Shahin Rafii - Publications

Affiliations: 
Weill Cornell Medical College, New York, NY, United States 
Area:
Cell Biology, Oncology, Animal Physiology Biology

330 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Ishida T, Heck AM, Varnum-Finney B, Dozono S, Nourigat-McKay C, Kraskouskas K, Wellington R, Waltner O, Jackson DL, Delaney C, Rafii S, Bernstein ID, Hadland B. Differentiation latency and dormancy signatures define fetal liver HSCs at single cell resolution. Biorxiv : the Preprint Server For Biology. PMID 37333272 DOI: 10.1101/2023.06.01.543314  0.307
2023 Hagedorn EJ, Perlin JR, Freeman RJ, Wattrus SJ, Han T, Mao C, Kim JW, Fernández-Maestre I, Daily ML, D'Amato C, Fairchild MJ, Riquelme R, Li B, Ragoonanan DAVE, Enkhbayar K, ... ... Rafii S, et al. Transcription factor induction of vascular blood stem cell niches in vivo. Developmental Cell. PMID 37119815 DOI: 10.1016/j.devcel.2023.04.007  0.457
2023 Itkin T, Houghton S, Schreiner R, Lin Y, Badwe CR, Voisin V, Murison A, Seyedhassantehrani N, Kaufmann KB, Garcia-Prat L, Booth GT, Geng F, Liu Y, Gomez-Salinero JM, Shieh JH, ... ... Rafii S, et al. Transcriptional Activation of Regenerative Hematopoiesis via Vascular Niche Sensing. Biorxiv : the Preprint Server For Biology. PMID 37034724 DOI: 10.1101/2023.03.27.534417  0.303
2022 Gomez-Salinero JM, Itkin T, Houghton S, Badwe C, Lin Y, Kalna V, Dufton N, Peghaire CR, Yokoyama M, Wingo M, Lu TM, Li G, Xiang JZ, Hsu YS, Redmond D, ... ... Rafii S, et al. Cooperative ETS Transcription Factors Enforce Adult Endothelial Cell Fate and Cardiovascular Homeostasis. Nature Cardiovascular Research. 1: 882-899. PMID 36713285 DOI: 10.1038/s44161-022-00128-3  0.356
2022 Lai MW, Chow N, Checco A, Kunar B, Redmond D, Rafii S, Rabbany SY. Systems Biology Analysis of Temporal Dynamics That Govern Endothelial Response to Cyclic Stretch. Biomolecules. 12. PMID 36551265 DOI: 10.3390/biom12121837  0.336
2022 Lehmann GL, Ginsberg M, Nolan DJ, Rodríguez C, Martínez-González J, Zeng S, Voigt AP, Mullins RF, Rafii S, Rodriguez-Boulan E, Benedicto I. Retinal Pigment Epithelium-Secreted VEGF-A Induces Alpha-2-Macroglobulin Expression in Endothelial Cells. Cells. 11. PMID 36230937 DOI: 10.3390/cells11192975  0.301
2022 Hadland B, Varnum-Finney B, Dozono S, Dignum T, Nourigat-McKay C, Heck AM, Ishida T, Jackson DL, Itkin T, Butler JM, Rafii S, Trapnell C, Bernstein ID. Engineering a niche supporting hematopoietic stem cell development using integrated single-cell transcriptomics. Nature Communications. 13: 1584. PMID 35332125 DOI: 10.1038/s41467-022-28781-z  0.375
2021 Gomez-Salinero JM, Itkin T, Rafii S. Developmental angiocrine diversification of endothelial cells for organotypic regeneration. Developmental Cell. 56: 3042-3051. PMID 34813766 DOI: 10.1016/j.devcel.2021.10.020  0.327
2021 Howell ED, Yzaguirre AD, Gao P, Lis R, He B, Lakadamyali M, Rafii S, Tan K, Speck NA. Efficient hemogenic endothelial cell specification by RUNX1 is dependent on baseline chromatin accessibility of RUNX1-regulated TGFβ target genes. Genes & Development. 35: 1475-1489. PMID 34675061 DOI: 10.1101/gad.348738.121  0.384
2021 Wingo M, Rafii S. Endothelial reprogramming for vascular regeneration: Past milestones and future directions. Seminars in Cell & Developmental Biology. PMID 34548212 DOI: 10.1016/j.semcdb.2021.09.003  0.401
2021 Dignum T, Varnum-Finney B, Srivatsan SR, Dozono S, Waltner O, Heck AM, Ishida T, Nourigat-McKay C, Jackson DL, Rafii S, Trapnell C, Bernstein ID, Hadland B. Multipotent progenitors and hematopoietic stem cells arise independently from hemogenic endothelium in the mouse embryo. Cell Reports. 36: 109675. PMID 34525376 DOI: 10.1016/j.celrep.2021.109675  0.318
2021 Hisata S, Racanelli AC, Kermani P, Schreiner R, Houghton S, Palikuqi B, Kunar B, Zhou A, McConn K, Capili A, Redmond D, Nolan DJ, Ginsberg M, Ding BS, Martinez FJ, ... ... Rafii S, et al. Reversal of emphysema by restoration of pulmonary endothelial cells. The Journal of Experimental Medicine. 218. PMID 34287647 DOI: 10.1084/jem.20200938  0.345
2021 Adelson RP, Palikuqi B, Weiss Z, Checco A, Schreiner R, Rafii S, Rabbany SY. Morphological characterization of Etv2 explants using fractal analysis and atomic force microscopy. Microvascular Research. 104205. PMID 34146583 DOI: 10.1016/j.mvr.2021.104205  0.336
2021 Lu TM, Barcia Durán JG, Houghton S, Rafii S, Redmond D, Lis R. Human Induced Pluripotent Stem Cell-Derived Brain Endothelial Cells: Current Controversies. Frontiers in Physiology. 12: 642812. PMID 33868008 DOI: 10.3389/fphys.2021.642812  0.354
2021 Barcia Durán JG, Lu T, Houghton S, Geng F, Schreiner R, Xiang J, Rafii S, Redmond D, Lis R. Endothelial Jak3 expression enhances pro-hematopoietic angiocrine function in mice. Communications Biology. 4: 406. PMID 33767339 DOI: 10.1038/s42003-021-01846-3  0.413
2021 Lu TM, Houghton S, Magdeldin T, Durán JGB, Minotti AP, Snead A, Sproul A, Nguyen DT, Xiang J, Fine HA, Rosenwaks Z, Studer L, Rafii S, Agalliu D, Redmond D, et al. Pluripotent stem cell-derived epithelium misidentified as brain microvascular endothelium requires ETS factors to acquire vascular fate. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33542154 DOI: 10.1073/pnas.2016950118  0.394
2020 Palikuqi B, Nguyen DT, Li G, Schreiner R, Pellegata AF, Liu Y, Redmond D, Geng F, Lin Y, Gómez-Salinero JM, Yokoyama M, Zumbo P, Zhang T, Kunar B, Witherspoon M, ... ... Rafii S, et al. Adaptable haemodynamic endothelial cells for organogenesis and tumorigenesis. Nature. PMID 32908310 DOI: 10.1038/S41586-020-2712-Z  0.499
2020 Di Giandomenico S, Kermani P, Mollé N, Yabut MM, Abu-Zeinah GF, Stephens T, Messali N, Brenet F, Rafii S, Scandura JM. Megakaryocyte TGFβ1 Partitions Erythropoiesis into Immature Progenitor/Stem Cells and Maturing Precursors. Blood. PMID 32548608 DOI: 10.1182/Blood.2019003276  0.445
2020 Lehmann GL, Hanke-Gogokhia C, Hu Y, Bareja R, Salfati Z, Ginsberg M, Nolan DJ, Mendez-Huergo SP, Dalotto-Moreno T, Wojcinski A, Ochoa F, Zeng S, Cerliani JP, Panagis L, Zager PJ, ... ... Rafii S, et al. Single-cell profiling reveals an endothelium-mediated immunomodulatory pathway in the eye choroid. The Journal of Experimental Medicine. 217. PMID 32196081 DOI: 10.1084/Jem.20190730  0.441
2020 Pasquier J, Ghiabi P, Chouchane L, Razzouk K, Rafii S, Rafii A. Angiocrine endothelium: from physiology to cancer. Journal of Translational Medicine. 18: 52. PMID 32014047 DOI: 10.1186/S12967-020-02244-9  0.469
2019 Barry DM, McMillan EA, Kunar B, Lis R, Zhang T, Lu T, Daniel E, Yokoyama M, Gomez-Salinero JM, Sureshbabu A, Cleaver O, Di Lorenzo A, Choi ME, Xiang J, Redmond D, ... ... Rafii S, et al. Molecular determinants of nephron vascular specialization in the kidney. Nature Communications. 10: 5705. PMID 31836710 DOI: 10.1038/S41467-019-12872-5  0.381
2019 Barcia Durán JG, Lis R, Rafii S. Haematopoietic stem cell reprogramming and the hope for a universal blood product. Febs Letters. PMID 31725897 DOI: 10.1002/1873-3468.13681  0.425
2019 Rodrigues G, Hoshino A, Kenific CM, Matei IR, Steiner L, Freitas D, Kim HS, Oxley PR, Scandariato I, Casanova-Salas I, Dai J, Badwe CR, Gril B, Tešić Mark M, Dill BD, ... ... Rafii S, et al. Tumour exosomal CEMIP protein promotes cancer cell colonization in brain metastasis. Nature Cell Biology. PMID 31685984 DOI: 10.1038/S41556-019-0404-4  0.347
2019 Hoarau-Véchot J, Touboul C, Halabi N, Blot-Dupin M, Lis R, Abi Khalil C, Rafii S, Rafii A, Pasquier J. Akt-activated endothelium promotes ovarian cancer proliferation through notch activation. Journal of Translational Medicine. 17: 194. PMID 31182109 DOI: 10.1186/S12967-019-1942-Z  0.367
2019 Hagedorn EJ, Perlin JR, Freeman RJ, Mao C, Fernández-Maestre I, Daily ML, D'Amato CR, Wattrus SJ, Han T, Fairchild MJ, Riquelme R, Li B, Redfield SE, Collins SH, Lichtig A, ... ... Rafii S, et al. Transcription Factor Induction of Ectopic Vascular Blood Stem Cell Niches In Vivo Blood. 134: 525-525. DOI: 10.1182/Blood-2019-127219  0.453
2019 Itkin T, Badwe CR, Houghton S, Lin Y, Liu Y, Guo P, Gomez-Salinero JM, Geng F, Shieh J, Redmond D, Hsu YS, Hadland B, Rafii S. Fli-1 Transcriptionally Integrates Microenvironmental Cues Sensing By Self-Renewing Hematopoietic Stem and Progenitor Cells Blood. 134: 725-725. DOI: 10.1182/Blood-2019-126190  0.545
2019 Hadland B, Varnum-Finney B, Dozono S, Dignum T, Nourigat-Mckay C, Jackson D, Rafii S, Trapnell C, Bernstein ID. Integrated Single Cell Transcriptomics Defines an Engineered Niche Supporting Hematopoietic Stem Cell Development Ex Vivo Blood. 134: 3699-3699. DOI: 10.1182/Blood-2019-126109  0.481
2018 Guo P, Rafii S. Generation of BMEC Lines and BMEC-HSPC Co-culture Assays. Bio-Protocol. 8: e3079. PMID 34532536 DOI: 10.21769/BioProtoc.3079  0.401
2018 Gomez-Salinero JM, Rafii S. Endothelial cell adaptation in regeneration. Science (New York, N.Y.). 362: 1116-1117. PMID 30523098 DOI: 10.1126/Science.Aar4800  0.483
2018 Barcia Durán JG, Lis R, Lu TM, Rafii S. In vitro conversion of adult murine endothelial cells to hematopoietic stem cells. Nature Protocols. PMID 30429596 DOI: 10.1038/Protex.2017.033  0.501
2018 Bhang DH, Kim BJ, Kim BG, Schadler K, Baek KH, Kim YH, Hsiao W, Ding BS, Rafii S, Weiss MJ, Chou ST, Kolon TF, Ginsberg JP, Ryu BY, Ryeom S. Testicular endothelial cells are a critical population in the germline stem cell niche. Nature Communications. 9: 4379. PMID 30348976 DOI: 10.1038/S41467-018-06881-Z  0.494
2018 Rabbany SY, Rafii S. Blood flow forces liver growth. Nature. 562: 42-43. PMID 30275551 DOI: 10.1038/D41586-018-06741-2  0.362
2018 Rafii S, Palikuqi B. Isolation and Characterization of Mouse Organ-Specific Endothelial Transcriptomes. Methods in Molecular Biology (Clifton, N.J.). 1846: 301-308. PMID 30242768 DOI: 10.1007/978-1-4939-8712-2_20  0.484
2018 Merna N, Wong AK, Barahona V, Llanos P, Kunar B, Palikuqi B, Ginsberg M, Rafii S, Rabbany SY. Laminar Shear Stress Modulates Endothelial Luminal Surface Stiffness in a Tissue-Specific Manner. Microcirculation (New York, N.Y. : 1994). e12455. PMID 29665185 DOI: 10.1111/Micc.12455  0.415
2018 Finley LWS, Vardhana SA, Carey BW, Alonso-Curbelo D, Koche R, Chen Y, Wen D, King B, Radler MR, Rafii S, Lowe SW, Allis CD, Thompson CB. Pluripotency transcription factors and Tet1/2 maintain Brd4-independent stem cell identity. Nature Cell Biology. PMID 29662175 DOI: 10.1038/S41556-018-0086-3  0.384
2018 Xu B, Cai L, Butler JM, Chen D, Lu X, Allison DF, Lu R, Rafii S, Parker JS, Zheng D, Wang GG. The Chromatin Remodeler BPTF Activates a Stemness Gene-Expression Program Essential for the Maintenance of Adult Hematopoietic Stem Cells. Stem Cell Reports. PMID 29456179 DOI: 10.1016/J.Stemcr.2018.01.020  0.404
2018 Wertheimer T, Velardi E, Tsai J, Cooper K, Xiao S, Kloss CC, Ottmüller KJ, Mokhtari Z, Brede C, deRoos P, Kinsella S, Palikuqi B, Ginsberg M, Young LF, Kreines F, ... ... Rafii S, et al. Production of BMP4 by endothelial cells is crucial for endogenous thymic regeneration. Science Immunology. 3. PMID 29330161 DOI: 10.1126/Sciimmunol.Aal2736  0.458
2018 Hadland B, Varnum-Finney B, Dozono S, Jackson D, Rafii S, Bernstein ID, Trapnell C. Single Cell Transcriptomics Maps the Embryonic Emergence of HSC and Identifies Intercellular Interactions Regulating HSC Genesis Blood. 132: 5086-5086. DOI: 10.1182/Blood-2018-99-118772  0.471
2018 Durán JGB, Lu TM, Lis R, Rafii S. Reprogrammed Adult Human Endothelium into Hematopoietic Stem Cells Yields Functional T Cells In Vivo Blood. 132: 169-169. DOI: 10.1182/Blood-2018-169  0.411
2018 Hadland B, Varnum-Finney B, Jackson D, Poulos M, Butler J, Rafii S, Bernstein I, Trapnell C. Single Cell Transcriptomics Reconstructs the Embryonic Emergence of HSC and Identifies Ligand-Receptor Interactions Regulating HSC Genesis in the Aorta-Gonad-Mesonephros Vascular Niche Experimental Hematology. 64: S69-S70. DOI: 10.1016/J.Exphem.2018.06.238  0.413
