Year |
Citation |
Score |
2024 |
Drawshy Z, Neiman D, Fridlich O, Peretz A, Magenheim J, Rozo AV, Doliba NM, Stoffers DA, Kaestner KH, Schatz DA, Wasserfall C, Campbell-Thompson M, Shapiro J, Kaplan T, Shemer R, et al. DNA methylation-based assessment of cell composition in human pancreas and islets. Diabetes. PMID 38266068 DOI: 10.2337/db23-0704 |
0.411 |
|
2022 |
Yang X, Raum JC, Kim J, Yu R, Yang J, Rice G, Li C, Won KJ, Stanescu DE, Stoffers DA. A PDX1 cistrome and single-cell transcriptome resource of the developing pancreas. Development (Cambridge, England). PMID 35708349 DOI: 10.1242/dev.200432 |
0.312 |
|
2022 |
Doliba NM, Rozo AV, Roman J, Qin W, Traum D, Gao L, Liu J, Manduchi E, Liu C, Golson ML, Vahedi G, Naji A, Matschinsky FM, Atkinson MA, Powers AC, ... ... Stoffers DA, et al. α Cell dysfunction in islets from nondiabetic, glutamic acid decarboxylase autoantibody-positive individuals. The Journal of Clinical Investigation. 132. PMID 35642629 DOI: 10.1172/JCI156243 |
0.437 |
|
2021 |
Zhu X, Oguh A, Gingerich MA, Soleimanpour SA, Stoffers DA, Gannon M. Cell Cycle Regulation of the Pdx1 Transcription Factor in Developing Pancreas and Insulin-Producing β Cells. Diabetes. PMID 33526589 DOI: 10.2337/db20-0599 |
0.446 |
|
2020 |
Mosleh E, Ou K, Haemmerle MW, Tembo T, Yuhas A, Carboneau BA, Townsend SE, Bosma KJ, Gannon M, O'Brien RM, Stoffers DA, Golson ML. Ins1-Cre and Ins1-CreER gene replacement alleles are susceptible to silencing by DNA hypermethylation. Endocrinology. PMID 32267917 DOI: 10.1210/Endocr/Bqaa054 |
0.419 |
|
2020 |
Good AL, Stoffers DA. Stress-Induced Translational Regulation Mediated by RNA Binding Proteins: Key Links to β-Cell Failure in Diabetes. Diabetes. 69: 499-507. PMID 32198193 DOI: 10.2337/Dbi18-0068 |
0.831 |
|
2020 |
Baeyens L, Lemper M, Leuckx G, De Groef S, Bonfanti P, Stangé G, Shemer R, Nord C, Scheel DW, Pan FC, Ahlgren U, Gu G, Stoffers DA, Dor Y, Ferrer J, et al. Retraction Note: Transient cytokine treatment induces acinar cell reprogramming and regenerates functional beta cell mass in diabetic mice. Nature Biotechnology. PMID 32066957 DOI: 10.1038/S41587-020-0426-2 |
0.455 |
|
2020 |
Doliba NM, Rozo AV, Qin W, Roman J, Liu C, Naji A, Kaestner KH, Stoffers DA, Matschinsky F. 322-OR: Impairment of Alpha-Cell Bioenergetics Contributes to Increased Basal Yet Decreased Glucose Stimulated Oxygen Consumption Rates of Isolated Human Pancreatic Islets in T1DM and T2DM Diabetes. 69. DOI: 10.2337/Db20-322-Or |
0.37 |
|
2019 |
Good AL, Haemmerle MW, Oguh AU, Doliba NM, Stoffers DA. Metabolic stress activates an ERK/hnRNPK/DDX3X pathway in pancreatic β cells. Molecular Metabolism. PMID 31178390 DOI: 10.1016/J.Molmet.2019.05.009 |
0.828 |
|
2019 |
Good AL, Cannon CE, Haemmerle MW, Yang J, Stanescu DE, Doliba NM, Birnbaum MJ, Stoffers DA. JUND regulates pancreatic β cell survival during metabolic stress. Molecular Metabolism. PMID 31023625 DOI: 10.1016/J.Molmet.2019.04.007 |
0.82 |
|
2018 |
