Leon Tremblay - Publications

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70 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Prange S, Metereau E, Maillet A, Lhommée E, Klinger H, Pelissier P, Ibarrola D, Heckemann RA, Castrioto A, Tremblay L, Sgambato V, Broussolle E, Krack P, Thobois S. Early limbic microstructural alterations in apathy and depression in de novo Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 31309609 DOI: 10.1002/mds.27793  0.48
2018 Beaudoin-Gobert M, Météreau E, Duperrier S, Thobois S, Tremblay L, Sgambato V. Pathophysiology of levodopa-induced dyskinesia: Insights from multimodal imaging and immunohistochemistry in non-human primates. Neuroimage. PMID 30102999 DOI: 10.1016/j.neuroimage.2018.08.016  0.56
2018 Cromwell HC, Tremblay L, Schultz W. Neural encoding of choice during a delayed response task in primate striatum and orbitofrontal cortex. Experimental Brain Research. PMID 29610950 DOI: 10.1007/s00221-018-5253-z  0.96
2018 Prange S, Pagonabarraga J, Krack P, Kulisevsky J, Sgambato V, Tremblay L, Thobois S, Broussolle E. Historical crossroads in the conceptual delineation of apathy in Parkinson's disease. Brain : a Journal of Neurology. PMID 29329378 DOI: 10.1093/brain/awx362  0.48
2017 Météreau E, Beaudoin-Gobert M, Duperrier S, Thobois S, Tremblay L, Sgambato-Faure V. Diffusion tensor imaging marks dopaminergic and serotonergic lesions in the Parkinsonian monkey. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 29076602 DOI: 10.1002/mds.27201  0.56
2017 Thobois S, Prange S, Sgambato-Faure V, Tremblay L, Broussolle E. Imaging the Etiology of Apathy, Anxiety, and Depression in Parkinson's Disease: Implication for Treatment. Current Neurology and Neuroscience Reports. 17: 76. PMID 28822071 DOI: 10.1007/s11910-017-0788-0  0.56
2017 Sgambato-Faure V, Billard T, Météreau E, Duperrier S, Fieux S, Costes N, Tremblay L, Zimmer L. Characterization and Reliability of [(18)F]2FNQ1P in Cynomolgus Monkeys as a PET Radiotracer for Serotonin 5-HT6 Receptors. Frontiers in Pharmacology. 8: 471. PMID 28769801 DOI: 10.3389/fphar.2017.00471  0.56
2017 Sgambato-Faure V, Tremblay L. Dopamine and serotonin modulation of motor and non-motor functions of the non-human primate striato-pallidal circuits in normal and pathological states. Journal of Neural Transmission (Vienna, Austria : 1996). PMID 28176009 DOI: 10.1007/s00702-017-1693-z  0.56
2016 Galineau L, Kas A, Worbe Y, Chaigneau M, Herard AS, Guillermier M, Delzescaux T, Féger J, Hantraye P, Tremblay L. Cortical areas involved in behavioral expression of external pallidum dysfunctions: A PET imaging study in non-human primates. Neuroimage. PMID 27989846 DOI: 10.1016/j.neuroimage.2016.10.039  0.8
2016 Maillet A, Krack P, Lhommée E, Météreau E, Klinger H, Favre E, Le Bars D, Schmitt E, Bichon A, Pelissier P, Fraix V, Castrioto A, Sgambato-Faure V, Broussolle E, Tremblay L, et al. The prominent role of serotonergic degeneration in apathy, anxiety and depression in de novo Parkinson's disease. Brain : a Journal of Neurology. PMID 27538418 DOI: 10.1093/brain/aww162  0.56
2016 Saga Y, Richard A, Sgambato-Faure V, Hoshi E, Tobler PN, Tremblay L. Ventral Pallidum Encodes Contextual Information and Controls Aversive Behaviors. Cerebral Cortex (New York, N.Y. : 1991). PMID 27114173 DOI: 10.1093/cercor/bhw107  0.56
2016 Ballanger B, Beaudoin-Gobert M, Neumane S, Epinat J, Metereau E, Duperrier S, Broussolle E, Thobois S, Bonnefoi F, Tourvielle C, Lavenne F, Costes N, Lebars D, Zimmer L, Sgambato-Faure V, ... Tremblay L, et al. Imaging Dopamine and Serotonin Systems on MPTP Monkeys: A Longitudinal PET Investigation of Compensatory Mechanisms. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 1577-89. PMID 26843639 DOI: 10.1523/JNEUROSCI.2010-15.2016  0.8
