Suzanne D. Conzen - Publications

Affiliations: 
University of Chicago, Chicago, IL 
Area:
Cell Biology, Molecular Biology, Pathology

107 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Bennett L, Jaiswal PK, Harkless RV, Long TM, Gao N, Vandenburg B, Selman P, Durdana I, Lastra RR, Vander Griend D, Adelaiye-Ogala R, Szmulewitz RZ, Conzen SD. Glucocorticoid receptor (GR) activation is associated with increased cAMP/PKA signaling in castrate-resistant prostate cancer. Molecular Cancer Therapeutics. PMID 38030378 DOI: 10.1158/1535-7163.MCT-22-0479  0.313
2023 Porter BA, Frerich C, Lainé M, Clark AB, Durdana I, Lee J, Taya M, Sahoo S, Greene GL, Bennett L, Conzen SD. Glucocorticoid Receptor Activation in Lobular Breast Cancer Is Associated with Reduced Cell Proliferation and Promotion of Metastases. Cancers. 15. PMID 37835373 DOI: 10.3390/cancers15194679  0.437
2020 Blatt EB, Kopplin N, Kumar S, Mu P, Conzen SD, Raj GV. Overcoming oncogene addiction in breast and prostate cancers: a comparative mechanistic overview. Endocrine-Related Cancer. PMID 33263560 DOI: 10.1530/ERC-20-0272  0.327
2020 Mustafi D, Valek R, Fitch M, Werner V, Fan X, Markiewicz E, Fernandez S, Zamora M, Mueller J, Olopade OI, Conzen SD, Brady MJ, Karczmar GS. Magnetic resonance angiography reveals increased arterial blood supply and tumorigenesis following high fat feeding in a mouse model of triple-negative breast cancer. Nmr in Biomedicine. 33: e4363. PMID 32881124 DOI: 10.1002/Nbm.4363  0.401
2019 Narayan V, Harrison M, Cheng H, Kenfield S, Aggarwal R, Kwon D, McKay R, Hauger R, Hart N, Conzen S, Borno H, Jim H, Dicker A, Dorff T, Moslehi J, et al. Improving research for prostate cancer survivorship: A statement from the Survivorship Research in Prostate Cancer (SuRECaP) working group. Urologic Oncology. PMID 31734020 DOI: 10.1016/J.Urolonc.2019.10.006  0.308
2019 Tonsing-Carter E, Hernandez KM, Kim CR, Harkless RV, Oh A, Bowie KR, West-Szymanski DC, Betancourt-Ponce MA, Green BD, Lastra RR, Fleming GF, Chandarlapaty S, Conzen SD. Glucocorticoid receptor modulation decreases ER-positive breast cancer cell proliferation and suppresses wild-type and mutant ER chromatin association. Breast Cancer Research : Bcr. 21: 82. PMID 31340854 DOI: 10.1186/S13058-019-1164-6  0.474
2019 Yeh AC, Li H, Zhu Y, Zhang J, Khramtsova G, Drukker K, Edwards A, McGregor S, Yoshimatsu T, Zheng Y, Niu Q, Abe H, Mueller J, Conzen S, Ji Y, et al. Radiogenomics of breast cancer using dynamic contrast enhanced MRI and gene expression profiling. Cancer Imaging : the Official Publication of the International Cancer Imaging Society. 19: 48. PMID 31307537 DOI: 10.1186/S40644-019-0233-5  0.409
2019 Mustafi D, Leinroth A, Fan X, Markiewicz E, Zamora M, Mueller J, Conzen SD, Karczmar GS. Magnetic Resonance Angiography Shows Increased Arterial Blood Supply Associated with Murine Mammary Cancer. International Journal of Biomedical Imaging. 2019: 5987425. PMID 30792738 DOI: 10.1155/2019/5987425  0.371
2019 Veneris JT, Huang L, Churpek JE, Conzen SD, Fleming GF. Glucocorticoid receptor expression is associated with inferior overall survival independent of BRCA mutation status in ovarian cancer. International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society. PMID 30683758 DOI: 10.1136/Ijgc-2018-000101  0.458
2019 Veneris JT, Hou X, Weroha SJ, Heinzen EP, Maurer MJ, Oberg AL, Conzen SD, Fleming GF. Selective and nonselective GR antagonists in combination with chemotherapy in ovarian cancer PDX models. Journal of Clinical Oncology. 37: e17039-e17039. DOI: 10.1200/Jco.2019.37.15_Suppl.E17039  0.395
2019 Steiner M, Veneris JT, Lastra R, Weroha SJ, Hou X, Maurer MJ, Heinzen EP, Oberg AL, Fleming GF, Conzen SD. Glucocorticoid receptor expression in Müllerian carcinosarcomas. Journal of Clinical Oncology. 37: e17038-e17038. DOI: 10.1200/Jco.2019.37.15_Suppl.E17038  0.411
2019 Dolcen DN, Szymanski DW, Panchamukhi A, Wang X, Sweis RF, Nanda R, Conzen S. Abstract 2812: Triple-negative breast cancer cell-intrinsic glucocorticoid receptor activity and modulation of the immune microenvironment Cancer Research. 79: 2812-2812. DOI: 10.1158/1538-7445.Am2019-2812  0.458
