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Herman N. Eisen - Publications

Affiliations: 
Biology Massachusetts Institute of Technology, Cambridge, MA, United States 
Area:
Cancer Immunology
Website:
http://ki.mit.edu/people/faculty/eisen

137 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Kang M, Eisen TJ, Eisen EA, Chakraborty AK, Eisen HN. Affinity Inequality among Serum Antibodies That Originate in Lymphoid Germinal Centers. Plos One. 10: e0139222. PMID 26444899 DOI: 10.1371/Journal.Pone.0139222  0.354
2015 Li Y, Shen C, Zhu B, Shi F, Eisen HN, Chen J. Persistent Antigen and Prolonged AKT-mTORC1 Activation Underlie Memory CD8 T Cell Impairment in the Absence of CD4 T Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 26163589 DOI: 10.4049/Jimmunol.1500451  0.392
2015 Wang S, Mata-Fink J, Kriegsman B, Hanson M, Irvine DJ, Eisen HN, Burton DR, Wittrup KD, Kardar M, Chakraborty AK. Manipulating the selection forces during affinity maturation to generate cross-reactive HIV antibodies. Cell. 160: 785-97. PMID 25662010 DOI: 10.1016/J.Cell.2015.01.027  0.373
2014 Eisen HN. Affinity enhancement of antibodies: how low-affinity antibodies produced early in immune responses are followed by high-affinity antibodies later and in memory B-cell responses. Cancer Immunology Research. 2: 381-92. PMID 24795350 DOI: 10.1158/2326-6066.Cir-14-0029  0.448
2013 Drake A, Joshi NS, Szeto GL, Zhu E, Eisen HN, Irvine DJ. Koch Institute Symposium on Cancer Immunology and Immunotherapy. Cancer Immunology Research. 1: 217-222. PMID 24466562 DOI: 10.1158/2326-6066.Cir-13-0116  0.305
2013 Eisen HN, Chakraborty AK. Immunopaleontology reveals how affinity enhancement is achieved during affinity maturation of antibodies to influenza virus. Proceedings of the National Academy of Sciences of the United States of America. 110: 7-8. PMID 23284164 DOI: 10.1073/Pnas.1219396110  0.373
2012 Eisen HN, Hou XH, Shen C, Wang K, Tanguturi VK, Smith C, Kozyrytska K, Nambiar L, McKinley CA, Chen J, Cohen RJ. Promiscuous binding of extracellular peptides to cell surface class I MHC protein. Proceedings of the National Academy of Sciences of the United States of America. 109: 4580-5. PMID 22403068 DOI: 10.1073/Pnas.1201586109  0.362
2011 Stone JD, Artyomov MN, Chervin AS, Chakraborty AK, Eisen HN, Kranz DM. Interaction of streptavidin-based peptide-MHC oligomers (tetramers) with cell-surface TCRs. Journal of Immunology (Baltimore, Md. : 1950). 187: 6281-90. PMID 22102724 DOI: 10.4049/Jimmunol.1101734  0.442
2010 Eisen HN, Chakraborty AK. Evolving concepts of specificity in immune reactions. Proceedings of the National Academy of Sciences of the United States of America. 107: 22373-80. PMID 21173256 DOI: 10.1073/Pnas.1012051108  0.387
2010 Shen CH, Talay O, Mahajan VS, Leskov IB, Eisen HN, Chen J. Antigen-bearing dendritic cells regulate the diverse pattern of memory CD8 T-cell development in different tissues. Proceedings of the National Academy of Sciences of the United States of America. 107: 22587-92. PMID 21149737 DOI: 10.1073/Pnas.1016350108  0.439
2010 Mouquet H, Scheid JF, Zoller MJ, Krogsgaard M, Ott RG, Shukair S, Artyomov MN, Pietzsch J, Connors M, Pereyra F, Walker BD, Ho DD, Wilson PC, Seaman MS, Eisen HN, et al. Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation. Nature. 467: 591-5. PMID 20882016 DOI: 10.1038/Nature09385  0.326
2009 Chervin AS, Stone JD, Holler PD, Bai A, Chen J, Eisen HN, Kranz DM. The impact of TCR-binding properties and antigen presentation format on T cell responsiveness. Journal of Immunology (Baltimore, Md. : 1950). 183: 1166-78. PMID 19553539 DOI: 10.4049/Jimmunol.0900054  0.416
2008 Bai A, Higham E, Eisen HN, Wittrup KD, Chen J. Rapid tolerization of virus-activated tumor-specific CD8+ T cells in prostate tumors of TRAMP mice. Proceedings of the National Academy of Sciences of the United States of America. 105: 13003-8. PMID 18723683 DOI: 10.1073/Pnas.0805599105  0.41
2008 Shen CH, Ge Q, Talay O, Eisen HN, García-Sastre A, Chen J. Loss of IL-7R and IL-15R expression is associated with disappearance of memory T cells in respiratory tract following influenza infection. Journal of Immunology (Baltimore, Md. : 1950). 180: 171-8. PMID 18097017 DOI: 10.4049/Jimmunol.180.1.171  0.31
2007 Leng Q, Ge Q, Nguyen T, Eisen HN, Chen J. Stage-dependent reactivity of thymocytes to self-peptide--MHC complexes. Proceedings of the National Academy of Sciences of the United States of America. 104: 5038-43. PMID 17360333 DOI: 10.1073/Pnas.0700674104  0.413