2016 Sgambato-Faure V, Worbe Y, Epinat J, Féger J, Tremblay L. Cortico-basal ganglia circuits involved in different motivation disorders in non-human primates. Brain Structure & Function. 221: 345-64. PMID 25304400 DOI: 10.1007/s00429-014-0911-9  0.8
2015 Beaudoin-Gobert M, Tremblay L, Sgambato-Faure V. [An implication of serotonergic fibers which goes beyond Levodopa-induced dyskinesia]. MéDecine Sciences : M/S. 31: 956-9. PMID 26576599 DOI: 10.1051/medsci/20153111006  0.56
2015 Beaudoin-Gobert M, Epinat J, Météreau E, Duperrier S, Neumane S, Ballanger B, Lavenne F, Liger F, Tourvielle C, Bonnefoi F, Costes N, Bars DL, Broussolle E, Thobois S, Tremblay L, et al. Behavioural impact of a double dopaminergic and serotonergic lesion in the non-human primate. Brain : a Journal of Neurology. 138: 2632-47. PMID 26117365 DOI: 10.1093/brain/awv183  0.8
2015 Tremblay L, Worbe Y, Thobois S, Sgambato-Faure V, Féger J. Selective dysfunction of basal ganglia subterritories: From movement to behavioral disorders. Movement Disorders : Official Journal of the Movement Disorder Society. 30: 1155-70. PMID 25772380 DOI: 10.1002/mds.26199  0.8
2015 Durand E, Petit O, Tremblay L, Zimmer C, Sgambato-Faure V, Chassain C, Laurent M, Pereira B, Silberberg C, Durif F. Social behavioral changes in MPTP-treated monkey model of Parkinson's disease. Frontiers in Behavioral Neuroscience. 9: 42. PMID 25767440 DOI: 10.3389/fnbeh.2015.00042  0.72
2015 Becker G, Colomb J, Sgambato-Faure V, Tremblay L, Billard T, Zimmer L. Preclinical evaluation of [18F]2FNQ1P as the first fluorinated serotonin 5-HT6 radioligand for PET imaging. European Journal of Nuclear Medicine and Molecular Imaging. 42: 495-502. PMID 25331460 DOI: 10.1007/s00259-014-2936-y  0.72
2013 Saga Y, Hashimoto M, Tremblay L, Tanji J, Hoshi E. Representation of spatial- and object-specific behavioral goals in the dorsal globus pallidus of monkeys during reaching movement. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 16360-71. PMID 24107966 DOI: 10.1523/JNEUROSCI.1187-13.2013  0.72
2013 Ballanger B, Tremblay L, Sgambato-Faure V, Beaudoin-Gobert M, Lavenne F, Le Bars D, Costes N. A multi-atlas based method for automated anatomical Macaca fascicularis brain MRI segmentation and PET kinetic extraction. Neuroimage. 77: 26-43. PMID 23537938 DOI: 10.1016/j.neuroimage.2013.03.029  0.56
2013 Worbe Y, Sgambato-Faure V, Epinat J, Chaigneau M, Tandé D, François C, Féger J, Tremblay L. Towards a primate model of Gilles de la Tourette syndrome: anatomo-behavioural correlation of disorders induced by striatal dysfunction. Cortex; a Journal Devoted to the Study of the Nervous System and Behavior. 49: 1126-40. PMID 23040317 DOI: 10.1016/j.cortex.2012.08.020  0.8
2012 Neumane S, Mounayar S, Jan C, Epinat J, Ballanger B, Costes N, Féger J, Thobois S, François C, Sgambato-Faure V, Tremblay L. Effects of dopamine and serotonin antagonist injections into the striatopallidal complex of asymptomatic MPTP-treated monkeys. Neurobiology of Disease. 48: 27-39. PMID 22728661 DOI: 10.1016/j.nbd.2012.06.002  0.8
2012 Ballanger B, Klinger H, Eche J, Lerond J, Vallet AE, Le Bars D, Tremblay L, Sgambato-Faure V, Broussolle E, Thobois S. Role of serotonergic 1A receptor dysfunction in depression associated with Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 27: 84-9. PMID 21994070 DOI: 10.1002/mds.23895  0.72
2011 Worbe Y, Epinat J, Féger J, Tremblay L. Discontinuous long-train stimulation in the anterior striatum in monkeys induces abnormal behavioral states. Cerebral Cortex (New York, N.Y. : 1991). 21: 2733-41. PMID 21508304 DOI: 10.1093/cercor/bhr063  0.8
