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Aimee Edinger - Publications

Affiliations: 
Biological Sciences - Ph.D. University of California, Irvine, Irvine, CA 
Area:
Cell Biology
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38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Vöing K, Michgehl U, Mertens ND, Picciotto C, Maywald ML, Goretzko J, Waimann S, Gilhaus K, Rogg M, Schell C, Klingauf J, Tsytsyura Y, Hansen U, van Marck V, Edinger AL, et al. Disruption of the Rab7-Dependent Final Common Pathway of Endosomal and Autophagic Processing Results in a Severe Podocytopathy. Journal of the American Society of Nephrology : Jasn. PMID 37022133 DOI: 10.1681/ASN.0000000000000126  0.445
2020 Bachollet SPJT, Vece V, McCracken AN, Finicle BT, Selwan E, Ben Romdhane N, Dahal A, Ramirez C, Edinger AL, Hanessian S. Synthetic Sphingolipids with 1,2-Pyridazine Appendages Improve Antiproliferative Activity in Human Cancer Cell Lines. Acs Medicinal Chemistry Letters. 11: 686-690. PMID 32435371 DOI: 10.1021/Acsmedchemlett.9B00553  0.307
2020 Jayashankar V, Edinger AL. Macropinocytosis confers resistance to therapies targeting cancer anabolism. Nature Communications. 11: 1121. PMID 32111826 DOI: 10.1038/s41467-020-14928-3  0.331
2020 Kemp JA, Keebaugh A, Edson JA, Chow D, Kleinman MT, Chew YC, McCracken AN, Edinger AL, Kwon YJ. Biocompatible Chemotherapy for Leukemia by Acid-Cleavable, PEGylated FTY720. Bioconjugate Chemistry. PMID 31986014 DOI: 10.1021/Acs.Bioconjchem.9B00822  0.421
2019 Kubiniok P, Finicle BT, Piffaretti F, McCracken AN, Perryman M, Hanessian S, Edinger AL, Thibault P. Dynamic Phosphoproteomics Uncovers Signaling Pathways Modulated by Anti-oncogenic Sphingolipid Analogs. Molecular & Cellular Proteomics : McP. 18: 408-422. PMID 33431118 DOI: 10.1074/mcp.RA118.001053  0.46
2019 Cable J, Finley L, Tu BP, Patti GJ, Oliver TG, Vardhana S, Mana M, Ericksen R, Khare S, DeBerardinis R, Stockwell BR, Edinger A, Haigis M, Kaelin W. Leveraging insights into cancer metabolism-a symposium report. Annals of the New York Academy of Sciences. PMID 31792987 DOI: 10.1111/Nyas.14274  0.452
2019 Garsi JB, Vece V, Sernissi L, Auger-Morin C, Hanessian S, McCracken AN, Selwan E, Ramirez C, Dahal A, Romdhane NB, Finicle BT, Edinger AL. Design, synthesis and anticancer activity of constrained sphingolipid-phenoxazine/phenothiazine hybrid constructs targeting protein phosphatase 2A. Bioorganic & Medicinal Chemistry Letters. PMID 31383588 DOI: 10.1016/J.Bmcl.2019.07.023  0.316
2018 Kubiniok P, Finicle BT, Piffaretti F, McCracken AN, Perryman M, Hanessian S, Edinger AL, Thibault P. Dynamic phosphoproteomics uncovers signaling pathways modulated by anti-neoplastic sphingolipid analogs. Molecular & Cellular Proteomics : McP. PMID 30482847 DOI: 10.1074/Mcp.Ra118.001053  0.46
2018 Finicle BT, Jayashankar V, Edinger AL. Nutrient scavenging in cancer. Nature Reviews. Cancer. PMID 30097614 DOI: 10.1038/s41568-018-0048-x  0.441
2018 Finicle BT, Ramirez MU, Liu G, Selwan EM, McCracken AN, Yu J, Joo Y, Nguyen J, Ou K, Ghosh Roy S, Mendoza VD, Corrales DV, Edinger AL. Sphingolipids inhibit endosomal recycling of nutrient transporters by inactivating ARF6. Journal of Cell Science. PMID 29848659 DOI: 10.1242/jcs.213314  0.545
