Yohannes Tesfaigzi - Publications

Affiliations: 
Biomedical Sciences University of New Mexico, Albuquerque, NM, United States 
Area:
Cell Biology, Molecular Biology

108 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Nagasi ZH, Nommi N, Liu C, Tesfaigzi Y. Persistence of Emphysema Following Cessation of Cigarette Smoke Exposure Requires a Susceptibility Factor. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 38349118 DOI: 10.1152/ajplung.00342.2023  0.302
2023 Tesfaigzi Y, Curtis JL, Petrache I, Polverino F, Kheradmand F, Adcock IM, Rennard SI. Does COPD Originate from Different Cell Types? American Journal of Respiratory Cell and Molecular Biology. PMID 37584669 DOI: 10.1165/rcmb.2023-0175PS  0.311
2023 Rojas-Quintero J, Laucho-Contreras ME, Wang X, Fucci QA, Burkett PR, Kim SJ, Zhang D, Tesfaigzi Y, Li Y, Bhashyam AR, Zhang L, Khamas H, Celli B, Pilon AL, Polverino F, et al. CC16 augmentation reduces exaggerated COPD-like disease in Cc16-deficient mice. Jci Insight. PMID 36787195 DOI: 10.1172/jci.insight.130771  0.357
2021 Miller P, Qiao D, Rojas-Quintero J, Honigberg MC, Sperling AS, Gibson CJ, Bick AG, Niroula A, McConkey ME, Sandoval B, Miller B, Shi W, Viswanathan K, Leventhal MJ, Werner L, ... ... Tesfaigzi Y, et al. Association of Clonal Hematopoiesis with Chronic Obstructive Pulmonary Disease. Blood. PMID 34855941 DOI: 10.1182/blood.2021013531  0.324
2020 Wang X, Rojas-Quintero J, Zhang D, Nakajima T, Walker KH, Peh HY, Li Y, Fucci QA, Tesfaigzi Y, Owen CA. A disintegrin and metalloproteinase domain-15 deficiency leads to exaggerated cigarette smoke-induced chronic obstructive pulmonary disease (COPD)-like disease in mice. Mucosal Immunology. PMID 32690871 DOI: 10.1038/S41385-020-0325-3  0.451
2020 Tessema M, Tassew DD, Yingling CM, Do K, Picchi MA, Wu G, Petersen H, Randell S, Lin Y, Belinsky SA, Tesfaigzi Y. Identification of novel epigenetic abnormalities as sputum biomarkers for lung cancer risk among smokers and COPD patients. Lung Cancer (Amsterdam, Netherlands). 146: 189-196. PMID 32559455 DOI: 10.1016/J.Lungcan.2020.05.017  0.413
2019 Sakornsakolpat P, Prokopenko D, Lamontagne M, Reeve NF, Guyatt AL, Jackson VE, Shrine N, Qiao D, Bartz TM, Kim DK, Lee MK, Latourelle JC, Li X, Morrow JD, Obeidat M, ... ... Tesfaigzi Y, et al. Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations. Nature Genetics. PMID 30804561 DOI: 10.1038/S41588-018-0342-2  0.415
2019 Voic H, Li X, Jang JH, Zou C, Sundd P, Alder J, Rojas M, Chandra D, Randell S, Mallampalli RK, Tesfaigzi Y, Ryba T, Nyunoya T. RNA sequencing identifies common pathways between cigarette smoke exposure and replicative senescence in human airway epithelia. Bmc Genomics. 20: 22. PMID 30626320 DOI: 10.1186/S12864-018-5409-Z  0.365
2018 Tesfaigzi Y, Petersen H, Celli B, Owen C. Functional Studies of Single-Nucleotide Polymorphisms Suggest Heterogeneity in Chronic Obstructive Pulmonary Disease due to Susceptibility of Different Cell Types. Annals of the American Thoracic Society. 15: S285. PMID 30759009 DOI: 10.1513/Annalsats.201806-437Mg  0.446
2018 Abukhalaf J, Davidson R, Villalobos N, Meek P, Petersen H, Sood A, Tesfaigzi Y, Vazquez Guillamet R. Chronic Obstructive Pulmonary Disease Mortality, a Competing Risk Analysis. The Clinical Respiratory Journal. PMID 30257066 DOI: 10.1111/Crj.12963  0.328
2018 Mebratu YA, Tesfaigzi Y. Does the BCL-2 family member BIK control lung carcinogenesis? Molecular & Cellular Oncology. 5: e1435182. PMID 30250907 DOI: 10.1080/23723556.2018.1435182  0.399
2018 Petersen H, Sood A, Polverino F, Owen CA, Pinto-Plata V, Celli BR, Tesfaigzi Y. The Course of Lung Function in Middle-Aged Heavy Smokers: Incidence and Time to Early Onset of COPD. American Journal of Respiratory and Critical Care Medicine. PMID 30114375 DOI: 10.1164/Rccm.201805-0861Le  0.347
