| Year |
Citation |
Score |
| 2024 |
Scherlinger M, Li H, Pan W, Li W, Karino K, Vichos T, Boulougoura A, Yoshida N, Tsokos MG, Tsokos GC. CaMK4 controls follicular helper T cell expansion and function during normal and autoimmune T-dependent B cell responses. Nature Communications. 15: 840. PMID 38287012 DOI: 10.1038/s41467-024-45080-x |
0.339 |
|
| 2022 |
Scherlinger M, Pan W, Hisada R, Boulougoura A, Yoshida N, Vukelic M, Umeda M, Krishfield S, Tsokos MG, Tsokos GC. Phosphofructokinase P fine-tunes T regulatory cell metabolism, function, and stability in systemic autoimmunity. Science Advances. 8: eadc9657. PMID 36449620 DOI: 10.1126/sciadv.adc9657 |
0.301 |
|
| 2022 |
Li H, Boulougoura A, Endo Y, Tsokos GC. Abnormalities of T cells in systemic lupus erythematosus: new insights in pathogenesis and therapeutic strategies. Journal of Autoimmunity. 102870. PMID 35872102 DOI: 10.1016/j.jaut.2022.102870 |
0.358 |
|
| 2022 |
Koga T, Umeda M, Yoshida N, Satyam A, Jha M, Scherlinger M, Bhargava R, Tsokos MG, Sato T, Furukawa K, Endo Y, Fukui S, Iwamoto N, Abiru N, Okita M, ... ... Tsokos GC, et al. Inhibition of calcium/calmodulin-dependent protein kinase IV in arthritis: Dual effect on Th17 cell activation and osteoclastogenesis. Rheumatology (Oxford, England). PMID 35781320 DOI: 10.1093/rheumatology/keac381 |
0.676 |
|
| 2022 |
Chen PM, Katsuyama E, Satyam A, Li H, Rubio J, Jung S, Andrzejewski S, Becherer JD, Tsokos MG, Abdi R, Tsokos GC. CD38 reduces mitochondrial fitness and cytotoxic T cell response against viral infection in lupus patients by suppressing mitophagy. Science Advances. 8: eabo4271. PMID 35704572 DOI: 10.1126/sciadv.abo4271 |
0.698 |
|
| 2022 |
Hisada R, Yoshida N, Umeda M, Burbano C, Bhargava R, Scherlinger M, Kono M, Kyttaris VC, Krishfield S, Tsokos GC. The deacetylase SIRT2 contributes to autoimmune disease pathogenesis by modulating IL-17A and IL-2 transcription. Cellular & Molecular Immunology. 19: 738-750. PMID 35523941 DOI: 10.1038/s41423-022-00874-1 |
0.307 |
|
| 2022 |
Morita M, Mizui M, Masuyama S, Tsokos GC, Isaka Y. Reduction of Cell Surface T-Cell Receptor by Non-Mitogenic CD3 Antibody to Mitigate Murine Lupus. Frontiers in Immunology. 13: 855812. PMID 35419004 DOI: 10.3389/fimmu.2022.855812 |
0.31 |
|
| 2022 |
Satyam A, Hisada R, Bhargava R, Tsokos MG, Tsokos GC. Intertwined pathways of complement activation command the pathogenesis of lupus nephritis. Translational Research : the Journal of Laboratory and Clinical Medicine. PMID 35296451 DOI: 10.1016/j.trsl.2022.03.005 |
0.697 |
|
| 2021 |
Jamaly S, Tsokos MG, Bhargava R, Brook OR, Hecht JL, Abdi R, Moulton VR, Satyam A, Tsokos GC. Complement activation and increased expression of Syk, mucin-1 and CaMK4 in kidneys of patients with COVID-19. Clinical Immunology (Orlando, Fla.). 229: 108795. PMID 34252574 DOI: 10.1016/j.clim.2021.108795 |
0.69 |
|
| 2021 |
Chen PM, Tsokos GC. The role of CD8+ T-cell systemic lupus erythematosus pathogenesis: an update. Current Opinion in Rheumatology. 33: 586-591. PMID 34183542 DOI: 10.1097/BOR.0000000000000815 |
0.331 |
|
| 2021 |
Satyam A, Tsokos MG, Brook OR, Hecht JL, Moulton VR, Tsokos GC. Activation of classical and alternative complement pathways in the pathogenesis of lung injury in COVID-19. Clinical Immunology (Orlando, Fla.). 226: 108716. PMID 33774179 DOI: 10.1016/j.clim.2021.108716 |
0.663 |
|
| 2021 |
Pan W, Nagpal K, Suárez-Fueyo A, Ferretti A, Yoshida N, Tsokos MG, Tsokos GC. The Regulatory Subunit PPP2R2A of PP2A Enhances Th1 and Th17 Differentiation through Activation of the GEF-H1/RhoA/ROCK Signaling Pathway. Journal of Immunology (Baltimore, Md. : 1950). PMID 33762326 DOI: 10.4049/jimmunol.2001266 |
0.304 |
|
| 2021 |
Chen PM, Tsokos GC. T Cell Abnormalities in the Pathogenesis of Systemic Lupus Erythematosus: an Update. Current Rheumatology Reports. 23: 12. PMID 33512577 DOI: 10.1007/s11926-020-00978-5 |
0.313 |
|
| 2020 |
Satyam A, Tsokos MG, Tresback JS, Zeugolis DI, Tsokos GC. Cell‐Derived Extracellular Matrix‐Rich Biomimetic Substrate Supports Podocyte Proliferation, Differentiation, and Maintenance of Native Phenotype Advanced Functional Materials. 30. PMID 33692659 DOI: 10.1002/Adfm.201908752 |
0.741 |
|
| 2020 |
Kost-Alimova M, Sidhom EH, Satyam A, Chamberlain BT, Dvela-Levitt M, Melanson M, Alper SL, Santos J, Gutierrez J, Subramanian A, Byrne PJ, Grinkevich E, Reyes-Bricio E, Kim C, Clark AR, ... ... Tsokos GC, et al. A High-Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury. Cell Reports. Medicine. 1: 100137. PMID 33294858 DOI: 10.1016/j.xcrm.2020.100137 |
0.668 |
|
| 2020 |
Satyam A, Tsokos GC. Curb complement to cure COVID-19. Clinical Immunology (Orlando, Fla.). 221: 108603. PMID 33022386 DOI: 10.1016/j.clim.2020.108603 |
0.644 |
|
| 2020 |
Pan W, Sharabi A, Ferretti AP, Zhang Y, Burbano C, Yoshida N, Tsokos MG, Tsokos GC. PPP2R2D suppresses interleukin-2 production and regulatory T cell function. Jci Insight. PMID 32897879 DOI: 10.1172/Jci.Insight.138215 |
0.421 |
|
| 2020 |
Tsokos GC, Terhorst C. T Lymphocytes Cash Their Value in Clinical Medicine. Trends in Molecular Medicine. 26: 800-802. PMID 32857968 DOI: 10.1016/J.Molmed.2020.06.003 |
0.389 |
|
| 2020 |
Rodríguez-Rodríguez N, Madera-Salcedo IK, Cisneros-Segura JA, García-González HB, Apostolidis SA, Saint-Martin A, Esquivel-Velázquez M, Nguyen T, Romero-Rodríguez DP, Tsokos GC, Alcocer-Varela J, Rosetti F, Crispin JC. Protein phosphatase 2A B55ß limits CD8 T cell lifespan following cytokine withdrawal. The Journal of Clinical Investigation. PMID 32750040 DOI: 10.1172/Jci129479 |
0.395 |
|
| 2020 |
Alimova M, Sidhom EH, Satyam A, Dvela-Levitt M, Melanson M, Chamberlain BT, Alper SL, Santos J, Gutierrez J, Subramanian A, Grinkevich E, Bricio ER, Kim C, Clark A, Watts A, ... ... Tsokos GC, et al. A High Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury during the COVID-19 pandemic. Biorxiv : the Preprint Server For Biology. PMID 32637960 DOI: 10.1101/2020.06.30.180380 |
0.676 |
|
| 2020 |
Bhargava R, Maeda K, Tsokos MG, Pavlakis M, Stillman IE, Tsokos GC. N‐glycosylated IgG in patients with kidney transplants increases calcium/calmodulin kinase IV in podocytes and causes injury American Journal of Transplantation. 21: 148-160. PMID 32531122 DOI: 10.1111/Ajt.16140 |
0.302 |
|
| 2020 |
Li H, Adamopoulos IE, Moulton VR, Stillman IE, Herbert Z, Moon JJ, Sharabi A, Krishfield S, Tsokos MG, Tsokos GC. Systemic lupus erythematosus favors the generation of IL-17 producing double negative T cells. Nature Communications. 11: 2859. PMID 32503973 DOI: 10.1038/S41467-020-16636-4 |
0.445 |
|
| 2020 |
Tsokos GC. Autoimmunity and organ damage in systemic lupus erythematosus. Nature Immunology. 21: 605-614. PMID 32367037 DOI: 10.1038/S41590-020-0677-6 |
0.352 |
|
| 2020 |
Meidan E, Li H, Pan W, Kono M, Yu S, Kyttaris VC, Ioannidis C, Rodriguez Rodriguez N, Crispin JC, Apostolidis SA, Lee P, Manis J, Sharabi A, Tsokos MG, Tsokos GC. Serine/threonine phosphatase PP2A is essential for optimal B cell function. Jci Insight. 5. PMID 32161189 DOI: 10.1172/Jci.Insight.130655 |
0.407 |
|
| 2020 |
Crispin JC, Tsokos GC. Cancer immunosurveillance by CD8 T cells F1000research. 9: 80. PMID 32089832 DOI: 10.12688/F1000Research.21150.1 |
0.353 |
|
| 2020 |
Rodríguez‐Rodríguez N, Flores‐Mendoza G, Apostolidis SA, Rosetti F, Tsokos GC, Crispín JC. TCR-α/β CD4- CD8- double negative T cells arise from CD8+ T cells. Journal of Leukocyte Biology. 108: 851-857. PMID 32052478 DOI: 10.1002/Jlb.1Ab0120-548R |
0.357 |
|
| 2020 |
Tsokos GC. Notch notches lupus. Kidney International. 97: 251-253. PMID 31980071 DOI: 10.1016/J.Kint.2019.10.018 |
0.302 |
|
| 2020 |
Sharabi A, Tsokos GC. T cell metabolism: new insights in systemic lupus erythematosus pathogenesis and therapy. Nature Reviews Rheumatology. 16: 100-112. PMID 31949287 DOI: 10.1038/S41584-019-0356-X |
0.393 |
|
| 2020 |
Katsuyama E, Suarez-Fueyo A, Bradley SJ, Mizui M, Marin AV, Mulki L, Krishfield S, Malavasi F, Yoon J, Sui SJH, Kyttaris VC, Tsokos GC. The CD38/NAD/SIRTUIN1/EZH2 Axis Mitigates Cytotoxic CD8 T Cell Function and Identifies Patients with SLE Prone to Infections. Cell Reports. 30: 112-123.e4. PMID 31914379 DOI: 10.1016/J.Celrep.2019.12.014 |
0.412 |
|
| 2020 |
Seridi L, Cesaroni M, Loza M, Schreiter J, Sweet K, Campbell K, Lipsky P, Vollenhoven Rv, Hahn BH, Tsokos GC, Chevrier M, Rose S, Baribaud F, Jordan J. O9 Reduction of interferon-γ and elevated baseline cytotoxic gene expression in the blood associate with ustekinumab response in SLE Lupus Science & Medicine. 7. DOI: 10.1136/Lupus-2020-Eurolupus.22 |
0.335 |
|
| 2020 |
Seridi L, Cesaroni M, Loza MJ, Schreiter J, Sweet K, Orlovsky Y, Baribaud I, Orillion A, Lipsky P, Vollenhoven RV, Hahn BH, Tsokos G, Chevrier M, Rose S, Baribaud F, et al. Op0161 Association Of Baseline Cytotoxic Gene Expression With Ustekinumab Response In Systemic Lupus Erythematosus Annals of the Rheumatic Diseases. 79: 101-102. DOI: 10.1136/Annrheumdis-2020-Eular.2407 |
0.315 |
|
| 2019 |
Kono M, Yoshida N, Tsokos GC. Metabolic control of T cells in autoimmunity. Current Opinion in Rheumatology. PMID 31842032 DOI: 10.1097/Bor.0000000000000685 |
0.396 |
|
| 2019 |
Hofmann SR, Mäbert K, Kapplusch F, Russ S, Northey S, Beresford MW, Tsokos GC, Hedrich CM. cAMP Response Element Modulator α Induces Dual Specificity Protein Phosphatase 4 to Promote Effector T Cells in Juvenile-Onset Lupus. Journal of Immunology (Baltimore, Md. : 1950). PMID 31653682 DOI: 10.4049/Jimmunol.1900760 |
0.442 |
|
| 2019 |
Satyam A, Graef ER, Lapchak PH, Tsokos MG, Lucca JJD, Tsokos GC. Complement and coagulation cascades in trauma. Acute Medicine and Surgery. 6: 329-335. PMID 31592318 DOI: 10.1002/Ams2.426 |
0.324 |
|
| 2019 |
Suarez-Fueyo A, Tsokos MG, Kwok SK, Maeda K, Katsuyama E, Lapchak PH, Tsokos GC. Hyaluronic Acid Synthesis Contributes to Tissue Damage in Systemic Lupus Erythematosus. Frontiers in Immunology. 10: 2172. PMID 31572382 DOI: 10.3389/Fimmu.2019.02172 |
0.385 |
|
| 2019 |
Katsuyama T, Li H, Comte D, Tsokos GC, Moulton VR. Splicing factor SRSF1 controls T cell hyperactivity and systemic autoimmunity. The Journal of Clinical Investigation. PMID 31487268 DOI: 10.1172/Jci127949 |
0.457 |
|
| 2019 |
Hedrich CM, Tsokos G. SNPs talk to genes using landlines: long-range chromatin interactions link genetic risk with epigenetic patterns in Takayasu arteritis. Annals of the Rheumatic Diseases. 78: 1293-1295. PMID 31391179 DOI: 10.1136/Annrheumdis-2019-215957 |
0.3 |
|
| 2019 |
Yigit B, Wang N, Ten Hacken E, Chen SS, Bhan AK, Suarez Fueyo A, Katsuyama E, Tsokos GC, Chiorazzi N, Wu CJ, Burger J, Herzog RW, Engel P, Terhorst C. SLAMF6 as a regulator of exhausted CD8+ T cells in cancer. Cancer Immunology Research. PMID 31315913 DOI: 10.1158/2326-6066.Cir-18-0664 |
0.38 |
|
| 2019 |
Kono M, Yoshida N, Maeda K, Suárez-Fueyo A, Kyttaris VC, Tsokos GC. Glutaminase 1 Inhibition Reduces Glycolysis and Ameliorates Lupus-like Disease in MRL/lpr Mice and Experimental Autoimmune Encephalomyelitis. Arthritis & Rheumatology (Hoboken, N.J.). PMID 31233276 DOI: 10.1002/Art.41019 |
0.337 |
|
| 2019 |
Kono M, Maeda K, Stocton-Gavanescu I, Pan W, Umeda M, Katsuyama E, Burbano C, Orite SYK, Vukelic M, Tsokos MG, Yoshida N, Tsokos GC. Pyruvate kinase M2 is requisite for Th1 and Th17 differentiation. Jci Insight. 4. PMID 31217348 DOI: 10.1172/Jci.Insight.127395 |
0.406 |
|
| 2019 |
Ding Y, Yu A, Tsokos GC, Malek TR. CD25 and Protein Phosphatase 2A Cooperate to Enhance IL-2R Signaling in Human Regulatory T Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 31085588 DOI: 10.4049/Jimmunol.1801570 |
0.362 |
|
| 2019 |
Satyam A, Andreo K, Lapchak PH, Dalle Lucca JJ, Davis RB, Tsokos MG, Shapiro NI, Tsokos GC. Complement Deposition on the Surface of RBC After Trauma Serves A Biomarker of Moderate Trauma Severity: A Prospective Study. Shock (Augusta, Ga.). PMID 30998651 DOI: 10.1097/Shk.0000000000001348 |
0.688 |
|
| 2019 |
Sharabi A, Li H, Kasper IR, Pan W, Meidan E, Tsokos MG, Moulton VR, Tsokos GC. PP2A enables IL-2 signaling by preserving IL-2Rβ chain expression during Treg development. Jci Insight. 5. PMID 30912768 DOI: 10.1172/Jci.Insight.126294 |
0.315 |
|
| 2019 |
Koga T, Ichinose K, Kawakami A, Tsokos GC. The role of IL-17 in systemic lupus erythematosus and its potential as a therapeutic target. Expert Review of Clinical Immunology. PMID 30874446 DOI: 10.1080/1744666X.2019.1593141 |
0.348 |
|
| 2019 |
Bhargava R, Tsokos GC. The immune podocyte. Current Opinion in Rheumatology. 31: 167-174. PMID 30562182 DOI: 10.1097/Bor.0000000000000578 |
0.324 |
|
| 2019 |
Comte D, Karampetsou MP, Humbel M, Tsokos GC. Signaling lymphocyte activation molecule family in systemic lupus erythematosus. Clinical Immunology. 204: 57-63. PMID 30415085 DOI: 10.1016/J.Clim.2018.11.001 |
0.372 |
|
| 2019 |
Jordan J, Sweet K, Cesaroni M, Ma K, Franks C, Seridi L, Schreiter J, Gordon R, Lipsky P, Vollenhoven Rv, Tsokos GC, Hahn BH, Rose S, Baribaud F, Loza MJ, et al. 251 Type II but not type I interferon signifies clinical response to ustekinumab in patients with systemic lupus erythematosus Lupus Science & Medicine. 6. DOI: 10.1136/Lupus-2019-Lsm.251 |
0.32 |
|
| 2019 |
Vollenhoven Rv, Hahn BH, Tsokos GC, Rose S. 201 Ustekinumab targets a novel mechanism of action to treat patients with systemic lupus erythematosus Lupus Science & Medicine. 6. DOI: 10.1136/Lupus-2019-Lsm.201 |
0.308 |
|
| 2019 |
Tsokos G. Sp0083 Molecular And Metabolic Events Which Underwrite T Cell Phenotypes In Autoimmunity Annals of the Rheumatic Diseases. DOI: 10.1136/Annrheumdis-2019-Eular.8604 |
0.315 |
|
| 2019 |
Cesaroni M, Seridi L, Jordan J, Sweet K, Keying M, Franks C, Schreiter J, Lipsky P, Vollenhoven Rv, Hahn BH, Rose S, Baribaud F, Loza MJ, Campbell K, Tsokos G. Op0278 Biomarker Profiling Reveals Novel Mechanistic Insights Into Ustekinumab Therapeutic Responses In Systemic Lupus Erythematosus Annals of the Rheumatic Diseases. 78: 220-221. DOI: 10.1136/Annrheumdis-2019-Eular.2452 |
0.319 |
|
| 2018 |
Ferretti AP, Bhargava R, Dahan S, Tsokos MG, Tsokos GC. Calcium/Calmodulin Kinase IV Controls the Function of Both T Cells and Kidney Resident Cells. Frontiers in Immunology. 9: 2113. PMID 30333818 DOI: 10.3389/Fimmu.2018.02113 |
0.418 |
|
| 2018 |