2018 Lis R, Mansilla-Soto J, Duran JGB, Lu T, Sadelain M, Rafii S. Engineering Converted Autologous Hematopoietic Stem Cells From Vascular Endothelial for Treatment of Hemoglobinopathies Experimental Hematology. 64: S46. DOI: 10.1016/J.Exphem.2018.06.055  0.472
2017 Shido K, Chavez D, Cao Z, Ko J, Rafii S, Ding BS. Platelets prime hematopoietic and vascular niche to drive angiocrine-mediated liver regeneration. Signal Transduction and Targeted Therapy. 2. PMID 29201496 DOI: 10.1038/Sigtrans.2016.44  0.37
2017 Itkin T, Gómez-Salinero JM, Rafii S. Open the gates: vascular neurocrine signaling mobilizes hematopoietic stem and progenitor cells. The Journal of Clinical Investigation. PMID 29130939 DOI: 10.1172/Jci98323  0.506
2017 Guo P, Poulos MG, Palikuqi B, Badwe CR, Lis R, Kunar B, Ding BS, Rabbany SY, Shido K, Butler JM, Rafii S. Endothelial jagged-2 sustains hematopoietic stem and progenitor reconstitution after myelosuppression. The Journal of Clinical Investigation. PMID 29058691 DOI: 10.1172/Jci92309  0.55
2017 Kedem A, Aelion-Brauer A, Guo P, Wen D, Ding BS, Lis R, Cheng D, Sandler VM, Rafii S, Rosenwaks Z. Activated ovarian endothelial cells promote early follicular development and survival. Journal of Ovarian Research. 10: 64. PMID 28927438 DOI: 10.1186/S13048-017-0354-Z  0.408
2017 Itkin T, Rafii S. Leukemic Cells "Gas Up" Leaky Bone Marrow Blood Vessels. Cancer Cell. 32: 276-278. PMID 28898691 DOI: 10.1016/J.Ccell.2017.08.012  0.442
2017 Cao Z, Ye T, Sun Y, Ji G, Shido K, Chen Y, Luo L, Na F, Li X, Huang Z, Ko JL, Mittal V, Qiao L, Chen C, Martinez FJ, ... Rafii S, et al. Targeting the vascular and perivascular niches as a regenerative therapy for lung and liver fibrosis. Science Translational Medicine. 9. PMID 28855398 DOI: 10.1126/Scitranslmed.Aai8710  0.429
2017 Benedicto I, Lehmann GL, Ginsberg M, Nolan DJ, Bareja R, Elemento O, Salfati Z, Alam NM, Prusky GT, Llanos P, Rabbany SY, Maminishkis A, Miller SS, Rafii S, Rodriguez-Boulan E. Concerted regulation of retinal pigment epithelium basement membrane and barrier function by angiocrine factors. Nature Communications. 8: 15374. PMID 28524846 DOI: 10.1038/Ncomms15374  0.363
2017 Lis R, Karrasch CC, Poulos MG, Kunar B, Redmond D, Duran JGB, Badwe CR, Schachterle W, Ginsberg M, Xiang J, Tabrizi AR, Shido K, Rosenwaks Z, Elemento O, Speck NA, ... ... Rafii S, et al. Conversion of adult endothelium to immunocompetent haematopoietic stem cells. Nature. PMID 28514438 DOI: 10.1038/Nature22326  0.534
2017 Lee KS, Santagostino SF, Li D, Ramjit A, Serrano K, Ginsberg MD, Ding BS, Rafii S, Madoff DC. Catheter-directed Intraportal Delivery of Endothelial Cell Therapy for Liver Regeneration: A Feasibility Study in a Large-Animal Model of Cirrhosis. Radiology. 162617. PMID 28498793 DOI: 10.1148/Radiol.2017162617  0.413
2017 Hadland BK, Varnum-Finney B, Mandal PK, Rossi DJ, Poulos MG, Butler JM, Rafii S, Yoder MC, Yoshimoto M, Bernstein ID. A Common Origin for B-1a and B-2 Lymphocytes in Clonal Pre- Hematopoietic Stem Cells. Stem Cell Reports. PMID 28479303 DOI: 10.1016/J.Stemcr.2017.04.007  0.368
2017 Huang Y, Rajappa P, Hu W, Hoffman C, Cisse B, Kim JH, Gorge E, Yanowitch R, Cope W, Vartanian E, Xu R, Zhang T, Pisapia D, Xiang J, Huse J, ... ... Rafii S, et al. A proangiogenic signaling axis in myeloid cells promotes malignant progression of glioma. The Journal of Clinical Investigation. PMID 28394259 DOI: 10.1172/Jci86443  0.436
2017 Gori JL, Butler JM, Kunar B, Poulos MG, Ginsberg M, Nolan DJ, Norgaard ZK, Adair JE, Rafii S, Kiem HP. Endothelial Cells Promote Expansion of Long-Term Engrafting Marrow Hematopoietic Stem and Progenitor Cells in Primates. Stem Cells Translational Medicine. 6: 864-876. PMID 28297579 DOI: 10.5966/Sctm.2016-0240  0.511
2017 Guo P, Rafii S. Dangerous Liaisons: Deviant Endothelium NOTCHes toward Tumor Metastasis. Cancer Cell. 31: 301-303. PMID 28292430 DOI: 10.1016/J.Ccell.2017.02.016  0.426
2017 Pasquier J, Gupta R, Rioult D, Hoarau-Véchot J, Courjaret R, Machaca K, Al Suwaidi J, Stanley EG, Rafii S, Elliott DA, Abi Khalil C, Rafii A. Coculturing with endothelial cells promotes in vitro maturation and electrical coupling of human embryonic stem cell-derived cardiomyocytes. The Journal of Heart and Lung Transplantation : the Official Publication of the International Society For Heart Transplantation. PMID 28169114 DOI: 10.1016/J.Healun.2017.01.001  0.48
2017 Schachterle W, Badwe CR, Palikuqi B, Kunar B, Ginsberg M, Lis R, Yokoyama M, Elemento O, Scandura JM, Rafii S. Sox17 drives functional engraftment of endothelium converted from non-vascular cells. Nature Communications. 8: 13963. PMID 28091527 DOI: 10.1038/Ncomms13963  0.508
2017 Wertheimer T, Velardi E, Tsai J, Cooper K, Ottmüller KJ, Mokthari Z, Butler JM, Rafii S, Brink MRMvd, Dudakov JA. Mechanisms Governing Endogenous Thymic Regeneration Blood. 130: 66-66. DOI: 10.1182/Blood.V130.Suppl_1.66.66  0.474
2017 Lyden DC, Rafii S. Webinar | Deciphering cancer: Understanding tumor invasion and the metastatic microenvironment Science. 357: 1168.2-1168. DOI: 10.1126/Science.357.6356.1168-B  0.365
2017 Badwe C, Barcia Duran JG, Kunar B, Lis R, Rafii S. Fli1 is essential for the maintenance of hematopoietic stem cell homeostasis and function Experimental Hematology. 53: S131. DOI: 10.1016/J.Exphem.2017.06.330  0.403
2017 Lis R, Karrasch C, Poulos M, Kunar B, Redmond D, Duran JGB, Badwe C, Ginsberg M, Schachterle W, Xiang J, Tabrizi AR, Shido K, Rosenwaks Z, Elemento O, Speck N, ... ... Rafii S, et al. Conversion of adult endothelium into immune-competent haematopoietic stem cells Experimental Hematology. 53. DOI: 10.1016/J.Exphem.2017.06.183  0.355
2016 Ding BS, Liu CH, Sun Y, Chen Y, Swendeman SL, Jung B, Chavez D, Cao Z, Christoffersen C, Nielsen LB, Schwab SR, Rafii S, Hla T. HDL activation of endothelial sphingosine-1-phosphate receptor-1 (S1P1) promotes regeneration and suppresses fibrosis in the liver. Jci Insight. 1: e87058. PMID 28018969 DOI: 10.1172/Jci.Insight.87058  0.328
2016 Poulos MG, Ramalingam P, Gutkin MC, Kleppe M, Ginsberg M, Crowley MJ, Elemento O, Levine RL, Rafii S, Kitajewski J, Greenblatt MB, Shim JH, Butler JM. Endothelial-specific inhibition of NF-κB enhances functional haematopoiesis. Nature Communications. 7: 13829. PMID 28000664 DOI: 10.1038/Ncomms13829  0.48
2016 Cao Z, Scandura JM, Inghirami GG, Shido K, Ding BS, Rafii S. Molecular Checkpoint Decisions Made by Subverted Vascular Niche Transform Indolent Tumor Cells into Chemoresistant Cancer Stem Cells. Cancer Cell. PMID 27989801 DOI: 10.1016/J.Ccell.2016.11.010  0.439
2016 Gori JL, Butler JM, Kunar B, Poulos MG, Ginsberg M, Nolan DJ, Norgaard ZK, Adair JE, Rafii S, Kiem HP. Endothelial Cells Promote Expansion of Long-Term Engrafting Marrow Hematopoietic Stem and Progenitor Cells in Primates. Stem Cells Translational Medicine. PMID 27742844 DOI: 10.5966/sctm.2016-0240  0.411
2016 Atapattu L, Saha N, Chheang C, Eissman MF, Xu K, Vail ME, Hii L, Llerena C, Liu Z, Horvay K, Abud HE, Kusebauch U, Moritz RL, Ding BS, Cao Z, ... Rafii S, et al. An activated form of ADAM10 is tumor selective and regulates cancer stem-like cells and tumor growth. The Journal of Experimental Medicine. PMID 27503072 DOI: 10.1084/Jem.20151095  0.381
2016 Rafii S, Ginsberg M, Scandura J, Butler JM, Ding BS. Transplantation of Endothelial Cells to Mitigate Acute and Chronic Radiation Injury to Vital Organs. Radiation Research. PMID 27459700 DOI: 10.1667/Rr14461.1  0.447
2016 Liu Y, Giannopoulou EG, Wen D, Falciatori I, Elemento O, Allis CD, Rafii S, Seandel M. Epigenetic profiles signify cell fate plasticity in unipotent spermatogonial stem and progenitor cells. Nature Communications. 7: 11275. PMID 27117588 DOI: 10.1038/Ncomms11275  0.434
2016 Rafii S, Carmeliet P. VEGF-B Improves Metabolic Health through Vascular Pruning of Fat. Cell Metabolism. 23: 571-3. PMID 27076071 DOI: 10.1016/J.Cmet.2016.03.012  0.358
2016 Itkin T, Gur-Cohen S, Spencer JA, Schajnovitz A, Ramasamy SK, Kusumbe AP, Ledergor G, Jung Y, Milo I, Poulos MG, Kalinkovich A, Ludin A, Kollet O, Shakhar G, Butler JM, ... Rafii S, et al. Distinct bone marrow blood vessels differentially regulate haematopoiesis. Nature. PMID 27074509 DOI: 10.1038/Nature17624  0.465
2016 Rafii S, Butler JM, Ding BS. Angiocrine functions of organ-specific endothelial cells. Nature. 529: 316-25. PMID 26791722 DOI: 10.1038/Nature17040  0.457
2016 Cao Z, Lis R, Ginsberg M, Chavez D, Shido K, Rabbany SY, Fong GH, Sakmar TP, Rafii S, Ding BS. Targeting of the pulmonary capillary vascular niche promotes lung alveolar repair and ameliorates fibrosis. Nature Medicine. PMID 26779814 DOI: 10.1038/Nm.4035  0.35
2016 O'Donnell RK, Falcon B, Hanson J, Goldstein WE, Perruzzi C, Rafii S, Aird WC, Benjamin LE. VEGF-A/VEGFR Inhibition Restores Hematopoietic Homeostasis in the Bone Marrow and Attenuates Tumor Growth. Cancer Research. 76: 517-24. PMID 26719538 DOI: 10.1158/0008-5472.Can-14-3023  0.487
2016 Al Thawadi H, Abu-Kaoud N, Al Farsi H, Hoarau-Véchot J, Rafii S, Rafii A, Pasquier J. VE-cadherin cleavage by ovarian cancer microparticles induces β-catenin phosphorylation in endothelial cells. Oncotarget. 7: 5289-305. PMID 26700621 DOI: 10.18632/Oncotarget.6677  0.434
2016 Lis R, Harrasch C, Poulos MG, Duran JG, Schachterle W, Ginsberg M, Rafii A, Shido K, Speck NA, Butler JM, Scandura JM, Rafii S. Direct Conversion of Adult Endothelial Cells into Immunecompetent Long-Term Engraftable Clinically Scalable Hematopoietic Stem Cells: Pathway to Therapeutic Translation Blood. 128: 372-372. DOI: 10.1182/Blood.V128.22.372.372  0.522
2016 Di Giacomo F, Wang X, Fiore D, Consolino L, Phillip J, Gaudiano M, Roman-Gonzalez L, Crescenzo R, Chiaretti S, Gianfelici V, Michael G, Duran JGB, Salinero JMG, Bareja R, Elemento O, ... ... Rafii S, et al. The Pro-Tumorigenic Vascular Niche Sustains the T-Cell Acute Lymphoblastic Leukemia Phenotype and Fosters Resistance to Therapy Blood. 128: 279-279. DOI: 10.1182/Blood.V128.22.279.279  0.425
2016 Lis R, Karrasch C, Poulos M, Barcia Duran JG, Schachterle W, Ginsberg M, Tabrizi AR, Shido K, Speck N, Butler J, Scandura J, Rafii S. Step-wise reprogramming of endothelial cells into immune-competent hematopoietic stem cells Experimental Hematology. 44: S48-S49. DOI: 10.1016/J.Exphem.2016.06.065  0.473
2015 Ginsberg M, Schachterle W, Shido K, Rafii S. Direct conversion of human amniotic cells into endothelial cells without transitioning through a pluripotent state. Nature Protocols. 10: 1975-85. PMID 26540589 DOI: 10.1038/Nprot.2015.126  0.539
2015 Ding BS, Gomi K, Rafii S, Crystal RG, Walters MS. Endothelial MMP14 is required for endothelial dependent growth support of human airway basal cells. Journal of Cell Science. PMID 26116571 DOI: 10.1242/Dev.129791  0.531
2015 Durrans A, Gao D, Gupta R, Fischer KR, Choi H, El Rayes T, Ryu S, Nasar A, Spinelli CF, Andrews W, Elemento O, Nolan D, Stiles B, Rafii S, Narula N, et al. Identification of Reprogrammed Myeloid Cell Transcriptomes in NSCLC. Plos One. 10: e0129123. PMID 26046767 DOI: 10.1371/Journal.Pone.0129123  0.367
2015 Hadland BK, Varnum-Finney B, Poulos MG, Moon RT, Butler JM, Rafii S, Bernstein ID. Endothelium and NOTCH specify and amplify aorta-gonad-mesonephros-derived hematopoietic stem cells. The Journal of Clinical Investigation. 125: 2032-45. PMID 25866967 DOI: 10.1172/Jci80137  0.523
2015 Choi H, Sheng J, Gao D, Li F, Durrans A, Ryu S, Lee SB, Narula N, Rafii S, Elemento O, Altorki NK, Wong ST, Mittal V. Transcriptome analysis of individual stromal cell populations identifies stroma-tumor crosstalk in mouse lung cancer model. Cell Reports. 10: 1187-201. PMID 25704820 DOI: 10.1016/J.Celrep.2015.01.040  0.381