Poitout V, Satin LS, Kahn SE, Stoffers DA, Marchetti P, Gannon M, Verchere CB, Herold KC, Myers MG, Marshall SM. A Call for Improved Reporting of Human Islet Characteristics in Research Articles. Diabetes. PMID 30552106 DOI: 10.2337/Dbi18-0055 |
0.378 |
|
2018 |
Juliana CA, Yang J, Cannon CE, Good AL, Haemmerle MW, Stoffers DA. A PDX1-ATF transcriptional complex governs β cell survival during stress. Molecular Metabolism. PMID 30174228 DOI: 10.1016/J.Molmet.2018.07.007 |
0.824 |
|
2017 |
Kropp PA, Dunn JC, Carboneau BA, Stoffers DA, Gannon M. Cooperative function of Pdx1 and Oc1 in multipotent pancreatic progenitors impacts postnatal islet maturation and adaptability. American Journal of Physiology. Endocrinology and Metabolism. PMID 29351489 DOI: 10.1152/Ajpendo.00260.2017 |
0.578 |
|
2017 |
Remsberg JR, Ediger BN, Ho WY, Damle M, Li Z, Teng C, Lanzillotta C, Stoffers DA, Lazar MA. Deletion of histone deacetylase 3 in adult beta cells improves glucose tolerance via increased insulin secretion. Molecular Metabolism. 6: 30-37. PMID 28123935 DOI: 10.1016/J.Molmet.2016.11.007 |
0.82 |
|
2017 |
Juliana CA, Yang J, Rozo AV, Good A, Groff DN, Wang SZ, Green MR, Stoffers DA. ATF5 regulates β-cell survival during stress. Proceedings of the National Academy of Sciences of the United States of America. PMID 28115692 DOI: 10.1073/Pnas.1620705114 |
0.832 |
|
2016 |
Stanescu DE, Yu R, Won KJ, Stoffers DA. Single cell transcriptomic profiling of mouse pancreatic progenitors. Physiological Genomics. physiolgenomics.0011. PMID 28011883 DOI: 10.1152/Physiolgenomics.00114.2016 |
0.47 |
|
2016 |
Loyd C, Liu Y, Kim T, Holleman C, Galloway J, Bethea M, Ediger BN, Tang Y, Swain TA, Stoffers DA, Rowe GC, Young M, Steele C, Habegger KM, Hunter CS. Ldb1 Regulates Energy Homeostasis During Diet-Induced Obesity. Endocrinology. en20161791. PMID 28009534 DOI: 10.1210/En.2016-1791 |
0.809 |
|
2016 |
Ediger BN, Lim HW, Juliana C, Groff DN, Williams LT, Dominguez G, Liu JH, Taylor BL, Walp ER, Kameswaran V, Yang J, Liu C, Hunter CS, Kaestner KH, Naji A, ... ... Stoffers DA, et al. LIM domain-binding 1 maintains the terminally differentiated state of pancreatic β cells. The Journal of Clinical Investigation. PMID 27941246 DOI: 10.1172/Jci88016 |
0.834 |
|
2016 |
Burmeister MA, Ayala JE, Smouse H, Landivar-Rocha A, Brown JD, Drucker DJ, Stoffers DA, Sandoval DA, Seeley RJ, Ayala JE. "The Hypothalamic Glucagon-Like Peptide-1 (GLP-1) Receptor (GLP-1R) is Sufficient but Not Necessary for the Regulation of Energy Balance and Glucose Homeostasis in Mice". Diabetes. PMID 27908915 DOI: 10.2337/Db16-1102 |
0.322 |
|
2016 |
Henley KD, Stanescu DE, Kropp PA, Wright CV, Won KJ, Stoffers DA, Gannon M. Threshold-Dependent Cooperativity of Pdx1 and Oc1 in Pancreatic Progenitors Establishes Competency for Endocrine Differentiation and β-Cell Function. Cell Reports. PMID 27292642 DOI: 10.1016/J.Celrep.2016.05.040 |
0.509 |
|
2015 |
Soleimanpour SA, Ferrari AM, Raum JC, Groff DN, Yang J, Kaufman BA, Stoffers DA. Diabetes susceptibility genes Pdx1 and Clec16a function in a pathway regulating mitophagy in β-cells. Diabetes. PMID 26085571 DOI: 10.2337/Db15-0376 |