Sharabi A, Tsokos MG, Ding Y, Malek TR, Klatzmann D, Tsokos GC. Regulatory T cells in the treatment of disease. Nature Reviews. Drug Discovery. PMID 30310234 DOI: 10.1038/Nrd.2018.148 |
0.403 |
|
| 2018 |
van Vollenhoven RF, Hahn BH, Tsokos GC, Wagner CL, Lipsky P, Touma Z, Werth VP, Gordon RM, Zhou B, Hsu B, Chevrier M, Triebel M, Jordan JL, Rose S. Efficacy and safety of ustekinumab, an IL-12 and IL-23 inhibitor, in patients with active systemic lupus erythematosus: results of a multicentre, double-blind, phase 2, randomised, controlled study. Lancet (London, England). PMID 30249507 DOI: 10.1016/S0140-6736(18)32167-6 |
0.317 |
|
| 2018 |
Kono M, Yoshida N, Maeda K, Skinner NE, Pan W, Kyttaris VC, Tsokos MG, Tsokos GC. Pyruvate dehydrogenase phosphatase catalytic subunit 2 limits Th17 differentiation. Proceedings of the National Academy of Sciences of the United States of America. PMID 30150402 DOI: 10.1073/Pnas.1805717115 |
0.407 |
|
| 2018 |
Li H, Tsokos MG, Bickerton S, Sharabi A, Li Y, Moulton VR, Kong P, Fahmy TM, Tsokos GC. Precision DNA demethylation ameliorates disease in lupus-prone mice. Jci Insight. 3. PMID 30135300 DOI: 10.1172/Jci.Insight.120880 |
0.383 |
|
| 2018 |
Karampetsou MP, Comte D, Suárez-Fueyo A, Katsuyama E, Yoshida N, Kono M, Kyttaris VC, Tsokos GC. SLAMF1 engagement inhibits T cell-B cell interaction and diminishes IL-6 production and plasmablast differentiation in systemic lupus erythematosus. Arthritis & Rheumatology (Hoboken, N.J.). PMID 30058241 DOI: 10.1002/Art.40682 |
0.393 |
|
| 2018 |
Maeda K, Otomo K, Yoshida N, Abu-Asab MS, Ichinose K, Nishino T, Kono M, Ferretti A, Bhargava R, Maruyama S, Bickerton S, Fahmy TM, Tsokos MG, Tsokos GC. CaMK4 compromises podocyte function in autoimmune and nonautoimmune kidney disease. The Journal of Clinical Investigation. PMID 29985166 DOI: 10.1172/Jci99507 |
0.369 |
|
| 2018 |
Katsuyama E, Yan M, Watanabe KS, Narazaki M, Matsushima S, Yamamura Y, Hiramatsu S, Ohashi K, Watanabe H, Katsuyama T, Zeggar S, Yoshida N, Moulton VR, Tsokos GC, Sada KE, et al. Correction: Downregulation of miR-200a-3p, Targeting CtBP2 Complex, Is Involved in the Hypoproduction of IL-2 in Systemic Lupus Erythematosus-Derived T Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 29941662 DOI: 10.4049/Jimmunol.1800810 |
0.321 |
|
| 2018 |
Kono M, Kurita T, Yasuda S, Kono M, Fujieda Y, Bohgaki T, Katsuyama T, Tsokos GC, Moulton VR, Atsumi T. Decreased expression of Serine/arginine-rich splicing factor 1 in T cells from patients with active systemic lupus erythematosus accounts for reduced expression of RasGRP1 and DNA methyltransferase 1. Arthritis & Rheumatology (Hoboken, N.J.). PMID 29905030 DOI: 10.1002/Art.40585 |
0.418 |
|
| 2018 |
Katsuyama T, Tsokos GC, Moulton VR. Aberrant T Cell Signaling and Subsets in Systemic Lupus Erythematosus. Frontiers in Immunology. 9: 1088. PMID 29868033 DOI: 10.3389/Fimmu.2018.01088 |
0.438 |
|
| 2018 |
Mizui M, Tsokos GC. Targeting Regulatory T Cells to Treat Patients With Systemic Lupus Erythematosus Frontiers in Immunology. 9: 786-786. PMID 29755456 DOI: 10.3389/Fimmu.2018.00786 |
0.41 |
|
| 2018 |
Suárez-Fueyo A, Bradley SJ, Katsuyama T, Solomon S, Katsuyama E, Kyttaris VC, Moulton VR, Tsokos GC. Downregulation of CD3ζ in NK Cells from Systemic Lupus Erythematosus Patients Confers a Proinflammatory Phenotype. Journal of Immunology (Baltimore, Md. : 1950). PMID 29602774 DOI: 10.4049/Jimmunol.1700588 |
0.379 |
|
| 2018 |
Kono M, Yoshida N, Maeda K, Tsokos GC. Transcriptional factor ICER promotes glutaminolysis and the generation of Th17 cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 29463741 DOI: 10.1073/Pnas.1714717115 |
0.409 |
|
| 2018 |
Kwok SK, Tsokos GC. New insights into the role of renal resident cells in the pathogenesis of lupus nephritis. The Korean Journal of Internal Medicine. PMID 29320847 DOI: 10.3904/Kjim.2017.383 |
0.389 |
|
| 2018 |
Psarras A, Alase A, Antanaviciute A, Carr I, Wittmann M, Tsokos G, Emery P, Vital EM. OP0180 Type i interferon is produced by non-haematopoietic tissue resident cells but not pdcs in pre-clinical autoimmunity and sle Annals of the Rheumatic Diseases. 77: 139-140. DOI: 10.1136/Annrheumdis-2018-Eular.5407 |
0.376 |
|
| 2018 |
Psarras A, Antanaviciute A, Carr I, Wittmann M, Emery P, Tsokos G, Vital EM. SAT0019 Tnf-Α regulates plasmacytoid dendritic cells by suppressing ifn-Α production and enhancing th1 and th17 cell differentiation Annals of the Rheumatic Diseases. 77: 877-877. DOI: 10.1136/Annrheumdis-2018-Eular.4688 |
0.303 |
|
| 2017 |
Crispin JC, Hedrich CM, Suárez-Fueyo A, Comte D, Tsokos GC. SLE-Associated Defects Promote Altered T Cell Function. Critical Reviews in Immunology. 37: 39-58. PMID 29431078 DOI: 10.1615/Critrevimmunol.2018025213 |
0.424 |
|
| 2017 |
Lo MS, Tsokos GC. Recent developments in systemic lupus erythematosus pathogenesis and applications for therapy. Current Opinion in Rheumatology. PMID 29206660 DOI: 10.1097/Bor.0000000000000474 |
0.338 |
|
| 2017 |
Karampetsou MP, Comte D, Kis-Toth K, Kyttaris VC, Tsokos GC. Expression patterns of signaling lymphocytic activation molecule family members in peripheral blood mononuclear cell subsets in patients with systemic lupus erythematosus. Plos One. 12. PMID 29020082 DOI: 10.1371/Journal.Pone.0186073 |
0.442 |
|
| 2017 |
Matsumoto N, Satyam A, Geha M, Lapchak PH, Lucca JJD, Tsokos MG, Tsokos GC. C3a Enhances the Formation of Intestinal Organoids through C3aR1. Frontiers in Immunology. 8: 1046. PMID 28928734 DOI: 10.3389/Fimmu.2017.01046 |
0.702 |
|
| 2017 |
Nishi H, Furuhashi K, Cullere X, Saggu G, Miller MJ, Chen Y, Rosetti F, Hamilton SL, Yang L, Pittman SP, Liao J, Herter JM, Berry JC, DeAngelo DJ, Zhu C, ... Tsokos GC, et al. Neutrophil FcγRIIA promotes IgG-mediated glomerular neutrophil capture via Abl/Src kinases. The Journal of Clinical Investigation. PMID 28891817 DOI: 10.1172/Jci94039 |
0.32 |
|
| 2017 |
Geha M, Tsokos MG, Bosse RE, Sannikova T, Iwakura Y, Lucca JJD, Malefyt RDW, Tsokos GC. IL-17A Produced by Innate Lymphoid Cells Is Essential for Intestinal Ischemia-Reperfusion Injury. Journal of Immunology. 199: 2921-2929. PMID 28877988 DOI: 10.4049/Jimmunol.1700655 |
0.316 |
|
| 2017 |
Tsokos GC. Fat T cells go to the joint Nature Immunology. 18: 955-956. PMID 28829450 DOI: 10.1038/Ni.3810 |
0.337 |
|
| 2017 |
Sharabi A, Kasper IR, Tsokos GC. The serine/threonine protein phosphatase 2A controls autoimmunity. Clinical Immunology. 186: 38-42. PMID 28736280 DOI: 10.1016/J.Clim.2017.07.012 |
0.435 |
|
| 2017 |
Dai H, He F, Tsokos GC, Kyttaris VC. IL-23 Limits the Production of IL-2 and Promotes Autoimmunity in Lupus. Journal of Immunology (Baltimore, Md. : 1950). PMID 28646040 DOI: 10.4049/Jimmunol.1700418 |
0.338 |
|
| 2017 |
Moulton VR, Suarez-Fueyo A, Meidan E, Li H, Mizui M, Tsokos GC. Pathogenesis of Human Systemic Lupus Erythematosus: A Cellular Perspective. Trends in Molecular Medicine. PMID 28623084 DOI: 10.1016/J.Molmed.2017.05.006 |
0.385 |
|
| 2017 |
Bialas AR, Presumey J, Das A, van der Poel CE, Lapchak PH, Mesin L, Victora G, Tsokos GC, Mawrin C, Herbst R, Carroll MC. Microglia-dependent synapse loss in type I interferon-mediated lupus. Nature. PMID 28614301 DOI: 10.1038/Nature22821 |
0.334 |
|
| 2017 |
Tsokos GC, Rose NR. Immune cell signaling in autoimmune diseases. Clinical Immunology (Orlando, Fla.). 181: 1-8. PMID 28531376 DOI: 10.1016/J.Clim.2017.05.015 |
0.404 |
|
| 2017 |
Katsuyama E, Yan M, Watanabe KS, Matsushima S, Yamamura Y, Hiramatsu S, Ohashi K, Watanabe H, Katsuyama T, Zeggar S, Yoshida N, Moulton VR, Tsokos GC, Sada KE, Wada J. Downregulation of miR-200a-3p, Targeting CtBP2, Is Involved in the Hypoproduction of IL-2 in Systemic Lupus Erythematosus-Derived T Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 28438897 DOI: 10.4049/Jimmunol.1601705 |
0.335 |
|
| 2017 |
Suárez-Fueyo A, Bradley SJ, Klatzmann D, Tsokos GC. T cells and autoimmune kidney disease. Nature Reviews. Nephrology. PMID 28287110 DOI: 10.1038/Nrneph.2017.34 |
0.422 |
|
| 2017 |
Zhou Y, Chen H, Liu L, Yu X, Sukhova GK, Yang M, Zhang L, Kyttaris VC, Tsokos GC, Stillman IE, Ichimura T, Bonventre JV, Libby P, Shi GP. CD74 Deficiency Mitigates Systemic Lupus Erythematosus-like Autoimmunity and Pathological Findings in Mice. Journal of Immunology (Baltimore, Md. : 1950). PMID 28219888 DOI: 10.4049/Jimmunol.1600028 |
0.375 |
|
| 2017 |
Zhou Y, Chen H, Liu L, Yu X, Sukhova GK, Yang M, Kyttaris VC, Stillman IE, Gelb B, Libby P, Tsokos GC, Shi GP. Cathepsin K Deficiency Ameliorates Systemic Lupus Erythematosus-like Manifestations in Faslpr Mice. Journal of Immunology (Baltimore, Md. : 1950). PMID 28093526 DOI: 10.4049/Jimmunol.1501145 |
0.36 |
|
| 2017 |
Comte D, Karampetsou MP, Yoshida N, Kis‐Toth K, Kyttaris VC, Tsokos GC. Signaling Lymphocytic Activation Molecule Family Member 7 Engagement Restores Defective Effector CD8+ T Cell Function in Systemic Lupus Erythematosus. Arthritis & Rheumatism. 69: 1035-1044. PMID 28076903 DOI: 10.1002/Art.40038 |
0.425 |
|
| 2017 |
Hedrich CM, Mäbert K, Rauen T, Tsokos GC. DNA methylation in systemic lupus erythematosus. Epigenomics. 9: 505-525. PMID 27885845 DOI: 10.2217/Epi-2016-0096 |
0.374 |
|
| 2016 |
Comte D, Karampetsou MP, Kis-Toth K, Yoshida N, Bradley SJ, Kyttaris VC, Tsokos GC. CD4+ T cells from SLE patients respond poorly to exogenous IL-2. Arthritis & Rheumatology (Hoboken, N.J.). PMID 27992687 DOI: 10.1002/Art.40014 |
0.373 |
|
| 2016 |
Satyam A, Kannan L, Matsumoto N, Geha M, Lapchak PH, Bosse R, Shi GP, Dalle Lucca JJ, Tsokos MG, Tsokos GC. Intracellular Activation of Complement 3 Is Responsible for Intestinal Tissue Damage during Mesenteric Ischemia. Journal of Immunology (Baltimore, Md. : 1950). PMID 27913632 DOI: 10.4049/Jimmunol.1502287 |
0.705 |
|
| 2016 |
Tsokos GC, Lo MS, Reis PC, Sullivan KE. New insights into the immunopathogenesis of systemic lupus erythematosus. Nature Reviews. Rheumatology. 12: 716-730. PMID 27872476 DOI: 10.1038/Nrrheum.2016.186 |
0.378 |
|
| 2016 |
Massaad MJ, Zhou J, Tsuchimoto D, Chou J, Jabara H, Janssen E, Glauzy S, Olson BG, Morbach H, Ohsumi TK, Schmitz K, Kyriacos M, Kane J, Torisu K, Nakabeppu Y, ... ... Tsokos GC, et al. Deficiency of base excision repair enzyme NEIL3 drives increased predisposition to autoimmunity. The Journal of Clinical Investigation. PMID 27760045 DOI: 10.1172/Jci85647 |
0.379 |
|
| 2016 |
Mizui M, Tsokos GC. Low-Dose IL-2 in the Treatment of Lupus. Current Rheumatology Reports. 18: 68-68. PMID 27734211 DOI: 10.1007/S11926-016-0617-5 |
0.351 |
|
| 2016 |
Yoshida N, Comte D, Mizui M, Otomo K, Rosetti F, Mayadas TN, Crispín JC, Bradley SJ, Koga T, Kono M, Karampetsou MP, Kyttaris VC, Tenbrock K, Tsokos GC. ICER is requisite for Th17 differentiation. Nature Communications. 7: 12993. PMID 27680869 DOI: 10.1038/Ncomms12993 |
0.442 |
|
| 2016 |
Suárez-Fueyo A, Bradley SJ, Tsokos GC. T cells in Systemic Lupus Erythematosus. Current Opinion in Immunology. 43: 32-38. PMID 27636649 DOI: 10.1016/J.Coi.2016.09.001 |
0.431 |
|
| 2016 |
Exley MA, Tsokos GC, Mills KH, Elewaut D, Mulhearn B. What rheumatologists need to know about innate lymphocytes. Nature Reviews. Rheumatology. 12: 658-668. PMID 27586381 DOI: 10.1038/Nrrheum.2016.140 |
0.379 |
|
| 2016 |
Comte D, Karampetsou MP, Kis-Toth K, Yoshida N, Bradley SJ, Mizui M, Kono M, Solomon JR, Kyttaris VC, Tsokos GC. Engagement of SLAMF3 enhances CD4+ T-cell sensitivity to IL-2 and favors regulatory T-cell polarization in systemic lupus erythematosus. Proceedings of the National Academy of Sciences of the United States of America. PMID 27482100 DOI: 10.1073/Pnas.1605081113 |
0.418 |
|
| 2016 |
Kasper IR, Apostolidis SA, Sharabi A, Tsokos GC. Empowering Regulatory T Cells in Autoimmunity Trends in Molecular Medicine. 22: 784-797. PMID 27461103 DOI: 10.1016/J.Molmed.2016.07.003 |
0.399 |
|
| 2016 |
Karampetsou MP, Comte D, Kis-Toth K, Terhorst C, Kyttaris VC, Tsokos GC. Decreased SAP Expression in T Cells from Patients with Systemic Lupus Erythematosus Contributes to Early Signaling Abnormalities and Reduced IL-2 Production. Journal of Immunology (Baltimore, Md. : 1950). 196: 4915-24. PMID 27183584 DOI: 10.4049/Jimmunol.1501523 |
0.459 |
|
| 2016 |
Wang J, Mizui M, Zeng LF, Bronson R, Finnell M, Terhorst C, Kyttaris VC, Tsokos GC, Zhang ZY, Kontaridis MI. Inhibition of SHP2 ameliorates the pathogenesis of systemic lupus erythematosus. The Journal of Clinical Investigation. PMID 27183387 DOI: 10.1172/Jci87037 |
0.428 |
|
| 2016 |
Wei S, Yoshida N, Finn G, Kozono S, Nechama M, Kyttaris VC, Zhou XZ, Tsokos GC, Lu KP. Pin1-targeted therapy against systemic lupus erythematosus. Arthritis & Rheumatology (Hoboken, N.J.). PMID 27159270 DOI: 10.1002/Art.39741 |
0.353 |
|
| 2016 |
Koga T, Ichinose K, Tsokos GC. T cells and IL-17 in lupus nephritis. Clinical Immunology (Orlando, Fla.). PMID 27109641 DOI: 10.1016/J.Clim.2016.04.010 |
0.43 |
|
| 2016 |
Munroe ME, Lu R, Zhao YD, Fife DA, Robertson JM, Guthridge JM, Niewold TB, Tsokos GC, Keith MP, Harley JB, James JA. Altered type II interferon precedes autoantibody accrual and elevated type I interferon activity prior to systemic lupus erythematosus classification. Annals of the Rheumatic Diseases. PMID 27088255 DOI: 10.1136/Annrheumdis-2015-208140 |
0.335 |
|
| 2016 |
Rodríguez-Rodríguez N, Apostolidis SA, Fitzgerald L, Meehan BS, Corbett AJ, Martín-Villa JM, McCluskey J, Tsokos GC, Crispín JC. Pro-inflammatory self-reactive T cells are found within murine TCR-αβ(+) CD4(-) CD8(-) PD-1(+) cells. European Journal of Immunology. PMID 27060346 DOI: 10.1002/Eji.201546056 |
0.376 |
|
| 2016 |
Tsokos GC. Metabolic control of arthritis: Switch pathways to treat. Science Translational Medicine. 8. PMID 27009266 DOI: 10.1126/Scitranslmed.Aaf4953 |
0.318 |
|
| 2016 |
Deng GM, Tsokos GC. The role of Syk in cutaneous lupus erythematosus Experimental Dermatology. 25: 674-675. PMID 26999068 DOI: 10.1111/Exd.13018 |
0.306 |
|
| 2016 |
Apostolidis SA, Rodríguez-Rodríguez N, Suárez-Fueyo A, Dioufa N, Ozcan E, Crispín JC, Tsokos MG, Tsokos GC. Phosphatase PP2A is requisite for the function of regulatory T cells. Nature Immunology. 17: 556-64. PMID 26974206 DOI: 10.1038/Ni.3390 |
0.402 |
|
| 2016 |