2018 Polverino F, Rojas-Quintero J, Wang X, Petersen H, Zhang L, Gai X, Higham A, Zhang D, Gupta K, Rout A, Yambayev I, Pinto-Plata V, Sholl LM, Cunoosamy D, Celli BR, ... ... Tesfaigzi Y, et al. A Disintegrin and A Metalloproteinase Domain-8 (ADAM8): A Novel Protective Proteinase in COPD. American Journal of Respiratory and Critical Care Medicine. PMID 29750543 DOI: 10.1164/Rccm.201707-1331Oc  0.366
2018 Vazquez Guillamet R, Petersen H, Meek P, Sood A, Tesfaigzi Y. Grading Severity of Productive Cough Based on Symptoms and Airflow Obstruction. Copd. 1-8. PMID 29697285 DOI: 10.1080/15412555.2018.1458218  0.361
2018 Petersen H, Vazquez Guillamet R, Meek P, Sood A, Tesfaigzi Y. Early Endotyping - A Chance for Intervention in COPD. American Journal of Respiratory Cell and Molecular Biology. PMID 29522352 DOI: 10.1165/Rcmb.2018-0002Ps  0.377
2018 Zhang C, Jones JT, Chand HS, Wathelet MG, Evans CM, Dickey B, Xiang J, Mebratu YA, Tesfaigzi Y. Noxa/HSP27 complex delays degradation of ubiquitylated IkBα in airway epithelial cells to reduce pulmonary inflammation. Mucosal Immunology. PMID 29363670 DOI: 10.1038/Mi.2017.117  0.413
2018 Chand HS, Harris JF, Tesfaigzi Y. IL-13 in LPS-Induced Inflammation Causes Bcl-2 Expression to Sustain Hyperplastic Mucous cells. Scientific Reports. 8: 436. PMID 29323189 DOI: 10.1038/S41598-017-18884-9  0.385
2018 Mebratu YA, Tesfaigzi Y. IL-17 Plays a Role in RSV-induced Lung Inflammation and Emphysema in Elastase and LPS-injured Mice. American Journal of Respiratory Cell and Molecular Biology. PMID 29314865 DOI: 10.1165/Rcmb.2017-0265Oc  0.375
2018 Sood A, Assad NA, Barnes PJ, Churg A, Gordon SB, Harrod KS, Irshad H, Kurmi OP, Martin WJ, Meek P, Mortimer K, Noonan CW, Perez-Padilla R, Smith KR, Tesfaigzi Y, et al. ERS/ATS workshop report on respiratory health effects of household air pollution. The European Respiratory Journal. 51. PMID 29301918 DOI: 10.1183/13993003.00698-2017  0.382
2017 Diaz AA, Rahaghi FN, Doyle TJ, Young TP, Maclean ES, Martinez CH, San José Estépar R, Guerra S, Tesfaigzi Y, Rosas IO, Washko GR, Wilson DO. Differences in Respiratory Symptoms and Lung Structure Between Hispanic and Non-Hispanic White Smokers: A Comparative Study. Chronic Obstructive Pulmonary Diseases (Miami, Fla.). 4: 297-304. PMID 29354674 DOI: 10.15326/Jcopdf.4.4.2017.0150  0.419
2017 Leng S, Picchi MA, Tesfaigzi Y, Wu G, Gauderman WJ, Xu F, Gilliland FD, Belinsky SA. Dietary nutrients associated with preservation of lung function in Hispanic and non-Hispanic white smokers from New Mexico. International Journal of Chronic Obstructive Pulmonary Disease. 12: 3171-3181. PMID 29133979 DOI: 10.2147/Copd.S142237  0.381
2017 Mebratu YA, Leyva-Baca I, Wathelet MG, Lacey N, Chand HS, Choi AMK, Tesfaigzi Y. Bik reduces hyperplastic cells by increasing Bak and activating DAPk1 to juxtapose ER and mitochondria. Nature Communications. 8: 803. PMID 28986568 DOI: 10.1038/S41467-017-00975-W  0.318
2017 Black C, Tesfaigzi Y, Bassein JA, Miller LA. Wildfire smoke exposure and human health: Significant gaps in research for a growing public health issue. Environmental Toxicology and Pharmacology. 55: 186-195. PMID 28892756 DOI: 10.1016/J.Etap.2017.08.022  0.316
2017 Chand HS, Mebratu YA, Kuehl PJ, Tesfaigzi Y. Blocking Bcl-2 resolves IL-13-mediated mucous cell hyperplasia in a Bik-dependent manner. The Journal of Allergy and Clinical Immunology. PMID 28784260 DOI: 10.1016/J.Jaci.2017.05.038  0.311
2017 Jones JT, Tassew DD, Herrera LK, Walton-Filipczak SR, Montera MA, Chand HS, Delgado M, Mebratu YA, Tesfaigzi Y. Extent of allergic inflammation depends on intermittent versus continuous sensitization to house dust mite. Inhalation Toxicology. 1-10. PMID 28413916 DOI: 10.1080/08958378.2017.1311389  0.333
2017 Hobbs BD, de Jong K, Lamontagne M, Bossé Y, Shrine N, Artigas MS, Wain LV, Hall IP, Jackson VE, Wyss AB, London SJ, North KE, Franceschini N, Strachan DP, Beaty TH, ... ... Tesfaigzi Y, et al. Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis. Nature Genetics. PMID 28166215 DOI: 10.1038/Ng.3752  0.401