2015 Gori JL, Butler JM, Chan YY, Chandrasekaran D, Poulos MG, Ginsberg M, Nolan DJ, Elemento O, Wood BL, Adair JE, Rafii S, Kiem HP. Vascular niche promotes hematopoietic multipotent progenitor formation from pluripotent stem cells. The Journal of Clinical Investigation. 125: 1243-54. PMID 25664855 DOI: 10.1172/Jci79328  0.539
2015 Ghiabi P, Jiang J, Pasquier J, Maleki M, Abu-Kaoud N, Halabi N, Guerrouahen BS, Rafii S, Rafii A. Breast cancer cells promote a notch-dependent mesenchymal phenotype in endothelial cells participating to a pro-tumoral niche. Journal of Translational Medicine. 13: 27. PMID 25623554 DOI: 10.1186/S12967-015-0386-3  0.475
2015 Rafii S, Cao Z, Lis R, Siempos II, Chavez D, Shido K, Rabbany SY, Ding BS. Platelet-derived SDF-1 primes the pulmonary capillary vascular niche to drive lung alveolar regeneration. Nature Cell Biology. 17: 123-36. PMID 25621952 DOI: 10.1038/Ncb3096  0.349
2015 Kao DI, Lacko LA, Ding BS, Huang C, Phung K, Gu G, Rafii S, Stuhlmann H, Chen S. Endothelial cells control pancreatic cell fate at defined stages through EGFL7 signaling. Stem Cell Reports. 4: 181-9. PMID 25601205 DOI: 10.1016/J.Stemcr.2014.12.008  0.523
2015 Gürsel DB, Banu MA, Berry N, Marongiu R, Burkhardt JK, Kobylarz K, Kaplitt MG, Rafii S, Boockvar JA. Tight regulation between cell survival and programmed cell death in GBM stem-like cells by EGFR/GSK3b/PP2A signaling. Journal of Neuro-Oncology. 121: 19-29. PMID 25344882 DOI: 10.1007/S11060-014-1602-3  0.435
2015 Rafii S, Butler JM, Michael G, Gori JL, Kiem H, Jospeh S. Vascular Niche-Derived Angiocrine Factors Specify and Maintain Hematopoietic Stem Cells Blood. 126: SCI-25-SCI-25. DOI: 10.1182/Blood.V126.23.Sci-25.Sci-25  0.559
2015 Itkin T, Gur Cohen S, Spencer JA, Schajnovitz A, Ramasamy SK, Kusumbe AP, Jung Y, Ledergor G, Milo I, Poulos MG, Fernandez MG, Kalinkovich A, Ludin A, Kollet O, Shakhar G, ... ... Rafii S, et al. Distinct Bone Marrow Blood Vessels Differentially Regulate Normal and Malignant Hematopoietic Stem and Progenitor Cells Blood. 126: 664-664. DOI: 10.1182/Blood.V126.23.664.664  0.529
2015 Rafii S. Executive functions of the cascular niche in hematopoietic specification maintenance and regeneration Experimental Hematology. 43: S35. DOI: 10.1016/J.Exphem.2015.06.031  0.303
2015 Boroda N, Wong AK, Llanos P, Rafii S, Rabbany SY. Characterization of Biomechanical Properties of Primary Endothelial Cells Exposed to Shear Stress Biophysical Journal. 108: 563a. DOI: 10.1016/J.Bpj.2014.11.3086  0.339
2015 Rayes TE, Catena R, Rafii S, Altorki N, Mittal V. Inflammation and Lung Cancer: The Link to Angiogenesis Springer: New York. 137-159. DOI: 10.1007/978-1-4939-2724-1_5  0.312
2014 Ghiabi P, Jiang J, Pasquier J, Maleki M, Abu-Kaoud N, Rafii S, Rafii A. Endothelial cells provide a notch-dependent pro-tumoral niche for enhancing breast cancer survival, stemness and pro-metastatic properties. Plos One. 9: e112424. PMID 25380486 DOI: 10.1371/Journal.Pone.0112424  0.461
2014 Guerrouahen BS, Pasquier J, Kaoud NA, Maleki M, Beauchamp MC, Yasmeen A, Ghiabi P, Lis R, Vidal F, Saleh A, Gotlieb WH, Rafii S, Rafii A. Akt-activated endothelium constitutes the niche for residual disease and resistance to bevacizumab in ovarian cancer. Molecular Cancer Therapeutics. 13: 3123-36. PMID 25319392 DOI: 10.1158/1535-7163.Mct-13-1053  0.416
2014 Prasain N, Lee MR, Vemula S, Meador JL, Yoshimoto M, Ferkowicz MJ, Fett A, Gupta M, Rapp BM, Saadatzadeh MR, Ginsberg M, Elemento O, Lee Y, Voytik-Harbin SL, Chung HM, ... ... Rafii S, et al. Differentiation of human pluripotent stem cells to cells similar to cord-blood endothelial colony-forming cells. Nature Biotechnology. 32: 1151-7. PMID 25306246 DOI: 10.1038/Nbt.3048  0.537
2014 Wu T, Liu Y, Wen D, Tseng Z, Tahmasian M, Zhong M, Rafii S, Stadtfeld M, Hochedlinger K, Xiao A. Histone variant H2A.X deposition pattern serves as a functional epigenetic mark for distinguishing the developmental potentials of iPSCs. Cell Stem Cell. 15: 281-94. PMID 25192463 DOI: 10.1016/J.Stem.2014.06.004  0.339
2014 Poulos MG, Gars EJ, Gutkin MC, Kloss CC, Ginsberg M, Scandura JM, Rafii S, Butler JM. Activation of the vascular niche supports leukemic progression and resistance to chemotherapy. Experimental Hematology. 42: 976-86.e1-3. PMID 25179751 DOI: 10.1016/J.Exphem.2014.08.003  0.51
2014 Sandler VM, Lis R, Liu Y, Kedem A, James D, Elemento O, Butler JM, Scandura JM, Rafii S. Reprogramming human endothelial cells to haematopoietic cells requires vascular induction. Nature. 511: 312-8. PMID 25030167 DOI: 10.1038/Nature13547  0.553
2014 Sachs C, Robinson BD, Andres Martin L, Webster T, Gilbert M, Lo HY, Rafii S, Ng CK, Seandel M. Evaluation of candidate spermatogonial markers ID4 and GPR125 in testes of adult human cadaveric organ donors. Andrology. 2: 607-14. PMID 24902969 DOI: 10.1111/J.2047-2927.2014.00226.X  0.354
2014 Wen D, Saiz N, Rosenwaks Z, Hadjantonakis AK, Rafii S. Completely ES cell-derived mice produced by tetraploid complementation using inner cell mass (ICM) deficient blastocysts. Plos One. 9: e94730. PMID 24733255 DOI: 10.1371/Journal.Pone.0094730  0.379
2014 Walter RB, Laszlo GS, Lionberger JM, Pollard JA, Harrington KH, Gudgeon CJ, Othus M, Rafii S, Meshinchi S, Appelbaum FR, Bernstein ID. Heterogeneity of clonal expansion and maturation-linked mutation acquisition in hematopoietic progenitors in human acute myeloid leukemia. Leukemia. 28: 1969-77. PMID 24721792 DOI: 10.1038/Leu.2014.107  0.378
2014 Cao Z, Ding BS, Guo P, Lee SB, Butler JM, Casey SC, Simons M, Tam W, Felsher DW, Shido K, Rafii A, Scandura JM, Rafii S. Angiocrine factors deployed by tumor vascular niche induce B cell lymphoma invasiveness and chemoresistance. Cancer Cell. 25: 350-65. PMID 24651014 DOI: 10.1016/J.Ccr.2014.02.005  0.494
2014 James D, Rafii S. Maladapted endothelial cells flip the mesenchymal switch. Science Translational Medicine. 6: 227fs12. PMID 24622512 DOI: 10.1126/Scitranslmed.3008623  0.435
2014 Anastasia A, Deinhardt K, Wang S, Martin L, Nichol D, Irmady K, Trinh J, Parada L, Rafii S, Hempstead BL, Kermani P. Trkb signaling in pericytes is required for cardiac microvessel stabilization. Plos One. 9: e87406. PMID 24498100 DOI: 10.1371/Journal.Pone.0087406  0.457
2014 Pasquier J, Thawadi HA, Ghiabi P, Abu-Kaoud N, Maleki M, Guerrouahen BS, Vidal F, Courderc B, Ferron G, Martinez A, Al Sulaiti H, Gupta R, Rafii S, Rafii A. Microparticles mediated cross-talk between tumoral and endothelial cells promote the constitution of a pro-metastatic vascular niche through Arf6 up regulation. Cancer Microenvironment : Official Journal of the International Cancer Microenvironment Society. 7: 41-59. PMID 24424657 DOI: 10.1007/S12307-013-0142-2  0.51
2014 Ding BS, Cao Z, Lis R, Nolan DJ, Guo P, Simons M, Penfold ME, Shido K, Rabbany SY, Rafii S. Divergent angiocrine signals from vascular niche balance liver regeneration and fibrosis. Nature. 505: 97-102. PMID 24256728 DOI: 10.1038/Nature12681  0.435
2014 Yamamoto M, Rafii S, Rabbany SY. Scaffold biomaterials for nano-pathophysiology. Advanced Drug Delivery Reviews. 74: 104-14. PMID 24075835 DOI: 10.1016/J.Addr.2013.09.009  0.37
2014 Israely E, Ginsberg M, Nolan D, Ding BS, James D, Elemento O, Rafii S, Rabbany SY. Akt suppression of TGFβ signaling contributes to the maintenance of vascular identity in embryonic stem cell-derived endothelial cells. Stem Cells (Dayton, Ohio). 32: 177-90. PMID 23963623 DOI: 10.1002/Stem.1521  0.835
2014 Hadland BK, Varnum-Finney B, Moon RT, Poulos MG, Butler JM, Rafii S, Bernstein ID. Notch Signaling By Either Notch1 or Notch2 Mediates Expansion of AGM-Derived Long-Term HSC Populations in Vitro Blood. 124: 2897-2897. DOI: 10.1182/Blood.V124.21.2897.2897  0.445
2014 Wertheimer T, Kloss CC, Velardi E, Brede C, Ginsberg M, Kreines FM, Zakrzewski JL, Tuckett AZ, Tsai JJ, Smith OM, Levy ER, Beilhack A, Rafii S, Butler JM, van den Brink MR, et al. Endothelial Cells Promote Endogenous Thymic Regeneration after Injury Via BMP4 Signaling Blood. 124: 2429-2429. DOI: 10.1182/Blood.V124.21.2429.2429  0.477
2014 Guerrouahen BS, Pasquier J, Kaoud NA, Beauchamp M, Maleki M, Ghiabi P, Lis R, Saleh A, Gotlieb WH, Rafii S, Rafii A. Abstract 2998: Akt-activated endothelium constitute the niche for residual disease and resistance to bevacizumab in ovarian cancer Cancer Research. 74: 2998-2998. DOI: 10.1158/1538-7445.Am2014-2998  0.392
2013 Walters MS, Gomi K, Ashbridge B, Moore MA, Arbelaez V, Heldrich J, Ding BS, Rafii S, Staudt MR, Crystal RG. Generation of a human airway epithelium derived basal cell line with multipotent differentiation capacity. Respiratory Research. 14: 135. PMID 24298994 DOI: 10.1186/1465-9921-14-135  0.34
2013 Chavala SH, Kim Y, Tudisco L, Cicatiello V, Milde T, Kerur N, Claros N, Yanni S, Guaiquil VH, Hauswirth WW, Penn JS, Rafii S, De Falco S, Lee TC, Ambati J. Retinal angiogenesis suppression through small molecule activation of p53. The Journal of Clinical Investigation. 123: 4170-81. PMID 24018558 DOI: 10.1172/Jci67315  0.382
2013 Poulos MG, Guo P, Kofler NM, Pinho S, Gutkin MC, Tikhonova A, Aifantis I, Frenette PS, Kitajewski J, Rafii S, Butler JM. Endothelial Jagged-1 is necessary for homeostatic and regenerative hematopoiesis. Cell Reports. 4: 1022-34. PMID 24012753 DOI: 10.1016/J.Celrep.2013.07.048  0.51
2013 Raynaud CM, Butler JM, Halabi NM, Ahmad FS, Ahmed B, Rafii S, Rafii A. Endothelial cells provide a niche for placental hematopoietic stem/progenitor cell expansion through broad transcriptomic modification. Stem Cell Research. 11: 1074-90. PMID 23978474 DOI: 10.1016/J.Scr.2013.07.010  0.504
2013 Nolan DJ, Ginsberg M, Israely E, Palikuqi B, Poulos MG, James D, Ding BS, Schachterle W, Liu Y, Rosenwaks Z, Butler JM, Xiang J, Rafii A, Shido K, Rabbany SY, ... ... Rafii S, et al. Molecular signatures of tissue-specific microvascular endothelial cell heterogeneity in organ maintenance and regeneration. Developmental Cell. 26: 204-19. PMID 23871589 DOI: 10.1016/J.Devcel.2013.06.017  0.806
2013 Pasquier J, Guerrouahen BS, Al Thawadi H, Ghiabi P, Maleki M, Abu-Kaoud N, Jacob A, Mirshahi M, Galas L, Rafii S, Le Foll F, Rafii A. Preferential transfer of mitochondria from endothelial to cancer cells through tunneling nanotubes modulates chemoresistance. Journal of Translational Medicine. 11: 94. PMID 23574623 DOI: 10.1186/1479-5876-11-94  0.461
2013 Westerweel PE, Teraa M, Rafii S, Jaspers JE, White IA, Hooper AT, Doevendans PA, Verhaar MC. Impaired endothelial progenitor cell mobilization and dysfunctional bone marrow stroma in diabetes mellitus. Plos One. 8: e60357. PMID 23555959 DOI: 10.1371/Journal.Pone.0060357  0.676
2013 Butler JM, Rafii S. Stem cells: Painkillers caught in blood-cell trafficking. Nature. 495: 317-8. PMID 23485972 DOI: 10.1038/Nature12085  0.484
2013 Lis R, Rafii S, James D. Wading through the waves of human embryonic hemogenesis. Cell Cycle (Georgetown, Tex.). 12: 859-60. PMID 23442793 DOI: 10.4161/Cc.24081  0.516
2013 Brenet F, Kermani P, Spektor R, Rafii S, Scandura JM. TGFβ restores hematopoietic homeostasis after myelosuppressive chemotherapy. The Journal of Experimental Medicine. 210: 623-39. PMID 23440043 DOI: 10.1084/Jem.20121610  0.424
2013 Jain S, Cohen J, Ward MM, Kornhauser N, Chuang E, Cigler T, Moore A, Donovan D, Lam C, Cobham MV, Schneider S, Hurtado Rúa SM, Benkert S, Mathijsen Greenwood C, Zelkowitz R, ... ... Rafii S, et al. Tetrathiomolybdate-associated copper depletion decreases circulating endothelial progenitor cells in women with breast cancer at high risk of relapse. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. 24: 1491-8. PMID 23406736 DOI: 10.1093/Annonc/Mds654  0.319
