Year |
Citation |
Score |
2019 |
Quintero JE, Ai Y, Andersen AH, Hardy P, Grondin R, Guduru Z, Gash DM, Gerhardt GA, Zhang Z. Validations of apomorphine-induced BOLD activation correlations in hemiparkinsonian rhesus macaques. Neuroimage. Clinical. 22: 101724. PMID 30822717 DOI: 10.1016/J.Nicl.2019.101724 |
0.409 |
|
2018 |
Grondin R, Littrell OM, Zhang Z, Ai Y, Huettl P, Pomerleau F, Quintero JE, Andersen AH, Stenslik MJ, Bradley LH, Lemmon J, O'Neill MJ, Gash DM, Gerhardt GA. GDNF revisited: A novel mammalian cell-derived variant form of GDNF increases dopamine turnover and improves brain biodistribution. Neuropharmacology. PMID 29857941 DOI: 10.1016/J.Neuropharm.2018.05.014 |
0.413 |
|
2018 |
Stenslik MJ, Evans A, Pomerleau F, Weeks R, Huettl P, Foreman E, Turchan-Cholewo J, Andersen A, Cass WA, Zhang Z, Grondin RC, Gash DM, Gerhardt GA, Bradley LH. Methodology and effects of repeated intranasal delivery of DNSP-11 in awake Rhesus macaques. Journal of Neuroscience Methods. PMID 29614295 DOI: 10.1016/J.Jneumeth.2018.03.006 |
0.321 |
|
2017 |
Zhang R, Andersen AH, Hardy PA, Forman E, Evans A, Ai Y, Yue J, Yue G, Gash DM, Grondin R, Zhang Z. Objectively measuring effects of electro-acupuncture in parkinsonian rhesus monkeys. Brain Research. PMID 29017909 DOI: 10.1016/J.Brainres.2017.10.006 |
0.394 |
|
2016 |
Grondin R, Ai Y, Hardy PA, Butt MT, Nelson BD, Lemmon JD, Bumcrot D, Gash DM, Gerhardt GA, Zhang Z. Continuous intranigral infusion is not associated with observable behavioral deficits or marked pathology: a preclinical safety study. Journal of Neurosurgery. 1-10. PMID 27231974 DOI: 10.3171/2016.2.Jns152295 |
0.353 |
|
2015 |
Grondin R, Ge P, Chen Q, Sutherland JE, Zhang Z, Gash DM, Stiles DK, Stewart GR, Sah DW, Kaemmerer WF. Onset Time and Durability of Huntingtin Suppression in Rhesus Putamen After Direct Infusion of Antihuntingtin siRNA. Molecular Therapy. Nucleic Acids. 4: e245. PMID 26125484 DOI: 10.1038/Mtna.2015.20 |
0.31 |
|
2015 |
Pandya JD, Grondin R, Yonutas HM, Haghnazar H, Gash DM, Zhang Z, Sullivan PG. Decreased mitochondrial bioenergetics and calcium buffering capacity in the basal ganglia correlates with motor deficits in a nonhuman primate model of aging. Neurobiology of Aging. 36: 1903-13. PMID 25726361 DOI: 10.1016/J.Neurobiolaging.2015.01.018 |
0.33 |
|
2015 |
Andersen AH, Hardy PA, Forman E, Gerhardt GA, Gash DM, Grondin RC, Zhang Z. Pharmacologic MRI (phMRI) as a tool to differentiate Parkinson's disease-related from age-related changes in basal ganglia function. Neurobiology of Aging. 36: 1174-82. PMID 25443764 DOI: 10.1016/J.Neurobiolaging.2014.10.014 |
0.393 |
|
2014 |
Fan XT, Zhao F, Ai Y, Andersen A, Hardy P, Ling F, Gerhardt GA, Zhang Z, Quintero JE. Cortical glutamate levels decrease in a non-human primate model of dopamine deficiency. Brain Research. 1552: 34-40. PMID 24398457 DOI: 10.1016/J.Brainres.2013.12.035 |
0.366 |
|
2012 |