2006 Ge Q, Holler PD, Mahajan VS, Nuygen T, Eisen HN, Chen J. Development of CD4+ T cells expressing a nominally MHC class I-restricted T cell receptor by two different mechanisms. Proceedings of the National Academy of Sciences of the United States of America. 103: 1822-7. PMID 16443680 DOI: 10.1073/Pnas.0510561103  0.438
2005 Palliser D, Guillen E, Ju M, Eisen HN. Multiple intracellular routes in the cross-presentation of a soluble protein by murine dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 174: 1879-87. PMID 15699114 DOI: 10.4049/Jimmunol.174.4.1879  0.405
2004 Little SR, Lynn DM, Ge Q, Anderson DG, Puram SV, Chen J, Eisen HN, Langer R. Poly-beta amino ester-containing microparticles enhance the activity of nonviral genetic vaccines. Proceedings of the National Academy of Sciences of the United States of America. 101: 9534-9. PMID 15210954 DOI: 10.1073/Pnas.0403549101  0.338
2004 Rudolph MG, Shen LQ, Lamontagne SA, Luz JG, Delaney JR, Ge Q, Cho BK, Palliser D, McKinley CA, Chen J, Wilson IA, Eisen HN. A peptide that antagonizes TCR-mediated reactions with both syngeneic and allogeneic agonists: functional and structural aspects. Journal of Immunology (Baltimore, Md. : 1950). 172: 2994-3002. PMID 14978103 DOI: 10.4049/Jimmunol.172.5.2994  0.32
2004 Palliser D, Huang Q, Hacohen N, Lamontagne SP, Guillen E, Young RA, Eisen HN. A role for Toll-like receptor 4 in dendritic cell activation and cytolytic CD8+ T cell differentiation in response to a recombinant heat shock fusion protein. Journal of Immunology (Baltimore, Md. : 1950). 172: 2885-93. PMID 14978090 DOI: 10.4049/Jimmunol.172.5.2885  0.366
2004 Ge Q, Bai A, Jones B, Eisen HN, Chen J. Competition for self-peptide-MHC complexes and cytokines between naive and memory CD8+ T cells expressing the same or different T cell receptors. Proceedings of the National Academy of Sciences of the United States of America. 101: 3041-6. PMID 14976256 DOI: 10.1073/Pnas.0307339101  0.436
2003 Vukmanovi? S, Santori FR, Chen J, Ge Q, Eisen HN. Cooperation or sabotage? Self-peptide-MHC complexes influence T-cell responses to antigens [2] Trends in Immunology. 24: 472-473. PMID 12967668 DOI: 10.1016/S1471-4906(03)00209-6  0.312
2003 Ge Q, Bai A, Shen CH, Eisen HN, Chen J. CD4+ T-cell responses to self-peptide--MHC. Trends in Immunology. 24: 186-9. PMID 12697450 DOI: 10.1016/S1471-4906(03)00060-7  0.427
2003 Chen J, Eisen HN, Kranz DM. A model T-cell receptor system for studying memory T-cell development. Microbes and Infection / Institut Pasteur. 5: 233-40. PMID 12681413 DOI: 10.1016/S1286-4579(03)00016-9  0.476
2003 Chen J, Ge Q, Eisen HN. Response to Vukmanović and Santori: Evidence for mixed heterodimeric MHC II molecules Trends in Immunology. 24: 473. DOI: 10.1016/S1471-4906(03)00208-4  0.419
2002 Chen J, Ge Q, Cho B, Eisen HN. T cell proliferation, differentiation, and restoration in lymphopenic individuals: For contributed volumes Advances in Experimental Medicine and Biology. 512: 135-139. PMID 12405197 DOI: 10.1007/978-1-4615-0757-4_18  0.428
2002 Ge Q, Stone JD, Thompson MT, Cochran JR, Rushe M, Eisen HN, Chen J, Stern LJ. Soluble peptide-MHC monomers cause activation of CD8+ T cells through transfer of the peptide to T cell MHC molecules. Proceedings of the National Academy of Sciences of the United States of America. 99: 13729-34. PMID 12374859 DOI: 10.1073/Pnas.212515299  0.466
2002 Ge Q, Hu H, Eisen HN, Chen J. Naïve to memory T-cell differentiation during homeostasis-driven proliferation. Microbes and Infection / Institut Pasteur. 4: 555-8. PMID 11959511 DOI: 10.1016/S1286-4579(02)01572-1  0.42
2002 Ge Q, Hu H, Eisen HN, Chen J. Different contributions of thymopoiesis and homeostasis-driven proliferation to the reconstitution of naive and memory T cell compartments. Proceedings of the National Academy of Sciences of the United States of America. 99: 2989-94. PMID 11880642 DOI: 10.1073/Pnas.052714099  0.412
2002 Ge Q, Palliser D, Eisen HN, Chen J. Homeostatic T cell proliferation in a T cell-dendritic cell coculture system. Proceedings of the National Academy of Sciences of the United States of America. 99: 2983-8. PMID 11854473 DOI: 10.1073/Pnas.052714199  0.458
2002 Sugawa S, Palliser D, Eisen HN, Chen J. How do cultured CD8(+) murine T cell clones survive repeated ligation of the TCR? International Immunology. 14: 23-30. PMID 11751748 DOI: 10.1093/Intimm/14.1.23  0.434