2010 Worbe Y, Gerardin E, Hartmann A, Valabrégue R, Chupin M, Tremblay L, Vidailhet M, Colliot O, Lehéricy S. Distinct structural changes underpin clinical phenotypes in patients with Gilles de la Tourette syndrome. Brain : a Journal of Neurology. 133: 3649-60. PMID 20959309 DOI: 10.1093/brain/awq293  0.72
2010 Thobois S, Ardouin C, Lhommée E, Klinger H, Lagrange C, Xie J, Fraix V, Coelho Braga MC, Hassani R, Kistner A, Juphard A, Seigneuret E, Chabardes S, Mertens P, Polo G, ... ... Tremblay L, et al. Non-motor dopamine withdrawal syndrome after surgery for Parkinson's disease: predictors and underlying mesolimbic denervation. Brain : a Journal of Neurology. 133: 1111-27. PMID 20237128 DOI: 10.1093/brain/awq032  0.72
2009 Féger J, Worbe Y, Galineau L, Tremblay L. [Basal ganglia and psychiatric disorders: an experimental validation]. Annales Pharmaceutiques FrançAises. 67: 320-34. PMID 19695368 DOI: 10.1016/j.pharma.2009.06.003  0.8
2009 Worbe Y, Baup N, Grabli D, Chaigneau M, Mounayar S, McCairn K, Féger J, Tremblay L. Behavioral and movement disorders induced by local inhibitory dysfunction in primate striatum. Cerebral Cortex (New York, N.Y. : 1991). 19: 1844-56. PMID 19068490 DOI: 10.1093/cercor/bhn214  0.72
2008 Boulet S, Mounayar S, Poupard A, Bertrand A, Jan C, Pessiglione M, Hirsch EC, Feuerstein C, François C, Féger J, Savasta M, Tremblay L. Behavioral recovery in MPTP-treated monkeys: neurochemical mechanisms studied by intrastriatal microdialysis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 9575-84. PMID 18799689 DOI: 10.1523/JNEUROSCI.3465-08.2008  0.8
2008 Baup N, Grabli D, Karachi C, Mounayar S, François C, Yelnik J, Féger J, Tremblay L. High-frequency stimulation of the anterior subthalamic nucleus reduces stereotyped behaviors in primates. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 8785-8. PMID 18753380 DOI: 10.1523/JNEUROSCI.2384-08.2008  0.8
2007 Mounayar S, Boulet S, Tandé D, Jan C, Pessiglione M, Hirsch EC, Féger J, Savasta M, François C, Tremblay L. A new model to study compensatory mechanisms in MPTP-treated monkeys exhibiting recovery. Brain : a Journal of Neurology. 130: 2898-914. PMID 17855373 DOI: 10.1093/brain/awm208  0.8
2006 Lehéricy S, Bardinet E, Tremblay L, Van de Moortele PF, Pochon JB, Dormont D, Kim DS, Yelnik J, Ugurbil K. Motor control in basal ganglia circuits using fMRI and brain atlas approaches. Cerebral Cortex (New York, N.Y. : 1991). 16: 149-61. PMID 15858164 DOI: 10.1093/cercor/bhi089  0.72
2005 Pessiglione M, Czernecki V, Pillon B, Dubois B, Schüpbach M, Agid Y, Tremblay L. An effect of dopamine depletion on decision-making: the temporal coupling of deliberation and execution. Journal of Cognitive Neuroscience. 17: 1886-96. PMID 16356326 DOI: 10.1162/089892905775008661  0.72
2005 Hoshi E, Tremblay L, Féger J, Carras PL, Strick PL. The cerebellum communicates with the basal ganglia. Nature Neuroscience. 8: 1491-3. PMID 16205719 DOI: 10.1038/nn1544  0.72
2005 Pessiglione M, Guehl D, Rolland AS, François C, Hirsch EC, Féger J, Tremblay L. Thalamic neuronal activity in dopamine-depleted primates: evidence for a loss of functional segregation within basal ganglia circuits. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 1523-31. PMID 15703406 DOI: 10.1523/JNEUROSCI.4056-04.2005  0.8
2005 Karachi C, Yelnik J, Tandé D, Tremblay L, Hirsch EC, François C. The pallidosubthalamic projection: an anatomical substrate for nonmotor functions of the subthalamic nucleus in primates. Movement Disorders : Official Journal of the Movement Disorder Society. 20: 172-80. PMID 15382210 DOI: 10.1002/mds.20302  0.44
2004 Gerardin E, Pochon JB, Poline JB, Tremblay L, Van de Moortele PF, Levy R, Dubois B, Le Bihan D, Lehéricy S. Distinct striatal regions support movement selection, preparation and execution. Neuroreport. 15: 2327-31. PMID 15640749 DOI: 10.1097/00001756-200410250-00005  0.72