2019 Bueter E, Hosfield D, McAuley E, Selman P, Greene G, Conzen SD, Szmulewitz RZ. Abstract 1016: The androgen receptor splice variant AR-V7 associates with the glucocorticoid receptor following androgen blockade Cancer Research. 79: 1016-1016. DOI: 10.1158/1538-7445.Am2019-1016  0.373
2019 Veneris JLT, Panchamukhi A, Pearson AT, Fleming GF, Conzen SD. Discovery of transcriptional signature of glucocorticoid receptor (GR) activation in ovarian cancer using selective GR modulators Gynecologic Oncology. 154: 57. DOI: 10.1016/J.Ygyno.2019.04.137  0.392
2018 Johnson MB, Hoffmann JN, You HM, Lastra RR, Fernandez S, Strober JW, Allaw AB, Brady MJ, Conzen SD, McClintock MK. Psychosocial Stress Exposure Disrupts Mammary Gland Development. Journal of Mammary Gland Biology and Neoplasia. PMID 29687293 DOI: 10.1007/S10911-018-9392-4  0.394
2018 West DC, Kocherginsky M, Tonsing-Carter EY, Dolcen DN, Hosfield DJ, Lastra RR, Sinnwell JP, Thompson KJ, Bowie KR, Harkless RV, Skor MN, Pierce CF, Styke SC, Kim CR, de Wet L, ... ... Conzen SD, et al. Discovery of a glucocorticoid receptor (GR) activity signature using selective GR antagonism in ER-negative breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 29636357 DOI: 10.1158/1078-0432.Ccr-17-2793  0.68
2018 He D, Mustafi D, Fan X, Fernandez S, Markiewicz E, Zamora M, Mueller J, Sachleben JR, Brady MJ, Conzen SD, Karczmar GS. Magnetic resonance spectroscopy detects differential lipid composition in mammary glands on low fat, high animal fat versus high fructose diets. Plos One. 13: e0190929. PMID 29324859 DOI: 10.1371/Journal.Pone.0190929  0.33
2018 Johnson MB, Hoffmann JN, You HM, Allaw AB, Strober JW, Brady MJ, McClintock MK, Conzen SD. Abstract B53: Psychosocial stress exposure results in inhibition of mammary gland development and increased mammary stem cells in a rat model of breast cancer Cancer Epidemiology, Biomarkers & Prevention. 27. DOI: 10.1158/1538-7755.Disp17-B53  0.472
2018 Long TM, Tonsing-Carter EY, Chan W, Griend DV, Conzen SD, Szmulewitz RZ. Abstract 944: Glucocorticoid receptor (GR)-mediated activation of cyclic-adenosine monophosphate (cAMP) pathway gene expression following androgen receptor (AR) antagonism of prostate cancer Cancer Research. 78: 944-944. DOI: 10.1158/1538-7445.Am2018-944  0.44
2017 Press DJ, Ibraheem A, Dolan ME, Goss KH, Conzen S, Huo D. Racial disparities in omission of oncotype DX but no racial disparities in chemotherapy receipt following completed oncotype DX test results. Breast Cancer Research and Treatment. PMID 29181717 DOI: 10.1007/S10549-017-4587-8  0.371
2017 Tangen IL, Veneris JT, Halle MK, Werner HM, Trovik J, Akslen LA, Salvesen HB, Conzen SD, Fleming GF, Krakstad C. Expression of glucocorticoid receptor is associated with aggressive primary endometrial cancer and increases from primary to metastatic lesions. Gynecologic Oncology. PMID 28927900 DOI: 10.1016/J.Ygyno.2017.09.013  0.432
2017 Mustafi D, Fernandez S, Markiewicz E, Fan X, Zamora M, Mueller J, Brady MJ, Conzen SD, Karczmar GS. MRI reveals increased tumorigenesis following high fat feeding in a mouse model of triple-negative breast cancer. Nmr in Biomedicine. PMID 28661075 DOI: 10.1002/Nbm.3758  0.413
2017 Veneris JT, Darcy KM, Mhawech-Fauceglia P, Tian C, Lengyel E, Lastra RR, Pejovic T, Conzen SD, Fleming GF. High glucocorticoid receptor expression predicts short progression-free survival in ovarian cancer. Gynecologic Oncology. PMID 28456378 DOI: 10.1016/J.Ygyno.2017.04.012  0.439
2017 Kach J, Long TM, Selman P, Tonsing-Carter EY, Bacalao MA, Lastra RR, de Wet L, Comiskey S, Gillard M, VanOpstall C, West DC, Chan WC, Vander Griend D, Conzen SD, Szmulewitz RZ. Selective glucocorticoid receptor modulators (SGRMs) delay castrate-resistant prostate cancer growth. Molecular Cancer Therapeutics. PMID 28428441 DOI: 10.1158/1535-7163.Mct-16-0923  0.628
2017 Markiewicz E, Fan X, Mustafi D, Zamora M, Conzen SD, Karczmar GS. MRI ductography of contrast agent distribution and leakage in normal mouse mammary ducts and ducts with in situ cancer. Magnetic Resonance Imaging. PMID 28366759 DOI: 10.1016/J.Mri.2017.03.009  0.374