2001 Eisen HN. Specificity and degeneracy in antigen recognition: yin and yang in the immune system. Annual Review of Immunology. 19: 1-21. PMID 11244028 DOI: 10.1146/Annurev.Immunol.19.1.1  0.493
2001 Kageyama S, Tsomides TJ, Fukusen N, Papayannopoulos IA, Eisen HN, Sykulev Y. Potent cytolytic response by a CD8+ CTL clone to multiple peptides from the same protein in association with an allogeneic class I MHC molecule. Journal of Immunology (Baltimore, Md. : 1950). 166: 3028-34. PMID 11207252 DOI: 10.4049/Jimmunol.166.5.3028  0.368
2001 Ge Q, Rao VP, Cho BK, Eisen HN, Chen J. Dependence of lymphopenia-induced T cell proliferation on the abundance of peptide/ MHC epitopes and strength of their interaction with T cell receptors. Proceedings of the National Academy of Sciences of the United States of America. 98: 1728-33. PMID 11172019 DOI: 10.1073/Pnas.98.4.1728  0.454
2001 Cho BK, Lian KC, Lee P, Brunmark A, McKinley C, Chen J, Kranz DM, Eisen HN. Differences in antigen recognition and cytolytic activity of CD8(+) and CD8(-) T cells that express the same antigen-specific receptor. Proceedings of the National Academy of Sciences of the United States of America. 98: 1723-7. PMID 11172018 DOI: 10.1073/Pnas.98.4.1723  0.432
2000 Foote J, Eisen HN. Breaking the affinity ceiling for antibodies and T cell receptors. Proceedings of the National Academy of Sciences of the United States of America. 97: 10679-81. PMID 11005851 DOI: 10.1073/Pnas.97.20.10679  0.479
2000 Cho BK, Rao VP, Ge Q, Eisen HN, Chen J. Homeostasis-stimulated proliferation drives naive T cells to differentiate directly into memory T cells. The Journal of Experimental Medicine. 192: 549-56. PMID 10952724 DOI: 10.1084/Jem.192.4.549  0.442
2000 Cho BK, Palliser D, Guillen E, Wisniewski J, Young RA, Chen J, Eisen HN. A proposed mechanism for the induction of cytotoxic T lymphocyte production by heat shock fusion proteins. Immunity. 12: 263-72. PMID 10755613 DOI: 10.1016/S1074-7613(00)80179-X  0.424
2000 Huang Q, Richmond JF, Suzue K, Eisen HN, Young RA. In vivo cytotoxic T lymphocyte elicitation by mycobacterial heat shock protein 70 fusion proteins maps to a discrete domain and is CD4(+) T cell independent. The Journal of Experimental Medicine. 191: 403-8. PMID 10637285 DOI: 10.1084/Jem.191.2.403  0.385
1999 Cho BK, Wang C, Sugawa S, Eisen HN, Chen J. Functional differences between memory and naive CD8 T cells. Proceedings of the National Academy of Sciences of the United States of America. 96: 2976-81. PMID 10077622 DOI: 10.1073/Pnas.96.6.2976  0.442
1998 Sykulev Y, Vugmeyster Y, Brunmark A, Ploegh HL, Eisen HN. Peptide antagonism and T cell receptor interactions with peptide-MHC complexes. Immunity. 9: 475-83. PMID 9806634 DOI: 10.1016/S1074-7613(00)80631-7  0.433
1998 Vugmeyster Y, Glas R, Pérarnau B, Lemonnier FA, Eisen H, Ploegh H. Major histocompatibility complex (MHC) class I KbDb -/- deficient mice possess functional CD8+ T cells and natural killer cells. Proceedings of the National Academy of Sciences of the United States of America. 95: 12492-7. PMID 9770513 DOI: 10.1073/Pnas.95.21.12492  0.439
1998 Walter JB, Garboczi DN, Fan QR, Zhou X, Walker BD, Eisen HN. A mutant human beta2-microglobulin can be used to generate diverse multimeric class I peptide complexes as specific probes for T cell receptors. Journal of Immunological Methods. 214: 41-50. PMID 9692857 DOI: 10.1016/S0022-1759(98)00035-0  0.413
1998 Delaney JR, Sykulev Y, Eisen HN, Tonegawa S. Differences in the level of expression of class I major histocompatibility complex proteins on thymic epithelial and dendritic cells influence the decision of immature thymocytes between positive and negative selection. Proceedings of the National Academy of Sciences of the United States of America. 95: 5235-40. PMID 9560259 DOI: 10.1073/Pnas.95.9.5235  0.44
1997 Suzue K, Zhou X, Eisen HN, Young RA. Heat shock fusion proteins as vehicles for antigen delivery into the major histocompatibility complex class I presentation pathway. Proceedings of the National Academy of Sciences of the United States of America. 94: 13146-51. PMID 9371814 DOI: 10.1073/Pnas.94.24.13146  0.435
1997 Walter JB, Brander C, Mammen M, Garboczi DN, Kalams SA, Whitesides GM, Walker BD, Eisen HN. Stimulation of human cytotoxic T cells with HIV-1-derived peptides presented by recombinant HLA-A2 peptide complexes. International Immunology. 9: 451-9. PMID 9088983 DOI: 10.1093/Intimm/9.3.451  0.38
