Vincent W. Yang - Publications

Affiliations: 
Biological and Biomedical Sciences Emory University, Atlanta, GA 
Area:
Cell Biology, Oncology, Genetics

176 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Katano T, Bialkowska AB, Yang VW. KLF4 Regulates Goblet Cell Differentiation in BMI1 Reserve Intestinal Stem Cell Lineage during Homeostasis. International Journal of Stem Cells. PMID 32840226 DOI: 10.15283/Ijsc20048  0.39
2020 Hoffman M, Kyriazis ID, Lyons W, Rajan S, Gao E, Khan M, Bannister T, Yang V, Bialkowska A, Selzman CH, Drakos SH, Drosatos K. Cardiomyocyte Krüppel‐like Factor 5 Regulates Ceramide Biosynthesis and miR‐30 Suppression in Ischemic Cardiomyopathy and Promotes Systolic Dysfunction The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.07226  0.329
2020 Katano T, Orzechowska EJ, Bialkowska AB, Yang VW. Su1106 KRÜPPEL-LIKE FACTOR 4 MODULATES GOBLET CELL DIFFERENTIATION AND PLAYS A RADIO-PROTECTIVE ROLE IN THE BMI1+ INTESTINAL RESERVE STEM CELL LINEAGE Gastroenterology. 158: S-510. DOI: 10.1016/S0016-5085(20)31958-2  0.362
2020 Orzechowska EJ, Katano T, Bialkowska AB, Yang VW. 827 STROMAL CELLS STIMULATE BMI1-DEPENDENT SMALL INTESTINAL EPITHELIAL REGENERATION AFTER γ RADIATION-INDUCED INJURY VIA WNT SIGNALLING-TRIGGERED MSI1 INDUCTION Gastroenterology. 158: S-163. DOI: 10.1016/S0016-5085(20)31097-0  0.306
2020 Shieh J, Chu TH, Liu Y, Kim JM, de Sabando AR, Sheridan B, Bialkowska AB, Yang VW. 641 DISRUPTION OF INTESTINAL EPITHELIUM DUE TO DELETION OF KRÜPPEL-LIKE FACTOR 5 RESEMBLES THE INFLAMMATORY RESPONSE IN INFLAMMATORY BOWEL DISEASE Gastroenterology. 158: S-138. DOI: 10.1016/S0016-5085(20)31027-1  0.3
2019 Agbo KC, Huang JZ, Ghaleb AM, Williams JL, Shroyer KR, Bialkowska AB, Yang VW. Loss of the Krüppel-like factor 4 tumor suppressor is associated with epithelial-mesenchymal transition in colorectal cancer. Journal of Cancer Metastasis and Treatment. 5. PMID 32566755 DOI: 10.20517/2394-4722.2019.35  0.383
2019 Kim CK, Saxena M, Maharjan K, Song JJ, Shroyer KR, Bialkowska AB, Shivdasani RA, Yang VW. Krüppel-like factor 5 regulates stemness, lineage specification, and regeneration of intestinal epithelial stem cells. Cellular and Molecular Gastroenterology and Hepatology. PMID 31778829 DOI: 10.1016/J.Jcmgh.2019.11.009  0.408
2019 Kim J, Wang C, Ruiz de Sabando A, Cole HL, Huang TJ, Yang J, Bannister TD, Yang VW, Bialkowska AB. The novel small molecule SR18662 efficiently inhibits the growth of colorectal cancer in vitro and in vivo. Molecular Cancer Therapeutics. PMID 31358661 DOI: 10.1158/1535-7163.Mct-18-1366  0.399
2019 Wang D, Bi Y, Hu L, Luo Y, Ji J, Mao AZ, Logsdon CD, Li E, Abbruzzese JL, Li Z, Yang VW, Lu W. Obesogenic high-fat diet heightens aerobic glycolysis through hyperactivation of oncogenic KRAS. Cell Communication and Signaling : Ccs. 17: 19. PMID 30819189 DOI: 10.1186/S12964-019-0333-7  0.303
2019 Shieh J, Liu Y, Kim JM, de Sabando AR, Bialkowska AB, Yang VW. Su1946 – Disruption of Intestinal Epithelium with the Deletion of KrüPpel-Like Factor 5 (KLF5) Resembles the Inflammatory Response in Human Inflammatory Bowel Disease Gastroenterology. 156: S-669. DOI: 10.1016/S0016-5085(19)38580-4  0.309
2019 Kim CK, Maharjan K, Bialkowska AB, Yang VW. Sa1101 – KrüPpel-Like Factor 5 is Critical for Intestinal Stem Cell Functions and Identity During Self-Renewal and Regeneration Post-Injury Gastroenterology. 156: S-271. DOI: 10.1016/S0016-5085(19)37484-0  0.322
2019 Katano T, Kim CK, Orzechowska EJ, Bialkowska AB, Yang VW. Sa1100 – KrüPpel-Like Factor 4 Regulates Bmi1+ Intestinal Reserve Stem Cells During Homeostasis and Injury Gastroenterology. 156: S-270-S-271. DOI: 10.1016/S0016-5085(19)37483-9  0.347
2019 Orzechowska EJ, Sherpa P, Bialkowska AB, Yang VW. 774 – Role of Cell Cycle Inhibitor P21WAF1/CIP1, RNA Binding Protein Musashi-1, and KrüPPEL-Like Factor 4 in Regulation of Mouse Bmi1+ Reserve Intestinal Stem Cells Function After γ Radiation-Induced Injury In Vivo Gastroenterology. 156: S-158-S-159. DOI: 10.1016/S0016-5085(19)37190-2  0.371
2018 Kim CK, Yang VW, Bialkowska AB. Correction to: The Role of Intestinal Stem Cells in Epithelial Regeneration Following Radiation-Induced Gut Injury. Current Stem Cell Reports. 4: 95. PMID 31329798 DOI: 10.1007/S40778-018-0121-0  0.305
2018 Yang VW, Liu Y, Kim J, Shroyer KR, Bialkowska AB. Increased genetic instability and accelerated progression of colitis-associated colorectal cancer through intestinal epithelium-specific deletion of Klf4. Molecular Cancer Research : McR. PMID 30108164 DOI: 10.1158/1541-7786.Mcr-18-0399  0.407
2018 Estrada CC, Paladugu P, Guo Y, Pace J, Revelo MP, Salant DJ, Shankland SJ, D'Agati VD, Mehrotra A, Cardona S, Bialkowska AB, Yang VW, He JC, Mallipattu SK. Krüppel-like factor 4 is a negative regulator of STAT3-induced glomerular epithelial cell proliferation. Jci Insight. 3. PMID 29925693 DOI: 10.1172/Jci.Insight.98214  0.36
2018 He P, Yang JW, Yang VW, Bialkowska AB. Tu1358 - KrÜPpel-Like Factor 5 Mediates Pancreatitis-Induced Adm by Regulating Ndrg2 and Stat3 Signaling Gastroenterology. 154: S-942-S-943. DOI: 10.1016/S0016-5085(18)33174-3  0.327
2018 Orzechowska EJ, Parajuli S, Bialkowska AB, Yang VW. Mo1065 - P21 Waf1/Cip1 and RNA Binding Protein Musashi-1 Regulate small Intestinal Epithelium Regeneration after Γ Radiation-Induced Injury by Activation of the Subpopulation of Reserve Intestinal Stem Cells In Vivo Gastroenterology. 154: S-688. DOI: 10.1016/S0016-5085(18)32426-0  0.339
2018 Liu Y, Kim JM, de Sabando AR, Bialkowska AB, Yang VW. 1016 - Mice with Intestine-Specific Deletion of KRÜPPEL-Like Factor 5 Exhibit an Inflammatory Phenotype Gastroenterology. 154: S-192. DOI: 10.1016/S0016-5085(18)31048-5  0.35
