| Year |
Citation |
Score |
| 2023 |
Alexander SPH, Christopoulos A, Davenport AP, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA, Abbracchio MP, Abraham G, Agoulnik A, Alexander W, ... ... Escher E, et al. The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors. British Journal of Pharmacology. S23-S144. PMID 38123151 DOI: 10.1111/bph.16177 |
0.313 |
|
| 2021 |
Alexander SP, Christopoulos A, Davenport AP, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Southan C, Davies JA, Abbracchio MP, Alexander W, ... ... Escher E, et al. THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors. British Journal of Pharmacology. 178: S27-S156. PMID 34529832 DOI: 10.1111/bph.15538 |
0.306 |
|
| 2019 |
Alexander W, Bernstein KE, Catt KJ, De Gasparo M, Dhanachandra Singh K, Eguchi S, Escher E, Goodfriend TL, Horiuchi M, Hunyady L, Husain A, Inagami T, Karnik S, Kemp J, Thomas WG, et al. Angiotensin receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database Iuphar/Bps Guide to Pharmacology Cite. 2019. DOI: 10.2218/gtopdb/f6/2019.4 |
0.482 |
|
| 2018 |
St-Pierre D, Cabana J, Holleran BJ, Besserer-Offroy É, Escher E, Guillemette G, Lavigne P, Leduc R. Angiotensin II cyclic analogs as tools to investigate ATR biased signaling mechanisms. Biochemical Pharmacology. PMID 29684376 DOI: 10.1016/J.Bcp.2018.04.021 |
0.534 |
|
| 2017 |
Mona CE, Besserer-Offroy É, Cabana J, Lefrançois M, Boulais PE, Lefebvre M, Leduc R, Lavigne P, Heveker N, Marsault É, Escher E. Agonist-Antagonist Transition in CXCR4 Ligands Journal of Pharmacological and Toxicological Methods. 88: 170-171. DOI: 10.1016/J.Vascn.2017.09.012 |
0.4 |
|
| 2016 |
Mona CE, Besserer-Offroy É, Cabana J, Leduc R, Lavigne P, Heveker N, Marsault É, Escher E. Design, synthesis, and biological evaluation of CXCR4 ligands. Organic & Biomolecular Chemistry. PMID 27752700 DOI: 10.1039/C6Ob01484D |
0.515 |
|
| 2016 |
Mona CE, Besserer-Offroy É, Cabana J, Lefrançois M, Boulais PE, Lefebvre MR, Leduc R, Lavigne P, Heveker N, Marsault E, Escher E. Structure Activity Relationship and Signaling of New Chimeric CXCR4 Agonists. Journal of Medicinal Chemistry. PMID 27434274 DOI: 10.1021/Acs.Jmedchem.6B00566 |
0.552 |
|
| 2015 |
Cabana J, Holleran B, Leduc R, Escher E, Guillemette G, Lavigne P. Identification of Distinct Conformations of the Angiotensin-II Type 1 Receptor Associated with the Gq/11 Protein Pathway and the β-Arrestin Pathway Using Molecular Dynamics Simulations. The Journal of Biological Chemistry. 290: 15835-54. PMID 25934394 DOI: 10.1074/Jbc.M114.627356 |
0.56 |
|
| 2015 |
Domazet I, Holleran BJ, Richard A, Vandenberghe C, Lavigne P, Escher E, Leduc R, Guillemette G. Characterization of Angiotensin II Molecular Determinants Involved in AT1 Receptor Functional Selectivity. Molecular Pharmacology. 87: 982-95. PMID 25808928 DOI: 10.1124/Mol.114.097337 |
0.53 |
|
| 2015 |
Cabana J, Holleran B, Leduc R, Escher E, Guillemette G, Lavigne P. Identification of distinct conformations of the angiotensin-II type 1 receptor associated with the Gq/11 protein pathway and the β-arrestin pathway using molecular dynamics simulations Journal of Biological Chemistry. 290: 15835-15854. DOI: 10.1074/jbc.M114.627356 |
0.313 |
|
| 2014 |
Sainsily X, Cabana J, Holleran BJ, Escher E, Lavigne P, Leduc R. Identification of transmembrane domain 1 & 2 residues that contribute to the formation of the ligand-binding pocket of the urotensin-II receptor Biochemical Pharmacology. 92: 280-288. PMID 25175740 DOI: 10.1016/j.bcp.2014.08.023 |
0.469 |
|
| 2013 |
Sainsily X, Cabana J, Boulais PE, Holleran BJ, Escher E, Lavigne P, Leduc R. Identification of transmembrane domain 3, 4 & 5 residues that contribute to the formation of the ligand-binding pocket of the urotensin-II receptor Biochemical Pharmacology. 86: 1584-1593. PMID 24084430 DOI: 10.1016/J.Bcp.2013.09.015 |
0.577 |
|
| 2013 |
Fillion D, Cabana J, Guillemette G, Leduc R, Lavigne P, Escher E. Structure of the human angiotensin II type 1 (AT1) receptor bound to angiotensin II from multiple chemoselective photoprobe contacts reveals a unique peptide binding mode Journal of Biological Chemistry. 288: 8187-8197. PMID 23386604 DOI: 10.1074/Jbc.M112.442053 |
0.637 |
|
| 2013 |
Cabana J, Holleran B, Beaulieu ME, Leduc R, Escher E, Guillemette G, Lavigne P. Critical hydrogen bond formation for activation of the angiotensin ii type 1 receptor Journal of Biological Chemistry. 288: 2593-2604. PMID 23223579 DOI: 10.1074/Jbc.M112.395939 |
0.567 |
|
| 2013 |
Boulais PE, Escher E, Leduc R. Analysis by substituted cysteine scanning mutagenesis of the fourth transmembrane domain of the CXCR4 receptor in its inactive and active state. Biochemical Pharmacology. 85: 541-50. PMID 23219524 DOI: 10.1016/J.Bcp.2012.11.022 |