0.471 |
|
2015 |
Raum JC, Soleimanpour SA, Groff DN, Coré N, Fasano L, Garratt AN, Dai C, Powers AC, Stoffers DA. Tshz1 Regulates Pancreatic β-Cell Maturation. Diabetes. 64: 2905-14. PMID 25918232 DOI: 10.2337/Db14-1443 |
0.626 |
|
2015 |
Wang A, Yue F, Li Y, Xie R, Harper T, Patel NA, Muth K, Palmer J, Qiu Y, Wang J, Lam DK, Raum JC, Stoffers DA, Ren B, Sander M. Epigenetic priming of enhancers predicts developmental competence of hESC-derived endodermal lineage intermediates. Cell Stem Cell. 16: 386-99. PMID 25842977 DOI: 10.1016/J.Stem.2015.02.013 |
0.413 |
|
2014 |
Cannon CE, Titchenell PM, Groff DN, El Ouaamari A, Kulkarni RN, Birnbaum MJ, Stoffers DA. The Polycomb protein, Bmi1, regulates insulin sensitivity. Molecular Metabolism. 3: 794-802. PMID 25379404 DOI: 10.1016/J.Molmet.2014.08.002 |
0.694 |
|
2014 |
Ediger BN, Du A, Liu J, Hunter CS, Walp ER, Schug J, Kaestner KH, Stein R, Stoffers DA, May CL. Islet-1 Is essential for pancreatic β-cell function. Diabetes. 63: 4206-17. PMID 25028525 DOI: 10.2337/Db14-0096 |
0.828 |
|
2014 |
Soleimanpour SA, Gupta A, Bakay M, Ferrari AM, Groff DN, Fadista J, Spruce LA, Kushner JA, Groop L, Seeholzer SH, Kaufman BA, Hakonarson H, Stoffers DA. The diabetes susceptibility gene Clec16a regulates mitophagy. Cell. 157: 1577-90. PMID 24949970 DOI: 10.1016/J.Cell.2014.05.016 |
0.534 |
|
2014 |
Liew CW, Assmann A, Templin AT, Raum JC, Lipson KL, Rajan S, Qiang G, Hu J, Kawamori D, Lindberg I, Philipson LH, Sonenberg N, Goldfine AB, Stoffers DA, Mirmira RG, et al. Insulin regulates carboxypeptidase E by modulating translation initiation scaffolding protein eIF4G1 in pancreatic β cells. Proceedings of the National Academy of Sciences of the United States of America. 111: E2319-28. PMID 24843127 DOI: 10.1073/Pnas.1323066111 |
0.507 |
|
2014 |
Smith EP, An Z, Wagner C, Lewis AG, Cohen EB, Li B, Mahbod P, Sandoval D, Perez-Tilve D, Tamarina N, Philipson LH, Stoffers DA, Seeley RJ, D'Alessio DA. The role of β cell glucagon-like peptide-1 signaling in glucose regulation and response to diabetes drugs. Cell Metabolism. 19: 1050-7. PMID 24836562 DOI: 10.1016/J.Cmet.2014.04.005 |
0.516 |
|
2014 |
Gao T, McKenna B, Li C, Reichert M, Nguyen J, Singh T, Yang C, Pannikar A, Doliba N, Zhang T, Stoffers DA, Edlund H, Matschinsky F, Stein R, Stanger BZ. Pdx1 maintains β cell identity and function by repressing an α cell program. Cell Metabolism. 19: 259-71. PMID 24506867 DOI: 10.1016/J.Cmet.2013.12.002 |
0.546 |
|
2014 |
Baeyens L, Lemper M, Leuckx G, De Groef S, Bonfanti P, Stangé G, Shemer R, Nord C, Scheel DW, Pan FC, Ahlgren U, Gu G, Stoffers DA, Dor Y, Ferrer J, et al. Transient cytokine treatment induces acinar cell reprogramming and regenerates functional beta cell mass in diabetic mice. Nature Biotechnology. 32: 76-83. PMID 24240391 DOI: 10.1038/Nbt.2747 |
0.523 |
|
2013 |
Soleimanpour SA, Stoffers DA. The pancreatic β cell and type 1 diabetes: innocent bystander or active participant? Trends in Endocrinology and Metabolism: Tem. 24: 324-31. PMID 23647931 DOI: 10.1016/J.Tem.2013.03.005 |