2018 Kim CK, Maharjan K, Bialkowska AB, Yang VW. 596 - KRÜPPEL-Like Factor 5 is Critical for Intestinal Stem Cell Functions During Self-Renewal and Tissue Regeneration Post-Irradiation Injury Gastroenterology. 154: S-126-S-127. DOI: 10.1016/S0016-5085(18)30849-7  0.323
2017 Kim CK, Yang VW, Bialkowska AB. The Role of Intestinal Stem Cells in Epithelial Regeneration Following Radiation-Induced Gut Injury. Current Stem Cell Reports. 3: 320-332. PMID 29497599 DOI: 10.1007/S40778-017-0103-7  0.318
2017 He P, Yang JW, Yang VW, Bialkowska AB. Krüppel-like Factor 5, Increased in Pancreatic Ductal Adenocarcinoma, Promotes Proliferation, Acinar to Ductal Metaplasia, Pancreatic Intraepithelial Neoplasia, and Tumor Growth in Mice. Gastroenterology. PMID 29248441 DOI: 10.1053/J.Gastro.2017.12.005  0.361
2017 Liu Y, Chidgey M, Yang VW, Bialkowska AB. Krüppel-like factor 5 is essential for maintenance of barrier function in mouse colon. American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00172.2017. PMID 28864500 DOI: 10.1152/Ajpgi.00172.2017  0.424
2017 Fujikawa J, Takeuchi Y, Kanazawa S, Nomir AG, Kito A, Elkhashab E, Ghaleb AM, Yang VW, Akiyama S, Morisaki I, Yamashiro T, Wakisaka S, Abe M. Kruppel-like factor 4 regulates matrix metalloproteinase and aggrecanase gene expression in chondrocytes. Cell and Tissue Research. PMID 28856432 DOI: 10.1007/S00441-017-2674-0  0.359
2017 Gu X, Mallipattu SK, Guo Y, Revelo MP, Pace J, Miller T, Gao X, Jain MK, Bialkowska AB, Yang VW, He JC, Mei C. The loss of Krüppel-like factor 15 in Foxd1(+) stromal cells exacerbates kidney fibrosis. Kidney International. PMID 28651950 DOI: 10.1016/J.Kint.2017.03.037  0.335
2017 Lee CW, Huang WC, Huang HD, Huang YH, Ho JH, Yang MH, Yang VW, Lee OK. DNA Methyltransferases Modulate Hepatogenic Lineage Plasticity of Mesenchymal Stromal Cells. Stem Cell Reports. PMID 28602611 DOI: 10.1016/J.Stemcr.2017.05.008  0.319
2017 Kim CK, He P, Bialkowska AB, Yang VW. SP and KLF Transcription Factors in Digestive Physiology and Diseases. Gastroenterology. PMID 28366734 DOI: 10.1053/J.Gastro.2017.03.035  0.364
2017 Bialkowska AB, Yang VW, Mallipattu SK. Krüppel-like factors in mammalian stem cells and development. Development (Cambridge, England). 144: 737-754. PMID 28246209 DOI: 10.1242/Dev.145441  0.38
2017 Ghaleb AM, Yang VW. Krüppel-like factor 4 (KLF4): What we currently know. Gene. PMID 28237823 DOI: 10.1016/J.Gene.2017.02.025  0.38
2016 Walter L, Pujada A, Bhatnagar N, Bialkowska AB, Yang VW, Laroui H, Garg P. Epithelial derived-matrix metalloproteinase (MMP9) exhibits a novel defensive role of tumor suppressor in colitis associated cancer by activating MMP9-Notch1-ARF-p53 axis. Oncotarget. PMID 27861153 DOI: 10.18632/Oncotarget.13406  0.32
2016 Kim CK, Bialkowska AB, Yang VW. Intestinal stem cell resurgence by enterocyte precursors. Stem Cell Investigation. 3: 49. PMID 27777938 DOI: 10.21037/Sci.2016.09.01  0.351
2016 García-Barros M, Coant N, Kawamori T, Wada M, Snider AJ, Truman JP, Wu BX, Furuya H, Clarke CJ, Bialkowska AB, Ghaleb A, Yang VW, Obeid LM, Hannun YA. Role of neutral ceramidase in colon cancer. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 27609772 DOI: 10.1096/Fj.201600611R  0.366
2016 Mallipattu SK, Guo Y, Revelo MP, Roa-Peña L, Miller T, Ling J, Shankland SJ, Bialkowska AB, Ly V, Estrada C, Jain MK, Lu Y, Ma'ayan A, Mehrotra A, Yacoub R, ... ... Yang VW, et al. Krüppel-Like Factor 15 Mediates Glucocorticoid-Induced Restoration of Podocyte Differentiation Markers. Journal of the American Society of Nephrology : Jasn. PMID 27288011 DOI: 10.1681/Asn.2015060672  0.383
2016 Kuruvilla JG, Kim CK, Ghaleb AM, Bialkowska AB, Kuo CJ, Yang VW. Krüppel-like Factor 4 Modulates Development of BMI1(+) Intestinal Stem Cell-Derived Lineage Following γ-Radiation-Induced Gut Injury in Mice. Stem Cell Reports. PMID 27237377 DOI: 10.1016/J.Stemcr.2016.04.014  0.354
2016 Snider AJ, Bialkowska AB, Ghaleb AM, Yang VW, Obeid LM, Hannun YA. Murine Model for Colitis-Associated Cancer of the Colon. Methods in Molecular Biology (Clifton, N.J.). 1438: 245-54. PMID 27150094 DOI: 10.1007/978-1-4939-3661-8_14  0.343
2016 Wang K, Xu R, Snider AJ, Schrandt J, Li Y, Bialkowska AB, Li M, Zhou J, Hannun YA, Obeid LM, Yang VW, Mao C. Alkaline ceramidase 3 deficiency aggravates colitis and colitis-associated tumorigenesis in mice by hyperactivating the innate immune system. Cell Death & Disease. 7: e2124. PMID 26938296 DOI: 10.1038/Cddis.2016.36  0.324
2016 Ghaleb AM, Elkarim EA, Bialkowska AB, Yang VW. KLF4 Suppresses Tumor Formation in Genetic and Pharmacological Mouse Models of Colonic Tumorigenesis. Molecular Cancer Research : McR. 14: 385-96. PMID 26839262 DOI: 10.1158/1541-7786.Mcr-15-0410  0.373
2016 Walter L, Pujada A, Mohammadian S, Bialkowska A, Yang V, Garg P. Abstract 3670: Matrix metalloproteinase 9 has a novel tumor suppressive role in inflammation associated colorectal cancer by modulating intrinsic tumor microenvironment Cancer Research. 76: 3670-3670. DOI: 10.1158/1538-7445.Am2016-3670  0.368
2016 Kim CK, Kuruvilla JG, Ghaleb A, Bialkowska A, Yang VW. Tu1410 Krüppel-Like Factor 5 Regulates the Regeneration of the Intestinal Epithelium Post-Irradiation Injury Gastroenterology. 150: S897-S898. DOI: 10.1016/S0016-5085(16)33034-7  0.328
2016 de Sabando AR, Bialkowska A, Kim J, Yang VW. Su1191 Inducible Deletion of Krüppel-Like Factor 5 (KLF5) From the Intestinal Epithelium Sensitizes Mice to Dextran Sulfate Sodium Treatment Gastroenterology. 150: S491. DOI: 10.1016/S0016-5085(16)31690-0  0.348
2016 Liu Y, Chidgey M, Yang VW, Bialkowska A. Sa1417 Krüppel-Like Factor 5 Modulates Intestinal Epithelial Barrier Function by Regulating Components of Desmosomes Gastroenterology. 150: S309-S310. DOI: 10.1016/S0016-5085(16)31086-1  0.342
2016 Ghaleb A, Elkarim E, Bialkowska A, Yang VW. 675 Krüppel-Like Factor 4 Suppresses Intestinal Tumorigenesis by Regulating mTOR Signaling Pathway and DNA Repair Mechanisms Gastroenterology. 150: S138-S139. DOI: 10.1016/S0016-5085(16)30566-2  0.333