2013 Rafii S, Kloss CC, Butler JM, Ginsberg M, Gars E, Lis R, Zhan Q, Josipovic P, Ding BS, Xiang J, Elemento O, Zaninovic N, Rosenwaks Z, Sadelain M, Rafii JA, et al. Human ESC-derived hemogenic endothelial cells undergo distinct waves of endothelial to hematopoietic transition. Blood. 121: 770-80. PMID 23169780 DOI: 10.1182/Blood-2012-07-444208  0.533
2013 Gori JL, Butler JM, Chandrasekaran D, Beard BC, Nolan DJ, Ginsberg M, Adair JE, Rafii S, Kiem H. In Vivo Selection and Long-Term Engraftment Of Hematopoietic Stem Cells Generated Via Vascular Niche Induction Of Nonhuman Primate Induced Pluripotent Stem Cells Blood. 122: 466-466. DOI: 10.1182/Blood.V122.21.466.466  0.431
2013 Hadland BK, Varnum-Finney B, Moon RT, Butler JM, Rafii S, Bernstein ID. AGM-Derived Endothelial Cells and Notch Ligands Provide Embryonic Hematopoietic Stem Cell-Supportive Niches In Vitro Blood. 122: 1167-1167. DOI: 10.1182/Blood.V122.21.1167.1167  0.487
2013 Guerrouahen BS, Pasquier J, Kaoud NA, Beauchamp M, Ghiabi P, Maleki M, Lis R, Saleh A, Gotlieb WH, Rafii S, Rafii A. Abstract B70: Akt-activated endothelium constitute a niche for residual disease and resistance to bevacizumab in ovarian cancer Clinical Cancer Research. 19. DOI: 10.1158/1078-0432.Ovca13-B70  0.414
2013 Kedem A, Aelion Brauer A, Wen D, Liu H, Rafii S, Rosenwaks Z. Endothelial-derived angiocrine signals promote growth and survival of early follicles: an ex-vivo model Fertility and Sterility. 100: S344. DOI: 10.1016/J.Fertnstert.2013.07.865  0.395
2013 Aelion Brauer A, Kedem A, Lis R, Guo P, Rafii S, Rosenwaks Z. Isolation and characterization of ovarian endothelial cells (ECs): a novel tool in understanding the role of ovarian endothelial cells in reproductive biology Fertility and Sterility. 100: S60-S61. DOI: 10.1016/J.Fertnstert.2013.07.1868  0.471
2012 Ginsberg M, James D, Ding BS, Nolan D, Geng F, Butler JM, Schachterle W, Pulijaal VR, Mathew S, Chasen ST, Xiang J, Rosenwaks Z, Shido K, Elemento O, Rabbany SY, ... Rafii S, et al. Efficient direct reprogramming of mature amniotic cells into endothelial cells by ETS factors and TGFβ suppression. Cell. 151: 559-75. PMID 23084400 DOI: 10.1016/J.Cell.2012.09.032  0.543
2012 Gars E, Rafii S. It takes 2 to thrombopoies in the vascular niche. Blood. 120: 2775-6. PMID 23043022 DOI: 10.1182/Blood-2012-07-435172  0.451
2012 Jung B, Obinata H, Galvani S, Mendelson K, Ding BS, Skoura A, Kinzel B, Brinkmann V, Rafii S, Evans T, Hla T. Flow-regulated endothelial S1P receptor-1 signaling sustains vascular development. Developmental Cell. 23: 600-10. PMID 22975328 DOI: 10.1016/J.Devcel.2012.07.015  0.394
2012 Butler JM, Rafii S. Generation of a vascular niche for studying stem cell homeostasis. Methods in Molecular Biology (Clifton, N.J.). 904: 221-33. PMID 22890935 DOI: 10.1007/978-1-61779-943-3_18  0.522
2012 Butler JM, Gars EJ, James DJ, Nolan DJ, Scandura JM, Rafii S. Development of a vascular niche platform for expansion of repopulating human cord blood stem and progenitor cells. Blood. 120: 1344-7. PMID 22709690 DOI: 10.1182/Blood-2011-12-398115  0.471
2012 Curradi G, Walters MS, Ding BS, Rafii S, Hackett NR, Crystal RG. Airway basal cell vascular endothelial growth factor-mediated cross-talk regulates endothelial cell-dependent growth support of human airway basal cells. Cellular and Molecular Life Sciences : Cmls. 69: 2217-31. PMID 22382924 DOI: 10.1007/S00018-012-0922-8  0.523
2012 Gao D, Joshi N, Choi H, Ryu S, Hahn M, Catena R, Sadik H, Argani P, Wagner P, Vahdat LT, Port JL, Stiles B, Sukumar S, Altorki NK, Rafii S, et al. Myeloid progenitor cells in the premetastatic lung promote metastases by inducing mesenchymal to epithelial transition. Cancer Research. 72: 1384-94. PMID 22282653 DOI: 10.1158/0008-5472.Can-11-2905  0.384
2012 Jain S, Ward MM, O'Loughlin J, Boeck M, Wiener N, Chuang E, Cigler T, Moore A, Donovan D, Lam C, Cobham MV, Schneider S, Christos P, Baergen RN, Swistel A, ... ... Rafii S, et al. Incremental increase in VEGFR1⁺ hematopoietic progenitor cells and VEGFR2⁺ endothelial progenitor cells predicts relapse and lack of tumor response in breast cancer patients. Breast Cancer Research and Treatment. 132: 235-42. PMID 22160642 DOI: 10.1007/S10549-011-1906-3  0.399
2012 Brenet FA, Kermani P, Rafii S, Scandura JM. TGFβ Restores Hematopoietic Homeostasis After Chemotherapy. Blood. 120: 2344-2344. DOI: 10.1182/Blood.V120.21.2344.2344  0.442
2012 Jain S, Rua SH, Cohen J, Ward MM, Boeck M, Wiener N, Chuang E, Cigler T, Moore A, Donovan D, Lam C, Cobham M, Schneider S, Baergen R, Lane ME, ... ... Rafii S, et al. Abstract 2699: Phase II study evaluating the effect of tetrathiomolybdate on circulating endothelial progenitor cells in patients with high risk for breast cancer recurrence Cancer Research. 72: 2699-2699. DOI: 10.1158/1538-7445.Am2012-2699  0.357
2012 Singer T, Ding B-, Wen D, Kedem A, Rafii S, Rosenwaks Z. Can High Dose Aspirin Reduce Vascular Permeability in Ovarian Hyperstimulation Syndrome (OHSS) – A Mouse Model Journal of Minimally Invasive Gynecology. 19. DOI: 10.1016/J.Jmig.2012.08.047  0.315
2011 Jain S, Cohen JA, Ward MM, O'Loughlin J, Boeck M, Wiener N, Chuang E, Cigler T, Moore A, Donovan D, Lam C, Cobham ME, Schneider SE, Christos PJ, Lane ME, ... ... Rafii S, et al. The effect of tetrathiomolybdate on endothelial progenitor cells in patients at high risk for breast cancer recurrence. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 1054. PMID 28020656 DOI: 10.1200/Jco.2011.29.15_Suppl.1054  0.408
2011 Kimura Y, Ding B, Imai N, Nolan DJ, Butler JM, Rafii S. C-kit-mediated functional positioning of stem cells to their niches is essential for maintenance and regeneration of adult hematopoiesis Plos One. 6. PMID 22046410 DOI: 10.1371/Journal.Pone.0026918  0.415
2011 Ding BS, Nolan DJ, Guo P, Babazadeh AO, Cao Z, Rosenwaks Z, Crystal RG, Simons M, Sato TN, Worgall S, Shido K, Rabbany SY, Rafii S. Endothelial-derived angiocrine signals induce and sustain regenerative lung alveolarization. Cell. 147: 539-53. PMID 22036563 DOI: 10.1016/J.Cell.2011.10.003  0.435
2011 Hodges E, Molaro A, Dos Santos CO, Thekkat P, Song Q, Uren PJ, Park J, Butler J, Rafii S, McCombie WR, Smith AD, Hannon GJ. Directional DNA methylation changes and complex intermediate states accompany lineage specificity in the adult hematopoietic compartment. Molecular Cell. 44: 17-28. PMID 21924933 DOI: 10.1016/J.Molcel.2011.08.026  0.358
2011 Schmidt T, Kharabi Masouleh B, Loges S, Cauwenberghs S, Fraisl P, Maes C, Jonckx B, De Keersmaecker K, Kleppe M, Tjwa M, Schenk T, Vinckier S, Fragoso R, De Mol M, Beel K, ... ... Rafii S, et al. Loss or inhibition of stromal-derived PlGF prolongs survival of mice with imatinib-resistant Bcr-Abl1(+) leukemia. Cancer Cell. 19: 740-53. PMID 21665148 DOI: 10.1016/J.Ccr.2011.05.007  0.394
2011 James D, Zhan Q, Kloss C, Zaninovic N, Rosenwaks Z, Rafii S. Lentiviral transduction and clonal selection of hESCs with endothelial-specific transgenic reporters. Current Protocols in Stem Cell Biology. Unit1F.12. PMID 21509935 DOI: 10.1002/9780470151808.Sc01F12S17  0.507
2011 Maretzky T, Evers A, Zhou W, Swendeman SL, Wong PM, Rafii S, Reiss K, Blobel CP. Migration of growth factor-stimulated epithelial and endothelial cells depends on EGFR transactivation by ADAM17. Nature Communications. 2: 229. PMID 21407195 DOI: 10.1038/Ncomms1232  0.445
2011 Hormigo A, Ding BS, Rafii S. A target for antiangiogenic therapy: vascular endothelium derived from glioblastoma. Proceedings of the National Academy of Sciences of the United States of America. 108: 4271-2. PMID 21383166 DOI: 10.1073/Pnas.1019656108  0.509
2011 Jain S, Ward MM, O'Loughlin J, Boeck MA, Wiener N, Chuang E, Cigler T, Moore A, Donovan D, Lam C, Cobham MV, Schneider SE, Christos P, Baergen RN, Lane ME, ... ... Rafii S, et al. Abstract 4720: Incremental increase in VEGFR1+ and VEGFR2+ hemangiogenic progenitor cells predict relapse and tumor response in breast cancer (BC) patients Cancer Research. 71: 4720-4720. DOI: 10.1158/1538-7445.Am2011-4720  0.386
2010 Ding BS, Nolan DJ, Butler JM, James D, Babazadeh AO, Rosenwaks Z, Mittal V, Kobayashi H, Shido K, Lyden D, Sato TN, Rabbany SY, Rafii S. Inductive angiocrine signals from sinusoidal endothelium are required for liver regeneration. Nature. 468: 310-5. PMID 21068842 DOI: 10.1038/Nature09493  0.488
2010 Kobayashi H, Butler JM, O'Donnell R, Kobayashi M, Ding BS, Bonner B, Chiu VK, Nolan DJ, Shido K, Benjamin L, Rafii S. Angiocrine factors from Akt-activated endothelial cells balance self-renewal and differentiation of haematopoietic stem cells. Nature Cell Biology. 12: 1046-56. PMID 20972423 DOI: 10.1038/Ncb2108  0.56
2010 García-Fernández M, Kissel H, Brown S, Gorenc T, Schile AJ, Rafii S, Larisch S, Steller H. Sept4/ARTS is required for stem cell apoptosis and tumor suppression. Genes & Development. 24: 2282-93. PMID 20952537 DOI: 10.1101/Gad.1970110  0.409
2010 Hobbs RM, Seandel M, Falciatori I, Rafii S, Pandolfi PP. Plzf regulates germline progenitor self-renewal by opposing mTORC1. Cell. 142: 468-79. PMID 20691905 DOI: 10.1016/J.Cell.2010.06.041  0.419
2010 Agarwal U, Ghalayini W, Dong F, Weber K, Zou YR, Rabbany SY, Rafii S, Penn MS. Role of cardiac myocyte CXCR4 expression in development and left ventricular remodeling after acute myocardial infarction. Circulation Research. 107: 667-76. PMID 20634485 DOI: 10.1161/Circresaha.110.223289  0.3
2010 Rafii S, Nolan D. Cholesterol activates vascular niche and hematopoiesis. Blood. 115: 3857-8. PMID 20466867 DOI: 10.1182/Blood-2010-02-261388  0.526
2010 Rabbany SY, James D, Rafii S. New dimensions in vascular engineering: opportunities for cancer biology. Tissue Engineering. Part A. 16: 2157-9. PMID 20367255 DOI: 10.1089/Ten.Tea.2010.0183  0.357
2010 Butler JM, Nolan DJ, Vertes EL, Varnum-Finney B, Kobayashi H, Hooper AT, Seandel M, Shido K, White IA, Kobayashi M, Witte L, May C, Shawber C, Kimura Y, Kitajewski J, ... ... Rafii S, et al. Endothelial cells are essential for the self-renewal and repopulation of Notch-dependent hematopoietic stem cells. Cell Stem Cell. 6: 251-64. PMID 20207228 DOI: 10.1016/J.Stem.2010.02.001  0.753
2010 Butler JM, Kobayashi H, Rafii S. Instructive role of the vascular niche in promoting tumour growth and tissue repair by angiocrine factors. Nature Reviews. Cancer. 10: 138-46. PMID 20094048 DOI: 10.1038/Nrc2791  0.479
2010 James D, Nam HS, Seandel M, Nolan D, Janovitz T, Tomishima M, Studer L, Lee G, Lyden D, Benezra R, Zaninovic N, Rosenwaks Z, Rabbany SY, Rafii S. Expansion and maintenance of human embryonic stem cell-derived endothelial cells by TGFbeta inhibition is Id1 dependent. Nature Biotechnology. 28: 161-6. PMID 20081865 DOI: 10.1038/Nbt.1605  0.555
2010 Yamamoto M, James D, Li H, Butler J, Rafii S, Rabbany S. Generation of stable co-cultures of vascular cells in a honeycomb alginate scaffold. Tissue Engineering. Part A. 16: 299-308. PMID 19705957 DOI: 10.1089/Ten.Tea.2009.0010  0.461
2010 Rafii S, Butler JM. Hematopoietic Support by Endothelium Blood. 116: SCI-45-SCI-45. DOI: 10.1182/Blood.V116.21.Sci-45.Sci-45  0.571
2010 Liang J, Tilki D, Kobayashi H, Rafii S, Seandel M. Abstract 1298: Mechanisms of endothelial trophic support of genitourinary tumors Cancer Research. 70: 1298-1298. DOI: 10.1158/1538-7445.Am10-1298  0.498
2010 Jain S, Ward M, O'Laughlin J, Chuang E, Cigler T, Moore A, Donovan D, Schneider S, Cobham M, Wiener N, Lam C, Christos P, Lane M, Rafii S, Vahdat L. Abstract P2-16-14: The Effect of Tetrathiomolybdate (TM) on Circulating Endothelial Progenitor Cells in Women at Moderate to High Risk of BC Recurrence Cancer Research. 70. DOI: 10.1158/0008-5472.Sabcs10-P2-16-14  0.321
2009 Chan AS, Jensen KK, Skokos D, Doty S, Lederman HK, Kaplan RN, Rafii S, Rivella S, Lyden D. Id1 represses osteoclast-dependent transcription and affects bone formation and hematopoiesis. Plos One. 4: e7955. PMID 19956687 DOI: 10.1371/Journal.Pone.0007955  0.343