0.554 |
|
2013 |
Wilson-Pérez HE, Chambers AP, Ryan KK, Li B, Sandoval DA, Stoffers D, Drucker DJ, Pérez-Tilve D, Seeley RJ. Vertical sleeve gastrectomy is effective in two genetic mouse models of glucagon-like Peptide 1 receptor deficiency. Diabetes. 62: 2380-5. PMID 23434938 DOI: 10.2337/Db12-1498 |
0.308 |
|
2013 |
Wang Y, Liu J, Liu C, Naji A, Stoffers DA. MicroRNA-7 regulates the mTOR pathway and proliferation in adult pancreatic β-cells. Diabetes. 62: 887-95. PMID 23223022 DOI: 10.2337/Db12-0451 |
0.345 |
|
2012 |
Khoo C, Yang J, Weinrott SA, Kaestner KH, Naji A, Schug J, Stoffers DA. Research resource: the pdx1 cistrome of pancreatic islets. Molecular Endocrinology (Baltimore, Md.). 26: 521-33. PMID 22322596 DOI: 10.1210/Me.2011-1231 |
0.824 |
|
2012 |
Kolesar JE, Taguchi YV, Cramer RL, Wang C, Chou S, Soleimanpour SA, Stoffers DA, Kaufman BA. Evidence for mitochondrial adaptation to chronic glucose exposure in beta cells Mitochondrion. 12: 587-588. DOI: 10.1016/J.Mito.2012.07.095 |
0.357 |
|
2011 |
Pinney SE, Jaeckle Santos LJ, Han Y, Stoffers DA, Simmons RA. Exendin-4 increases histone acetylase activity and reverses epigenetic modifications that silence Pdx1 in the intrauterine growth retarded rat. Diabetologia. 54: 2606-14. PMID 21779870 DOI: 10.1007/S00125-011-2250-1 |
0.47 |
|
2011 |
Khoo C, Yang J, Rajpal G, Wang Y, Liu J, Arvan P, Stoffers DA. Endoplasmic reticulum oxidoreductin-1-like β (ERO1lβ) regulates susceptibility to endoplasmic reticulum stress and is induced by insulin flux in β-cells. Endocrinology. 152: 2599-608. PMID 21540283 DOI: 10.1210/En.2010-1420 |
0.832 |
|
2011 |
Pinney SE, Oliver-Krasinski J, Ernst L, Hughes N, Patel P, Stoffers DA, Russo P, De León DD. Neonatal diabetes and congenital malabsorptive diarrhea attributable to a novel mutation in the human neurogenin-3 gene coding sequence. The Journal of Clinical Endocrinology and Metabolism. 96: 1960-5. PMID 21490072 DOI: 10.1210/Jc.2011-0029 |
0.747 |
|
2010 |
Yang Y, Gurung B, Wu T, Wang H, Stoffers DA, Hua X. Reversal of preexisting hyperglycemia in diabetic mice by acute deletion of the Men1 gene. Proceedings of the National Academy of Sciences of the United States of America. 107: 20358-63. PMID 21059956 DOI: 10.1073/Pnas.1012257107 |
0.493 |
|
2010 |
Liu J, Wang Y, Birnbaum MJ, Stoffers DA. Three-amino-acid-loop-extension homeodomain factor Meis3 regulates cell survival via PDK1. Proceedings of the National Academy of Sciences of the United States of America. 107: 20494-9. PMID 21059917 DOI: 10.1073/Pnas.1007001107 |
0.534 |
|
2010 |
Soleimanpour SA, Crutchlow MF, Ferrari AM, Raum JC, Groff DN, Rankin MM, Liu C, De León DD, Naji A, Kushner JA, Stoffers DA. Calcineurin signaling regulates human islet {beta}-cell survival. The Journal of Biological Chemistry. 285: 40050-9. PMID 20943662 DOI: 10.1074/Jbc.M110.154955 |
0.522 |
|
2010 |
Claiborn KC, Sachdeva MM, Cannon CE, Groff DN, Singer JD, Stoffers DA. Pcif1 modulates Pdx1 protein stability and pancreatic β cell function and survival in mice. The Journal of Clinical Investigation. 120: 3713-21. PMID 20811152 DOI: 10.1172/Jci40440 |