2017 Stringer EM, Saha P, Swoboda A, Kocherginsky M, Baker G, Olberkyte S, Owusu N, Dyer B, Olalde L, Olszewski E, Hahn OM, Hoffman PC, Phillips BE, Suh GK, Conzen SD, et al. A phase I trial of mifepristone (M), carboplatin (C), and gemcitabine (G) in advanced breast and ovarian cancer. Journal of Clinical Oncology. 35: 1083-1083. DOI: 10.1200/Jco.2017.35.15_Suppl.1083  0.307
2017 Han H, Wilks S, Paplomata E, Modiano, Becerra C, Braiteh F, Spira A, Pluard T, Richards D, Conzen S, Baker G, Fishman R, Marcantonio A, O'Shaughnessy J, Nanda R. Abstract P6-12-15: Efficacy results of a phase 1/2 study of glucocorticoid receptor (GR) antagonist mifepristone (MIFE) in combination with eribulin in GR-positive triple-negative breast cancer (TNBC) Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-P6-12-15  0.429
2017 Tonsing-Carter E, Bowie K, West D, Harkless R, Hernandez K, Conzen S. Abstract P3-05-09: Glucocorticoid receptor modulation affects ER+ breast cancer cell proliferation Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-P3-05-09  0.653
2017 Veneris J, Huang L, Churpek J, Conzen S, Fleming G. Relationship of tumor glucocorticoid receptor expression with overall survival in ovarian cancer TCGA data Gynecologic Oncology. 145: 33. DOI: 10.1016/J.Ygyno.2017.03.087  0.427
2016 Li H, Zhu Y, Burnside ES, Huang E, Drukker K, Hoadley KA, Fan C, Conzen SD, Zuley M, Net JM, Sutton E, Whitman GJ, Morris E, Perou CM, Ji Y, et al. Quantitative MRI radiomics in the prediction of molecular classifications of breast cancer subtypes in the TCGA/TCIA data set. Npj Breast Cancer. 2. PMID 27853751 DOI: 10.1038/npjbcancer.2016.12  0.345
2016 Nanda R, Stringer-Reasor EM, Saha P, Kocherginsky M, Gibson J, Libao B, Hoffman PC, Obeid E, Merkel DE, Khramtsova G, Skor M, Krausz T, Cohen RN, Ratain MJ, Fleming GF, ... Conzen SD, et al. A randomized phase I trial of nanoparticle albumin-bound paclitaxel with or without mifepristone for advanced breast cancer. Springerplus. 5: 947. PMID 27386391 DOI: 10.1186/S40064-016-2457-1  0.456
2016 Li H, Zhu Y, Burnside ES, Drukker K, Hoadley KA, Fan C, Conzen SD, Whitman GJ, Sutton EJ, Net JM, Ganott M, Huang E, Morris EA, Perou CM, Ji Y, et al. MR Imaging Radiomics Signatures for Predicting the Risk of Breast Cancer Recurrence as Given by Research Versions of MammaPrint, Oncotype DX, and PAM50 Gene Assays. Radiology. 152110. PMID 27144536 DOI: 10.1148/Radiol.2016152110  0.447
2016 West DC, Pan D, Tonsing-Carter EY, Hernandez KM, Pierce CF, Styke SC, Bowie KR, Garcia TI, Kocherginsky M, Conzen SD. GR and ER co-activation alters the expression of differentiation genes and associates with improved ER+ breast cancer outcome. Molecular Cancer Research : McR. PMID 27141101 DOI: 10.1158/1541-7786.Mcr-15-0433  0.651
2016 Volden PA, Skor MN, Johnson MB, Singh P, Patel FN, McClintock MK, Brady MJ, Conzen SD. Mammary Adipose Tissue-derived Lysophospholipids Promote Estrogen Receptor-negative Mammary Epithelial Cell Proliferation. Cancer Prevention Research (Philadelphia, Pa.). PMID 26862086 DOI: 10.1158/1940-6207.Capr-15-0107  0.793
2016 Agyeman AS, Jun WJ, Proia DA, Kim CR, Skor MN, Kocherginsky M, Conzen SD. Hsp90 Inhibition Results in Glucocorticoid Receptor Degradation in Association with Increased Sensitivity to Paclitaxel in Triple-Negative Breast Cancer. Hormones & Cancer. PMID 26858237 DOI: 10.1007/S12672-016-0251-8  0.481
2016 Wilks S, Modiano MR, Spira AI, Becerra C, Han HS, Braiteh FS, Paplomata E, Pluard TJ, Richards DA, O'Shaughnessy J, Walling J, Fishman RS, Baker G, Conzen SD, Nanda R. Phase 1/2 study of glucocorticoid receptor (GR) antagonist mifepristone (MIFE) in combination with eribulin (E) in advanced solid tumors, with dose expansion in patients with GR-positive (GR+) triple-negative breast cancer (TNBC). Journal of Clinical Oncology. 34: e12550-e12550. DOI: 10.1200/Jco.2016.34.15_Suppl.E12550  0.407
2016 Veneris JT, Darcy KM, Mhawech-Fauceglia P, Conzen SD, Fleming GF. Glucocorticoid receptor expression and survival in ovarian cancer. Journal of Clinical Oncology. 34: 5545-5545. DOI: 10.1200/Jco.2016.34.15_Suppl.5545  0.403