0.461 |
|
| 2012 |
Zimmerman B, Beautrait A, Aguila B, Charles R, Escher E, Claing A, Bouvier M, Laporte SA. Differential β-arrestin-dependent conformational signaling and cellular responses revealed by angiotensin analogs. Science Signaling. 5: ra33. PMID 22534132 DOI: 10.1126/Scisignal.2002522 |
0.456 |
|
| 2012 |
Wangler NJ, Santos KL, Schadock I, Hagen FK, Escher E, Bader M, Speth RC, Karamyan VT. Identification of membrane-bound variant of metalloendopeptidase neurolysin (EC 3.4.24.16) as the non-angiotensin type 1 (non-AT1), non-AT2 angiotensin binding site. The Journal of Biological Chemistry. 287: 114-22. PMID 22039052 DOI: 10.1074/Jbc.M111.273052 |
0.427 |
|
| 2011 |
Lefrançois M, Lefebvre MR, Saint-Onge G, Boulais PE, Lamothe S, Leduc R, Lavigne P, Heveker N, Escher E. Agonists for the Chemokine Receptor CXCR4. Acs Medicinal Chemistry Letters. 2: 597-602. PMID 21841963 DOI: 10.1021/Ml200084N |
0.54 |
|
| 2010 |
Karamyan VT, Arsenault J, Escher E, Speth RC. Preliminary biochemical characterization of the novel, non-AT1, non-AT2 angiotensin binding site from the rat brain. Endocrine. 37: 442-8. PMID 20960166 DOI: 10.1007/S12020-010-9328-2 |
0.522 |
|
| 2010 |
Arsenault J, Cabana J, Fillion D, Leduc R, Guillemette G, Lavigne P, Escher E. Temperature dependent photolabeling of the human angiotensin II type 1 receptor reveals insights into its conformational landscape and its activation mechanism Biochemical Pharmacology. 80: 990-999. PMID 20599798 DOI: 10.1016/J.Bcp.2010.06.004 |
0.563 |
|
| 2010 |
Mulumba M, Jossart C, Granata R, Gallo D, Escher E, Ghigo E, Servant MJ, Marleau S, Ong H. GPR103b functions in the peripheral regulation of adipogenesis. Molecular Endocrinology (Baltimore, Md.). 24: 1615-25. PMID 20534693 DOI: 10.1210/Me.2010-0010 |
0.303 |
|
| 2010 |
Arsenault J, Lehoux J, Lanthier L, Cabana J, Guillemette G, Lavigne P, Leduc R, Escher E. A single-nucleotide polymorphism of alanine to threonine at position 163 of the human angiotensin II type 1 receptor impairs Losartan affinity Pharmacogenetics and Genomics. 20: 377-388. PMID 20436376 DOI: 10.1097/Fpc.0B013E32833A6D4A |
0.476 |
|
| 2010 |
Fillion D, Lemieux G, Basambombo LL, Lavigne P, Guillemette G, Leduc R, Escher E. The amino-terminus of angiotensin II contacts several ectodomains of the angiotensin II receptor AT1. Journal of Medicinal Chemistry. 53: 2063-75. PMID 20146480 DOI: 10.1021/Jm9015747 |
0.637 |
|
| 2010 |
Yan L, Holleran BJ, Lavigne P, Escher E, Guillemette G, Leduc R. Analysis of transmembrane domains 1 and 4 of the human angiotensin II AT1 receptor by cysteine-scanning mutagenesis. The Journal of Biological Chemistry. 285: 2284-93. PMID 19940150 DOI: 10.1074/Jbc.M109.077180 |
0.599 |
|
| 2009 |
Domazet I, Martin SS, Holleran BJ, Morin ME, Lacasse P, Lavigne P, Escher E, Leduc R, Guillemette G. The fifth transmembrane domain of angiotensin II Type 1 receptor participates in the formation of the ligand-binding pocket and undergoes a counterclockwise rotation upon receptor activation. The Journal of Biological Chemistry. 284: 31953-61. PMID 19773549 DOI: 10.1074/Jbc.M109.051839 |
0.604 |
|
| 2009 |
Clément M, Cabana J, Holleran BJ, Leduc R, Guillemette G, Lavigne P, Escher E. Activation induces structural changes in the liganded angiotensin II type 1 receptor Journal of Biological Chemistry. 284: 26603-26612. PMID 19635801 DOI: 10.1074/Jbc.M109.012922 |
0.596 |
|
| 2009 |
Boulais PE, Dulude D, Cabana J, Heveker N, Escher E, Lavigne P, Leduc R. Photolabeling identifies transmembrane domain 4 of CXCR4 as a T140 binding site Biochemical Pharmacology. 78: 1382-1390. PMID 19631193 DOI: 10.1016/J.Bcp.2009.07.007 |
0.407 |
|
| 2009 |
Holleran BJ, Domazet I, Beaulieu ME, Yan LP, Guillemette G, Lavigne P, Escher E, Leduc R. Identification of transmembrane domain 6 & 7 residues that contribute to the binding pocket of the urotensin II receptor. Biochemical Pharmacology. 77: 1374-82. PMID 19426676 DOI: 10.1016/J.Bcp.2009.01.013 |
0.606 |
|
| 2009 |
Clément M, Guillemette G, Leduc R, Escher E. Structural changes in the binding pocket of the liganded angiotensin II receptor AT1 during activation. Advances in Experimental Medicine and Biology. 611: 341-2. PMID 19400219 DOI: 10.1007/978-0-387-73657-0_152 |
0.556 |
|
| 2009 |
Arsenault J, Renaud MP, Clément M, Fillion D, Guillemette G, Leduc R, Lavigne P, Escher E. Temperature-induced ligand contact point variations of the hAT1 receptor and of the constitutively active mutant N111G-hAT1. Advances in Experimental Medicine and Biology. 611: 339-40. PMID 19400218 DOI: 10.1007/978-0-387-73657-0_151 |