0.833 |
|
2010 |
Nicolino M, Claiborn KC, Senée V, Boland A, Stoffers DA, Julier C. A novel hypomorphic PDX1 mutation responsible for permanent neonatal diabetes with subclinical exocrine deficiency. Diabetes. 59: 733-40. PMID 20009086 DOI: 10.2337/Db09-1284 |
0.753 |
|
2009 |
Sachdeva MM, Claiborn KC, Khoo C, Yang J, Groff DN, Mirmira RG, Stoffers DA. Pdx1 (MODY4) regulates pancreatic beta cell susceptibility to ER stress. Proceedings of the National Academy of Sciences of the United States of America. 106: 19090-5. PMID 19855005 DOI: 10.1073/Pnas.0904849106 |
0.799 |
|
2009 |
Raab EL, Vuguin PM, Stoffers DA, Simmons RA. Neonatal exendin-4 treatment reduces oxidative stress and prevents hepatic insulin resistance in intrauterine growth-retarded rats. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 297: R1785-94. PMID 19846744 DOI: 10.1152/Ajpregu.00519.2009 |
0.388 |
|
2009 |
Oliver-Krasinski JM, Kasner MT, Yang J, Crutchlow MF, Rustgi AK, Kaestner KH, Stoffers DA. The diabetes gene Pdx1 regulates the transcriptional network of pancreatic endocrine progenitor cells in mice. The Journal of Clinical Investigation. 119: 1888-98. PMID 19487809 DOI: 10.1172/Jci37028 |
0.825 |
|
2009 |
Ham JN, Crutchlow MF, Desai BM, Simmons RA, Stoffers DA. Exendin-4 normalizes islet vascularity in intrauterine growth restricted rats: potential role of VEGF. Pediatric Research. 66: 42-6. PMID 19287346 DOI: 10.1203/Pdr.0B013E3181A282A5 |
0.415 |
|
2009 |
Sachdeva MM, Stoffers DA. Minireview: Meeting the demand for insulin: molecular mechanisms of adaptive postnatal beta-cell mass expansion. Molecular Endocrinology (Baltimore, Md.). 23: 747-58. PMID 19196831 DOI: 10.1210/Me.2008-0400 |
0.8 |
|
2008 |
Habbe N, Shi G, Meguid RA, Fendrich V, Esni F, Chen H, Feldmann G, Stoffers DA, Konieczny SF, Leach SD, Maitra A. Spontaneous induction of murine pancreatic intraepithelial neoplasia (mPanIN) by acinar cell targeting of oncogenic Kras in adult mice. Proceedings of the National Academy of Sciences of the United States of America. 105: 18913-8. PMID 19028870 DOI: 10.1073/Pnas.0810097105 |
0.386 |
|
2008 |
Claiborn KC, Stoffers DA. Toward a cell-based cure for diabetes: advances in production and transplant of beta cells. The Mount Sinai Journal of Medicine, New York. 75: 362-71. PMID 18729181 DOI: 10.1002/Msj.20058 |
0.796 |
|
2008 |
Oliver-Krasinski JM, Stoffers DA. On the origin of the beta cell. Genes & Development. 22: 1998-2021. PMID 18676806 DOI: 10.1101/Gad.1670808 |
0.807 |
|
2008 |
De León DD, Li C, Delson MI, Matschinsky FM, Stanley CA, Stoffers DA. Exendin-(9-39) corrects fasting hypoglycemia in SUR-1-/- mice by lowering cAMP in pancreatic beta-cells and inhibiting insulin secretion. The Journal of Biological Chemistry. 283: 25786-93. PMID 18635551 DOI: 10.1074/Jbc.M804372200 |
0.448 |
|
2008 |
Crutchlow MF, Yu M, Bae YS, Deng S, Stoffers DA. Exendin-4 does not promote Beta-cell proliferation or survival during the early post-islet transplant period in mice. Transplantation Proceedings. 40: 1650-7. PMID 18589167 DOI: 10.1016/J.Transproceed.2008.03.161 |