2016 Johnson M, Hoffmann JN, You H, Kunze K, Fernandez S, Brady M, McClintock M, Conzen S. Abstract A63: The impact of psychosocial stress on pubertal mammary gland development in a rat model of spontaneous breast cancer Cancer Epidemiology, Biomarkers & Prevention. 25. DOI: 10.1158/1538-7755.Disp15-A63  0.458
2016 West D, Hosfield D, Mayne C, Skor M, Styke S, Pierce C, Kocherginsky M, Hunt H, Fleming G, Szmulewitz R, Tajkhorshid E, Greene G, Conzen S. Abstract PD3-02: Second-generation selective glucocorticoid receptor modulators in triple-negative breast cancer Cancer Research. 76. DOI: 10.1158/1538-7445.Sabcs15-Pd3-02  0.682
2016 Wilks S, Modiano M, Spira A, Becerra C, Walling J, Nguyen D, Baker G, Conzen S, Nanda R. Abstract P6-13-21: Phase 1 study of GR antagonist mifepristone (M) in combination with eribulin (E) in advanced solid tumors, with dose expansion in patients (pts) with GR-positive triple-negative breast cancer (TNBC) Cancer Research. 76. DOI: 10.1158/1538-7445.Sabcs15-P6-13-21  0.364
2016 Saha P, Turk A, Lurain K, Baker G, Conzen S, Nanda R. Abstract P3-07-24: The role of glucocorticoid receptor (GR) expression in predicting pathological complete response (pCR) to neoadjuvant chemotherapy in triple-negative breast cancer (TNBC) Cancer Research. 76. DOI: 10.1158/1538-7445.Sabcs15-P3-07-24  0.486
2016 Kach J, Selman P, West DC, Griend DJV, Conzen SD, Szmulewitz RZ. Abstract 334: Novel selective glucocorticoid receptor modulators (SGRMs) in castration-resistant prostate cancer Cancer Research. 76: 334-334. DOI: 10.1158/1538-7445.Am2016-334  0.442
2016 Agyeman AS, Jun WJ, Conzen SD. Abstract 3100: Hsp90 inhibition results in GR, AR and JAK protein degradation, decreased triple-negative breast cancer proliferation and increased paclitaxel sensitivity Cancer Research. 76: 3100-3100. DOI: 10.1158/1538-7445.Am2016-3100  0.464
2015 Burnside ES, Drukker K, Li H, Bonaccio E, Zuley M, Ganott M, Net JM, Sutton EJ, Brandt KR, Whitman GJ, Conzen SD, Lan L, Ji Y, Zhu Y, Jaffe CC, et al. Using computer-extracted image phenotypes from tumors on breast magnetic resonance imaging to predict breast cancer pathologic stage. Cancer. PMID 26619259 DOI: 10.1002/Cncr.29791  0.378
2015 Singh P, Brock CO, Volden PA, Hernandez K, Skor M, Kocherginsky M, Park JE, Brady MJ, Conzen SD. Glucocorticoid receptor ChIP-sequencing of subcutaneous fat reveals modulation of inflammatory pathways. Obesity (Silver Spring, Md.). PMID 26408078 DOI: 10.1002/Oby.21251  0.735
2015 Kach J, Conzen SD, Szmulewitz RZ. Targeting the glucocorticoid receptor in breast and prostate cancers. Science Translational Medicine. 7: 305ps19. PMID 26378243 DOI: 10.1126/Scitranslmed.Aac7531  0.456
2015 Fan X, Macleod K, Mustafi D, Conzen SD, Markiewicz E, Zamora M, Vosicky J, Mueller J, Karczmar GS. Correlation of In Vivo and Ex Vivo ADC and T2 of In Situ and Invasive Murine Mammary Cancers. Plos One. 10: e0129212. PMID 26208092 DOI: 10.1371/Journal.Pone.0129212  0.364
2015 Mustafi D, Zamora M, Fan X, Markiewicz E, Mueller J, Conzen SD, Karczmar GS. MRI accurately identifies early murine mammary cancers and reliably differentiates between in situ and invasive cancer: correlation of MRI with histology. Nmr in Biomedicine. 28: 1078-86. PMID 26152557 DOI: 10.1002/Nbm.3348  0.417
2015 Stringer-Reasor EM, Baker GM, Skor MN, Kocherginsky M, Lengyel E, Fleming GF, Conzen SD. Glucocorticoid receptor activation inhibits chemotherapy-induced cell death in high-grade serous ovarian carcinoma. Gynecologic Oncology. 138: 656-62. PMID 26115975 DOI: 10.1016/J.Ygyno.2015.06.033  0.371
2015 Nanda R, Wilks S, Modiano MR, Spira AI, Becerra C, Walling J, Nguyen D, Baker G, Conzen SD. Mifepristone (MIFE), a glucocorticoid receptor (GR) antagonist, in combination with eribulin (E) in advanced solid tumors: A phase 1 study with dose expansion in patients (pts) with triple-negative breast cancer (TNBC). Journal of Clinical Oncology. 33: e12070-e12070. DOI: 10.1200/Jco.2015.33.15_Suppl.E12070  0.421