0.458 |
|
| 2009 |
Fillion D, Guillemette G, Leduc R, Escher E. Photoprobe peptides to map the interactions of angiotensin II with its receptor AT1. Advances in Experimental Medicine and Biology. 611: 329-30. PMID 19400214 DOI: 10.1007/978-0-387-73657-0_147 |
0.517 |
|
| 2009 |
Domazet I, Holleran BJ, Martin SS, Lavigne P, Leduc R, Escher E, Guillemette G. The second transmembrane domain of the human type 1 angiotensin II receptor participates in the formation of the ligand binding pocket and undergoes integral pivoting movement during the process of receptor activation. The Journal of Biological Chemistry. 284: 11922-9. PMID 19276075 DOI: 10.1074/Jbc.M808113200 |
0.604 |
|
| 2008 |
Proulx CD, Holleran BJ, Boucard AA, Escher E, Guillemette G, Leduc R. Mutational analysis of the conserved Asp2.50 and ERY motif reveals signaling bias of the urotensin II receptor. Molecular Pharmacology. 74: 552-61. PMID 18509066 DOI: 10.1124/Mol.108.045054 |
0.47 |
|
| 2008 |
Proulx CD, Holleran BJ, Lavigne P, Escher E, Guillemette G, Leduc R. Biological properties and functional determinants of the urotensin II receptor. Peptides. 29: 691-9. PMID 18155322 DOI: 10.1016/J.Peptides.2007.10.027 |
0.544 |
|
| 2008 |
Leclerc PC, Proulx CD, Arguin G, Bélanger S, Gobeil F, Escher E, Leduc R, Guillemette G. Ascorbic acid decreases the binding affinity of the AT1 receptor for angiotensin II. American Journal of Hypertension. 21: 67-71. PMID 18091746 DOI: 10.1038/Ajh.2007.1 |
0.469 |
|
| 2007 |
Arsenault J, Renaud MP, Clément M, Fillion D, Guillemette G, Leduc R, Lavigne P, Escher E. Temperature-dependent variations of ligand-receptor contact points in hAT(1). Journal of Peptide Science : An Official Publication of the European Peptide Society. 13: 575-80. PMID 17600857 DOI: 10.1002/Psc.875 |
0.533 |
|
| 2007 |
Martin SS, Holleran BJ, Escher E, Guillemette G, Leduc R. Activation of the angiotensin II type 1 receptor leads to movement of the sixth transmembrane domain: analysis by the substituted cysteine accessibility method. Molecular Pharmacology. 72: 182-90. PMID 17446269 DOI: 10.1124/Mol.106.033670 |
0.563 |
|
| 2007 |
Holleran BJ, Beaulieu ME, Proulx CD, Lavigne P, Escher E, Leduc R. Photolabelling the urotensin II receptor reveals distinct agonist- and partial-agonist-binding sites. The Biochemical Journal. 402: 51-61. PMID 17064254 DOI: 10.1042/Bj20060943 |
0.607 |
|
| 2006 |
Clément M, Escher E. [The methionine proximity assay: an approach to glean receptor structures]. MéDecine Sciences : M/S. 22: 1017-8. PMID 17156715 DOI: 10.1051/medsci/200622121017 |
0.379 |
|
| 2006 |
Gagnon T, Fillion D, Lefebvre MR, Escher E. Synthesis of an agonistic, difluoro-azido photolabel of angiotensin II and labeling of the AT1 receptor: transmembrane domains 3, 6, and 7 form the ligand-binding pocket. Journal of Receptor and Signal Transduction Research. 26: 435-51. PMID 17118791 DOI: 10.1080/10799890600923161 |
0.625 |
|
| 2006 |
Clément M, Chamberland C, Pérodin J, Leduc R, Guillemette G, Escher E. The active and the inactive form of the hAT1 receptor have an identical ligand-binding environment: an MPA study on a constitutively active angiotensin II receptor mutant. Journal of Receptor and Signal Transduction Research. 26: 417-33. PMID 17118790 DOI: 10.1080/10799890600923195 |
0.614 |
|
| 2006 |
Fillion D, Deraët M, Holleran BJ, Escher E. Stereospecific synthesis of a carbene-generating angiotensin II analogue for comparative photoaffinity labeling: improved incorporation and absence of methionine selectivity. Journal of Medicinal Chemistry. 49: 2200-9. PMID 16570916 DOI: 10.1021/Jm050958A |
0.823 |
|
| 2006 |
Leclerc PC, Lanctot PM, Auger-Messier M, Escher E, Leduc R, Guillemette G. S-nitrosylation of cysteine 289 of the AT1 receptor decreases its binding affinity for angiotensin II. British Journal of Pharmacology. 148: 306-13. PMID 16565729 DOI: 10.1038/Sj.Bjp.0706725 |
0.553 |
|
| 2006 |
Lanctôt PM, Leclerc PC, Escher E, Guillemette G, Leduc R. Role of N-glycan-dependent quality control in the cell-surface expression of the AT1 receptor. Biochemical and Biophysical Research Communications. 340: 395-402. PMID 16364240 DOI: 10.1016/J.Bbrc.2005.12.016 |
0.473 |
|
| 2005 |
Kraetke O, Holeran B, Berger H, Escher E, Bienert M, Beyermann M. Photoaffinity cross-linking of the corticotropin-releasing factor receptor type 1 with photoreactive urocortin analogues. Biochemistry. 44: 15569-77. PMID 16300406 DOI: 10.1021/Bi0507027 |
0.582 |
|
| 2005 |