2004 François C, Grabli D, McCairn K, Jan C, Karachi C, Hirsch EC, Féger J, Tremblay L. Behavioural disorders induced by external globus pallidus dysfunction in primates II. Anatomical study. Brain : a Journal of Neurology. 127: 2055-70. PMID 15292054 DOI: 10.1093/brain/awh239  0.72
2004 Grabli D, McCairn K, Hirsch EC, Agid Y, Féger J, François C, Tremblay L. Behavioural disorders induced by external globus pallidus dysfunction in primates: I. Behavioural study. Brain : a Journal of Neurology. 127: 2039-54. PMID 15292053 DOI: 10.1093/brain/awh220  0.72
2004 Pessiglione M, Guehl D, Jan C, François C, Hirsch EC, Féger J, Tremblay L. Disruption of self-organized actions in monkeys with progressive MPTP-induced parkinsonism: II. Effects of reward preference. The European Journal of Neuroscience. 19: 437-46. PMID 14725638  0.8
2004 Pessiglione M, Guehl D, Hirsch EC, Féger J, Tremblay L. Disruption of self-organized actions in monkeys with progressive MPTP-induced parkinsonism. I. Effects of task complexity. The European Journal of Neuroscience. 19: 426-36. PMID 14725637  0.8
2003 Jan C, Pessiglione M, Tremblay L, Tandé D, Hirsch EC, François C. Quantitative analysis of dopaminergic loss in relation to functional territories in MPTP-treated monkeys. The European Journal of Neuroscience. 18: 2082-6. PMID 14622241  0.44
2003 Rousselet E, Joubert C, Callebert J, Parain K, Tremblay L, Orieux G, Launay JM, Cohen-Salmon C, Hirsch EC. Behavioral changes are not directly related to striatal monoamine levels, number of nigral neurons, or dose of parkinsonian toxin MPTP in mice Neurobiology of Disease. 14: 218-228. PMID 14572444 DOI: 10.1016/S0969-9961(03)00108-6  0.72
2003 Guehl D, Pessiglione M, François C, Yelnik J, Hirsch EC, Féger J, Tremblay L. Tremor-related activity of neurons in the 'motor' thalamus: changes in firing rate and pattern in the MPTP vervet model of parkinsonism. The European Journal of Neuroscience. 17: 2388-400. PMID 12814370  0.8
2003 Schultz W, Tremblay L, Hollerman JR. Changes in behavior-related neuronal activity in the striatum during learning. Trends in Neurosciences. 26: 321-8. PMID 12798602 DOI: 10.1016/S0166-2236(03)00122-X  0.72
2003 Pessiglione M, Guehl D, Agid Y, Hirsch EC, Féger J, Tremblay L. Impairment of context-adapted movement selection in a primate model of presymptomatic Parkinson's disease. Brain : a Journal of Neurology. 126: 1392-408. PMID 12764060 DOI: 10.1093/brain/awg139  0.72
2002 Périer C, Tremblay L, Féger J, Hirsch EC. Behavioral consequences of bicuculline injection in the subthalamic nucleus and the zona incerta in rat. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 8711-9. PMID 12351746  0.8
2002 Tremblay L, Gettner SN, Olson CR. Neurons with object-centered spatial selectivity in macaque SEF: do they represent locations or rules? Journal of Neurophysiology. 87: 333-50. PMID 11784754  0.72
2001 Watanabe M, Cromwell HC, Tremblay L, Hollerman JR, Hikosaka K, Schultz W. Behavioral reactions reflecting differential reward expectations in monkeys. Experimental Brain Research. 140: 511-8. PMID 11685405 DOI: 10.1007/s002210100856  0.72
2000 Hollerman JR, Tremblay L, Schultz W. Involvement of basal ganglia and orbitofrontal cortex in goal-directed behavior. Progress in Brain Research. 126: 193-215. PMID 11105648 DOI: 10.1016/S0079-6123(00)26015-9  0.72
2000 Olson CR, Tremblay L. Macaque supplementary eye field neurons encode object-centered locations relative to both continuous and discontinuous objects. Journal of Neurophysiology. 83: 2392-411. PMID 10758141  0.72
2000 Tremblay L, Schultz W. Modifications of reward expectation-related neuronal activity during learning in primate orbitofrontal cortex. Journal of Neurophysiology. 83: 1877-85. PMID 10758099  0.72