2016 He P, Yang VW, Bialkowska A. 558 Krüppel-Like Factor 5 Mediates Cell Proliferation in Mouse Models of Pancreatic Ductal Adenocarcinoma Gastroenterology. 150: S118. DOI: 10.1016/S0016-5085(16)30503-0  0.377
2015 Ruiz de Sabando A, Wang C, He Y, García-Barros M, Kim J, Shroyer KR, Bannister TD, Yang VW, Bialkowska AB. ML264 - a novel small-molecule compound that potently inhibits growth of colorectal cancer. Molecular Cancer Therapeutics. PMID 26621868 DOI: 10.1158/1535-7163.Mct-15-0600  0.396
2015 Kuruvilla JG, Ghaleb AM, Bialkowska AB, Nandan MO, Yang VW. Role of Krüppel-like factor 5 in the maintenance of the stem cell niche in the intestinal crypt. Stem Cell and Translational Investigation. 2. PMID 26097895 DOI: 10.14800/Scti.839  0.426
2015 Ghaleb AM, Bialkowska AB, Snider AJ, Gnatenko DV, Hannun YA, Yang VW, Schmidt VA. IQ Motif-Containing GTPase-Activating Protein 2 (IQGAP2) Is a Novel Regulator of Colonic Inflammation in Mice. Plos One. 10: e0129314. PMID 26047140 DOI: 10.1371/Journal.Pone.0129314  0.363
2015 Mallipattu SK, Horne SJ, D'Agati V, Narla G, Liu R, Frohman MA, Dickman K, Chen EY, Ma'ayan A, Bialkowska AB, Ghaleb AM, Nandan MO, Jain MK, Daehn I, Chuang PY, ... Yang VW, et al. Krüppel-like factor 6 regulates mitochondrial function in the kidney. The Journal of Clinical Investigation. 125: 1347-61. PMID 25689250 DOI: 10.1172/Jci77084  0.328
2015 Nandan MO, Ghaleb AM, Bialkowska AB, Yang VW. Krüppel-like factor 5 is essential for proliferation and survival of mouse intestinal epithelial stem cells. Stem Cell Research. 14: 10-9. PMID 25460247 DOI: 10.1016/J.Scr.2014.10.008  0.411
2015 Talmasov D, Xinjun Z, Yu B, Nandan MO, Bialkowska AB, Elkarim E, Kuruvilla J, Yang VW, Ghaleb AM. Krüppel-like factor 4 is a radioprotective factor for the intestine following γ-radiation-induced gut injury in mice. American Journal of Physiology. Gastrointestinal and Liver Physiology. 308: G121-38. PMID 25414097 DOI: 10.1152/Ajpgi.00080.2014  0.363
2015 de Sabando AR, Bannister TD, Wang C, He Y, Yang VW, Bialkowska A. Tu1974 Ml264: A Small-Molecule Compound That Inhibits Proliferation of Colorectal Cancer Cells by Selectively Targeting Krüppel-Like Factor 5 (KLF5) Gastroenterology. 148: S-950. DOI: 10.1016/S0016-5085(15)33241-8  0.342
2015 Liu Y, Yang VW, Bialkowska A. Tu1375 Krüppel-Like Factor 5 (KLF5) Regulates Intestinal Barrier Function Gastroenterology. 148: S-873. DOI: 10.1016/S0016-5085(15)32962-0  0.358
2015 Bialkowska A, Hultine S, Yang VW. 400 Krüppel-Like Factor 5 (KLF5) Regulates Epidermal Growth Factor Receptor-(EGFR) Mediated Wound Healing in Intestinal Epithelial Cells Gastroenterology. 148: S-85. DOI: 10.1016/S0016-5085(15)30294-8  0.346
2015 Kuruvilla JG, Bialkowska A, Ghaleb A, Yang VW. 67 Krüppel-Like Factor 4 Modulates the Proliferation and Survival of Bmi1+ Stem Cell Derived Crypts in the Intestine Following γ-Radiation-Induced Gut Injury in Mice Gastroenterology. 148: S-19. DOI: 10.1016/S0016-5085(15)30067-6  0.352
2014 Snider AJ, Ali WH, Sticca JA, Coant N, Ghaleb AM, Kawamori T, Yang VW, Hannun YA, Obeid LM. Distinct roles for hematopoietic and extra-hematopoietic sphingosine kinase-1 in inflammatory bowel disease. Plos One. 9: e113998. PMID 25460165 DOI: 10.1371/Journal.Pone.0113998  0.332
2014 Ghaleb AM, Laroui H, Merlin D, Yang VW. Genetic deletion of Klf4 in the mouse intestinal epithelium ameliorates dextran sodium sulfate-induced colitis by modulating the NF-κB pathway inflammatory response. Inflammatory Bowel Diseases. 20: 811-20. PMID 24681655 DOI: 10.1097/Mib.0000000000000022  0.432
2014 Nandan MO, Ghaleb AM, Liu Y, Bialkowska AB, McConnell BB, Shroyer KR, Robine S, Yang VW. Inducible intestine-specific deletion of Krüppel-like factor 5 is characterized by a regenerative response in adult mouse colon. Developmental Biology. 387: 191-202. PMID 24440658 DOI: 10.1016/J.Ydbio.2014.01.002  0.425
2014 Bialkowska AB, Liu Y, Nandan MO, Yang VW. A colon cancer-derived mutant of Krüppel-like factor 5 (KLF5) is resistant to degradation by glycogen synthase kinase 3β (GSK3β) and the E3 ubiquitin ligase F-box and WD repeat domain-containing 7α (FBW7α). The Journal of Biological Chemistry. 289: 5997-6005. PMID 24398687 DOI: 10.1074/Jbc.M113.508549  0.388
2014 Ghaleb A, Yang VW. Tu1660 Intestine-Specific Deletion of KLF4 Renders Mice Susceptible to Inflammation-Associated Tumorigenesis and Increases Intestinal Adenoma Multiplicity and Colonic Adenoma Incidence in APCMIN/+ Mice Gastroenterology. 146: S-812. DOI: 10.1016/S0016-5085(14)62936-X  0.32
2014 Liu Y, Bialkowska A, Yang VW. Su1869 Kr¨Ppel-Like Factor 5 Modulates Intestinal Epithelial Barrier Function by Regulating Components of the Tight Junction In Vitro Gastroenterology. 146: S-490. DOI: 10.1016/S0016-5085(14)61759-5  0.342
2014 Nandan MO, Ghaleb A, Bialkowska A, Yang VW. 204 Intestinal Stem Cell (LGR5)-Specific Deletion of Krüppel-Like Factor 5 in Mice Results in Acute Loss of Proliferation and Chronic Depletion of Stem Cells Gastroenterology. 146: S-53. DOI: 10.1016/S0016-5085(14)60187-6  0.36
2013 Liu L, Souto J, Liao W, Jiang Y, Li Y, Nishinakamura R, Huang S, Rosengart T, Yang VW, Schuster M, Ma Y, Yang J. Histone lysine-specific demethylase 1 (LSD1) protein is involved in Sal-like protein 4 (SALL4)-mediated transcriptional repression in hematopoietic stem cells. The Journal of Biological Chemistry. 288: 34719-28. PMID 24163373 DOI: 10.1074/Jbc.M113.506568  0.375
2013 El-Karim EA, Hagos EG, Ghaleb AM, Yu B, Yang VW. Krüppel-like factor 4 regulates genetic stability in mouse embryonic fibroblasts. Molecular Cancer. 12: 89. PMID 23919723 DOI: 10.1186/1476-4598-12-89  0.45
