T Michael Underhill - Publications

Affiliations: 
The University of Western Ontario (Canada) 
Area:
Cell Biology, Animal Physiology Biology

54 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Arostegui M, Underhill TM. Murine Limb Bud Organ Cultures for Studying Musculoskeletal Development. Methods in Molecular Biology (Clifton, N.J.). 2230: 115-137. PMID 33197012 DOI: 10.1007/978-1-0716-1028-2_8  0.327
2020 Abbasi S, Sinha S, Labit E, Rosin NL, Yoon G, Rahmani W, Jaffer A, Sharma N, Hagner A, Shah P, Arora R, Yoon J, Islam A, Uchida A, Chang CK, ... ... Underhill TM, et al. Distinct Regulatory Programs Control the Latent Regenerative Potential of Dermal Fibroblasts during Wound Healing. Cell Stem Cell. PMID 32755548 DOI: 10.1016/J.Stem.2020.07.008  0.354
2020 Soliman H, Paylor B, Scott RW, Lemos DR, Chang C, Arostegui M, Low M, Lee C, Fiore D, Braghetta P, Pospichalova V, Barkauskas CE, Korinek V, Rampazzo A, MacLeod K, ... Underhill TM, et al. Pathogenic Potential of Hic1-Expressing Cardiac Stromal Progenitors. Cell Stem Cell. PMID 31978365 DOI: 10.1016/J.Stem.2019.12.008  0.301
2019 Scott RW, Arostegui M, Schweitzer R, Rossi FMV, Underhill TM. Hic1 Defines Quiescent Mesenchymal Progenitor Subpopulations with Distinct Functions and Fates in Skeletal Muscle Regeneration. Cell Stem Cell. 25: 797-813.e9. PMID 31809738 DOI: 10.1016/J.Stem.2019.11.004  0.334
2019 Lo BC, Canals Hernaez D, Scott RW, Hughes MR, Shin SB, Underhill TM, Takei F, McNagny KM. The Transcription Factor RORα Preserves ILC3 Lineage Identity and Function during Chronic Intestinal Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 31676672 DOI: 10.4049/Jimmunol.1900781  0.407
2019 Patel N, Wang J, Shiozawa K, Jones KB, Zhang Y, Prokop JW, Davenport GG, Nihira NT, Hao Z, Wong D, Brandsmeier L, Meadows SK, Sampaio AV, Werff RV, Endo M, ... ... Underhill TM, et al. HDAC2 Regulates Site-Specific Acetylation of MDM2 and Its Ubiquitination Signaling in Tumor Suppression. Iscience. 13: 43-54. PMID 30818224 DOI: 10.1016/J.Isci.2019.02.008  0.371
2019 Cait J, Hughes MR, Zeglinski MR, Chan AW, Osterhof S, Scott RW, Canals Hernaez D, Cait A, Vogl AW, Bernatchez P, Underhill TM, Granville DJ, Murphy TH, Roskelley CD, McNagny KM. Podocalyxin is required for maintaining blood-brain barrier function during acute inflammation. Proceedings of the National Academy of Sciences of the United States of America. PMID 30787191 DOI: 10.1073/Pnas.1814766116  0.326
2018 Wang Y, Chen SY, Colborne S, Lambert G, Shin CY, Dos Santos N, Orlando KA, Lang JD, Hendricks WPD, Bally MB, Karnezis AN, Hass R, Underhill TM, Morin GB, Trent JM, et al. Histone deacetylase inhibitors synergizes with catalytic inhibitors of EZH2 to exhibit anti-tumor activity in small cell carcinoma of the ovary, hypercalcemic type. Molecular Cancer Therapeutics. PMID 30232145 DOI: 10.1158/1535-7163.Mct-18-0348  0.336
2018 Burrows K, Antignano F, Chenery A, Bramhall M, Korinek V, Underhill TM, Zaph C. HIC1 links retinoic acid signalling to group 3 innate lymphoid cell-dependent regulation of intestinal immunity and homeostasis. Plos Pathogens. 14. PMID 29470558 DOI: 10.1371/Journal.Ppat.1006869  0.325
2018 Laporte AN, Poulin NM, Lorzadeh A, Wang XQ, werff RV, Barrott JJ, Moska M, Hughes C, Morin G, Jones KB, Hirst M, Underhill TM, Nielsen TO. Abstract A13: Genome-wide transcriptional analysis of HDAC inhibition-induced apoptosis in synovial sarcoma Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Sarcomas17-A13  0.354
2017 Laporte AN, Poulin NM, Barrott JJ, Wang XQ, Lorzadeh A, Vander Werff R, Jones KB, Underhill TM, Nielsen TO. Death by HDAC inhibition in synovial sarcoma cells. Molecular Cancer Therapeutics. PMID 28878027 DOI: 10.1158/1535-7163.Mct-17-0397  0.347