1997 Tsomides TJ, Reilly EB, Eisen HN. Anti-melanoma cytotoxic T lymphocytes (CTL) recognize numerous antigenic peptides having 'self' sequences: autoimmune nature of the anti-melanoma CTL response. International Immunology. 9: 327-38. PMID 9040014 DOI: 10.1093/Intimm/9.2.327  0.405
1996 Eisen HN, Sykulev Y, Tsomides TJ. Antigen-specific T-cell receptors and their reactions with complexes formed by peptides with major histocompatibility complex proteins. Advances in Protein Chemistry. 49: 1-56. PMID 8908296 DOI: 10.1016/S0065-3233(08)60487-8  0.476
1996 Sykulev Y, Joo M, Vturina I, Tsomides TJ, Eisen HN. Evidence that a single peptide-MHC complex on a target cell can elicit a cytolytic T cell response. Immunity. 4: 565-71. PMID 8673703 DOI: 10.1016/S1074-7613(00)80483-5  0.426
1995 Sykulev Y, Cohen RJ, Eisen HN. The law of mass action governs antigen-stimulated cytolytic activity of CD8+ cytotoxic T lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 92: 11990-2. PMID 8618829 DOI: 10.1073/Pnas.92.26.11990  0.466
1995 Kageyama S, Tsomides TJ, Sykulev Y, Eisen HN. Variations in the number of peptide-MHC class I complexes required to activate cytotoxic T cell responses. Journal of Immunology (Baltimore, Md. : 1950). 154: 567-76. PMID 7814868  0.32
1994 Tsomides TJ, Eisen HN. T-cell antigens in cancer. Proceedings of the National Academy of Sciences of the United States of America. 91: 3487-9. PMID 8170934 DOI: 10.1073/Pnas.91.9.3487  0.502
1994 Dutz JP, Tsomides TJ, Kageyama S, Rasmussen MH, Eisen HN. A cytotoxic T lymphocyte clone can recognize the same naturally occurring self peptide in association with a self and nonself class I MHC protein. Molecular Immunology. 31: 967-75. PMID 8084337 DOI: 10.1016/0161-5890(94)90091-4  0.458
1994 Sykulev Y, Brunmark A, Tsomides TJ, Kageyama S, Jackson M, Peterson PA, Eisen HN. High-affinity reactions between antigen-specific T-cell receptors and peptides associated with allogeneic and syngeneic major histocompatibility complex class I proteins. Proceedings of the National Academy of Sciences of the United States of America. 91: 11487-91. PMID 7972089 DOI: 10.1073/Pnas.91.24.11487  0.454
1994 Sykulev Y, Brunmark A, Jackson M, Cohen RJ, Peterson PA, Eisen HN. Kinetics and affinity of reactions between an antigen-specific T cell receptor and peptide-MHC complexes. Immunity. 1: 15-22. PMID 7889394 DOI: 10.1016/1074-7613(94)90005-1  0.464
1994 Tsomides TJ, Aldovini A, Johnson RP, Walker BD, Young RA, Eisen HN. Naturally processed viral peptides recognized by cytotoxic T lymphocytes on cells chronically infected by human immunodeficiency virus type 1. The Journal of Experimental Medicine. 180: 1283-93. PMID 7523570 DOI: 10.1084/Jem.180.4.1283  0.359
1993 Su MW, Walden PR, Golan DB, Eisen HN. Cognate peptide-induced destruction of CD8+ cytotoxic T lymphocytes is due to fratricide. Journal of Immunology (Baltimore, Md. : 1950). 151: 658-67. PMID 8335901  0.303
1993 Udaka K, Tsomides TJ, Walden P, Fukusen N, Eisen HN. A ubiquitous protein is the source of naturally occurring peptides that are recognized by a CD8+ T-cell clone. Proceedings of the National Academy of Sciences of the United States of America. 90: 11272-6. PMID 8248240 DOI: 10.1073/Pnas.90.23.11272  0.436
1992 Udaka K, Tsomides TJ, Eisen HN. A naturally occurring peptide recognized by alloreactive CD8+ cytotoxic T lymphocytes in association with a class I MHC protein. Cell. 69: 989-98. PMID 1606619 DOI: 10.1016/0092-8674(92)90617-L  0.488
1992 Sykulev YK, Sherman DA, Cohen RJ, Eisen HN. Quantitation of reversible binding by particle counting: hapten-antibody interaction as a model system. Proceedings of the National Academy of Sciences of the United States of America. 89: 4703-7. PMID 1584807 DOI: 10.1073/Pnas.89.10.4703  0.325
1992 Dutz JP, Walden PR, Eisen HN. Effects of cognate peptides on cytolytic and proliferative activities of cloned cytotoxic T lymphocytes. International Immunology. 4: 571-80. PMID 1378297 DOI: 10.1093/Intimm/4.5.571  0.456
1991 Tsomides TJ, Eisen HN. Antigenic structures recognized by cytotoxic T lymphocytes. The Journal of Biological Chemistry. 266: 3357-60. PMID 1825310  0.304
1991 Tsomides TJ, Walker BD, Eisen HN. An optimal viral peptide recognized by CD8+ T cells binds very tightly to the restricting class I major histocompatibility complex protein on intact cells but not to the purified class I protein. Proceedings of the National Academy of Sciences of the United States of America. 88: 11276-80. PMID 1722325 DOI: 10.1073/Pnas.88.24.11276  0.443