2013 Lee SJ, No YR, Dang DT, Dang LH, Yang VW, Shim H, Yun CC. Regulation of hypoxia-inducible factor 1α (HIF-1α) by lysophosphatidic acid is dependent on interplay between p53 and Krüppel-like factor 5. The Journal of Biological Chemistry. 288: 25244-53. PMID 23880760 DOI: 10.1074/Jbc.M113.489708  0.357
2013 Noto JM, Khizanishvili T, Chaturvedi R, Piazuelo MB, Romero-Gallo J, Delgado AG, Khurana SS, Sierra JC, Krishna US, Suarez G, Powell AE, Goldenring JR, Coffey RJ, Yang VW, Correa P, et al. Helicobacter pylori promotes the expression of Krüppel-like factor 5, a mediator of carcinogenesis, in vitro and in vivo. Plos One. 8: e54344. PMID 23372710 DOI: 10.1371/Journal.Pone.0054344  0.318
2013 Ghaleb A, Laroui H, Rakhya P, Merlin D, Yang VW. Tu1624 Amelioration of Dextran Sodium Sulfate-Induced Colitis in Mice by Genetic Deletion of KLF4 in the Intestinal Epithelium or by Oral Delivery of Nanoparticles Loaded With KLF4-SiRNA to the Colonic Epithelial Cells Gastroenterology. 144: S-808-S-809. DOI: 10.1016/S0016-5085(13)62993-5  0.325
2013 Bialkowska A, Liu Y, Nandan MO, Yang VW. Sa1678 A Colon Cancer-Derived Mutant of KrüPpel-Like Factor 5 Inhibits Its Degradation by Glycogen Synthase Kinase 3β and the E3 Ubiquitin Ligase FBW7 Gastroenterology. 144: S-281. DOI: 10.1016/S0016-5085(13)60991-9  0.316
2013 Elkarim E, Ghaleb A, Hagos E, Yang VW. 681 KrüPpel-Like Factor 4 Is Necessary and Sufficient for Re-Establishing Genetic Stability in Mouse Embryonic Fibroblasts Null for KLF4 Gastroenterology. 144: S-124-S-125. DOI: 10.1016/S0016-5085(13)60448-5  0.313
2013 Talmasov D, Ghaleb A, Yu B, Nandan MO, Yang VW. 229 KrüPpel-Like Factor 4 Is a Radio-Protective Factor of the Intestine Following γ Radiation-Induced Gut Injury in Mice Gastroenterology. 144: S-50. DOI: 10.1016/S0016-5085(13)60175-4  0.332
2012 Yu B, Dalton WB, Yang VW. CDK1 regulates mediator of DNA damage checkpoint 1 during mitotic DNA damage. Cancer Research. 72: 5448-53. PMID 22962268 DOI: 10.1158/0008-5472.Can-12-2354  0.61
2012 Bialkowska AB, Yang VW. High-throughput screening strategies for targeted identification of therapeutic compounds in colorectal cancer. Future Oncology (London, England). 8: 259-72. PMID 22409463 DOI: 10.2217/Fon.12.19  0.302
2012 Chen M, Huang SL, Zhang XQ, Zhang B, Zhu H, Yang VW, Zou XP. Reversal effects of pantoprazole on multidrug resistance in human gastric adenocarcinoma cells by down-regulating the V-ATPases/mTOR/HIF-1α/P-gp and MRP1 signaling pathway in vitro and in vivo. Journal of Cellular Biochemistry. 113: 2474-87. PMID 22396185 DOI: 10.1002/Jcb.24122  0.318
2012 Chen YF, Tseng CY, Wang HW, Kuo HC, Yang VW, Lee OK. Rapid generation of mature hepatocyte-like cells from human induced pluripotent stem cells by an efficient three-step protocol. Hepatology (Baltimore, Md.). 55: 1193-203. PMID 22095466 DOI: 10.1002/Hep.24790  0.338
2012 Engda H, Yang VW, Yu B. Abstract 2028: Krüppel-like factor 4 null mouse embryonic fibroblasts exhibit DNA repair defects post exposure to gamma-irradiation Cancer Research. 72: 2028-2028. DOI: 10.1158/1538-7445.Am2012-2028  0.405
2012 Ghaleb A, Laroui H, Merlin D, Yang VW. Mo1805 Deletion of the KrüPpel-Like Factor 4 Gene in Colonic Epithelium Protects Mice From Dextran Sulfate Sodium (DSS)-Induced Colitis Gastroenterology. 142: S-689. DOI: 10.1016/S0016-5085(12)62658-4  0.352
2012 Khizanishvili T, Noto JM, Piazuelo MB, Delgado AG, Yang VW, Correa P, Peek RM. 236 Helicobacter pylori Promotes Expression of a Mediator of Carcinogenesis, KrüPpel-Like Factor 5, In Vitro and In Vivo Gastroenterology. 142: S-58. DOI: 10.1016/S0016-5085(12)60225-X  0.35
2012 Nandan MO, Yu K, Bialkowska A, McConnell B, Yang VW. 157 Intestine-Specific Deletion of KrüPpel-Like Factor 5 Results in an Epithelial Regenerative Phenotype Gastroenterology. 142: S-38. DOI: 10.1016/S0016-5085(12)60146-2  0.383
2011 Du JX, Hagos EG, Nandan MO, Bialkowska AB, Yu B, Yang VW. The E3 ubiquitin ligase SMAD ubiquitination regulatory factor 2 negatively regulates Krüppel-like factor 5 protein. The Journal of Biological Chemistry. 286: 40354-64. PMID 21953463 DOI: 10.1074/Jbc.M111.258707  0.353
2011 Bialkowska AB, Crisp M, Bannister T, He Y, Chowdhury S, Schur̈er S, Chase P, Spicer T, Madoux F, Tian C, Hodder P, Zaharevitz D, Yang VW. Identification of small-molecule inhibitors of the colorectal cancer oncogene Krüppel-like factor 5 expression by ultrahigh-throughput screening Molecular Cancer Therapeutics. 10: 2043-2051. PMID 21885866 DOI: 10.1158/1535-7163.Mct-11-0550  0.394
2011 McConnell BB, Kim SS, Yu K, Ghaleb AM, Takeda N, Manabe I, Nusrat A, Nagai R, Yang VW. Krüppel-like factor 5 is important for maintenance of crypt architecture and barrier function in mouse intestine. Gastroenterology. 141: 1302-13, 1313.e1-6. PMID 21763241 DOI: 10.1053/J.Gastro.2011.06.086  0.433
2011 Garg P, Jeppsson S, Dalmasso G, Ghaleb AM, McConnell BB, Yang VW, Gewirtz AT, Merlin D, Sitaraman SV. Notch1 regulates the effects of matrix metalloproteinase-9 on colitis-associated cancer in mice. Gastroenterology. 141: 1381-92. PMID 21723221 DOI: 10.1053/J.Gastro.2011.06.056  0.369
2011 McConnell BB, Kim SS, Bialkowska AB, Yu K, Sitaraman SV, Yang VW. Krüppel-like factor 5 protects against dextran sulfate sodium-induced colonic injury in mice by promoting epithelial repair. Gastroenterology. 140: 540-549.e2. PMID 21078320 DOI: 10.1053/J.Gastro.2010.10.061  0.415
2011 Ghaleb AM, McConnell BB, Kaestner KH, Yang VW. Altered intestinal epithelial homeostasis in mice with intestine-specific deletion of the Krüppel-like factor 4 gene. Developmental Biology. 349: 310-20. PMID 21070761 DOI: 10.1016/J.Ydbio.2010.11.001  0.434
2011 Karna P, Rida PC, Pannu V, Gupta KK, Dalton WB, Joshi H, Yang VW, Zhou J, Aneja R. A novel microtubule-modulating noscapinoid triggers apoptosis by inducing spindle multipolarity via centrosome amplification and declustering. Cell Death and Differentiation. 18: 632-44. PMID 21052096 DOI: 10.1038/Cdd.2010.133  0.626