2009 Tilki D, Hohn HP, Ergün B, Rafii S, Ergün S. Emerging biology of vascular wall progenitor cells in health and disease. Trends in Molecular Medicine. 15: 501-9. PMID 19828379 DOI: 10.1016/J.Molmed.2009.09.004  0.512
2009 Kopp HG, Hooper AT, Avecilla ST, Rafii S. Functional heterogeneity of the bone marrow vascular niche. Annals of the New York Academy of Sciences. 1176: 47-54. PMID 19796232 DOI: 10.1111/J.1749-6632.2009.04964.X  0.821
2009 Chen L, Zhang JJ, Rafii S, Huang XY. Suppression of tumor angiogenesis by Galpha(13) haploinsufficiency. The Journal of Biological Chemistry. 284: 27409-15. PMID 19654325 DOI: 10.1074/Jbc.M109.025460  0.371
2009 Hooper AT, Shmelkov SV, Gupta S, Milde T, Bambino K, Gillen K, Goetz M, Chavala S, Baljevic M, Murphy AJ, Valenzuela DM, Gale NW, Thurston G, Yancopoulos GD, Vahdat L, ... ... Rafii S, et al. Angiomodulin is a specific marker of vasculature and regulates vascular endothelial growth factor-A-dependent neoangiogenesis. Circulation Research. 105: 201-8. PMID 19542015 DOI: 10.1161/Circresaha.109.196790  0.722
2009 Zhang F, Tsai S, Kato K, Yamanouchi D, Wang C, Rafii S, Liu B, Kent KC. Transforming growth factor-beta promotes recruitment of bone marrow cells and bone marrow-derived mesenchymal stem cells through stimulation of MCP-1 production in vascular smooth muscle cells. The Journal of Biological Chemistry. 284: 17564-74. PMID 19406748 DOI: 10.1074/Jbc.M109.013987  0.416
2009 Greenfield JP, Jin DK, Young LM, Christos PJ, Abrey L, Rafii S, Gutin PH. Surrogate markers predict angiogenic potential and survival in patients with glioblastoma multiforme. Neurosurgery. 64: 819-26; discussion 8. PMID 19404145 DOI: 10.1227/01.Neu.0000343742.06625.Db  0.446
2009 Gyan B, Goka BQ, Adjei GO, Tetteh JKA, Kusi KA, Aikins A, Dodoo D, Lesser ML, Sison CP, Das S, Howard ME, Milbank E, Fischer K, Rafii S, Jin D, et al. Cerebral malaria is associated with low levels of circulating endothelial progenitor cells in african children American Journal of Tropical Medicine and Hygiene. 80: 541-546. PMID 19346372 DOI: 10.4269/Ajtmh.2009.80.541  0.39
2009 Hooper AT, Butler JM, Nolan DJ, Kranz A, Iida K, Kobayashi M, Kopp HG, Shido K, Petit I, Yanger K, James D, Witte L, Zhu Z, Wu Y, Pytowski B, ... ... Rafii S, et al. Engraftment and reconstitution of hematopoiesis is dependent on VEGFR2-mediated regeneration of sinusoidal endothelial cells. Cell Stem Cell. 4: 263-74. PMID 19265665 DOI: 10.1016/J.Stem.2009.01.006  0.747
2009 Passegué E, Rafii S, Herlyn M. Cancer stem cells are everywhere. Nature Medicine. 15: 23. PMID 19129778 DOI: 10.1038/Nm0109-23  0.365
2009 Tsai S, Butler J, Rafii S, Liu B, Kent KC. The role of progenitor cells in the development of intimal hyperplasia. Journal of Vascular Surgery. 49: 502-10. PMID 18945574 DOI: 10.1016/J.Jvs.2008.07.060  0.445
2009 Kobayashi H, Butler J, Vertes E, Zhang L, Kobayashi M, Rafii S. Activation State of the Vascular Niche Regulates Homeostasis of the Normal and Malignant Hematopoietic Stem Cells. Blood. 114: 3624-3624. DOI: 10.1182/Blood.V114.22.3624.3624  0.533
2009 Vahdat L, Ward M, Chuang E, Cigler T, Moore A, Donovan D, Cobham M, Schpero J, Wiener N, Blinder V, Christos P, Rafii S, Lane M. A Phase II Trial Tetrathiomolybdate (TM), a Copper Depleting Compound, and Its Effect on Circulating Endothelial Progenitor Cells (EPCs) in Patients with Breast Cancer (BC) at High Risk of Recurrence. Cancer Research. 69: 6090-6090. DOI: 10.1158/0008-5472.Sabcs-09-6090  0.31
2008 Ruan J, Hajjar K, Rafii S, Leonard JP. Angiogenesis and antiangiogenic therapy in non-Hodgkin's lymphoma. Annals of Oncology : Official Journal of the European Society For Medical Oncology. 20: 413-24. PMID 19088170 DOI: 10.1093/Annonc/Mdn666  0.518
2008 Seandel M, Butler JM, Kobayashi H, Hooper AT, White IA, Zhang F, Vertes EL, Kobayashi M, Zhang Y, Shmelkov SV, Hackett NR, Rabbany S, Boyer JL, Rafii S. Generation of a functional and durable vascular niche by the adenoviral E4ORF1 gene. Proceedings of the National Academy of Sciences of the United States of America. 105: 19288-93. PMID 19036927 DOI: 10.1073/Pnas.0805980105  0.753
2008 Peinado H, Rafii S, Lyden D. Inflammation joins the "niche". Cancer Cell. 14: 347-9. PMID 18977322 DOI: 10.1016/J.Ccr.2008.10.012  0.392
2008 Westerweel PE, Visseren FL, Hajer GR, Olijhoek JK, Hoefer IE, de Bree P, Rafii S, Doevendans PA, Verhaar MC. Endothelial progenitor cell levels in obese men with the metabolic syndrome and the effect of simvastatin monotherapy vs. simvastatin/ezetimibe combination therapy. European Heart Journal. 29: 2808-17. PMID 18824462 DOI: 10.1093/Eurheartj/Ehn431  0.334
2008 Swendeman S, Mendelson K, Weskamp G, Horiuchi K, Deutsch U, Scherle P, Hooper A, Rafii S, Blobel CP. VEGF-A stimulates ADAM17-dependent shedding of VEGFR2 and crosstalk between VEGFR2 and ERK signaling. Circulation Research. 103: 916-8. PMID 18818406 DOI: 10.1161/Circresaha.108.184416  0.717
2008 Nachman RL, Rafii S. Platelets, petechiae, and preservation of the vascular wall. The New England Journal of Medicine. 359: 1261-70. PMID 18799560 DOI: 10.1056/Nejmra0800887  0.448
2008 Kerbel RS, Benezra R, Lyden DC, Hattori K, Heissig B, Nolan DJ, Mittal V, Shaked Y, Dias S, Bertolini F, Rafii S. Endothelial progenitor cells are cellular hubs essential for neoangiogenesis of certain aggressive adenocarcinomas and metastatic transition but not adenomas. Proceedings of the National Academy of Sciences of the United States of America. 105: E54; author reply E5. PMID 18715995 DOI: 10.1073/Pnas.0804876105  0.48
2008 Kim J, Seandel M, Falciatori I, Wen D, Rafii S. CD34+ testicular stromal cells support long-term expansion of embryonic and adult stem and progenitor cells. Stem Cells (Dayton, Ohio). 26: 2516-22. PMID 18669907 DOI: 10.1634/Stemcells.2008-0379  0.453
2008 James D, Rabbany S, Rafii S. Hitting the mother lode of tumor angiogenesis. Nature Biotechnology. 26: 769-70. PMID 18612297 DOI: 10.1038/Nbt0708-769  0.4
2008 Siegel AB, Cohen EI, Ocean A, Lehrer D, Goldenberg A, Knox JJ, Chen H, Clark-Garvey S, Weinberg A, Mandeli J, Christos P, Mazumdar M, Popa E, Brown RS, Rafii S, et al. Phase II trial evaluating the clinical and biologic effects of bevacizumab in unresectable hepatocellular carcinoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 2992-8. PMID 18565886 DOI: 10.1200/Jco.2007.15.9947  0.308
2008 Shmelkov SV, Butler JM, Hooper AT, Hormigo A, Kushner J, Milde T, St Clair R, Baljevic M, White I, Jin DK, Chadburn A, Murphy AJ, Valenzuela DM, Gale NW, Thurston G, ... ... Rafii S, et al. CD133 expression is not restricted to stem cells, and both CD133+ and CD133- metastatic colon cancer cells initiate tumors. The Journal of Clinical Investigation. 118: 2111-20. PMID 18497886 DOI: 10.1172/Jci34401  0.673
2008 Seandel M, Butler J, Lyden D, Rafii S. A catalytic role for proangiogenic marrow-derived cells in tumor neovascularization. Cancer Cell. 13: 181-3. PMID 18328420 DOI: 10.1016/J.Ccr.2008.02.016  0.391
2008 Wels J, Kaplan RN, Rafii S, Lyden D. Migratory neighbors and distant invaders: tumor-associated niche cells. Genes & Development. 22: 559-74. PMID 18316475 DOI: 10.1101/Gad.1636908  0.405
2008 Seandel M, Falciatori I, Shmelkov SV, Kim J, James D, Rafii S. Niche players: spermatogonial progenitors marked by GPR125. Cell Cycle (Georgetown, Tex.). 7: 135-40. PMID 18256534 DOI: 10.4161/Cc.7.2.5248  0.458
2008 Rafii S, Lyden D. Cancer. A few to flip the angiogenic switch. Science (New York, N.Y.). 319: 163-4. PMID 18187643 DOI: 10.1126/Science.1153615  0.439
2008 Naik RP, Jin D, Chuang E, Gold EG, Tousimis EA, Moore AL, Christos PJ, de Dalmas T, Donovan D, Rafii S, Vahdat LT. Circulating endothelial progenitor cells correlate to stage in patients with invasive breast cancer. Breast Cancer Research and Treatment. 107: 133-8. PMID 18043899 DOI: 10.1200/Jco.2006.24.18_Suppl.616  0.389
2008 Petit I, Karajannis MA, Vincent L, Young L, Butler J, Hooper AT, Shido K, Steller H, Chaplin DJ, Feldman E, Rafii S. The microtubule-targeting agent CA4P regresses leukemic xenografts by disrupting interaction with vascular cells and mitochondrial-dependent cell death. Blood. 111: 1951-61. PMID 18024794 DOI: 10.1182/Blood-2007-05-089219  0.707
2008 Hormigo A, Shmelkov SV, Hooper AT, Butler J, Lyden D, Rafii S. Expression of CD133+ in the brain of a mouse model with a lacZ reporter knock-in at the CD133 locus Journal of Clinical Oncology. 26: 2000-2000. DOI: 10.1200/Jco.2008.26.15_Suppl.2000  0.656
2008 Baljevic M, Shmelkov SV, Nolan DJ, Hooper AT, Hormigo A, Iyer R, Gutin PH, Rafii S. Endothelial Progenitor Cell Marker CD133 Identifies Tumor Endothelium Blood. 112: 5449-5449. DOI: 10.1182/Blood.V112.11.5449.5449  0.725
2007 Hooper AT, Butler J, Petit I, Rafii S. Does N-cadherin regulate interaction of hematopoietic stem cells with their niches? Cell Stem Cell. 1: 127-9. PMID 18371341 DOI: 10.1016/J.Stem.2007.07.012  0.693
2007 Seandel M, James D, Shmelkov SV, Falciatori I, Kim J, Chavala S, Scherr DS, Zhang F, Torres R, Gale NW, Yancopoulos GD, Murphy A, Valenzuela DM, Hobbs RM, Pandolfi PP, ... Rafii S, et al. Generation of functional multipotent adult stem cells from GPR125+ germline progenitors. Nature. 449: 346-50. PMID 17882221 DOI: 10.1038/Nature06129  0.452
2007 Petit I, Jin D, Rafii S. The SDF-1-CXCR4 signaling pathway: a molecular hub modulating neo-angiogenesis. Trends in Immunology. 28: 299-307. PMID 17560169 DOI: 10.1016/J.It.2007.05.007  0.567
2007 Kopp HG, Hooper AT, Shmelkov SV, Rafii S. Beta-galactosidase staining on bone marrow. The osteoclast pitfall. Histology and Histopathology. 22: 971-6. PMID 17523074  0.63
2007 Kopp HG, Rafii S. Thrombopoietic cells and the bone marrow vascular niche. Annals of the New York Academy of Sciences. 1106: 175-9. PMID 17395736 DOI: 10.1196/Annals.1392.004  0.416
2007 Mutlu AD, Cavallin LE, Vincent L, Chiozzini C, Eroles P, Duran EM, Asgari Z, Hooper AT, La Perle KM, Hilsher C, Gao SJ, Dittmer DP, Rafii S, Mesri EA. In vivo-restricted and reversible malignancy induced by human herpesvirus-8 KSHV: a cell and animal model of virally induced Kaposi's sarcoma. Cancer Cell. 11: 245-58. PMID 17349582 DOI: 10.1016/J.Ccr.2007.01.015  0.737
2007 Milde T, Shmelkov SV, Jensen KK, Zlotchenko G, Petit I, Rafii S. A novel family of slitrk genes is expressed on hematopoietic stem cells and leukemias. Leukemia. 21: 824-7. PMID 17268530 DOI: 10.1038/Sj.Leu.2404525  0.374
2007 Hormigo A, Gutin PH, Rafii S. Tracking normalization of brain tumor vasculature by magnetic imaging and proangiogenic biomarkers. Cancer Cell. 11: 6-8. PMID 17222788 DOI: 10.1016/J.Ccr.2006.12.008  0.378
2007 Jin D, Port JL, Lee P, Zhang L, Ferrara CA, McDonald KA, Meherally D, Rafii S, Altorki NK. Hemangiogenic response after pre-operative COX2 inhibition predicts recurrence in esophageal cancer Journal of Clinical Oncology. 25: 15077-15077. DOI: 10.1200/Jco.2007.25.18_Suppl.15077  0.344
2007 Hajjar KA, Ruan J, Sui G, Deora AB, Church S, Cohen-Gould L, Rafii S, Lyden DC, Ling Q. Annexin 2 Mediates Plasminogen-Related Recruitment of Neovascular Mural Cells in Lymphoma Angiogenesis. Blood. 110: 3708-3708. DOI: 10.1182/Blood.V110.11.3708.3708  0.459
2007 Rabbany SY, Rafii S. Cell of cells: The global race to capture and control the stem cell Journal of Clinical Investigation. 117: 2349-2349. DOI: 10.1172/Jci33079  0.377
2007 Zaninovic N, Hao J, Pareja J, James D, Rafii S, Rosenwaks Z. Genetic modification of preimplantation embryos and embryonic stem cells (ESC) by recombinant lentiviral vectors: efficient and stable method for creating transgenic embryos and ESC Fertility and Sterility. 88: S310. DOI: 10.1016/J.Fertnstert.2007.07.1043  0.325