Auger-Messier M, Turgeon ES, Leduc R, Escher E, Guillemette G. The constitutively active N111G-AT1 receptor for angiotensin II modifies the morphology and cytoskeletal organization of HEK-293 cells. Experimental Cell Research. 308: 188-95. PMID 15896777 DOI: 10.1016/J.Yexcr.2005.04.015 |
0.492 |
|
| 2005 |
Clément M, Martin SS, Beaulieu ME, Chamberland C, Lavigne P, Leduc R, Guillemette G, Escher E. Determining the environment of the ligand binding pocket of the human angiotensin II type I (hAT1) receptor using the methionine proximity assay. The Journal of Biological Chemistry. 280: 27121-9. PMID 15890659 DOI: 10.1074/Jbc.M413653200 |
0.558 |
|
| 2005 |
Lanctot PM, Leclerc PC, Clément M, Auger-Messier M, Escher E, Leduc R, Guillemette G. Importance of N-glycosylation positioning for cell-surface expression, targeting, affinity and quality control of the human AT1 receptor. The Biochemical Journal. 390: 367-76. PMID 15869468 DOI: 10.1042/Bj20050189 |
0.514 |
|
| 2005 |
Proulx CD, Simaan M, Escher E, Laporte SA, Guillemette G, Leduc R. Involvement of a cytoplasmic-tail serine cluster in urotensin II receptor internalization. The Biochemical Journal. 385: 115-23. PMID 15458389 DOI: 10.1042/Bj20040807 |
0.593 |
|
| 2004 |
Martin SS, Boucard AA, Clément M, Escher E, Leduc R, Guillemette G. Analysis of the third transmembrane domain of the human type 1 angiotensin II receptor by cysteine scanning mutagenesis. The Journal of Biological Chemistry. 279: 51415-23. PMID 15452107 DOI: 10.1074/Jbc.M407965200 |
0.617 |
|
| 2004 |
Auger-Messier M, Arguin G, Chaloux B, Leduc R, Escher E, Guillemette G. Down-regulation of inositol 1,4,5-trisphosphate receptor in cells stably expressing the constitutively active angiotensin II N111G-AT(1) receptor. Molecular Endocrinology (Baltimore, Md.). 18: 2967-80. PMID 15331757 DOI: 10.1210/Me.2003-0488 |
0.403 |
|
| 2003 |
Auger-Messier M, Clement M, Lanctot PM, Leclerc PC, Leduc R, Escher E, Guillemette G. The constitutively active N111G-AT1 receptor for angiotensin II maintains a high affinity conformation despite being uncoupled from its cognate G protein Gq/11alpha. Endocrinology. 144: 5277-84. PMID 12960024 DOI: 10.1210/En.2003-0677 |
0.582 |
|
| 2003 |
Boucard AA, Roy M, Beaulieu ME, Lavigne P, Escher E, Guillemette G, Leduc R. Constitutive activation of the angiotensin II type 1 receptor alters the spatial proximity of transmembrane 7 to the ligand-binding pocket. The Journal of Biological Chemistry. 278: 36628-36. PMID 12842881 DOI: 10.1074/Jbc.M305952200 |
0.603 |
|
| 2003 |
Boucard AA, Sauvé SS, Guillemette G, Escher E, Leduc R. Photolabelling the rat urotensin II/GPR14 receptor identifies a ligand-binding site in the fourth transmembrane domain. The Biochemical Journal. 370: 829-38. PMID 12495432 DOI: 10.1042/Bj20021566 |
0.594 |
|
| 2002 |
Rihakova L, Deraët M, Auger-Messier M, Pérodin J, Boucard AA, Guillemette G, Leduc R, Lavigne P, Escher E. Methionine proximity assay, a novel method for exploring peptide ligand-receptor interaction. Journal of Receptor and Signal Transduction Research. 22: 297-313. PMID 12503623 DOI: 10.1081/Rrs-120014603 |
0.769 |
|
| 2002 |
Pérodin J, Deraët M, Auger-Messier M, Boucard AA, Rihakova L, Beaulieu ME, Lavigne P, Parent JL, Guillemette G, Leduc R, Escher E. Residues 293 and 294 are ligand contact points of the human angiotensin type 1 receptor. Biochemistry. 41: 14348-56. PMID 12450401 DOI: 10.1021/Bi0258602 |
0.835 |
|
| 2002 |
Leclerc PC, Auger-Messier M, Lanctot PM, Escher E, Leduc R, Guillemette G. A polyaromatic caveolin-binding-like motif in the cytoplasmic tail of the type 1 receptor for angiotensin II plays an important role in receptor trafficking and signaling. Endocrinology. 143: 4702-10. PMID 12446598 DOI: 10.1210/En.2002-220679 |
0.587 |
|
| 2002 |
Deraët M, Rihakova L, Boucard A, Pèrodin J, Sauvé S, Mathieu AP, Guillemette G, Leduc R, Lavigne P, Escher E. Angiotensin II is bound to both receptors AT1 and AT2, parallel to the transmembrane domains and in an extended form. Canadian Journal of Physiology and Pharmacology. 80: 418-25. PMID 12056548 DOI: 10.1139/Y02-060 |
0.77 |
|
| 2001 |
Pérodin J, Boucard AA, Leduc R, Escher E, Guillemette G. Assays for radiolabel-photoaffinity labeling of Angiotensin receptors. Methods in Molecular Medicine. 51: 297-303. PMID 21331725 DOI: 10.1385/1-59259-087-X:297 |
0.81 |
|
| 2000 |
Boucard AA, Wilkes BC, Laporte SA, Escher E, Guillemette G, Leduc R. Photolabeling identifies position 172 of the human AT(1) receptor as a ligand contact point: receptor-bound angiotensin II adopts an extended structure. Biochemistry. 39: 9662-70. PMID 10933782 DOI: 10.1021/Bi000597V |
0.642 |
|
| 2000 |