2017 Polverino F, Laucho-Contreras ME, Petersen H, Bijol V, Sholl LM, Choi ME, Divo M, Pinto-Plata V, Chetta A, Tesfaigzi Y, Celli BR, Owen CA. A Pilot Study Linking Endothelial Injury in Lungs and Kidneys in COPD. American Journal of Respiratory and Critical Care Medicine. PMID 28085500 DOI: 10.1164/Rccm.201609-1765Oc  0.344
2016 Jang JH, Chand HS, Bruse S, Doyle-Eisele M, Royer C, McDonald J, Qualls C, Klingelhutz AJ, Lin Y, Mallampalli R, Tesfaigzi Y, Nyunoya T. Connective Tissue Growth Factor Promotes Pulmonary Epithelial Cell Senescence and Is Associated with COPD Severity. Copd. 1-10. PMID 28026993 DOI: 10.1080/15412555.2016.1262340  0.465
2016 Sood A, Petersen H, Qualls C, Meek PM, Vazquez-Guillamet R, Celli BR, Tesfaigzi Y. Spirometric variability in smokers: transitions in COPD diagnosis in a five-year longitudinal study. Respiratory Research. 17: 147. PMID 27832774 DOI: 10.1186/S12931-016-0468-7  0.356
2016 Chand HS, Mebratu YA, Montera M, Tesfaigzi Y. T cells suppress memory-dependent rapid mucous cell metaplasia in mouse airways. Respiratory Research. 17: 132. PMID 27765038 DOI: 10.1186/S12931-016-0446-0  0.383
2016 Mebratu YA, Smith KR, Agga GE, Tesfaigzi Y. Inflammation and emphysema in cigarette smoke-exposed mice when instilled with poly (I:C) or infected with influenza A or respiratory syncytial viruses. Respiratory Research. 17: 75. PMID 27363862 DOI: 10.1186/S12931-016-0392-X  0.349
2016 Diaz AA, Petersen H, Meek P, Sood A, Celli B, Tesfaigzi Y. Differences in Health-related Quality of Life Between New Mexican Hispanic and Non-Hispanic White Smokers. Chest. PMID 27321735 DOI: 10.1016/J.Chest.2016.06.011  0.311
2016 Behrsing H, Raabe H, Manuppello J, Bombick B, Curren R, Sullivan K, Sethi S, Phipps R, Tesfaigzi Y, Yan S, D'Ruiz C, Tarran R, Constant S, Phillips G, Gaça M, et al. Assessment of in vitro COPD models for tobacco regulatory science: Workshop proceedings, conclusions and paths forward for in vitro model use. Alternatives to Laboratory Animals : Atla. 44: 129-66. PMID 27256455 DOI: 10.1177/026119291604400206  0.382
2016 Laucho-Contreras ME, Polverino F, Tesfaigzi Y, Pilon A, Celli BR, Owen CA. Club Cell Protein 16 (CC16) Augmentation: A Potential Disease-modifying Approach for Chronic Obstructive Pulmonary Disease (COPD). Expert Opinion On Therapeutic Targets. 20: 869-83. PMID 26781659 DOI: 10.1517/14728222.2016.1139084  0.437
2016 Mebratu YA, Tipper J, Chand HS, Walton S, Harrod KS, Tesfaigzi Y. Bik Mediates Caspase-Dependent Cleavage of Viral Proteins to Promote Influenza A Virus Infection. American Journal of Respiratory Cell and Molecular Biology. 54: 664-73. PMID 26437021 DOI: 10.1165/Rcmb.2015-0133Oc  0.31
2016 Tesfaigzi Y, Awji E. Comparison of wood smoke and cigarette smoke in causing chronic mucous hypersecretion European Respiratory Journal. 48. DOI: 10.1183/13993003.Congress-2016.Pa4268  0.418
2016 Polverino F, Laucho-Conttreras M, Bijol V, Pinto-Plata V, Divo M, Choi M, Sholl L, Petersen H, Tesfaigzi Y, Celli B, Owen C. Evidence of renal and pulmonary endothelial dysfunction in chronic obstructive pulmonary disease (COPD) European Respiratory Journal. 48. DOI: 10.1183/13993003.Congress-2016.Pa4016  0.359
2015 Singh SP, Chand HS, Gundavarapu S, Saeed AI, Langley RJ, Tesfaigzi Y, Mishra NC, Sopori ML. HIF-1α Plays a Critical Role in the Gestational Sidestream Smoke-Induced Bronchopulmonary Dysplasia in Mice. Plos One. 10: e0137757. PMID 26361040 DOI: 10.1371/Journal.Pone.0137757  0.408
2015 Tessema M, Yingling CM, Picchi MA, Wu G, Liu Y, Weissfeld JL, Siegfried JM, Tesfaigzi Y, Belinsky SA. Epigenetic Repression of CCDC37 and MAP1B Links Chronic Obstructive Pulmonary Disease to Lung Cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 10: 1181-8. PMID 26200272 DOI: 10.1097/Jto.0000000000000592  0.388
2015 Lange P, Celli B, Agustí A, Boje Jensen G, Divo M, Faner R, Guerra S, Marott JL, Martinez FD, Martinez-Camblor P, Meek P, Owen CA, Petersen H, Pinto-Plata V, Schnohr P, ... ... Tesfaigzi Y, et al. Lung-Function Trajectories Leading to Chronic Obstructive Pulmonary Disease. The New England Journal of Medicine. 373: 111-22. PMID 26154786 DOI: 10.1056/Nejmoa1411532  0.383