Koga T, Otomo K, Mizui M, Yoshida N, Umeda M, Ichinose K, Kawakami A, Tsokos GC. CaMK4 facilitates the recruitment of IL-17-producing cells to target organs through the CCR6/CCL20 axis in Th17-driven inflammatory diseases. Arthritis & Rheumatology (Hoboken, N.J.). PMID 26945541 DOI: 10.1002/Art.39665 |
0.4 |
|
| 2016 |
Tsokos GC. Systemic lupus erythematosus in 2015: Cellular and metabolic requirements of effector T cells. Nature Reviews Rheumatology. 12: 74-76. PMID 26729463 DOI: 10.1038/Nrrheum.2015.178 |
0.413 |
|
| 2016 |
Kis-Toth K, Comte D, Karampetsou MP, Kyttaris VC, Kannan L, Terhorst C, Tsokos GC. Selective Loss of Signaling Lymphocytic Activation Molecule Family Member 4-Positive CD8+ T Cells Contributes to the Decreased Cytotoxic Cell Activity in Systemic Lupus Erythematosus. Arthritis & Rheumatology (Hoboken, N.J.). 68: 164-73. PMID 26314831 DOI: 10.1002/Art.39410 |
0.396 |
|
| 2016 |
Deng GM, Kyttaris VC, Tsokos GC. Targeting syk in autoimmune rheumatic diseases Frontiers in Immunology. 7. DOI: 10.3389/Fimmu.2016.00078 |
0.379 |
|
| 2016 |
Munroe ME, Lu R, Slight-Webb SR, Guthridge JM, Niewold TB, Tsokos GC, Keith MP, Harley JB, James JA. I-03 Dysregulation of T helper-type cytokines and interferons appear during early systemic lupus erythematosus pathogenesis and contribute to clinical disease development Lupus Science & Medicine. 3. DOI: 10.1136/Lupus-2016-000179.68 |
0.364 |
|
| 2016 |
Tsokos GC. AI-24 Calcium/calmodulin kinase controls T and renal cell function Lupus Science & Medicine. 3. DOI: 10.1136/Lupus-2016-000179.24 |
0.442 |
|
| 2015 |
Ichinose K, Ushigusa T, Nishino A, Nakashima Y, Suzuki T, Horai Y, Koga T, Kawashiri SY, Iwamoto N, Tamai M, Arima K, Nakamura H, Obata Y, Yamamoto K, Origuchi T, ... ... Tsokos GC, et al. Lupus nephritis IgG induces the expression of calcium/calmodulin-dependent kinase type IV in podocytes and alters their function. Arthritis & Rheumatology (Hoboken, N.J.). PMID 26636664 DOI: 10.1002/Art.39499 |
0.412 |
|
| 2015 |
Otomo K, Koga T, Mizui M, Yoshida N, Kriegel C, Bickerton S, Fahmy TM, Tsokos GC. Cutting Edge: Nanogel-Based Delivery of an Inhibitor of CaMK4 to CD4+ T Cells Suppresses Experimental Autoimmune Encephalomyelitis and Lupus-like Disease in Mice. Journal of Immunology (Baltimore, Md. : 1950). 195: 5533-7. PMID 26561550 DOI: 10.4049/Jimmunol.1501603 |
0.424 |
|
| 2015 |
Bradley SJ, Suarez-Fueyo A, Moss DR, Kyttaris VC, Tsokos GC. T Cell Transcriptomes Describe Patient Subtypes in Systemic Lupus Erythematosus. Plos One. 10: e0141171. PMID 26544975 DOI: 10.1371/Journal.Pone.0141171 |
0.423 |
|
| 2015 |
Volpi S, Santori E, Abernethy K, Mizui M, Dahlberg CI, Recher M, Capuder K, Csizmadia E, Ryan D, Mathew D, Tsokos GC, Snapper S, Westerberg LS, Thrasher AJ, Candotti F, et al. N-WASP is required for B cell-mediated autoimmunity in the Wiskott-Aldrich syndrome. Blood. PMID 26468226 DOI: 10.1182/Blood-2015-05-643817 |
0.345 |
|
| 2015 |
Deng G, Tsokos GC. Pathogenesis and targeted treatment of skin injury in SLE Nature Reviews Rheumatology. 11: 663-669. PMID 26241186 DOI: 10.1038/Nrrheum.2015.106 |
0.325 |
|
| 2015 |
Konya C, Paz Z, Apostolidis SA, Tsokos GC. Update on the role of Interleukin 17 in rheumatologic autoimmune diseases. Cytokine. 75: 207-215. PMID 26028353 DOI: 10.1016/J.Cyto.2015.01.003 |
0.407 |
|
| 2015 |
Lieberman LA, Mizui M, Nalbandian A, Bossé R, Crispín JC, Tsokos GC. Complement receptor of the immunoglobulin superfamily reduces murine lupus nephritis and cutaneous disease. Clinical Immunology. 160: 286-291. PMID 25988858 DOI: 10.1016/J.Clim.2015.05.006 |
0.37 |
|
| 2015 |
Moulton VR, Tsokos GC. T cell signaling abnormalities contribute to aberrant immune cell function and autoimmunity Journal of Clinical Investigation. 125: 2220-2227. PMID 25961450 DOI: 10.1172/Jci78087 |
0.433 |
|
| 2015 |
Rodríguez-Rodríguez N, Apostolidis SA, Penaloza-MacMaster P, Villa JMM, Barouch DH, Tsokos GC, Crispín JC. Programmed Cell Death 1 and Helios Distinguish TCR-αβ+ Double-Negative (CD4−CD8−) T Cells That Derive from Self-Reactive CD8 T Cells Journal of Immunology. 194: 4207-4214. PMID 25825451 DOI: 10.4049/Jimmunol.1402775 |
0.378 |
|
| 2015 |
Tsokos GC. Target It All Right, But Do Not Forget the Torchbearer Circulation. 131: 1153-1155. PMID 25825395 DOI: 10.1161/Circulationaha.115.015613 |
0.335 |
|
| 2015 |
Comte D, Karampetsou MP, Tsokos GC. T cells as a therapeutic target in SLE Lupus. 24: 351-363. PMID 25801878 DOI: 10.1177/0961203314556139 |
0.445 |
|
| 2015 |
Walter JE, Lo MS, Kis-Toth K, Tirosh I, Frugoni F, Lee YN, Csomos K, Chen K, Pillai S, Dunham J, Tsokos GC, Luning Prak ET, Notarangelo LD. Impaired receptor editing and heterozygous RAG2 mutation in a patient with systemic lupus erythematosus and erosive arthritis. The Journal of Allergy and Clinical Immunology. 135: 272-3. PMID 25312763 DOI: 10.1016/J.Jaci.2014.07.063 |
0.43 |
|
| 2015 |
Koga T, Otomo K, Mizui M, Yoshida N, Crispin JC, Kawakami A, Tsokos GC. FRI0018 CAMK4 Inhibition Prevents Recruitment of IL-17 Producing Cells to Target Organs Through CCR6/CCL20 Axis in TH17 Driven Inflammatory Diseases Annals of the Rheumatic Diseases. 74: 425-425. DOI: 10.1136/Annrheumdis-2015-Eular.1415 |
0.427 |
|
| 2014 |
Lieberman LA, Tsokos GC. Lupus-Prone Mice Fail to Raise Antigen-Specific T Cell Responses to Intracellular Infection Plos One. 9. PMID 25360768 DOI: 10.1371/Journal.Pone.0111382 |
0.37 |
|
| 2014 |
Hedrich CM, Rauen T, Apostolidis SA, Grammatikos AP, Rodriguez NR, Ioannidis C, Kyttaris VC, Crispin JC, Tsokos GC. Stat3 promotes IL-10 expression in lupus T cells through trans-activation and chromatin remodeling Proceedings of the National Academy of Sciences of the United States of America. 111: 13457-13462. PMID 25187566 DOI: 10.1073/Pnas.1408023111 |
0.387 |
|
| 2014 |
Mizui M, Koga T, Lieberman LA, Beltran J, Yoshida N, Johnson MC, Tisch R, Tsokos GC. IL-2 protects lupus-prone mice from multiple end-organ damage by limiting CD4-CD8- IL-17-producing T cells. Journal of Immunology (Baltimore, Md. : 1950). 193: 2168-77. PMID 25063876 DOI: 10.4049/Jimmunol.1400977 |
0.383 |
|
| 2014 |
Konya C, Paz Z, Tsokos GC. The role of T cells in systemic lupus erythematosus: an update. Current Opinion in Rheumatology. 26: 493-501. PMID 25050923 DOI: 10.1097/Bor.0000000000000082 |
0.405 |
|
| 2014 |
Koga T, Mizui M, Yoshida N, Otomo K, Lieberman LA, Crispín JC, Tsokos GC. KN-93, an inhibitor of calcium/calmodulin-dependent protein kinase IV, promotes generation and function of Foxp3⁺ regulatory T cells in MRL/lpr mice. Autoimmunity. 47: 445-450. PMID 24829059 DOI: 10.3109/08916934.2014.915954 |
0.427 |
|
| 2014 |
Hedrich CM, Crispin JC, Tsokos GC. Epigenetic regulation of cytokine expression in systemic lupus erythematosus with special focus on T cells Autoimmunity. 47: 234-241. PMID 24762298 DOI: 10.3109/08916934.2013.801462 |
0.342 |
|
| 2014 |
Nagpal K, Watanabe KS, Tsao BP, Tsokos GC. Transcription factor Ikaros Represses Protein Phosphatase 2A (PP2A) Expression through an Intronic Binding Site Journal of Biological Chemistry. 289: 13751-13757. PMID 24692537 DOI: 10.1074/Jbc.M114.558197 |
0.337 |
|
| 2014 |
Kis-Toth K, Tsokos GC. Engagement of SLAMF2/CD48 Prolongs the Time Frame of Effective T Cell Activation by Supporting Mature Dendritic Cell Survival Journal of Immunology. 192: 4436-4442. PMID 24670806 DOI: 10.4049/Jimmunol.1302909 |
0.394 |
|
| 2014 |
Koga T, Hedrich CM, Mizui M, Yoshida N, Otomo K, Lieberman LA, Rauen T, Crispín JC, Tsokos GC. CaMK4-dependent activation of AKT/mTOR and CREM-α underlies autoimmunity-associated Th17 imbalance Journal of Clinical Investigation. 124: 2234-2245. PMID 24667640 DOI: 10.1172/Jci73411 |
0.402 |
|
| 2014 |
Grammatikos AP, Kyttaris VC, Kis-Toth K, Fitzgerald LM, Devlin A, Finnell MD, Tsokos GC. A T cell gene expression panel for the diagnosis and monitoring of disease activity in patients with systemic lupus erythematosus. Clinical Immunology (Orlando, Fla.). 150: 192-200. PMID 24434273 DOI: 10.1016/J.Clim.2013.12.002 |
0.412 |
|
| 2014 |
Moulton VR, Gillooly AR, Tsokos GC. Ubiquitination Regulates Expression of the Serine/Arginine-rich Splicing Factor 1 (SRSF1) in Normal and Systemic Lupus Erythematosus (SLE) T Cells Journal of Biological Chemistry. 289: 4126-4134. PMID 24368769 DOI: 10.1074/Jbc.M113.518662 |
0.449 |
|
| 2014 |
Hedrich CM, Crispín JC, Rauen T, Ioannidis C, Koga T, Rodriguez NR, Apostolidis SA, Kyttaris VC, Tsokos GC. cAMP responsive element modulator (CREM) α mediates chromatin remodeling of CD8 during the generation of CD3+ CD4- CD8- T cells. Journal of Biological Chemistry. 289: 2361-2370. PMID 24297179 DOI: 10.1074/Jbc.M113.523605 |
0.415 |
|
| 2014 |
Tsokos GC. A serine/threonine phosphatase, PP2A, controls autoimmunity Arthritis Research & Therapy. 16: 1-23. DOI: 10.1186/Ar4646 |
0.445 |
|
| 2014 |
Hedrich CM, Rauen T, Crispin J, Tsokos G. Stat3 and Stat5 govern IL-10 expression in T cells through trans-activation and epigenetic remodelling in health and disease Molecular and Cellular Pediatrics. 1: 1-1. DOI: 10.1186/2194-7791-1-S1-A17 |
0.375 |
|
| 2014 |
Munroe M, Fife D, Robertson J, Zhao Y, Bruner B, Niewold T, Tsokos G, Keith M, Harley J, James J. OP0097 Autoantibodies Precede Interferon Elevation in Pre-Clinical Lupus Annals of the Rheumatic Diseases. 73: 98.1-98. DOI: 10.1136/Annrheumdis-2014-Eular.3402 |
0.32 |
|
| 2014 |
Koga T, Mizui M, Yoshida N, Otomo K, Lieberman LA, Crispín JC, Kawakami A, Tsokos GC. THU0057 Kn-93, an Inhibitor of Calcium/Calmodulin-Dependent Protein Kinase Iv, Promotes Generation and Function of Foxp3+ Regulatory T Cells in Mrl/Lpr Mice Annals of the Rheumatic Diseases. 73: 195-196. DOI: 10.1136/Annrheumdis-2014-Eular.2491 |
0.474 |
|
| 2014 |
Ichinose K, Ushigusa T, Koga T, Tsokos GC, Kawakami A. THU0048 Role of Calcium/Calmodulin-Dependent Kinase Type IV in Podocyte Function in Lupus Nephritis Annals of the Rheumatic Diseases. 73: 193-193. DOI: 10.1136/Annrheumdis-2014-Eular.1859 |
0.419 |
|
| 2014 |
Davis TE, Kis‐Toth K, Tsokos GC. A114: Methylprednisolone-Induced Inhibition of miR-155 Expression Increases SOCS1-Driven Suppression of Cytokine Signaling Arthritis & Rheumatism. 66. DOI: 10.1002/Art.38535 |
0.328 |
|
| 2013 |
Hedrich CM, Rauen T, Crispin JC, Koga T, Ioannidis C, Zajdel M, Kyttaris VC, Tsokos GC. cAMP-responsive Element Modulator α (CREMα) trans-Represses the Transmembrane Glycoprotein CD8 and Contributes to the Generation of CD3+CD4−CD8− T Cells in Health and Disease Journal of Biological Chemistry. 288: 31880-31887. PMID 24047902 DOI: 10.1074/Jbc.M113.508655 |
0.43 |
|
| 2013 |
Grammatikos AP, Ghosh D, Devlin A, Kyttaris VC, Tsokos GC. Spleen Tyrosine Kinase (Syk) Regulates Systemic Lupus Erythematosus (SLE) T Cell Signaling Plos One. 8. PMID 24013589 DOI: 10.1371/Journal.Pone.0074550 |
0.454 |
|
| 2013 |
Deng GM, Beltran J, Chen C, Terhorst C, Tsokos GC. T cell CD3ζ deficiency enables multiorgan tissue inflammation. Journal of Immunology (Baltimore, Md. : 1950). 191: 3563-7. PMID 23980209 DOI: 10.4049/Jimmunol.1300634 |
0.422 |
|
| 2013 |
Apostolidis SA, Rauen T, Hedrich CM, Tsokos GC, Crispín JC. Protein Phosphatase 2A Enables Expression of Interleukin 17 (IL-17) through Chromatin Remodeling Journal of Biological Chemistry. 288: 26775-26784. PMID 23918926 DOI: 10.1074/Jbc.M113.483743 |
0.416 |
|
| 2013 |
Kyttaris VC, Kampagianni O, Tsokos GC. Treatment with Anti-Interleukin 23 Antibody Ameliorates Disease in Lupus-Prone Mice Biomed Research International. 2013: 861028-861028. PMID 23841097 DOI: 10.1155/2013/861028 |
0.346 |
|
| 2013 |
Sunahori K, Nagpal K, Hedrich CM, Mizui M, Fitzgerald LM, Tsokos GC. The catalytic subunit of protein phosphatase 2A (PP2Ac) promotes DNA hypomethylation by suppressing the phosphorylated mitogen-activated protein kinase/extracellular signal-regulated kinase (ERK) kinase (MEK)/phosphorylated ERK/DNMT1 protein pathway in T-cells from controls and systemic lupus erythematosus patients. The Journal of Biological Chemistry. 288: 21936-44. PMID 23775084 DOI: 10.1074/Jbc.M113.467266 |
0.378 |
|
| 2013 |
Crispín JC, Hedrich CM, Tsokos GC. Gene-function studies in systemic lupus erythematosus Nature Reviews Rheumatology. 9: 476-484. PMID 23732569 DOI: 10.1038/Nrrheum.2013.78 |
0.314 |
|
| 2013 |
Keszei M, Detre C, Castro W, Magelky E, O'Keeffe M, Kis-Toth K, Tsokos GC, Wang N, Terhorst C. Expansion of an osteopontin-expressing T follicular helper cell subset correlates with autoimmunity in B6.Sle1b mice and is suppressed by the H1-isoform of the Slamf6 receptor Faseb Journal. 27: 3123-3131. PMID 23629864 DOI: 10.1096/Fj.12-226951 |
0.395 |
|
| 2013 |
Paz Z, Tsokos GC. New therapeutics in systemic lupus erythematosus. Current Opinion in Rheumatology. 25: 297-303. PMID 23492737 DOI: 10.1097/Bor.0B013E32835Fd682 |
0.344 |
|
| 2013 |
Rauen T, Hedrich CM, Tenbrock K, Tsokos GC. cAMP responsive element modulator: a critical regulator of cytokine production Trends in Molecular Medicine. 19: 262-269. PMID 23491535 DOI: 10.1016/J.Molmed.2013.02.001 |
0.389 |
|
| 2013 |
Moulton VR, Grammatikos AP, Fitzgerald LM, Tsokos GC. Splicing factor SF2/ASF rescues IL-2 production in T cells from systemic lupus erythematosus patients by activating IL-2 transcription. Proceedings of the National Academy of Sciences of the United States of America. 110: 1845-50. PMID 23319613 DOI: 10.1073/Pnas.1214207110 |
0.415 |
|
| 2013 |
Ichinose K, Zhang Z, Koga T, Juang YT, Kis-Tóth K, Sharpe AH, Kuchroo V, Crispín JC, Tsokos GC. Brief report: increased expression of a short splice variant of CTLA-4 exacerbates lupus in MRL/lpr mice. Arthritis and Rheumatism. 65: 764-9. PMID 23203389 DOI: 10.1002/Art.37790 |
0.397 |
|
| 2013 |
Ioannou A, Lieberman LA, Lucca JJD, Tsokos GC. Complement depletion protects lupus-prone mice from ischemia-reperfusion-initiated organ injury American Journal of Physiology-Gastrointestinal and Liver Physiology. 304. PMID 23104558 DOI: 10.1152/Ajpgi.00371.2012 |
0.313 |
|
| 2013 |
Rauen T, Grammatikos A, Hedrich CM, Kyttaris VC, Tenbrock K, Raffetseder U, Floege J, Tsokos GC. THU0004 Camp responsive element modulator (CREM) alpha contributes to decreased NOTCH-1 expression in T cells from patients with systemic lupus erythematosus (SLE) Annals of the Rheumatic Diseases. 71: 155-155. DOI: 10.1136/Annrheumdis-2012-Eular.1969 |
0.455 |
|
| 2012 |