1990 Elliott TJ, Eisen HN. Cytotoxic T lymphocytes recognize a reconstituted class I histocompatibility antigen (HLA-A2) as an allogeneic target molecule. Proceedings of the National Academy of Sciences of the United States of America. 87: 5213-7. PMID 2367533 DOI: 10.1073/Pnas.87.13.5213  0.412
1990 Nagler-Anderson C, Eisen HN. Resistance of normal, unstimulated, CD8+ T cells to lysis by cytotoxic granules from cloned T cell lines. International Immunology. 2: 99-103. PMID 2150923 DOI: 10.1093/Intimm/2.1.99  0.415
1990 Walden PR, Eisen HN. Cognate peptides induce self-destruction of CD8+ cytolytic T lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 87: 9015-9. PMID 2123347 DOI: 10.1073/Pnas.87.22.9015  0.423
1989 Nagler-Anderson C, Lichtenheld M, Eisen HN, Podack ER. Perforin mRNA in primary peritoneal exudate cytotoxic T lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 143: 3440-3. PMID 2584700  0.329
1988 Allbritton NL, Nagler-Anderson C, Elliott TJ, Verret CR, Eisen HN. Target cell lysis by cytotoxic T lymphocytes that lack detectable hemolytic perforin activity. Journal of Immunology (Baltimore, Md. : 1950). 141: 3243-8. PMID 3263417  0.543
1988 Liu MA, Nussbaum SR, Eisen HN. Hormone conjugated with antibody to CD3 mediates cytotoxic T cell lysis of human melanoma cells. Science (New York, N.Y.). 239: 395-8. PMID 3257303  0.39
1988 Nagler-Anderson C, Allbritton NL, Verret CR, Eisen HN. A comparison of the cytolytic properties of murine primary CD8+ cytotoxic T lymphocytes and cloned cytotoxic T cell lines. Immunological Reviews. 103: 111-25. PMID 3134291 DOI: 10.1111/J.1600-065X.1988.Tb00753.X  0.57
1988 Ferguson WS, Verret CR, Reilly EB, Iannini MJ, Eisen HN. Serine esterase and hemolytic activity in human cloned cytotoxic T lymphocytes. The Journal of Experimental Medicine. 167: 528-40. PMID 3126252 DOI: 10.1084/Jem.167.2.528  0.439
1988 Nagler-Anderson C, Verret CR, Firmenich AA, Berne M, Eisen HN. Resistance of primary CD8+ cytotoxic T lymphocytes to lysis by cytotoxic granules from cloned T cell lines. Journal of Immunology (Baltimore, Md. : 1950). 141: 3299-305. PMID 2972770  0.3
1988 Elliott TJ, Eisen HN. Allorecognition of purified major histocompatibility complex glycoproteins by cytotoxic T lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 85: 2728-32. PMID 2451830 DOI: 10.1073/Pnas.85.8.2728  0.415
1988 Allbritton NL, Verret CR, Wolley RC, Eisen HN. Calcium ion concentrations and DNA fragmentation in target cell destruction by murine cloned cytotoxic T lymphocytes. The Journal of Experimental Medicine. 167: 514-27. PMID 2450162 DOI: 10.1084/Jem.167.2.514  0.535
1987 Eisen HN, Verret CR, Firmenich AA, Kranz DM. Resistance of cytolytic T lymphocytes to the lytic components they release. Annales De L'Institut Pasteur. Immunology. 138: 328-31. PMID 3496910 DOI: 10.1016/S0769-2625(87)80089-2  0.304
1987 Cone RD, Reilly EB, Eisen HN, Mulligan RC. Tissue-specific expression of functionally rearranged lambda 1 Ig gene through a retrovirus vector. Science (New York, N.Y.). 236: 954-7. PMID 3107128 DOI: 10.1126/Science.3107128  0.31
1987 Kranz DM, Eisen HN. Resistance of cytotoxic T lymphocytes to lysis by a clone of cytotoxic T lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 84: 3375-9. PMID 2953028 DOI: 10.1073/Pnas.84.10.3375  0.448
1987 Verret CR, Firmenich AA, Kranz DM, Eisen HN. Resistance of cytotoxic T lymphocytes to the lytic effects of their toxic granules. The Journal of Experimental Medicine. 166: 1536-47. PMID 2445890 DOI: 10.1084/Jem.166.5.1536  0.425
1987 Kranz DM, Pasternack MS, Eisen HN. Recognition and lysis of target cells by cytotoxic T lymphocytes. Federation Proceedings. 46: 309-12. PMID 2433165  0.395
1986 Eisen HN. Why affinity progression of antibodies during immune responses is probably not accompanied by parallel changes in the immunoglobulin-like antigen-specific receptors on T cells. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 4: 269-72. PMID 3491609 DOI: 10.1002/Bies.950040609  0.398
1986 Pasternack MS, Verret CR, Liu MA, Eisen HN. Serine esterase in cytolytic T lymphocytes. Nature. 322: 740-3. PMID 3489187 DOI: 10.1038/322740A0  0.441
1986 Reilly EB, Kranz DM, Tonegawa S, Eisen HN. A functional gamma gene formed from known gamma-gene segments is not necessary for antigen-specific responses of murine cytotoxic T lymphocytes. Nature. 321: 878-80. PMID 3487735 DOI: 10.1038/321878A0  0.438