2015 Awji EG, Seagrave JC, Tesfaigzi Y. Correlation of Cigarette Smoke-Induced Pulmonary Inflammation and Emphysema in C3H and C57Bl/6 Mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. 147: 75-83. PMID 26032511 DOI: 10.1093/Toxsci/Kfv108  0.365
2015 Meek P, Petersen H, Washko GR, Diaz AA, Kim V, Sood A, Tesfaigzi Y. Chronic Bronchitis is Associated with Worse Symptoms and Quality of Life than Chronic Airflow Obstruction. Chest. PMID 25741880 DOI: 10.1378/Chest.14-2240  0.325
2015 Leng S, Liu Y, Weissfeld JL, Thomas CL, Han Y, Picchi MA, Edlund CK, Willink RP, Gaither Davis AL, Do KC, Nukui T, Zhang X, Burki EA, Van Den Berg D, Romkes M, ... ... Tesfaigzi Y, et al. 15q12 variants, sputum gene promoter hypermethylation, and lung cancer risk: a GWAS in smokers. Journal of the National Cancer Institute. 107. PMID 25713168 DOI: 10.1093/Jnci/Djv035  0.315
2015 Laucho-Contreras ME, Polverino F, Gupta K, Taylor KL, Kelly E, Pinto-Plata V, Divo M, Ashfaq N, Petersen H, Stripp B, Pilon AL, Tesfaigzi Y, Celli BR, Owen CA. Protective role for club cell secretory protein-16 (CC16) in the development of COPD. The European Respiratory Journal. 45: 1544-56. PMID 25700379 DOI: 10.1183/09031936.00134214  0.496
2015 Chen W, Brehm JM, Manichaikul A, Cho MH, Boutaoui N, Yan Q, Burkart KM, Enright PL, Rotter JI, Petersen H, Leng S, Obeidat M, Bossé Y, Brandsma CA, Hao K, ... ... Tesfaigzi Y, et al. A genome-wide association study of chronic obstructive pulmonary disease in Hispanics. Annals of the American Thoracic Society. 12: 340-8. PMID 25584925 DOI: 10.1513/Annalsats.201408-380Oc  0.34
2015 Polverino F, Doyle-Eisele M, McDonald J, Wilder JA, Royer C, Laucho-Contreras M, Kelly EM, Divo M, Pinto-Plata V, Mauderly J, Celli BR, Tesfaigzi Y, Owen CA. A novel nonhuman primate model of cigarette smoke-induced airway disease. The American Journal of Pathology. 185: 741-55. PMID 25542772 DOI: 10.1016/J.Ajpath.2014.11.006  0.468
2015 Awji EG, Chand H, Bruse S, Smith KR, Colby JK, Mebratu Y, Levy BD, Tesfaigzi Y. Wood smoke enhances cigarette smoke-induced inflammation by inducing the aryl hydrocarbon receptor repressor in airway epithelial cells. American Journal of Respiratory Cell and Molecular Biology. 52: 377-86. PMID 25137396 DOI: 10.1165/Rcmb.2014-0142Oc  0.441
2015 Meek PM, Sood A, Petersen H, Belinsky SA, Tesfaigzi Y. Epigenetic change (GATA-4 gene methylation) is associated with health status in chronic obstructive pulmonary disease. Biological Research For Nursing. 17: 191-8. PMID 24973415 DOI: 10.1177/1099800414538113  0.336
2014 Chand HS, Montano G, Huang X, Randell SH, Mebratu Y, Petersen H, Tesfaigzi Y. A genetic variant of p53 restricts the mucous secretory phenotype by regulating SPDEF and Bcl-2 expression. Nature Communications. 5: 5567. PMID 25429397 DOI: 10.1038/Ncomms6567  0.316
2014 Moon HG, Kim SH, Gao J, Quan T, Qin Z, Osorio JC, Rosas IO, Wu M, Tesfaigzi Y, Jin Y. CCN1 secretion and cleavage regulate the lung epithelial cell functions after cigarette smoke American Journal of Physiology - Lung Cellular and Molecular Physiology. 307: L326-L337. PMID 24973403 DOI: 10.1152/Ajplung.00102.2014  0.42
2014 Craig VJ, Polverino F, Laucho-Contreras ME, Shi Y, Liu Y, Osorio JC, Tesfaigzi Y, Pinto-Plata V, Gochuico BR, Rosas IO, Owen CA. Mononuclear phagocytes and airway epithelial cells: novel sources of matrix metalloproteinase-8 (MMP-8) in patients with idiopathic pulmonary fibrosis. Plos One. 9: e97485. PMID 24828408 DOI: 10.1371/Journal.Pone.0097485  0.305
2014 Sood A, Petersen H, Meek P, Tesfaigzi Y. Reply from the authors. American Journal of Respiratory and Critical Care Medicine. 189: 871. PMID 24684365 DOI: 10.1164/Rccm.201401-0123Le  0.302
2014 Bruse S, Petersen H, Weissfeld J, Picchi M, Willink R, Do K, Siegfried J, Belinsky SA, Tesfaigzi Y. Increased methylation of lung cancer-associated genes in sputum DNA of former smokers with chronic mucous hypersecretion. Respiratory Research. 15: 2. PMID 24405663 DOI: 10.1186/1465-9921-15-2  0.349