del Rio R, McAllister RD, Meeker ND, Wall EH, Bond JP, Kyttaris VC, Tsokos GC, Tung KS, Teuscher C. Identification of Orch3, a locus controlling dominant resistance to autoimmune orchitis, as kinesin family member 1C. Plos Genetics. 8: e1003140. PMID 23300462 DOI: 10.1371/Journal.Pgen.1003140 |
0.312 |
|
| 2012 |
Rauen T, Grammatikos AP, Hedrich CM, Floege J, Tenbrock K, Ohl K, Kyttaris VC, Tsokos GC. cAMP-responsive Element Modulator α (CREMα) Contributes to Decreased Notch-1 Expression in T Cells from Patients with Active Systemic Lupus Erythematosus (SLE) Journal of Biological Chemistry. 287: 42525-42532. PMID 23124208 DOI: 10.1074/Jbc.M112.425371 |
0.408 |
|
| 2012 |
Hedrich CM, Crispin JC, Rauen T, Ioannidis C, Apostolidis SA, Lo MS, Kyttaris VC, Tsokos GC. cAMP response element modulator α controls IL2 and IL17A expression during CD4 lineage commitment and subset distribution in lupus. Proceedings of the National Academy of Sciences of the United States of America. 109: 16606-11. PMID 23019580 DOI: 10.1073/Pnas.1210129109 |
0.378 |
|
| 2012 |
Chatterjee M, Hedrich CM, Rauen T, Ioannidis C, Terhorst C, Tsokos GC. CD3-T cell receptor co-stimulation through SLAMF3 and SLAMF6 receptors enhances RORγt recruitment to the IL17A promoter in human T lymphocytes. The Journal of Biological Chemistry. 287: 38168-77. PMID 22989874 DOI: 10.1074/Jbc.M112.415067 |
0.44 |
|
| 2012 |
Koga T, Ichinose K, Mizui M, Crispín JC, Tsokos GC. Calcium/Calmodulin-Dependent Protein Kinase IV Suppresses IL-2 Production and Regulatory T Cell Activity in Lupus Journal of Immunology. 189: 3490-3496. PMID 22942433 DOI: 10.4049/Jimmunol.1201785 |
0.435 |
|
| 2012 |
Rosetti F, Tsuboi N, Chen K, Nishi H, Ernandez T, Sethi S, Croce K, Stavrakis G, Alcocer-Varela J, Gómez-Martin D, van Rooijen N, Kyttaris VC, Lichtman AH, Tsokos GC, Mayadas TN. Human lupus serum induces neutrophil-mediated organ damage in mice that is enabled by Mac-1 deficiency. Journal of Immunology (Baltimore, Md. : 1950). 189: 3714-23. PMID 22933624 DOI: 10.4049/Jimmunol.1201594 |
0.365 |
|
| 2012 |
Moulton VR, Lo MS, Tsokos GC. Methods and protocols to study T cell signaling abnormalities in human systemic lupus erythematosus. Methods in Molecular Biology (Clifton, N.J.). 900: 25-60. PMID 22933064 DOI: 10.1007/978-1-60761-720-4_3 |
0.441 |
|
| 2012 |
Lapchak PH, Ioannou A, Rani P, Lieberman LA, Yoshiya K, Kannan L, Dalle Lucca JJ, Kowalska MA, Tsokos GC. The role of platelet factor 4 in local and remote tissue damage in a mouse model of mesenteric ischemia/reperfusion injury. Plos One. 7: e39934. PMID 22792197 DOI: 10.1371/Journal.Pone.0039934 |
0.31 |
|
| 2012 |
Tsokos GC, Thai TH. Interleukin-2 in systemic autoimmunity hits the micro way. Arthritis and Rheumatism. 64: 3494-7. PMID 22736339 DOI: 10.1002/Art.34597 |
0.315 |
|
| 2012 |
Detre C, Keszei M, Garrido-Mesa N, Kis-Toth K, Castro W, Agyemang AF, Veerapen N, Besra GS, Carroll MC, Tsokos GC, Wang N, Leadbetter EA, Terhorst C. SAP expression in invariant NKT cells is required for cognate help to support B-cell responses. Blood. 120: 122-9. PMID 22613797 DOI: 10.1182/Blood-2011-11-395913 |
0.418 |
|
| 2012 |
Poole BD, Niewold TB, Tsokos GC. Cytokines in Systemic Lupus Erythematosus 2011 Journal of Biomedicine and Biotechnology. 2012. PMID 22505810 DOI: 10.1155/2012/427824 |
0.322 |
|
| 2012 |
Crispín JC, Apostolidis SA, Rosetti F, Keszei M, Wang N, Terhorst C, Mayadas TN, Tsokos GC. Cutting edge: protein phosphatase 2A confers susceptibility to autoimmune disease through an IL-17-dependent mechanism. Journal of Immunology (Baltimore, Md. : 1950). 188: 3567-71. PMID 22422882 DOI: 10.4049/Jimmunol.1200143 |
0.43 |
|
| 2012 |
Lapchak PH, Ioannou A, Kannan L, Rani P, Dalle Lucca JJ, Tsokos GC. Platelet-associated CD40/CD154 mediates remote tissue damage after mesenteric ischemia/reperfusion injury. Plos One. 7: e32260. PMID 22384195 DOI: 10.1371/Journal.Pone.0032260 |
0.314 |
|
| 2012 |
Ghosh D, Tsokos GC, Kyttaris VC. c-Jun and Ets2 proteins regulate expression of spleen tyrosine kinase in T cells. Journal of Biological Chemistry. 287: 11833-11841. PMID 22354960 DOI: 10.1074/Jbc.M111.333997 |
0.407 |
|
| 2012 |
Recher M, Burns SO, de la Fuente MA, Volpi S, Dahlberg C, Walter JE, Moffitt K, Mathew D, Honke N, Lang PA, Patrizi L, Falet H, Keszei M, Mizui M, Csizmadia E, ... ... Tsokos GC, et al. B cell-intrinsic deficiency of the Wiskott-Aldrich syndrome protein (WASp) causes severe abnormalities of the peripheral B-cell compartment in mice. Blood. 119: 2819-28. PMID 22302739 DOI: 10.1182/Blood-2011-09-379412 |
0.348 |
|
| 2012 |
Moulton VR, Holcomb DR, Zajdel MC, Tsokos GC. Estrogen upregulates cyclic AMP response element modulator α expression and downregulates interleukin-2 production by human T lymphocytes. Molecular Medicine (Cambridge, Mass.). 18: 370-8. PMID 22281835 DOI: 10.2119/Molmed.2011.00506 |
0.409 |
|
| 2012 |
Lo MS, Tsokos GC. Treatment of systemic lupus erythematosus: new advances in targeted therapy. Annals of the New York Academy of Sciences. 1247: 138-52. PMID 22236448 DOI: 10.1111/J.1749-6632.2011.06263.X |
0.351 |
|
| 2012 |
Chatterjee M, Rauen T, Kis-Toth K, Kyttaris VC, Hedrich CM, Terhorst C, Tsokos GC. Increased expression of SLAM receptors SLAMF3 and SLAMF6 in systemic lupus erythematosus T lymphocytes promotes Th17 differentiation. Journal of Immunology (Baltimore, Md. : 1950). 188: 1206-12. PMID 22184727 DOI: 10.4049/Jimmunol.1102773 |
0.424 |
|
| 2012 |
Hedrich CM, Rauen T, Kis-Toth K, Kyttaris VC, Tsokos GC. cAMP-responsive Element Modulator α (CREMα) Suppresses IL-17F Protein Expression in T Lymphocytes from Patients with Systemic Lupus Erythematosus (SLE) Journal of Biological Chemistry. 287: 4715-4725. PMID 22184122 DOI: 10.1074/Jbc.M111.323261 |
0.357 |
|
| 2012 |
Grammatikos AP, Tsokos GC. Immunodeficiency and autoimmunity: lessons from systemic lupus erythematosus Trends in Molecular Medicine. 18: 101-108. PMID 22177735 DOI: 10.1016/J.Molmed.2011.10.005 |
0.337 |
|
| 2012 |
Ghosh D, Kis‐Toth K, Juang Y, Tsokos GC. CREMα suppresses spleen tyrosine kinase expression in normal but not systemic lupus erythematosus T cells. Arthritis & Rheumatism. 64: 799-807. PMID 21953500 DOI: 10.1002/Art.33375 |
0.398 |
|
| 2011 |
Ichinose K, Rauen T, Juang Y, Kis-Toth K, Mizui M, Koga T, Tsokos GC. Cutting Edge: Calcium/Calmodulin-Dependent Protein Kinase Type IV Is Essential for Mesangial Cell Proliferation and Lupus Nephritis Journal of Immunology. 187: 5500-5504. PMID 22031763 DOI: 10.4049/Jimmunol.1102357 |
0.36 |
|
| 2011 |
Rauen T, Hedrich CM, Juang Y, Tenbrock K, Tsokos GC. cAMP-responsive Element Modulator (CREM)α Protein Induces Interleukin 17A Expression and Mediates Epigenetic Alterations at the Interleukin-17A Gene Locus in Patients with Systemic Lupus Erythematosus Journal of Biological Chemistry. 286: 43437-43446. PMID 22025620 DOI: 10.1074/Jbc.M111.299313 |
0.419 |
|
| 2011 |
Hedrich CM, Rauen T, Tsokos GC. cAMP-responsive Element Modulator (CREM)α Protein Signaling Mediates Epigenetic Remodeling of the Human Interleukin-2 Gene IMPLICATIONS IN SYSTEMIC LUPUS ERYTHEMATOSUS Journal of Biological Chemistry. 286: 43429-43436. PMID 21976679 DOI: 10.1074/Jbc.M111.299339 |
0.403 |
|
| 2011 |
Yoshiya K, Lapchak PH, Thai TH, Kannan L, Rani P, Dalle Lucca JJ, Tsokos GC. Depletion of gut commensal bacteria attenuates intestinal ischemia/reperfusion injury. American Journal of Physiology. Gastrointestinal and Liver Physiology. 301: G1020-30. PMID 21903760 DOI: 10.1152/Ajpgi.00239.2011 |
0.311 |
|
| 2011 |
Apostolidis SA, Lieberman LA, Kis-Toth K, Crispín JC, Tsokos GC. The dysregulation of cytokine networks in systemic lupus erythematosus. Journal of Interferon and Cytokine Research. 31: 769-779. PMID 21877904 DOI: 10.1089/Jir.2011.0029 |
0.415 |
|
| 2011 |
Ioannou A, Lucca JD, Tsokos GC. Immunopathogenesis of ischemia/reperfusion-associated tissue damage. Clinical Immunology. 141: 3-14. PMID 21839685 DOI: 10.1016/J.Clim.2011.07.001 |
0.369 |
|
| 2011 |
Rauen T, Benedyk K, Juang Y, Kerkhoff C, Kyttaris VC, Roth J, Tsokos GC, Tenbrock K. A Novel Intronic cAMP Response Element Modulator (CREM) Promoter Is Regulated by Activator Protein-1 (AP-1) and Accounts for Altered Activation-induced CREM Expression in T Cells from Patients with Systemic Lupus Erythematosus Journal of Biological Chemistry. 286: 32366-32372. PMID 21757709 DOI: 10.1074/Jbc.M111.245811 |
0.433 |
|
| 2011 |
Crispín JC, Apostolidis SA, Finnell MI, Tsokos GC. Induction of PP2A Bβ, a regulator of IL-2 deprivation-induced T-cell apoptosis, is deficient in systemic lupus erythematosus. Proceedings of the National Academy of Sciences of the United States of America. 108: 12443-12448. PMID 21746932 DOI: 10.1073/Pnas.1103915108 |
0.421 |
|
| 2011 |
Tun-Kyi A, Finn G, Greenwood A, Nowak M, Lee TH, Asara JM, Tsokos GC, Fitzgerald K, Israel E, Li X, Exley M, Nicholson LK, Lu KP. Essential role for the prolyl isomerase Pin1 in Toll-like receptor signaling and type I interferon-mediated immunity. Nature Immunology. 12: 733-41. PMID 21743479 DOI: 10.1038/Ni.2069 |
0.313 |
|
| 2011 |
Kyttaris VC, Tsokos GC. Targeting lymphocyte signaling pathways as a therapeutic approach to systemic lupus erythematosus. Current Opinion in Rheumatology. 23: 449-453. PMID 21720246 DOI: 10.1097/Bor.0B013E328349A242 |
0.309 |
|
| 2011 |
Kis-Toth K, Szanto A, Thai TH, Tsokos GC. Cytosolic DNA-activated human dendritic cells are potent activators of the adaptive immune response. Journal of Immunology (Baltimore, Md. : 1950). 187: 1222-34. PMID 21709148 DOI: 10.4049/Jimmunol.1100469 |
0.382 |
|
| 2011 |
Tan W, Sunahori K, Zhao J, Deng Y, Kaufman KM, Kelly JA, Langefeld CD, Williams AH, Comeau ME, Ziegler JT, Marion MC, Bae SC, Lee JH, Lee JS, Chang DM, ... ... Tsokos GC, et al. Association of PPP2CA polymorphisms with systemic lupus erythematosus susceptibility in multiple ethnic groups. Arthritis and Rheumatism. 63: 2755-63. PMID 21590681 DOI: 10.1002/Art.30452 |
0.341 |
|
| 2011 |
Moulton VR, Tsokos GC. Abnormalities of T cell signaling in systemic lupus erythematosus Arthritis Research & Therapy. 13: 207-207. PMID 21457530 DOI: 10.1186/Ar3251 |
0.437 |
|
| 2011 |
Kyttaris VC, Zhang Z, Kampagianni O, Tsokos GC. Calcium signaling in systemic lupus erythematosus T cells: a treatment target. Arthritis and Rheumatism. 63: 2058-66. PMID 21437870 DOI: 10.1002/Art.30353 |
0.419 |
|
| 2011 |
Sunahori K, Juang Y, Kyttaris VC, Tsokos GC. Promoter Hypomethylation Results in Increased Expression of Protein Phosphatase 2A in T Cells from Patients with Systemic Lupus Erythematosus Journal of Immunology. 186: 4508-4517. PMID 21346232 DOI: 10.4049/Jimmunol.1000340 |
0.405 |
|
| 2011 |
Apostolidis S, Crispín J, Tsokos G. IL-17-producing T cells in lupus nephritis. Lupus. 20: 120-124. PMID 21303828 DOI: 10.1177/0961203310389100 |
0.321 |
|
| 2011 |
Ghiran IC, Zeidel ML, Shevkoplyas SS, Burns JM, Tsokos GC, Kyttaris VC. Systemic lupus erythematosus serum deposits C4d on red blood cells, decreases red blood cell membrane deformability, and promotes nitric oxide production. Arthritis and Rheumatism. 63: 503-12. PMID 21280005 DOI: 10.1002/Art.30143 |
0.344 |
|
| 2011 |
Chatterjee M, Kis-Toth K, Thai TH, Terhorst C, Tsokos GC. SLAMF6-driven co-stimulation of human peripheral T cells is defective in SLE T cells. Autoimmunity. 44: 211-8. PMID 21231893 DOI: 10.3109/08916934.2010.530627 |
0.419 |
|
| 2011 |
Juang Y, Rauen T, Wang Y, Ichinose K, Benedyk K, Tenbrock K, Tsokos GC. Transcriptional Activation of the cAMP-responsive Modulator Promoter in Human T Cells Is Regulated by Protein Phosphatase 2A-mediated Dephosphorylation of SP-1 and Reflects Disease Activity in Patients with Systemic Lupus Erythematosus Journal of Biological Chemistry. 286: 1795-1801. PMID 21097497 DOI: 10.1074/Jbc.M110.166785 |
0.402 |
|
| 2011 |
Ichinose K, Juang Y, Crispín JC, Kis-Toth K, Tsokos GC. Suppression of autoimmunity and organ pathology in lupus‐prone mice upon inhibition of calcium/calmodulin‐dependent protein kinase type IV Arthritis & Rheumatism. 63: 523-529. PMID 20954187 DOI: 10.1002/Art.30085 |
0.453 |
|
| 2011 |
Lu X, Li Y, Simovic MO, Peckham R, Wang Y, Tsokos GC, Dalle Lucca JJ. Decay-accelerating factor attenuates c-reactive protein-potentiated tissue injury after mesenteric ischemia/reperfusion Journal of Surgical Research. 167: e103-e115. PMID 20189588 DOI: 10.1016/J.Jss.2009.10.021 |
0.325 |
|
| 2011 |
Chen J, Crispín JC, Lucca JD, Tsokos GC. A novel inhibitor of the alternative pathway of complement attenuates intestinal ischemia/reperfusion-induced injury. Journal of Surgical Research. 167. PMID 19691988 DOI: 10.1016/J.Jss.2009.05.041 |
0.324 |
|
| 2011 |
Pamuk ON, Lapchak PH, Rani P, Pine P, Luca JJD, Tsokos GC. Thematic stream: systemic autoimmune disease OP2. Spleen Tyrosine Kinase Inhibition Prevents Tissue Damage after Ischaemia Reperfusion Injury Rheumatology. 50. DOI: 10.1093/Rheumatology/Ker092 |
0.325 |
|
| 2010 |
Poole BD, Niewold TB, Tsokos GC, Via CS. Cytokines in Systemic Lupus Erythematosus Biomed Research International. 2010: 735169-735169. PMID 21603232 DOI: 10.1155/2010/735169 |
0.356 |
|
| 2010 |
Pamuk ON, Tsokos GC. Spleen tyrosine kinase inhibition in the treatment of autoimmune, allergic and autoinflammatory diseases Arthritis Research & Therapy. 12: 222-222. PMID 21211067 DOI: 10.1186/Ar3198 |
0.366 |
|
| 2010 |
Lieberman LA, Tsokos GC. The IL-2 Defect in Systemic Lupus Erythematosus Disease Has an Expansive Effect on Host Immunity Biomed Research International. 2010: 740619-740619. PMID 20625413 DOI: 10.1155/2010/740619 |
0.361 |
|
| 2010 |
Crispín JC, Tsokos GC. Interleukin-17-producing T cells in lupus Current Opinion in Rheumatology. 22: 499-503. PMID 20592603 DOI: 10.1097/Bor.0B013E32833C62B0 |
0.372 |
|
| 2010 |
Pamuk ON, Lapchak PH, Rani P, Pine P, Lucca JJD, Tsokos GC. Spleen tyrosine kinase inhibition prevents tissue damage after ischemia-reperfusion American Journal of Physiology-Gastrointestinal and Liver Physiology. 299. PMID 20522642 DOI: 10.1152/Ajpgi.00198.2010 |
0.375 |
|
| 2010 |
Deng G, Liu L, Tsokos GC. Targeted tumor necrosis factor receptor I preligand assembly domain improves skin lesions in MRL/lpr mice Arthritis & Rheumatism. 62: 2424-2431. PMID 20506390 DOI: 10.1002/Art.27534 |
0.318 |
|
| 2010 |