2017 Higashihori N, Lehnertz B, Sampaio A, Underhill TM, Rossi F, Richman JM. Methyltransferase G9A Regulates Osteogenesis via Twist Gene Repression. Journal of Dental Research. 96: 1136-1144. PMID 28644763 DOI: 10.1177/0022034517716438  0.307
2017 Hassan HM, Kolendowski B, Isovic M, Bose K, Dranse HJ, Sampaio AV, Underhill TM, Torchia J. Regulation of Active DNA Demethylation through RAR-Mediated Recruitment of a TET/TDG Complex. Cell Reports. 19: 1685-1697. PMID 28538185 DOI: 10.1016/J.Celrep.2017.05.007  0.446
2017 Laporte AN, Barrott JJ, Yao RJ, Poulin NM, Brodin BA, Jones KB, Underhill TM, Nielsen TO. HDAC and Proteasome Inhibitors Synergize to Activate Pro-Apoptotic Factors in Synovial Sarcoma. Plos One. 12: e0169407. PMID 28056055 DOI: 10.1371/Journal.Pone.0169407  0.319
2016 Scott RW, Underhill TM. Methods and Strategies for Lineage Tracing of Mesenchymal Progenitor Cells. Methods in Molecular Biology (Clifton, N.J.). 1416: 171-203. PMID 27236672 DOI: 10.1007/978-1-4939-3584-0_10  0.341
2015 Garside VC, Cullum R, Alder O, Lu DY, Vander Werff R, Bilenky M, Zhao Y, Jones SJ, Marra MA, Underhill TM, Hoodless PA. SOX9 modulates the expression of key transcription factors required for heart valve development. Development (Cambridge, England). PMID 26525672 DOI: 10.1242/Dev.125252  0.371
2015 Racacho L, Byrnes AM, MacDonald H, Dranse HJ, Nikkel SM, Allanson J, Rosser E, Underhill TM, Bulman DE. Two novel disease-causing variants in BMPR1B are associated with brachydactyly type A1. European Journal of Human Genetics : Ejhg. 23: 1640-5. PMID 25758993 DOI: 10.1038/Ejhg.2015.38  0.323
2014 Lehnertz B, Pabst C, Su L, Miller M, Liu F, Yi L, Zhang R, Krosl J, Yung E, Kirschner J, Rosten P, Underhill TM, Jin J, Hébert J, Sauvageau G, et al. The methyltransferase G9a regulates HoxA9-dependent transcription in AML. Genes & Development. 28: 317-27. PMID 24532712 DOI: 10.1101/Gad.236794.113  0.328
2014 Underhill TM, Dranse HJ, Hoffman LM. Analysis of chondrogenesis using micromass cultures of limb mesenchyme. Methods in Molecular Biology (Clifton, N.J.). 1130: 251-65. PMID 24482179 DOI: 10.1007/978-1-62703-989-5_19  0.322
2013 Chenery A, Burrows K, Antignano F, Underhill TM, Petkovich M, Zaph C. The retinoic acid-metabolizing enzyme Cyp26b1 regulates CD4 T cell differentiation and function. Plos One. 8: e72308. PMID 23991089 DOI: 10.1371/Journal.Pone.0072308  0.354
2012 Su L, Sampaio AV, Jones KB, Pacheco M, Goytain A, Lin S, Poulin N, Yi L, Rossi FM, Kast J, Capecchi MR, Underhill TM, Nielsen TO. Deconstruction of the SS18-SSX fusion oncoprotein complex: insights into disease etiology and therapeutics. Cancer Cell. 21: 333-47. PMID 22439931 DOI: 10.1016/J.Ccr.2012.01.010  0.376
2012 Lemos DR, Paylor B, Chang C, Sampaio A, Underhill TM, Rossi FM. Functionally convergent white adipogenic progenitors of different lineages participate in a diffused system supporting tissue regeneration. Stem Cells (Dayton, Ohio). 30: 1152-62. PMID 22415977 DOI: 10.1002/Stem.1082  0.35
2011 Bond SR, Lau A, Penuela S, Sampaio AV, Underhill TM, Laird DW, Naus CC. Pannexin 3 is a novel target for Runx2, expressed by osteoblasts and mature growth plate chondrocytes. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 2911-22. PMID 21915903 DOI: 10.1002/Jbmr.509  0.404
2011 Dranse HJ, Sampaio AV, Petkovich M, Underhill TM. Genetic deletion of Cyp26b1 negatively impacts limb skeletogenesis by inhibiting chondrogenesis. Journal of Cell Science. 124: 2723-34. PMID 21807937 DOI: 10.1242/Jcs.084699  0.483
2010 Karamboulas K, Dranse HJ, Underhill TM. Regulation of BMP-dependent chondrogenesis in early limb mesenchyme by TGFbeta signals. Journal of Cell Science. 123: 2068-76. PMID 20501701 DOI: 10.1242/Jcs.062901  0.468