2011 Yu B, Dalton WB, Yang VW. Abstract 3890: Regulation of mediator of DNA damage checkpoint 1 (MDC1) during mitosis Cancer Research. 71: 3890-3890. DOI: 10.1158/1538-7445.Am2011-3890  0.369
2011 Garg P, Jeppsson S, Yang VW, Gewirtz AT, Merlin D, Sitaraman SV. MMP-9 mediates colitis associated cancer in mice through Notch-1 via p53 activation Inflammatory Bowel Diseases. 17: S9. DOI: 10.1097/00054725-201112002-00023  0.309
2011 Bialkowska A, Tian C, Yang VW. Identification of Small-Molecule Compounds That Inhibit the PRO-Proliferative Transcription Factor KrüPpel-Like Factor 5 (KLF5) in Colorectal Cancer Cells by Cell-Based High-Throughput Screen (HTS) Gastroenterology. 140: S-683. DOI: 10.1016/S0016-5085(11)62834-5  0.364
2011 McConnell BB, Kim SS, Ghaleb A, Takeda N, Manabe I, Nusrat A, Nagai R, Yang VW. KrüPpel-Like Factor 5 is a Key Factor for Maintenance of Crypt Architecture and Barrier Function in the Mouse Intestine Gastroenterology. 140: S-132. DOI: 10.1016/S0016-5085(11)60539-8  0.351
2011 Du JX, Yang VW. The E3 Ubiquitin Ligase, SMAD Ubiquitination Regulatory Factor 2 (SMURF2), Negatively Regulates the PRO-Proliferative KrüPpel-Like Factor 5 (KLF5) Gastroenterology. 140: S-105. DOI: 10.1016/S0016-5085(11)60426-5  0.327
2011 Ghaleb A, McConnell BB, Yang VW. Intestine-Specific Deletion of the KrüPpel-Like Factor 4 (KLF4) Gene Protects Mice From Dextran Sulfate Sodium (DSS)-Induced Colitis Gastroenterology. 140: S-84-S-85. DOI: 10.1016/S0016-5085(11)60345-4  0.368
2010 McConnell BB, Yang VW. Mammalian Krüppel-like factors in health and diseases. Physiological Reviews. 90: 1337-81. PMID 20959618 DOI: 10.1152/Physrev.00058.2009  0.37
2010 Patel NV, Ghaleb AM, Nandan MO, Yang VW. Expression of the tumor suppressor Krüppel-like factor 4 as a prognostic predictor for colon cancer. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 19: 2631-8. PMID 20699379 DOI: 10.1158/1055-9965.Epi-10-0677  0.424
2010 Du JX, McConnell BB, Yang VW. A small ubiquitin-related modifier-interacting motif functions as the transcriptional activation domain of Krüppel-like factor 4. The Journal of Biological Chemistry. 285: 28298-308. PMID 20584900 DOI: 10.1074/Jbc.M110.101717  0.365
2010 Yang X, Shi C, Tong R, Qian W, Zhau HE, Wang R, Zhu G, Cheng J, Yang VW, Cheng T, Henary M, Strekowski L, Chung LW. Near IR heptamethine cyanine dye-mediated cancer imaging. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 2833-44. PMID 20410058 DOI: 10.1158/1078-0432.Ccr-10-0059  0.337
2010 Nandan MO, Yang VW. Genetic and Chemical Models of Colorectal Cancer in Mice. Current Colorectal Cancer Reports. 6: 51-59. PMID 20376303 DOI: 10.1007/S11888-010-0046-1  0.335
2010 Nandan MO, Ghaleb AM, McConnell BB, Patel NV, Robine S, Yang VW. Krüppel-like factor 5 is a crucial mediator of intestinal tumorigenesis in mice harboring combined ApcMin and KRASV12 mutations. Molecular Cancer. 9: 63. PMID 20298593 DOI: 10.1186/1476-4598-9-63  0.402
2010 Dalton WB, Yu B, Yang VW. p53 suppresses structural chromosome instability after mitotic arrest in human cells. Oncogene. 29: 1929-40. PMID 20062083 DOI: 10.1038/Onc.2009.477  0.63
2010 Li S, Ghaleb AM, He J, Bughani U, Bialkowska AB, Yang VW, Joshi HC. Abstract 939: Chemoprevention of familial adenomatous polyposis by EM011 in theApcMin/+mouse model Cancer Research. 70: 939-939. DOI: 10.1158/1538-7445.Am10-939  0.379
2010 Garg P, Bialkowska A, Jeppsson S, Yang VW, Gewirtz AT, Merlin D, Sitaraman SV. M1935 MMP-9 Functions as a Tumor Suppressor in Colitis-Associated Cancer Through Its Effects on Cell Cycle Gastroenterology. 138: S-442-S-443. DOI: 10.1016/S0016-5085(10)62046-X  0.301
2010 McConnell BB, Kim SS, Nagai R, Yang VW. 866 Aberrant Intestinal Crypt Morphology and Cell Positioning in Mice With Intestine-Specific Deletion of the KrüPpel-Like Factor 5 Gene Gastroenterology. 138: S-120. DOI: 10.1016/S0016-5085(10)60549-5  0.393
2010 Ghaleb A, McConnell BB, Katz JP, Kaestner KH, Yang VW. 558 Intestine-Specific Deletion of the Mouse KrüPpel-Like Factor 4 Gene Results in Altered Homeostasis of Intestinal Epithelial Cells Gastroenterology. 138: S-78. DOI: 10.1016/S0016-5085(10)60353-8  0.409
2010 Nandan MO, Ghaleb A, McConnell BB, Yang VW. 176 KrüPpel-Like Factor 5 is a Crucial Mediator of Intestinal Tumorigenesis in Mice Harboring Combined APC and KRAS Mutations Gastroenterology. 138: S-32. DOI: 10.1016/S0016-5085(10)60147-3  0.333
2009 Dalton WB, Yang VW. Role of prolonged mitotic checkpoint activation in the formation and treatment of cancer. Future Oncology (London, England). 5: 1363-70. PMID 19903065 DOI: 10.2217/Fon.09.118  0.638
2009 McConnell BB, Yang VW. The Role of Inflammation in the Pathogenesis of Colorectal Cancer. Current Colorectal Cancer Reports. 5: 69-74. PMID 19756239 DOI: 10.1007/S11888-009-0011-Z  0.312
2009 Nandan MO, Yang VW. The role of Krüppel-like factors in the reprogramming of somatic cells to induced pluripotent stem cells. Histology and Histopathology. 24: 1343-55. PMID 19688699 DOI: 10.14670/Hh-24.1343  0.38
2009 Lin S, Wang D, Iyer S, Ghaleb AM, Shim H, Yang VW, Chun J, Yun CC. The absence of LPA2 attenuates tumor formation in an experimental model of colitis-associated cancer. Gastroenterology. 136: 1711-20. PMID 19328876 DOI: 10.1053/J.Gastro.2009.01.002  0.373
2009 Hagos EG, Ghaleb AM, Dalton WB, Bialkowska AB, Yang VW. Mouse embryonic fibroblasts null for the Krüppel-like factor 4 gene are genetically unstable. Oncogene. 28: 1197-205. PMID 19137014 DOI: 10.1038/Onc.2008.465  0.651
2009 Lin S, Ghaleb A, Shim H, Yang VW, Chun J, Yun CC. 720 The Absence of LPA2 Attenuates Tumor Formation in Both An Animal Model of Colitis-Associated Cancer and APCMIN/+ Mice Gastroenterology. 136: A-115. DOI: 10.1016/S0016-5085(09)60515-1  0.305
