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Vince Cryns - Publications

Affiliations: 
Northwestern University, Evanston, IL 
Area:
Cell Biology, Molecular Biology
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35 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Etheridge T, Damodaran S, Schultz A, Richards KA, Gawdzik J, Yang B, Cryns V, Jarrard DF. Combination therapy with androgen deprivation for hormone sensitive prostate cancer: A new frontier. Asian Journal of Urology. 6: 57-64. PMID 30775249 DOI: 10.1016/J.Ajur.2018.09.001  0.319
2019 Strekalova E, Malin D, Rajanala H, Cryns VL. Preclinical Breast Cancer Models to Investigate Metabolic Priming by Methionine Restriction. Methods in Molecular Biology (Clifton, N.J.). 1866: 61-73. PMID 30725408 DOI: 10.1007/978-1-4939-8796-2_6  0.387
2017 Strekalova E, Malin D, Rajanala H, Cryns VL. Metformin sensitizes triple-negative breast cancer to proapoptotic TRAIL receptor agonists by suppressing XIAP expression. Breast Cancer Research and Treatment. 163: 435-447. PMID 28324269 DOI: 10.1007/s10549-017-4201-0  0.392
2016 Ugolkov A, Gaisina I, Zhang JS, Billadeau DD, White K, Kozikowski A, Jain S, Cristofanilli M, Giles F, O'Halloran T, Cryns VL, Mazar AP. GSK-3 inhibition overcomes chemoresistance in human breast cancer. Cancer Letters. PMID 27424289 DOI: 10.1016/J.Canlet.2016.07.006  0.349
2016 Malin D, Petrovic V, Strekalova E, Sharma B, Cryns VL. αB-crystallin: Portrait of a malignant chaperone as a cancer therapeutic target. Pharmacology & Therapeutics. PMID 26820756 DOI: 10.1016/j.pharmthera.2016.01.012  0.438
2015 Strekalova E, Malin D, Good DM, Cryns VL. Methionine Deprivation Induces a Targetable Vulnerability in Triple-Negative Breast Cancer Cells by Enhancing TRAIL Receptor-2 Expression. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 2780-91. PMID 25724522 DOI: 10.1158/1078-0432.CCR-14-2792  0.424
2013 Petrovic V, Malin D, Cryns VL. αB-crystallin promotes oncogenic transformation and inhibits caspase activation in cells primed for apoptosis by Rb inactivation. Breast Cancer Research and Treatment. 138: 415-25. PMID 23471649 DOI: 10.1007/s10549-013-2465-6  0.447
2011 Malin D, Chen F, Schiller C, Koblinski J, Cryns VL. Enhanced metastasis suppression by targeting TRAIL receptor 2 in a murine model of triple-negative breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 5005-15. PMID 21653692 DOI: 10.1158/1078-0432.CCR-11-0099  0.378
2011 Toft DJ, Cryns VL. Minireview: Basal-like breast cancer: from molecular profiles to targeted therapies. Molecular Endocrinology (Baltimore, Md.). 25: 199-211. PMID 20861225 DOI: 10.1210/Edrv.31.5.9988  0.359
2010 Oshita SE, Chen F, Kwan T, Yehiely F, Cryns VL. The small heat shock protein HspB2 is a novel anti-apoptotic protein that inhibits apical caspase activation in the extrinsic apoptotic pathway. Breast Cancer Research and Treatment. 124: 307-15. PMID 20087649 DOI: 10.1007/S10549-010-0735-0  0.699
2010 Evans JR, Bosman JD, Brown-Endres L, Yehiely F, Cryns VL. Induction of the small heat shock protein alphaB-crystallin by genotoxic stress is mediated by p53 and p73. Breast Cancer Research and Treatment. 122: 159-68. PMID 19777343 DOI: 10.1007/S10549-009-0542-7  0.725
2010 Bosman JD, Yehiely F, Evans JR, Cryns VL. Regulation of alphaB-crystallin gene expression by the transcription factor Ets1 in breast cancer. Breast Cancer Research and Treatment. 119: 63-70. PMID 19205872 DOI: 10.1007/S10549-009-0330-4  0.748