2014 Jang JH, Bruse S, Liu Y, Duffy V, Zhang C, Oyamada N, Randell S, Matsumoto A, Thompson DC, Lin Y, Vasiliou V, Tesfaigzi Y, Nyunoya T. Aldehyde dehydrogenase 3A1 protects airway epithelial cells from cigarette smoke-induced DNA damage and cytotoxicity. Free Radical Biology & Medicine. 68: 80-6. PMID 24316006 DOI: 10.1016/J.Freeradbiomed.2013.11.028  0.374
2014 Chen W, Brehm JM, Boutaoui N, Soto-Quiros M, Avila L, Celli BR, Bruse S, Tesfaigzi Y, Celedón JC. Native American ancestry, lung function, and COPD in Costa Ricans. Chest. 145: 704-10. PMID 24306962 DOI: 10.1378/Chest.13-1308  0.407
2014 Delgado M, Tesfaigzi Y. Is BMF central for anoikis and autophagy? Autophagy. 10: 168-9. PMID 24225781 DOI: 10.4161/Auto.26759  0.348
2014 Nyunoya T, Mebratu Y, Contreras A, Delgado M, Chand HS, Tesfaigzi Y. Molecular processes that drive cigarette smoke-induced epithelial cell fate of the lung. American Journal of Respiratory Cell and Molecular Biology. 50: 471-82. PMID 24111585 DOI: 10.1165/Rcmb.2013-0348Tr  0.445
2014 Petersen H, Sood A, Meek PM, Shen X, Cheng Y, Belinsky SA, Owen CA, Washko G, Pinto-Plata V, Kelly E, Celli B, Tesfaigzi Y. Rapid lung function decline in smokers is a risk factor for COPD and is attenuated by angiotensin-converting enzyme inhibitor use. Chest. 145: 695-703. PMID 24008986 DOI: 10.1378/Chest.13-0799  0.351
2013 Lam HC, Cloonan SM, Bhashyam AR, Haspel JA, Singh A, Sathirapongsasuti JF, Cervo M, Yao H, Chung AL, Mizumura K, An CH, Shan B, Franks JM, Haley KJ, Owen CA, ... Tesfaigzi Y, et al. Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction. The Journal of Clinical Investigation. 123: 5212-30. PMID 24200693 DOI: 10.1172/Jci69636  0.412
2013 Knolle MD, Nakajima T, Hergrueter A, Gupta K, Polverino F, Craig VJ, Fyfe SE, Zahid M, Permaul P, Cernadas M, Montano G, Tesfaigzi Y, Sholl L, Kobzik L, Israel E, et al. Adam8 limits the development of allergic airway inflammation in mice. Journal of Immunology (Baltimore, Md. : 1950). 190: 6434-49. PMID 23670189 DOI: 10.4049/Jimmunol.1202329  0.391
2013 Contreras AU, Mebratu Y, Delgado M, Montano G, Hu CA, Ryter SW, Choi AM, Lin Y, Xiang J, Chand H, Tesfaigzi Y. Deacetylation of p53 induces autophagy by suppressing Bmf expression. The Journal of Cell Biology. 201: 427-37. PMID 23629966 DOI: 10.1083/Jcb.201205064  0.301
2012 Chand HS, Woldegiorgis Z, Schwalm K, McDonald J, Tesfaigzi Y. Acute inflammation induces insulin-like growth factor-1 to mediate Bcl-2 and Muc5ac expression in airway epithelial cells. American Journal of Respiratory Cell and Molecular Biology. 47: 784-91. PMID 22878411 DOI: 10.1165/Rcmb.2012-0079Oc  0.417
2012 Chand HS, Harris JF, Mebratu Y, Chen Y, Wright PS, Randell SH, Tesfaigzi Y. Intracellular insulin-like growth factor-1 induces Bcl-2 expression in airway epithelial cells Journal of Immunology. 188: 4581-4589. PMID 22461702 DOI: 10.4049/Jimmunol.1102673  0.368
2012 Leng S, Stidley CA, Liu Y, Edlund CK, Willink RP, Han Y, Landi MT, Thun M, Picchi MA, Bruse SE, Crowell RE, Van Den Berg D, Caporaso NE, Amos CI, Siegfried JM, ... Tesfaigzi Y, et al. Genetic determinants for promoter hypermethylation in the lungs of smokers: a candidate gene-based study. Cancer Research. 72: 707-15. PMID 22139380 DOI: 10.1158/0008-5472.Can-11-3194  0.349
2012 Bruse S, Petersen H, Tesfaigzi Y. The Hispanic Paradox and Chronic Obstructive Pulmonary Disease: Reply American Journal of Respiratory and Critical Care Medicine. 185: 1246-1247. DOI: 10.1164/Ajrccm.185.11.1246A  0.358
2011 Brehm JM, Hagiwara K, Tesfaigzi Y, Bruse S, Mariani TJ, Bhattacharya S, Boutaoui N, Ziniti JP, Soto-Quiros ME, Avila L, Cho MH, Himes B, Litonjua AA, Jacobson F, Bakke P, et al. Identification of FGF7 as a novel susceptibility locus for chronic obstructive pulmonary disease. Thorax. 66: 1085-90. PMID 21921092 DOI: 10.1136/Thoraxjnl-2011-200017  0.357