Deng G, Liu L, Kyttaris VC, Tsokos GC. Lupus Serum IgG Induces Skin Inflammation through the TNFR1 Signaling Pathway Journal of Immunology. 184: 7154-7161. PMID 20483718 DOI: 10.4049/Jimmunol.0902514 |
0.341 |
|
| 2010 |
Crispín JC, Kyttaris VC, Terhorst C, Tsokos GC. T cells as therapeutic targets in SLE. Nature Reviews. Rheumatology. 6: 317-25. PMID 20458333 DOI: 10.1038/Nrrheum.2010.60 |
0.443 |
|
| 2010 |
Wang Y, Li Y, Dalle Lucca SL, Simovic M, Tsokos GC, Dalle Lucca JJ. Decay accelerating factor (CD55) protects neuronal cells from chemical hypoxia-induced injury Journal of Neuroinflammation. 7. PMID 20380727 DOI: 10.1186/1742-2094-7-24 |
0.308 |
|
| 2010 |
Crispín JC, Tsokos GC. IL-17 in systemic lupus erythematosus. Biomed Research International. 2010: 943254-943254. PMID 20379379 DOI: 10.1155/2010/943254 |
0.394 |
|
| 2010 |
Kyttaris VC, Zhang Z, Kuchroo VK, Oukka M, Tsokos GC. Cutting edge: IL-23 receptor deficiency prevents the development of lupus nephritis in C57BL/6-lpr/lpr mice. Journal of Immunology (Baltimore, Md. : 1950). 184: 4605-9. PMID 20308633 DOI: 10.4049/Jimmunol.0903595 |
0.363 |
|
| 2010 |
Deng G, Liu L, Bahjat FR, Pine PR, Tsokos GC. Suppression of skin and kidney disease by inhibition of spleen tyrosine kinase in lupus-prone mice. Arthritis & Rheumatism. 62: 2086-2092. PMID 20222110 DOI: 10.1002/Art.27452 |
0.356 |
|
| 2010 |
Crispín JC, Keenan BT, Finnell MD, Bermas BL, Schur P, Massarotti E, Karlson EW, Fitzgerald LM, Ergin S, Kyttaris VC, Tsokos GC, Costenbader KH. Expression of CD44 variant isoforms CD44v3 and CD44v6 is increased on T cells from patients with systemic lupus erythematosus and is correlated with disease activity. Arthritis and Rheumatism. 62: 1431-7. PMID 20213807 DOI: 10.1002/Art.27385 |
0.411 |
|
| 2010 |
Detre C, Keszei M, Romero X, Tsokos GC, Terhorst C. SLAM family receptors and the SLAM-associated protein (SAP) modulate T cell functions. Seminars in Immunopathology. 32: 157-71. PMID 20146065 DOI: 10.1007/S00281-009-0193-0 |
0.386 |
|
| 2010 |
Crispín JC, Liossis SC, Kis-Toth K, Lieberman LA, Kyttaris VC, Juang Y, Tsokos GC. Pathogenesis of human systemic lupus erythematosus: recent advances Trends in Molecular Medicine. 16: 47-57. PMID 20138006 DOI: 10.1016/J.Molmed.2009.12.005 |
0.359 |
|
| 2010 |
Moulton VR, Tsokos GC. Alternative Splicing Factor/Splicing Factor 2 Regulates the Expression of the ζ Subunit of the Human T Cell Receptor-associated CD3 Complex Journal of Biological Chemistry. 285: 12490-12496. PMID 20118245 DOI: 10.1074/Jbc.M109.091660 |
0.407 |
|
| 2010 |
Kis-Toth K, Tsokos GC. Dendritic cell function in lupus: Independent contributors or victims of aberrant immune regulation Autoimmunity. 43: 121-130. PMID 20102311 DOI: 10.3109/08916930903214041 |
0.348 |
|
| 2010 |
Ghosh D, Tsokos GC. Spleen tyrosine kinase: an Src family of non-receptor kinase has multiple functions and represents a valuable therapeutic target in the treatment of autoimmune and inflammatory diseases. Autoimmunity. 43: 48-55. PMID 20001666 DOI: 10.3109/08916930903374717 |
0.395 |
|
| 2009 |
Mayadas TN, Tsokos GC, Tsuboi N. Mechanisms of Immune Complex–Mediated Neutrophil Recruitment and Tissue Injury Circulation. 120: 2012-2024. PMID 19917895 DOI: 10.1161/Circulationaha.108.771170 |
0.359 |
|
| 2009 |
Crispín JC, Tsokos GC. Human TCR-αβ+ CD4− CD8− T Cells Can Derive from CD8+ T Cells and Display an Inflammatory Effector Phenotype Journal of Immunology. 183: 4675-4681. PMID 19734235 DOI: 10.4049/Jimmunol.0901533 |
0.425 |
|
| 2009 |
Zhang Z, Kyttaris VC, Tsokos GC. The role of IL-23/IL-17 axis in lupus nephritis. Journal of Immunology (Baltimore, Md. : 1950). 183: 3160-9. PMID 19657089 DOI: 10.4049/Jimmunol.0900385 |
0.368 |
|
| 2009 |
Nalbandian A, Crispín JC, Tsokos GC. Interleukin‐17 and systemic lupus erythematosus: current concepts Clinical and Experimental Immunology. 157: 209-215. PMID 19604260 DOI: 10.1111/J.1365-2249.2009.03944.X |
0.353 |
|
| 2009 |
Wu HY, Center EM, Tsokos GC, Weiner HL. Suppression of murine SLE by oral anti-CD3: Inducible CD4+CD25-LAP+ regulatory T cells control the expansion of IL-17+ follicular helper T cells Lupus. 18: 586-596. PMID 19433458 DOI: 10.1177/0961203308100511 |
0.391 |
|
| 2009 |
Kulik L, Fleming SD, Moratz C, Reuter JW, Novikov A, Chen K, Andrews KA, Markaryan A, Quigg RJ, Silverman GJ, Tsokos GC, Holers VM. Pathogenic natural antibodies recognizing annexin IV are required to develop intestinal ischemia-reperfusion injury. Journal of Immunology (Baltimore, Md. : 1950). 182: 5363-73. PMID 19380783 DOI: 10.4049/Jimmunol.0803980 |
0.332 |
|
| 2009 |
Chen J, Crispín JC, Tedder TF, Lucca JD, Tsokos GC. B cells contribute to ischemia/reperfusion-mediated tissue injury. Journal of Autoimmunity. 32: 195-200. PMID 19342197 DOI: 10.1016/J.Jaut.2009.02.021 |
0.354 |
|
| 2009 |
Ahlmann M, Varga G, Sturm K, Lippe R, Benedyk K, Viemann D, Scholzen T, Ehrchen J, Müller FU, Seidl M, Matus M, Tsokos GC, Roth J, Tenbrock K. The Cyclic AMP Response Element Modulator α Suppresses CD86 Expression and APC Function Journal of Immunology. 182: 4167-4174. PMID 19299714 DOI: 10.4049/Jimmunol.0802976 |
0.403 |
|
| 2009 |
Sunahori K, Juang Y, Tsokos GC. Methylation Status of CpG Islands Flanking a cAMP Response Element Motif on the Protein Phosphatase 2Acα Promoter Determines CREB Binding and Activity Journal of Immunology. 182: 1500-1508. PMID 19155497 DOI: 10.4049/Jimmunol.182.3.1500 |
0.338 |
|
| 2009 |
Edgerton C, Crispín JC, Moratz CM, Bettelli E, Oukka M, Simovic M, Zacharia A, Egan R, Chen J, Dalle Lucca JJ, Juang YT, Tsokos GC. IL-17 producing CD4+ T cells mediate accelerated ischemia/reperfusion-induced injury in autoimmunity-prone mice. Clinical Immunology (Orlando, Fla.). 130: 313-21. PMID 19058762 DOI: 10.1016/J.Clim.2008.09.019 |
0.384 |
|
| 2009 |
Crispín JC, Tsokos GC. Transcriptional regulation of IL-2 in health and autoimmunity. Autoimmunity Reviews. 8: 190-195. PMID 18723131 DOI: 10.1016/J.Autrev.2008.07.042 |
0.385 |
|
| 2008 |
Crispín JC, Oukka M, Bayliss G, Cohen RA, Van Beek CA, Stillman IE, Kyttaris VC, Juang YT, Tsokos GC. Expanded double negative T cells in patients with systemic lupus erythematosus produce IL-17 and infiltrate the kidneys. Journal of Immunology (Baltimore, Md. : 1950). 181: 8761-6. PMID 19050297 DOI: 10.4049/Jimmunol.181.12.8761 |
0.432 |
|
| 2008 |
Krishnan S, Juang YT, Chowdhury B, Magilavy A, Fisher CU, Nguyen H, Nambiar MP, Kyttaris V, Weinstein A, Bahjat R, Pine P, Rus V, Tsokos GC. Differential expression and molecular associations of Syk in systemic lupus erythematosus T cells. Journal of Immunology (Baltimore, Md. : 1950). 181: 8145-52. PMID 19018007 DOI: 10.4049/Jimmunol.181.11.8145 |
0.443 |
|
| 2008 |
Deng G, Tsokos GC. Cholera Toxin B Accelerates Disease Progression in Lupus-Prone Mice by Promoting Lipid Raft Aggregation Journal of Immunology. 181: 4019-4026. PMID 18768857 DOI: 10.4049/Jimmunol.181.6.4019 |
0.356 |
|
| 2008 |
Juang YT, Wang Y, Jiang G, Peng HB, Ergin S, Finnell M, Magilavy A, Kyttaris VC, Tsokos GC. PP2A dephosphorylates Elf-1 and determines the expression of CD3zeta and FcRgamma in human systemic lupus erythematosus T cells. Journal of Immunology (Baltimore, Md. : 1950). 181: 3658-64. PMID 18714041 DOI: 10.4049/Jimmunol.181.5.3658 |
0.417 |
|
| 2008 |
Fleming SD, Phillips LM, Lambris JD, Tsokos GC. Complement Component C5a Mediates Hemorrhage-Induced Intestinal Damage Journal of Surgical Research. 150: 196-203. PMID 18639891 DOI: 10.1016/J.Jss.2008.02.010 |
0.306 |
|
| 2008 |
Cohen RA, Bayliss G, Crispin JC, Kane-Wanger GF, Van Beek CA, Kyttaris VC, Avalos I, Yu CY, Tsokos GC, Stillman IE. T cells and in situ cryoglobulin deposition in the pathogenesis of lupus nephritis. Clinical Immunology (Orlando, Fla.). 128: 1-7. PMID 18565470 DOI: 10.1016/J.Clim.2008.04.004 |
0.395 |
|
| 2008 |
Moulton VR, Kyttaris VC, Juang YT, Chowdhury B, Tsokos GC. The RNA-stabilizing protein HuR regulates the expression of zeta chain of the human T cell receptor-associated CD3 complex. The Journal of Biological Chemistry. 283: 20037-44. PMID 18505733 DOI: 10.1074/Jbc.M710434200 |
0.385 |
|
| 2008 |
Tsokos GC. Calcium signaling in systemic lupus erythematosus lymphocytes and its therapeutic exploitation. Arthritis & Rheumatism. 58: 1216-1219. PMID 18438836 DOI: 10.1002/Art.23445 |
0.303 |
|
| 2008 |
Haymore BR, Mikita CP, Tsokos GC. Common variable immune deficiency (CVID) presenting as an autoimmune disease: role of memory B cells. Autoimmunity Reviews. 7: 309-312. PMID 18295735 DOI: 10.1016/J.Autrev.2007.11.024 |
0.328 |
|
| 2008 |
Crispín JC, Kyttaris VC, Juang Y, Tsokos GC. How signaling and gene transcription aberrations dictate the systemic lupus erythematosus T cell phenotype Trends in Immunology. 29: 110-115. PMID 18249583 DOI: 10.1016/J.It.2007.12.003 |
0.411 |
|
| 2008 |
Crispín JC, Tsokos GC. Novel molecular targets in the treatment of systemic lupus erythematosus. Autoimmunity Reviews. 7: 256-261. PMID 18190888 DOI: 10.1016/J.Autrev.2007.11.020 |
0.423 |
|
| 2008 |
Kulik L, Fleming SD, Moratz C, Quigg RJ, Silverman GJ, Tsokos GC, Holers VM. Pathogenic natural antibodies recognizing Annexin IV are required to develop intestinal ischaemia-reperfusion injury and are selected during development in a CR2/CD21-dependent manner Molecular Immunology. 45: 4110. DOI: 10.1016/J.Molimm.2008.08.046 |
0.304 |
|
| 2008 |
Moulton V, Perl M, Tsokos G. Sa.45. Alternative Splicing Factor/Splicing Factor 2 (ASF/SF2) Regulates the Expression of T Cell Receptor ζ chain Clinical Immunology. 127. DOI: 10.1016/J.Clim.2008.03.266 |
0.325 |
|
| 2007 |
Crispin JC, Kyttaris VC, Juang Y, Tsokos GC. Systemic lupus erythematosus: new molecular targets. Annals of the Rheumatic Diseases. 66. PMID 17934100 DOI: 10.1136/Ard.2007.078493 |
0.422 |
|
| 2007 |
Bergmann-Leitner ES, Duncan EH, Leitner WW, Neutzner A, Savranskaya T, Angov E, Tsokos GC. C3d-defined complement receptor-binding peptide p28 conjugated to circumsporozoite protein provides protection against Plasmodium berghei. Vaccine. 25: 7732-6. PMID 17931754 DOI: 10.1016/J.Vaccine.2007.08.030 |
0.313 |
|
| 2007 |
Juang Y, Sumibcay L, Tolnay M, Wang Y, Kyttaris VC, Tsokos GC. Elf-1 Binds to GGAA Elements on the FcRγ Promoter and Represses Its Expression Journal of Immunology. 179: 4884-4889. PMID 17878388 DOI: 10.4049/Jimmunol.179.7.4884 |
0.337 |
|
| 2007 |
Gibson HM, Hedgcock CJ, Aufiero BM, Wilson AJ, Hafner MS, Tsokos GC, Wong HK. Induction of the CTLA-4 gene in human lymphocytes is dependent on NFAT binding the proximal promoter. Journal of Immunology (Baltimore, Md. : 1950). 179: 3831-40. PMID 17785820 DOI: 10.4049/Jimmunol.179.6.3831 |
0.363 |
|
| 2007 |
Okoye FI, Krishnan S, Chandok MR, Tsokos GC, Farber DL. Proximal signaling control of human effector CD4 T cell function. Clinical Immunology (Orlando, Fla.). 125: 5-15. PMID 17692570 DOI: 10.1016/J.Clim.2007.07.002 |
0.393 |
|
| 2007 |
Kyttaris VC, Tsokos GC. Syk kinase as a treatment target for therapy in autoimmune diseases. Clinical Immunology. 124: 235-237. PMID 17662659 DOI: 10.1016/J.Clim.2007.06.005 |
0.328 |
|
| 2007 |
Tenbrock K, Juang Y-, Kyttaris VC, Tsokos GC. Altered signal transduction in SLE T cells Rheumatology. 46: 1525-1530. PMID 17586862 DOI: 10.1093/Rheumatology/Kem154 |
0.426 |
|
| 2007 |
Kiang JG, Bowman PD, Lu X, Li Y, Wu BW, Loh HH, Tsen KT, Tsokos GC. Geldanamycin inhibits hemorrhage-induced increases in caspase-3 activity: role of inducible nitric oxide synthase. Journal of Applied Physiology (Bethesda, Md. : 1985). 103: 1045-55. PMID 17525298 DOI: 10.1152/Japplphysiol.00100.2007 |
0.302 |
|
| 2007 |
Keith MP, Moratz C, Egan R, Zacharia A, Greidinger EL, Hoffman RW, Tsokos GC. Anti-ribonucleoprotein antibodies mediate enhanced lung injury following mesenteric ischemia/reperfusion in Rag-1(-/-) mice. Autoimmunity. 40: 208-16. PMID 17453720 DOI: 10.1080/08916930701262986 |
0.308 |
|
| 2007 |
Harada T, Kyttaris V, Li Y, Juang Y, Wang Y, Tsokos GC. Increased expression of STAT3 in SLE T cells contributes to enhanced chemokine-mediated cell migration. Autoimmunity. 40: 1-8. PMID 17364491 DOI: 10.1080/08916930601095148 |
0.429 |
|
| 2007 |
Keith MP, Moratz C, Tsokos GC. Anti-RNP immunity: implications for tissue injury and the pathogenesis of connective tissue disease. Autoimmunity Reviews. 6: 232-6. PMID 17317614 DOI: 10.1016/J.Autrev.2006.08.007 |
0.326 |
|
| 2007 |
Kyttaris VC, Wang Y, Juang YT, Weinstein A, Tsokos GC. Increased levels of NF-ATc2 differentially regulate CD154 and IL-2 genes in T cells from patients with systemic lupus erythematosus. Journal of Immunology (Baltimore, Md. : 1950). 178: 1960-6. PMID 17237447 DOI: 10.4049/Jimmunol.178.3.1960 |
0.409 |
|
| 2007 |
Li Y, Harada T, Juang YT, Kyttaris VC, Wang Y, Zidanic M, Tung K, Tsokos GC. Phosphorylated ERM is responsible for increased T cell polarization, adhesion, and migration in patients with systemic lupus erythematosus. Journal of Immunology (Baltimore, Md. : 1950). 178: 1938-47. PMID 17237445 DOI: 10.4049/Jimmunol.178.3.1938 |
0.429 |
|
| 2007 |
Liapis H, Tsokos GC. Pathology and immunology of lupus glomerulonephritis: can we bridge the two? International Urology and Nephrology. 39: 223-231. PMID 17219015 DOI: 10.1007/S11255-006-9170-X |
0.373 |
|
| 2007 |
Lopez-Santalla M, Krishnan S, Valeri AP, Aguilera-Montilla N, Fisher CU, Perez-Blas M, Gutierrez-Calvo A, Lasa I, Granell-Vicent J, Tsokos GC, Martin-Villa JM. FcRgamma chain does not replace CD3zeta chain in CD3zeta-deficient T lymphocytes of patients with gastric adenocarcinoma. Molecular Immunology. 44: 2400-5. PMID 17134755 DOI: 10.1016/J.Molimm.2006.10.012 |
0.379 |
|
| 2007 |
Moulton VR, Kyttaris VC, Juang Y, Tsokos GC. Post-Transcriptional Regulation of T Cell Receptor zeta Chain in Systemic Lupus Erythematosus Clinical Immunology. 123. DOI: 10.1016/J.Clim.2007.03.366 |
0.379 |
|
| 2006 |
Kyttaris VC, Krishnan S, Tsokos GC. Systems biology in systemic lupus erythematosus: integrating genes, biology and immune function. Autoimmunity. 39: 705-9. PMID 17178567 DOI: 10.1080/08916930601061363 |
0.391 |
|
| 2006 |
Bergmann-Leitner ES, Leitner WW, Tsokos GC. Complement 3d: from molecular adjuvant to target of immune escape mechanisms. Clinical Immunology (Orlando, Fla.). 121: 177-85. PMID 16914381 DOI: 10.1016/J.Clim.2006.07.001 |