2009 Nandan MO, Ghaleb A, McConnell BB, Yang VW. 572 Haploinsufficiency of Krüppel-Like Factor 5 (KLF5) Reduces Intestinal Adenoma Formation in KRasV12G/Apcmin/+ Mice Gastroenterology. 136: A-90-A-91. DOI: 10.1016/S0016-5085(09)60407-8  0.352
2008 Ghaleb AM, Aggarwal G, Bialkowska AB, Nandan MO, Yang VW. Notch inhibits expression of the Krüppel-like factor 4 tumor suppressor in the intestinal epithelium. Molecular Cancer Research : McR. 6: 1920-7. PMID 19074836 DOI: 10.1158/1541-7786.Mcr-08-0224  0.428
2008 Guo L, Zhong D, Lau S, Liu X, Dong XY, Sun X, Yang VW, Vertino PM, Moreno CS, Varma V, Dong JT, Zhou W. Sox7 Is an independent checkpoint for beta-catenin function in prostate and colon epithelial cells. Molecular Cancer Research : McR. 6: 1421-30. PMID 18819930 DOI: 10.1158/1541-7786.Mcr-07-2175  0.303
2008 Du JX, Bialkowska AB, McConnell BB, Yang VW. SUMOylation regulates nuclear localization of Krüppel-like factor 5. The Journal of Biological Chemistry. 283: 31991-2002. PMID 18782761 DOI: 10.1074/Jbc.M803612200  0.349
2008 Ghaleb AM, Yang VW. The Pathobiology of Krüppel-like Factors in Colorectal Cancer. Current Colorectal Cancer Reports. 4: 59-64. PMID 18504508 DOI: 10.1007/S11888-008-0011-4  0.403
2008 Shao J, Yang VW, Sheng H. Prostaglandin E2 and Krüppel-like transcription factors synergistically induce the expression of decay-accelerating factor in intestinal epithelial cells. Immunology. 125: 397-407. PMID 18435741 DOI: 10.1111/J.1365-2567.2008.02847.X  0.427
2008 McConnell BB, Klapproth JM, Sasaki M, Nandan MO, Yang VW. Krüppel-like factor 5 mediates transmissible murine colonic hyperplasia caused by Citrobacter rodentium infection. Gastroenterology. 134: 1007-16. PMID 18395082 DOI: 10.1053/J.Gastro.2008.01.013  0.415
2008 Yusuf I, Kharas MG, Chen J, Peralta RQ, Maruniak A, Sareen P, Yang VW, Kaestner KH, Fruman DA. KLF4 is a FOXO target gene that suppresses B cell proliferation. International Immunology. 20: 671-81. PMID 18375530 DOI: 10.1093/Intimm/Dxn024  0.378
2008 Nandan MO, McConnell BB, Ghaleb AM, Bialkowska AB, Sheng H, Shao J, Babbin BA, Robine S, Yang VW. Krüppel-like factor 5 mediates cellular transformation during oncogenic KRAS-induced intestinal tumorigenesis. Gastroenterology. 134: 120-30. PMID 18054006 DOI: 10.1053/J.Gastro.2007.10.023  0.434
2008 Ngwenya SK, Bialkowska A, Yang VW. S1992 Induction of KrüPpel-Like Factor 5 By Lipopolysaccharide in Intestinal Epithelial Cells Is Mediated By Mitogen-Activated Protein Kinase and Phosphatidylinositol 3-Kinase Pathways Gastroenterology. 134: A-293. DOI: 10.1016/S0016-5085(08)61362-1  0.347
2008 Hagos EG, Ghaleb A, Dalton WB, Katz JP, Kaestner KH, Yang VW. 616 Mouse Embryonic Fibroblasts Null for the KrüPpel-Like Factor 4 Alleles Are Genetically Unstable Gastroenterology. 134: A-86. DOI: 10.1016/S0016-5085(08)60406-0  0.611
2008 McConnell BB, Bialkowska A, Nandan MO, Ghaleb A, Yang VW. 536 Haploinsufficiency of KrüPpel-Like Factor 5 Inhibits Adenoma Formation in APCMin/+ Mice By Modulating β-Catenin Activity Gastroenterology. 134: A-76-A-77. DOI: 10.1016/S0016-5085(08)60360-1  0.305
2008 Ghaleb A, Aggarwal G, Bialkowska A, Nandan MO, Yang VW. 192 Notch Signaling Regulates Expression of the KrüPpel-Like Factor 4 Gene in the Intestinal Epithelium Gastroenterology. 134: A-33. DOI: 10.1016/S0016-5085(08)60161-4  0.35
2007 Dalton WB, Yang VW. Mitotic Origins of Chromosomal Instability in Colorectal Cancer. Current Colorectal Cancer Reports. 3: 59-64. PMID 18843382 DOI: 10.1007/S11888-007-0001-Y  0.624
2007 Dalton WB, Nandan MO, Moore RT, Yang VW. Human cancer cells commonly acquire DNA damage during mitotic arrest. Cancer Research. 67: 11487-92. PMID 18089775 DOI: 10.1158/0008-5472.Can-07-5162  0.642
2007 Ghaleb AM, McConnell BB, Nandan MO, Katz JP, Kaestner KH, Yang VW. Haploinsufficiency of Krüppel-like factor 4 promotes adenomatous polyposis coli dependent intestinal tumorigenesis. Cancer Research. 67: 7147-54. PMID 17671182 DOI: 10.1158/0008-5472.Can-07-1302  0.376
2007 Rusovici R, Ghaleb A, Shim H, Yang VW, Yun CC. Lysophosphatidic acid prevents apoptosis of Caco-2 colon cancer cells via activation of mitogen-activated protein kinase and phosphorylation of Bad. Biochimica Et Biophysica Acta. 1770: 1194-203. PMID 17544220 DOI: 10.1016/J.Bbagen.2007.04.008  0.374
2007 McConnell BB, Ghaleb AM, Nandan MO, Yang VW. The diverse functions of Krüppel-like factors 4 and 5 in epithelial biology and pathobiology. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 29: 549-57. PMID 17508399 DOI: 10.1002/Bies.20581  0.431
2007 Aneja R, Ghaleb AM, Zhou J, Yang VW, Joshi HC. p53 and p21 determine the sensitivity of noscapine-induced apoptosis in colon cancer cells. Cancer Research. 67: 3862-70. PMID 17440101 DOI: 10.1158/0008-5472.Can-06-4282  0.308
2007 Zhang H, Bialkowska A, Rusovici R, Chanchevalap S, Shim H, Katz JP, Yang VW, Yun CC. Lysophosphatidic acid facilitates proliferation of colon cancer cells via induction of Krüppel-like factor 5. The Journal of Biological Chemistry. 282: 15541-9. PMID 17430902 DOI: 10.1074/jbc.M700702200  0.319
2007 Kharas MG, Yusuf I, Scarfone VM, Yang VW, Segre JA, Huettner CS, Fruman DA. KLF4 suppresses transformation of pre-B cells by ABL oncogenes. Blood. 109: 747-55. PMID 16954505 DOI: 10.1182/Blood-2006-03-011106  0.378
2006 Hisamuddin IM, Yang VW. Molecular Genetics of Colorectal Cancer: An Overview. Current Colorectal Cancer Reports. 2: 53-59. PMID 19079560 DOI: 10.1007/S11888-006-0002-2  0.319
2006 Whitney EM, Ghaleb AM, Chen X, Yang VW. Transcriptional profiling of the cell cycle checkpoint gene krüppel-like factor 4 reveals a global inhibitory function in macromolecular biosynthesis. Gene Expression. 13: 85-96. PMID 17017123 DOI: 10.3727/000000006783991908  0.394