2015 West DC, Pierce CF, Pan D, Hernandez K, Kocherginsky M, Conzen SD. Abstract 4675: GR activation modifies ER transcriptional activity and results in decreased estrogen-mediated breast cancer cell proliferation Cancer Research. 75: 4675-4675. DOI: 10.1158/1538-7445.Am2015-4675  0.469
2014 Fan X, Mustafi D, Markiewicz E, Zamora M, Vosicky J, Leinroth A, Mueller J, Macleod K, Conzen SD, Karczmar GS. Mammary cancer initiation and progression studied with magnetic resonance imaging. Breast Cancer Research : Bcr. 16: 495. PMID 25510596 DOI: 10.1186/S13058-014-0495-6  0.36
2014 Maranville JC, Nanda R, Fleming GF, Skor MN, Di Rienzo A, Conzen SD. Gene expression of peripheral blood cells reveals pathways downstream of glucocorticoid receptor antagonism and nab-paclitaxel treatment. Pharmacogenetics and Genomics. 24: 451-8. PMID 25000515 DOI: 10.1097/Fpc.0000000000000077  0.378
2014 Sachleben JR, Yi R, Volden PA, Conzen SD. Aliphatic chain length by isotropic mixing (ALCHIM): determining composition of complex lipid samples by ¹H NMR spectroscopy. Journal of Biomolecular Nmr. 59: 161-73. PMID 24831341 DOI: 10.1007/S10858-014-9836-0  0.705
2014 Isikbay M, Otto K, Kregel S, Kach J, Cai Y, Vander Griend DJ, Conzen SD, Szmulewitz RZ. Glucocorticoid receptor activity contributes to resistance to androgen-targeted therapy in prostate cancer. Hormones & Cancer. 5: 72-89. PMID 24615402 DOI: 10.1007/S12672-014-0173-2  0.412
2013 Brickley DR, Agyeman AS, Kopp RF, Hall BA, Harbeck MC, Belova L, Volden PA, Wu W, Roe MW, Conzen SD. Serum- and glucocorticoid-induced protein kinase 1 (SGK1) is regulated by store-operated Ca2+ entry and mediates cytoprotection against necrotic cell death. The Journal of Biological Chemistry. 288: 32708-19. PMID 24043625 DOI: 10.1074/Jbc.M113.507210  0.729
2013 Skor MN, Wonder EL, Kocherginsky M, Goyal A, Hall BA, Cai Y, Conzen SD. Glucocorticoid receptor antagonism as a novel therapy for triple-negative breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 6163-72. PMID 24016618 DOI: 10.1158/1078-0432.Ccr-12-3826  0.496
2013 Obeid EI, Conzen SD. The role of adrenergic signaling in breast cancer biology. Cancer Biomarkers : Section a of Disease Markers. 13: 161-9. PMID 23912488 DOI: 10.3233/Cbm-130347  0.49
2013 Volden PA, Wonder EL, Skor MN, Carmean CM, Patel FN, Ye H, Kocherginsky M, McClintock MK, Brady MJ, Conzen SD. Chronic social isolation is associated with metabolic gene expression changes specific to mammary adipose tissue. Cancer Prevention Research (Philadelphia, Pa.). 6: 634-45. PMID 23780289 DOI: 10.1158/1940-6207.Capr-12-0458  0.789
2013 Makinen MW, Bamba R, Ikejimba L, Wietholt C, Chen CT, Conzen SD. The vanadyl chelate bis(acetylacetonato)oxovanadium(IV) increases the fractional uptake of 2-(fluorine-18)-2-deoxy-D-glucose by cultured human breast carcinoma cells. Dalton Transactions (Cambridge, England : 2003). 42: 11862-7. PMID 23644715 DOI: 10.1039/C3Dt50549A  0.41
2013 Volden PA, Conzen SD. The influence of glucocorticoid signaling on tumor progression. Brain, Behavior, and Immunity. 30: S26-31. PMID 23164950 DOI: 10.1016/J.Bbi.2012.10.022  0.789
2013 Stringer EM, Skor MN, Fleming GF, Conzen SD. The role of the glucocorticoid receptor (GR) in inhibiting chemotherapy-induced apoptosis in high-grade serous ovarian carcinoma (HGS-OvCa). Journal of Clinical Oncology. 31: 11101-11101. DOI: 10.1200/Jco.2013.31.15_Suppl.11101  0.475
2013 Volden PA, Wonder E, Skor M, Patel F, McClintock M, Brady M, Conzen S. Abstract 1354: Chronic social stress in a mouse model of triple-negative breast cancer is associated with oncogenic changes in mammary fat. Cancer Research. 73: 1354-1354. DOI: 10.1158/1538-7445.Am2013-1354  0.798
2013 Stringer EM, Skor MN, Zhao L, Gwin K, Lengyel E, Fleming GF, Conzen SD. Abstract B32: The role of the glucocorticoid receptor (GR) in inhibiting chemotherapy-induced apoptosis in high-grade serous ovarian carcinoma (HGS-OvCa) Clinical Cancer Research. 19. DOI: 10.1158/1078-0432.Ovca13-B32  0.475