1986 Novotný J, Tonegawa S, Saito H, Kranz DM, Eisen HN. Secondary, tertiary, and quaternary structure of T-cell-specific immunoglobulin-like polypeptide chains. Proceedings of the National Academy of Sciences of the United States of America. 83: 742-6. PMID 3484824 DOI: 10.1073/Pnas.83.3.742  0.356
1986 Hubbard SC, Kranz DM, Longmore GD, Sitkovsky MV, Eisen HN. Glycosylation of the T-cell antigen-specific receptor and its potential role in lectin-mediated cytotoxicity. Proceedings of the National Academy of Sciences of the United States of America. 83: 1852-6. PMID 3081904 DOI: 10.1073/Pnas.83.6.1852  0.379
1985 Kronenberg M, Malissen B, Eisen HN. Genes, structures and function of T lymphocyte antigen receptors. Immunology Today. 6: 281-6. PMID 25290769 DOI: 10.1016/0167-5699(85)90168-9  0.398
1985 Liu MA, Kranz DM, Kurnick JT, Boyle LA, Levy R, Eisen HN. Heteroantibody duplexes target cells for lysis by cytotoxic T lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 82: 8648-52. PMID 3936039 DOI: 10.1073/Pnas.82.24.8648  0.49
1985 Eisen HN, Reilly EB. Lambda chains and genes in inbred mice. Annual Review of Immunology. 3: 337-65. PMID 3933530 DOI: 10.1146/Annurev.Iy.03.040185.002005  0.321
1985 Kranz DM, Saito H, Disteche CM, Swisshelm K, Pravtcheva D, Ruddle FH, Eisen HN, Tonegawa S. Chromosomal locations of the murine T-cell receptor alpha-chain gene and the T-cell gamma gene. Science (New York, N.Y.). 227: 941-5. PMID 3918347 DOI: 10.1126/Science.3918347  0.368
1985 Hayday AC, Saito H, Gillies SD, Kranz DM, Tanigawa G, Eisen HN, Tonegawa S. Structure, organization, and somatic rearrangement of T cell gamma genes. Cell. 40: 259-69. PMID 3917858 DOI: 10.1016/0092-8674(85)90140-0  0.351
1985 Eisen HN, Liu MA, Kranz DM. The central role of the antigen-specific receptor complex in triggering cytolytic activity of cytotoxic T lymphocytes. Bioscience Reports. 5: 885-92. PMID 3879457 DOI: 10.1007/Bf01119900  0.412
1985 Sitkovsky MV, Schwartz MA, Eisen HN. Cell-cell contact proteins in antigen-specific and antigen-nonspecific cellular cytotoxicity. Advances in Experimental Medicine and Biology. 184: 429-49. PMID 3875975 DOI: 10.1007/978-1-4684-8326-0_29  0.477
1985 Pasternack MS, Eisen HN. A novel serine esterase expressed by cytotoxic T lymphocytes. Nature. 314: 743-5. PMID 3873011 DOI: 10.1038/314743A0  0.46
1985 Kranz DM, Saito H, Heller M, Takagaki Y, Haas W, Eisen HN, Tonegawa S. Limited diversity of the rearranged T-cell gamma gene. Nature. 313: 752-5. PMID 3871915 DOI: 10.1038/313752A0  0.399
1985 Heilig JS, Glimcher LH, Kranz DM, Clayton LK, Greenstein JL, Saito H, Maxam AM, Burakoff SJ, Eisen HN, Tonegawa S. Expression of the T-cell-specific gamma gene is unnecessary in T cells recognizing class II MHC determinants. Nature. 317: 68-70. PMID 2412133 DOI: 10.1038/317068A0  0.409
1984 Kranz DM, Sherman DH, Sitkovsky MV, Pasternack MS, Eisen HN. Immunoprecipitation of cell surface structures of cloned cytotoxic T lymphocytes by clone-specific antisera. Proceedings of the National Academy of Sciences of the United States of America. 81: 573-7. PMID 6607474 DOI: 10.1073/Pnas.81.2.573  0.613
1984 Azuma T, Igras V, Reilly EB, Eisen HN. Diversity at the variable-joining region boundary of lambda light chains has a pronounced effect on immunoglobulin ligand-binding activity. Proceedings of the National Academy of Sciences of the United States of America. 81: 6139-43. PMID 6435124 DOI: 10.1073/Pnas.81.19.6139  0.302
1984 Liu T, Reilly EB, Zhang CB, Eisen HN. Frequency of lambda light chain subtypes in mouse antibodies to the 2,4-dinitrophenyl (DNP) group. European Journal of Immunology. 14: 667-72. PMID 6430711 DOI: 10.1002/Eji.1830140715  0.356
1984 Sitkovsky MV, Pasternack MS, Lugo JP, Klein JR, Eisen HN. Isolation and partial characterization of concanavalin A receptors on cloned cytotoxic T lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 81: 1519-23. PMID 6424117 DOI: 10.1073/Pnas.81.5.1519  0.454
1984 Kranz DM, Tonegawa S, Eisen HN. Attachment of an anti-receptor antibody to non-target cells renders them susceptible to lysis by a clone of cytotoxic T lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 81: 7922-6. PMID 6334855 DOI: 10.1073/Pnas.81.24.7922  0.487
1984 Sherman DH, Kranz DM, Eisen HN. Expression of structurally diverse Qa-2-encoded molecules on the surface of cloned cytotoxic T lymphocytes. The Journal of Experimental Medicine. 160: 1421-30. PMID 6333483 DOI: 10.1084/Jem.160.5.1421  0.488