Leak RK, Garbett KA, Dettmer AM, Zhang Z, Mirnics K, Cameron JL. Physical activity is linked to ceruloplasmin in the striatum of intact but not MPTP-treated primates. Cell and Tissue Research. 350: 401-7. PMID 22940761 DOI: 10.1007/S00441-012-1488-3 |
0.682 |
|
2012 |
Stiles DK, Zhang Z, Ge P, Nelson B, Grondin R, Ai Y, Hardy P, Nelson PT, Guzaev AP, Butt MT, Charisse K, Kosovrasti V, Tchangov L, Meys M, Maier M, et al. Widespread suppression of huntingtin with convection-enhanced delivery of siRNA. Experimental Neurology. 233: 463-71. PMID 22119622 DOI: 10.1016/J.Expneurol.2011.11.020 |
0.343 |
|
2012 |
Zhang Z, Andersen A, Hardy P, Ai Y, Grondin R, Gash D, Gerhardt G. 2.150 A POSSIBLE NEW BIOMARKER FOR PARKINSON'S DISEASE: PHARMACOLOGICAL MRI (PHMRI) TO DISCRIMINATE ANIMALS WITH MPTP-VERSUS AGE-RELATED PARKINSONISM IN RHESUS MONKEYS Parkinsonism & Related Disorders. 18: S114. DOI: 10.1016/S1353-8020(11)70522-3 |
0.371 |
|
2010 |
Zhao F, Fan X, Grondin R, Edwards R, Forman E, Moorehead J, Gerhardt G, Wang X, Zhang Z. Improved methods for electroacupuncture and electromyographic recordings in normal and parkinsonian rhesus monkeys. Journal of Neuroscience Methods. 192: 199-206. PMID 20654649 DOI: 10.1016/J.Jneumeth.2010.07.016 |
0.351 |
|
2010 |
Bradley LH, Fuqua J, Richardson A, Turchan-Cholewo J, Ai Y, Kelps KA, Glass JD, He X, Zhang Z, Grondin R, Littrell OM, Huettl P, Pomerleau F, Gash DM, Gerhardt GA. Dopamine neuron stimulating actions of a GDNF propeptide. Plos One. 5: e9752. PMID 20305789 DOI: 10.1371/Journal.Pone.0009752 |
0.404 |
|
2010 |
Lopresti BJ, Dettmar A, Leak R, Rockcastle NJ, Zigmond MJ, Mathis C, Zhang Z, Cameron J. Regular exercise training protects against MPTP-damage to nigrostriatal dopamine neurons in nonhuman primates Neuroimage. 52: S66. DOI: 10.1016/J.Neuroimage.2010.04.051 |
0.537 |
|
2008 |
Ding F, Luan L, Ai Y, Walton A, Gerhardt GA, Gash DM, Grondin R, Zhang Z. Development of a stable, early stage unilateral model of Parkinson's disease in middle-aged rhesus monkeys. Experimental Neurology. 212: 431-9. PMID 18547564 DOI: 10.1016/J.Expneurol.2008.04.027 |
0.383 |
|
2008 |
Luan L, Ding F, Ai Y, Andersen A, Hardy P, Forman E, Gerhardt GA, Gash DM, Grondin R, Zhang Z. Pharmacological MRI (phMRI) monitoring of treatment in hemiparkinsonian rhesus monkeys. Cell Transplantation. 17: 417-25. PMID 18522244 DOI: 10.3727/096368908784423319 |
0.391 |
|
2008 |
Xin T, Ai Y, Gerhardt G, Gash D, Zhang Z. Globus pallidus plays a critical role in neurotrophic factor induced functional improvements in hemiparkinsonian monkeys. Biochemical and Biophysical Research Communications. 370: 434-9. PMID 18381061 DOI: 10.1016/J.Bbrc.2008.03.108 |
0.354 |
|
2008 |
Grondin R, Zhang Z, Ai Y, Ding F, Walton AA, Surgener SP, Gerhardt GA, Gash DM. Intraputamenal infusion of exogenous neurturin protein restores motor and dopaminergic function in the globus pallidus of MPTP-lesioned rhesus monkeys. Cell Transplantation. 17: 373-381. DOI: 10.3727/096368908784423256 |
0.373 |
|
2008 |