2013 Agyeman A, Jun W, Proia D, Lee N, Skor M, Conzen S. Abstract P4-16-05: Hsp90 inhibition potentiates chemotherapy effectiveness in triple negative breast cancer: Role of glucocorticoid receptor signaling Cancer Research. 73. DOI: 10.1158/0008-5472.Sabcs13-P4-16-05  0.492
2013 Nanda R, Chennamaneni P, Gibson J, Koetter K, Libao B, Skor M, Maranville J, Hoffman P, Obeid E, DiRienzo A, Fleming G, Conzen S. Abstract P2-16-21: A randomized phase I trial of nanoparticle albumin bound paclitaxel (nab-paclitaxel, Abraxane®) with or without mifepristone for advanced breast cancer Cancer Research. 73. DOI: 10.1158/0008-5472.Sabcs13-P2-16-21  0.4
2012 Hall BA, Kim TY, Skor MN, Conzen SD. Serum and glucocorticoid-regulated kinase 1 (SGK1) activation in breast cancer: requirement for mTORC1 activity associates with ER-alpha expression. Breast Cancer Research and Treatment. 135: 469-79. PMID 22842983 DOI: 10.1007/S10549-012-2161-Y  0.48
2012 Hipp E, Fan X, Jansen SA, Markiewicz EJ, Vosicky J, Newstead GM, Conzen SD, Krausz T, Karczmar GS. T(2)∗ relaxation times of intraductal murine mammary cancer, invasive mammary cancer, and normal mammary gland. Medical Physics. 39: 1309-13. PMID 22380363 DOI: 10.1118/1.3684950  0.414
2012 Fleming GF, Ma CX, Huo D, Sattar H, Tretiakova M, Lin L, Hahn OM, Olopade FO, Nanda R, Hoffman PC, Naughton MJ, Pluard T, Conzen SD, Ellis MJ. Phase II trial of temsirolimus in patients with metastatic breast cancer. Breast Cancer Research and Treatment. 136: 355-63. PMID 22245973 DOI: 10.1007/S10549-011-1910-7  0.419
2012 Szmulewitz RZ, Chung E, Al-Ahmadie H, Daniel S, Kocherginsky M, Razmaria A, Zagaja GP, Brendler CB, Stadler WM, Conzen SD. Serum/glucocorticoid-regulated kinase 1 expression in primary human prostate cancers. The Prostate. 72: 157-64. PMID 21563193 DOI: 10.1002/Pros.21416  0.391
2012 Conzen S. Abstract PL01-04: Stress and the social environment: Impact on cancer risk Cancer Prevention Research. 5: PL01-04-PL01-04. DOI: 10.1158/1940-6207.Prev-12-Pl01-04  0.546
2012 Volden PA, Wonder EL, Skor MN, Carmean CM, Ye H, Kocherginsky M, McClintock MK, Brady MJ, Conzen SD. Abstract 4116: Mammary adipocyte-specific metabolic alterations are associated with paracrine effects on mammary tumorigenesis Cancer Research. 72: 4116-4116. DOI: 10.1158/1538-7445.Am2012-4116  0.791
2012 Otto K, Griend DV, Conzen S, Szmulewitz R. Abstract 148: Glucocorticoid receptor-mediated cell survival following androgen receptor blockade in castrate-resistant prostate cancer Cancer Research. 72: 148-148. DOI: 10.1158/1538-7445.Am2012-148  0.413
2011 Pan D, Kocherginsky M, Conzen SD. Activation of the glucocorticoid receptor is associated with poor prognosis in estrogen receptor-negative breast cancer. Cancer Research. 71: 6360-70. PMID 21868756 DOI: 10.1158/0008-5472.Can-11-0362  0.537
2011 Melhem-Bertrandt A, Chavez-Macgregor M, Lei X, Brown EN, Lee RT, Meric-Bernstam F, Sood AK, Conzen SD, Hortobagyi GN, Gonzalez-Angulo AM. Beta-blocker use is associated with improved relapse-free survival in patients with triple-negative breast cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 2645-52. PMID 21632501 DOI: 10.1200/Jco.2010.33.4441  0.373
2011 Jansen SA, Conzen SD, Fan X, Markiewicz E, Krausz T, Newstead GM, Karczmar GS. In vivo MRI of early stage mammary cancers and the normal mouse mammary gland. Nmr in Biomedicine. 24: 880-7. PMID 21264977 DOI: 10.1002/Nbm.1643  0.381
2011 Conzen SD, Volden P, Brady MJ, McClintock MK. Abstract SY04-02: Environmental stress and breast cancer biology: What is the link Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Sy04-02  0.799
2010 Gehlert SJ, Polite BN, Grushko TA, Cipriano T, Charoenthammaraksa S, Franklin Z, Conzen SD, McClintock M, Olopade OI. Social, biological, and tumor characteristics of 139 African American (AA) women with newly diagnosed breast cancer in Chicago. Journal of Clinical Oncology. 28: 6064-6064. DOI: 10.1200/Jco.2010.28.15_Suppl.6064  0.414
2010 Conzen SD, McClintock MK. Abstract ED07-04: Identifying environment‐gene interactions that link social stress to altered cancer biology Cancer Prevention Research. 3. DOI: 10.1158/1940-6207.Prev-09-Ed07-04  0.501