1984 Saito H, Kranz DM, Takagaki Y, Hayday AC, Eisen HN, Tonegawa S. Complete primary structure of a heterodimeric T-cell receptor deduced from cDNA sequences. Nature. 309: 757-62. PMID 6330561 DOI: 10.1038/309757A0  0.419
1984 Saito H, Kranz DM, Takagaki Y, Hayday AC, Eisen HN, Tonegawa S. A third rearranged and expressed gene in a clone of cytotoxic T lymphocytes. Nature. 312: 36-40. PMID 6208487 DOI: 10.1038/312036A0  0.373
1983 Pasternack MS, Sitkovsky MV, Eisen HN. The site of action of N-α-tosyl-L-lysyl-chloromethyl-ketone (TLCK) on cloned cytotoxic T lymphocytes Journal of Immunology. 131: 2477-2483. PMID 6415172  0.33
1983 Onodera Y, Reilly EB, Eisen HN. Synthesis of λ light chain subtypes by stimulated and unstimulated mouse B cells European Journal of Immunology. 13: 739-746. PMID 6413226 DOI: 10.1002/Eji.1830130909  0.363
1982 Sitkovsky MV, Pasternack MS, Eisen HN. Inhibition of cytotoxic T lymphocyte activity by concanavalin A Journal of Immunology. 129: 1372-1376. PMID 6980931  0.322
1982 Burkly LC, Zaugg R, Eisen HN, Wortis HH. Influence of the nude and X-linked immune deficiency genes on expression of κappa and λ light chains European Journal of Immunology. 12: 1033-1039. PMID 6819148 DOI: 10.1002/Eji.1830121209  0.45
1982 Reilly EB, Frackelton AR, Eisen HN. Synthesis of λ1, λ2, and λ3 light chains by mouse spleen B cells European Journal of Immunology. 12: 552-557. PMID 6811287 DOI: 10.1002/Eji.1830120705  0.422
1982 Sakato N, Semma M, Eisen HN, Azuma T. A small hypervariable segment in the variable domain of an immunoglobulin light chain stimulates formation of anti-idiotypic suppressor T cells Proceedings of the National Academy of Sciences of the United States of America. 79: 5396-5400. PMID 6215651 DOI: 10.1073/Pnas.79.17.5396  0.339
1981 Hale AH, Russell JH, d'Angeac AD, Panetti M, Hazelton B, Eisen HN. Periodic fluctuations in resistance of a myeloma tumor (MOPC-315-EL) to cytotoxic T lymphocytes. III. Changes in susceptibility of the tumor cells as they grow in nude mice and in culture Cellular Immunology. 62: 119-131. PMID 6973405 DOI: 10.1016/0008-8749(81)90305-1  0.41
1981 Ross AH, Baltimore D, Eisen HN. Phosphotyrosine-containing proteins isolated by affinity chromatography with antibodies to a synthetic hapten Nature. 294: 654-656. PMID 6171737 DOI: 10.1038/294654A0  0.312
1981 Azuma T, Steiner LA, Eisen HN. Identification of a third type of λ light chain in mouse immunoglobulins Proceedings of the National Academy of Sciences of the United States of America. 78: 569-573. PMID 6165998 DOI: 10.1073/Pnas.78.1.569  0.315
1979 Chang TW, Celis E, Eisen HN, Solomon F. Crawling movements of lymphocytes on and beneath fibroblasts in culture Proceedings of the National Academy of Sciences of the United States of America. 76: 2917-2921. PMID 313569 DOI: 10.1073/Pnas.76.6.2917  0.445
1979 Chang TW, Eisen HN. Lymphomas with cytotoxic activity Nature. 280: 406-408. PMID 313526 DOI: 10.1038/280406A0  0.46
1979 Inbar D, Hale AH, Igras V, Eisen HN. Soluble trinitrophenylated proteins and trinitrophenylated cells as specific inhibitors of target cell lysis by cytotoxic T lymphocytes Cellular Immunology. 42: 298-307. PMID 311693 DOI: 10.1016/0008-8749(79)90195-3  0.41
1979 Loh D, Ross AH, Hale AH, Baltimore D, Eisen HN. Synthetic phospholipid vesicles containing a purified viral antigen and cell membrane proteins stimulate the development of cytotoxic T lymphocytes Journal of Experimental Medicine. 150: 1067-1074. PMID 227980 DOI: 10.1084/Jem.150.5.1067  0.392
1978 Russel JH, Hale AH, Inbar D, Eisen HN. Loss of reactivity of a BALB/c myeloma tumor with allogeneic and syngeneic cytotoxic T lymphocytes European Journal of Immunology. 8: 640-645. PMID 309400 DOI: 10.1002/Eji.1830080907  0.386
1978 Hale AH, Witte ON, Baltimore D, Eisen HN. Vesicular stomatitis virus glycoprotein is necessary for H 2 restricted lysis of infected cells by cytotoxic T lymphocytes Proceedings of the National Academy of Sciences of the United States of America. 75: 970-974. PMID 204941 DOI: 10.1073/Pnas.75.2.970  0.358
1978 Russell JH, Hale AH, Ginns LC, Eisen HN. Periodic loss of reactivity of a myeloma tumor with cytotoxic thymus-derived lymphocytes Proceedings of the National Academy of Sciences of the United States of America. 75: 441-445. PMID 75547 DOI: 10.1073/Pnas.75.1.441  0.303
1977 Sakato N, Hall SH, Eisen HN. Restricted heterogeneity of antibodies to idiotypes of isologous immunoglobulins Immunochemistry. 14: 621-625. PMID 598868 DOI: 10.1016/0019-2791(77)90159-8  0.362