2007 Pareja J, Zaninovic N, Hao J, Rafii S, Rosenwaks Z. Quantitative gene expression analysis of pluripotent and early differentiation genes in human preimplantation embryos at the single-cell level Fertility and Sterility. 88: S309. DOI: 10.1016/J.Fertnstert.2007.07.1039  0.314
2007 D'Agostino Mutlu A, Cavallin LE, Vincent L, Chiozzini C, Eroles P, Duran EM, Asgari Z, Hooper AT, La Perle KMD, Hilsher C, Gao SJ, Dittmer DP, Rafii S, Mesri EA. In Vivo-Restricted and Reversible Malignancy Induced by Human Herpesvirus-8 KSHV: A Cell and Animal Model of Virally Induced Kaposi's Sarcoma (DOI:10.1016/j.ccr.2007.01.015) Cancer Cell. 11: 471. DOI: 10.1016/J.Ccr.2007.04.013  0.658
2006 Kaplan RN, Rafii S, Lyden D. Preparing the "soil": the premetastatic niche. Cancer Research. 66: 11089-93. PMID 17145848 DOI: 10.1158/0008-5472.Can-06-2407  0.466
2006 Kopp HG, Hooper AT, Broekman MJ, Avecilla ST, Petit I, Luo M, Milde T, Ramos CA, Zhang F, Kopp T, Bornstein P, Jin DK, Marcus AJ, Rafii S. Thrombospondins deployed by thrombopoietic cells determine angiogenic switch and extent of revascularization. The Journal of Clinical Investigation. 116: 3277-91. PMID 17143334 DOI: 10.1172/Jci29314  0.803
2006 Rafii S, Lyden D. S100 chemokines mediate bookmarking of premetastatic niches. Nature Cell Biology. 8: 1321-3. PMID 17139281 DOI: 10.1038/Ncb1206-1321  0.455
2006 Ruan J, Hyjek E, Kermani P, Christos PJ, Hooper AT, Coleman M, Hempstead B, Leonard JP, Chadburn A, Rafii S. Magnitude of stromal hemangiogenesis correlates with histologic subtype of non-Hodgkin's lymphoma Clinical Cancer Research. 12: 5622-5631. PMID 17020964 DOI: 10.1158/1078-0432.Ccr-06-1204  0.704
2006 Bernardi R, Guernah I, Jin D, Grisendi S, Alimonti A, Teruya-Feldstein J, Cordon-Cardo C, Simon MC, Rafii S, Pandolfi PP. PML inhibits HIF-1alpha translation and neoangiogenesis through repression of mTOR. Nature. 442: 779-85. PMID 16915281 DOI: 10.1038/Nature05029  0.358
2006 Wu Y, Hooper AT, Zhong Z, Witte L, Bohlen P, Rafii S, Hicklin DJ. The vascular endothelial growth factor receptor (VEGFR-1) supports growth and survival of human breast carcinoma. International Journal of Cancer. 119: 1519-29. PMID 16671089 DOI: 10.1002/Ijc.21865  0.709
2006 Cher ML, Towler DA, Rafii S, Rowley D, Donahue HJ, Keller E, Herlyn M, Cho EA, Chung LW. Cancer interaction with the bone microenvironment: a workshop of the National Institutes of Health Tumor Microenvironment Study Section. The American Journal of Pathology. 168: 1405-12. PMID 16651608 DOI: 10.2353/Ajpath.2006.050874  0.413
2006 Jin DK, Shido K, Kopp HG, Petit I, Shmelkov SV, Young LM, Hooper AT, Amano H, Avecilla ST, Heissig B, Hattori K, Zhang F, Hicklin DJ, Wu Y, Zhu Z, ... ... Rafii S, et al. Cytokine-mediated deployment of SDF-1 induces revascularization through recruitment of CXCR4+ hemangiocytes. Nature Medicine. 12: 557-67. PMID 16648859 DOI: 10.1038/Nm1400  0.784
2006 Karajannis MA, Vincent L, Direnzo R, Shmelkov SV, Zhang F, Feldman EJ, Bohlen P, Zhu Z, Sun H, Kussie P, Rafii S. Activation of FGFR1beta signaling pathway promotes survival, migration and resistance to chemotherapy in acute myeloid leukemia cells. Leukemia. 20: 979-86. PMID 16598308 DOI: 10.1038/Sj.Leu.2404203  0.414
2006 Kopp HG, Ramos CA, Rafii S. Contribution of endothelial progenitors and proangiogenic hematopoietic cells to vascularization of tumor and ischemic tissue Current Opinion in Hematology. 13: 175-181. PMID 16567962 DOI: 10.1097/01.Moh.0000219664.26528.Da  0.572
2006 Vincent L, Avancena P, Cheng J, Rafii S, Rabbany SY. Simulated microgravity impairs leukemic cell survival through altering VEGFR-2/VEGF-A signaling pathway. Annals of Biomedical Engineering. 33: 1405-10. PMID 16240088 DOI: 10.1007/S10439-005-6153-5  0.479
2006 Kopp H, Hooper AT, Rafii S. Bone Marrow Osteoclasts Stain Positive with X-Gal: Implications for the Tracking of LacZ-Labelled Cells. Blood. 108: 4173-4173. DOI: 10.1182/Blood.V108.11.4173.4173  0.667
2006 Ruan J, Coleman M, Furman RR, Glynn P, Joyce M, Ketas J, Cheung K, Church S, Shore T, Feldman E, Rutherford S, Hyjek E, Chadburn A, Rafii S, Leonard JP. Targeting Angiogenesis in Mantle Cell Lymphoma: Clinical Efficacy and Correlative Studies of a Phase II Trial of RT-PEPC (Rituximab, Thalidomide and Metronomic Oral Chemotherapy with Prednisone, Etoposide, Procarbazine and Cyclophosphamide) in Relapsed/Refractory Disease. Blood. 108: 2751-2751. DOI: 10.1182/Blood.V108.11.2751.2751  0.33
2006 Petit I, Kaul P, Lerner DJ, Rafii S. The GEF Lsc Regulates Hematopoietic Stem Cell Motility, Mobilization and Recruitment. Blood. 108: 1346-1346. DOI: 10.1182/Blood.V108.11.1346.1346  0.519
2006 Jin DK, Shido K, Kopp H, Petit I, Shmelkov SV, Young LM, Hooper AT, Amano H, Avecilla ST, Heissig B, Hattori K, Zhang F, Hicklin DJ, Wu Y, Zhu Z, ... ... Rafii S, et al. Erratum: Corrigendum: Cytokine-mediated deployment of SDF-1 induces revascularization through recruitment of CXCR4+ hemangiocytes Nature Medicine. 12: 978-978. DOI: 10.1038/Nm0806-978  0.747
2005 Hooper AT, Akiri G, Jin D, Shmelkov SV, Chuang E, Shin SJ, Wu Y, Hicklin DJ, Rafii S, Vahdat LT. VEGF receptor expression on reactive breast cancer stroma: paving the way for tumor invasion. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 23: 9642. PMID 27943777 DOI: 10.1200/Jco.2005.23.16_Suppl.9642  0.687
2005 Kaplan RN, Riba RD, Zacharoulis S, Bramley AH, Vincent L, Costa C, MacDonald DD, Jin DK, Shido K, Kerns SA, Zhu Z, Hicklin D, Wu Y, Port JL, Altorki N, ... ... Rafii S, et al. VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche. Nature. 438: 820-7. PMID 16341007 DOI: 10.1038/Nature04186  0.473
2005 Feugier P, Li N, Jo DY, Shieh JH, MacKenzie KL, Lesesve JF, Latger-Cannard V, Bensoussan D, Crystal RG, Rafii S, Stoltz JF, Moore MA. Osteopetrotic mouse stroma with thrombopoietin, c-kit ligand, and flk-2 ligand supports long-term mobilized CD34+ hematopoiesis in vitro. Stem Cells and Development. 14: 505-16. PMID 16305336 DOI: 10.1089/Scd.2005.14.505  0.418
2005 Vincent L, Kermani P, Young LM, Cheng J, Zhang F, Shido K, Lam G, Bompais-Vincent H, Zhu Z, Hicklin DJ, Bohlen P, Chaplin DJ, May C, Rafii S. Combretastatin A4 phosphate induces rapid regression of tumor neovessels and growth through interference with vascular endothelial-cadherin signaling. The Journal of Clinical Investigation. 115: 2992-3006. PMID 16224539 DOI: 10.1172/Jci24586  0.471
2005 Kopp HG, Avecilla ST, Hooper AT, Rafii S. The bone marrow vascular niche: home of HSC differentiation and mobilization. Physiology (Bethesda, Md.). 20: 349-56. PMID 16174874 DOI: 10.1152/Physiol.00025.2005  0.796
2005 Heissig B, Rafii S, Akiyama H, Ohki Y, Sato Y, Rafael T, Zhu Z, Hicklin DJ, Okumura K, Ogawa H, Werb Z, Hattori K. Low-dose irradiation promotes tissue revascularization through VEGF release from mast cells and MMP-9-mediated progenitor cell mobilization Journal of Experimental Medicine. 202: 739-750. PMID 16157686 DOI: 10.1084/Jem.20050959  0.515
2005 Amano H, Hackett NR, Rafii S, Crystal RG. Thrombopoietin gene transfer-mediated enhancement of angiogenic responses to acute ischemia Circulation Research. 97: 337-345. PMID 16051888 DOI: 10.1161/01.Res.0000179534.17668.F8  0.336
2005 Heissig B, Ohki Y, Sato Y, Rafii S, Werb Z, Hattori K. A role for niches in hematopoietic cell development Hematology. 10: 247-253. PMID 16019473 DOI: 10.1080/10245330500067249  0.442
2005 Vidal A, Zacharoulis S, Guo W, Shaffer D, Giancotti F, Bramley AH, de la Hoz C, Jensen KK, Kato D, MacDonald DD, Knowles J, Yeh N, Frohman LA, Rafii S, Lyden D, et al. p130Rb2 and p27kip1 cooperate to control mobilization of angiogenic progenitors from the bone marrow. Proceedings of the National Academy of Sciences of the United States of America. 102: 6890-5. PMID 15867156 DOI: 10.1073/Pnas.0405823102  0.513
2005 Vincent L, Jin DK, Karajannis MA, Shido K, Hooper AT, Rashbaum WK, Pytowski B, Wu Y, Hicklin DJ, Zhu Z, Bohlen P, Niesvizky R, Rafii S. Fetal stromal-dependent paracrine and intracrine vascular endothelial growth factor-a/vascular endothelial growth factor receptor-1 signaling promotes proliferation and motility of human primary myeloma cells. Cancer Research. 65: 3185-92. PMID 15833849 DOI: 10.1158/0008-5472.Can-04-3598  0.755
2005 Zhang F, Cheng J, Lam G, Jin DK, Vincent L, Hackett NR, Wang S, Young LM, Hempstead B, Crystal RG, Rafii S. Adenovirus vector E4 gene regulates connexin 40 and 43 expression in endothelial cells via PKA and PI3K signal pathways. Circulation Research. 96: 950-7. PMID 15831817 DOI: 10.1161/01.Res.0000165867.95291.7B  0.406
2005 Kopp HG, Avecilla ST, Hooper AT, Shmelkov SV, Ramos CA, Zhang F, Rafii S. Tie2 activation contributes to hemangiogenic regeneration after myelosuppression. Blood. 106: 505-13. PMID 15817675 DOI: 10.1182/Blood-2004-11-4269  0.817
2005 Kermani P, Rafii D, Jin DK, Whitlock P, Schaffer W, Chiang A, Vincent L, Friedrich M, Shido K, Hackett NR, Crystal RG, Rafii S, Hempstead BL. Neurotrophins promote revascularization by local recruitment of TrkB+ endothelial cells and systemic mobilization of hematopoietic progenitors. The Journal of Clinical Investigation. 115: 653-63. PMID 15765148 DOI: 10.1172/jci22655  0.484
2005 Shmelkov SV, Meeus S, Moussazadeh N, Kermani P, Rashbaum WK, Rabbany SY, Hanson MA, Lane WJ, St Clair R, Walsh KA, Dias S, Jacobson JT, Hempstead BL, Edelberg JM, Rafii S. Cytokine preconditioning promotes codifferentiation of human fetal liver CD133+ stem cells into angiomyogenic tissue. Circulation. 111: 1175-83. PMID 15753226 DOI: 10.1161/01.Cir.0000157155.44008.0F  0.454
2005 Shmelkov SV, Clair RS, Lyden D, Rafii S. AC133/CD133/Prominin-1 International Journal of Biochemistry and Cell Biology. 37: 715-719. PMID 15694831 DOI: 10.1016/J.Biocel.2004.08.010  0.463
2005 Jin DK, Young LM, Vincent L, Gelbshtein U, Pekle K, Lam G, Shido K, Cho HJ, Pearse R, Leonard JP, Chen-Kiang S, Coleman M, Rafii S, Niesvizky R. Multimodular Analysis of Angiogenic Biomarkers in the Primary Treatment of Multiple Myeloma: Correlative Studies of the BiRD Trial. Blood. 106: 3483-3483. DOI: 10.1182/Blood.V106.11.3483.3483  0.374
2005 Ellis LR, Vincent L, Shmelkov S, Hooper A, Avecilla S, Young L, Rafii S. Expression of Vascular Endothelial-Cadherin on Leukemic Cells Mediates Their Interaction with Vascular Endothelium. Blood. 106: 2761-2761. DOI: 10.1182/Blood.V106.11.2761.2761  0.827
2005 Ruan J, Hyjek E, Hooper AT, Vincent L, Kermani P, Christos PJ, Ikalowych S, Coleman M, Hempstead B, Leonard JP, Chadburn A, Rafii S. Stromal Incorporation of VEGFR-1+, CD68+ and α-SMA+ Hemangiogenic Cells Correlates with Histologic Subtype in Non-Hodgkin’s Lymphoma. Blood. 106: 1930-1930. DOI: 10.1182/Blood.V106.11.1930.1930  0.688
2004 Vincent L, Rafii S. Vascular frontiers without borders: multifaceted roles of platelet-derived growth factor (PDGF) in supporting postnatal angiogenesis and lymphangiogenesis. Cancer Cell. 6: 307-9. PMID 15488752 DOI: 10.1016/J.Ccr.2004.09.024  0.392
2004 Silver RT, Bennett JM, Deininger M, Feldman E, Rafii S, Silverstein RL, Solberg LA, Spivak JL. The second international congress on myeloproliferative and myelodysplastic syndromes. Leukemia Research. 28: 979-85. PMID 15234576 DOI: 10.1016/J.Leukres.2004.01.012  0.48
2004 Moldenhauer A, Nociari M, Lam G, Salama A, Rafii S, Moore MA. Tumor necrosis factor alpha-stimulated endothelium: an inducer of dendritic cell development from hematopoietic progenitors and myeloid leukemic cells. Stem Cells (Dayton, Ohio). 22: 144-57. PMID 14990854 DOI: 10.1634/Stemcells.22-2-144  0.432
2004 Xaymardan M, Tang L, Zagreda L, Pallante B, Zheng J, Chazen JL, Chin A, Duignan I, Nahirney P, Rafii S, Mikawa T, Edelberg JM. Platelet-derived growth factor-AB promotes the generation of adult bone marrow-derived cardiac myocytes. Circulation Research. 94: E39-45. PMID 14963008 DOI: 10.1161/01.Res.0000122042.51161.B6  0.337