2010 Melhem-Bertrandt A, Conzen SD. The Relationship Between Psychosocial Stressors and Breast Cancer Biology Current Breast Cancer Reports. 2: 130-137. DOI: 10.1007/S12609-010-0021-5  0.46
2009 Hermes GL, Delgado B, Tretiakova M, Cavigelli SA, Krausz T, Conzen SD, McClintock MK. Social isolation dysregulates endocrine and behavioral stress while increasing malignant burden of spontaneous mammary tumors. Proceedings of the National Academy of Sciences of the United States of America. 106: 22393-8. PMID 20018726 DOI: 10.1073/Pnas.0910753106  0.433
2009 Williams JB, Pang D, Delgado B, Kocherginsky M, Tretiakova M, Krausz T, Pan D, He J, McClintock MK, Conzen SD. A model of gene-environment interaction reveals altered mammary gland gene expression and increased tumor growth following social isolation. Cancer Prevention Research (Philadelphia, Pa.). 2: 850-61. PMID 19789294 DOI: 10.1158/1940-6207.Capr-08-0238  0.481
2009 Jansen SA, Conzen SD, Fan X, Markiewicz EJ, Newstead GM, Karczmar GS. Magnetic resonance imaging of the natural history of in situ mammary neoplasia in transgenic mice: a pilot study. Breast Cancer Research : Bcr. 11: R65. PMID 19732414 DOI: 10.1186/Bcr2357  0.344
2009 Luca F, Kashyap S, Southard C, Zou M, Witonsky D, Di Rienzo A, Conzen SD. Adaptive variation regulates the expression of the human SGK1 gene in response to stress. Plos Genetics. 5: e1000489. PMID 19461886 DOI: 10.1371/Journal.Pgen.1000489  0.33
2009 Melhem A, Yamada SD, Fleming GF, Delgado B, Brickley DR, Wu W, Kocherginsky M, Conzen SD. Administration of glucocorticoids to ovarian cancer patients is associated with expression of the anti-apoptotic genes SGK1 and MKP1/DUSP1 in ovarian tissues. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 3196-204. PMID 19383827 DOI: 10.1158/1078-0432.Ccr-08-2131  0.422
2009 Belova L, Delgado B, Kocherginsky M, Melhem A, Olopade OI, Conzen SD. Glucocorticoid receptor expression in breast cancer associates with older patient age. Breast Cancer Research and Treatment. 116: 441-7. PMID 18668364 DOI: 10.1007/S10549-008-0136-9  0.486
2009 Jansen S, Conzen S, Newstead G, Markiewicz E, Karczmar G. In vivomagnetic resonance imaging of the progression of murine ductal carcinomain situ: finding timescales and predictors of future invasion. Cancer Research. 69: 6011. DOI: 10.1158/0008-5472.Sabcs-6011  0.423
2009 Hahn O, Ma C, Lin L, Hou D, Sattar H, Olopade F, Nanda R, Hoffman P, Naughton M, Pluard T, Watson M, Ellis M, Conzen S, Fleming G. A phase II trial of a mammalian target of rapamycin inhibitor, temsirolimus, in patients with metastatic breast cancer. Cancer Research. 69: 407. DOI: 10.1158/0008-5472.Sabcs-407  0.376
2008 Jansen SA, Conzen SD, Fan X, Krausz T, Zamora M, Foxley S, River J, Newstead GM, Karczmar GS. Detection of in situ mammary cancer in a transgenic mouse model: in vitro and in vivo MRI studies demonstrate histopathologic correlation. Physics in Medicine and Biology. 53: 5481-93. PMID 18780960 DOI: 10.1088/0031-9155/53/19/014  0.364
2008 Conzen SD. Minireview: nuclear receptors and breast cancer. Molecular Endocrinology (Baltimore, Md.). 22: 2215-28. PMID 18417735 DOI: 10.1210/Me.2007-0421  0.507
2008 Pew T, Zou M, Brickley DR, Conzen SD. Glucocorticoid (GC)-mediated down-regulation of urokinase plasminogen activator expression via the serum and GC regulated kinase-1/forkhead box O3a pathway. Endocrinology. 149: 2637-45. PMID 18239069 DOI: 10.1210/En.2007-1096  0.473
2007 Conzen S, Hahn O, Vanderpuye V, Fleming G, Olopade F, Haraf D, Jaskowiak N, Heimann R. Phase I study of preoperative chemoradiation therapy in unresectable locally advanced breast cancer (LABC) Journal of Clinical Oncology. 25: 11097-11097. DOI: 10.1200/Jco.2007.25.18_Suppl.11097  0.389
2006 Petrella A, Ercolino SF, Festa M, Gentilella A, Tosco A, Conzen SD, Parente L. Dexamethasone inhibits TRAIL-induced apoptosis of thyroid cancer cells via Bcl-xL induction. European Journal of Cancer (Oxford, England : 1990). 42: 3287-93. PMID 17070682 DOI: 10.1016/J.Ejca.2006.07.018  0.347