2011 Bruse S, Sood A, Petersen H, Liu Y, Leng S, Celedón JC, Gilliland F, Celli B, Belinsky SA, Tesfaigzi Y. New Mexican Hispanic smokers have lower odds of chronic obstructive pulmonary disease and less decline in lung function than non-Hispanic whites. American Journal of Respiratory and Critical Care Medicine. 184: 1254-60. PMID 21908412 DOI: 10.1164/Rccm.201103-0568Oc  0.413
2011 Nyunoya T, March TH, Tesfaigzi Y, Seagrave J. Antioxidant diet protects against emphysema, but increases mortality in cigarette smoke-exposed mice. Copd. 8: 362-8. PMID 21834692 DOI: 10.3109/15412555.2011.600361  0.35
2011 Abraham G, Zizzadoro C, Kacza J, Ellenberger C, Abs V, Franke J, Schoon HA, Seeger J, Tesfaigzi Y, Ungemach FR. Growth and differentiation of primary and passaged equine bronchial epithelial cells under conventional and air-liquid-interface culture conditions. Bmc Veterinary Research. 7: 26. PMID 21649893 DOI: 10.1186/1746-6148-7-26  0.336
2011 Smith KR, Leonard D, McDonald JD, Tesfaigzi Y. Inflammation, mucous cell metaplasia, and Bcl-2 expression in response to inhaled lipopolysaccharide aerosol and effect of rolipram. Toxicology and Applied Pharmacology. 253: 253-60. PMID 21504754 DOI: 10.1016/J.Taap.2011.04.001  0.329
2011 Mebratu YA, Schwalm K, Smith KR, Schuyler M, Tesfaigzi Y. Cigarette smoke suppresses Bik to cause epithelial cell hyperplasia and mucous cell metaplasia. American Journal of Respiratory and Critical Care Medicine. 183: 1531-8. PMID 21317312 DOI: 10.1164/Rccm.201011-1930Oc  0.478
2010 Sood A, Petersen H, Blanchette CM, Meek P, Picchi MA, Belinsky SA, Tesfaigzi Y. Wood smoke exposure and gene promoter methylation are associated with increased risk for COPD in smokers. American Journal of Respiratory and Critical Care Medicine. 182: 1098-104. PMID 20595226 DOI: 10.1164/Rccm.201002-0222Oc  0.394
2010 Chand HS, Schuyler M, Joste N, Hensler C, Tesfaigzi Y, Masten B, Schrader R, Lipscomb MF. Anti-IgE therapy results in decreased myeloid dendritic cells in asthmatic airways. The Journal of Allergy and Clinical Immunology. 125: 1157-1158.e5. PMID 20304471 DOI: 10.1016/J.Jaci.2010.01.020  0.353
2010 Pickett G, Seagrave J, Boggs S, Polzin G, Richter P, Tesfaigzi Y. Effects of 10 cigarette smoke condensates on primary human airway epithelial cells by comparative gene and cytokine expression studies. Toxicological Sciences : An Official Journal of the Society of Toxicology. 114: 79-89. PMID 20015843 DOI: 10.1093/Toxsci/Kfp298  0.376
2009 Hunninghake GM, Cho MH, Tesfaigzi Y, Soto-Quiros ME, Avila L, Lasky-Su J, Stidley C, Melén E, Söderhäll C, Hallberg J, Kull I, Kere J, Svartengren M, Pershagen G, Wickman M, et al. MMP12, lung function, and COPD in high-risk populations. The New England Journal of Medicine. 361: 2599-608. PMID 20018959 DOI: 10.1056/Nejmoa0904006  0.35
2009 Mebratu Y, Tesfaigzi Y. How ERK1/2 activation controls cell proliferation and cell death: Is subcellular localization the answer? Cell Cycle (Georgetown, Tex.). 8: 1168-75. PMID 19282669 DOI: 10.4161/Cc.8.8.8147  0.305
2008 Mebratu YA, Dickey BF, Evans C, Tesfaigzi Y. The BH3-only protein Bik/Blk/Nbk inhibits nuclear translocation of activated ERK1/2 to mediate IFNgamma-induced cell death. The Journal of Cell Biology. 183: 429-39. PMID 18981230 DOI: 10.1083/Jcb.200801186  0.375
2008 Sood A, Stidley CA, Picchi MA, Celedón JC, Gilliland F, Crowell RE, Belinsky SA, Tesfaigzi Y. Difference in airflow obstruction between Hispanic and non-Hispanic White female smokers. Copd. 5: 274-81. PMID 18972275 DOI: 10.1080/15412550802363345  0.376
2008 Tesfaigzi Y. Regulation of mucous cell metaplasia in bronchial asthma. Current Molecular Medicine. 8: 408-15. PMID 18691068 DOI: 10.2174/156652408785160961  0.385
2008 Mishra NC, Rir-Sima-Ah J, Langley RJ, Singh SP, Peña-Philippides JC, Koga T, Razani-Boroujerdi S, Hutt J, Campen M, Kim KC, Tesfaigzi Y, Sopori ML. Nicotine primarily suppresses lung Th2 but not goblet cell and muscle cell responses to allergens. Journal of Immunology (Baltimore, Md. : 1950). 180: 7655-63. PMID 18490768 DOI: 10.4049/Jimmunol.180.11.7655  0.398