Lopresti BJ, Zhang Z, Zigmond M, Leak R, Mathis C, Cameron J. Increased survival of nigrostriatal dopaminergic neurons following a toxic MPTP insult in the exercising primate: A [11C]DTBZ PET study Neuroimage. 41: T55. DOI: 10.1016/J.Neuroimage.2008.04.229 |
0.528 |
|
2008 |
Leak RK, Zhang Z, Castro S, Lopresti B, Mathis C, Zigmond M, Cameron J. Impact of exercise on caudate and putamen in a non-human primate model of Parkinson's disease Neuroimage. 41: T129. DOI: 10.1016/J.Neuroimage.2008.04.097 |
0.537 |
|
2007 |
Quintero JE, Day BK, Zhang Z, Grondin R, Stephens ML, Huettl P, Pomerleau F, Gash DM, Gerhardt GA. Amperometric measures of age-related changes in glutamate regulation in the cortex of rhesus monkeys. Experimental Neurology. 208: 238-46. PMID 17927982 DOI: 10.1016/J.Expneurol.2007.08.002 |
0.305 |
|
2007 |
Cass WA, Grondin R, Andersen AH, Zhang Z, Hardy PA, Hussey-Andersen LK, Rayens WS, Gerhardt GA, Gash DM. Iron accumulation in the striatum predicts aging-related decline in motor function in rhesus monkeys. Neurobiology of Aging. 28: 258-71. PMID 16442671 DOI: 10.1016/J.Neurobiolaging.2005.12.010 |
0.351 |
|
2006 |
Salvatore MF, Ai Y, Fischer B, Zhang AM, Grondin RC, Zhang Z, Gerhardt GA, Gash DM. Point source concentration of GDNF may explain failure of phase II clinical trial. Experimental Neurology. 202: 497-505. PMID 16962582 DOI: 10.1016/J.Expneurol.2006.07.015 |
0.321 |
|
2006 |
Zhang Z, Andersen AH, Ai Y, Loveland A, Hardy PA, Gerhardt GA, Gash DM. Assessing nigrostriatal dysfunctions by pharmacological MRI in parkinsonian rhesus macaques. Neuroimage. 33: 636-43. PMID 16949305 DOI: 10.1016/J.Neuroimage.2006.07.004 |
0.405 |
|
2005 |
Gash DM, Zhang Z, Ai Y, Grondin R, Coffey R, Gerhardt GA. Trophic factor distribution predicts functional recovery in parkinsonian monkeys. Annals of Neurology. 58: 224-33. PMID 16049934 DOI: 10.1002/Ana.20549 |
0.412 |
|
2004 |
Maswood N, Young J, Tilmont E, Zhang Z, Gash DM, Gerhardt GA, Grondin R, Roth GS, Mattison J, Lane MA, Carson RE, Cohen RM, Mouton PR, Quigley C, Mattson MP, et al. Caloric restriction increases neurotrophic factor levels and attenuates neurochemical and behavioral deficits in a primate model of Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. 101: 18171-6. PMID 15604149 DOI: 10.1073/Pnas.0405831102 |
0.397 |
|
2003 |
Grondin R, Zhang Z, Ai Y, Gash DM, Gerhardt GA. Intracranial delivery of proteins and peptides as a therapy for neurodegenerative diseases. Progress in Drug Research. Fortschritte Der Arzneimittelforschung. Progrã¨S Des Recherches Pharmaceutiques. 61: 101-23. PMID 14674610 DOI: 10.1007/978-3-0348-8049-7_4 |
0.389 |
|
2003 |
Ai Y, Markesbery W, Zhang Z, Grondin R, Elseberry D, Gerhardt GA, Gash DM. Intraputamenal infusion of GDNF in aged rhesus monkeys: distribution and dopaminergic effects. The Journal of Comparative Neurology. 461: 250-61. PMID 12724841 DOI: 10.1002/Cne.10689 |
0.368 |
|
2003 |
Grondin R, Cass WA, Zhang Z, Stanford JA, Gash DM, Gerhardt GA. Glial cell line-derived neurotrophic factor increases stimulus-evoked dopamine release and motor speed in aged rhesus monkeys. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 1974-80. PMID 12629203 DOI: 10.1523/Jneurosci.23-05-01974.2003 |