Pérodin J, Bouley R, Escher E, Assimomytis N, Magafa V, Manessi-Zoupa E, Theodoropoulos D, Cordopatis P. Angiotensin II analogues with sulphur-containing side-chains in position 5. A structure-activity relationship study. Arzneimittel-Forschung. 50: 526-9. PMID 10918944 DOI: 10.1055/S-0031-1300242 |
0.808 |
|
| 2000 |
Gosselin MJ, Leclerc PC, Auger-Messier M, Guillemette G, Escher E, Leduc R. Molecular cloning of a ferret angiotensin II AT(1) receptor reveals the importance of position 163 for Losartan binding. Biochimica Et Biophysica Acta. 1497: 94-102. PMID 10838163 DOI: 10.1016/S0167-4889(00)00046-X |
0.616 |
|
| 1999 |
Lanctôt PM, Leclerc PC, Escher E, Leduc R, Guillemette G. Role of N-glycosylation in the expression and functional properties of human AT1 receptor. Biochemistry. 38: 8621-7. PMID 10393537 DOI: 10.1021/Bi9830516 |
0.555 |
|
| 1999 |
Laporte SA, Boucard AA, Servant G, Guillemette G, Leduc R, Escher E. Determination of peptide contact points in the human angiotensin II type I receptor (AT1) with photosensitive analogs of angiotensin II. Molecular Endocrinology (Baltimore, Md.). 13: 578-86. PMID 10194764 DOI: 10.1210/Mend.13.4.0270 |
0.619 |
|
| 1998 |
Bouley R, Pérodin J, Plante H, Řihakova L, Bernier SG, Maletínská L, Guillemette G, Escher E. N- and C-terminal structure-activity study of angiotensin II on the angiotensin AT2 receptor European Journal of Pharmacology. 343: 323-331. PMID 9570482 DOI: 10.1016/S0014-2999(97)01549-5 |
0.826 |
|
| 1998 |
Servant G, Escher E, Guillemette G. The angiotensin II binding site on Mycoplasma hyorhynis is structurally distinct from mammalian AT1 and AT2 receptors. Regulatory Peptides. 73: 35-41. PMID 9537671 DOI: 10.1016/S0167-0115(97)01060-4 |
0.497 |
|
| 1998 |
Bernier SG, Bellemare JM, Escher E, Guillemette G. Characterization of AT4 receptor from bovine aortic endothelium with photosensitive analogues of angiotensin IV Biochemistry. 37: 4280-4287. PMID 9521751 DOI: 10.1021/Bi972863J |
0.542 |
|
| 1998 |
Ong H, McNicoll N, Escher E, Collu R, Deghenghi R, Locatelli V, Ghigo E, Muccioli G, Boghen M, Nilsson M. Identification of a pituitary growth hormone-releasing peptide (GHRP) receptor subtype by photoaffinity labeling. Endocrinology. 139: 432-5. PMID 9421445 DOI: 10.1210/Endo.139.1.5811 |
0.481 |
|
| 1997 |
Kumar U, Laird D, Srikant CB, Escher E, Patel YC. Expression of the Five Somatostatin Receptor (SSTR1-5) Subtypes in Rat Pituitary Somatotrophes: Quantitative Analysis by Double-Label Immunofluorescence Confocal Microscopy. Endocrinology. 138: 4473-4476. PMID 28200134 DOI: 10.1210/endo.138.10.5566 |
0.303 |
|
| 1997 |
Maletínská L, Neugebauer W, Pérodin J, Lefebvre M, Escher E. Angiotensin analogues palmitoylated in positions 1 and 4. Journal of Medicinal Chemistry. 40: 3271-9. PMID 9379447 DOI: 10.1021/Jm9608669 |
0.812 |
|
| 1997 |
Chrétien L, Laporte SA, Escher E, Leduc R, Guillemette G. Use of LiCl in phospholipase C assays masks the impaired functionality of a mutant angiotensin II receptor. Cellular Signalling. 9: 379-82. PMID 9376218 DOI: 10.1016/S0898-6568(97)00032-6 |
0.53 |
|
| 1997 |
Bouley R, Gosselin M, Plante H, Servant G, Pérodin J, Arcand M, Guillemette G, Escher E. Characterization of a specific binding site for angiotensin II in chicken liver. Canadian Journal of Physiology and Pharmacology. 75: 568-75. PMID 9276130 DOI: 10.1139/Cjpp-75-6-568 |
0.784 |
|
| 1997 |
Lacasse FX, Hildgen P, Pérodin J, Escher E, Phillips NC, McMullen JN. Improved activity of a new angiotensin receptor antagonist by an injectable spray-dried polymer microsphere preparation. Pharmaceutical Research. 14: 887-91. PMID 9244145 DOI: 10.1023/A:1012147700014 |
0.762 |
|
| 1997 |
Servant G, Laporte SA, Leduc R, Escher E, Guillemette G. Identification of angiotensin II-binding domains in the rat AT2 receptor with photolabile angiotensin analogs. The Journal of Biological Chemistry. 272: 8653-9. PMID 9079697 DOI: 10.1074/Jbc.272.13.8653 |
0.538 |
|
| 1996 |
Pham D, Laporte S, Pérodin J, Bourgeois R, Escher E. What can angiotensin antagonists do that converting-enzyme inhibition can't: the case of post-angioplastic restenosis. Canadian Journal of Physiology and Pharmacology. 74: 867-77. PMID 8946074 |
0.434 |
|
| 1996 |
Barbeau D, Bouley R, Escher E. Molecular weight determination of the hepatic vasopressin receptor with a high-affinity photoprobe International Journal of Peptide and Protein Research. 48: 364-373. PMID 8919057 DOI: 10.1111/J.1399-3011.1996.Tb00853.X |
0.505 |
|
| 1996 |
Parent JL, Gouill CL, Escher E, Rola-Pleszczynski M, Staková J. Identification of transmembrane domain residues determinant in the structure-function relationship of the human platelet-activating factor receptor by site-directed mutagenesis. The Journal of Biological Chemistry. 271: 23298-303. PMID 8798529 DOI: 10.1074/Jbc.271.38.23298 |