0.356 |
|
2008 |
Fendrich V, Esni F, Garay MV, Feldmann G, Habbe N, Jensen JN, Dor Y, Stoffers D, Jensen J, Leach SD, Maitra A. Hedgehog signaling is required for effective regeneration of exocrine pancreas. Gastroenterology. 135: 621-31. PMID 18515092 DOI: 10.1053/J.Gastro.2008.04.011 |
0.431 |
|
2008 |
Park JH, Stoffers DA, Nicholls RD, Simmons RA. Development of type 2 diabetes following intrauterine growth retardation in rats is associated with progressive epigenetic silencing of Pdx1. The Journal of Clinical Investigation. 118: 2316-24. PMID 18464933 DOI: 10.1172/Jci33655 |
0.435 |
|
2007 |
Crutchlow MF, Stoffers DA. Maximizing endogenous β-cell regeneration. Current Opinion in Organ Transplantation. 12: 55-62. PMID 27792090 DOI: 10.1097/Mot.0B013E328012B281 |
0.543 |
|
2007 |
Desai BM, Oliver-Krasinski J, De Leon DD, Farzad C, Hong N, Leach SD, Stoffers DA. Preexisting pancreatic acinar cells contribute to acinar cell, but not islet beta cell, regeneration. The Journal of Clinical Investigation. 117: 971-7. PMID 17404620 DOI: 10.1172/Jci29988 |
0.811 |
|
2007 |
Crutchlow MF, Stoffers DA. Maximizing endogenous β-cell regeneration Current Opinion in Organ Transplantation. 12: 55-62. DOI: 10.1097/MOT.0b013e328012b281 |
0.328 |
|
2006 |
Liu A, Oliver-Krasinski J, Stoffers DA. Two conserved domains in PCIF1 mediate interaction with pancreatic transcription factor PDX-1. Febs Letters. 580: 6701-6. PMID 17126328 DOI: 10.1016/J.Febslet.2006.11.021 |
0.772 |
|
2006 |
Deramaudt TB, Sachdeva MM, Wescott MP, Chen Y, Stoffers DA, Rustgi AK. The PDX1 homeodomain transcription factor negatively regulates the pancreatic ductal cell-specific keratin 19 promoter. The Journal of Biological Chemistry. 281: 38385-95. PMID 17056599 DOI: 10.1074/Jbc.M605891200 |
0.788 |
|
2006 |
De León DD, Farzad C, Crutchlow MF, Brestelli J, Tobias J, Kaestner KH, Stoffers DA. Identification of transcriptional targets during pancreatic growth after partial pancreatectomy and exendin-4 treatment. Physiological Genomics. 24: 133-43. PMID 16410542 DOI: 10.1152/Physiolgenomics.00156.2005 |
0.491 |
|
2006 |
Lee CS, De León DD, Kaestner KH, Stoffers DA. Regeneration of pancreatic islets after partial pancreatectomy in mice does not involve the reactivation of neurogenin-3. Diabetes. 55: 269-72. PMID 16361411 |
0.393 |
|
2006 |
De León DD, Crutchlow MF, Ham JY, Stoffers DA. Role of glucagon-like peptide-1 in the pathogenesis and treatment of diabetes mellitus. The International Journal of Biochemistry & Cell Biology. 38: 845-59. PMID 16202636 DOI: 10.1016/J.Biocel.2005.07.011 |
0.487 |
|
2006 |
Lee CS, León DDD, Kaestner KH, Stoffers DA. Regeneration of pancreatic islets after partial pancreatectomy in mice does not involve the reactivation of neurogenin-3. Diabetes. 55: 269-272. DOI: 10.2337/Diabetes.55.02.06.Db05-1300 |
0.533 |
|
2005 |