0.381 |
|
2002 |
Maswood N, Grondin R, Zhang Z, Stanford JA, Surgener SP, Gash DM, Gerhardt GA. Effects of chronic intraputamenal infusion of glial cell line-derived neurotrophic factor (GDNF) in aged Rhesus monkeys. Neurobiology of Aging. 23: 881-9. PMID 12392792 DOI: 10.1016/S0197-4580(02)00022-2 |
0.417 |
|
2002 |
Grondin R, Zhang Z, Yi A, Cass WA, Maswood N, Andersen AH, Elsberry DD, Klein MC, Gerhardt GA, Gash DM. Chronic, controlled GDNF infusion promotes structural and functional recovery in advanced parkinsonian monkeys. Brain : a Journal of Neurology. 125: 2191-201. PMID 12244077 DOI: 10.1093/Brain/Awf234 |
0.425 |
|
2002 |
Andersen AH, Zhang Z, Barber T, Rayens WS, Zhang J, Grondin R, Hardy P, Gerhardt GA, Gash DM. Functional MRI studies in awake rhesus monkeys: methodological and analytical strategies. Journal of Neuroscience Methods. 118: 141-52. PMID 12204305 DOI: 10.1016/S0165-0270(02)00123-1 |
0.305 |
|
2002 |
Gerhardt GA, Cass WA, Yi A, Zhang Z, Gash DM. Changes in somatodendritic but not terminal dopamine regulation in aged rhesus monkeys. Journal of Neurochemistry. 80: 168-77. PMID 11796755 DOI: 10.1046/J.0022-3042.2001.00684.X |
0.387 |
|
2001 |
Grondin R, Zhang Z, Elsberry DD, Gerhardt GA, Gash DM. Chronic Intracerebral Delivery of Trophic Factors via a Programmable Pump as a Treatment for Parkinsonism. Methods in Molecular Medicine. 62: 257-67. PMID 21318781 DOI: 10.1385/1-59259-142-6:257 |
0.38 |
|
2001 |
Zhang Z, Andersen A, Grondin R, Barber T, Avison R, Gerhardt G, Gash D. Pharmacological MRI mapping of age-associated changes in basal ganglia circuitry of awake rhesus monkeys. Neuroimage. 14: 1159-67. PMID 11697947 DOI: 10.1006/Nimg.2001.0902 |
0.418 |
|
2000 |
Zhang Z, Andersen A, Smith C, Grondin R, Gerhardt G, Gash D. Motor slowing and parkinsonian signs in aging rhesus monkeys mirror human aging. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 55: B473-80. PMID 11034220 DOI: 10.1093/Gerona/55.10.B473 |
0.321 |
|
2000 |
Zhang Z, Andersen AH, Avison MJ, Gerhardt GA, Gash DM. Functional MRI of apomorphine activation of the basal ganglia in awake rhesus monkeys. Brain Research. 852: 290-6. PMID 10678755 DOI: 10.1016/S0006-8993(99)02243-X |
0.366 |
|
2000 |
Grondin R, Zhang Z, Gerhardt GA, Gash DM. Dopaminergic therapy improves upper limb motor performance in aged rhesus monkeys. Annals of Neurology. 48: 250-253. DOI: 10.1002/1531-8249(200008)48:2<250::Aid-Ana16>3.0.Co;2-1 |
0.338 |
|
1999 |
Chen Q, Andersen AH, Zhang Z, Ovadia A, Cass WA, Gash DM, Avison MJ. Functional MRI of basal ganglia responsiveness to levodopa in parkinsonian rhesus monkeys. Experimental Neurology. 158: 63-75. PMID 10448418 DOI: 10.1006/Exnr.1999.7089 |
0.396 |
|
1999 |
Zhang Z, Zhang M, Ai Y, Avison C, Gash DM. MPTP-induced pallidal lesions in rhesus monkeys Experimental Neurology. 155: 140-149. PMID 9918713 DOI: 10.1006/Exnr.1998.6976 |
0.382 |
|
1999 |