2008 Wang X, Chen W, Zeng W, Bai L, Tesfaigzi Y, Belinsky SA, Lin Y. Akt-mediated eminent expression of c-FLIP and Mcl-1 confers acquired resistance to TRAIL-induced cytotoxicity to lung cancer cells. Molecular Cancer Therapeutics. 7: 1156-63. PMID 18483303 DOI: 10.1158/1535-7163.Mct-07-2183  0.313
2008 Schwalm K, Stevens JF, Jiang Z, Schuyler MR, Schrader R, Randell SH, Green FH, Tesfaigzi Y. Expression of the proapoptotic protein Bax is reduced in bronchial mucous cells of asthmatic subjects. American Journal of Physiology. Lung Cellular and Molecular Physiology. 294: L1102-9. PMID 18390829 DOI: 10.1152/Ajplung.00424.2007  0.396
2008 Xiang J, Rir-Sim-Ah J, Tesfaigzi Y. IL-9 and IL-13 induce mucous cell metaplasia that is reduced by IFN-gamma in a Bax-mediated pathway. American Journal of Respiratory Cell and Molecular Biology. 38: 310-7. PMID 17901408 DOI: 10.1165/Rcmb.2007-0078Oc  0.324
2007 Stout BA, Melendez K, Seagrave J, Holtzman MJ, Wilson B, Xiang J, Tesfaigzi Y. STAT1 activation causes translocation of Bax to the endoplasmic reticulum during the resolution of airway mucous cell hyperplasia by IFN-gamma. Journal of Immunology (Baltimore, Md. : 1950). 178: 8107-16. PMID 17548649 DOI: 10.4049/Jimmunol.178.12.8107  0.367
2007 Harris JF, Aden J, Lyons CR, Tesfaigzi Y. Resolution of LPS-induced airway inflammation and goblet cell hyperplasia is independent of IL-18. Respiratory Research. 8: 24. PMID 17352829 DOI: 10.1186/1465-9921-8-24  0.364
2006 Tesfaigzi Y, Meek P, Lareau S. Exacerbations of chronic obstructive pulmonary disease and chronic mucus hypersecretion. Clinical and Applied Immunology Reviews. 6: 21-36. PMID 32288656 DOI: 10.1016/J.Cair.2006.02.001  0.419
2006 Tesfaigzi Y, Myers OB, Stidley CA, Schwalm K, Picchi M, Crowell RE, Gilliland FD, Belinsky SA. Genotypes in matrix metalloproteinase 9 are a risk factor for COPD. International Journal of Chronic Obstructive Pulmonary Disease. 1: 267-78. PMID 18046864 DOI: 10.2147/Copd.2006.1.3.267  0.318
2006 Pierce J, Rir-Sima-Ah J, Estrada I, Wilder J, Strasser A, Tesfaigzi Y. Loss of pro-apoptotic Bim promotes accumulation of pulmonary T lymphocytes and enhances allergen-induced goblet cell metaplasia. American Journal of Physiology. Lung Cellular and Molecular Physiology. 291: L862-70. PMID 16782750 DOI: 10.1152/Ajplung.00516.2005  0.357
2006 Adler KB, Shapiro SD, Gallup M, Wu R, Randell SH, Holtzman MJ, Evans CM, Jacoby DB, Tesfaigzi Y, Rose MC, Mossman BT, Prince A, Reddy SP, Davis CW, Matthay MA. Airway epithelium, inflammation, and mechanisms of disease: A tribute to Carol B. Basbaum. American Journal of Respiratory Cell and Molecular Biology. 34: 523-6. PMID 16618787 DOI: 10.1165/Rcmb.F311  0.317
2006 Bartner LR, Robinson NE, Kiupel M, Tesfaigzi Y. Persistent mucus accumulation: a consequence of delayed bronchial mucous cell apoptosis in RAO-affected horses? American Journal of Physiology. Lung Cellular and Molecular Physiology. 291: L602-9. PMID 16500947 DOI: 10.1152/Ajplung.00500.2005  0.396
2006 Tesfaigzi Y. Roles of apoptosis in airway epithelia. American Journal of Respiratory Cell and Molecular Biology. 34: 537-47. PMID 16439804 DOI: 10.1165/Rcmb.2006-0014Oc  0.389
2005 Tesfaigzi Y, McDonald JD, Reed MD, Singh SP, De Sanctis GT, Eynott PR, Hahn FF, Campen MJ, Mauderly JL. Low-level subchronic exposure to wood smoke exacerbates inflammatory responses in allergic rats. Toxicological Sciences : An Official Journal of the Society of Toxicology. 88: 505-13. PMID 16162849 DOI: 10.1093/Toxsci/Kfi317  0.423
2005 Harris JF, Fischer MJ, Hotchkiss JR, Monia BP, Randell SH, Harkema JR, Tesfaigzi Y. Bcl-2 sustains increased mucous and epithelial cell numbers in metaplastic airway epithelium. American Journal of Respiratory and Critical Care Medicine. 171: 764-72. PMID 15618464 DOI: 10.1164/Rccm.200408-1108Oc  0.406
2005 Daheshia M, Harris JF, Johnson N, Tesfaigzi Y. Lps Priming Of Pulmonary Epithelium Affects The Response To A Secondary Challenge Experimental Lung Research. 31: 87-94. DOI: 10.1080/01902140591005076  0.308