Means AL, Meszoely IM, Suzuki K, Miyamoto Y, Rustgi AK, Coffey RJ, Wright CV, Stoffers DA, Leach SD. Pancreatic epithelial plasticity mediated by acinar cell transdifferentiation and generation of nestin-positive intermediates. Development (Cambridge, England). 132: 3767-76. PMID 16020518 DOI: 10.1242/Dev.01925 |
0.442 |
|
2004 |
Stoffers DA. The development of beta-cell mass: recent progress and potential role of GLP-1. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Mã©Tabolisme. 36: 811-21. PMID 15655713 DOI: 10.1055/S-2004-826168 |
0.453 |
|
2004 |
Liu A, Desai BM, Stoffers DA. Identification of PCIF1, a POZ domain protein that inhibits PDX-1 (MODY4) transcriptional activity. Molecular and Cellular Biology. 24: 4372-83. PMID 15121856 DOI: 10.1128/Mcb.24.10.4372-4383.2004 |
0.546 |
|
2004 |
Heller RS, Stoffers DA, Liu A, Schedl A, Crenshaw EB, Madsen OD, Serup P. The role of Brn4/Pou3f4 and Pax6 in forming the pancreatic glucagon cell identity. Developmental Biology. 268: 123-34. PMID 15031110 DOI: 10.1016/J.Ydbio.2003.12.008 |
0.526 |
|
2004 |
Esni F, Stoffers DA, Takeuchi T, Leach SD. Origin of exocrine pancreatic cells from nestin-positive precursors in developing mouse pancreas. Mechanisms of Development. 121: 15-25. PMID 14706696 DOI: 10.1016/J.Mod.2003.08.010 |
0.455 |
|
2003 |
Stoffers DA, Desai BM, DeLeon DD, Simmons RA. Neonatal exendin-4 prevents the development of diabetes in the intrauterine growth retarded rat. Diabetes. 52: 734-40. PMID 12606515 DOI: 10.2337/Diabetes.52.3.734 |
0.432 |
|
2003 |
De León DD, Deng S, Madani R, Ahima RS, Drucker DJ, Stoffers DA. Role of endogenous glucagon-like peptide-1 in islet regeneration after partial pancreatectomy. Diabetes. 52: 365-71. PMID 12540609 DOI: 10.2337/Diabetes.52.2.365 |
0.438 |
|
2002 |
Lee CS, Sund NJ, Vatamaniuk MZ, Matschinsky FM, Stoffers DA, Kaestner KH. Foxa2 controls Pdx1 gene expression in pancreatic beta-cells in vivo. Diabetes. 51: 2546-51. PMID 12145169 DOI: 10.2337/Diabetes.51.8.2546 |
0.541 |
|
2001 |
Sund NJ, Vatamaniuk MZ, Casey M, Ang SL, Magnuson MA, Stoffers DA, Matschinsky FM, Kaestner KH. Tissue-specific deletion of Foxa2 in pancreatic beta cells results in hyperinsulinemic hypoglycemia. Genes & Development. 15: 1706-15. PMID 11445544 DOI: 10.1101/Gad.901601 |
0.502 |
|
2001 |
Heller RS, Stoffers DA, Bock T, Svenstrup K, Jensen J, Horn T, Miller CP, Habener JF, Madsen OD, Serup P. Improved glucose tolerance and acinar dysmorphogenesis by targeted expression of transcription factor PDX-1 to the exocrine pancreas. Diabetes. 50: 1553-61. PMID 11423476 DOI: 10.2337/Diabetes.50.7.1553 |
0.689 |
|
2000 |
Clocquet AR, Egan JM, Stoffers DA, Muller DC, Wideman L, Chin GA, Clarke WL, Hanks JB, Habener JF, Elahi D. Impaired insulin secretion and increased insulin sensitivity in familial maturity-onset diabetes of the young 4 (insulin promoter factor 1 gene). Diabetes. 49: 1856-64. PMID 11078452 DOI: 10.2337/Diabetes.49.11.1856 |
0.6 |
|
2000 |
Stoffers DA, Kieffer TJ, Hussain MA, Drucker DJ, Bonner-Weir S, Habener JF, Egan JM. Insulinotropic glucagon-like peptide 1 agonists stimulate expression of homeodomain protein IDX-1 and increase islet size in mouse pancreas. Diabetes. 49: 741-8. PMID 10905482 DOI: 10.2337/Diabetes.49.5.741 |