2010 James CG, Stanton LA, Agoston H, Ulici V, Underhill TM, Beier F. Genome-wide analyses of gene expression during mouse endochondral ossification. Plos One. 5: e8693. PMID 20084171 DOI: 10.1371/Journal.Pone.0008693  0.397
2010 Ye M, Berry-Wynne KM, Asai-Coakwell M, Sundaresan P, Footz T, French CR, Abitbol M, Fleisch VC, Corbett N, Allison WT, Drummond G, Walter MA, Underhill TM, Waskiewicz AJ, Lehmann OJ. Mutation of the bone morphogenetic protein GDF3 causes ocular and skeletal anomalies. Human Molecular Genetics. 19: 287-98. PMID 19864492 DOI: 10.1093/Hmg/Ddp496  0.367
2009 Bragdon B, Thinakaran S, Bonor J, Underhill TM, Petersen NO, Nohe A. FRET reveals novel protein-receptor interaction of bone morphogenetic proteins receptors and adaptor protein 2 at the cell surface. Biophysical Journal. 97: 1428-35. PMID 19720031 DOI: 10.1016/J.Bpj.2009.05.061  0.39
2009 Widenmaier SB, Sampaio AV, Underhill TM, McIntosh CH. Noncanonical activation of Akt/protein kinase B in {beta}-cells by the incretin hormone glucose-dependent insulinotropic polypeptide. The Journal of Biological Chemistry. 284: 10764-73. PMID 19233842 DOI: 10.1074/Jbc.M809116200  0.317
2009 Welch ID, Cowan MF, Beier F, Underhill TM. The retinoic acid binding protein CRABP2 is increased in murine models of degenerative joint disease. Arthritis Research & Therapy. 11: R14. PMID 19173746 DOI: 10.1186/ar2604  0.31
2009 Asai-Coakwell M, French CR, Ye M, Garcha K, Bigot K, Perera AG, Staehling-Hampton K, Mema SC, Chanda B, Mushegian A, Bamforth S, Doschak MR, Li G, Dobbs MB, Giampietro PF, ... ... Underhill TM, et al. Incomplete penetrance and phenotypic variability characterize Gdf6-attributable oculo-skeletal phenotypes. Human Molecular Genetics. 18: 1110-21. PMID 19129173 DOI: 10.1093/Hmg/Ddp008  0.387
2008 Stuart HC, Jia Z, Messenberg A, Joshi B, Underhill TM, Moukhles H, Nabi IR. Localized Rho GTPase activation regulates RNA dynamics and compartmentalization in tumor cell protrusions. The Journal of Biological Chemistry. 283: 34785-95. PMID 18845542 DOI: 10.1074/Jbc.M804014200  0.369
2007 Noble BR, Babiuk RP, Clugston RD, Underhill TM, Sun H, Kawaguchi R, Walfish PG, Blomhoff R, Gundersen TE, Greer JJ. Mechanisms of action of the congenital diaphragmatic hernia-inducing teratogen nitrofen. American Journal of Physiology. Lung Cellular and Molecular Physiology. 293: L1079-87. PMID 17704186 DOI: 10.1152/Ajplung.00286.2007  0.303
2007 James CG, Ulici V, Tuckermann J, Underhill TM, Beier F. Expression profiling of Dexamethasone-treated primary chondrocytes identifies targets of glucocorticoid signalling in endochondral bone development. Bmc Genomics. 8: 205. PMID 17603917 DOI: 10.1186/1471-2164-8-205  0.409
2007 Gordon JA, Tye CE, Sampaio AV, Underhill TM, Hunter GK, Goldberg HA. Bone sialoprotein expression enhances osteoblast differentiation and matrix mineralization in vitro. Bone. 41: 462-73. PMID 17572166 DOI: 10.1016/J.Bone.2007.04.191  0.438
2006 James CG, Woods A, Underhill TM, Beier F. The transcription factor ATF3 is upregulated during chondrocyte differentiation and represses cyclin D1 and A gene transcription. Bmc Molecular Biology. 7: 30. PMID 16984628 DOI: 10.1186/1471-2199-7-30  0.402
2006 Hoffman LM, Garcha K, Karamboulas K, Cowan MF, Drysdale LM, Horton WA, Underhill TM. BMP action in skeletogenesis involves attenuation of retinoid signaling. The Journal of Cell Biology. 174: 101-13. PMID 16818722 DOI: 10.1083/Jcb.200604150  0.508
2005 James CG, Appleton CT, Ulici V, Underhill TM, Beier F. Microarray analyses of gene expression during chondrocyte differentiation identifies novel regulators of hypertrophy. Molecular Biology of the Cell. 16: 5316-33. PMID 16135533 DOI: 10.1091/Mbc.E05-01-0084  0.477