0.594 |
|
| 1996 |
Pérodin J, Bossé R, Gagnon S, Zhou LM, Bouley R, Leduc R, Escher E. Structure-activity relationship of the agonist-antagonist transition on the type 1 angiotensin II receptor; the search for inverse agonists. Advances in Experimental Medicine and Biology. 396: 131-43. PMID 8726693 DOI: 10.1007/978-1-4899-1376-0_14 |
0.851 |
|
| 1996 |
Zhang WJ, Nikiforovich GV, Pérodin J, Richard DE, Escher E, Marshall GR. Novel cyclic analogs of angiotensin II with cyclization between positions 5 and 7: conformational and biological implications. Journal of Medicinal Chemistry. 39: 2738-44. PMID 8709104 DOI: 10.1021/Jm9507744 |
0.831 |
|
| 1996 |
Servant G, Dudley DT, Escher E, Guillemette G. Analysis of the role of N-glycosylation in cell-surface expression and binding properties of angiotensin II type-2 receptor of rat pheochromocytoma cells. The Biochemical Journal. 297-304. PMID 8546698 DOI: 10.1042/Bj3130297 |
0.568 |
|
| 1995 |
Cordopatis P, Manessi-Zoupa E, Theodoropoulos D, Bossé R, Bouley R, Gagnon S, Escher E. Methylation in positions 1 and 7 of angiotensin II. A structure-activity relationship study. International Journal of Peptide and Protein Research. 44: 320-4. PMID 7875933 DOI: 10.1111/J.1399-3011.1994.Tb01015.X |
0.453 |
|
| 1993 |
Bossé R, Servant G, Zhou LM, Boulay G, Guillemette G, Escher E. Sar1-p-benzoylphenylalanine-angiotensin, a new photoaffinity probe for selective labeling of the type 2 angiotensin receptor. Regulatory Peptides. 44: 215-23. PMID 8469775 DOI: 10.1016/0167-0115(93)90245-4 |
0.571 |
|
| 1993 |
Dagenais P, Escher E. Anti-angiotensin antibodies cross-reactive with nonpeptide angiotensin antagonists as angiotensin receptor model. Regulatory Peptides. 44: 239-47. PMID 8385792 DOI: 10.1016/0167-0115(93)90248-7 |
0.512 |
|
| 1993 |
Paré MC, Maltais S, Escher E. The neurogenic origin of hypertension in SHR may be mediated by angiotensin II through a receptor different from AT1 and AT2. Regulatory Peptides. 47: 81-6. PMID 8210522 DOI: 10.1016/0167-0115(93)90275-D |
0.52 |
|
| 1992 |
Barbeau D, Guay S, Neugebauer W, Escher E. Preparation and biological activities of potential vasopressin photoaffinity labels Journal of Medicinal Chemistry. 35: 151-157. PMID 1732523 DOI: 10.1021/Jm00079A020 |
0.498 |
|
| 1992 |
Guillon G, Barbeau D, Neugebauer W, Guay S, Bilodeau L, Balestre MN, Gallo-Payet N, Escher E. Fluorescent peptide hormones: Development of high affinity vasopressin analogues Peptides. 13: 7-11. PMID 1535709 DOI: 10.1016/0196-9781(92)90133-N |
0.473 |
|
| 1992 |
Laporte S, Escher E. Neointima formation after vascular injury is angiotensin II mediated. Biochemical and Biophysical Research Communications. 187: 1510-6. PMID 1417827 DOI: 10.1016/0006-291X(92)90473-X |
0.393 |
|
| 1992 |
McNicoll N, Escher E, Wilkes BC, Schiller PW, Ong H, De Léan A. Highly efficient photoaffinity labeling of the hormone binding domain of atrial natriuretic factor receptor. Biochemistry. 31: 4487-93. PMID 1316147 DOI: 10.1021/Bi00133A015 |
0.61 |
|
| 1991 |
Bossé R, Gerold M, Fischli W, Holck M, Escher E. An angiotensin with prolonged action and blood pressure--lowering properties. Journal of Cardiovascular Pharmacology. S50-5. PMID 1705628 DOI: 10.1097/00005344-199016004-00011 |
0.517 |
|
| 1990 |
Rondeau J-, Mcnicoll N, Escher E, Meloche S, Ong H, Lean AD. Hydrodynamic properties of the angiotensin II receptor from bovine adrenal zona glomerulosa. Biochemical Journal. 268: 443-448. PMID 2363683 DOI: 10.1042/Bj2680443 |
0.564 |
|
| 1990 |
Larose L, McNicoll N, Rondeau JJ, Escher E, Lean AD. Photoaffinity labelling of atrial natriuretic factor (ANF)-R1 receptor by underivatized 125I-ANF. Involvement of lipid peroxidation. Biochemical Journal. 267: 379-384. PMID 2159278 DOI: 10.1042/Bj2670379 |
0.523 |
|
| 1990 |
Dam TV, Escher E, Quirion R. Visualization of neurokinin-3 receptor sites in rat brain using the highly selective ligand [3H]senktide. Brain Research. 506: 175-9. PMID 1689199 DOI: 10.1016/0006-8993(90)91218-6 |
0.426 |
|
| 1990 |
Dam TV, Takeda Y, Krause JE, Escher E, Quirion R. gamma-Preprotachykinin-(72-92)-peptide amide: an endogenous preprotachykinin I gene-derived peptide that preferentially binds to neurokinin-2 receptors. Proceedings of the National Academy of Sciences of the United States of America. 87: 246-50. PMID 1688655 DOI: 10.1073/Pnas.87.1.246 |
0.526 |
|
| 1989 |
Guillemette G, Boulay G, Gagnon S, Bosse R, Escher E. The peptide encoded by angiotensin II complementary RNA does not interfere with angiotensin II action. The Biochemical Journal. 261: 309. PMID 2775218 DOI: 10.1042/Bj2610309 |
