3181/00379727-126-32428  0.361
1968 Sachs G, Collier RH, Shoemaker RL, Hirschowitz BI. The energy source for gastric H+ secretion. Biochimica Et Biophysica Acta. 162: 210-9. PMID 5682852 DOI: 10.1016/0005-2728(68)90103-5  0.377
1968 Hirschowitz BI, Sachs G. Restoration of Homeostasis During Histamine-Stimulated Gastric Secretion by Rapid Intravenous Injection of KCl Gastroenterology. 54: 898-906. DOI: 10.1016/S0016-5085(68)80162-3  0.443
1967 Shoemaker RL, Hirschowitz BI, Sachs G. Hormonal stimulation of Necturus gastric mucosa in vitro. The American Journal of Physiology. 212: 1013-6. PMID 6023860 DOI: 10.1152/Ajplegacy.1967.212.5.1013  0.375
1967 Hirschowitz BI, Sachs G. Insulin effects on gastric secretion and blood electrolytes modified by injected potassium. The American Journal of Digestive Diseases. 12: 7-18. PMID 6017996 DOI: 10.1007/Bf02235222  0.418
1967 Shoemaker RL, Sachs G, Hirschowitz BI. Secretion by guinea pig gastric mucosa in vitro. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 123: 824-7. PMID 5959025 DOI: 10.3181/00379727-123-31614  0.41
1967 Sachs G, Shoemaker RL, Hirschowitz BL. Effects of sodium removal on acid secretion by the frog gastric mucosa. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 123: 47-52. PMID 5924454 DOI: 10.3181/00379727-123-31398  0.316
1967 Sachs G, Shoemaker R, Hirschowitz BI. The action of amytal on frog gastric mucosa Bba - Bioenergetics. 143: 522-531. PMID 4294893 DOI: 10.1016/0005-2728(67)90057-6  0.401
1967 Sachs G, Rose JD, Hirschowitz BI. Acetyl phosphatase in brain microsomes: a partial reaction of Na+ plus K+ ATPase. Archives of Biochemistry and Biophysics. 119: 277-81. PMID 4293189 DOI: 10.1016/0003-9861(67)90456-0  0.348
1966 Hirschowitz BI, Sachs G. Vagal gastric secretory stimulation by 2-deoxy-D-glucose. The American Journal of Physiology. 209: 452-60. PMID 5320025 DOI: 10.1152/Ajplegacy.1965.209.3.452  0.342
1966 Sachs G, Hirschowitz BI. Effect of diisopropyl fluorophosphate on gastric secretion and gastric ATPase. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 120: 702-4. PMID 4221828 DOI: 10.3181/00379727-120-30630  0.444
1965 Sachs G, Mitch WE, Hirschowitz BI. Frog gastric mucosal ATPase. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 119: 1023-7. PMID 4220827 DOI: 10.3181/00379727-119-30366  0.399
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