2004 Wang SZ, Bao YX, Rosenberger CL, Tesfaigzi Y, Stark JM, Harrod KS. IL-12p40 and IL-18 modulate inflammatory and immune responses to respiratory syncytial virus infection. Journal of Immunology (Baltimore, Md. : 1950). 173: 4040-9. PMID 15356153 DOI: 10.4049/Jimmunol.173.6.4040  0.302
2004 Tesfaigzi Y, Harris JF, Hotchkiss JA, Harkema JR. DNA synthesis and Bcl-2 expression during development of mucous cell metaplasia in airway epithelium of rats exposed to LPS. American Journal of Physiology. Lung Cellular and Molecular Physiology. 286: L268-74. PMID 14527929 DOI: 10.1152/Ajplung.00172.2003  0.368
2003 Tesfaigzi Y, Wright PS, Belinsky SA. SPRR1B overexpression enhances entry of cells into the G0 phase of the cell cycle. American Journal of Physiology. Lung Cellular and Molecular Physiology. 285: L889-98. PMID 12832281 DOI: 10.1152/Ajplung.00065.2003  0.352
2003 Singh SP, Barrett EG, Kalra R, Razani-Boroujerdi S, Langley RJ, Kurup V, Tesfaigzi Y, Sopori ML. Prenatal cigarette smoke decreases lung cAMP and increases airway hyperresponsiveness. American Journal of Respiratory and Critical Care Medicine. 168: 342-7. PMID 12791581 DOI: 10.1164/Rccm.200211-1262Oc  0.424
2003 Foster JE, Gott K, Schuyler MR, Kozak W, Tesfaigzi Y. LPS-induced neutrophilic inflammation and Bcl-2 expression in metaplastic mucous cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. 285: L405-14. PMID 12704018 DOI: 10.1152/Ajplung.00249.2002  0.35
2002 Tesfaigzi Y. The role of apoptotic regulators in metaplastic mucous cells. Novartis Foundation Symposium. 248: 221-30; discussion 2. PMID 12568497 DOI: 10.1002/0470860790.Ch14  0.424
2002 Tesfaigzi Y, Fischer MJ, Daheshia M, Green FH, De Sanctis GT, Wilder JA. Bax is crucial for IFN-gamma-induced resolution of allergen-induced mucus cell metaplasia. Journal of Immunology (Baltimore, Md. : 1950). 169: 5919-25. PMID 12421976 DOI: 10.4049/Jimmunol.169.10.5919  0.33
2002 Shi ZO, Fischer MJ, De Sanctis GT, Schuyler MR, Tesfaigzi Y. IFN-gamma, but not Fas, mediates reduction of allergen-induced mucous cell metaplasia by inducing apoptosis. Journal of Immunology (Baltimore, Md. : 1950). 168: 4764-71. PMID 11971027 DOI: 10.4049/Jimmunol.168.9.4764  0.402
2002 Tesfaigzi Y, Singh SP, Foster JE, Kubatko J, Barr EB, Fine PM, McDonald JD, Hahn FF, Mauderly JL. Health effects of subchronic exposure to low levels of wood smoke in rats. Toxicological Sciences : An Official Journal of the Society of Toxicology. 65: 115-25. PMID 11752691 DOI: 10.1093/Toxsci/65.1.115  0.366
2001 Tesfaigzi Y, Rudolph K, Fischer MJ, Conn CA. Bcl-2 mediates sex-specific differences in recovery of mice from LPS-induced signs of sickness independent of IL-6. Journal of Applied Physiology. 91: 2182-2189. PMID 11641360 DOI: 10.1152/Jappl.2001.91.5.2182  0.334
2001 Wang S, Rosenberger CL, Espindola TM, Barrett EG, Tesfaigzi Y, Bice DE, Harrod KS. CCSP modulates airway dysfunction and host responses in an Ova-challenged mouse model American Journal of Physiology-Lung Cellular and Molecular Physiology. 281. PMID 11597923 DOI: 10.1152/Ajplung.2001.281.5.L1303  0.364
2001 Tesfaigzi Y, Kluger M, Kozak W. Clinical and cellular effects of cytochrome P-450 modulators Respiration Physiology. 128: 79-87. PMID 11535265 DOI: 10.1016/S0034-5687(01)00267-5  0.357
2001 Wilder JA, Collie D, Bice DE, Tesfaigzi Y, Lyons CR, Lipscomb MF. Ovalbumin aerosols induce airway hyperreactivity in naïve DO11.10 T cell receptor transgenic mice without pulmonary eosinophilia or OVA-specific antibody. Journal of Leukocyte Biology. 69: 538-547. DOI: 10.1189/Jlb.69.4.538  0.365
2000 Tesfaigzi Y, Fischer MJ, Martin AJ, Seagrave J. Bcl-2 in LPS- and allergen-induced hyperplastic mucous cells in airway epithelia of Brown Norway rats American Journal of Physiology-Lung Cellular and Molecular Physiology. 279. PMID 11076811 DOI: 10.1152/Ajplung.2000.279.6.L1210  0.376
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