1977 Sakato N, Janeway CA, Eisen HN. Immune responses of BALB/c mice to the idiotype of T15 and of other myeloma proteins of BALB/c origin: implications for an immune network and antibody multispecificity Cold Spring Harbor Symposia On Quantitative Biology. 41: 719-724. PMID 70307 DOI: 10.1101/SQB.1977.041.01.082  0.327
1977 Cohen RJ, Eisen HN. Interactions of macromolecules on cell membranes and restrictions of T-cell specificity by products of the major histocompatibility complex Cellular Immunology. 32: 1-9. DOI: 10.1016/0008-8749(77)90177-0  0.368
1975 Janeway CA, Sakato N, Eisen HN. Recognition of immunoglobulin idiotypes by thymus derived lymphocytes (helper T cells/myeloma proteins/lymphocyte receptors/anti Dnp antibodies) Proceedings of the National Academy of Sciences of the United States of America. 72: 2357-2360. PMID 49059 DOI: 10.1073/pnas.72.6.2357  0.403
1974 Johnston MFM, Eisen HN. Preparation and characterization of antibodies to menadione Biochemistry. 13: 5547-5552. PMID 4477021 DOI: 10.1021/Bi00724A015  0.314
1972 Haimovich J, Eisen HN, Hurwitz E, Givol D. Localization of affinity-labeled residues on the heavy and light chain of two myeloma proteins with anti-hapten activity Biochemistry. 11: 2389-2398. PMID 5064800 DOI: 10.1021/Bi00763A001  0.3
1972 Hannestad K, Kao MS, Eisen HN. Cell-bound myeloma proteins on the surface of myeloma cells: potential targets for the immune system Proceedings of the National Academy of Sciences of the United States of America. 69: 2295-2299. PMID 4626403 DOI: 10.1073/Pnas.69.8.2295  0.396
1972 Lynch RG, Graff RJ, Sirisinha S, Simms ES, Eisen HN. Myeloma proteins as tumor-specific transplantation antigens. Proceedings of the National Academy of Sciences of the United States of America. 69: 1540-4. PMID 4113870 DOI: 10.1073/Pnas.69.6.1540  0.363
1971 Sirisinha S, Eisen HN. Autoimmune-like antibodies to the ligand-binding sites of myeloma proteins Proceedings of the National Academy of Sciences of the United States of America. 68: 3130-3135. PMID 4108872 DOI: 10.1073/Pnas.68.12.3130  0.341
1969 Little JR, Eisen HN. Specificity of the immune response to the 2,4-dinitrophenyl and 2,4,6-trinitrophenyl groups. Ligand binding and fluorescence properties of cross-reacting antibodies Journal of Experimental Medicine. 129: 247-265. PMID 4178351 DOI: 10.1084/Jem.129.2.247  0.376
1968 McGuigan JE, Eisen HN. Differences in spectral properties and tryptophan content among rabbit anti-2,4-dinitrophenyl antibodies of the γG-immunoglobulin class Biochemistry. 7: 1919-1928. PMID 4870336 DOI: 10.1021/Bi00845A041  0.316
1968 Eisen HN, Simms ES, Potter M. Mouse myeloma proteins with antihapten antibody acitivity. The protein produced by plasma cell tumor MOPC-315. Biochemistry. 7: 4126-34. PMID 4177521 DOI: 10.1021/Bi00851A048  0.338
1967 Steiner LA, Eisen HN. An assay for determining the relative affinity of trace amounts of labeled antibodies Journal of Experimental Medicine. 126: 1143-1160. PMID 6069929 DOI: 10.1084/Jem.126.6.1143  0.343
1967 Eisen HN, Little JR, Osterland CK, Simms ES. A Myeloma Protein with Antibody Activity Cold Spring Harbor Symposia On Quantitative Biology. 32: 75-81. DOI: 10.1101/Sqb.1967.032.01.012  0.328
1962 PARKER CW, KERN M, EISEN HN. Polyfunctional dinitrophenyl haptens as reagents for elicitation of immediate type allergic skin responses The Journal of Experimental Medicine. 115: 789-801. PMID 14483915 DOI: 10.1084/JEM.115.4.789  0.475
1960 Velick SF, Parker CW, Eisen HN. EXCITATION ENERGY TRANSFER AND THE QUANTITATIVE STUDY OF THE ANTIBODY HAPTEN REACTION. Proceedings of the National Academy of Sciences of the United States of America. 46: 1470-82. PMID 16590773 DOI: 10.1073/Pnas.46.11.1470  0.542
1959 Kern M, Helmreich E, Eisen HN. A Demonstration Of Antibody Activity On Microsomes. Proceedings of the National Academy of Sciences of the United States of America. 45: 862-867. PMID 16590460 DOI: 10.1073/Pnas.45.6.862  0.318
1959 Kern M, Eisen HN. The Effect Of Antigenic Stimulation On Incorporation Of Phosphate And Methionine Into Proteins Of Isolated Lymph Node Cells Journal of Experimental Medicine. 110: 207-219. PMID 13673135 DOI: 10.1084/Jem.110.2.207  0.315
1955 Carsten ME, Eisen HN. The Specific Interaction of Some Dinitrobenzenes with Rabbit Antibody to Dinitrophenyl-Bovine γ-Globulin1 Journal of the American Chemical Society. 77: 1273-1277. DOI: 10.1021/Ja01610A053  0.322
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