0.33 |
|
| 2006 |
Wong HK, Tsokos GC. Fas (CD95) ligation inhibits activation of NF-κB by targeting p65-Rel A in a caspase-dependent manner Clinical Immunology. 121: 47-53. PMID 16765090 DOI: 10.1016/J.Clim.2006.04.572 |
0.339 |
|
| 2006 |
Krishnan S, Chowdhury B, Tsokos GC. Autoimmunity in systemic lupus erythematosus: integrating genes and biology. Seminars in Immunology. 18: 230-43. PMID 16713714 DOI: 10.1016/J.Smim.2006.03.011 |
0.337 |
|
| 2006 |
Katsiari CG, Tsokos GC. Transcriptional repression of interleukin-2 in human systemic lupus erythematosus. Autoimmunity Reviews. 5: 118-121. PMID 16431340 DOI: 10.1016/J.Autrev.2005.08.009 |
0.414 |
|
| 2006 |
Fleming SD, Tsokos GC. Complement, natural antibodies, autoantibodies and tissue injury Autoimmunity Reviews. 5: 89-92. PMID 16431334 DOI: 10.1016/J.Autrev.2005.09.006 |
0.314 |
|
| 2006 |
Katsiari CG, Tsokos GC. Systemic lupus erythematosus: From disease pathogenesis to therapy Drug Discovery Today: Disease Mechanisms. 3: 185-192. DOI: 10.1016/J.Ddmec.2006.05.007 |
0.347 |
|
| 2006 |
Lopez-Santalla M, Krishnan S, Valeri AP, Aguilera-Montilla N, Fisher CU, Perez-Blas M, Gutierrez-Calvo A, Lasa I, Granell-Vicent J, Tsokos GC, Martin-Villa JM. Erratum to “Defective CD3ζ chain expression in Herpesvirus saimiri (HVS)-derived T-cell lines in gastric adenocarcinoma” [Cell. Immunol. 238 (2005) 113–122] Cellular Immunology. 241: 113-114. DOI: 10.1016/J.Cellimm.2006.02.008 |
0.318 |
|
| 2005 |
Lopez-Santalla M, Krishnan S, Valeri AP, Aguilera-Montilla N, Fisher CU, Perez-Blas M, Gutierrez-Calvo A, Lasa I, Granell-Vicent J, Tsokos GC, Martin-Villa JM. Defective CD3zeta chain expression in Herpesvirus saimiri (HVS)-derived T-cell lines in gastric adenocarcinoma. Cellular Immunology. 238: 113-22. PMID 16616055 DOI: 10.1016/J.Cellimm.2006.02.007 |
0.345 |
|
| 2005 |
Kyttaris VC, Sfikakis PP, Juang Y, Tsokos GC. Gene therapy in systemic lupus erythematosus Current Gene Therapy. 5: 677-684. PMID 16457656 DOI: 10.2174/156652305774964703 |
0.36 |
|
| 2005 |
Kyttaris VC, Katsiari CG, Juang Y, Tsokos GC. New insights into the pathogenesis of systemic lupus erythematosus. Current Rheumatology Reports. 7: 469-475. PMID 16303108 DOI: 10.1007/S11926-005-0054-3 |
0.427 |
|
| 2005 |
Tenbrock K, Kyttaris VC, Ahlmann M, Ehrchen JM, Tolnay M, Melkonyan H, Mawrin C, Roth J, Sorg C, Juang Y, Tsokos GC. The cyclic AMP response element modulator regulates transcription of the TCR zeta-chain Journal of Immunology. 175: 5975-5980. PMID 16237091 DOI: 10.4049/Jimmunol.175.9.5975 |
0.345 |
|
| 2005 |
Katsiari CG, Kyttaris VC, Juang Y, Tsokos GC. Protein phosphatase 2A is a negative regulator of IL-2 production in patients with systemic lupus erythematosus Journal of Clinical Investigation. 115: 3193-3204. PMID 16224536 DOI: 10.1172/Jci24895 |
0.378 |
|
| 2005 |
Liossis SC, Tsokos GC. Monoclonal antibodies and fusion proteins in medicine The Journal of Allergy and Clinical Immunology. 116: 721-729. PMID 16210042 DOI: 10.1016/J.Jaci.2005.06.035 |
0.327 |
|
| 2005 |
Atkinson C, Song H, Lu B, Qiao F, Burns TA, Holers VM, Tsokos GC, Tomlinson S. Targeted complement inhibition by C3d recognition ameliorates tissue injury without apparent increase in susceptibility to infection. The Journal of Clinical Investigation. 115: 2444-53. PMID 16127466 DOI: 10.1172/Jci25208 |
0.321 |
|
| 2005 |
Krishnan S, Kiang JG, Fisher CU, Nambiar MP, Nguyen HT, Kyttaris VC, Chowdhury B, Rus V, Tsokos GC. Increased caspase-3 expression and activity contribute to reduced CD3zeta expression in systemic lupus erythematosus T cells. Journal of Immunology (Baltimore, Md. : 1950). 175: 3417-23. PMID 16116236 DOI: 10.4049/Jimmunol.175.5.3417 |
0.424 |
|
| 2005 |
Sfikakis PP, Boletis JN, Tsokos GC. Rituximab anti-B-cell therapy in systemic lupus erythematosus: pointing to the future. Current Opinion in Rheumatology. 17: 550-557. PMID 16093832 DOI: 10.1097/01.Bor.0000172798.26249.Fc |
0.379 |
|
| 2005 |
Kyttaris VC, Juang Y, Tsokos GC. Immune cells and cytokines in systemic lupus erythematosus: an update. Current Opinion in Rheumatology. 17: 518-522. PMID 16093827 DOI: 10.1097/01.Bor.0000170479.01451.Ab |
0.463 |
|
| 2005 |
Herndon TM, Pirone DM, Tsokos GC, Chen CS. T cell-to-T cell clustering enhances NF-kappaB activity by a PI3K signal mediated by Cbl-b and Rho. Biochemical and Biophysical Research Communications. 332: 1133-9. PMID 15922296 DOI: 10.1016/J.Bbrc.2005.05.064 |
0.383 |
|
| 2005 |
Juang Y, Wang Y, Solomou EE, Li Y, Mawrin C, Tenbrock K, Kyttaris VC, Tsokos GC. Systemic lupus erythematosus serum IgG increases CREM binding to the IL-2 promoter and suppresses IL-2 production through CaMKIV. Journal of Clinical Investigation. 115: 996-1005. PMID 15841182 DOI: 10.1172/Jci22854 |
0.389 |
|
| 2005 |
Chowdhury B, Tsokos CG, Krishnan S, Robertson J, Fisher CU, Warke RG, Warke VG, Nambiar MP, Tsokos GC. Decreased stability and translation of T cell receptor zeta mRNA with an alternatively spliced 3'-untranslated region contribute to zeta chain down-regulation in patients with systemic lupus erythematosus. The Journal of Biological Chemistry. 280: 18959-66. PMID 15743765 DOI: 10.1074/Jbc.M501048200 |
0.387 |
|
| 2005 |
Bergmann-Leitner ES, Scheiblhofer S, Weiss R, Duncan EH, Leitner WW, Chen D, Angov E, Khan F, Williams JL, Winter DB, Thalhamer J, Lyon JA, Tsokos GC. C3d binding to the circumsporozoite protein carboxy-terminus deviates immunity against malaria. International Immunology. 17: 245-55. PMID 15710912 DOI: 10.1093/Intimm/Dxh205 |
0.325 |
|
| 2005 |
Anderson J, Fleming SD, Rehrig S, Tsokos GC, Basta M, Shea-Donohue T. Intravenous immunoglobulin attenuates mesenteric ischemia-reperfusion injury Clinical Immunology. 114: 137-146. PMID 15639647 DOI: 10.1016/J.Clim.2004.08.018 |
0.308 |
|
| 2004 |
Tsokos GC. Exploring complement activation to develop biomarkers for systemic lupus erythematosus Arthritis & Rheumatism. 50: 3404-3407. PMID 15529386 DOI: 10.1002/Art.20602 |
0.314 |
|
| 2004 |
Fleming SD, Monestier M, Tsokos GC. Accelerated ischemia/reperfusion-induced injury in autoimmunity-prone mice. Journal of Immunology (Baltimore, Md. : 1950). 173: 4230-5. PMID 15356174 DOI: 10.4049/Jimmunol.173.6.4230 |
0.322 |
|
| 2004 |
Kyttaris VC, Juang Y, Tenbrock K, Weinstein A, Tsokos GC. Cyclic Adenosine 5′-Monophosphate Response Element Modulator Is Responsible for the Decreased Expression of c-fos and Activator Protein-1 Binding in T Cells from Patients with Systemic Lupus Erythematosus Journal of Immunology. 173: 3557-3563. PMID 15322221 DOI: 10.4049/Jimmunol.173.5.3557 |
0.395 |
|
| 2004 |
Kyttaris VC, Tsokos GC. T lymphocytes in systemic lupus erythematosus: an update. Current Opinion in Rheumatology. 16: 548-552. PMID 15314492 DOI: 10.1097/01.Bor.0000132646.55056.E0 |
0.451 |
|
| 2004 |
Nambiar MP, Krishnan S, Warke VG, Tsokos GC. TCR zeta-chain abnormalities in human systemic lupus erythematosus. Methods in Molecular Medicine. 102: 49-72. PMID 15286380 DOI: 10.1385/1-59259-805-6:049 |
0.412 |
|
| 2004 |
Nambiar MP, Krishnan S, Tsokos GC. T-cell signaling abnormalities in human systemic lupus erythematosus. Methods in Molecular Medicine. 102: 31-47. PMID 15286379 DOI: 10.1385/1-59259-805-6:031 |
0.432 |
|
| 2004 |
Tenbrock K, Tsokos GC. Transcriptional Regulation Of Interlekin 2 In Sle T Cells International Reviews of Immunology. 23: 333-345. PMID 15204092 DOI: 10.1080/08830180490452558 |
0.414 |
|
| 2004 |
Nambiar MP, Juang YT, Krishnan S, Tsokos GC. Dissecting the molecular mechanisms of TCR zeta chain downregulation and T cell signaling abnormalities in human systemic lupus erythematosus. International Reviews of Immunology. 23: 245-63. PMID 15204087 DOI: 10.1080/08830180490452602 |
0.406 |
|
| 2004 |
Tsokos GC. Immune cell signaling and gene transcription in human lupus: the time has come. International Reviews of Immunology. 23: 221-224. PMID 15204085 DOI: 10.1080/08830180490452530 |
0.32 |
|
| 2004 |
Tsokos GC. B cells, be gone--B-cell depletion in the treatment of rheumatoid arthritis. The New England Journal of Medicine. 350: 2546-2548. PMID 15201410 DOI: 10.1056/Nejmp048114 |
0.305 |
|
| 2004 |
Krishnan S, Nambiar MP, Warke VG, Fisher CU, Mitchell J, Delaney N, Tsokos GC. Alterations in lipid raft composition and dynamics contribute to abnormal T cell responses in systemic lupus erythematosus. Journal of Immunology (Baltimore, Md. : 1950). 172: 7821-31. PMID 15187166 DOI: 10.4049/Jimmunol.172.12.7821 |
0.402 |
|
| 2004 |
Elliott MR, Shanks RA, Khan IU, Brooks JW, Burkett PJ, Nelson BJ, Kyttaris V, Juang YT, Tsokos GC, Kammer GM. Down-regulation of IL-2 production in T lymphocytes by phosphorylated protein kinase A-RIIbeta. Journal of Immunology (Baltimore, Md. : 1950). 172: 7804-12. PMID 15187164 DOI: 10.4049/Jimmunol.172.12.7804 |
0.368 |
|
| 2004 |
Tsokos GC. Drugs, sun and T cells in lupus. Clinical and Experimental Immunology. 136: 191-193. PMID 15086379 DOI: 10.1111/J.1365-2249.2004.02455.X |
0.43 |
|
| 2004 |
Tsokos GC, Fleming SD. Autoimmunity, complement activation, tissue injury and reciprocal effects Current Directions in Autoimmunity. 7: 149-164. PMID 14719379 DOI: 10.1159/000075691 |
0.373 |
|
| 2004 |
Tsokos GC. Molecular and Cellular Pathogenesis of Systemic Lupus Erythematosus Japanese Journal of Clinical Immunology. 27: 220-221. DOI: 10.14906/Jscisho.27.0.220.0 |
0.31 |
|
| 2004 |
Tsokos G, Fleming S. Natural antibodies and autoantibodies bind to injured tissues, activate complement and cause organ damage Arthritis Research & Therapy. 6: 35-35. DOI: 10.1186/Ar1370 |
0.347 |
|
| 2003 |
Karpel-Massler G, Fleming SD, Kirschfink M, Tsokos GC. Human C1 esterase inhibitor attenuates murine mesenteric ischemia/reperfusion induced local organ injury Journal of Surgical Research. 115: 247-256. PMID 14697291 DOI: 10.1016/S0022-4804(03)00192-6 |
0.304 |
|
| 2003 |
Kiang JG, Warke VG, Tsokos GC. NaCN-induced chemical hypoxia is associated with altered gene expression Molecular and Cellular Biochemistry. 254: 211-216. PMID 14674700 DOI: 10.1023/A:1027363900317 |
0.36 |
|
| 2003 |
Tsokos GC, Tsokos M. The TRAIL to arthritis Journal of Clinical Investigation. 112: 1315-1317. PMID 14597758 DOI: 10.1172/Jci20297 |
0.336 |
|
| 2003 |
Elliott MR, Tolnay M, Tsokos GC, Kammer GM. Protein Kinase A Regulatory Subunit Type IIβ Directly Interacts with and Suppresses CREB Transcriptional Activity in Activated T Cells Journal of Immunology. 171: 3636-3644. PMID 14500661 DOI: 10.4049/Jimmunol.171.7.3636 |
0.425 |
|
| 2003 |
Krishnan S, Farber DL, Tsokos GC. T cell rewiring in differentiation and disease. Journal of Immunology (Baltimore, Md. : 1950). 171: 3325-31. PMID 14500623 DOI: 10.4049/Jimmunol.171.7.3325 |
0.395 |
|
| 2003 |
Fleming SD, Mastellos D, Karpel-Massler G, Shea-Donohue T, Lambris JD, Tsokos GC. C5a causes limited, polymorphonuclear cell-independent, mesenteric ischemia/reperfusion-induced injury Clinical Immunology. 108: 263-273. PMID 14499250 DOI: 10.1016/S1521-6616(03)00160-8 |
0.301 |
|
| 2003 |
Tsokos GC, Mitchell JP, Juang Y. T cell abnormalities in human and mouse lupus: intrinsic and extrinsic. Current Opinion in Rheumatology. 15: 542-547. PMID 12960478 DOI: 10.1097/00002281-200309000-00004 |
0.408 |
|
| 2003 |
Kiang JG, McClain DE, Warke VG, Krishnan S, Tsokos GC. Constitutive NO synthase regulates the Na+/Ca2+ exchanger in human T cells: role of [Ca2+]i and tyrosine phosphorylation. Journal of Cellular Biochemistry. 89: 1030-43. PMID 12874836 DOI: 10.1002/Jcb.10564 |
0.306 |
|
| 2003 |
Nambiar MP, Fisher CU, Warke VG, Krishnan S, Mitchell JP, Delaney N, Tsokos GC. Reconstitution of deficient T cell receptor zeta chain restores T cell signaling and augments T cell receptor/CD3-induced interleukin-2 production in patients with systemic lupus erythematosus. Arthritis and Rheumatism. 48: 1948-55. PMID 12847689 DOI: 10.1002/Art.11072 |
0.435 |
|
| 2003 |
Kyttaris VC, Tsokos GC. Uncovering the genetics of systemic lupus erythematosus: implications for therapy. American Journal of Pharmacogenomics. 3: 193-202. PMID 12814327 DOI: 10.2165/00129785-200303030-00005 |
0.327 |
|
| 2003 |
Tsokos GC, Nambiar MP, Tenbrock K, Juang YT. Rewiring the T-cell: signaling defects and novel prospects for the treatment of SLE. Trends in Immunology. 24: 259-63. PMID 12738420 DOI: 10.1016/S1471-4906(03)00100-5 |
0.402 |
|
| 2003 |
Tsokos GC, Nambiar MP, Juang YT. Activation of the Ets transcription factor Elf-1 requires phosphorylation and glycosylation: defective expression of activated Elf-1 is involved in the decreased TCR zeta chain gene expression in patients with systemic lupus erythematosus. Annals of the New York Academy of Sciences. 987: 240-5. PMID 12727645 DOI: 10.1111/J.1749-6632.2003.Tb06054.X |
0.369 |
|
| 2003 |
Krishnan S, Warke VG, Nambiar MP, Tsokos GC, Farber DL. The FcR gamma subunit and Syk kinase replace the CD3 zeta-chain and ZAP-70 kinase in the TCR signaling complex of human effector CD4 T cells. Journal of Immunology (Baltimore, Md. : 1950). 170: 4189-95. PMID 12682251 DOI: 10.4049/Jimmunol.170.8.4189 |
0.388 |
|
| 2003 |
Tenbrock K, Juang Y, Tolnay M, Tsokos GC. The Cyclic Adenosine 5′-Monophosphate Response Element Modulator Suppresses IL-2 Production in Stimulated T Cells by a Chromatin-Dependent Mechanism Journal of Immunology. 170: 2971-2976. PMID 12626549 DOI: 10.4049/Jimmunol.170.6.2971 |
0.358 |
|
| 2003 |
Nambiar MP, Fisher CU, Kumar A, Tsokos CG, Warke VG, Tsokos GC. Forced expression of the Fc receptor gamma-chain renders human T cells hyperresponsive to TCR/CD3 stimulation. Journal of Immunology (Baltimore, Md. : 1950). 170: 2871-6. PMID 12626537 DOI: 10.4049/Jimmunol.170.6.2871 |
0.412 |
|
| 2003 |
Warke VG, Nambiar MP, Krishnan S, Tenbrock K, Geller DA, Koritschoner NP, Atkins JL, Farber DL, Tsokos GC. Transcriptional activation of the human inducible nitric-oxide synthase promoter by Kruppel-like factor 6. The Journal of Biological Chemistry. 278: 14812-9. PMID 12590140 DOI: 10.1074/Jbc.M300787200 |
0.31 |
|
| 2003 |
Nambiar MP, Mitchell JP, Ceruti RP, Malloy MA, Tsokos GC. Prevalence of T cell receptor zeta chain deficiency in systemic lupus erythematosus. Lupus. 12: 46-51. PMID 12587826 DOI: 10.1191/0961203303Lu281Oa |
0.389 |
|
| 2003 |