2004 Avecilla ST, Hattori K, Heissig B, Tejada R, Liao F, Shido K, Jin DK, Dias S, Zhang F, Hartman TE, Hackett NR, Crystal RG, Witte L, Hicklin DJ, Bohlen P, ... ... Rafii S, et al. Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis. Nature Medicine. 10: 64-71. PMID 14702636 DOI: 10.1038/Nm973  0.753
2004 Shmelkov SV, Jun L, St Clair R, McGarrigle D, Derderian CA, Usenko JK, Costa C, Zhang F, Guo X, Rafii S. Alternative promoters regulate transcription of the gene that encodes stem cell surface protein AC133. Blood. 103: 2055-61. PMID 14630820 DOI: 10.1182/Blood-2003-06-1881  0.416
2004 Hattori K, Ohki Y, Sato Y, Rafii S, Werb Z, Heissig B. Low-Dose Irradiation Promotes Tissue Revascularization through Matrix Metalloproteinase-9 Mediated VEGF Release from Mast Cells. Blood. 104: 648-648. DOI: 10.1182/Blood.V104.11.648.648  0.49
2004 Cheng J, Zhang F, Lam G, Hackett NR, Wang S, Amano H, Shmelkov SV, Young LM, Hempstead B, Crystal RG, Rafii S. Adenovirus Vector E4 Gene Promotes Angiogenesis through Modulation of Junctional Connexin 40 and 43 Expression. Blood. 104: 5277-5277. DOI: 10.1182/Blood.V104.11.5277.5277  0.428
2004 Karajannis MA, Vincent L, Zhang F, Shmelkov SV, Cheung J, Bohlen P, Zhu Z, Kussie P, Sun H, Rafii S. Fibroblast Growth Factor Receptor-1 Expression and Signaling in Acute Myeloid Leukemia. Blood. 104: 4477-4477. DOI: 10.1182/Blood.V104.11.4477.4477  0.39
2004 Shmelkov SV, St.Clair R, Jun L, Calderone A, Karajannis MA, Jensen KK, Young LM, Walsh K, Shido K, Jin D, Zhang F, Cheng J, Lam G, Tejada R, Avecilla ST, ... ... Rafii S, et al. Newly Discovered Polymorphism in the CD34+ Stem Cell Specific AC133-P1 Promoter Linked to Leukemias. Blood. 104: 2002-2002. DOI: 10.1182/Blood.V104.11.2002.2002  0.698
2004 Kopp H, Avecilla ST, Tejada R, Crystal RG, Hackett NR, Rafii S. Tie-2 Activation Is Required for Regeneration of Marrow Vasculature, Supporting Hematopoietic Reconstitution. Blood. 104: 1297-1297. DOI: 10.1182/Blood.V104.11.1297.1297  0.745
2004 Amano H, Hackett NR, Shido K, Tejada R, Avegilla S, Rafii S, Crystal RG. 196. Regional Angiogenesis Mediated by Platelet-Derived VEGF in Response to Thrombopoietin Gene Transfer Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.104  0.416
2003 Rafii S, Avecilla ST, Jin DK. Tumor vasculature address book: identification of stage-specific tumor vessel zip codes by phage display. Cancer Cell. 4: 331-3. PMID 14667498 DOI: 10.1016/S1535-6108(03)00278-2  0.676
2003 Zhang F, Cheng J, Hackett NR, Lam G, Shido K, Pergolizzi R, Jin DK, Crystal RG, Rafii S. Adenovirus E4 gene promotes selective endothelial cell survival and angiogenesis via activation of the vascular endothelial-cadherin/Akt signaling pathway. The Journal of Biological Chemistry. 279: 11760-6. PMID 14660586 DOI: 10.1074/Jbc.M312221200  0.376
2003 Ruzinova MB, Schoer RA, Gerald W, Egan JE, Pandolfi PP, Rafii S, Manova K, Mittal V, Benezra R. Effect of angiogenesis inhibition by Id loss and the contribution of bone-marrow-derived endothelial cells in spontaneous murine tumors. Cancer Cell. 4: 277-89. PMID 14585355 DOI: 10.1016/S1535-6108(03)00240-X  0.438
2003 Heissig B, Werb Z, Rafii S, Hattori K. Role of c-kit/Kit ligand signaling in regulating vasculogenesis Thrombosis and Haemostasis. 90: 570-576. PMID 14515175 DOI: 10.1160/Th03-03-0188  0.566
2003 Edelberg JM, Xaymardan M, Rafii S, Hong MK. Adult cardiac stem cells--where do we go from here? Science of Aging Knowledge Environment. 2003: 17. PMID 12844537 DOI: 10.1126/Sageke.2003.26.Pe17  0.419
2003 Zhang F, Hackett NR, Lam G, Cheng J, Pergolizzi R, Luo L, Shmelkov SV, Edelberg J, Crystal RG, Rafii S. Green fluorescent protein selectively induces HSP70-mediated up-regulation of COX-2 expression in endothelial cells. Blood. 102: 2115-21. PMID 12805066 DOI: 10.1182/Blood-2003-01-0049  0.413
2003 Rafii S, Avecilla S, Shmelkov S, Shido K, Tejada R, Moore MA, Heissig B, Hattori K. Angiogenic factors reconstitute hematopoiesis by recruiting stem cells from bone marrow microenvironment. Annals of the New York Academy of Sciences. 996: 49-60. PMID 12799282 DOI: 10.1111/J.1749-6632.2003.Tb03232.X  0.769
2003 Rafii S, Lyden D. Therapeutic stem and progenitor cell transplantation for organ vascularization and regeneration. Nature Medicine. 9: 702-12. PMID 12778169 DOI: 10.1038/Nm0603-702  0.537
2003 Hattori K, Heissig B, Rafii S. The regulation of hematopoietic stem cell and progenitor mobilization by chemokine SDF-1. Leukemia & Lymphoma. 44: 575-82. PMID 12769333 DOI: 10.1080/1042819021000037985  0.487
2003 Garcia-Barros M, Paris F, Cordon-Cardo C, Lyden D, Rafii S, Haimovitz-Friedman A, Fuks Z, Kolesnick R. Tumor response to radiotherapy regulated by endothelial cell apoptosis. Science (New York, N.Y.). 300: 1155-9. PMID 12750523 DOI: 10.1126/Science.1082504  0.377
2003 Rabbany SY, Heissig B, Hattori K, Rafii S. Molecular pathways regulating mobilization of marrow-derived stem cells for tissue revascularization. Trends in Molecular Medicine. 9: 109-17. PMID 12657432 DOI: 10.1016/S1471-4914(03)00021-2  0.558
2003 Zhu Z, Hattori K, Zhang H, Jimenez X, Ludwig DL, Dias S, Kussie P, Koo H, Kim HJ, Lu D, Liu M, Tejada R, Friedrich M, Bohlen P, Witte L, ... Rafii S, et al. Inhibition of human leukemia in an animal model with human antibodies directed against vascular endothelial growth factor receptor 2. Correlation between antibody affinity and biological activity. Leukemia. 17: 604-11. PMID 12646950 DOI: 10.1038/Sj.Leu.2402831  0.427
2003 Bais C, Van Geelen A, Eroles P, Mutlu A, Chiozzini C, Dias S, Silverstein RL, Rafii S, Mesri EA. Kaposi's sarcoma associated herpesvirus G protein-coupled receptor immortalizes human endothelial cells by activation of the VEGF receptor-2/ KDR. Cancer Cell. 3: 131-43. PMID 12620408 DOI: 10.1016/S1535-6108(03)00024-2  0.469
2003 Heissig B, Hattori K, Friedrich M, Rafii S, Werb Z. Angiogenesis: Vascular remodeling of the extracellular matrix involves metalloproteinases Current Opinion in Hematology. 10: 136-141. PMID 12579040 DOI: 10.1097/00062752-200303000-00007  0.375
2003 Rafii S, Skobe M. Splitting vessels: keeping lymph apart from blood. Nature Medicine. 9: 166-8. PMID 12563334 DOI: 10.1038/Nm0203-166  0.373
2003 Rafii S. Vaccination against tumor neovascularization: Promise and reality. Cancer Cell. 2: 429-31. PMID 12498709 DOI: 10.1016/S1535-6108(02)00208-8  0.33
2003 Rafii S, Lyden D. Therapeutic stem and progenitor cell transplantation for organ vascularization and regeneration American Journal of Ophthalmology. 136: 1198. DOI: 10.1016/J.Ajo.2003.09.026  0.535
2002 Pintucci G, Froum S, Pinnell J, Mignatti P, Rafii S, Green D. Trophic effects of platelets on cultured endothelial cells are mediated by platelet-associated fibroblast growth factor-2 (FGF-2) and vascular endothelial growth factor (VEGF). Thrombosis and Haemostasis. 88: 834-42. PMID 12428103 DOI: 10.1267/th02110834  0.331
2002 Rafii S, Lyden D, Benezra R, Hattori K, Heissig B. Vascular and haematopoietic stem cells: novel targets for anti-angiogenesis therapy? Nature Reviews. Cancer. 2: 826-35. PMID 12415253 DOI: 10.1038/Nrc925  0.545
2002 Salven P, Mustjoki S, Alitalo R, Alitalo K, Rafii S. VEGFR-3 and CD133 identify a population of CD34+ lymphatic/vascular endothelial precursor cells. Blood. 101: 168-72. PMID 12393704 DOI: 10.1182/Blood-2002-03-0755  0.462
2002 Salven P, Hattori K, Heissig B, Rafii S. Interleukin-1alpha promotes angiogenesis in vivo via VEGFR-2 pathway by inducing inflammatory cell VEGF synthesis and secretion. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 1471-3. PMID 12205052 DOI: 10.1096/Fj.02-0134Fje  0.429
2002 Wijelath ES, Murray J, Rahman S, Patel Y, Ishida A, Strand K, Aziz S, Cardona C, Hammond WP, Savidge GF, Rafii S, Sobel M. Novel vascular endothelial growth factor binding domains of fibronectin enhance vascular endothelial growth factor biological activity Circulation Research. 91: 25-31. PMID 12114318 DOI: 10.1161/01.Res.0000026420.22406.79  0.441
2002 Hattori K, Heissig B, Wu Y, Dias S, Tejada R, Ferris B, Hicklin DJ, Zhu Z, Bohlen P, Witte L, Hendrikx J, Hackett NR, Crystal RG, Moore MAS, Werb Z, ... ... Rafii S, et al. Placental growth factor reconstitutes hematopoiesis by recruiting VEGFR1+ stem cells from bone-marrow microenvironment Nature Medicine. 8: 841-849. PMID 12091880 DOI: 10.1038/Nm740  0.554
2002 MacKenzie KL, Franco S, Naiyer AJ, May C, Sadelain M, Rafii S, Moore MA. Multiple stages of malignant transformation of human endothelial cells modelled by co-expression of telomerase reverse transcriptase, SV40 T antigen and oncogenic N-ras. Oncogene. 21: 4200-11. PMID 12082607 DOI: 10.1038/Sj.Onc.1205425  0.389
2002 Heissig B, Hattori K, Dias S, Friedrich M, Ferris B, Hackett NR, Crystal RG, Besmer P, Lyden D, Moore MAS, Werb Z, Rafii S. Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of Kit-ligand Cell. 109: 625-637. PMID 12062105 DOI: 10.1016/S0092-8674(02)00754-7  0.458
2002 Edelberg JM, Tang L, Hattori K, Lyden D, Rafii S. Young adult bone marrow-derived endothelial precursor cells restore aging-impaired cardiac angiogenic function. Circulation Research. 90: E89-93. PMID 12039806 DOI: 10.1161/01.Res.0000020861.20064.7E  0.405
2002 Rafii S, Heissig B, Hattori K. Efficient mobilization and recruitment of marrow-derived endothelial and hematopoietic stem cells by adenoviral vectors expressing angiogenic factors. Gene Therapy. 9: 631-41. PMID 12032709 DOI: 10.1038/Sj.Gt.3301723  0.54
2002 Rafii S, Meeus S, Dias S, Hattori K, Heissig B, Shmelkov S, Rafii D, Lyden D. Contribution of marrow-derived progenitors to vascular and cardiac regeneration. Seminars in Cell & Developmental Biology. 13: 61-7. PMID 11969372 DOI: 10.1006/Scdb.2001.0285  0.535
2002 Dias S, Shmelkov SV, Lam G, Rafii S. VEGF165 promotes survival of leukemic cells by Hsp90-mediated induction of Bcl-2 expression and apoptosis inhibition Blood. 99: 2532-2540. PMID 11895790 DOI: 10.1182/Blood.V99.7.2532  0.47
2002 Dias S, Choy M, Alitalo K, Rafii S. Vascular endothelial growth factor (VEGF)-C signaling through FLT-4 (VEGFR-3) mediates leukemic cell proliferation, survival, and resistance to chemotherapy. Blood. 99: 2179-84. PMID 11877295 DOI: 10.1182/Blood.V99.6.2179  0.497
2002 Feugier P, Jo DY, Shieh JH, MacKenzie KL, Rafii S, Crystal RG, Moore MA. Ex vivo expansion of stem and progenitor cells in co-culture of mobilized peripheral blood CD34+ cells on human endothelium transfected with adenovectors expressing thrombopoietin, c-kit ligand, and Flt-3 ligand. Journal of Hematotherapy & Stem Cell Research. 11: 127-38. PMID 11847009 DOI: 10.1089/152581602753448595  0.458
2002 Benezra R, Rafii S, Lyden D. The Id proteins and angiogenesis. Oncogene. 20: 8334-41. PMID 11840326 DOI: 10.1038/Sj.Onc.1205160  0.337
2002 Kim J, Wu H, Hawthorne L, Rafii S, Laurence J. Endothelial cell apoptotic genes associated with the pathogenesis of thrombotic microangiopathies: an application of oligonucleotide genechip technology. Microvascular Research. 62: 83-93. PMID 11516238 DOI: 10.1006/Mvre.2001.2326  0.41
2002 Pintucci G, Froum S, Pinnell J, Mignatti P, Rafii S, Green D. Trophic Effects of Platelets on Cultured Endothelial Cells are Mediated by Platelet-associated Fibroblast Growth Factor-2 (FGF-2) and Vascular Endothelial Growth Factor (VEGF) Thrombosis and Haemostasis. 88: 834-842. DOI: 10.1055/S-0037-1613311  0.476
2001 Lyden D, Hattori K, Dias S, Costa C, Blaikie P, Butros L, Chadburn A, Heissig B, Marks W, Witte L, Wu Y, Hicklin D, Zhu Z, Hackett NR, Crystal RG, ... ... Rafii S, et al. Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth. Nature Medicine. 7: 1194-201. PMID 11689883 DOI: 10.1038/Nm1101-1194  0.495
2001 Dias S, Choy M, Rafii S. The role of CXC chemokines in the regulation of tumor angiogenesis. Cancer Investigation. 19: 732-8. PMID 11577814 DOI: 10.1081/Cnv-100106148  0.329