0.395 |
|
| 1989 |
Holck M, Bossé R, Fischli W, Gerold H, Escher E. An angiotensin II antagonist with strongly prolonged action. Biochemical and Biophysical Research Communications. 160: 1350-6. PMID 2730646 DOI: 10.1016/S0006-291X(89)80152-4 |
0.312 |
|
| 1989 |
Neugebauer W, Escher E. Solid-phase Synthesis of C-Terminal Peptide Amino Alcohols Helvetica Chimica Acta. 72: 1319-1323. DOI: 10.1002/Hlca.19890720620 |
0.314 |
|
| 1988 |
Dam TV, Escher E, Quirion R. Evidence for the existence of three classes of neurokinin receptors in brain. Differential ontogeny of neurokinin-1, neurokinin-2 and neurokinin-3 binding sites in rat cerebral cortex. Brain Research. 453: 372-6. PMID 2456834 DOI: 10.1016/0006-8993(88)90181-3 |
0.438 |
|
| 1988 |
Cordopatis P, Belté U, Theodoropoulos D, Bossé R, Escher E. The influence of certain substitutions on 1 and 2 positions of angiotensin II on biological responses Collection of Czechoslovak Chemical Communications. 53: 2599-2603. DOI: 10.1135/Cccc19882599 |
0.377 |
|
| 1987 |
Bodenmüller H, Escher E, Zachmann B, Schilling E. Synthesis of new head-activator analogues and their application for improved radioimmunoassays. International Journal of Peptide and Protein Research. 29: 140-4. PMID 3570652 DOI: 10.1111/J.1399-3011.1987.Tb02240.X |
0.335 |
|
| 1987 |
Mackiewicz Z, Bélisle S, Bellabarba D, Gallo-Payet N, Lehoux J, Lagacé G, Escher E. Synthesis and Placental Binding Potencies of Photosensitive Analogues of Luteinizing Hormone Releasing Hormone (LHRH) with Agonistic and Antagonistic Structures Helvetica Chimica Acta. 70: 423-429. DOI: 10.1002/Hlca.19870700221 |
0.492 |
|
| 1986 |
Mizrahi J, Dion S, D'Orléans-Juste P, Escher E, Drapeau G, Regoli D. Tachykinin receptors in smooth muscles: a study with agonists (substance P, neurokinin A) and antagonists. European Journal of Pharmacology. 118: 25-36. PMID 2417867 DOI: 10.1016/0014-2999(85)90659-4 |
0.443 |
|
| 1986 |
THEODOROPOULOS D, POULOS C, GATOS D, CORDOPATIS P, ESCHER E, MIZRAHI J, REGOLI D, DALIETOS D, FURST A, LEE TD. ChemInform Abstract: Conformationally Restricted C-Terminal Peptides of Substance P. Chemischer Informationsdienst. 17. DOI: 10.1002/Chin.198606292 |
0.329 |
|
| 1985 |
Escher E, D'Orléans-Juste P, Dion S, Drapeau G, Mizrahi J, Regoli D. A substance P antagonist not containing D-tryptophan. European Journal of Pharmacology. 105: 375-7. PMID 6210204 DOI: 10.1016/0014-2999(84)90636-8 |
0.308 |
|
| 1985 |
Gallo-Payet N, Escher E. Adrenocorticotropin receptors in rat adrenal glomerulosa cells Endocrinology. 117: 38-46. PMID 2988924 DOI: 10.1210/Endo-117-1-38 |
0.363 |
|
| 1985 |
Regoli D, Mizrahi J, D'Orléans-Juste P, Dion S, Drapeau G, Escher E. Substance P antagonists showing some selectivity for different receptor types. European Journal of Pharmacology. 109: 121-5. PMID 2581793 DOI: 10.1016/0014-2999(85)90548-5 |
0.392 |
|
| 1985 |
Theodoropoulos D, Poulos C, Gatos D, Cordopatis P, Escher E, Mizrahi J, Regoli D, Dalietos D, Furst A, Lee TD. Conformationally restricted C-terminal peptides of substance P. Synthesis, mass spectral analysis and pharmacological properties. Journal of Medicinal Chemistry. 28: 1536-9. PMID 2413208 DOI: 10.1021/Jm00148A029 |
0.392 |
|
| 1985 |
Mathison R, Escher E, Huggel H, Mizrahi J, Regoli D. Tachykinin antagonists: substitutions in positions 5 and 6 with amino acids from the primary sequence of substance P homologues. European Journal of Pharmacology. 114: 147-55. PMID 2412854 DOI: 10.1016/0014-2999(85)90622-3 |
0.451 |
|
| 1984 |
Guillemette G, Bernier M, Parent P, Leduc R, Escher E. Angiotensin II: dependence of hormone affinity on the electronegativity of a single side chain. Journal of Medicinal Chemistry. 27: 315-20. PMID 6699877 DOI: 10.1002/Chin.198432338 |
0.45 |
|
| 1984 |
Guillemette G, Escher E. Analysis of the adrenal angiotensin II receptor with the photoaffinity labeling method. Biochemistry. 22: 5591-6. PMID 6317023 DOI: 10.1021/Bi00293A021 |
0.563 |
|
| 1984 |
Mizrahi J, Escher E, D'Orléans-Juste P, Regoli D. Undeca- and octa-peptide antagonists for substance P, a study on the guinea pig trachea. European Journal of Pharmacology. 99: 193-202. PMID 6203766 DOI: 10.1016/0014-2999(84)90241-3 |
0.488 |
|
| 1984 |
Regoli D, Escher E, Mizrahi J. Substance P--structure-activity studies and the development of antagonists. Pharmacology. 28: 301-20. PMID 6203130 DOI: 10.1159/000137979 |
0.453 |
|
| 1984 |
Mizrahi J, D'Orléans-Juste P, Drapeau G, Escher E, Regoli D. Partial agonists and antagonists for substance P. European Journal of Pharmacology. 98: 457-8. PMID 6202534 DOI: 10.1016/0014-2999(84)90301-7 |