2016 Jaber N, Mohd-Naim N, Wang Z, DeLeon JL, Kim S, Zhong H, Sheshadri N, Dou Z, Edinger AL, Du G, Braga VM, Zong WX. Vps34 regulates Rab7 and late endocytic trafficking through recruitment of the GTPase activating protein Armus. Journal of Cell Science. PMID 27793976 DOI: 10.1242/Jcs.192260  0.365
2016 Kim SM, Roy SG, Chen B, Nguyen TM, McMonigle RJ, McCracken AN, Zhang Y, Kofuji S, Hou J, Selwan E, Finicle BT, Nguyen TT, Ravi A, Ramirez MU, Wiher T, ... ... Edinger AL, et al. Targeting cancer metabolism by simultaneously disrupting parallel nutrient access pathways. The Journal of Clinical Investigation. PMID 27669461 DOI: 10.1172/Jci87148  0.729
2016 Perryman MS, Tessier J, Wiher T, O'Donoghue H, McCracken AN, Kim SM, Nguyen DG, Simitian GS, Viana M, Rafelski S, Edinger AL, Hanessian S. Effects of stereochemistry, saturation, and hydrocarbon chain length on the ability of synthetic constrained azacyclic sphingolipids to trigger nutrient transporter down-regulation, vacuolation, and cell death. Bioorganic & Medicinal Chemistry. PMID 27475534 DOI: 10.1016/J.Bmc.2016.07.038  0.46
2016 Selwan E, Finicle BT, Kim SM, Edinger AL. Attacking the supply wagons to starve cancer cells to death. Febs Letters. PMID 26938658 DOI: 10.1002/1873-3468.12121  0.461
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Edinger AL, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356  0.304
2015 McCracken AN, Edinger AL. Targeting cancer metabolism at the plasma membrane by limiting amino acid access through SLC6A14. The Biochemical Journal. 470: e17-9. PMID 26341486 DOI: 10.1042/BJ20150721  0.377
2015 Pone EJ, Lam T, Lou Z, Wang R, Chen Y, Liu D, Edinger AL, Xu Z, Casali P. B cell Rab7 mediates induction of activation-induced cytidine deaminase expression and class-switching in T-dependent and T-independent antibody responses. Journal of Immunology (Baltimore, Md. : 1950). 194: 3065-78. PMID 25740947 DOI: 10.4049/Jimmunol.1401896  0.345
2014 Guenther GG, Liu G, Ramirez MU, Mcmonigle RJ, Kim SM, Mccracken AN, Joo Y, Ushach I, Nguyen NL, Edinger AL. Loss of TSC2 confers resistance to ceramide and nutrient deprivation Oncogene. 33: 1776-1787. PMID 23604129 DOI: 10.1038/onc.2013.139  0.719
2013 McCracken AN, Edinger AL. Nutrient transporters: the Achilles' heel of anabolism. Trends in Endocrinology and Metabolism: Tem. 24: 200-8. PMID 23402769 DOI: 10.1016/j.tem.2013.01.002  0.495
2011 Romero Rosales K, Singh G, Wu K, Chen J, Janes MR, Lilly MB, Peralta ER, Siskind LJ, Bennett MJ, Fruman DA, Edinger AL. Sphingolipid-based drugs selectively kill cancer cells by down-regulating nutrient transporter proteins. The Biochemical Journal. 439: 299-311. PMID 21767261 DOI: 10.1042/Bj20110853  0.782
2010 Walsh CM, Edinger AL. The complex interplay between autophagy, apoptosis, and necrotic signals promotes T-cell homeostasis. Immunological Reviews. 236: 95-109. PMID 20636811 DOI: 10.1111/J.1600-065X.2010.00919.X  0.451
2010 Peralta ER, Martin BC, Edinger AL. Differential effects of TBC1D15 and mammalian Vps39 on Rab7 activation state, lysosomal morphology, and growth factor dependence. The Journal of Biological Chemistry. 285: 16814-21. PMID 20363736 DOI: 10.1074/Jbc.M110.111633  0.762
2010 Siskind LJ, Mullen TD, Romero Rosales K, Clarke CJ, Hernandez-Corbacho MJ, Edinger AL, Obeid LM. The BCL-2 protein BAK is required for long-chain ceramide generation during apoptosis. The Journal of Biological Chemistry. 285: 11818-26. PMID 20172858 DOI: 10.1074/Jbc.M109.078121  0.486