2006 Belova L, Sharma S, Brickley DR, Nicolarsen JR, Patterson C, Conzen SD. Ubiquitin-proteasome degradation of serum- and glucocorticoid-regulated kinase-1 (SGK-1) is mediated by the chaperone-dependent E3 ligase CHIP. The Biochemical Journal. 400: 235-44. PMID 16895519 DOI: 10.1042/Bj20060905  0.327
2006 Bogusz AM, Brickley DR, Pew T, Conzen SD. A novel N-terminal hydrophobic motif mediates constitutive degradation of serum- and glucocorticoid-induced kinase-1 by the ubiquitin-proteasome pathway. The Febs Journal. 273: 2913-28. PMID 16817852 DOI: 10.1111/J.1742-4658.2006.05304.X  0.681
2006 Pang D, Kocherginsky M, Krausz T, Kim SY, Conzen SD. Dexamethasone decreases xenograft response to Paclitaxel through inhibition of tumor cell apoptosis. Cancer Biology & Therapy. 5: 933-40. PMID 16775428 DOI: 10.4161/Cbt.5.8.2875  0.429
2006 Wu W, Zou M, Brickley DR, Pew T, Conzen SD. Glucocorticoid receptor activation signals through forkhead transcription factor 3a in breast cancer cells. Molecular Endocrinology (Baltimore, Md.). 20: 2304-14. PMID 16690749 DOI: 10.1210/Me.2006-0131  0.48
2005 Sahoo S, Brickley DR, Kocherginsky M, Conzen SD. Coordinate expression of the PI3-kinase downstream effectors serum and glucocorticoid-induced kinase (SGK-1) and Akt-1 in human breast cancer. European Journal of Cancer (Oxford, England : 1990). 41: 2754-9. PMID 16246546 DOI: 10.1016/J.Ejca.2005.07.018  0.418
2005 McClintock MK, Conzen SD, Gehlert S, Masi C, Olopade F. Mammary cancer and social interactions: identifying multiple environments that regulate gene expression throughout the life span. The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences. 60: 32-41. PMID 15863708 DOI: 10.1093/Geronb/60.Special_Issue_1.32  0.439
2005 Kao J, Conzen SD, Jaskowiak NT, Song DH, Recant W, Singh R, Masters GA, Fleming GF, Heimann R. Concomitant radiation therapy and paclitaxel for unresectable locally advanced breast cancer: results from two consecutive phase I/II trials. International Journal of Radiation Oncology, Biology, Physics. 61: 1045-53. PMID 15752883 DOI: 10.1016/J.Ijrobp.2004.07.714  0.326
2005 Wu W, Pew T, Zou M, Pang D, Conzen SD. Glucocorticoid receptor-induced MAPK phosphatase-1 (MPK-1) expression inhibits paclitaxel-associated MAPK activation and contributes to breast cancer cell survival. The Journal of Biological Chemistry. 280: 4117-24. PMID 15590693 DOI: 10.1074/Jbc.M411200200  0.48
2004 Wu W, Chaudhuri S, Brickley DR, Pang D, Karrison T, Conzen SD. Microarray analysis reveals glucocorticoid-regulated survival genes that are associated with inhibition of apoptosis in breast epithelial cells. Cancer Research. 64: 1757-64. PMID 14996737 DOI: 10.1158/0008-5472.Can-03-2546  0.439
2004 Poelman SM, Heimann R, Fleming GF, Recant WM, Conzen SD. Invariant p53 immunostaining in primary and recurrent breast cancer. European Journal of Cancer (Oxford, England : 1990). 40: 28-32. PMID 14687786 DOI: 10.1016/S0959-8049(03)00661-0  0.39
2003 Ramljak D, Coticchia CM, Nishanian TG, Saji M, Ringel MD, Conzen SD, Dickson RB. Epidermal growth factor inhibition of c-Myc-mediated apoptosis through Akt and Erk involves Bcl-xL upregulation in mammary epithelial cells. Experimental Cell Research. 287: 397-410. PMID 12837294 DOI: 10.1016/S0014-4827(03)00135-6  0.338
2003 Benz C, Clark G, Conzen S, Dorn R, Fuqua S, Gralow J, Greene G, Heimann R, Hellman S, Lippman M, Rosen N, Weiner L. Consensus statement: Expedition Inspiration fund for breast cancer research meeting 2002. Breast Cancer Research and Treatment. 78: 127-31. PMID 12611465 DOI: 10.1023/A:1022108507821  0.351
2002 Brickley DR, Mikosz CA, Hagan CR, Conzen SD. Ubiquitin modification of serum and glucocorticoid-induced protein kinase-1 (SGK-1). The Journal of Biological Chemistry. 277: 43064-70. PMID 12218062 DOI: 10.1074/Jbc.M207604200  0.377
2001 Mikosz CA, Brickley DR, Sharkey MS, Moran TW, Conzen SD. Glucocorticoid receptor-mediated protection from apoptosis is associated with induction of the serine/threonine survival kinase gene, sgk-1. The Journal of Biological Chemistry. 276: 16649-54. PMID 11278764 DOI: 10.1074/Jbc.M010842200  0.43
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