Fleming SD, Anderson J, Wilson F, Shea-Donohue T, Tsokos GC. C5 is required for CD49d expression on neutrophils and VCAM expression on vascular endothelial cells following mesenteric ischemia/reperfusion Clinical Immunology. 106: 55-64. PMID 12584052 DOI: 10.1016/S1521-6616(02)00021-9 |
0.321 |
|
| 2003 |
Khan IU, Tsokos GC, Kammer GM. Abnormal B cell signal transduction in systemic lupus erythematosus. Current Directions in Autoimmunity. 6: 89-104. PMID 12408048 DOI: 10.1159/000066857 |
0.34 |
|
| 2003 |
Tsokos G, Fleming S. Natural antibodies and antiphospholipid antibodies bind to injured tissues, activate complement and cause tissue damage Arthritis Research & Therapy. 5: 101-101. DOI: 10.1186/Ar902 |
0.348 |
|
| 2002 |
Juang YT, Tenbrock K, Nambiar MP, Gourley MF, Tsokos GC. Defective production of functional 98-kDa form of Elf-1 is responsible for the decreased expression of TCR zeta-chain in patients with systemic lupus erythematosus. Journal of Immunology (Baltimore, Md. : 1950). 169: 6048-55. PMID 12421992 DOI: 10.4049/Jimmunol.169.10.6048 |
0.389 |
|
| 2002 |
Tenbrock K, Juang YT, Gourley MF, Nambiar MP, Tsokos GC. Antisense cyclic adenosine 5'-monophosphate response element modulator up-regulates IL-2 in T cells from patients with systemic lupus erythematosus. Journal of Immunology (Baltimore, Md. : 1950). 169: 4147-52. PMID 12370343 DOI: 10.4049/Jimmunol.169.8.4147 |
0.38 |
|
| 2002 |
Nambiar MP, Fisher CU, Enyedy EJ, Warke VG, Kumar A, Tsokos GC. Oxidative stress is involved in the heat stress-induced downregulation of TCR zeta chain expression and TCR/CD3-mediated [Ca(2+)](i) response in human T-lymphocytes. Cellular Immunology. 215: 151-61. PMID 12202152 DOI: 10.1016/S0008-8749(02)00006-0 |
0.34 |
|
| 2002 |
Fleming SD, Shea-Donohue T, Guthridge JM, Kulik L, Waldschmidt TJ, Gipson MG, Tsokos GC, Holers VM. Mice deficient in complement receptors 1 and 2 lack a tissue injury-inducing subset of the natural antibody repertoire. Journal of Immunology (Baltimore, Md. : 1950). 169: 2126-33. PMID 12165541 DOI: 10.4049/Jimmunol.169.4.2126 |
0.321 |
|
| 2002 |
Kammer GM, Perl A, Richardson BC, Tsokos GC. Abnormal T cell signal transduction in systemic lupus erythematosus Arthritis & Rheumatism. 46: 1139-1154. PMID 12115215 DOI: 10.1002/Art.10192 |
0.46 |
|
| 2002 |
Mitchell JP, Enyedy EJ, Nambiar MP, Lees A, Tsokos GC. Engagement of complement receptor 2 on the surface of B cells from patients with systemic lupus erythematosus contributes to the increased responsiveness to antigen stimulation. Lupus. 11: 299-303. PMID 12090564 DOI: 10.1191/0961203302Lu188Oa |
0.377 |
|
| 2002 |
Herndon TM, Juang Y, Solomou EE, Rothwell SW, Gourley MF, Tsokos GC. Direct transfer of p65 into T lymphocytes from systemic lupus erythematosus patients leads to increased levels of interleukin-2 promoter activity. Clinical Immunology. 103: 145-153. PMID 12027419 DOI: 10.1006/Clim.2002.5192 |
0.438 |
|
| 2002 |
Nambiar MP, Warke VG, Fisher CU, Tsokos GC. Effect of trichostatin A on human T cells resembles signaling abnormalities in T cells of patients with systemic lupus erythematosus: a new mechanism for TCR zeta chain deficiency and abnormal signaling. Journal of Cellular Biochemistry. 85: 459-69. PMID 11967985 DOI: 10.1002/Jcb.10160 |
0.415 |
|
| 2002 |
Kammer GM, Tsokos GC. Abnormal T Lymphocyte Signal Transduction in Systemic Lupus Erythematosus Current Directions in Autoimmunity. 5: 131-150. PMID 11826755 DOI: 10.1159/000060555 |
0.363 |
|
| 2002 |
Nambiar MP, Enyedy EJ, Fisher CU, Krishnan S, Warke VG, Gilliland WR, Oglesby RJ, Tsokos GC. Abnormal expression of various molecular forms and distribution of T cell receptor zeta chain in patients with systemic lupus erythematosus. Arthritis and Rheumatism. 46: 163-74. PMID 11817588 DOI: 10.1002/1529-0131(200201)46:1<163::Aid-Art10065>3.0.Co;2-J |
0.371 |
|
| 2001 |
Tsokos GC. A disease with a complex pathogenesis The Lancet. 358. PMID 11784614 DOI: 10.1016/S0140-6736(01)07077-5 |
0.465 |
|
| 2001 |
Rehrig S, Fleming SD, Anderson J, Guthridge JM, Rakstang J, McQueen CE, Holers VM, Tsokos GC, Shea-Donohue T. Complement inhibitor, complement receptor 1-related gene/protein y-Ig attenuates intestinal damage after the onset of mesenteric ischemia/reperfusion injury in mice Journal of Immunology. 167: 5921-5927. PMID 11698469 DOI: 10.4049/Jimmunol.167.10.5921 |
0.314 |
|
| 2001 |
Enyedy EJ, Mitchell JP, Nambiar MP, Tsokos GC. Defective FcgammaRIIb1 signaling contributes to enhanced calcium response in B cells from patients with systemic lupus erythematosus. Clinical Immunology (Orlando, Fla.). 101: 130-5. PMID 11683571 DOI: 10.1006/Clim.2001.5104 |
0.37 |
|
| 2001 |
Nambiar MP, Enyedy EJ, Fisher CU, Warke VG, Tsokos GC. High dose of dexamethasone upregulates TCR/CD3-induced calcium response independent of TCR zeta chain expression in human T lymphocytes. Journal of Cellular Biochemistry. 83: 401-13. PMID 11596109 DOI: 10.1002/Jcb.1238 |
0.36 |
|
| 2001 |
Warke VG, Krishnan S, Nambiar MP, Farber DL, Tsokos GC, Wong HK. Identification of differentially expressed genes in human memory (CD45RO+) CD4+ T lymphocytes. Immunological Investigations. 30: 87-101. PMID 11465674 DOI: 10.1081/Imm-100104018 |
0.316 |
|
| 2001 |
Nambiar MP, Enyedy EJ, Warke VG, Krishnan S, Dennis G, Wong HK, Kammer GM, Tsokos GC. T cell signaling abnormalities in systemic lupus erythematosus are associated with increased mutations/polymorphisms and splice variants of T cell receptor zeta chain messenger RNA. Arthritis and Rheumatism. 44: 1336-50. PMID 11407693 DOI: 10.1002/1529-0131(200106)44:6<1336::Aid-Art226>3.0.Co;2-8 |
0.372 |
|
| 2001 |
Krishnan S, Warke VG, Nambiar MP, Wong HK, Tsokos GC, Farber DL. Generation and biochemical analysis of human effector CD4 T cells: alterations in tyrosine phosphorylation and loss of CD3zeta expression. Blood. 97: 3851-9. PMID 11389026 DOI: 10.1182/Blood.V97.12.3851 |
0.414 |
|
| 2001 |
Enyedy EJ, Nambiar MP, Liossis SN, Dennis G, Kammer GM, Tsokos GC. Fc epsilon receptor type I gamma chain replaces the deficient T cell receptor zeta chain in T cells of patients with systemic lupus erythematosus. Arthritis and Rheumatism. 44: 1114-21. PMID 11352243 DOI: 10.1002/1529-0131(200105)44:5<1114::Aid-Anr192>3.0.Co;2-B |
0.435 |
|
| 2001 |
Solomou EE, Juang YT, Tsokos GC. Protein kinase C-θ participates in the activation of cyclic AMP-responsive element-binding protein and its subsequent binding to the -180 site of the IL-2 promoter in normal human T lymphocytes Journal of Immunology. 166: 5665-5674. PMID 11313407 DOI: 10.4049/Jimmunol.166.9.5665 |
0.363 |
|
| 2001 |
Herndon TM, Shan XC, Tsokos GC, Wange RL. ZAP-70 and SLP-76 Regulate Protein Kinase C-θ and NF-κB Activation in Response to Engagement of CD3 and CD28 Journal of Immunology. 166: 5654-5664. PMID 11313406 DOI: 10.4049/Jimmunol.166.9.5654 |
0.339 |
|
| 2001 |
Nambiar MP, Enyedy EJ, Fisher CU, Warke VG, Juang YT, Tsokos GC. Dexamethasone modulates TCR zeta chain expression and antigen receptor-mediated early signaling events in human T lymphocytes. Cellular Immunology. 208: 62-71. PMID 11277620 DOI: 10.1006/Cimm.2001.1761 |
0.37 |
|
| 2001 |
Nambiar MP, Enyedy EJ, Warke VG, Krishnan S, Dennis G, Kammer GM, Tsokos GC. Polymorphisms/mutations of TCR-zeta-chain promoter and 3' untranslated region and selective expression of TCR zeta-chain with an alternatively spliced 3' untranslated region in patients with systemic lupus erythematosus. Journal of Autoimmunity. 16: 133-42. PMID 11247639 DOI: 10.1006/Jaut.2000.0475 |
0.352 |
|
| 2001 |
Solomou EE, Juang Y, Gourley MF, Kammer GM, Tsokos GC. Molecular basis of deficient IL-2 production in T cells from patients with systemic lupus erythematosus. Journal of Immunology. 166: 4216-4222. PMID 11238674 DOI: 10.4049/Jimmunol.166.6.4216 |
0.403 |
|
| 2001 |
Mishra N, Tolnay M, Elliott, Brown, Tsokos G, Kammer G. The RIIbeta-subunit of protein kinase A (PKA) inhibits c-fos synthesis in T cells. Arthritis Research & Therapy. 3: 42. DOI: 10.1186/Ar211 |
0.339 |
|
| 2000 |
Tsokos GC, Kammer GM. Molecular aberrations in human systemic lupus erythematosus Molecular Medicine Today. 6: 418-424. PMID 11074367 DOI: 10.1016/S1357-4310(00)01798-6 |
0.326 |
|
| 2000 |
Nambiar MP, Fisher CU, Enyedy EJ, Warke VG, Krishnan S, Tsokos GC. Heat stress downregulates TCR zeta chain expression in human T lymphocytes. Journal of Cellular Biochemistry. 79: 416-26. PMID 10972979 DOI: 10.1002/1097-4644(20001201)79:3<416::Aid-Jcb70>3.0.Co;2-5 |
0.367 |
|
| 2000 |
Tolnay M, Tsokos GC. Serum regulates the expression of complement receptor 2 on human B cell lines. Immunopharmacology and Immunotoxicology. 22: 205-219. PMID 10952027 DOI: 10.3109/08923970009016416 |
0.332 |
|
| 2000 |
Mishra N, Khan IU, Tsokos GC, Kammer GM. Association of Deficient Type II Protein Kinase A Activity with Aberrant Nuclear Translocation of the RIIβ Subunit in Systemic Lupus Erythematosus T Lymphocytes Journal of Immunology. 165: 2830-2840. PMID 10946316 DOI: 10.4049/Jimmunol.165.5.2830 |
0.4 |
|
| 2000 |
Tsokos GC, Nepom GT. Gene therapy in the treatment of autoimmune diseases. The Journal of Clinical Investigation. 106: 181-3. PMID 10903332 DOI: 10.1172/Jci10575 |
0.342 |
|
| 2000 |
Goeckeritz BE, Lees A, Vos Q, Tsokos GC, Kuhlbusch K, Mond JJ. Enhanced and sustained activation of human B cells by anti-immunoglobulin conjugated to the EBV glycoprotein gp350. European Journal of Immunology. 30: 969-973. PMID 10741416 DOI: 10.1002/1521-4141(200003)30:3<969::Aid-Immu969>3.0.Co;2-A |
0.325 |
|
| 2000 |
Fleming S, Rehrig S, Guthridge J, Shea-Donohue T, Tsokos G, Holers V. Role of CR2- and CD19-regulated natural antibodies in intestinal ischemia reperfusion-induced injury Immunopharmacology. 49: 37. DOI: 10.1016/S0162-3109(00)80107-1 |
0.314 |
|
| 2000 |
Rehrig ST, Fleming SD, Guthridge J, Mulloy D, Ward D, Lawson S, Holers M, Shea-Donohue T, Tsokos G. Inhibition of ischemia reperfusion-induced intestinal injury and systemic inflammation by a novel complement regulatory protein Gastroenterology. 118. DOI: 10.1016/S0016-5085(00)85458-X |
0.313 |
|
| 1999 |
Kovacs B, Liossis S-C, Gist ID, Tsokos GC. Crosslinking of Fas/CD95 suppresses the CD3-mediated signaling events in Jurkat T cells by inhibiting the association of the T-cell receptor ζ chain with src-protein tyrosine kinases and ZAP70 Apoptosis. 4: 327-334. PMID 14634336 DOI: 10.1023/A:1009691120129 |
0.4 |
|
| 1999 |
Tsokos GC, Liossis SC. Immune cell signaling defects in lupus: activation, anergy and death Immunology Today. 20: 119-124. PMID 10203702 DOI: 10.1016/S0167-5699(98)01395-4 |
0.394 |
|
| 1998 |
Kammer GM, Tsokos GC. Emerging Concepts of the Molecular Basis for Estrogen Effects on T Lymphocytes in Systemic Lupus Erythematosus Clinical Immunology and Immunopathology. 89: 192-195. PMID 9837688 DOI: 10.1006/Clin.1998.4651 |
0.353 |
|
| 1998 |
Liossis SN, Hoffman RW, Tsokos GC. Abnormal early TCR/CD3-mediated signaling events of a snRNP-autoreactive lupus T cell clone. Clinical Immunology and Immunopathology. 88: 305-10. PMID 9743618 DOI: 10.1006/Clin.1998.4569 |
0.434 |
|
| 1998 |
Liossis SC, Sfikakis PP, Tsokos GC. Immune Cell Signaling Aberrations in Human Lupus Immunologic Research. 18: 27-39. PMID 9724847 DOI: 10.1007/Bf02786511 |
0.373 |
|
| 1998 |
Tolnay M, Tsokos GC. Complement receptor 2 in the regulation of the immune response. Clinical Immunology and Immunopathology. 88: 123-132. PMID 9714689 DOI: 10.1006/Clin.1998.4552 |
0.357 |
|
| 1998 |
Liossis SN, Ding XZ, Dennis GJ, Tsokos GC. Altered pattern of TCR/CD3-mediated protein-tyrosyl phosphorylation in T cells from patients with systemic lupus erythematosus. Deficient expression of the T cell receptor zeta chain. The Journal of Clinical Investigation. 101: 1448-57. PMID 9525988 DOI: 10.1172/Jci1457 |
0.447 |
|
| 1997 |
Liossis SC, Tsokos GC. Heat-shock of normal t-cells and T-cell lines downregulates the TCR/CD3-mediated cytoplasmic Ca2+ responses and the production of inositol trisphosphate. Immunopharmacology and Immunotoxicology. 19: 511-521. PMID 9436050 DOI: 10.3109/08923979709007672 |
0.367 |
|
| 1997 |
Kovacs B, Liossis SN, Dennis GJ, Tsokos GC. Increased expression of functional Fas-ligand in activated T cells from patients with systemic lupus erythematosus. Autoimmunity. 25: 213-21. PMID 9344329 DOI: 10.3109/08916939708994730 |
0.416 |
|
| 1997 |
Vassilopoulos D, Zurier RB, Rossetti RG, Tsokos GC. Gammalinolenic acid and dihomogammalinolenic acid suppress the CD3-mediated signal transduction pathway in human T cells. Clinical Immunology and Immunopathology. 83: 237-44. PMID 9175912 DOI: 10.1006/Clin.1997.4343 |
0.37 |
|
| 1997 |
Kovacs B, Patel A, Hershey JN, Dennis GJ, Kirschfink M, Tsokos GC. Antibodies against p53 in sera from patients with systemic lupus erythematosus and other rheumatic diseases. Arthritis and Rheumatism. 40: 980-2. PMID 9153564 DOI: 10.1002/Art.1780400531 |
0.317 |
|
| 1997 |
Sfikakis PP, Tsokos GC. Clinical use of the measurement of soluble cell adhesion molecules in patients with autoimmune rheumatic diseases. Clinical and Vaccine Immunology. 4: 241-246. DOI: 10.1128/Cdli.4.3.241-246.1997 |
0.31 |
|
| 1996 |
Liossis S-C, Kovacs B, Dennis G, Kammer GM, Tsokos GC. B Cells From Patients With Systemic Lupus Erythematosus Display Abnormal Antigen Receptor-Mediated Early Signal Transduction Events Journal of Clinical Investigation. 98: 2549-2557. PMID 8958217 DOI: 10.1172/Jci119073 |
0.398 |
|
| 1996 |
Kovacs B, Vassilopoulos D, Vogelgesang SA, Tsokos GC. Defective CD3-Mediated Cell Death in Activated T Cells from Patients with Systemic Lupus Erythematosus: Role of Decreased Intracellular TNF-α Clinical Immunology and Immunopathology. 81: 293-302. PMID 8938108 DOI: 10.1006/Clin.1996.0192 |
0.432 |
|
| 1996 |
Iliopoulos AG, Tsokos GC. Immunopathogenesis and spectrum of infections in systemiclupus erythematosus Seminars in Arthritis and Rheumatism. 25: 318-336. PMID 8778988 DOI: 10.1016/S0049-0172(96)80018-7 |
0.303 |
|
| 1996 |
Tsokos GC, Kovacs B, Sfikakis PP, Theocharis S, Vogelgesang S, Via CS. Defective antigen‐presenting cell function in patients with systemic lupus erythematosus: Role of the B7‐1 (CD80) costimulatory molecule Arthritis & Rheumatism. 39: 600-609. PMID 8630108 DOI: 10.1002/Art.1780390409 |
0.396 |
|
| 1996 |