2009 Romero Rosales K, Peralta ER, Guenther GG, Wong SY, Edinger AL. Rab7 activation by growth factor withdrawal contributes to the induction of apoptosis. Molecular Biology of the Cell. 20: 2831-40. PMID 19386765 DOI: 10.1091/Mbc.E08-09-0911  0.727
2009 Guenther GG, Edinger AL. A new take on ceramide: starving cells by cutting off the nutrient supply. Cell Cycle (Georgetown, Tex.). 8: 1122-6. PMID 19282666 DOI: 10.4161/cc.8.8.8161  0.799
2009 Peralta ER, Edinger AL. Ceramide-induced starvation triggers homeostatic autophagy. Autophagy. 5: 407-9. PMID 19202357 DOI: 10.4161/Auto.5.3.7809  0.802
2009 Edinger AL. Starvation in the midst of plenty: making sense of ceramide-induced autophagy by analysing nutrient transporter expression. Biochemical Society Transactions. 37: 253-8. PMID 19143642 DOI: 10.1042/BST0370253  0.651
2008 Guenther GG, Peralta ER, Rosales KR, Wong SY, Siskind LJ, Edinger AL. Ceramide starves cells to death by downregulating nutrient transporter proteins. Proceedings of the National Academy of Sciences of the United States of America. 105: 17402-7. PMID 18981422 DOI: 10.1073/Pnas.0802781105  0.597
2008 Fruman DA, Edinger AL. Cancer therapy: staying current with AMPK. The Biochemical Journal. 412: e3-5. PMID 18466113 DOI: 10.1042/Bj20080823  0.321
2007 Edinger AL. Controlling cell growth and survival through regulated nutrient transporter expression. The Biochemical Journal. 406: 1-12. PMID 17645414 DOI: 10.1042/BJ20070490  0.476
2005 Edinger AL. Growth factors regulate cell survival by controlling nutrient transporter expression. Biochemical Society Transactions. 33: 225-7. PMID 15667313 DOI: 10.1042/BST0330225  0.548
2004 Edinger AL, Thompson CB. Death by design: apoptosis, necrosis and autophagy. Current Opinion in Cell Biology. 16: 663-9. PMID 15530778 DOI: 10.1016/J.Ceb.2004.09.011  0.471
2004 Edinger AL, Thompson CB. An activated mTOR mutant supports growth factor-independent, nutrient-dependent cell survival. Oncogene. 23: 5654-63. PMID 15133498 DOI: 10.1038/Sj.Onc.1207738  0.505
2003 Edinger AL, Linardic CM, Chiang GG, Thompson CB, Abraham RT. Differential effects of rapamycin on mammalian target of rapamycin signaling functions in mammalian cells. Cancer Research. 63: 8451-60. PMID 14679009  0.355
2003 Edinger AL, Cinalli RM, Thompson CB. Rab7 prevents growth factor-independent survival by inhibiting cell-autonomous nutrient transporter expression. Developmental Cell. 5: 571-82. PMID 14536059 DOI: 10.1016/S1534-5807(03)00291-0  0.53
2002 Edinger AL, Thompson CB. Akt maintains cell size and survival by increasing mTOR-dependent nutrient uptake. Molecular Biology of the Cell. 13: 2276-88. PMID 12134068 DOI: 10.1091/Mbc.01-12-0584  0.532
2002 Edinger AL, Thompson CB. Antigen-presenting cells control T cell proliferation by regulating amino acid availability. Proceedings of the National Academy of Sciences of the United States of America. 99: 1107-9. PMID 11830651 DOI: 10.1073/Pnas.042707999  0.46
2001 Plas DR, Talapatra S, Edinger AL, Rathmell JC, Thompson CB. Akt and Bcl-xL promote growth factor-independent survival through distinct effects on mitochondrial physiology. The Journal of Biological Chemistry. 276: 12041-8. PMID 11278698 DOI: 10.1074/Jbc.M010551200  0.452
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