0.384 |
|
| 1984 |
Regoli D, Escher E, Drapeau G, D'Orléans-Juste P, Mizrahi J. Receptors for substance P. III. Classification by competitive antagonists. European Journal of Pharmacology. 97: 179-89. PMID 6200337 DOI: 10.1016/0014-2999(84)90449-7 |
0.448 |
|
| 1984 |
Regoli D, Mizrahi J, D'Orléans-Juste P, Escher E. Receptors for substance P. II. Classification by agonist fragments and homologues. European Journal of Pharmacology. 97: 171-7. PMID 6200336 DOI: 10.1016/0014-2999(84)90448-5 |
0.349 |
|
| 1983 |
Mizrahi J, D'Orléans-Juste P, Drapeau G, Escher E, Regoli D. Partial agonists and antagonists for substance P. European Journal of Pharmacology. 91: 139-40. PMID 6193969 DOI: 10.1016/0014-2999(83)90376-X |
0.384 |
|
| 1983 |
Escher E, Couture R, Poulos C, Pinas N, Mizrahi J, Theodoropoulos D, Regoli D. Structure-activity studies on the C-terminal amide of substance P. Journal of Medicinal Chemistry. 25: 1317-21. PMID 6183431 DOI: 10.1002/Chin.198317341 |
0.357 |
|
| 1983 |
Caranikas S, Mizrahi J, Escher E, Regoli D. Synthesis and biological activities of substance P antagonists. Journal of Medicinal Chemistry. 25: 1313-6. PMID 6183430 DOI: 10.1002/Chin.198317317 |
0.354 |
|
| 1983 |
Escher E, Bernier M, Parent P. Angiotensin II Analogues. Part II. Synthesis and incorporation of the sulfur-containing aromatic amino acids:L-(4?-SH)Phe,L-(4?-SO2NH2)Phe,L-(4?-SO3?)Phe andL-(4?-S-CH3)Phe Helvetica Chimica Acta. 66: 1355-1365. DOI: 10.1002/Hlca.19830660504 |
0.393 |
|
| 1983 |
Escher E, Bernier M, Parent P. Angiotensin Ii Analogs. Part Ii. Synthesis And Incorporation Of The Sulfur-Containing Aromatic Amino Acids: L-(4′-Sh)Phe, L-(4′-So2Nh2)Phe, L-(4′-So3-)Phe And L-(4′-Sch3)Phe Cheminform. 14. DOI: 10.1002/Chin.198344321 |
0.35 |
|
| 1982 |
Mizrahi J, Escher E, Caranikas S, D'orléans-Juste P, Regoli D. Substance P antagonists active in vitro and in vivo. European Journal of Pharmacology. 82: 101-5. PMID 6182006 DOI: 10.1016/0014-2999(82)90561-1 |
0.33 |
|
| 1982 |
Escher E, Couture R, Champagne G, Mizrahi J, Regoli D. Synthesis and biological activities of photoaffinity labeling analogues of substance P. Journal of Medicinal Chemistry. 25: 470-5. PMID 6175752 DOI: 10.1002/Chin.198235301 |
0.439 |
|
| 1982 |
Escher E, Laczkó E, Guillemette G, Regoli D. Biological activities of photoaffinity labeling analogues of kinins and their irreversible effects on kinin receptors. Journal of Medicinal Chemistry. 24: 1409-13. PMID 6118437 DOI: 10.1002/Chin.198221327 |
0.527 |
|
| 1981 |
Cordopatis P, Theodoropoulos D, Guillemette G, Escher E. Studies on position 1 of angiotensin II: effects on affinity and duration of action from alkyl amide substitution. Journal of Medicinal Chemistry. 24: 209-11. PMID 7205889 DOI: 10.1002/Chin.198128367 |
0.427 |
|
| 1980 |
Escher E, Guillemette G, Leukart O, Regoli D. Pharmacological properties of two analogues of angiotensin II containing carboranylalanine (Car). European Journal of Pharmacology. 66: 267-72. PMID 7418720 DOI: 10.1016/0014-2999(80)90458-6 |
0.552 |
|
| 1979 |
Leukart O, Escher E, Regoli D, Schwyzer R. Synthesis of angiotensins, bradykinins and substance P octapeptides in which the residues Phe and Tyr have been replaced with car and of [Car1, Leu5]-enkephalin Helvetica Chimica Acta. 62: 546-552. DOI: 10.1002/Chin.197922325 |
0.433 |
|
| 1976 |
Fischli W, Caviezel M, Eberle A, Escher E, Schwyzer R. [The synthesis of 4'-azido-3',5'-ditritio-l-phenylalanine peptides as "photo-affinity probes" for ligand-receptor interaction (author's transl)]. Helvetica Chimica Acta. 59: 878-9. PMID 1262224 DOI: 10.1002/Hlca.19760590317 |
0.474 |
|
| 1976 |
FISCHLI W, CAVIEZEL M, EBERLE A, ESCHER E, SCHWYZER R. ChemInform Abstract: SYNTHESIS OF 4′-AZIDO-3′,5′-DITRITIO-L-PHENYLALANINE PEPTIDES AS ′PHOTOAFFINITY PROBES′ FOR LIGAND-RECEPTOR INTERACTION Chemischer Informationsdienst. 7: no-no. DOI: 10.1002/Chin.197626148 |
0.467 |
|
| 1975 |
Escher E, Schwyzer R. [Photoaffinity labelling of chymotrypsin. Synthesis of photorecognizable ligands]. Helvetica Chimica Acta. 58: 1465-71. PMID 1158751 DOI: 10.1002/Hlca.19750580524 |
0.317 |
|
| 1975 |
Escher E, Jost R, Zuber H, Schwyzer R. P‐Azido‐L‐Phenylalanine Peptides Part 1, Synthesis Of Peptide Ligands For Chymotrypsin And Aminopeptidases Cheminform. 6. DOI: 10.1002/Chin.197509437 |
0.413 |
|
| 1974 |
Escher E, Jost R, Zuber H, Schwyzer R. p-Azido-L-Phenylalanine Peptides. I: Synthesis of Peptide Ligands for Chymotrypsin and Aminopeptidases Israel Journal of Chemistry. 12: 129-138. DOI: 10.1002/Ijch.197400013 |
0.33 |
|
| Show low-probability matches. |