2008 Lu M, Strohecker A, Chen F, Kwan T, Bosman J, Jordan VC, Cryns VL. Aspirin sensitizes cancer cells to TRAIL-induced apoptosis by reducing survivin levels. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 3168-76. PMID 18483385 DOI: 10.1158/1078-0432.Ccr-07-4362  0.718
2008 Strohecker AM, Yehiely F, Chen F, Cryns VL. Caspase cleavage of HER-2 releases a Bad-like cell death effector. The Journal of Biological Chemistry. 283: 18269-82. PMID 18420586 DOI: 10.1074/Jbc.M802156200  0.763
2008 Ivanov O, Chen F, Wiley EL, Keswani A, Diaz LK, Memmel HC, Rademaker A, Gradishar WJ, Morrow M, Khan SA, Cryns VL. alphaB-crystallin is a novel predictor of resistance to neoadjuvant chemotherapy in breast cancer. Breast Cancer Research and Treatment. 111: 411-7. PMID 17968656 DOI: 10.1007/s10549-007-9796-0  0.346
2007 Werner ME, Chen F, Moyano JV, Yehiely F, Jones JC, Cryns VL. Caspase proteolysis of the integrin beta4 subunit disrupts hemidesmosome assembly, promotes apoptosis, and inhibits cell migration. The Journal of Biological Chemistry. 282: 5560-9. PMID 17178732 DOI: 10.1074/jbc.M603669200  0.378
2007 Dusek RL, Godsel LM, Chen F, Strohecker AM, Getsios S, Harmon R, Müller EJ, Caldelari R, Cryns VL, Green KJ. Plakoglobin deficiency protects keratinocytes from apoptosis Journal of Investigative Dermatology. 127: 792-801. PMID 17110936 DOI: 10.1038/Sj.Jid.5700615  0.739
2006 Yehiely F, Moyano JV, Evans JR, Nielsen TO, Cryns VL. Deconstructing the molecular portrait of basal-like breast cancer. Trends in Molecular Medicine. 12: 537-44. PMID 17011236 DOI: 10.1016/j.molmed.2006.09.004  0.329
2006 Moyano JV, Evans JR, Chen F, Lu M, Werner ME, Yehiely F, Diaz LK, Turbin D, Karaca G, Wiley E, Nielsen TO, Perou CM, Cryns VL. AlphaB-crystallin is a novel oncoprotein that predicts poor clinical outcome in breast cancer. The Journal of Clinical Investigation. 116: 261-70. PMID 16395408 DOI: 10.1172/Jci25888  0.41
2006 Dusek RL, Getsios S, Chen F, Park JK, Amargo EV, Cryns VL, Green KJ. The differentiation-dependent desmosomal cadherin desmoglein 1 is a novel caspase-3 target that regulates apoptosis in keratinocytes Journal of Biological Chemistry. 281: 3614-3624. PMID 16286477 DOI: 10.1074/Jbc.M508258200  0.469
2005 Hyer ML, Croxton R, Krajewska M, Krajewski S, Kress CL, Lu M, Suh N, Sporn MB, Cryns VL, Zapata JM, Reed JC. Synthetic triterpenoids cooperate with tumor necrosis factor-related apoptosis-inducing ligand to induce apoptosis of breast cancer cells. Cancer Research. 65: 4799-808. PMID 15930300 DOI: 10.1158/0008-5472.Can-04-3319  0.608
2005 Kamradt MC, Lu M, Werner ME, Kwan T, Chen F, Strohecker A, Oshita S, Wilkinson JC, Yu C, Oliver PG, Duckett CS, Buchsbaum DJ, LoBuglio AF, Jordan VC, Cryns VL. The small heat shock protein αB-crystallin is a novel inhibitor of TRAIL-induced apoptosis that suppresses the activation of caspase-3 Journal of Biological Chemistry. 280: 11059-11066. PMID 15653686 DOI: 10.1074/Jbc.M413382200  0.639
2005 Ebert AD, Chen F, He X, Cryns VL, Bohn MC. A tetracycline-regulated adenovirus encoding dominant-negative caspase-9 is regulated in rat brain and protects against neurotoxin-induced cell death in vitro, but not in vivo. Experimental Neurology. 191: S80-94. PMID 15629764 DOI: 10.1016/J.Expneurol.2004.08.024  0.319