Sfikakis PP, Souliotis VL, Katsilambros N, Markakis K, Vaiopoulos G, Tsokos GC, Panayiotidis P. Downregulation of Interleukin-2 and α-Chain Interleukin-2 Receptor Biosynthesis by Cisplatin in Human Peripheral Lymphocytes Clinical Immunology and Immunopathology. 79: 43-49. PMID 8612350 DOI: 10.1006/Clin.1996.0049 |
0.355 |
|
| 1995 |
Theocharis S, Sfikakis PP, Lipnick RN, Klipple GL, Steinberg AD, Tsokos GC. Characterization of in vivo mutated T cell clones from patients with systemic lupus erythematosus. Clinical Immunology and Immunopathology. 74: 135-142. PMID 7828367 DOI: 10.1006/Clin.1995.1020 |
0.406 |
|
| 1995 |
Vassilopoulos D, Smallridge RC, Tsokos GC. Effects of an aminosteroid inhibitor of phospholipase C-dependent processes on the TCR-mediated signal transduction pathway in human T cells. Clinical Immunology and Immunopathology. 77: 59-68. PMID 7554485 DOI: 10.1016/0090-1229(95)90137-X |
0.42 |
|
| 1995 |
Sfikakis PP, Zografou A, Viglis V, Iniotaki‐Theodoraki A, Piskontaki I, Tsokos GC, Sfikakis P, Choremi‐Papadopoulou H. Cd28 expression on t cell subsets in vivo and cd28-mediated t cell response in vitro in patients with rheumatoid arthritis Arthritis & Rheumatism. 38: 649-654. PMID 7538295 DOI: 10.1002/Art.1780380512 |
0.384 |
|
| 1994 |
Tsokos GC, Kovacs B, Liossis SC. Lymphocytes, cytokines, inflammation, and immune trafficking. Current Opinion in Rheumatology. 9: 380-386. PMID 8519609 DOI: 10.1097/00002281-199509000-00003 |
0.464 |
|
| 1994 |
Sfikakis PP, Tesar J, Theocharis S, Klipple G, Tsokos GC. Increased frequency of in vivo hprt gene-mutated T cells in the peripheral blood of patients with systemic sclerosis. Annals of the Rheumatic Diseases. 53: 122-127. PMID 8129457 DOI: 10.1136/Ard.53.2.122 |
0.403 |
|
| 1994 |
Vaiopoulos G, Sfikakis PP, Kapsimali V, Boki K, Panayiotidis P, Aessopos A, Tsokos GC, Kaklamanis P. The association of systemic lupus erythematosus and myasthenia gravis. Postgraduate Medical Journal. 70: 741-745. PMID 7831174 DOI: 10.1136/Pgmj.70.828.741 |
0.336 |
|
| 1994 |
Sfikakis PP, Oglesby R, Sfikakis P, Tsokos GC. B7/BB1 provides an important costimulatory signal for CD3-mediated T lymphocyte proliferation in patients with systemic lupus erythematosus (SLE). Clinical and Experimental Immunology. 96: 8-14. PMID 7512010 DOI: 10.1111/J.1365-2249.1994.Tb06221.X |
0.44 |
|
| 1993 |
Lipnick RN, Sfikakis PP, Klipple GL, Tsokos GC. Elevated Soluble CD8 Antigen and Soluble Interleukin-2 Receptors in the Sera of Patients with Juvenile Rheumatoid Arthritis Clinical Immunology and Immunopathology. 68: 64-67. PMID 8513595 DOI: 10.1006/Clin.1993.1096 |
0.319 |
|
| 1993 |
Sfikakis PP, Tesar J, Baraf H, Lipnick R, Klipple G, Tsokos GC. Circulating intercellular adhesion molecule-1 in patients with systemic sclerosis Clinical Immunology and Immunopathology. 68: 88-92. PMID 8099861 DOI: 10.1006/Clin.1993.1100 |
0.324 |
|
| 1992 |
Tsokos GC. Pathogenesis of human systemic lupus erythematosus. Introduction. Clinical Immunology and Immunopathology. 63: 3. PMID 1591879 DOI: 10.1016/0090-1229(92)90081-X |
0.301 |
|
| 1992 |
Spitzer RE, Stitzel AE, Tsokos GC. Study of the idiotypic response to autoantibody to the alternative pathway C3/C5 convertase in normal individuals, patients with membranoproliferative glomerulonephritis, and experimental animals. Clinical Immunology and Immunopathology. 62: 291-294. PMID 1541054 DOI: 10.1016/0090-1229(92)90105-W |
0.319 |
|
| 1991 |
Thyphronitis G, Banchereau J, Heusser C, Tsokos GC, Levine AD, Finkelman FD. Kinetics of interleukin-4 induction and interferon-γ inhibition of IgE secretion by Epstein-Barr virus-infected human peripheral blood B cells Cellular Immunology. 133: 408-419. PMID 1849800 DOI: 10.1016/0008-8749(91)90114-Q |
0.333 |
|
| 1990 |
Spitzer RE, Stitzel AE, Tsokos GC. Evidence that production of autoantibody to the alternative pathway C3 convertase is a normal physiologic event. The Journal of Pediatrics. 116. PMID 2329411 DOI: 10.1016/S0022-3476(05)82711-8 |
0.335 |
|
| 1990 |
Boumpas DT, Eleftheriades EG, Molina R, Barez S, Atkinson J, Older SA, Balow JE, Tsokos GC. C-MYC proto-oncogene expression in peripheral blood mononuclear cells from patients with primary Sjögren's syndrome Arthritis and Rheumatism. 33: 49-56. PMID 2302267 DOI: 10.1002/Art.1780330106 |
0.301 |
|
| 1990 |
Rajagopalan S, Zordan T, Tsokos GC, Datta SK. Pathogenic anti-DNA autoantibody-inducing T helper cell lines from patients with active lupus nephritis: isolation of CD4-8- T helper cell lines that express the gamma delta T-cell antigen receptor. Proceedings of the National Academy of Sciences of the United States of America. 87: 7020-7024. PMID 2144899 DOI: 10.1073/Pnas.87.18.7020 |
0.424 |
|
| 1990 |
Kinoshita T, Thyphronitis G, Tsokos GC, Finkelman FD, Hong K, Sakai H, Inoue K. Characterization of murine complement receptor type 2 and its immunological cross-reactivity with type 1 receptor International Immunology. 2: 651-659. PMID 1703784 DOI: 10.1093/Intimm/2.7.651 |
0.307 |
|
| 1990 |
Spitzer RE, Stitzel AE, Tsokos GC. Production of IgG and IgM autoantibody to the alternative pathway C3 convertase in normal individuals and patients with membranoproliferative glomerulonephritis Clinical Immunology and Immunopathology. 57: 10-18. PMID 1697516 DOI: 10.1016/0090-1229(90)90018-L |
0.309 |
|
| 1990 |
Pillemer SR, Tsokos GC, Barbieri SA, Balow JE, Golding B. The CR2 receptor (CD21) shows increased expression in the more differentiated cells of an antigen-specific B cell line. Cellular Immunology. 125: 386-395. PMID 1688740 DOI: 10.1016/0008-8749(90)90093-7 |
0.348 |
|
| 1989 |
Thyphronitis G, Tsokos GC, June CH, Levine AD, Finkelman FD. IgE secretion by Epstein-Barr virus-infected purified human B lymphocytes is stimulated by interleukin 4 and suppressed by interferon γ Proceedings of the National Academy of Sciences of the United States of America. 86: 5580-5584. PMID 2546158 DOI: 10.1073/Pnas.86.14.5580 |
0.337 |
|
| 1989 |
Eleftheriades EG, Boumpas DT, Balow JE, Tsokos GC. Transcriptional and post-transcriptional mechanisms are responsible for the increased expression of c-myc protooncogene in lymphocytes from patients with systemic lupus erythematosus. Clinical Immunology and Immunopathology. 52: 507-515. PMID 2474397 DOI: 10.1016/0090-1229(89)90163-3 |
0.309 |
|
| 1988 |
Hiramatsu M, Tsokos GC. A factor activating complement via the alternative pathway in the supernatants of B cell lines transformed by Epstein-Barr virus and in sera obtained from patients with systemic lupus erythematosus. International Archives of Allergy and Immunology. 86: 209-214. PMID 2839425 DOI: 10.1159/000234573 |
0.333 |
|
| 1988 |
Tsokos GC, Inghirami G, Pillemer SR, Mavridis A, Magilavy DB. Immunoregulatory aberrations in patients with polyarticular juvenile rheumatoid arthritis. Clinical Immunology and Immunopathology. 47: 62-74. PMID 2832112 DOI: 10.1016/0090-1229(88)90145-6 |
0.41 |
|
| 1988 |
Hiramatsu M, Tsokos GC. Epstein-Barr virus transformed B cell lines derived from patients with systemic lupus erythematosus produce a nephritic factor of the classical complement pathway. Clinical Immunology and Immunopathology. 46: 91-99. PMID 2826058 DOI: 10.1016/0090-1229(88)90009-8 |
0.371 |
|
| 1987 |
Balow JE, Austin HA, Tsokos GC, Antonovych TT, Steinberg AD, Klippel JH. NIH conference. Lupus nephritis. Annals of Internal Medicine. 106: 79-94. PMID 3789582 DOI: 10.7326/0003-4819-106-1-79 |
0.341 |
|
| 1987 |
Tsokos GC, Mavridis A, Inghirami G, Pillemer SR, Emery HM, Magilavy DB. Cellular immunity in patients with systemic juvenile rheumatoid arthritis. Clinical Immunology and Immunopathology. 42: 86-92. PMID 3539432 DOI: 10.1016/0090-1229(87)90175-9 |
0.435 |
|
| 1987 |
Baxevanis CN, Reclos GJ, Papamichail M, Tsokos GC. Prothymosin α Restores the Depressed Autologous and Allogeneic Mixed Lymphocyte Responses in Patients with Systemic Lupus Erythematosus Immunopharmacology and Immunotoxicology. 9: 429-440. PMID 2963855 DOI: 10.3109/08923978709035224 |
0.367 |
|
| 1986 |
Tsokos GC, Tsokos M, Riche NGHl, Klippel JH. A clinical and pathologic study of cerebrovascular disease in patients with systemic lupus erythematosus Seminars in Arthritis and Rheumatism. 16: 70-78. PMID 3749898 DOI: 10.1016/0049-0172(86)90041-7 |
0.32 |
|
| 1986 |
Tsokos GC, Smith PL, Balow JE. Development of hypogammaglobulinemia in a patient with systemic lupus erythematosus The American Journal of Medicine. 81: 1081-1084. PMID 3541592 DOI: 10.1016/0002-9343(86)90413-4 |
0.312 |
|
| 1986 |
Brickman CM, Tsokos GC, Chused TM, Balow JE, Lawley TJ, Santaella M, Hammer CH, Linton GF, Frank MM. Immunoregulatory disorders associated with hereditary angioedema. II. Serologic and cellular abnormalities. The Journal of Allergy and Clinical Immunology. 77: 758-67. PMID 3486201 DOI: 10.1016/0091-6749(86)90425-2 |
0.422 |
|
| 1986 |
Brickman CM, Tsokos GC, Balow JE, Lawley TJ, Santaella M, Hammer CH, Frank MM. Immunoregulatory disorders associated with hereditary angioedema. I. Clinical manifestations of autoimmune disease. The Journal of Allergy and Clinical Immunology. 77: 749-57. PMID 3084606 DOI: 10.1016/0091-6749(86)90424-0 |
0.327 |
|
| 1986 |
Boumpas DT, Popovic M, Mann DL, Balow JE, Tsokos GC. Type C retroviruses of the human T cell leukemia family are not evident in patients with systemic lupus erythematosus. Arthritis & Rheumatism. 29: 185-188. PMID 3006702 DOI: 10.1002/Art.1780290205 |
0.361 |
|
| 1986 |
Tsokos GC, Inghirami G, Lambris JD. Regulation of human cytotoxic responses by complement: C3, C3b and C3d preparations enhance human allogeneic cytotoxic responses. Immunopharmacology and Immunotoxicology. 8: 529-541. PMID 2949021 DOI: 10.3109/08923978609026504 |
0.313 |
|
| 1986 |
Tsokos GC, Boumpas DT, Smith PL, Djeu JY, Balow JE, Rook AH. Deficient γ-interferon production in patients with systemic lupus erythematosus Arthritis & Rheumatism. 29: 1210-1215. PMID 2429672 DOI: 10.1002/Art.1780291005 |
0.328 |
|
| 1986 |
Boumpas DT, Tsokos GC, Mann DL, Eleftheriades EG, Harris CC, Mark GE. Increased proto‐oncogene expression in peripheral blood lymphocytes from patients with systemic lupus erythematosus and other autoimmune diseases Arthritis & Rheumatism. 29: 755-760. PMID 2424462 DOI: 10.1002/Art.1780290608 |
0.398 |
|
| 1985 |
Tsokos GC, Smith PL, Christian CB, Lipnick RN, Balow JE, Djeu JY. Interleukin-2 restores the depressed allogeneic cell-mediated lympholysis and natural killer cell activity in patients with systemic lupus erythematosus. Clinical Immunology and Immunopathology. 34: 379-386. PMID 3156017 DOI: 10.1016/0090-1229(85)90186-2 |
0.356 |
|
| 1985 |
Boumpas DT, Hooks JJ, Popovic M, Tsokos GC, Mann DL. Human T-cell leukemia/lymphoma virus I and/or Epstein-Barr virus-infected B-cell lines spontaneously produce acid-labile α-interferon Journal of Clinical Immunology. 5: 340-344. PMID 2997264 DOI: 10.1007/Bf00918253 |
0.326 |
|
| 1985 |
Aguado MT, Lambris JD, Tsokos GC, Burger R, Bitter-Suermann D, Tamerius JD, Dixon FJ, Theofilopoulos AN. Monoclonal antibodies against complement 3 neoantigens for detection of immune complexes and complement activation. Relationship between immune complex levels, state of C3, and numbers of receptors for C3b. The Journal of Clinical Investigation. 76: 1418-26. PMID 2932466 DOI: 10.1172/Jci112119 |
0.322 |
|
| 1984 |
Lipnick RN, Balow JE, Tsokos GC. Lymphocyte subpopulations in patients with systemic lupus erythematosus Clinical Immunology and Immunopathology. 31: 181-190. PMID 6609037 DOI: 10.1016/0090-1229(84)90238-1 |
0.412 |
|
| 1984 |
Tsokos GC, Balow JE. Cellular Immune Responses in Systemic Lupus Erythematosus Progress in Allergy. 35: 93-161. DOI: 10.1159/000409413 |
0.322 |
|
| 1983 |
Tsokos GC, Christian CB, Balow JE. Induction of monocytic suppression after stimulation of peripheral human mononuclear cells with staphylococcal protein A and Staphylococcus aureus Cellular Immunology. 78: 144-151. PMID 6342815 DOI: 10.1016/0008-8749(83)90267-8 |
0.354 |
|
| 1983 |
Tsokos GC, Balow JE. Phenotypes of T lymphocytes in systemic lupus erythematosus: decreased cytotoxic/suppressor subpopulation is associated with deficient allogeneic cytotoxic responses rather than with concanavalin A-induced suppressor cells. Clinical Immunology and Immunopathology. 26: 267-276. PMID 6223747 DOI: 10.1016/0090-1229(83)90145-9 |
0.421 |
|
| 1982 |
Rook AH, Tsokos GC, Quinnan GV, Balow JE, Ramsey KM, Stocks N, Phelan MA, Djeu JY. Cytotoxic antibodies to natural killer cells in systemic lupus erythematosus Clinical Immunology and Immunopathology. 24: 179-185. PMID 6981481 DOI: 10.1016/0090-1229(82)90229-X |
0.38 |
|
| 1981 |
Tsokos GC, Balow JE. Cytotoxic responses to alloantigens in systemic lupus erythematosus. Journal of Clinical Immunology. 1: 208-216. PMID 19338096 DOI: 10.1007/Bf00915138 |
0.336 |
|
| 1981 |
Tsokos GC, Balow JE. Spontaneous and pokeweed mitogen-induced plaque-forming cells in systemic lupus erythematosus. Clinical Immunology and Immunopathology. 21: 172-183. PMID 7028331 DOI: 10.1016/0090-1229(81)90206-3 |
0.418 |
|
| 1981 |
Tsokos GC, Balow JE. Suppressor cells generated from human peripheral mononuclear cells by stimulation with pokeweed mitogen Cellular Immunology. 65: 221-229. DOI: 10.1016/0008-8749(81)90069-1 |
0.354 |
|
| 1981 |
Tsokos GC, Moutsopoulos HM, Steinberg AD. Muscle involvement in systemic lupus erythematosus. Jama. 246: 766-768. DOI: 10.1001/Jama.1981.03320070050025 |
0.304 |
|
| 1980 |
Tsokos G, Mandyla H, Xanthou M, Papamichail M. Chlorpromazine and lidocaine inhibit antibody-dependent cell-mediated cytotoxicity but not erythrocyte antibody rosette formation. International Archives of Allergy and Immunology. 61: 344-346. PMID 7353905 DOI: 10.1159/000232457 |
0.312 |
|
| 1980 |
Papamichail M, Tsokos G, Tsawdaroglou N, Sekeris CE. Immunocytochemical demonstration of glucocorticoid receptors in different cell types and their translocation from the cytoplasm to the cell nucleus in the presence of dexamethasone. Experimental Cell Research. 125: 490-3. PMID 6986277 DOI: 10.1016/0014-4827(80)90144-5 |
0.304 |
|
| 1980 |
Tsokos G, Papamichail M, Fessas P. A Subpopulation of Lymphocytes with T and B Cell Characteristics Acta Haematologica. 63: 88-93. PMID 6768218 DOI: 10.1159/000207376 |
0.396 |
|
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