Gerhardt GA, Cass WA, Huettl P, Brock S, Zhang Z, Gash DM. GDNF improves dopamine function in the substantia nigra but not the putamen of unilateral MPTP-lesioned rhesus monkeys. Brain Research. 817: 163-71. PMID 9889359 DOI: 10.1016/S0006-8993(98)01244-X |
0.379 |
|
1999 |
Duan W, Zhang Z, Gash DM, Mattson MP. Participation of prostate apoptosis response-4 in degeneration of dopaminergic neurons in models of Parkinson's disease Annals of Neurology. 46: 587-597. DOI: 10.1002/1531-8249(199910)46:4<587::Aid-Ana6>3.0.Co;2-M |
0.352 |
|
1998 |
Gash DM, Zhang Z, Gerhardt G. Neuroprotective and neurorestorative properties of GDNF. Annals of Neurology. 44: S121-5. PMID 9749583 DOI: 10.1002/Ana.410440718 |
0.417 |
|
1997 |
Miyoshi Y, Zhang Z, Ovadia A, Lapchak PA, Collins F, Hilt D, Lebel C, Kryscio R, Gash DM. Glial cell line-derived neurotrophic factor-levodopa interactions and reduction of side effects in parkinsonian monkeys Annals of Neurology. 42: 208-214. PMID 9266731 DOI: 10.1002/Ana.410420212 |
0.356 |
|
1996 |
Gash DM, Zhang Z, Ovadia A, Cass WA, Yi A, Simmerman L, Russell D, Martin D, Lapchak PA, Collins F, Hoffer BJ, Gerhardt GA. Functional recovery in parkinsonian monkeys treated with GDNF. Nature. 380: 252-5. PMID 8637574 DOI: 10.1038/380252A0 |
0.425 |
|
1996 |
Gerhardt GA, Cass WA, Hudson J, Henson M, Zhang Z, Ovadia A, Hoffer BJ, Gash DM. In vivo electrochemical studies of dopamine overflow and clearance in the striatum of normal and MPTP-treated rhesus monkeys. Journal of Neurochemistry. 66: 579-88. PMID 8592127 DOI: 10.1046/J.1471-4159.1996.66020579.X |
0.37 |
|
1995 |
Gash DM, Zhang Z, Cass WA, Ovadia A, Simmerman L, Martin D, Russell D, Collins F, Hoffer BJ, Gerhardt GA. Morphological and functional effects of intranigrally administered GDNF in normal rhesus monkeys. The Journal of Comparative Neurology. 363: 345-58. PMID 8847404 DOI: 10.1002/Cne.903630302 |
0.401 |
|
1995 |
Gerhardt GA, Cass WA, Henson M, Zhang Z, Ovadia A, Hoffer BJ, Gash DM. Age-related changes in potassium-evoked overflow of dopamine in the striatum of the rhesus monkey. Neurobiology of Aging. 16: 939-46. PMID 8622785 DOI: 10.1016/0197-4580(95)02013-6 |
0.352 |
|
1995 |
Ovadia A, Zhang Z, Gash DM. Increased susceptibility to MPTP toxicity in middle-aged rhesus monkeys Neurobiology of Aging. 16: 931-937. PMID 8622784 DOI: 10.1016/0197-4580(95)02012-8 |
0.318 |
|
1995 |
Cass WA, Gerhardt GA, Zhang Z, Ovadia A, Gash DM. Increased dopamine clearance in the non-lesioned striatum of rhesus monkeys with unilateral 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) striatal lesions. Neuroscience Letters. 185: 52-5. PMID 7731554 DOI: 10.1016/0304-3940(94)11223-6 |
0.336 |
|
1994 |
Greenamyre JT, Eller RV, Zhang Z, Ovadia A, Kurlan R, Gash DM. Antiparkinsonian effects of remacemide hydrochloride, a glutamate antagonist, in rodent and primate models of Parkinson's disease. Annals of Neurology. 35: 655-61. PMID 8210221 DOI: 10.1002/Ana.410350605 |
0.33 |
|
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