0.676 |
|
1999 |
Stoffers DA, Heller RS, Miller CP, Habener JF. Developmental Expression of the Homeodomain Protein IDX-1 in Mice Transgenic for an IDX-1 Promoter/lacZ Transcriptional Reporter1. Endocrinology. 140: 5374-5381. PMID 28204265 DOI: 10.1210/endo.140.11.7122 |
0.478 |
|
1999 |
Melander A, Olsson J, Lindberg G, Salzman A, Howard T, Stang P, Lydick E, Emslie-Smith A, Boyle DI, Evans JM, Macdonald TM, Bain J, Sullivan F, Juhl C, ... ... Stoffers DA, ... ... Stoffers D, et al. 35th Annual Meeting of the European Association for the Study of Diabetes : Brussels, Belgium, 28 September-2 October 1999. Diabetologia. 42: A1-A330. PMID 27770183 DOI: 10.1007/Bf03375458 |
0.517 |
|
1999 |
Xu G, Stoffers DA, Habener JF, Bonner-Weir S. Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats. Diabetes. 48: 2270-6. PMID 10580413 DOI: 10.2337/Diabetes.48.12.2270 |
0.639 |
|
1999 |
Hani EH, Stoffers DA, Chèvre JC, Durand E, Stanojevic V, Dina C, Habener JF, Froguel P. Defective mutations in the insulin promoter factor-1 (IPF-1) gene in late-onset type 2 diabetes mellitus. The Journal of Clinical Investigation. 104: R41-8. PMID 10545531 DOI: 10.1172/Jci7469 |
0.636 |
|
1999 |
Stoffers DA, Heller RS, Miller CP, Habener JF. Developmental expression of the homeodomain protein IDX-1 in mice transgenic for an IDX-1 promoter/lacZ transcriptional reporter. Endocrinology. 140: 5374-81. PMID 10537169 DOI: 10.1210/Endo.140.11.7122 |
0.576 |
|
1998 |
Heller RS, Stoffers DA, Hussain MA, Miller CP, Habener JF. Misexpression of the pancreatic homeodomain protein IDX-1 by the Hoxa-4 promoter associated with agenesis of the cecum. Gastroenterology. 115: 381-7. PMID 9679043 DOI: 10.1016/S0016-5085(98)70204-5 |
0.6 |
|
1998 |
Stoffers DA, Stanojevic V, Habener JF. Insulin promoter factor-1 gene mutation linked to early-onset type 2 diabetes mellitus directs expression of a dominant negative isoprotein. The Journal of Clinical Investigation. 102: 232-41. PMID 9649577 DOI: 10.1172/Jci2242 |
0.646 |
|
1998 |
Chèvre JC, Hani EH, Stoffers DA, Habener JF, Froguel P. Insulin promoter factor 1 gene is not a major cause of maturity-onset diabetes of the young in French Caucasians. Diabetes. 47: 843-4. PMID 9588460 DOI: 10.2337/Diabetes.47.5.843 |
0.509 |
|
1997 |
Stoffers DA, Thomas MK, Habener JF. Homeodomain protein IDX-1: a master regulator of pancreas development and insulin gene expression. Trends in Endocrinology and Metabolism: Tem. 8: 145-51. PMID 18406800 DOI: 10.1016/S1043-2760(97)00008-8 |
0.682 |
|
1997 |
Stoffers DA, Ferrer J, Clarke WL, Habener JF. Early-onset type-II diabetes mellitus (MODY4) linked to IPF1. Nature Genetics. 17: 138-9. PMID 9326926 DOI: 10.1038/Ng1097-138 |
0.522 |
|
1997 |
Stoffers DA, Zinkin NT, Stanojevic V, Clarke WL, Habener JF. Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence. Nature Genetics. 15: 106-10. PMID 8988180 DOI: 10.1038/Ng0197-106 |
0.609 |
|
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