2006 Ghaleb AM, Katz JP, Kaestner KH, Du JX, Yang VW. Krüppel-like factor 4 exhibits antiapoptotic activity following gamma-radiation-induced DNA damage. Oncogene. 26: 2365-73. PMID 17016435 DOI: 10.1038/Sj.Onc.1210022  0.409
2006 Blanchon L, Nores R, Gallot D, Marceau G, Borel V, Yang VW, Bocco JL, Lémery D, Panzetta-Dutari G, Sapin V. Activation of the human pregnancy-specific glycoprotein PSG-5 promoter by KLF4 and Sp1. Biochemical and Biophysical Research Communications. 343: 745-53. PMID 16563348 DOI: 10.1016/J.Bbrc.2006.03.032  0.335
2006 Zhang W, Chen X, Kato Y, Evans PM, Yuan S, Yang J, Rychahou PG, Yang VW, He X, Evers BM, Liu C. Novel cross talk of Kruppel-like factor 4 and beta-catenin regulates normal intestinal homeostasis and tumor repression. Molecular and Cellular Biology. 26: 2055-64. PMID 16507986 DOI: 10.1128/Mcb.26.6.2055-2064.2006  0.375
2006 Chanchevalap S, Nandan MO, McConnell BB, Charrier L, Merlin D, Katz JP, Yang VW. Kruppel-like factor 5 is an important mediator for lipopolysaccharide-induced proinflammatory response in intestinal epithelial cells. Nucleic Acids Research. 34: 1216-23. PMID 16500892 DOI: 10.1093/Nar/Gkl014  0.31
2005 Nandan MO, Chanchevalap S, Dalton WB, Yang VW. Krüppel-like factor 5 promotes mitosis by activating the cyclin B1/Cdc2 complex during oncogenic Ras-mediated transformation. Febs Letters. 579: 4757-62. PMID 16102754 DOI: 10.1016/J.Febslet.2005.07.053  0.622
2005 Yoon HS, Ghaleb AM, Nandan MO, Hisamuddin IM, Dalton WB, Yang VW. Krüppel-like factor 4 prevents centrosome amplification following gamma-irradiation-induced DNA damage. Oncogene. 24: 4017-25. PMID 15806166 DOI: 10.1038/Sj.Onc.1208576  0.654
2005 Ghaleb AM, Nandan MO, Chanchevalap S, Dalton WB, Hisamuddin IM, Yang VW. Krüppel-like factors 4 and 5: the yin and yang regulators of cellular proliferation. Cell Research. 15: 92-6. PMID 15740636 DOI: 10.1038/Sj.Cr.7290271  0.661
2004 Chanchevalap S, Nandan MO, Merlin D, Yang VW. All-trans retinoic acid inhibits proliferation of intestinal epithelial cells by inhibiting expression of the gene encoding Kruppel-like factor 5. Febs Letters. 578: 99-105. PMID 15581624 DOI: 10.1016/J.Febslet.2004.10.079  0.421
2004 Nandan MO, Yoon HS, Zhao W, Ouko LA, Chanchevalap S, Yang VW. Krüppel-like factor 5 mediates the transforming activity of oncogenic H-Ras. Oncogene. 23: 3404-13. PMID 15077182 DOI: 10.1038/Sj.Onc.1207397  0.318
2004 Zhao W, Hisamuddin IM, Nandan MO, Babbin BA, Lamb NE, Yang VW. Identification of Krüppel-like factor 4 as a potential tumor suppressor gene in colorectal cancer. Oncogene. 23: 395-402. PMID 14724568 DOI: 10.1038/Sj.Onc.1207067  0.392
2004 Piccinni SA, Bolcato-Bellemin AL, Klein A, Yang VW, Kedinger M, Simon-Assmann P, Lefebvre O. Kruppel-like factors regulate the Lama1 gene encoding the laminin alpha1 chain. The Journal of Biological Chemistry. 279: 9103-14. PMID 14634001 DOI: 10.1074/Jbc.M305804200  0.377
2004 Yoon HS, Yang VW. Requirement of Krüppel-like factor 4 in preventing entry into mitosis following DNA damage. The Journal of Biological Chemistry. 279: 5035-41. PMID 14627709 DOI: 10.1074/Jbc.M307631200  0.368
2004 Hinnebusch BF, Siddique A, Henderson JW, Malo MS, Zhang W, Athaide CP, Abedrapo MA, Chen X, Yang VW, Hodin RA. Enterocyte differentiation marker intestinal alkaline phosphatase is a target gene of the gut-enriched Kruppel-like factor. American Journal of Physiology. Gastrointestinal and Liver Physiology. 286: G23-30. PMID 12919939 DOI: 10.1152/Ajpgi.00203.2003  0.379
2003 Siddique A, Malo MS, Ocuin LM, Hinnebusch BF, Abedrapo MA, Henderson JW, Zhang W, Mozumder M, Yang VW, Hodin RA. Convergence of the thyroid hormone and gut-enriched Krüppel-like factor pathways in the context of enterocyte differentiation. Journal of Gastrointestinal Surgery : Official Journal of the Society For Surgery of the Alimentary Tract. 7: 1053-61; discussion . PMID 14675715 DOI: 10.1016/J.Gassur.2003.09.006  0.337
2003 Dang DT, Chen X, Feng J, Torbenson M, Dang LH, Yang VW. Overexpression of Krüppel-like factor 4 in the human colon cancer cell line RKO leads to reduced tumorigenecity. Oncogene. 22: 3424-30. PMID 12776194 DOI: 10.1038/Sj.Onc.1206413  0.456
2003 Chen X, Whitney EM, Gao SY, Yang VW. Transcriptional profiling of Krüppel-like factor 4 reveals a function in cell cycle regulation and epithelial differentiation. Journal of Molecular Biology. 326: 665-77. PMID 12581631 DOI: 10.1016/S0022-2836(02)01449-3  0.376
2003 Yoon HS, Chen X, Yang VW. Kruppel-like factor 4 mediates p53-dependent G1/S cell cycle arrest in response to DNA damage. The Journal of Biological Chemistry. 278: 2101-5. PMID 12427745 DOI: 10.1074/Jbc.M211027200  0.363
2003 Ouko L, Gu LH, Ziegler TR, Yang VW. Wnt 11 signaling induces proliferation and transformation of intestinal epithelial cells Iec6 and is mediated by a protein kinase C-dependent mechanism Gastroenterology. 124: A599. DOI: 10.1016/S0016-5085(03)83037-8  0.324
2003 Zhao W, Hisamuddin IM, Yang VW. Comparison of the expression levels of the genes encoding Krüppel-like factor 4 (KLF4), Krüppel-like factor 5 (KLF5) and p21WAF1/CIP1 in matched normal and cancerous tissues of the colon Gastroenterology. 124: A364. DOI: 10.1016/S0016-5085(03)81842-5  0.368
2003 Nandan M, Yang VW. KrÜppel-like factor 5 (KLF5) mediates Ha-Ras-induced cell transformation Gastroenterology. 124: A57. DOI: 10.1016/S0016-5085(03)80279-2  0.311
2002 Dang DT, Zhao W, Mahatan CS, Geiman DE, Yang VW. Opposing effects of Krüppel-like factor 4 (gut-enriched Krüppel-like factor) and Krüppel-like factor 5 (intestinal-enriched Krüppel-like factor) on the promoter of the Krüppel-like factor 4 gene. Nucleic Acids Research. 30: 2736-41. PMID 12087155 DOI: 10.1093/Nar/Gkf400  0.435