2005 Lu M, Kwan T, Yu C, Chen F, Freedman B, Schafer JM, Lee EJ, Jameson JL, Jordan VC, Cryns VL. Peroxisome proliferator-activated receptor gamma agonists promote TRAIL-induced apoptosis by reducing survivin levels via cyclin D3 repression and cell cycle arrest. The Journal of Biological Chemistry. 280: 6742-51. PMID 15569667 DOI: 10.1074/jbc.M411519200  0.56
2004 Chen F, Arseven OK, Cryns VL. Proteolysis of the mismatch repair protein MLH1 by caspase-3 promotes DNA damage-induced apoptosis. The Journal of Biological Chemistry. 279: 27542-8. PMID 15087450 DOI: 10.1074/jbc.M400971200  0.504
2003 Chen F, Chang R, Trivedi M, Capetanaki Y, Cryns VL. Caspase proteolysis of desmin produces a dominant-negative inhibitor of intermediate filaments and promotes apoptosis. The Journal of Biological Chemistry. 278: 6848-53. PMID 12477713 DOI: 10.1074/jbc.M212021200  0.49
2002 Kamradt MC, Chen F, Sam S, Cryns VL. The small heat shock protein alpha B-crystallin negatively regulates apoptosis during myogenic differentiation by inhibiting caspase-3 activation. The Journal of Biological Chemistry. 277: 38731-6. PMID 12140279 DOI: 10.1074/jbc.M201770200  0.515
2002 Chen F, Kamradt M, Mulcahy M, Byun Y, Xu H, McKay MJ, Cryns VL. Caspase proteolysis of the cohesin component RAD21 promotes apoptosis. The Journal of Biological Chemistry. 277: 16775-81. PMID 11875078 DOI: 10.1074/jbc.M201322200  0.448
2001 Byun Y, Chen F, Chang R, Trivedi M, Green KJ, Cryns VL. Caspase cleavage of vimentin disrupts intermediate filaments and promotes apoptosis Cell Death and Differentiation. 8: 443-450. PMID 11423904 DOI: 10.1038/Sj.Cdd.4400840  0.455
2001 Kamradt MC, Chen F, Cryns VL. The small heat shock protein alpha B-crystallin negatively regulates cytochrome c- and caspase-8-dependent activation of caspase-3 by inhibiting its autoproteolytic maturation. The Journal of Biological Chemistry. 276: 16059-63. PMID 11274139 DOI: 10.1074/jbc.C100107200  0.51
1999 Bialik S, Cryns VL, Drincic A, Miyata S, Wollowick AL, Srinivasan A, Kitsis RN. The mitochondrial apoptotic pathway is activated by serum and glucose deprivation in cardiac myocytes Circulation Research. 85: 403-414. PMID 10473670 DOI: 10.1161/01.Res.85.5.403  0.419
1999 Holly TA, Drincic A, Byun Y, Nakamura S, Harris K, Klocke FJ, Cryns VL. Caspase inhibition reduces myocyte cell death induced by myocardial ischemia and reperfusion in vivo. Journal of Molecular and Cellular Cardiology. 31: 1709-15. PMID 10471354 DOI: 10.1006/jmcc.1999.1006  0.338
1997 Cryns VL, Byun Y, Rana A, Mellor H, Lustig KD, Ghanem L, Parker PJ, Kirschner MW, Yuan J. Specific proteolysis of the kinase protein kinase C-related kinase 2 by caspase-3 during apoptosis. Identification by a novel, small pool expression cloning strategy. The Journal of Biological Chemistry. 272: 29449-53. PMID 9368003 DOI: 10.1074/Jbc.272.47.29449  0.436
1997 Li H, Bergeron L, Cryns V, Pasternack MS, Zhu H, Shi L, Greenberg A, Yuan J. Activation of caspase-2 in apoptosis. The Journal of Biological Chemistry. 272: 21010-7. PMID 9261102 DOI: 10.1074/Jbc.272.34.21010  0.406
1996 Cryns VL, Bergeron L, Zhu H, Li H, Yuan J. Specific cleavage of alpha-fodrin during Fas- and tumor necrosis factor-induced apoptosis is mediated by an interleukin-1beta-converting enzyme/Ced-3 protease distinct from the poly(ADP-ribose) polymerase protease. The Journal of Biological Chemistry. 271: 31277-82. PMID 8940132 DOI: 10.1074/Jbc.271.49.31277  0.383
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