2005 Nohe A, Keating E, Underhill TM, Knaus P, Petersen NO. Dynamics and interaction of caveolin-1 isoforms with BMP-receptors. Journal of Cell Science. 118: 643-50. PMID 15657086 DOI: 10.1242/Jcs.01402  0.37
2004 Stanton LA, Sabari S, Sampaio AV, Underhill TM, Beier F. p38 MAP kinase signalling is required for hypertrophic chondrocyte differentiation. The Biochemical Journal. 378: 53-62. PMID 14594450 DOI: 10.1042/Bj20030874  0.471
2003 Stanton LA, Underhill TM, Beier F. MAP kinases in chondrocyte differentiation. Developmental Biology. 263: 165-75. PMID 14597193 DOI: 10.1016/S0012-1606(03)00321-X  0.415
2003 Weston AD, Hoffman LM, Underhill TM. Revisiting the role of retinoid signaling in skeletal development. Birth Defects Research. Part C, Embryo Today : Reviews. 69: 156-73. PMID 12955859 DOI: 10.1002/Bdrc.10010  0.734
2003 Wongtrakool C, Malpel S, Gorenstein J, Sedita J, Ramirez MI, Underhill TM, Cardoso WV. Down-regulation of retinoic acid receptor alpha signaling is required for sacculation and type I cell formation in the developing lung. The Journal of Biological Chemistry. 278: 46911-8. PMID 12947094 DOI: 10.1074/Jbc.M307977200  0.425
2003 Brown K, Chen Y, Underhill TM, Mymryk JS, Torchia J. The coactivator p/CIP/SRC-3 facilitates retinoic acid receptor signaling via recruitment of GCN5. The Journal of Biological Chemistry. 278: 39402-12. PMID 12885766 DOI: 10.1074/Jbc.M307832200  0.366
2003 Nohe A, Keating E, Underhill TM, Knaus P, Petersen NO. Effect of the distribution and clustering of the type I A BMP receptor (ALK3) with the type II BMP receptor on the activation of signalling pathways. Journal of Cell Science. 116: 3277-84. PMID 12829744 DOI: 10.1242/Jcs.00519  0.447
2003 Weston AD, Sampaio AV, Ridgeway AG, Underhill TM. Inhibition of p38 MAPK signaling promotes late stages of myogenesis. Journal of Cell Science. 116: 2885-93. PMID 12771182 DOI: 10.1242/Jcs.00525  0.699
2003 Hoffman LM, Weston AD, Underhill TM. Molecular mechanisms regulating chondroblast differentiation. The Journal of Bone and Joint Surgery. American Volume. 85: 124-32. PMID 12721355 DOI: 10.2106/00004623-200300002-00017  0.712
2003 Weston AD, Blumberg B, Underhill TM. Active repression by unliganded retinoid receptors in development: less is sometimes more. The Journal of Cell Biology. 161: 223-8. PMID 12719467 DOI: 10.1083/Jcb.200211117  0.711
2002 Weston AD, Chandraratna RA, Torchia J, Underhill TM. Requirement for RAR-mediated gene repression in skeletal progenitor differentiation. The Journal of Cell Biology. 158: 39-51. PMID 12105181 DOI: 10.1083/Jcb.200112029  0.746
2001 Underhill TM, Sampaio AV, Weston AD. Retinoid signalling and skeletal development. Novartis Foundation Symposium. 232: 171-85; discussion 1. PMID 11277079 DOI: 10.1007/978-1-59259-736-9_10  0.736
2000 Weston AD, Underhill TM. Analysis of Nedd4 expression during skeletal development in the mouse limb. Mechanisms of Development. 94: 247-50. PMID 10842081 DOI: 10.1016/S0925-4773(00)00299-9  0.706
2000 Weston AD, Rosen V, Chandraratna RA, Underhill TM. Regulation of skeletal progenitor differentiation by the BMP and retinoid signaling pathways. The Journal of Cell Biology. 148: 679-90. PMID 10684250 DOI: 10.1083/Jcb.148.4.679  0.74
1998 Underhill TM, Weston AD. Retinoids and their receptors in skeletal development. Microscopy Research and Technique. 43: 137-55. PMID 9823001 DOI: 10.1002/(Sici)1097-0029(19981015)43:2<137::Aid-Jemt7>3.0.Co;2-3  0.735
1997 Cash DE, Bock CB, Schughart K, Linney E, Underhill TM. Retinoic acid receptor alpha function in vertebrate limb skeletogenesis: a modulator of chondrogenesis. The Journal of Cell Biology. 136: 445-57. PMID 9015314 DOI: 10.1083/Jcb.136.2.445  0.424
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