2001 Dias S, Hattori K, Heissig B, Zhu Z, Wu Y, Witte L, Hicklin DJ, Tateno M, Bohlen P, Moore MA, Rafii S. Inhibition of both paracrine and autocrine VEGF/ VEGFR-2 signaling pathways is essential to induce long-term remission of xenotransplanted human leukemias. Proceedings of the National Academy of Sciences of the United States of America. 98: 10857-62. PMID 11553814 DOI: 10.1073/Pnas.191117498  0.48
2001 Franco S, MacKenzie KL, Dias S, Alvarez S, Rafii S, Moore MA. Clonal variation in phenotype and life span of human embryonic fibroblasts (MRC-5) transduced with the catalytic component of telomerase (hTERT). Experimental Cell Research. 268: 14-25. PMID 11461114 DOI: 10.1006/Excr.2001.5264  0.374
2001 Moore MA, Hattori K, Heissig B, Shieh JH, Dias S, Crystal RG, Rafii S. Mobilization of endothelial and hematopoietic stem and progenitor cells by adenovector-mediated elevation of serum levels of SDF-1, VEGF, and angiopoietin-1. Annals of the New York Academy of Sciences. 938: 36-45; discussion 45. PMID 11458524 DOI: 10.1111/J.1749-6632.2001.Tb03572.X  0.569
2001 Dimitroff CJ, Lee JY, Rafii S, Fuhlbrigge RC, Sackstein R. CD44 is a major E-selectin ligand on human hematopoietic progenitor cells. The Journal of Cell Biology. 153: 1277-86. PMID 11402070 DOI: 10.1083/Jcb.153.6.1277  0.361
2001 Hattori K, Heissig B, Tashiro K, Honjo T, Tateno M, Shieh JH, Hackett NR, Quitoriano MS, Crystal RG, Rafii S, Moore MA. Plasma elevation of stromal cell-derived factor-1 induces mobilization of mature and immature hematopoietic progenitor and stem cells. Blood. 97: 3354-60. PMID 11369624 DOI: 10.1182/Blood.V97.11.3354  0.495
2001 Hattori K, Dias S, Heissig B, Hackett NR, Lyden D, Tateno M, Hicklin DJ, Zhu Z, Witte L, Crystal RG, Moore MA, Rafii S. Vascular endothelial growth factor and angiopoietin-1 stimulate postnatal hematopoiesis by recruitment of vasculogenic and hematopoietic stem cells. The Journal of Experimental Medicine. 193: 1005-14. PMID 11342585 DOI: 10.1084/Jem.193.9.1005  0.519
2001 Choy M, Rafii S. Role of angiogenesis in the progression and treatment of prostate cancer. Cancer Investigation. 19: 181-91. PMID 11296622 DOI: 10.1081/Cnv-100000152  0.363
2001 Gill M, Dias S, Hattori K, Rivera ML, Hicklin D, Witte L, Girardi L, Yurt R, Himel H, Rafii S. Vascular trauma induces rapid but transient mobilization of VEGFR2(+)AC133(+) endothelial precursor cells. Circulation Research. 88: 167-74. PMID 11157668 DOI: 10.1161/01.Res.88.2.167  0.488
2000 Lane WJ, Dias S, Hattori K, Heissig B, Choy M, Rabbany SY, Wood J, Moore MA, Rafii S. Stromal-derived factor 1-induced megakaryocyte migration and platelet production is dependent on matrix metalloproteinases. Blood. 96: 4152-9. PMID 11110686 DOI: 10.1182/Blood.V96.13.4152.H8004152_4152_4159  0.333
2000 Ramalingam R, Worgall S, Rafii S, Crystal RG. Downregulation of CXCR4 gene expression in primary human endothelial cells following infection with E1(-)E4(+) adenovirus gene transfer vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 2: 381-6. PMID 11020354 DOI: 10.1006/Mthe.2000.0131  0.376
2000 Möhle R, Rafii S, Moore MA. The role of endothelium in the regulation of hematopoietic stem cell migration. Stem Cells (Dayton, Ohio). 159-65. PMID 11012158 DOI: 10.1002/Stem.5530160819  0.556
2000 Dias S, Hattori K, Zhu Z, Heissig B, Choy M, Lane W, Wu Y, Chadburn A, Hyjek E, Gill M, Hicklin DJ, Witte L, Moore MA, Rafii S. Autocrine stimulation of VEGFR-2 activates human leukemic cell growth and migration. The Journal of Clinical Investigation. 106: 511-21. PMID 10953026 DOI: 10.1172/Jci8978  0.56
2000 Bautz F, Rafii S, Kanz L, Möhle R. Expression and secretion of vascular endothelial growth factor-A by cytokine-stimulated hematopoietic progenitor cells. Possible role in the hematopoietic microenvironment. Experimental Hematology. 28: 700-6. PMID 10880756 DOI: 10.1016/S0301-472X(00)00168-5  0.557
2000 Jo DY, Rafii S, Hamada T, Moore MA. Chemotaxis of primitive hematopoietic cells in response to stromal cell-derived factor-1. The Journal of Clinical Investigation. 105: 101-11. PMID 10619866 DOI: 10.1172/Jci7954  0.424
2000 Rafii S. Circulating endothelial precursors: mystery, reality, and promise. The Journal of Clinical Investigation. 105: 17-9. PMID 10619857 DOI: 10.1172/Jci8774  0.575
2000 Roboz GJ, Dias S, Lam G, Lane WJ, Soignet SL, Warrell RP, Rafii S. Arsenic trioxide induces dose- and time-dependent apoptosis of endothelium and may exert an antileukemic effect via inhibition of angiogenesis Blood. 96: 1525-1530. DOI: 10.1182/Blood.V96.4.1525.H8001525_1525_1530  0.528
2000 Peichev M, Naiyer AJ, Pereira D, Zhu Z, Lane WJ, Williams M, Oz MC, Hicklin DJ, Witte L, Moore MAS, Rafii S. Expression of VEGFR-2 and AC133 by circulating human CD34+ cells identifies a population of functional endothelial precursors Blood. 95: 952-958. DOI: 10.1182/Blood.V95.3.952.003K27_952_958  0.516
1999 Naiyer AJ, Jo DY, Ahn J, Mohle R, Peichev M, Lam G, Silverstein RL, Moore MAS, Rafii S. Stromal derived factor-1-induced chemokinesis of cord blood CD34+ cells (long-term culture-initiating cells) through endothelial cells is mediated by E-selectin Blood. 94: 4011-4019. PMID 10590044 DOI: 10.1182/Blood.V94.12.4011  0.457
1999 Ramalingam R, Rafii S, Worgall S, Hackett NR, Crystal RG. Induction of endogenous genes following infection of human endothelial cells with an E1(-) E4(+) adenovirus gene transfer vector. Journal of Virology. 73: 10183-90. PMID 10559334 DOI: 10.1128/Jvi.73.12.10183-10190.1999  0.367
1999 Leventhal C, Rafii S, Rafii D, Shahar A, Goldman SA. Endothelial trophic support of neuronal production and recruitment from the adult mammalian subependyma. Molecular and Cellular Neurosciences. 13: 450-64. PMID 10383830 DOI: 10.1006/Mcne.1999.0762  0.412
1999 Möhle R, Bautz F, Rafii S, Moore MA, Brugger W, Kanz L. Regulation of transendothelial migration of hematopoietic progenitor cells. Annals of the New York Academy of Sciences. 872: 176-85; discussion 1. PMID 10372121 DOI: 10.1111/J.1749-6632.1999.Tb08463.X  0.548
1999 Roboz GJ, Rafii S. Interleukin-5 and the regulation of eosinophil production. Current Opinion in Hematology. 6: 164-8. PMID 10226737 DOI: 10.1097/00062752-199905000-00007  0.332
1999 Ramalingam R, Rafii S, Worgall S, Brough DE, Crystal RG. E1(-)E4(+) adenoviral gene transfer vectors function as a "pro-life" signal to promote survival of primary human endothelial cells. Blood. 93: 2936-2944. DOI: 10.1182/Blood.V93.9.2936.409A14_2936_2944  0.431
1999 Ramalingam R, Rafii S, Worgall S, Brough DE, Crystal RG. E1−E4+ Adenoviral Gene Transfer Vectors Function as a “Pro-Life” Signal to Promote Survival of Primary Human Endothelial Cells Blood. 93: 2936-2944. DOI: 10.1182/blood.v93.9.2936  0.333
1999 Nikolovska S, Naiyer AJ, Flore O, Peichev M, Witte L, Rafii S, Cesarman E. IN VITRO INHIBITION OF KSHV/HHV-8 INFECTED ENDOTHELIAL CELL GROWTH BY NEUTRALIZING MONOCLONAL ANTIBODIES TO HUMAN VEGFR-2 (KDR) Jaids: Journal of Acquired Immune Deficiency Syndromes. 21: A28. DOI: 10.1097/00126334-199905010-00096  0.395
1998 Flore O, Rafii S, Ely S, O'Leary JJ, Hyjek EM, Cesarman E. Transformation of primary human endothelial cells by Kaposi's sarcoma-associated herpesvirus. Nature. 394: 588-92. PMID 9707121 DOI: 10.1038/29093  0.459
1998 Hamada T, Möhle R, Hesselgesser J, Hoxie J, Nachman RL, Moore MAS, Rafii S. Transendothelial migration of megakaryocytes in response to stromal cell-derived factor 1 (SDF-1) enhances platelet formation Journal of Experimental Medicine. 188: 539-548. PMID 9687531 DOI: 10.1084/Jem.188.3.539  0.425
1998 Shi Q, Rafii S, Wu MH, Wijelath ES, Yu C, Ishida A, Fujita Y, Kothari S, Mohle R, Sauvage LR, Moore MA, Storb RF, Hammond WP. Evidence for circulating bone marrow-derived endothelial cells. Blood. 92: 362-7. PMID 9657732 DOI: 10.1182/Blood.V92.2.362.414K38_362_367  0.527
1998 Rafii S, Mohle R, Shapiro F, Frey BM, Moore MA. Regulation of hematopoiesis by microvascular endothelium. Leukemia & Lymphoma. 27: 375-86. PMID 9477120 DOI: 10.3109/10428199709058305  0.516
1998 Möhle R, Salemi P, Moore MA, Rafii S. Expression of interleukin-5 by human bone marrow microvascular endothelial cells: implications for the regulation of eosinophilopoiesis in vivo. British Journal of Haematology. 99: 732-8. PMID 9432015 DOI: 10.1046/J.1365-2141.1997.4713279.X  0.314
1998 Frey BM, Hackett NR, Bergelson JM, Finberg R, Crystal RG, Moore MAS, Rafii S. High-efficiency gene transfer into ex vivo expanded human hematopoietic progenitors and precursor cells by adenovirus vectors. Blood. 91: 2781-2792. DOI: 10.1182/Blood.V91.8.2781.2781_2781_2792  0.415
1998 Möhle R, Bautz F, Rafii S, Moore MA, Brugger W, Kanz L. The Chemokine Receptor CXCR-4 Is Expressed on CD34+Hematopoietic Progenitors and Leukemic Cells and Mediates Transendothelial Migration Induced by Stromal Cell-Derived Factor-1 Blood. 91: 4523-4530. DOI: 10.1182/Blood.V91.12.4523.412K04_4523_4530  0.48
1998 Flore O, Hyjek E, Nikolovska S, Diana S, Rafii S, Cesarman E. CHARACTERIZATION OF KSHV/HHV-8 ACUTE INFECTION IN PRIMARY HUMAN BONE MARROW ENDOTHELIAL CELLS. Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology. 17: A28. DOI: 10.1097/00042560-199804010-00082  0.413
1997 Song W, Kong HL, Carpenter H, Torii H, Granstein R, Rafii S, Moore MA, Crystal RG. Dendritic cells genetically modified with an adenovirus vector encoding the cDNA for a model antigen induce protective and therapeutic antitumor immunity. The Journal of Experimental Medicine. 186: 1247-56. PMID 9334364 DOI: 10.1084/Jem.186.8.1247  0.339
1997 Möhle R, Green D, Moore MA, Nachman RL, Rafii S. Constitutive production and thrombin-induced release of vascular endothelial growth factor by human megakaryocytes and platelets. Proceedings of the National Academy of Sciences of the United States of America. 94: 663-8. PMID 9012841 DOI: 10.1073/Pnas.94.2.663  0.553
1997 Möhle R, Moore MA, Nachman RL, Rafii S. Transendothelial Migration of CD34+ and Mature Hematopoietic Cells: An In Vitro Study Using a Human Bone Marrow Endothelial Cell Line Blood. 89: 72-80. DOI: 10.1182/Blood.V89.1.72.72_72_80  0.469
1996 Shapiro F, Pytowski B, Rafii S, Witte L, Hicklin DJ, Yao TJ, Moore MAS. The Effects of Flk-2/flt3 Ligand as Compared with c-kit Ligand on Short-Term and Long-Term Proliferation of CD34+ Hematopoietic Progenitors Elicited from Human Fetal Liver, Umbilical Cord Blood, Bone Marrow, and Mobilized Peripheral Blood Journal of Hematotherapy. 5: 655-662. PMID 9117254 DOI: 10.1089/Scd.1.1996.5.655  0.345
1996 Candal FJ, Rafii S, Parker JT, Ades EW, Ferris B, Nachman RL, Kellar KL. BMEC-1: a human bone marrow microvascular endothelial cell line with primary cell characteristics. Microvascular Research. 52: 221-34. PMID 8954864 DOI: 10.1006/Mvre.1996.0060  0.479
1996 Ohwada A, Rafii S, Moore MAS, Crystal RG. In vivo adenovirus vector-mediated transfer of the human thrombopoietin cDNA maintains platelet levels during radiation-and chemotherapy- induced bone marrow suppression Blood. 88: 778-784. DOI: 10.1182/Blood.V88.3.778.778  0.315
1995 Rafii S, Shapiro F, Pettengell R, Ferris B, Nachman R, Moore M, Asch A. Human bone marrow microvascular endothelial cells support long-term proliferation and differentiation of myeloid and megakaryocytic progenitors Blood. 86: 3353-3363. DOI: 10.1182/Blood.V86.9.3353.Bloodjournal8693353  0.524
1994 Rafii S, Shapiro F, Rimarachin J, Nachman R, Ferris B, Weksler B, Moore M, Asch A. Isolation and characterization of human bone marrow microvascular endothelial cells: hematopoietic progenitor cell adhesion Blood. 84: 10-19. DOI: 10.1182/Blood.V84.1.10.10  0.486
1990 Young LH, Liu CC, Joag S, Rafii S, Young JD. How lymphocytes kill. Annual Review of Medicine. 41: 45-54. PMID 2184743 DOI: 10.1146/Annurev.Me.41.020190.000401  0.352
Show low-probability matches.