2002 Katz JP, Perreault N, Goldstein BG, Lee CS, Labosky PA, Yang VW, Kaestner KH. The zinc-finger transcription factor Klf4 is required for terminal differentiation of goblet cells in the colon. Development (Cambridge, England). 129: 2619-28. PMID 12015290 DOI: 10.1242/dev.129.11.2619  0.317
2002 Gala M, Sun R, Yang VW. Inhibition of cell transformation by sulindac sulfide is confined to specific oncogenic pathways. Cancer Letters. 175: 89-94. PMID 11734340 DOI: 10.1016/S0304-3835(01)00716-9  0.347
2001 Dang DT, Mahatan CS, Dang LH, Agboola IA, Yang VW. Expression of the gut-enriched Krüppel-like factor (Krüppel-like factor 4) gene in the human colon cancer cell line RKO is dependent on CDX2. Oncogene. 20: 4884-90. PMID 11521200 DOI: 10.1038/Sj.Onc.1204645  0.433
2001 Chen X, Johns DC, Geiman DE, Marban E, Dang DT, Hamlin G, Sun R, Yang VW. Krüppel-like factor 4 (gut-enriched Krüppel-like factor) inhibits cell proliferation by blocking G1/S progression of the cell cycle. The Journal of Biological Chemistry. 276: 30423-8. PMID 11390382 DOI: 10.1074/Jbc.M101194200  0.417
2001 Sun R, Chen X, Yang VW. Intestinal-enriched Krüppel-like factor (Krüppel-like factor 5) is a positive regulator of cellular proliferation. The Journal of Biological Chemistry. 276: 6897-900. PMID 11152667 DOI: 10.1074/Jbc.C000870200  0.436
2001 Mahatan CS, Geiman DE, Yang VW. Opposing effects of gut-enriched kruppel-like factor (GKLF) and intestinal-enriched kruppel-like factor (IKLF) on the promoter on the GKLF gene Gastroenterology. 120: A703. DOI: 10.1016/S0016-5085(08)83502-0  0.37
2001 Sun R, Chen X, Yang VW. Intestinal-enriched kruppel-like factor (IKLF) is a delayed early response gene that positively regulates cellular proliferation Gastroenterology. 120: A501. DOI: 10.1016/S0016-5085(08)82488-2  0.361
2001 Chen X, Johns DC, Geiman DE, Marban E, Yang VW. Gut-enriched kruppel-like factor (GKLF) inhibits cellular proliferation by blocking the G1/S boundary of the cell cycle Gastroenterology. 120: A103. DOI: 10.1016/S0016-5085(08)80506-9  0.334
2000 Dang DT, Pevsner J, Yang VW. The biology of the mammalian Krüppel-like family of transcription factors. The International Journal of Biochemistry & Cell Biology. 32: 1103-21. PMID 11137451 DOI: 10.1016/S1357-2725(00)00059-5  0.359
2000 Yang VW. The molecular genetics of colorectal cancer. Current Gastroenterology Reports. 1: 449-54. PMID 10980985 DOI: 10.1007/S11894-999-0028-0  0.321
2000 Dang DT, Bachman KE, Mahatan CS, Dang LH, Giardiello FM, Yang VW. Decreased expression of the gut-enriched Krüppel-like factor gene in intestinal adenomas of multiple intestinal neoplasia mice and in colonic adenomas of familial adenomatous polyposis patients. Febs Letters. 476: 203-7. PMID 10913614 DOI: 10.1016/S0014-5793(00)01727-0  0.398
2000 Zhang W, Geiman DE, Shields JM, Dang DT, Mahatan CS, Kaestner KH, Biggs JR, Kraft AS, Yang VW. The gut-enriched Kruppel-like factor (Kruppel-like factor 4) mediates the transactivating effect of p53 on the p21(WAF1)/(Cip)1 promoter Journal of Biological Chemistry. 275: 18391-18398. PMID 10749849 DOI: 10.1074/Jbc.C000062200  0.302
2000 Dang DT, Bachman KE, Romans KE, Hylind LM, Giardiello FM, Yang VW. Decreased expression of the gut enriched kruppel-like factor (GKLF) gene in intestinal adenomas of multiple intestinal neoplasia (Min) mice and in colonic adenomas of familial adenomatosis polyposis (FAP) patients Gastroenterology. 118: A671. DOI: 10.1016/S0016-5085(00)84822-2  0.363
2000 Dang DT, Mahatan CS, Corn PG, Dang LH, Yang VW. Expression of the gut enriched kruppel-like factor (GKLF) gene in the human colon cancer cell line RKO is dependent on CDX2 Gastroenterology. 118: A590. DOI: 10.1016/S0016-5085(00)84499-6  0.389
2000 Katz JP, Yang VW, Kaestner KH. The zinc-finger transcription factor Klf4 in the regulation of gastrointestinal epithelial proliferation and differentiation in vivo Gastroenterology. 118: A289. DOI: 10.1016/S0016-5085(00)83243-6  0.381
1998 Yang VW. Eukaryotic transcription factors: identification, characterization and functions. The Journal of Nutrition. 128: 2045-51. PMID 9808664 DOI: 10.1093/Jn/128.11.2045  0.331
1998 Zhang W, Shields JM, Sogawa K, Fujii-Kuriyama Y, Yang VW. The gut-enriched Kruppel-like factor suppresses the activity of the CYP1a1 promoter in an Sp1-dependent fashion Journal of Biological Chemistry. 273: 17917-17925. PMID 9651398 DOI: 10.1074/Jbc.273.28.17917  0.35
1998 Shields JM, Yang VW. Identification of the DNA sequence that interacts with the gut-enriched Kruppel-like factor Nucleic Acids Research. 26: 796-802. PMID 9443972 DOI: 10.1093/Nar/26.3.796  0.319
1997 Shields JM, Yang VW. Two potent nuclear localization signals in the gut-enriched Kruppel- like factor define a subfamily of closely related Kruppel proteins Journal of Biological Chemistry. 272: 18504-18507. PMID 9218496 DOI: 10.1074/Jbc.272.29.18504  0.316
1996 Majewski JL, Yang VW. The class I alcohol dehydrogenase gene is glucocorticoid-responsive in the rat hepatoma microcell hybrid cell line, 11-3. Alcoholism, Clinical and Experimental Research. 19: 1430-4. PMID 8749806 DOI: 10.1111/J.1530-0277.1995.Tb01003.X  0.316
1996 Shields JM, Christy RJ, Yang VW. Identification and characterization of a gene encoding a gut-enriched Kruppel-like factor expressed during growth arrest Journal of Biological Chemistry. 271: 20009-20017. PMID 8702718 DOI: 10.1074/Jbc.271.33.20009  0.398
1995 Cortese JF, Spannhake EW, Eisinger W, Potter JJ, Yang VW. The 5-lipoxygenase pathway in cultured human intestinal epithelial cells Prostaglandins. 49: 155-166. PMID 7652184 DOI: 10.1016/0090-6980(95)00003-S  0.32
1995 Oliva MM, Cortese JF, Yang VW. Promoter regulation of a differentially expressed gene in the human colonic epithelial cell lines HT29-18 and HT29-18-C1 Gene. 159: 151-157. PMID 7622043 DOI: 10.1016/0378-1119(95)00130-X  0.308
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