2000 Tremblay L, Schultz W. Reward-related neuronal activity during go-nogo task performance in primate orbitofrontal cortex. Journal of Neurophysiology. 83: 1864-76. PMID 10758098  0.72
2000 Schultz W, Tremblay L, Hollerman JR. Reward processing in primate orbitofrontal cortex and basal ganglia. Cerebral Cortex (New York, N.Y. : 1991). 10: 272-84. PMID 10731222  0.72
1999 Tremblay L, Schultz W. Relative reward preference in primate orbitofrontal cortex. Nature. 398: 704-8. PMID 10227292 DOI: 10.1038/19525  0.96
1998 Tremblay L, Hollerman JR, Schultz W. Modifications of reward expectation-related neuronal activity during learning in primate striatum. Journal of Neurophysiology. 80: 964-77. PMID 9705482  0.72
1998 Hollerman JR, Tremblay L, Schultz W. Influence of reward expectation on behavior-related neuronal activity in primate striatum. Journal of Neurophysiology. 80: 947-63. PMID 9705481  0.72
1998 Schultz W, Tremblay L, Hollerman JR. Reward prediction in primate basal ganglia and frontal cortex. Neuropharmacology. 37: 421-9. PMID 9704983 DOI: 10.1016/S0028-3908(98)00071-9  0.72
1995 Matsumura M, Tremblay L, Richard H, Filion M. Activity of pallidal neurons in the monkey during dyskinesia induced by injection of bicuculline in the external pallidum. Neuroscience. 65: 59-70. PMID 7753408  1
1994 Filion M, Tremblay L, Matsumura M, Richard H. [Dynamic focusing of informational convergence in basal ganglia]. Revue Neurologique. 150: 627-33. PMID 7754300  1
1993 Percheron G, Filion M, Tremblay L, Fénelon G, François C, Yelnik J. The role of the medial pallidum in the pathophysiology of akinesia in primates. Advances in Neurology. 60: 84-7. PMID 8420221  1
1993 Glowinski J, Kemel ML, Desban M, Gauchy C, Lavielle S, Chassaing G, Beaujouan JC, Tremblay L. Distinct presynaptic control of dopamine release in striosomal- and matrix-enriched areas of the rat striatum by selective agonists of NK1, NK2 and NK3 tachykinin receptors. Regulatory Peptides. 46: 124-8. PMID 7692480  0.8
1992 L'Abbé D, Tremblay L, Filion M, Busque L, Goldman M, Décary F, Chartrand P. Alloimmunization to platelet antigen HPA-1a (PIA1) is strongly associated with both HLA-DRB3*0101 and HLA-DQB1*0201. Human Immunology. 34: 107-14. PMID 1358865  1
1992 Tremblay L, Kemel ML, Desban M, Gauchy C, Glowinski J. Distinct presynaptic control of dopamine release in striosomal- and matrix-enriched areas of the rat striatum by selective agonists of NK1, NK2, and NK3 tachykinin receptors. Proceedings of the National Academy of Sciences of the United States of America. 89: 11214-8. PMID 1280822  0.8
1991 Filion M, Tremblay L, Bédard PJ. Effects of dopamine agonists on the spontaneous activity of globus pallidus neurons in monkeys with MPTP-induced parkinsonism. Brain Research. 547: 152-61. PMID 1677608  1
1991 Filion M, Tremblay L. Abnormal spontaneous activity of globus pallidus neurons in monkeys with MPTP-induced parkinsonism. Brain Research. 547: 142-51. PMID 1677607  1
1989 Tremblay L, Filion M, Bédard PJ. Responses of pallidal neurons to striatal stimulation in monkeys with MPTP-induced parkinsonism. Brain Research. 498: 17-33. PMID 2790469  1
1989 Tremblay L, Filion M. Responses of pallidal neurons to striatal stimulation in intact waking monkeys. Brain Research. 498: 1-16. PMID 2790460  1
1988 Filion M, Tremblay L, Bédard PJ. Abnormal influences of passive limb movement on the activity of globus pallidus neurons in parkinsonian monkeys. Brain Research. 444: 165-76. PMID 3359286  1
1987 Bédard PJ, Tremblay LE, Barbeau H, Filion M, Maheux R, Richards CL, DiPaolo T. Action of 5-hydroxytryptamine, substance P, thyrotropin-releasing hormone and clonidine on motoneurone excitability. The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. 14: 506-9. PMID 2445457  1
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